Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	CAPN3 BAG2 MYOZ2 APC ITPRID2 INO80 NEB CEP350 SPTBN5 KIF3B DST PDLIM1 AP1G1 KIF28P MICAL3 KIF3C UTRN GOLGA2	5.84e-06	1099	98	18	GO:0008092
GeneOntologyMolecularFunction	frizzled binding	WNT3 WNT8B WNT3A WNT16	5.29e-05	42	98	4	GO:0005109
GeneOntologyMolecularFunction	microtubule motor activity	KIF3B KIF28P KIF3C DNAH9	3.90e-04	70	98	4	GO:0003777
GeneOntologyMolecularFunction	actin binding	MYOZ2 ITPRID2 INO80 NEB SPTBN5 DST PDLIM1 MICAL3 UTRN	5.81e-04	479	98	9	GO:0003779
GeneOntologyBiologicalProcess	positive regulation of collateral sprouting in absence of injury	WNT3 WNT3A	2.19e-05	2	97	2	GO:0048697
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	USP34 WNT3 WNT8B APC BMP2 TLE2 WNT3A WNT16 LRP5	3.54e-05	344	97	9	GO:0060070
GeneOntologyCellularComponent	Wnt signalosome	WNT3 APC WNT3A LRP5	8.25e-07	16	99	4	GO:1990909
GeneOntologyCellularComponent	microtubule	BAG2 APC INO80 TEKT5 KIF3B DST KIF28P KIF3C DNAH9 GOLGA2	2.18e-04	533	99	10	GO:0005874
GeneOntologyCellularComponent	Wnt-Frizzled-LRP5/6 complex	WNT3A LRP5	2.20e-04	5	99	2	GO:1990851
GeneOntologyCellularComponent	mitotic cohesin complex	SMC1A SGO2	4.59e-04	7	99	2	GO:0030892
GeneOntologyCellularComponent	Z disc	CAPN3 MYOZ2 NEB DST PDLIM1	7.63e-04	151	99	5	GO:0030018
GeneOntologyCellularComponent	microtubule associated complex	SPTBN5 KIF3B KIF28P KIF3C DNAH9	1.02e-03	161	99	5	GO:0005875
GeneOntologyCellularComponent	I band	CAPN3 MYOZ2 NEB DST PDLIM1	1.17e-03	166	99	5	GO:0031674
GeneOntologyCellularComponent	cohesin complex	SMC1A SGO2	1.19e-03	11	99	2	GO:0008278
GeneOntologyCellularComponent	supramolecular fiber	CAPN3 BAG2 MYOZ2 APC INO80 NEB TEKT5 KIF3B DST PDLIM1 KIF28P KIF3C DNAH9 GOLGA2	1.30e-03	1179	99	14	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	CAPN3 BAG2 MYOZ2 APC INO80 NEB TEKT5 KIF3B DST PDLIM1 KIF28P KIF3C DNAH9 GOLGA2	1.39e-03	1187	99	14	GO:0099081
Domain	Wnt	WNT3 WNT8B WNT3A WNT16	2.50e-06	19	97	4	IPR005817
Domain	Wnt_CS	WNT3 WNT8B WNT3A WNT16	2.50e-06	19	97	4	IPR018161
Domain	wnt	WNT3 WNT8B WNT3A WNT16	2.50e-06	19	97	4	PF00110
Domain	WNT1	WNT3 WNT8B WNT3A WNT16	2.50e-06	19	97	4	SM00097
Domain	WNT1	WNT3 WNT8B WNT3A WNT16	2.50e-06	19	97	4	PS00246
Domain	Wnt3	WNT3 WNT3A	2.67e-05	2	97	2	IPR009141
Domain	Actinin_actin-bd_CS	SPTBN5 DST UTRN	2.23e-04	23	97	3	IPR001589
Domain	Spectrin	SPTBN5 DST UTRN	2.23e-04	23	97	3	PF00435
Domain	ACTININ_2	SPTBN5 DST UTRN	2.23e-04	23	97	3	PS00020
Domain	ACTININ_1	SPTBN5 DST UTRN	2.23e-04	23	97	3	PS00019
Domain	CH	SPTBN5 DST MICAL3 UTRN	3.63e-04	65	97	4	SM00033
Domain	Spectrin_repeat	SPTBN5 DST UTRN	4.50e-04	29	97	3	IPR002017
Domain	CH	SPTBN5 DST MICAL3 UTRN	4.82e-04	70	97	4	PF00307
Domain	-	SPTBN5 DST MICAL3 UTRN	5.09e-04	71	97	4	1.10.418.10
Domain	CH	SPTBN5 DST MICAL3 UTRN	5.66e-04	73	97	4	PS50021
Domain	Spectrin/alpha-actinin	SPTBN5 DST UTRN	6.04e-04	32	97	3	IPR018159
Domain	SPEC	SPTBN5 DST UTRN	6.04e-04	32	97	3	SM00150
Domain	CH-domain	SPTBN5 DST MICAL3 UTRN	6.27e-04	75	97	4	IPR001715
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT3 WNT8B APC WNT3A WNT16 LRP5	3.48e-08	37	74	6	M47411
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	WNT3 WNT8B APC WNT3A WNT16 LRP5	1.35e-07	46	74	6	M47409
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8B BMP2 WNT3A WNT16	3.74e-07	29	74	5	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8B BMP2 WNT3A WNT16	3.74e-07	29	74	5	M47377
Pathway	KEGG_BASAL_CELL_CARCINOMA	WNT3 WNT8B APC BMP2 WNT3A WNT16	4.03e-07	55	74	6	M17807
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION	WNT3 WNT8B WNT3A WNT16	2.55e-06	19	74	4	M47836
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	WNT3 APC WNT3A WNT16 LRP5	3.22e-06	44	74	5	MM15878
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT3 WNT8B APC WNT3A WNT16	3.61e-06	45	74	5	M47412
Pathway	WNT_SIGNALING	WNT3 APC TLE2 WNT3A WNT16 LRP5	7.01e-06	89	74	6	M5493
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT3 WNT8B WNT3A WNT16	8.14e-06	25	74	4	MM14940
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT3 WNT8B WNT3A WNT16	9.58e-06	26	74	4	M27239
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8B BMP2 WNT3A WNT16	1.08e-05	56	74	5	M1053
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR	WNT3 WNT8B WNT3A WNT16	1.30e-05	28	74	4	M47835
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	USP34 WNT3 WNT8B APC TLE2 WNT3A LRP5	1.87e-05	158	74	7	MM14791
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	WNT8B APC WNT3A LRP5	1.98e-05	31	74	4	M27400
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	WNT8B APC WNT3A LRP5	1.98e-05	31	74	4	MM15154
Pathway	REACTOME_SIGNALING_BY_WNT	USP34 WNT3 WNT8B APC TLE2 WNT3A WNT16 LRP5	3.49e-05	239	74	8	MM14756
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	WNT3 WNT8B BMP2 WNT3A WNT16 LRP5	3.53e-05	118	74	6	M39852
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	WNT3 WNT3A WNT16 LRP5	3.63e-05	36	74	4	M39699
Pathway	WP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY	PDE1A WNT3 WNT8B WNT3A WNT16	8.22e-05	85	74	5	M48315
Pathway	WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA	WNT3 APC WNT3A WNT16 LRP5	1.02e-04	89	74	5	M39563
Pathway	KEGG_WNT_SIGNALING_PATHWAY	WNT3 WNT8B APC WNT3A WNT16 LRP5	1.39e-04	151	74	6	M19428
Pathway	WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER	WNT3 APC WNT3A WNT16 LRP5	1.62e-04	98	74	5	M39731
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	WNT3 APC WNT3A WNT16 LRP5	1.86e-04	101	74	5	M39387
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	WNT3 APC WNT3A WNT16 LRP5	1.86e-04	101	74	5	MM15829
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	USP34 WNT3 WNT8B APC TLE2 WNT3A LRP5	2.16e-04	233	74	7	M27099
Pathway	WP_WNT_SIGNALING	WNT3 APC WNT3A WNT16	2.91e-04	61	74	4	MM15893
Pathway	WP_WNT_SIGNALING_WP428	WNT3 APC WNT3A WNT16 LRP5	3.14e-04	113	74	5	M39669
Pathway	REACTOME_SIGNALING_BY_WNT	USP34 WNT3 WNT8B APC TLE2 WNT3A WNT16 LRP5	3.26e-04	330	74	8	M7847
Pathway	WP_WNTBETACATENIN_SIGNALING_IN_LEUKEMIA	ZBTB16 APC LRP5	3.31e-04	26	74	3	M39407
Pathway	WP_ESC_PLURIPOTENCY_PATHWAYS	WNT3 APC WNT3A WNT16 LRP5	3.55e-04	116	74	5	MM15863
Pathway	WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS	WNT3 APC WNT3A WNT16 LRP5	3.69e-04	117	74	5	M39530
Pathway	PID_WNT_SIGNALING_PATHWAY	WNT3 WNT3A LRP5	4.14e-04	28	74	3	M77
Pathway	REACTOME_RHO_GTPASE_CYCLE	FILIP1 TMEM59 SHMT2 ARHGAP11A DST ITSN2 TJP2 PAK3 GOLGA2	4.66e-04	439	74	9	MM15595
Pathway	WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME	SMC1A APC SGO2	7.39e-04	34	74	3	M42555
Pathway	REACTOME_SIGNALING_BY_WNT_IN_CANCER	APC WNT3A LRP5	7.39e-04	34	74	3	M27405
Pathway	REACTOME_SIGNALING_BY_RNF43_MUTANTS	WNT3A LRP5	7.46e-04	8	74	2	M27433
Pathway	BIOCARTA_ALK_PATHWAY	APC RFC1 BMP2	9.49e-04	37	74	3	M17400
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST ITSN2 PAK3	1.11e-03	39	74	3	MM15607
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST ITSN2 PAK3	1.19e-03	40	74	3	M41816
Pathway	WP_BREAST_CANCER_PATHWAY	WNT3 APC WNT3A WNT16 LRP5	1.28e-03	154	74	5	M39739
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	WNT3 WNT8B WNT3A WNT16	1.49e-03	94	74	4	M797
Pathway	KEGG_PATHWAYS_IN_CANCER	ZBTB16 WNT3 WNT8B APC BMP2 WNT3A WNT16	1.56e-03	325	74	7	M12868
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	WNT3 WNT8B WNT3A WNT16 LRP5	1.56e-03	161	74	5	M39770
Pathway	KEGG_MELANOGENESIS	WNT3 WNT8B WNT3A WNT16	1.95e-03	101	74	4	M7761
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	FILIP1 TMEM59 SHMT2 ARHGAP11A DST ITSN2 TJP2 PAK3 SGO2 GOLGA2	2.00e-03	649	74	10	MM15690
Pathway	WP_REGULATION_OF_SISTER_CHROMATID_SEPARATION_AT_THE_METAPHASEANAPHASE_TRANSITION	SMC1A APC	2.37e-03	14	74	2	M39772
Pathway	REACTOME_RHO_GTPASE_CYCLE	FILIP1 TMEM59 SHMT2 ARHGAP11A DST ITSN2 TJP2 PAK3	2.41e-03	450	74	8	M27078
Pathway	WP_WNT_SIGNALING_PATHWAY	WNT3 APC WNT3A LRP5	2.65e-03	110	74	4	MM15977
Pathway	WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT	WNT3 APC WNT3A WNT16	2.65e-03	110	74	4	M39492
Pathway	REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS	WNT3A LRP5	2.73e-03	15	74	2	M27273
Pubmed	A human MAP kinase interactome.	APC CRTC1 ITPRID2 NEB CEP350 GTF2A1 USF3 DST RASAL3 CSN1S1 ITSN2 PAK3 BICRAL GOLGA2	1.33e-10	486	100	14	20936779
Pubmed	Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.	WNT3 WNT8B APOB WNT3A WNT16 LRP5	6.14e-09	49	100	6	19562671
Pubmed	Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.	WNT3 WNT8B APC TLE2 WNT3A WNT16 LRP5	8.07e-09	90	100	7	19515997
Pubmed	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.	WNT3 WNT8B APC WNT3A WNT16	5.38e-08	35	100	5	23376422
Pubmed	Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.	WNT3 WNT8B WNT3A WNT16 LRP5	7.20e-08	37	100	5	15342465
Pubmed	Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.	WNT3 WNT8B BMP2 WNT3A WNT16	8.27e-08	38	100	5	23190887
Pubmed	Wnt family proteins are secreted and associated with the cell surface.	WNT3 WNT8B WNT3A WNT16	1.49e-07	17	100	4	8167409
Pubmed	Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.	WNT3 APC WNT3A	2.30e-07	5	100	3	18716223
Pubmed	Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.	WNT3 WNT8B WNT3A WNT16	2.41e-07	19	100	4	11520664
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	IPO5 ZNF211 DST ZNF197 BICRAL KIF3C UTRN	2.89e-07	151	100	7	17043677
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT3 WNT8B WNT3A WNT16	3.71e-07	21	100	4	11914369
Pubmed	Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.	WNT3 WNT8B WNT3A WNT16	3.71e-07	21	100	4	31914354
Pubmed	Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration.	WNT3 WNT8B WNT3A WNT16	4.52e-07	22	100	4	18991257
Pubmed	Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.	WNT3 WNT8B WNT3A WNT16	5.46e-07	23	100	4	27362799
Pubmed	Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype.	BMP2 WNT3A LRP5	8.01e-07	7	100	3	24006258
Pubmed	Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.	WNT3 WNT8B WNT3A WNT16	1.25e-06	28	100	4	20940229
Pubmed	Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.	WNT3 WNT8B WNT3A WNT16	1.25e-06	28	100	4	24394376
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	WNT3 WNT8B WNT3A WNT16	1.45e-06	29	100	4	22956684
Pubmed	3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).	WNT3 WNT8B WNT3A WNT16	1.45e-06	29	100	4	18364260
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	WNT3 WNT8B WNT3A WNT16	1.66e-06	30	100	4	19282366
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	WNT3 WNT8B WNT3A WNT16	1.66e-06	30	100	4	21936019
Pubmed	Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.	WNT3 WNT8B WNT3A WNT16	1.66e-06	30	100	4	15880404
Pubmed	Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.	WNT3 WNT8B WNT3A WNT16	1.66e-06	30	100	4	36305473
Pubmed	Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3.	SEMA3C WNT3 BMP2 WNT3A	1.91e-06	31	100	4	25053429
Pubmed	Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2S252W/+ ) mouse model.	WNT3 WNT3A LRP5	2.73e-06	10	100	3	32822074
Pubmed	The regulation and deregulation of Wnt signaling by PARK genes in health and disease.	WNT3 APC LRP5	2.73e-06	10	100	3	24115276
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	WNT3 WNT8B WNT3A WNT16	3.15e-06	35	100	4	30940800
Pubmed	Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.	WNT3 WNT8B WNT3A WNT16	3.15e-06	35	100	4	19185060
Pubmed	Integrated analysis of Wnt signalling system component gene expression.	WNT3 WNT8B WNT3A WNT16	3.95e-06	37	100	4	35831952
Pubmed	Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.	WNT3 WNT3A WNT16 LRP5	3.95e-06	37	100	4	18800919
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	WNT3 WNT8B WNT3A WNT16	4.41e-06	38	100	4	21041481
Pubmed	Tissue-specific requirements of beta-catenin in external genitalia development.	WNT3 WNT8B WNT3A LRP5	4.41e-06	38	100	4	18635608
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 INO80 TEFM TJP2 DEPDC5 UTRN	4.42e-06	147	100	6	29576527
Pubmed	Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.	WNT3 WNT8B WNT3A WNT16	4.90e-06	39	100	4	24586192
Pubmed	Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.	WNT3 WNT3A WNT16	4.98e-06	12	100	3	15778975
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 UAP1 ZBTB16 APC CRTC1 ITPRID2 CEP350 DST MYLK3 ZNF286B TJP2 UTRN	7.02e-06	861	100	12	36931259
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	IPO5 SMC1A TMEM59 BAG2 SHMT2 ITPRID2 CEP350 DST PDLIM1 PKP3 CIZ1 TJP2 UTRN	7.73e-06	1024	100	13	24711643
Pubmed	Gpr177 regulates pulmonary vasculature development.	WNT3 WNT8B WNT3A WNT16	8.00e-06	44	100	4	23884445
Pubmed	Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cells.	BMP2 WNT3A	8.18e-06	2	100	2	22150562
Pubmed	PDLIM1 inhibits cell migration and invasion in diabetic retinopathy via negatively regulating Wnt3a.	PDLIM1 WNT3A	8.18e-06	2	100	2	37037887
Pubmed	Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45.	WNT3 WNT3A	8.18e-06	2	100	2	11788904
Pubmed	Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.	C1GALT1 GOLGA2	8.18e-06	2	100	2	30917363
Pubmed	Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK.	APC CRTC1	8.18e-06	2	100	2	23531613
Pubmed	Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.	WNT3 WNT3A	8.18e-06	2	100	2	2001840
Pubmed	Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblasts.	BMP2 WNT3A	8.18e-06	2	100	2	24867947
Pubmed	Plzf regulates germline progenitor self-renewal by opposing mTORC1.	ZBTB16 CRTC1	8.18e-06	2	100	2	20691905
Pubmed	Mesenchymal Stem Cells Within Gelatin/CaSO4 Scaffolds Treated Ex Vivo with Low Doses of BMP-2 and Wnt3a Increase Bone Regeneration.	BMP2 WNT3A	8.18e-06	2	100	2	26414873
Pubmed	INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.	APC INO80	8.18e-06	2	100	2	29383140
Pubmed	Associations between WNT signaling pathway-related gene polymorphisms and risks of osteoporosis development in Chinese postmenopausal women: a case-control study.	WNT16 LRP5	8.18e-06	2	100	2	34254535
Pubmed	Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling.	USP34 BMP2	8.18e-06	2	100	2	30181118
Pubmed	Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men.	WNT3A LRP5	8.18e-06	2	100	2	17137849
Pubmed	SAGE reveals expression of Wnt signalling pathway members during mouse prostate development.	WNT8B WNT3A LRP5	8.20e-06	14	100	3	16378759
Pubmed	Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.	WNT3 WNT8B WNT3A	1.02e-05	15	100	3	15044261
Pubmed	Expression patterns of Wnt genes in mouse gut development.	WNT3 WNT8B WNT3A	1.02e-05	15	100	3	11429295
Pubmed	Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.	WNT3 WNT8B WNT3A WNT16	1.04e-05	47	100	4	28813421
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	WNT3 WNT8B WNT3A WNT16	1.04e-05	47	100	4	33141892
Pubmed	Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.	WNT3 WNT8B WNT3A WNT16	1.04e-05	47	100	4	16678101
Pubmed	Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.	WNT3 WNT3A WNT16 LRP5	1.04e-05	47	100	4	18351675
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT3 WNT8B WNT3A	1.26e-05	16	100	3	10585256
Pubmed	The Wnts.	WNT3 WNT8B WNT3A	1.26e-05	16	100	3	9889131
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	IPO5 ZBTB16 SMC1A CAPN3 MYOZ2 NEB FAF1 DST UTRN	1.39e-05	497	100	9	23414517
Pubmed	Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J).	WNT8B BMP2 WNT3A	1.52e-05	17	100	3	10625551
Pubmed	Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.	WNT3 WNT8B WNT3A	1.52e-05	17	100	3	28733458
Pubmed	A physical interaction network of dengue virus and human proteins.	APOB DST GOLGA2	1.82e-05	18	100	3	21911577
Pubmed	Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.	WNT3A WNT16 LRP5	2.16e-05	19	100	3	21623369
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SEMA3C ZCCHC9 APC CRTC1 E4F1 ITPRID2 INO80 TEKT5 TEFM INTS10 DST AP1G1 ITSN2 CIZ1 UTRN	2.44e-05	1497	100	15	31527615
Pubmed	Salt-inducible kinase 1 regulates bone anabolism via the CRTC1-CREB-Id1 axis.	CRTC1 BMP2	2.45e-05	3	100	2	31672960
Pubmed	PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling.	BMP2 WNT3A	2.45e-05	3	100	2	20668165
Pubmed	Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.	KIF3B KIF3C	2.45e-05	3	100	2	26445448
Pubmed	Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.	KIF3B KIF3C	2.45e-05	3	100	2	27637334
Pubmed	Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.	WNT3 WNT3A	2.45e-05	3	100	2	26902720
Pubmed	Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APCmin mice.	APC PKP3	2.45e-05	3	100	2	34823217
Pubmed	APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex.	WNT3A LRP5	2.45e-05	3	100	2	20393562
Pubmed	Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.	KIF3B KIF3C	2.45e-05	3	100	2	11331403
Pubmed	Sequence and localization of a novel FK506-binding protein to mouse chromosome 11.	FKBP10 WNT3	2.45e-05	3	100	2	7507077
Pubmed	Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts.	BMP2 WNT3A	2.45e-05	3	100	2	16150699
Pubmed	Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression.	BMP2 WNT3A	2.45e-05	3	100	2	22213482
Pubmed	Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.	BMP2 WNT3A	2.45e-05	3	100	2	19139264
Pubmed	Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus.	IPO5 FAF1	2.45e-05	3	100	2	26811330
Pubmed	Wnt-3a and Wnt-3 differently stimulate proliferation and neurogenesis of spinal neural precursors and promote neurite outgrowth by canonical signaling.	WNT3 WNT3A	2.45e-05	3	100	2	20722074
Pubmed	Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts.	BMP2 WNT3A	2.45e-05	3	100	2	23032104
Pubmed	Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation.	FAF1 WNT3A	2.45e-05	3	100	2	21411632
Pubmed	Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.	WNT3 WNT16	2.45e-05	3	100	2	27630294
Pubmed	Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2.	BMP2 LRP5	2.45e-05	3	100	2	27802170
Pubmed	More severe phenotype of early-onset osteoporosis associated with recessive form of LRP5 and combination with DKK1 or WNT3A.	WNT3A LRP5	2.45e-05	3	100	2	33939331
Pubmed	Kinesin-2 and photoreceptor cell death: requirement of motor subunits.	KIF3B KIF3C	2.45e-05	3	100	2	16337628
Pubmed	Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.	WNT3A LRP5	2.45e-05	3	100	2	30664649
Pubmed	Crystal structure of a mammalian Wnt-frizzled complex.	WNT3 WNT3A	2.45e-05	3	100	2	31036956
Pubmed	Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.	WNT3 LRP5	2.45e-05	3	100	2	15699046
Pubmed	A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis.	WNT3 APC WNT3A	2.54e-05	20	100	3	22234613
Pubmed	Motor neurons with axial muscle projections specified by Wnt4/5 signaling.	WNT3 WNT8B WNT3A	3.41e-05	22	100	3	19285468
Pubmed	Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.	WNT3 WNT8B WNT3A	3.41e-05	22	100	3	12815618
Pubmed	Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.	WNT3 WNT3A LRP5	3.41e-05	22	100	3	17064353
Pubmed	Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization.	WNT8B DMBX1 WNT3A	4.47e-05	24	100	3	20816794
Pubmed	Differential activity of Wnt/beta-catenin signaling in the embryonic mouse thalamus.	WNT3 WNT8B WNT3A	4.47e-05	24	100	3	19924825
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	SMC1A BAG2 APC MIPOL1 DST CEP72 TJP2 UTRN	4.57e-05	446	100	8	24255178
Pubmed	Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.	WNT3 WNT3A	4.89e-05	4	100	2	15950605
Pubmed	Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.	WNT3A LRP5	4.89e-05	4	100	2	29176883
Pubmed	An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling.	WNT3 LRP5	4.89e-05	4	100	2	18044981
Pubmed	Proteins implicated in muscular dystrophy and cancer are functional constituents of the centrosome.	CAPN3 UTRN	4.89e-05	4	100	2	35790299
Interaction	FZD1 interactions	WNT3 WNT3A LRP5 GOLGA2	1.93e-06	19	98	4	int:FZD1
Interaction	STRN4 interactions	FILIP1 ZNF211 APC SHMT2 TLE2 TJP2 GOLGA2	1.43e-05	162	98	7	int:STRN4
Interaction	NCKAP5 interactions	APC CEP350 KIF3B KIF3C	1.70e-05	32	98	4	int:NCKAP5
Interaction	ZUP1 interactions	IPO5 SHMT2 INO80 TEFM TJP2 DEPDC5 UTRN	2.27e-05	174	98	7	int:ZUP1
GeneFamily	Wnt family\|Endogenous ligands	WNT3 WNT8B WNT3A WNT16	6.80e-07	19	68	4	360
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF3B KIF28P KIF3C	6.88e-04	46	68	3	622
ToppCell	RV\|World / Chamber and Cluster_Paper	PDE1A ZBTB16 MYOZ2 GBX1 MYLK3 MICAL3	3.40e-06	181	100	6	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	facs-Skin-Telogen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C UAP1 ZBTB16 DST PKP3 UTRN	5.06e-06	194	100	6	4d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCell	facs-Skin-Telogen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C UAP1 ZBTB16 DST PKP3 UTRN	5.06e-06	194	100	6	ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCell	facs-Skin-Telogen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C UAP1 ZBTB16 DST PKP3 UTRN	5.06e-06	194	100	6	bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TET2 RFC1 CEP350 DST ITSN2 UTRN	5.86e-06	199	100	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Cbln4_(Neuron.Slc17a7.Cbln4)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PADI4 DMBX1 SPTBN5 WNT3A	3.04e-05	79	100	4	d24301b6694f64e8bb1b5f0673f653d25d45d3eb
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Cbln4_(Neuron.Slc17a7.Cbln4)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PADI4 DMBX1 SPTBN5 WNT3A	3.04e-05	79	100	4	397f3a1f5fa67dd0b2ed53ebcad74dedf0498fce
ToppCell	droplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 GPR179 KIF3B SGO2 PABPC1L	3.06e-05	160	100	5	984990be02642a562f0c60ea99c01f005e7c02c2
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARPP21 CAPN3 ARHGAP11A RASAL3 SGO2	4.09e-05	170	100	5	2d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SEMA3C FAT4 PDE1A WNT3 DST	4.09e-05	170	100	5	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	390C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FKBP10 TTC24 ASAH2 BAG2 BICRAL	4.21e-05	171	100	5	70963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell	COVID-mDC1-\|COVID / Condition, Cell_class and T cell subcluster	SEMA3C PADI4 CAPN3 SPTBN5 GRAMD2A	4.70e-05	175	100	5	83a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCell	COVID-mDC1\|COVID / Condition, Cell_class and T cell subcluster	SEMA3C PADI4 CAPN3 SPTBN5 GRAMD2A	4.70e-05	175	100	5	b9280444016e21c28131a61df65cc5c56d402412
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZBTB16 NEXMIF RFX6 PDLIM1 RBM47	5.80e-05	183	100	5	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	RANBP6 SNX25 CARF MICAL3 JHY	5.96e-05	184	100	5	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	droplet-Thymus\|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARPP21 WNT8B CAPN3 RASAL3 PDLIM1	6.11e-05	185	100	5	83a78d17ad59503a694c1250082c4d8ae74d63e1
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	RANBP6 SNX25 CARF MICAL3 JHY	6.11e-05	185	100	5	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FKBP10 PDE1A ZBTB16 SCUBE1 RTL9	6.27e-05	186	100	5	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3C C1GALT1 DMBX1 PDLIM1 PABPC1L	6.59e-05	188	100	5	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 SEMA3C BAG2 SGCZ PAK3	6.93e-05	190	100	5	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 SEMA3C BAG2 SGCZ PAK3	6.93e-05	190	100	5	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	FILIP1 MYOZ2 DST MYLK3 MICAL3	6.93e-05	190	100	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	FILIP1 MYOZ2 GBX1 DST MYLK3	7.11e-05	191	100	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB16 BMP2 SGCZ TLE2 UTRN	7.11e-05	191	100	5	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE1A RFX6 ARHGAP11A SGO2 RBM47	7.28e-05	192	100	5	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 SMC1A CEP350 USF3 UTRN	7.46e-05	193	100	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 FILIP1 ZBTB16 SUCO UTRN	7.65e-05	194	100	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	FILIP1 MYOZ2 DST MYLK3 MICAL3	7.83e-05	195	100	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FKBP10 PDE1A BMP2 SCUBE1 PDLIM1	8.62e-05	199	100	5	ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 FAT4 ITPRID2 DST UTRN	8.83e-05	200	100	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	proximal-mesenchymal-Fibromyocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FKBP10 SEMA3C FAT4 BAG2 SCUBE1	8.83e-05	200	100	5	37d9f46f727a31e8e94e348e4ddd71a2125ba01a
ToppCell	proximal-3-mesenchymal-Fibromyocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FKBP10 SEMA3C FAT4 BAG2 SCUBE1	8.83e-05	200	100	5	ed6fbe61a04d29b105054f7058abe7469314b304
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 USP34 CEP350 ITSN2 UTRN	8.83e-05	200	100	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 ITPRID2 DST PDLIM1 ITSN2	8.83e-05	200	100	5	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	proximal-mesenchymal-Fibromyocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FKBP10 SEMA3C FAT4 BAG2 SCUBE1	8.83e-05	200	100	5	49658e1b530de0dad16d45a1112bdf5329bb800d
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NEB CEP350 DST UTRN	1.02e-04	49	54	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Disease	forced expiratory volume	TET2 FILIP1 ZBTB16 WNT3 RFX6 C1GALT1 INO80 FAF1 KIF3B DST CEP72 LRP5 MICAL3	1.33e-06	789	94	13	EFO_0004314
Disease	X-24307 measurement	RASAL3 DNAH9	1.00e-05	2	94	2	EFO_0800871
Disease	FEV/FEC ratio	TET2 USP34 CRTC1 RFX6 C1GALT1 NEB TEKT5 FAF1 SPTBN5 KIF3B DST CEP72 WNT16 MICAL3	3.38e-05	1228	94	14	EFO_0004713
Disease	chordin-like protein 1 measurement	RTL9 PAK3	9.98e-05	5	94	2	EFO_0020257
Disease	esophageal adenocarcinoma, Barrett's esophagus	CRTC1 APOB CEP72	1.32e-04	31	94	3	EFO_0000280, EFO_0000478
Disease	coronary artery disease	TET2 SEMA3C FAT4 PDE1A WNT3 C1GALT1 APOB INO80 SGCZ SCUBE1 CARF RBM47	4.09e-04	1194	94	12	EFO_0001645
Disease	Acute Promyelocytic Leukemia	TET2 ZBTB16 SMC1A	4.30e-04	46	94	3	C0023487
Disease	vital capacity	TET2 USP34 FILIP1 ZBTB16 IQCH WNT3 APOB INO80 DST RTL9 MICAL3 UTRN	5.56e-04	1236	94	12	EFO_0004312
Disease	esophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement	CRTC1 CEP72	7.65e-04	13	94	2	EFO_0000280, EFO_0000478, EFO_0008343
Disease	gallbladder cancer (is_implicated_in)	APC APOB	7.65e-04	13	94	2	DOID:3121 (is_implicated_in)
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	KIF28P LRP5	8.91e-04	14	94	2	DOID:898 (implicated_via_orthology)
Disease	gestational age	ZBTB16 FAF1 WNT3A UTRN	1.01e-03	138	94	4	EFO_0005112
Disease	peak expiratory flow	TET2 C1GALT1 TEKT5 FAF1 DST LRP5 MICAL3	1.08e-03	498	94	7	EFO_0009718
Disease	atrial fibrillation	USP34 FILIP1 WNT3 E4F1 FAF1 KIF3C	1.22e-03	371	94	6	EFO_0000275
Disease	Lipidemias	APC APOB	1.32e-03	17	94	2	C1706412
Disease	Hyperlipidemia	APC APOB	1.32e-03	17	94	2	C0020473
Disease	red blood cell density measurement	TET2 SEMA3C ZBTB16 CRTC1 INO80 RFC1 MIPOL1 DST TJP2	1.99e-03	880	94	9	EFO_0007978
Disease	muscular dystrophy (implicated_via_orthology)	SGCZ UTRN	2.03e-03	21	94	2	DOID:9884 (implicated_via_orthology)
Disease	beverage consumption measurement	ZNF143 ARPP21 ITSN2	2.39e-03	83	94	3	EFO_0010088
Disease	age at menarche	TET2 USP34 IQCH CRTC1 INO80 DST JHY	2.93e-03	594	94	7	EFO_0004703
Disease	white matter integrity, age at assessment	WNT3 CARF	3.10e-03	26	94	2	EFO_0004641, EFO_0008007

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQSIQNMRGNSHCVD	AGAP11	331	Q8TF27
EIVNGNMENSFSINH	FAT4	2706	Q6V0I7
NHMNQEGRAVIRGSN	A4GNT	291	Q9UNA3
SRLAEQQQQHAREMS	CEP72	486	Q9P209
QMQDALGNNSSFHHR	BMP2	156	P12643
NSSIDKEDNQQNRMH	ARPP21	256	Q9UBL0
QMDQPQDRNQALGTH	RASAL3	871	Q86YV0
REDAVHAMNNLNGTE	RBM47	291	A0AV96
LQAQDSHNMQFLNTG	RFX6	761	Q8HWS3
HIADFNTQQNMQLGR	IQCH	466	Q86VS3
RNHDEMSFNSGDIIQ	ITSN2	771	Q9NZM3
RMAIRAQHSNAAQTQ	SHMT2	21	P34897
TVDQQAMDRAHRLGQ	INO80	1201	Q9ULG1
IENQHQGAQDTSDLM	INTS10	216	Q9NVR2
NHKGSAMQDLAEVNN	AP1G1	801	O43747
RQMHQALQDFLSAQQ	PADI4	441	Q9UM07
QIHHQTRQNMAELQG	DEPDC5	631	O75140
LRMNSNNRDSSALNH	PAK3	16	O75914
SFLQIGRNMHQGNQT	OR1S1	6	Q8NH92
GRNMHQGNQTTITEF	OR1S1	11	Q8NH92
SSEAGNQRLQQVMHA	MICAL3	1016	Q7RTP6
EASGKAAQMAREQNH	JHY	91	Q6NUN7
ESLQNQQNAHTSRML	GPR179	1151	Q6PRD1
NGQRHAAEIANMSLD	GUCY2D	941	Q02846
NQTSANNMRHLTAEN	MIPOL1	291	Q8TD10
QHFGMVELLNNTANS	DST	5006	Q03001
SMNNSNHLVNSDNVG	ASAH2	306	Q9NR71
HSSRQDGLNDCMHNN	LRP5	896	O75197
MEQSNDSLRVNHNDG	CARF	1	Q8N187
AAHAQEQIRRMNENS	CSN1S1	116	P47710
NLGNQTRAVGSTHMN	KIF3C	196	O14782
LVRAMQQDAAQHGAR	MYLK3	96	Q32MK0
DMSGHFQQIKNIRNS	PDE1A	331	P54750
MENLKNHDNNLTQSG	PLEKHA8	276	Q96JA3
ETHEAAQQAINTMNG	PABPC1L	146	Q4VXU2
EDQGNQRVQAHAAAA	IPO5	451	O00410
AASQNHDADNVPNLM	GOLGA2	101	Q08379
LNHLQVQESLQAMGS	ITPRID2	521	P28290
HSIQNSQDMRQISDG	BAG2	61	O95816
AASGQNRMTQGQHFL	VENTXP1	16	P0C5K6
NFSAGNNENIMEAHV	APOB	3101	P04114
NRFAVRSQHQQMEQG	GBX1	346	Q14549
TIGDMFQNQDRNQDG	FKBP10	546	Q96AY3
QVASEHVMLNRNSSN	BICRAL	436	Q6AI39
QQMAARQANALSHQL	CRTC1	491	Q6UUV9
RQANALSHQLEQFNM	CRTC1	496	Q6UUV9
LQEQFRQHMAATNNL	DMBX1	266	Q8NFW5
GSENNLKLSVNNMAH	CEP350	231	Q5VT06
ERQSDQDMNHSPNIQ	CEP350	2331	Q5VT06
SDDNGQNHLEGQMNF	C1GALT1	51	Q9NS00
QNHLEGQMNFNADSS	C1GALT1	56	Q9NS00
SRENLLHQAMQNSGI	E4F1	366	Q66K89
RGNALSQQVQQMHEE	DNAH9	471	Q9NYC9
SHAGALQESLNQNFM	FAF1	181	Q9UNN5
RSEATEEGGNQQMHR	GRAMD2A	6	Q8IUY3
EMRNAVNDAGFHLNN	CAPN3	746	P20807
DNQHTCIHRSNEGMN	SCUBE1	151	Q8IWY4
AIENQGRNQEHQVMF	KIF28P	141	B7ZC32
ENTSNMTHLEAQNRI	PDLIM1	56	O00151
AMGNELSSQQQTEEH	RTL9	1336	Q8NET4
TLMNHQNQLEIFDGN	UTRN	1646	P46939
HALMNQRQSSVTNVG	ARHGAP11A	611	Q6P4F7
HPNQTCDMARQQRAQ	RNF19B	246	Q6ZMZ0
DTRQQHQQGDESQKM	SEMA3C	711	Q99985
EMNAKLANQESHNRQ	FILIP1	316	Q7Z7B0
GANQDIRQVLHNLSM	RFC1	806	P35251
DMLQSLVGQQNARHG	SNX25	781	Q9H3E2
RQVQMEDGFTLNNHQ	NEXMIF	1121	Q5QGS0
INGHTNETNTEMQRN	SGO2	311	Q562F6
DNIKHSQNMRANSIQ	TEKT5	301	Q96M29
AQDGQHQVLSMNRNA	TEFM	266	Q96QE5
QSDRNVTVNARNHMG	SGCZ	106	Q96LD1
RTMENQGNQRVQSHA	RANBP6	456	O60518
DASMHQQQELQREGQ	SPTBN5	2731	Q9NRC6
HDDNRSDNFNTGNMT	APC	806	P25054
QHQQRLGEIQHMSQA	CIZ1	616	Q9ULV3
NHANQEVQRHATGAM	PKP3	371	Q9Y446
MQSRAVDGFHSEEQQ	GTF2A1	51	P52655
ETGQDARAAMNLHNN	WNT8B	151	Q93098
QMRNSQAHRNFLEDG	TMEM59	211	Q9BXS4
MTRENVAHNALRQEG	ZNF197	1	O14709
TQHVNISQADMQAIG	ZNF143	506	P52747
EQMASVQNAQRDNAG	TJP2	666	Q9UDY2
MQSHAADNENNIASN	ZNF618	411	Q5T7W0
EQATVLRNLGMAHNA	TTC24	271	A2A3L6
GKRFQAQSALQQHME	ZBTB16	496	Q05516
EHVMNVGNQNRSVGA	KIF3B	191	O15066
EQSQHLDGERMQAAA	TICAM1	551	Q8IUC6
DARSAMNKHNNEAGR	WNT3	181	P56703
ANMRFLHQDATQTGE	ZNF211	196	Q13398
AELRQVQSQAHGLQM	SMC1A	696	Q14683
MNLHNNEAGRQAVAK	WNT16	201	Q9UBV4
LNQDIMHQQQDVGSR	USF3	1596	Q68DE3
HGSNQKESVFMRLNN	SUCO	906	Q9UBS9
FNQSSHQKNVDARME	UAP1	56	Q16222
SAMNRHNNEAGRQAI	WNT3A	181	P56704
QNSQMVHNGQIIATD	ZCCHC9	81	Q8N567
QQGNQERHLREMFTH	ZNF286B	166	P0CG31
DMSNIRSQHAEEQSN	USP34	3426	Q70CQ2
VEMNQGQSQGTVDQH	TET2	636	Q6N021
LQNQTMVRQFQGHTD	TLE2	576	Q04725
AVENEHMNRLQSQRA	VTI1B	116	Q9UEU0
QSRAQINHSIAMQNG	MYOZ2	76	Q9NPC6
DALNVEHSRNAMQIQ	NEB	1661	P20929