Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA ligase (ATP) activity	LIG1 LIG3	2.05e-04	3	166	2	GO:0003910
GeneOntologyMolecularFunction	DNA ligase activity	LIG1 LIG3	2.05e-04	3	166	2	GO:0003909
GeneOntologyMolecularFunction	protein tyrosine phosphatase activator activity	IGFBP3 CD33	2.05e-04	3	166	2	GO:0008160
GeneOntologyMolecularFunction	protein phosphatase activator activity	PPP2R5C IGFBP3 CD33	3.52e-04	17	166	3	GO:0072542
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	KPNA4 RGPD4 RGPD1 RGPD3 KPNA3	4.74e-07	20	168	5	GO:0006607
GeneOntologyBiologicalProcess	homeostasis of number of cells	RAG1 HIF1A MECOM NBEA AP3B1 SKIL TRIM10 NOD2 SENP1 MERTK KIT ZBTB18 IL3 EPAS1	1.90e-05	448	168	14	GO:0048872
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	4.30e-05	9	168	3	GO:0033133
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD1 RGPD3	2.92e-05	8	171	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD1 RGPD3	6.19e-05	10	171	3	GO:0044614
GeneOntologyCellularComponent	inclusion body	RGPD4 RGPD1 PSMC4 URB2 RGPD3 HTT	9.68e-05	90	171	6	GO:0016234
GeneOntologyCellularComponent	nuclear pore	KPNA4 RGPD4 NUP107 RGPD1 RGPD3 KPNA3	1.83e-04	101	171	6	GO:0005643
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD1 RGPD3	1.83e-04	14	171	3	GO:0005642
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD1 RGPD3	4.01e-04	18	171	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD1 RGPD3	5.53e-04	20	171	3	GO:0042405
GeneOntologyCellularComponent	nuclear membrane	KPNA4 RGPD4 NUP107 DPY19L1 SUN1 RGPD1 SENP1 RGPD3 ANKRD17 ALOX5	6.21e-04	349	171	10	GO:0031965
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RGPD1 RGPD3	6.42e-04	21	171	3	GO:0106068
GeneOntologyCellularComponent	clathrin-coated vesicle	DENND1C AP3B1 ABCB4 SH3BP4 TYRP1 EGF VPS41 HTT	7.65e-04	237	171	8	GO:0030136
GeneOntologyCellularComponent	cytosolic proteasome complex	PSMC4 IDE	1.36e-03	7	171	2	GO:0031597
GeneOntologyCellularComponent	microtubule minus-end	CAMSAP1 CAMSAP2	1.36e-03	7	171	2	GO:0036449
MousePheno	decreased tumor latency	RGPD4 RGPD1 RGPD3 BUB1 RASAL2	7.90e-06	30	131	5	MP:0010308
MousePheno	elevated level of mitotic sister chromatid exchange	RGPD4 RGPD1 LIG3 RGPD3	1.23e-05	16	131	4	MP:0003701
MousePheno	abnormal tumor latency	RGPD4 RGPD1 RGPD3 BUB1 RASAL2	1.50e-05	34	131	5	MP:0010307
MousePheno	increased carcinoma incidence	RGPD4 RGPD1 GON4L TSC1 CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1	1.62e-05	197	131	10	MP:0002038
MousePheno	increased classified tumor incidence	RGPD4 RGPD1 GON4L TSC1 RET SKIL CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1 KIT	5.93e-05	381	131	13	MP:0010273
MousePheno	abnormal classified tumor incidence	RGPD4 RGPD1 GON4L TSC1 RET SKIL CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1 KIT	6.42e-05	384	131	13	MP:0020188
MousePheno	increased malignant tumor incidence	RGPD4 RGPD1 GON4L TSC1 CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1	7.80e-05	237	131	10	MP:0002018
MousePheno	increased organ/body region tumor incidence	RGPD4 RGPD1 GON4L TSC1 RET SKIL CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1 KIT	8.54e-05	395	131	13	MP:0010274
MousePheno	retina pigment epithelium atrophy	FAT1 ALMS1 MERTK	9.20e-05	10	131	3	MP:0005548
MousePheno	abnormal organ/body region tumor incidence	RGPD4 RGPD1 GON4L TSC1 RET SKIL CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1 KIT	9.94e-05	401	131	13	MP:0013152
MousePheno	increased tumor incidence	RGPD4 RAG1 ATR RGPD1 GON4L TSC1 RET SKIL CABLES1 CHUK ABCB4 LIG1 RGPD3 BUB1 KIT	1.31e-04	530	131	15	MP:0002020
MousePheno	small spleen	RAG1 ATR GON4L GHR PHKA1 GSTK1 POLQ KIT ZNF281 ALOX5 VPS13B NLK GAREM1	1.43e-04	416	131	13	MP:0000692
MousePheno	abnormal female reproductive system physiology	ATR NUP107 DPY19L1 KALRN SUN1 PSMC4 MECOM AP3B1 SKIL LIN28A CABLES1 CHUK ABCB4 GHR KANSL3 TYRP1 NEURL1 GREB1 KIT IL3	1.84e-04	876	131	20	MP:0003699
Domain	ARM-type_fold	KPNA4 ATR NBEA BTAF1 AP3B1 URB1 PPP2R5C HEATR6 PSME4 INTS4 TAF2 HTT KPNA3	9.64e-06	339	164	13	IPR016024
Domain	Rab_bind	RGPD4 RGPD1 RGPD3	2.27e-05	7	164	3	PF16704
Domain	GCC2_Rab_bind	RGPD4 RGPD1 RGPD3	2.27e-05	7	164	3	IPR032023
Domain	-	KPNA4 ATR BTAF1 AP3B1 PPP2R5C HEATR6 PSME4 INTS4 HTT KPNA3	2.74e-05	222	164	10	1.25.10.10
Domain	ARM-like	KPNA4 ATR NBEA BTAF1 AP3B1 PPP2R5C HEATR6 PSME4 INTS4 HTT KPNA3	2.74e-05	270	164	11	IPR011989
Domain	HEAT_REPEAT	ATR BTAF1 HEATR6 PSME4 INTS4 HTT	3.45e-05	70	164	6	PS50077
Domain	-	RGPD4 RGPD1 RGPD3	7.62e-05	10	164	3	1.10.220.60
Domain	HIF-1a_CTAD	HIF1A EPAS1	7.66e-05	2	164	2	PF08778
Domain	HIF-1_TAD_C	HIF1A EPAS1	7.66e-05	2	164	2	IPR014887
Domain	Grip	RGPD4 RGPD1 RGPD3	1.04e-04	11	164	3	SM00755
Domain	GRIP	RGPD4 RGPD1 RGPD3	1.04e-04	11	164	3	PF01465
Domain	Ran_BP1	RGPD4 RGPD1 RGPD3	1.38e-04	12	164	3	PF00638
Domain	RANBD1	RGPD4 RGPD1 RGPD3	1.38e-04	12	164	3	PS50196
Domain	GRIP_dom	RGPD4 RGPD1 RGPD3	1.38e-04	12	164	3	IPR000237
Domain	GRIP	RGPD4 RGPD1 RGPD3	1.38e-04	12	164	3	PS50913
Domain	RanBD	RGPD4 RGPD1 RGPD3	1.78e-04	13	164	3	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD1 RGPD3	1.78e-04	13	164	3	IPR000156
Domain	-	WDR88 VPS8 NBEA PLXNB2 BIRC6 WDR26 WDR19 WDR75 VPS41 WDR90 SEMA4A	1.79e-04	333	164	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR88 VPS8 NBEA PLXNB2 BIRC6 WDR26 WDR19 WDR75 VPS41 WDR90 SEMA4A	1.88e-04	335	164	11	IPR015943
Domain	DNA_ligase_ATP-dep_C	LIG1 LIG3	2.29e-04	3	164	2	IPR012309
Domain	DNA_ligase_ATP-dep_N	LIG1 LIG3	2.29e-04	3	164	2	IPR012308
Domain	DNA_ligase_ATP-dep_cent	LIG1 LIG3	2.29e-04	3	164	2	IPR012310
Domain	DNA_LIGASE_A2	LIG1 LIG3	2.29e-04	3	164	2	PS00333
Domain	DNA_LIGASE_A3	LIG1 LIG3	2.29e-04	3	164	2	PS50160
Domain	DNA_ligase_ATP-dep	LIG1 LIG3	2.29e-04	3	164	2	IPR000977
Domain	CAMSAP_CC1	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	PF17095
Domain	DNA_ligase_ATP-dep_CS	LIG1 LIG3	2.29e-04	3	164	2	IPR016059
Domain	CAMSAP_CKK	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	SM01051
Domain	PRC_barrel-like	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	IPR011033
Domain	DNA_ligase_A_M	LIG1 LIG3	2.29e-04	3	164	2	PF01068
Domain	CKK_domain	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	IPR014797
Domain	CAMSAP_CKK	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	PF08683
Domain	-	LIG1 LIG3	2.29e-04	3	164	2	1.10.3260.10
Domain	DNA_LIGASE_A1	LIG1 LIG3	2.29e-04	3	164	2	PS00697
Domain	CAMSAP_CC1	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	IPR031372
Domain	HIF_alpha_subunit	HIF1A EPAS1	2.29e-04	3	164	2	IPR021537
Domain	HIF-1	HIF1A EPAS1	2.29e-04	3	164	2	PF11413
Domain	DNA_ligase_A_C	LIG1 LIG3	2.29e-04	3	164	2	PF04679
Domain	DNA_ligase_A_N	LIG1 LIG3	2.29e-04	3	164	2	PF04675
Domain	CAMSAP	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	IPR032940
Domain	CKK	CAMSAP1 CAMSAP2	2.29e-04	3	164	2	PS51508
Domain	HEAT	ATR BTAF1 INTS4 HTT	8.25e-04	48	164	4	PF02985
Domain	NACHT	NLRP1 NOD2 NOD1	1.03e-03	23	164	3	PS50837
Domain	NACHT_NTPase	NLRP1 NOD2 NOD1	1.03e-03	23	164	3	IPR007111
Domain	Quinoprotein_ADH-like_supfam	WDR88 VPS8 WDR75 WDR90	1.20e-03	53	164	4	IPR011047
Domain	Clathrin	WDR19 VPS41	1.56e-03	7	164	2	PF00637
Domain	Arm_3	KPNA4 KPNA3	1.56e-03	7	164	2	PF16186
Domain	CAMSAP_CH	CAMSAP1 CAMSAP2	1.56e-03	7	164	2	PF11971
Domain	Importing_su_alpha	KPNA4 KPNA3	1.56e-03	7	164	2	IPR024931
Domain	IBB	KPNA4 KPNA3	1.56e-03	7	164	2	PF01749
Domain	Arm_3	KPNA4 KPNA3	1.56e-03	7	164	2	IPR032413
Domain	CAMSAP_CH	CAMSAP1 CAMSAP2	1.56e-03	7	164	2	IPR022613
Domain	HEAT	ATR BTAF1 INTS4 HTT	1.68e-03	58	164	4	IPR000357
Domain	CARD	NLRP1 NOD2 NOD1	1.85e-03	28	164	3	PF00619
Domain	Clathrin_H-chain/VPS_repeat	WDR19 VPS41	2.07e-03	8	164	2	IPR000547
Domain	IBB	KPNA4 KPNA3	2.07e-03	8	164	2	PS51214
Domain	Glyco_hydro_47	USF3 MAN1A2	2.07e-03	8	164	2	IPR001382
Domain	-	RGPD4 ATR RGPD1 SNX21 WDR19 RGPD3 VPS41	2.39e-03	207	164	7	1.25.40.10
Domain	-	ZGRF1 PSMC4 RNF213 NLRP1 CHD1 BTAF1 OPA1 ABCB4 EHD2 NOD2 NOD1 GET3 SULT6B1 ABCB11 POLQ	2.43e-03	746	164	15	3.40.50.300
Domain	CARD	NLRP1 NOD2 NOD1	2.49e-03	31	164	3	IPR001315
Domain	DUF3699	GARIN2 TASOR2	2.65e-03	9	164	2	IPR022168
Domain	Importin-a_IBB	KPNA4 KPNA3	2.65e-03	9	164	2	IPR002652
Domain	DUF3699	GARIN2 TASOR2	2.65e-03	9	164	2	PF12480
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	RAG1 HIF1A ATR TSC1 RET ABCB4 NOD2 GHR LIG1 LIG3 NOD1 IGFBP3 EGF ABCB11 IL3 ALOX5	2.96e-11	351	173	16	20453000
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KPNA4 BCL9L NUP107 DPY19L1 CHD1 BIRC6 LIN28A TASOR2 LIG1 LIG3 ABHD16B ALMS1 INTS4 SCAF11 TAF2 ZNF281 KPNA3	2.45e-10	469	173	17	27634302
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PITPNM2 FRAS1 B4GALNT4 KALRN ATP13A1 BTAF1 PLXNB2 BIRC6 FBXO46 CABLES1 SH3BP4 NOD2 KANSL3 PRR12 DIP2A URB1 FAT1 KANSL1 PSME4 IL17RE WDR90 CAMSAP1 ALOX5 HTT GAREM1	2.88e-10	1105	173	25	35748872
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD4 NUP107 ZGRF1 RGPD1 MECOM BIRC6 WDR26 PRR12 ALMS1 RGPD3 BUB1 ANKRD17 CAMSAP1 PYCR3	2.69e-08	418	173	14	34709266
Pubmed	A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses.	NOD2 NOD1 ANKRD17	1.21e-07	3	173	3	23711367
Pubmed	HIF-2α is indispensable for regulatory T cell function.	RAG1 HIF1A EPAS1	1.21e-07	3	173	3	33024109
Pubmed	Transcription Profiling of NOD-like Receptors in the Human Cornea with Disease.	NLRP1 NOD2 NOD1	4.82e-07	4	173	3	26902715
Pubmed	NLRs join TLRs as innate sensors of pathogens.	NLRP1 NOD2 NOD1	4.82e-07	4	173	3	15967716
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD4 PITPNM2 BCL9L HCN4 KALRN ATP13A1 SUN1 RGPD1 PSMC4 NBEA CBARP BIRC6 WDR26 OPA1 RAB3GAP1 PPP2R5C RGPD3 SYN2 CAMSAP1 CAMSAP2	1.13e-06	1139	173	20	36417873
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	ATR PSMC4 BTAF1 URB2 URB1 ABCB11 TAF2 CAMSAP1 KIT HTT	1.83e-06	285	173	10	32838362
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	KPNA4 RET ZNF804A TASOR2 SH3BP4 ZNF469 USF3 BUB1 WDR90 CAMSAP1 GAREM1 KPNA3	1.86e-06	430	173	12	35044719
Pubmed	Evaluation of Nod-like receptor (NLR) effector domain interactions.	NLRP1 NOD2 NOD1	2.39e-06	6	173	3	19337385
Pubmed	A novel pVHL-independent but NEMO-driven pathway in renal cancer promotes HIF stabilization.	HIF1A CHUK EPAS1	2.39e-06	6	173	3	26500060
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	RAG1 RET NOD2 GHR LIG1 LIG3 IGFBP3 EGF ABCB11 IL3 ALOX5	3.06e-06	374	173	11	19625176
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	KPNA4 KALRN RNF213 IDE AP3B1 WDR26 CHUK PHKA1 PSME4 KPNA3	3.25e-06	304	173	10	32235678
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	RAG1 RET NOD2 GHR LIG1 LIG3 IGFBP3 EGF ABCB11 IL3 ALOX5	3.65e-06	381	173	11	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	RAG1 RET NOD2 GHR LIG1 LIG3 IGFBP3 EGF ABCB11 IL3 ALOX5	3.74e-06	382	173	11	19170196
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	9037092
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	21205196
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	24403063
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	22821000
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	15710750
Pubmed	Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis.	NLRP1 NOD2 NOD1	4.17e-06	7	173	3	17620097
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	38657106
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	26632511
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	23818861
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD4 RGPD1 RGPD3	4.17e-06	7	173	3	20682751
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 ATR RALGAPB GON4L BTAF1 AP3B1 SH3BP4 PRR12 LIG3 DIP2A PSME4 BUB1 ANKRD17 RASAL2	5.20e-06	650	173	14	38777146
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF449 PITPNM2 HIF1A TDH RALGAPB RNF213 BTAF1 IDE SLC10A7 TASOR2 SH3BP4 KANSL3 SENP1 USF3 VPS41 ANKRD17 SCAF11 GREB1 VPS13B NLK HTT PDZD2	5.27e-06	1489	173	22	28611215
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KPNA4 NUP107 SUN1 RALGAPB PSMC4 RNF213 NBEA TSC1 CBARP IDE AP3B1 BIRC6 OPA1 PHKA1 PPP2R5C INTS4 LTBP1 KPNA3	5.50e-06	1049	173	18	27880917
Pubmed	A human MAP kinase interactome.	KPNA4 NCKAP5 MTPN SH3BP4 USF3 KANSL1 SIMC1 ANKRD17 CPLANE1 ZBTB18 EPAS1 GAREM1	6.46e-06	486	173	12	20936779
Pubmed	Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.	HIF1A EPAS1 KPNA3	6.65e-06	8	173	3	18187047
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD4 RGPD1 RGPD3	6.65e-06	8	173	3	21670213
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD4 RGPD1 RGPD3	6.65e-06	8	173	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD4 RGPD1 RGPD3	6.65e-06	8	173	3	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD4 RGPD1 RGPD3	6.65e-06	8	173	3	22262462
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD4 RGPD1 RGPD3	6.65e-06	8	173	3	28745977
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 VPS8 RALGAPB GON4L TSC1 URB2 OPA1 KANSL1 CAMSAP2 VPS13B PDZD2	6.82e-06	407	173	11	12693553
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	RAG1 RET NOD2 GHR LIG1 LIG3 IGFBP3 EGF ABCB11 IL3 ALOX5	9.36e-06	421	173	11	19692168
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	17887960
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	9733766
Pubmed	Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses.	NLRP1 NOD2 NOD1	9.94e-06	9	173	3	15107016
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	18394993
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	10601307
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD4 RGPD1 RGPD3	9.94e-06	9	173	3	28877029
Pubmed	Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.	ATR CDC7 LIG1 BUB1 ACOT2	1.36e-05	61	173	5	27694478
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	ATR DPY19L1 CHD1 SNX33 RET WDR26 CABLES1 CHUK MTPN CDC7 PHKA1 EGF BUB1 ANKRD36 MERTK CPLANE1	1.39e-05	910	173	16	36736316
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD4 RGPD1 RGPD3	1.41e-05	10	173	3	16332688
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD4 RGPD1 RGPD3	1.41e-05	10	173	3	27160050
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD4 RGPD1 RGPD3	1.41e-05	10	173	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD4 RGPD1 RGPD3	1.41e-05	10	173	3	21859863
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FRAS1 NUP107 ATP13A1 SUN1 RALGAPB PSMC4 CHD1 CBARP AP3B1 PLXNB2 MTPN SH3BP4 WDR19 DIP2A RAB3GAP1 URB1 SENP1 WDR75 PYCR3 VPS13B RASAL2	1.72e-05	1487	173	21	33957083
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	HIF1A RET CHUK GHR PPP2R5C EGF BUB1 KIT EPAS1 NLK	1.84e-05	371	173	10	25241761
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD4 RGPD1 RGPD3	1.94e-05	11	173	3	17069463
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD4 RGPD1 RGPD3	1.94e-05	11	173	3	34110283
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD4 RGPD1 RGPD3	1.94e-05	11	173	3	35771867
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	BCL9L NUP107 ATP13A1 SUN1 MTPN PRR12 SENP1 GSTK1 SUSD2 RGPD3 ANKRD17	2.00e-05	457	173	11	32344865
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	RGPD1 NBEA IDE URB2 AP3B1 WDR19 LIG3 RAB3GAP1 WDR75 ANKRD17 TAF2 ZNF281 RASAL2	2.04e-05	638	173	13	31182584
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KPNA4 KALRN ATP13A1 VPS26C NBEA NCKAP5 SKIL WDR26 CHUK MTPN WDR19 VPS9D1 DIP2A HEATR6 MAN1A2 ANKRD36 MERTK RASAL2 KPNA3	2.40e-05	1285	173	19	35914814
Pubmed	Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.	ABCB4 ABCB11	2.46e-05	2	173	2	30416103
Pubmed	The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival.	KALRN HTT	2.46e-05	2	173	2	29789657
Pubmed	Signalling pathways and molecular interactions of NOD1 and NOD2.	NOD2 NOD1	2.46e-05	2	173	2	16493424
Pubmed	ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement.	HIF1A EPAS1	2.46e-05	2	173	2	23437279
Pubmed	Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases.	ABCB4 ABCB11	2.46e-05	2	173	2	31886153
Pubmed	Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease.	RAG1 HTT	2.46e-05	2	173	2	34233199
Pubmed	Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke.	HIF1A EPAS1	2.46e-05	2	173	2	26746864
Pubmed	Loss of either hypoxia inducible factor 1 or 2 promotes lung cancer cell colonization.	HIF1A EPAS1	2.46e-05	2	173	2	21610325
Pubmed	Constitutive expression of HIF-α plays a major role in generation of clear-cell phenotype in human primary and metastatic renal carcinoma.	HIF1A EPAS1	2.46e-05	2	173	2	25046225
Pubmed	Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.	ABCB4 ABCB11	2.46e-05	2	173	2	35691019
Pubmed	Hypoxia induced HIF-1/HIF-2 activity alters trophoblast transcriptional regulation and promotes invasion.	HIF1A EPAS1	2.46e-05	2	173	2	26531845
Pubmed	Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking.	NOD2 NOD1	2.46e-05	2	173	2	20308305
Pubmed	Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.	HIF1A EPAS1	2.46e-05	2	173	2	20032376
Pubmed	The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability.	HIF1A EPAS1	2.46e-05	2	173	2	36482296
Pubmed	An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination.	LIG1 LIG3	2.46e-05	2	173	2	9001252
Pubmed	Low oxygen atmosphere facilitates proliferation and maintains undifferentiated state of umbilical cord mesenchymal stem cells in an hypoxia inducible factor-dependent manner.	HIF1A EPAS1	2.46e-05	2	173	2	24726658
Pubmed	Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.	NOD2 NOD1	2.46e-05	2	173	2	12871942
Pubmed	Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence.	HIF1A EPAS1	2.46e-05	2	173	2	17437013
Pubmed	Nucleotide oligomerization domains 1 and 2: regulation of expression and function in preadipocytes.	NOD2 NOD1	2.46e-05	2	173	2	18714036
Pubmed	Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy.	ABCB4 ABCB11	2.46e-05	2	173	2	16890614
Pubmed	Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands.	HIF1A EPAS1	2.46e-05	2	173	2	17562539
Pubmed	Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites.	KIT IL3	2.46e-05	2	173	2	9510253
Pubmed	[Expression of HIF-1alpha mRNA and HIF-2alpha mRNA in placentas of pregnant women with intrahepatic cholestasis of pregnancy].	HIF1A EPAS1	2.46e-05	2	173	2	17718430
Pubmed	The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha.	HIF1A EPAS1	2.46e-05	2	173	2	17804822
Pubmed	IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells.	RAG1 CHUK	2.46e-05	2	173	2	25376833
Pubmed	Hypoxia and the expression of HIF-1alpha and HIF-2alpha in the retina of streptozotocin-injected mice and rats.	HIF1A EPAS1	2.46e-05	2	173	2	20005221
Pubmed	Aggregatibacter actinomycetemcomitans outer membrane vesicles are internalized in human host cells and trigger NOD1- and NOD2-dependent NF-κB activation.	NOD2 NOD1	2.46e-05	2	173	2	25024364
Pubmed	Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha.	HIF1A EPAS1	2.46e-05	2	173	2	20140661
Pubmed	Contribution of the NOD1/CARD4 insertion/deletion polymorphism +32656 to inflammatory bowel disease in Northern Europe.	NOD2 NOD1	2.46e-05	2	173	2	17285593
Interaction	SHC4 interactions	NBEA RET CHUK KIT GAREM1	9.17e-07	22	169	5	int:SHC4
GeneFamily	DNA ligases\|Nucleotide excision repair	LIG1 LIG3	1.06e-04	3	108	2	1247
GeneFamily	Cadherin related	FAT3 RET FAT1	1.33e-04	17	108	3	24
GeneFamily	NLR family	NLRP1 NOD2 NOD1	4.33e-04	25	108	3	666
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	NLRP1 NOD2 NOD1	7.48e-04	30	108	3	959
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	RET MERTK KIT	1.74e-03	40	108	3	321
GeneFamily	ATP binding cassette subfamily B	ABCB4 ABCB11	1.88e-03	11	108	2	806
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN1A1 ERMAP	3.53e-03	15	108	2	458
GeneFamily	WD repeat domain containing	WDR88 NBEA WDR26 WDR19 WDR75 WDR90	4.89e-03	262	108	6	362
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD4 RGPD1 SNX21 RGPD3	5.01e-03	115	108	4	769
GeneFamily	Armadillo repeat containing\|Importins	KPNA4 KPNA3	5.08e-03	18	108	2	596
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	ZNF449 ATR NUP107 TDH ZGRF1 PIWIL2 PNLDC1 IDE URB2 TASOR2 CHUK CDC7 PHKA1 LIG1 URB1 PPP2R5C ALMS1 WDR75 BUB1 CPLANE1 KIT RASAL2 HTT	1.40e-07	820	168	23	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	ATR NUP107 TDH RNF213 TSC1 PIWIL2 PNLDC1 IDE URB2 RET TASOR2 CDC7 URB1 PPP2R5C ALMS1 WDR75 GET3 BUB1 CPLANE1 KIT RASAL2	1.81e-06	810	168	21	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	B4GALNT4 KALRN FAT3 CHD1 IDE RET SKIL BIRC6 WDR26 ZNF804A LIG3 HEATR6 MAN1A2 KANSL1 IL17RE CNTNAP4 LTBP1 CAMSAP1 CPLANE1 CAMSAP2 VPS13B	2.11e-06	818	168	21	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	FAT3 CHD1 IDE SKIL BIRC6 WDR26 LIG3 HEATR6 MAN1A2 KANSL1 CAMSAP1 CPLANE1 CAMSAP2 VPS13B	2.46e-06	385	168	14	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	FAT3 CHD1 IDE SKIL SLC10A7 GHR LIG3 HEATR6 MAN1A2 KANSL1 CPLANE1 CAMSAP2 VPS13B	8.01e-06	369	168	13	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	ATR NUP107 TDH ZGRF1 RNF213 PIWIL2 PNLDC1 IDE URB2 TASOR2 CDC7 LIG1 URB1 PPP2R5C ALMS1 WDR75 GET3 BUB1 CPLANE1 KIT	8.34e-06	822	168	20	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	ATR TDH ZGRF1 PIWIL2 PNLDC1 TASOR2 CHUK CDC7 PHKA1 ALMS1 BUB1 CPLANE1 KIT	1.26e-05	385	168	13	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	HIF1A ATR RNF213 TSC1 PIWIL2 BIRC6 LIN28A TASOR2 CHUK SENP1 KANSL1 ALMS1 BUB1 SYN2 ANKRD17 GREB1 CPLANE1 RASAL2	4.53e-05	776	168	18	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000	DPY19L1 GON4L IDE BIRC6 LIG3 MAN1A2 KANSL1 CPLANE1 CAMSAP2 VPS13B	4.54e-05	261	168	10	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	HIF1A FAT3 IDE SKIL SLC10A7 BIRC6 GHR MAN1A2 KANSL1 CPLANE1 CAMSAP2	6.69e-05	330	168	11	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500	ATR ZGRF1 TASOR2 CHUK PHKA1 ALMS1 CPLANE1	7.62e-05	129	168	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500	KALRN RET BIRC6 ZNF804A LIG3 HEATR6 MAN1A2 KANSL1 IL17RE LTBP1 CPLANE1 CAMSAP2	1.23e-04	416	168	12	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	FAT3 BIRC6 WDR26 GHR LIG3 MAN1A2 KANSL1 CAMSAP1 CPLANE1 CAMSAP2	1.98e-04	312	168	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	KALRN FAT3 CHD1 IDE SKIL SLC10A7 TASOR2 GHR LIG3 HEATR6 MAN1A2 KANSL1 CNTNAP4 CPLANE1 CAMSAP2 VPS13B PDZD2	2.32e-04	806	168	17	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SLC9A9 B4GALNT4 KALRN FAT3 BIRC6 WDR26 GHR LIG3 HEATR6 MAN1A2 KANSL1 IL17RE CNTNAP4 CAMSAP1 CPLANE1 CAMSAP2 PDZD2	2.32e-04	806	168	17	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	ATR TSC1 TASOR2 ALMS1 CPLANE1 RASAL2	2.44e-04	110	168	6	gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500	KALRN BIRC6 LIG3 HEATR6 MAN1A2 KANSL1 CPLANE1 CAMSAP2	2.67e-04	209	168	8	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500	ATR TDH PIWIL2 PNLDC1 IDE URB2 CDC7 URB1 WDR75 BUB1 KIT	2.69e-04	387	168	11	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500	IDE BIRC6 KANSL1 VPS41 CPLANE1 CAMSAP2	3.40e-04	117	168	6	gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RNF213 CHD1 BTAF1 GARIN2 PPP2R5C KANSL1 PSME4 ANKRD36 IBA57-DT	1.09e-08	156	173	9	1545169694f686d28648a68b552c2ae606599d66
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	RNF152 TDH NCKAP5 ZNF804A ABCB11 MERTK EPAS1 RASAL2 PDZD2	5.26e-08	187	173	9	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 SH3BP4 FAT1 GRAMD2B GAREM1	5.88e-07	182	173	8	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ATR BIRC6 TASOR2 USF3 SCAF11 CPLANE1 ZNF281 VPS13B	9.15e-07	193	173	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	MECOM SKIL SH3BP4 IGFBP3 CNTNAP4 LTBP1 MERTK EPAS1	1.20e-06	200	173	8	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKAP5 SNX33 DENND1C VPS9D1 OTUD7A WDR90 MERTK	4.49e-06	169	173	7	15a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	RAG1 PLXNB2 NME8 PHEX IGFBP3 DNASE1L3 LRRC36	5.86e-06	176	173	7	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	KALRN SUN1 RNF213 URB1 KANSL1 ZNF415 HTT	6.09e-06	177	173	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 FAT1 GRAMD2B GAREM1	8.72e-06	187	173	7	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RNF213 CHD1 BTAF1 BIRC6 TASOR2 KANSL1 ANKRD36	9.02e-06	188	173	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 FAT1 GRAMD2B GAREM1	1.00e-05	191	173	7	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF213 NLRP1 CHD1 BTAF1 PPP2R5C KANSL1 ANKRD36	1.03e-05	192	173	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RNF152 MECOM NCKAP5 KIT EPAS1 LRRC36	1.07e-05	193	173	7	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 FAT1 GRAMD2B GAREM1	1.07e-05	193	173	7	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 MECOM NCKAP5 MERTK KIT EPAS1 RASAL2	1.07e-05	193	173	7	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NBEA PLXNB2 FAT1 MYO3B ALOX5 VWA5B1 GAREM1	1.11e-05	194	173	7	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NBEA PLXNB2 FAT1 MYO3B ALOX5 VWA5B1 GAREM1	1.14e-05	195	173	7	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	Healthy/Control-cDC\|World / Disease group and Cell class	NCKAP5 SH3BP4 NOD2 ZNF469 CD33 SEMA4A DNASE1L3	1.22e-05	197	173	7	4497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCell	Healthy/Control-cDC\|Healthy/Control / Disease group and Cell class	NCKAP5 SH3BP4 NOD2 ZNF469 CD33 SEMA4A DNASE1L3	1.22e-05	197	173	7	926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF213 BTAF1 DIP2A PPP2R5C KANSL1 ANKRD36 VPS13B	1.31e-05	199	173	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	AP3B1 KANSL3 SENP1 GET3 CAMSAP1 CAMSAP2 RASAL2	1.35e-05	200	173	7	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	(54)_pDC\|World / shred on Cell_type and subtype	RET NME8 SH3BP4 PHEX ZBTB18 DNASE1L3 LRRC36	1.48e-05	203	173	7	b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 SLC26A5 DENND1C CD33 SEMA4A ALOX5	3.00e-05	153	173	6	af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 SLC26A5 DENND1C CD33 SEMA4A ALOX5	3.00e-05	153	173	6	984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 FAT3 ZNF804A BTN1A1 DNASE1L3 VWA5B1	3.22e-05	155	173	6	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SNX21 SLC10A7 MERTK CAMSAP1 KIT NLK	3.85e-05	160	173	6	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 MTPN ARR3 ZBTB18 VWA5B1 NLK	3.99e-05	161	173	6	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC7 ZNF469 FAT1 KIAA1755 POLQ DNASE1L3	4.42e-05	164	173	6	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT3 NCKAP5 RET SIMC1 NEURL1 KIT	4.57e-05	165	173	6	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	GPR21 MECOM EHD2 FAT1 KIT PDZD2	4.73e-05	166	173	6	9788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT3 NCKAP5 RET SIMC1 NEURL1 KIT	5.05e-05	168	173	6	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	5.05e-05	168	173	6	6a233045638cb83dab64789b996b7598c325001e
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDC7 LIG1 URB1 BUB1 DKKL1 DNASE1L3	5.40e-05	170	173	6	badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR KALRN MYO3B SULT6B1 POLQ G6PC1	5.40e-05	170	173	6	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF213 CHD1 BTAF1 PPP2R5C KANSL1 ANKRD36	5.58e-05	171	173	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	TRIM10 CDC7 LIG1 BUB1 POLQ IL3	5.76e-05	172	173	6	8d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN TDH SMYD1 GARIN2 NEURL1 ALOX5	5.95e-05	173	173	6	f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	RNF152 WDR88 FAT3 RET NEURL1 KIT	6.14e-05	174	173	6	7e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	RNF152 WDR88 FAT3 RET NEURL1 KIT	6.34e-05	175	173	6	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 KALRN MTPN ZBTB18 DKKL1 VWA5B1	6.34e-05	175	173	6	ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AP3B1 LIG3 RAB3GAP1 USF3 SIMC1 IL3	6.34e-05	175	173	6	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	RAG1 PLXNB2 NME8 PHEX DNASE1L3 LRRC36	6.34e-05	175	173	6	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 KALRN MTPN ZBTB18 DKKL1 VWA5B1	6.34e-05	175	173	6	21f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	PLXNB2 NME8 PHEX IGFBP3 DNASE1L3 LRRC36	6.54e-05	176	173	6	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NBEA PHKA1 ADO CD33 KIT ALOX5	6.54e-05	176	173	6	0d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	KALRN SUN1 RNF213 URB1 ZNF415 HTT	6.54e-05	176	173	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	NS-moderate-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	6.75e-05	177	173	6	99500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR RET CABLES1 IL17RE SUSD2 DKKL1	6.96e-05	178	173	6	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMYD1 WDR19 NOD1 IGFBP3 SUSD2 PDZD2	7.18e-05	179	173	6	adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	7.18e-05	179	173	6	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	7.41e-05	180	173	6	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 FAT1 GAREM1	7.41e-05	180	173	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	8.11e-05	183	173	6	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RNF152 NCKAP5 SUSD2 KIAA1755 G6PC1 PDZD2	8.11e-05	183	173	6	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM202 PSME4 SIMC1 MERTK NLK	8.30e-05	114	173	5	84318a25a701331ccd5e68221239c543b9c0cc54
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 KALRN SLC6A17 FAT3 FAT1 CNTNAP4	8.36e-05	184	173	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	8.36e-05	184	173	6	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 KALRN SLC6A17 FAT3 FAT1 CNTNAP4	8.36e-05	184	173	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 KALRN SLC6A17 FAT3 FAT1 CNTNAP4	8.36e-05	184	173	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMYD1 ZGRF1 LIG1 BUB1 WDR90 POLQ	8.36e-05	184	173	6	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	SUN1 RNF213 SLC10A7 BIRC6 URB1 POLQ	8.61e-05	185	173	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC9A9 ZNF804A GHR PHKA1 FAT1 GREB1	8.87e-05	186	173	6	948815663c212c4311329d503b5991cbbbff9808
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	SUN1 RNF213 SLC10A7 BIRC6 URB1 POLQ	8.87e-05	186	173	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	IDE BIRC6 RAB3GAP1 ALMS1 SCAF11 VPS13B	8.87e-05	186	173	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B4GALNT4 GPR21 SMYD1 RET IL17RE DKKL1	9.14e-05	187	173	6	fae08f34dc4b15352bd4d10bc6c924fe119b5d5e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN NLRP1 NOD1 DNASE1L3 EPAS1 RASAL2	9.14e-05	187	173	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B4GALNT4 GPR21 SMYD1 RET IL17RE DKKL1	9.14e-05	187	173	6	e6b140b9fb582abf07aa6ea9bc437de3ba0d6de1
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLC9A9 MECOM NCKAP5 GHR TYRP1 LTBP1	9.14e-05	187	173	6	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	9.14e-05	187	173	6	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM KANSL1 EGF MYO3B ANKRD17 NLK	9.68e-05	189	173	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA FAT1 GRAMD2B GAREM1	9.97e-05	190	173	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	9.97e-05	190	173	6	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 SH3BP4 KANSL1 EGF GRAMD2B LTBP1	9.97e-05	190	173	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC9A9 ZNF804A GHR PHKA1 MYO3B GREB1	9.97e-05	190	173	6	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	Mesenchymal_cells-Smooth_muscle\|World / Lineage and Cell class	RNF152 MYOM1 SLC6A17 EHD2 EPAS1 RASAL2	9.97e-05	190	173	6	5aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RNF152 NCKAP5 MERTK KIT LRRC36	9.97e-05	190	173	6	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 FAT3 NCKAP5 RET NEURL1 KIT	1.03e-04	191	173	6	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	HIF1A MECOM IGFBP3 LTBP1 EPAS1 PDZD2	1.03e-04	191	173	6	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A9 NLRP1 ZNF804A NOD2 CD33 ALOX5	1.09e-04	193	173	6	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NUP107 ZGRF1 LIG1 BUB1 OTUD7A POLQ	1.09e-04	193	173	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	NBEA PLXNB2 SH3BP4 PHEX ZBTB18 DNASE1L3	1.12e-04	194	173	6	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DPY19L1 LIG1 ALMS1 WDR90 ANKRD36 CPLANE1	1.12e-04	194	173	6	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 MECOM FAT1 EGF MYO3B GAREM1	1.12e-04	194	173	6	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 MECOM NCKAP5 KIT EPAS1 RASAL2	1.12e-04	194	173	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DPY19L1 LIG1 ALMS1 BUB1 WDR90 ANKRD36	1.12e-04	194	173	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF449 FAT3 CD33 NEURL1 KIT ALOX5	1.15e-04	195	173	6	c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCKAP5 SH3BP4 ZNF469 CD33 SEMA4A DNASE1L3	1.15e-04	195	173	6	4cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 MECOM NBEA NCKAP5 FAT1 GRAMD2B	1.15e-04	195	173	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 MECOM PLXNB2 FAT1 IGFBP3 EPAS1	1.18e-04	196	173	6	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN NBEA MAN1A2 SYN2 ANKRD36 RASAL2	1.18e-04	196	173	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 KALRN FAT3 ZNF804A KIAA1755 LTBP1	1.18e-04	196	173	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FAT3 MECOM FAT1 MYO3B NLK	1.18e-04	196	173	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PITPNM2 NCKAP5 FAT1 SYN2 LTBP1 EPAS1	1.18e-04	196	173	6	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 KALRN FAT3 ZNF804A KIAA1755 LTBP1	1.18e-04	196	173	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 KALRN FAT3 GHR TYRP1 LTBP1	1.18e-04	196	173	6	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCKAP5 SH3BP4 PHEX CD33 SEMA4A DNASE1L3	1.22e-04	197	173	6	89fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	HIF1A RNF213 CHD1 SKIL KANSL1 SCAF11	1.22e-04	197	173	6	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	Healthy_donor-cDC\|World / disease group, cell group and cell class (v2)	NCKAP5 SH3BP4 ZNF469 CD33 SEMA4A DNASE1L3	1.22e-04	197	173	6	a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FAT3 NCKAP5 SNX21 RET KIT DKKL1	1.25e-04	198	173	6	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF1A SUN1 MTPN EHD2 VPS41 SCAF11	1.25e-04	198	173	6	2f03f8897dd7cce6d8296638e14e11ec16bcf624
Disease	Colorectal Carcinoma	KALRN CHD1 RET ZNF804A CABLES1 ABCB4 LIG1 LIG3 FAT1 IGFBP3 BUB1 NEURL1 ABCB11 CAMSAP2 DNASE1L3 RASAL2	2.10e-06	702	164	16	C0009402
Disease	reticulocyte count	PITPNM2 ATR IP6K1 PLXNB2 BIRC6 TRIM10 ABCB4 ZNF469 FAT1 SENP1 NOD1 KANSL1 EGF CD33 SYN2 TAF2 ALOX5 PDZD2 KPNA3	6.10e-06	1045	164	19	EFO_0007986
Disease	reticulocyte measurement	PITPNM2 ATR IP6K1 PLXNB2 BIRC6 GARIN2 TRIM10 ABCB4 ZNF469 FAT1 SENP1 NOD1 KANSL1 EGF CD33 SYN2 ALOX5 PDZD2 KPNA3	6.80e-06	1053	164	19	EFO_0010700
Disease	autism spectrum disorder (implicated_via_orthology)	SLC9A9 NBEA TSC1 CHD1 WDR75 CNTNAP4 SYN2	2.37e-05	152	164	7	DOID:0060041 (implicated_via_orthology)
Disease	Colorectal Neoplasms	CHD1 RET CABLES1 ABCB4 FAT1 IGFBP3 BUB1 NEURL1 ABCB11	2.65e-05	277	164	9	C0009404
Disease	Lung diseases	HIF1A RET AP3B1 NME8 KIT	7.59e-05	78	164	5	C0024115
Disease	Progressive intrahepatic cholestasis (disorder)	ABCB4 ABCB11	9.18e-05	3	164	2	C0268312
Disease	Progressive familial intrahepatic cholestasis type 3	ABCB4 ABCB11	9.18e-05	3	164	2	cv:C1865643
Disease	Cholestasis, benign recurrent intrahepatic 1	ABCB4 ABCB11	9.18e-05	3	164	2	C4551899
Disease	PR interval	HCN4 KALRN SUN1 NCKAP5 CDC7 ZNF469 FAT1 OTUD7A KIAA1755 EPAS1 GAREM1	1.09e-04	495	164	11	EFO_0004462
Disease	intrahepatic cholestasis (is_implicated_in)	ABCB4 ABCB11	1.83e-04	4	164	2	DOID:1852 (is_implicated_in)
Disease	Cholestasis, progressive familial intrahepatic 1	ABCB4 ABCB11	1.83e-04	4	164	2	C4551898
Disease	Disorder of eye	FRAS1 OPA1 TYRP1 ALMS1 SEMA4A MERTK CPLANE1	1.92e-04	212	164	7	C0015397
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	RET MERTK EPAS1	2.75e-04	23	164	3	C1708353
Disease	acute kidney failure (implicated_via_orthology)	HIF1A ALOX5 EPAS1	4.47e-04	27	164	3	DOID:3021 (implicated_via_orthology)
Disease	clubfoot (implicated_via_orthology)	FRAS1 RET	4.54e-04	6	164	2	DOID:11836 (implicated_via_orthology)
Disease	Cholangitis, Sclerosing	HIF1A ABCB4	4.54e-04	6	164	2	C0008313
Disease	rhegmatogenous retinal detachment	FAT3 PYCR3	4.54e-04	6	164	2	EFO_0005240
Disease	Alzheimer's disease (is_marker_for)	HIF1A ATR IDE OPA1 IGFBP3 EGF IL3	6.11e-04	257	164	7	DOID:10652 (is_marker_for)
Disease	lifestyle measurement, diastolic blood pressure	NCKAP5 GAREM1	6.33e-04	7	164	2	EFO_0006336, EFO_0010724
Disease	Prostatic Neoplasms	RAG1 HIF1A ATR CHD1 GHR IGFBP3 EGF GSTK1 INTS4 GREB1 ALOX5	6.95e-04	616	164	11	C0033578
Disease	Malignant neoplasm of prostate	RAG1 HIF1A ATR CHD1 GHR IGFBP3 EGF GSTK1 INTS4 GREB1 ALOX5	6.95e-04	616	164	11	C0376358
Disease	Malignant Neoplasms	ATR RET BIRC6 LIN28A KIT	7.61e-04	128	164	5	C0006826
Disease	myeloid white cell count	ATP13A1 SLC6A17 VPS8 MECOM DIP2A SLC39A12 EGF CD33 SYN2 KIAA1755 HTR3D KIT RASAL2 HTT	7.79e-04	937	164	14	EFO_0007988
Disease	complex trait	KPNA4 IP6K1 CABLES1 ADO ABCB11 KIAA1755 LTBP1	8.34e-04	271	164	7	EFO_0010578
Disease	Cholestasis of pregnancy	ABCB4 ABCB11	8.41e-04	8	164	2	C0268318
Disease	Unilateral agenesis of kidney	FRAS1 RET	8.41e-04	8	164	2	C0266294
Disease	sporadic amyotrophic lateral sclerosis, survival time	SLC9A9 IDE	8.41e-04	8	164	2	EFO_0000714, EFO_0001357
Disease	Primary sclerosing cholangitis	HIF1A ABCB4	8.41e-04	8	164	2	C0566602
Disease	platelet crit	KALRN ATP13A1 MECOM CABLES1 SH3BP4 CDC7 SENP1 ADO KANSL1 EGF CD33 SYN2 KIT RASAL2	9.07e-04	952	164	14	EFO_0007985
Disease	retinal detachment, retinal break	FRAS1 SMYD1 FAT3	9.68e-04	35	164	3	EFO_0005773, EFO_0010698
Disease	osteoarthritis (is_marker_for)	HIF1A IGFBP3 EPAS1	9.68e-04	35	164	3	DOID:8398 (is_marker_for)
Disease	cystic fibrosis (implicated_via_orthology)	ABCB4 ABCB11	1.08e-03	9	164	2	DOID:1485 (implicated_via_orthology)
Disease	Adult Hepatocellular Carcinoma	TSC1 EGF	1.08e-03	9	164	2	C0279607
Disease	lifestyle measurement, systolic blood pressure	SLC9A9 KALRN	1.08e-03	9	164	2	EFO_0006335, EFO_0010724
Disease	cholestasis (implicated_via_orthology)	ABCB4 ABCB11	1.08e-03	9	164	2	DOID:13580 (implicated_via_orthology)
Disease	neuroimaging measurement, brain volume measurement	ATR FAT3 RGPD1 NCKAP5 SLC39A12 IGFBP3 KANSL1	1.14e-03	286	164	7	EFO_0004346, EFO_0006930
Disease	vesicular integral-membrane protein VIP36 measurement	KALRN NLK	1.34e-03	10	164	2	EFO_0022012
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TSC1 ZNF804A MERTK ALOX5 EPAS1	1.46e-03	148	164	5	C0279702
Disease	osteoarthritis, knee, body mass index	B4GALNT4 ABHD16B LTBP1	1.54e-03	41	164	3	EFO_0004340, EFO_0004616
Disease	age at menopause	PITPNM2 BIRC6 OPA1 TASOR2 CHUK VPS9D1 KPNA3	1.56e-03	302	164	7	EFO_0004704
Disease	mean reticulocyte volume	ATR CHD1 URB2 TRIM10 ABCB4 DIP2A ZNF469 NOD1 KANSL1 SYN2 INTS4 EPAS1	1.77e-03	799	164	12	EFO_0010701
Disease	hepatocyte growth factor measurement	OTUD7A CAMSAP2 HTT	1.89e-03	44	164	3	EFO_0006903
Disease	psoriasis (is_marker_for)	HIF1A IL3 EPAS1	1.89e-03	44	164	3	DOID:8893 (is_marker_for)
Disease	bronchopulmonary dysplasia (biomarker_via_orthology)	HIF1A EPAS1	1.95e-03	12	164	2	DOID:11650 (biomarker_via_orthology)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	SMYD1 MECOM ABCB4 SLC39A12 SYN2 ABCB11	2.26e-03	239	164	6	EFO_0010934
Disease	Skin Abnormalities	CHUK ZNF469	2.30e-03	13	164	2	C0037268
Disease	pancreatic cancer (is_marker_for)	RET EGF IL3 ALOX5	2.47e-03	101	164	4	DOID:1793 (is_marker_for)
Disease	leprosy	KALRN NOD2 ADO KANSL1	2.65e-03	103	164	4	EFO_0001054
Disease	Testicular Germ Cell Tumor	KIT ALOX5	2.67e-03	14	164	2	C1336708
Disease	type 2 diabetes mellitus (implicated_via_orthology)	IDE ALMS1 ACOT2 G6PC1	2.84e-03	105	164	4	DOID:9352 (implicated_via_orthology)
Disease	sitting height ratio	MECOM CABLES1 IGFBP3	2.89e-03	51	164	3	EFO_0007118
Disease	Glioblastoma Multiforme	HIF1A FAT1 EGF NLK	3.47e-03	111	164	4	C1621958
Disease	Autistic Disorder	SLC9A9 NBEA TSC1 GHR IGFBP3 EGF	3.49e-03	261	164	6	C0004352
Disease	Dermatitis	NOD2 EGF	3.50e-03	16	164	2	C0011603
Disease	obsolete_red blood cell distribution width	ATR KALRN SUN1 RGPD1 MECOM AP3B1 BIRC6 TRIM10 ABCB4 KANSL1 CD33 SIMC1 ERMAP SYN2 ABCB11 PYCR3	3.53e-03	1347	164	16	EFO_0005192
Disease	pneumonia, COVID-19	WDR19 TYRP1 FAT1 VPS13B	3.70e-03	113	164	4	EFO_0003106, MONDO_0100096
Disease	cognitive function measurement, self reported educational attainment	BTAF1 BIRC6 ZNF804A PRR12 KANSL1 ALMS1 CNTNAP4	3.83e-03	355	164	7	EFO_0004784, EFO_0008354
Disease	Glycogen storage disease	PHKA1 G6PC1	3.95e-03	17	164	2	cv:C0017919
Disease	alcohol consumption measurement	NBEA NCKAP5 BIRC6 ZNF804A GARIN2 WDR19 TYRP1 SLC39A12 KANSL1 ALMS1 SCAF11 WDR90 ANKRD36 KIT HTT	4.03e-03	1242	164	15	EFO_0007878
Disease	prostate cancer (is_implicated_in)	HIF1A CHD1 CHUK IGFBP3	4.19e-03	117	164	4	DOID:10283 (is_implicated_in)
Disease	hearing threshold measurement, hearing measurement	AP3B1 GRAMD2B RASAL2	4.79e-03	61	164	3	EFO_0007616, EFO_0007618
Disease	Chronic myeloproliferative disorder	ATR KIT	4.93e-03	19	164	2	C1292778
Disease	kidney failure (biomarker_via_orthology)	HIF1A PHEX	4.93e-03	19	164	2	DOID:1074 (biomarker_via_orthology)
Disease	polycystic kidney disease (biomarker_via_orthology)	HIF1A EPAS1	4.93e-03	19	164	2	DOID:0080322 (biomarker_via_orthology)
Disease	fasting blood glucose measurement	FAT3 SNX33 MTPN SLC39A12 CNTNAP4 ABCB11	5.51e-03	287	164	6	EFO_0004465

Protein segments in the cluster

Peptide	Gene	Start	Entry
AFSILLTVPLDHLKP	URB2	1346	Q14146
ESVVLIPKSLHHVPD	C2orf16	331	Q68DN1
LHLPPLKIVTIHECD	CBARP	171	Q8N350
LPLPHSVSSHLDKAS	EPAS1	41	Q99814
DISTHSLILHDLIPP	BIRC6	1836	Q9NR09
LASTPFHKLPVESVH	BUB1	606	O43683
LVHLKVAALGSDPHI	BTN1A1	136	Q13410
FLLKSGTSIPLHDHP	ADO	101	Q96SZ5
LHFIEKAHTLILQPP	ATP13A1	761	Q9HD20
PVIFAKIQLEHHISP	EHD2	336	Q9NZN4
VLSTPHSHREKPGIF	ALMS1	711	Q8TCU4
QVLPHSHPTEEALKI	ALMS1	1346	Q8TCU4
VQLSHVAPLKAALHP	CNTNAP4	1171	Q9C0A0
LVHEPPLAVVDHKST	ABCB11	706	O95342
LLPLHKVKSLSVYHP	PPP2R5C	251	Q13362
LSPHPHSVVLRSEFK	ACOT2	6	P49753
QPPLFTHTVKDRDHI	ANKRD36	481	A6QL64
AVLSVNHIKRPHSVP	ANKRD17	2201	O75179
TEPLILHLTPSHKAA	DENND1C	676	Q8IV53
DHKVKAPVHFVEPLS	CAMSAP1	1066	Q5T5Y3
SHEEELIPLHKSIPS	CHD1	1216	O14646
YHAKLLDPSTPVHIL	DCAF16	76	Q9NXF7
LVLIHPKPSHEAASS	ARR3	346	P36575
HLKNVEATHFSPLEP	ABHD16B	446	Q9H3Z7
STPAFVPTKTHVLLH	AP3B1	861	O00203
LSSAPDEIQHPHIKF	RAG1	11	P15918
IISHSSKVLHFPNPE	RAB3GAP1	811	Q15042
SAFLHLPLPEQIHKA	INTS4	806	Q96HW7
LIPQPTFTEKVAHEH	NUP107	776	P57740
SKVTHLLIKRPPFFH	NOX5	456	Q96PH1
FSTSHVPEELKQPLH	MECOM	1166	Q03112
GFHSPLIKHPEVKSA	CHRNA1	381	P02708
SEPHPHLDVLLFVEK	FAT1	3686	Q14517
HLSLISVPLLIYHPA	SLC10A7	296	Q0GE19
DVLSHFPNLLSHPKE	KPNA3	326	O00505
FHITLHPVDDSLPVV	FRAS1	2301	Q86XX4
EHHTLPEVKSFVLTP	FRAS1	3551	Q86XX4
IHHYTKVADLSPIPV	HOGA1	151	Q86XE5
FPLSLKNHDHPVLSV	GREB1	1826	Q4ZG55
IHPHTLFTPLLIGFV	KIT	516	P10721
LPPLAFKHTVGHIIL	MERTK	91	Q12866
LKALSHHVDPSQLPA	KIAA1755	691	Q5JYT7
KILIASPSPTHIHKE	HIF1A	636	Q16665
AKIISFLLPPDESLH	CHUK	321	O15111
DLLSHQKHLTVGLPP	PHKA1	846	P46020
VHVTDLTHRPKILIP	CD33	136	P20138
LSEKSHHISIPSPDI	IL17RE	131	Q8NFR9
PIQKATDSFHTELHP	DKKL1	151	Q9UK85
PVDIPLSTALHSKHQ	IBA57-DT	66	B1ANH7
PKLSHDANETLPLHL	PLXNB2	726	O15031
LPEHVLVKIFSFLPT	FBXO46	476	Q6PJ61
ELIPKPDTFHLTHDA	LRRC36	291	Q1X8D7
TIHLHPQFPVVIEKT	LTBP1	831	Q14766
LSKVARHFHSPPIIL	PDZD2	1711	O15018
ELHHIVLENPSFSPL	NLRP1	1201	Q9C000
HFPLHLTVPKFSLPE	GAREM1	296	Q9H706
PAAEIDHVIPLISKH	KALRN	1041	O60229
SVKLSALRPIVNHPH	DPY19L1	561	Q2PZI1
LHFLQPSHIEKPTFA	HEATR6	936	Q6AI08
LPPLHSITVHIYKDV	RASAL2	221	Q9UJF2
IIPSESHPHIQLLKS	NOD1	11	Q9Y239
HHIRFKLAPPSSTLS	KANSL1	16	Q7Z3B3
IPLTDSEHKLLPLHF	OTUD7A	386	Q8TE49
SEHKLLPLHFAVDPG	OTUD7A	391	Q8TE49
LHKIIVSPQPLSSDH	NLK	226	Q9UBE8
AAPPSKIHVLLLVLH	PITPNM2	416	Q9BZ72
FSRSLKPVLPHKVAH	LIG3	526	P49916
VAIALTHHPRLPAAI	HCN4	791	Q9Y3Q4
APTLVVLHETFPKHT	MFSD14A	56	Q96MC6
KAANIHPFIETLPHK	ABCB4	1156	P21439
PVKVTLSEGPHHVAL	OPA1	326	O60313
PIDPLFKHFHSVDIQ	RGPD3	626	A6NKT7
PLIHIQPKETAAIFH	ATR	1221	Q13535
THAIPALQPIVHDLF	HTT	1536	P42858
LATAAPTRHPIHIKD	IL3	106	P08700
SPHTAVKDFVIIPLH	DNASE1L3	141	Q13609
HPALVLTPQHPEFKT	BTAF1	1581	O14981
PVLVALEFALHLPEH	CABLES1	606	Q8TDN4
ALKESHIHLPTEQPE	C18orf15	6	Q96N68
LFDVKPGTLEISPHH	CPLANE1	2341	Q9H799
VAPHIKVESHIQPSL	GHR	546	P10912
HSSFVPLGELKVVHP	EGF	286	P01133
HLIPTSHPIRIAAEL	CDC7	91	O00311
ASLVLLHVFDSLKPP	G6PC1	301	P35575
HSIVTSFLPHELPLL	POLQ	2006	O75417
HLQIPIHFPKDFLSV	GSTK1	76	Q9Y2Q3
IHVVTHVPFSLEKEP	FAT3	266	Q8TDW7
PSLESFHPLNIHIGK	GON4L	106	Q3T8J9
HLKSPTLSQVHSPLV	BCL9L	931	Q86UU0
VFNTEAHPLPVLHLA	MAN1A2	616	O60476
EDFHIVKLPLLPHEV	GET3	311	O43681
SPKVELHSHSEVPFQ	IP6K1	151	Q92551
VLEIHSHFPHKPIIL	KANSL3	336	Q9P2N6
EDTLIEHAHTKPLLP	IDE	746	P14735
EHAHTKPLLPSQLVR	IDE	751	P14735
HTTPDHPLFLLLNAK	DIP2A	996	Q14689
HFHKLFLSVPTEEPL	GRAMD2B	111	Q96HH9
SLSLLHHPLPVEESL	GPR21	86	Q99679
EEHHQSLKALVLPSP	LIG1	806	P18858
HPRSTELPKTHIEQI	SCAF11	691	Q99590
PPHNHSRSLIKTLLE	SLC39A12	56	Q504Y0
ALQIIHDTEKSPHTP	CAMSAP2	556	Q08AD1
PIDPLFKHFHSVDIQ	RGPD1	616	P0DJD0
SDPKFHPLHSKIIII	IGFBP3	161	P17936
LIILAISSDPHLHTP	OR1N2	61	Q8NGR9
HFVAVTLDPDTAHPK	ERMAP	236	Q96PL5
HIKSPSNFLKLVPHL	GARIN2	401	Q8N9W8
LPTFPVVVKIGHAHS	SYN2	261	Q92777
PIDPLFKHFHSVDIQ	RGPD4	626	Q7Z3J3
SVLLPEKFLTHTHGL	SUSD2	581	Q9UGT4
SPRILATHLHYDKLP	SULT6B1	111	Q6IMI4
ALHKHSNALVDVLPP	PSMC4	131	P43686
IPHTSEHTPVFIKLP	RNF152	81	Q8N8N0
PVTVLAIFHELHVDP	SLC9A9	216	Q8IVB4
PKHIHPSFKTVVTIF	SH3BP4	481	Q9P0V3
VPETLHLNPSLKHTL	SKIL	76	P12757
QLPAVHPIFKLLVAH	ALOX5	386	P09917
LFELRSDPHIPKHSA	NCKAP5	856	O14513
HSPDRPLVLTVEHKE	PIWIL2	196	Q8TC59
PQLLPLLKHTTSYLH	TAF2	271	Q6P1X5
PIFSHPVLQERLHTK	SLC26A5	21	P58743
SIPHPSLNHGFLAKL	NBEA	1616	Q8NFP9
LLHLHEKFFRPLPES	PNLDC1	261	Q8NA58
SPFDPAHKHTAVLVD	SEMA4A	176	Q9H3S1
AILLVTHGPSHPITK	SMYD1	421	Q8NB12
FTIAKPTTHFPLHLS	SENP1	206	Q9P0U3
RLLHKFTVISVPHLP	SNX33	276	Q8WV41
PVHHLFFQTLIPDKD	SIMC1	441	Q8NDZ2
KVSPDVPVLLNVLHH	OR56A3	271	Q8NH54
HPPGTAILHIKFTDD	VPS8	241	Q8N3P4
LHSKPELKDHPITQF	VPS8	301	Q8N3P4
GDLLPHVSSPKIHLQ	WDR19	886	Q8NEZ3
GLLSPHDVLHLKPSQ	PRR12	181	Q9ULL5
HQIAGTFVLIPPHSK	REELD1	91	A0A1B0GV85
KSHILPHPVVVADLL	URB1	2126	O60287
LVIFATKPHVLPAVL	PYCR3	71	Q53H96
FITHLLHVATTQPLP	HTR3D	326	Q70Z44
LHFPLFPHTRTTVKK	B4GALNT4	141	Q76KP1
IISLHFPFNPDLHKV	RNF213	386	Q63HN8
THLSPNDPIFVLLHT	TYRP1	391	P17643
PALHILTTLQEPHDK	TSC1	56	Q92574
FRPLPSKHFVIHLDV	WDR90	76	Q96KV7
KLSIPHTHLLATLDP	WDR88	46	Q6ZMY6
HFFPLQSTLGLIKPH	NME8	446	Q8N427
INAPDKHHITPLLSA	MTPN	61	P58546
LILQHFLLHATPPDS	NOD2	516	Q9HC29
TPLLFHPHTKGSQIL	NEURL1	61	O76050
SELLHTPAHVLPSAA	WDR75	731	Q8IWA0
NKVFPSPHILQIHLS	ZBTB18	376	Q99592
KSLHPLLAPFLEAHV	SNX21	316	Q969T3
SSPLHNHTLFPEKQI	ZNF281	696	Q9Y2X9
ADAKPLLHILRHSPF	PHEX	151	P78562
KHLVHILPRPSSLSA	USF3	631	Q68DE3
FLPVLKPHLEHLVAD	PSME4	1356	Q14997
LLPLPHHFGTVKSEV	RALGAPB	621	Q86X10
PIKIIAVHPHFVRSS	VPS41	126	P49754
LHFNVSVLPVSLHLP	RET	391	P07949
VLEHFLTFLPKPSLV	ZNF200	46	P98182
VAHLLNSITEPAPKH	ZNF469	3196	Q96JG9
KSIKHQLGLSFLPHP	ZNF415	181	Q09FC8
HISLDPQTSHPKLLL	TRIM10	311	Q9UDY6
SHLPDPIIIHLEKRS	VPS13B	2851	Q7Z7G8
PFITVVSPKSPHLHK	ZGRF1	871	Q86YA3
DLIPPHVNFSHLTTK	SLC6A17	386	Q9H1V8
HLHQIPSLLKLKHFP	TASOR2	2241	Q5VWN6
IHPAAFTLEHIPKTL	SUN1	686	O94901
ELKPLVHSPHAIVVR	WDR26	181	Q9H7D7
SLVSHLLSLPDHPIA	VPS9D1	271	Q9Y2B5
HLTLTFHSPEVPKIK	TMEM202	6	A6NGA9
PSLVIHLRIHTGEKP	ZNF449	476	Q6P9G9
ILSDIRKPPDHVFHS	TDH	81	Q8IZJ6
PIKDQLGLSFHSHLP	ZNF816	151	Q0VGE8
HPDHLITENFPLKLC	VPS26C	281	O14972
KHTFDRPVEILIHPS	VWA5B1	266	Q5TIE3
IIPASVLHPSHLAFP	ZNF804A	1171	Q7Z570
DALSHFPALLTHPKE	KPNA4	326	O00629
LDPPVDVFVHQSKLH	LIN28A	66	Q9H9Z2
RPSVTHLLDHPFIKG	MYO3B	281	Q8WXR4
DHLLHAPEFIIKPRS	MYOM1	271	P52179
RLLALSHEHKFPTVP	MYOM1	1231	P52179