Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNHD1 DYNC2H1 DNAH1

3.12e-05182084GO:0008569
GeneOntologyMolecularFunctionsmall GTPase binding

LRRK2 RTKN RPTOR RIN2 DIAPH3 RIC1 ANKFY1 ASB14 ASB15 APPL2 DEPDC5 TNFAIP1 USP33

3.40e-0532120813GO:0031267
GeneOntologyMolecularFunctiondeubiquitinase activity

USP20 ZUP1 USP44 USP15 USP49 PRPF8 USP26 USP33

4.75e-051242088GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP20 ZUP1 USP44 USP15 USP49 PRPF8 USP26 USP33

9.60e-051372088GO:0019783
GeneOntologyMolecularFunctionGTPase binding

LRRK2 RTKN RPTOR RIN2 DIAPH3 RIC1 ANKFY1 ASB14 ASB15 APPL2 DEPDC5 TNFAIP1 USP33

1.09e-0436020813GO:0051020
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNHD1 DYNC2H1 DNAH1

1.92e-04282084GO:0051959
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP20 ZUP1 USP44 USP15 USP49 USP26 USP33

1.93e-041142087GO:0004843
GeneOntologyMolecularFunctionendothelin receptor activity

EDNRA EDNRB

3.22e-0432082GO:0004962
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNHD1 DYNC2H1 DNAH1

5.77e-04372084GO:0045505
GeneOntologyMolecularFunctionATP-dependent activity

ATP8A2 DNAH14 MYO5C MDN1 ATP11B DNHD1 DYNC2H1 ANXA1 CHD9 ZNFX1 MSH5 ABCC6 NLRP3 DNAH1 ATAD3B ATP6V1H

7.34e-0461420816GO:0140657
MousePhenohead spot

EIF3CL KIT EDNRB EIF3C

3.29e-06101604MP:0002939
DomainARM-type_fold

CAB39 SMG1 LRRK2 MIF4GD FOCAD RPTOR ATXN10 DIAPH3 GCN1 TARBP1 HSF2BP ZNFX1 APOB ARMCX3 KIFAP3 ATP6V1H NUP188 PUM1

3.99e-0833920518IPR016024
DomainZnF_UBP

USP20 USP44 USP49 USP33

4.38e-06112054SM00290
DomainDynein_HC_stalk

DNAH14 DNHD1 DYNC2H1 DNAH1

1.29e-05142054IPR024743
DomainZnf_UBP

USP20 USP44 USP49 USP33

1.29e-05142054IPR001607
Domainzf-UBP

USP20 USP44 USP49 USP33

1.29e-05142054PF02148
DomainMT

DNAH14 DNHD1 DYNC2H1 DNAH1

1.29e-05142054PF12777
DomainZF_UBP

USP20 USP44 USP49 USP33

1.29e-05142054PS50271
DomainDHC_fam

DNAH14 DNHD1 DYNC2H1 DNAH1

1.75e-05152054IPR026983
DomainDynein_heavy

DNAH14 DNHD1 DYNC2H1 DNAH1

1.75e-05152054PF03028
DomainDynein_heavy_dom

DNAH14 DNHD1 DYNC2H1 DNAH1

1.75e-05152054IPR004273
DomainDUSP

USP20 USP15 USP33

2.54e-0562053PF06337
DomainDUSP

USP20 USP15 USP33

2.54e-0562053SM00695
DomainDUSP

USP20 USP15 USP33

4.42e-0572053PS51283
Domain-

USP20 USP15 USP33

4.42e-05720533.30.2230.10
DomainPept_C19_DUSP

USP20 USP15 USP33

4.42e-0572053IPR006615
DomainARM-like

CAB39 SMG1 LRRK2 RPTOR ATXN10 GCN1 TARBP1 HSF2BP ARMCX3 KIFAP3 ATP6V1H PUM1

4.57e-0527020512IPR011989
DomainUSP_CS

USP20 USP44 USP15 USP49 USP26 USP33

8.54e-05662056IPR018200
DomainUSP_1

USP20 USP44 USP15 USP49 USP26 USP33

1.19e-04702056PS00972
DomainEIF3C_N_dom

EIF3CL EIF3C

1.20e-0422052IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

1.20e-0422052PF05470
DomainEndthln_rcpt

EDNRA EDNRB

1.20e-0422052IPR000499
DomainEIF3C

EIF3CL EIF3C

1.20e-0422052IPR027516
DomainUCH

USP20 USP44 USP15 USP49 USP26 USP33

1.29e-04712056PF00443
DomainUSP_2

USP20 USP44 USP15 USP49 USP26 USP33

1.29e-04712056PS00973
DomainUSP_3

USP20 USP44 USP15 USP49 USP26 USP33

1.39e-04722056PS50235
DomainUSP_dom

USP20 USP44 USP15 USP49 USP26 USP33

1.39e-04722056IPR028889
DomainPeptidase_C19_UCH

USP20 USP44 USP15 USP49 USP26 USP33

1.39e-04722056IPR001394
Domain-

CAB39 LRRK2 RPTOR ATXN10 GCN1 HSF2BP ARMCX3 KIFAP3 ATP6V1H PUM1

1.77e-04222205101.25.10.10
DomainDUF4683

NEXMIF REV3L

3.57e-0432052PF15735
DomainDUF4683

NEXMIF REV3L

3.57e-0432052IPR032757
Domain-

TRPC3 TRPC6 LRRK2 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

4.29e-04248205101.25.40.20
DomainDynein_heavy_chain_D4_dom

DNAH14 DYNC2H1 DNAH1

4.34e-04142053IPR024317
DomainDynein_heavy_dom-2

DNHD1 DYNC2H1 DNAH1

4.34e-04142053IPR013602
DomainDHC_N2

DNHD1 DYNC2H1 DNAH1

4.34e-04142053PF08393
DomainATPase_dyneun-rel_AAA

MDN1 DYNC2H1 DNAH1

4.34e-04142053IPR011704
DomainAAA_8

DNAH14 DYNC2H1 DNAH1

4.34e-04142053PF12780
DomainAAA_5

MDN1 DYNC2H1 DNAH1

4.34e-04142053PF07728
DomainAnkyrin_rpt-contain_dom

TRPC3 TRPC6 LRRK2 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

5.17e-0425420510IPR020683
DomainKRAB

ZNF568 ZNF264 ZNF484 ZNF805 ZFP28 ZNF880 ZNF677 ZNF100 ZNF253 ZNF470 ZNF528 ZNF669

6.21e-0435820512PS50805
DomainKRAB

ZNF568 ZNF264 ZNF484 ZNF805 ZFP28 ZNF880 ZNF677 ZNF100 ZNF253 ZNF470 ZNF528 ZNF669

6.21e-0435820512PF01352
DomainAnk_2

TRPC3 TRPC6 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

6.34e-042152059PF12796
DomainAnkyrin_rpt

TRPC3 TRPC6 LRRK2 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

6.57e-0426220510IPR002110
DomainPLDc

PLD3 PLD1

7.09e-0442052PF00614
DomainKRAB

ZNF568 ZNF264 ZNF484 ZNF805 ZFP28 ZNF880 ZNF677 ZNF100 ZNF253 ZNF470 ZNF528 ZNF669

8.09e-0436920512SM00349
DomainKRAB

ZNF568 ZNF264 ZNF484 ZNF805 ZFP28 ZNF880 ZNF677 ZNF100 ZNF253 ZNF470 ZNF528 ZNF669

8.28e-0437020512IPR001909
DomainAnk

TRPC3 TRPC6 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

9.61e-042282059PF00023
Domain-

TDRD15 RNF17

1.75e-03620522.40.50.90
DomainTRP_2

TRPC3 TRPC6

1.75e-0362052PF08344
DomainStaphylococal_nuclease_OB-fold

TDRD15 RNF17

1.75e-0362052IPR016071
DomainPLDc

PLD3 PLD1

1.75e-0362052SM00155
DomainTRP_dom

TRPC3 TRPC6

1.75e-0362052IPR013555
DomainANK

TRPC3 TRPC6 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

1.87e-032512059SM00248
DomainANK_REPEAT

TRPC3 TRPC6 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

1.97e-032532059PS50088
DomainANK_REP_REGION

TRPC3 TRPC6 ANKFY1 UACA ASB14 ASB15 ANKRD55 ASB4 ANKRD7

2.03e-032542059PS50297
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN TRPM7 VPS26C LMO3 TUBGCP5 LRP1B FOCAD CSDE1 SACS ATXN10 TARBP1 VARS1 SOX6 CNTN4 OGT DSP SYNE1 CHD9 ZNFX1 ADAMTS8 REV3L PRPF8 FRY APPL2 RABEP1 ZNF528 EIF3C USP33

5.98e-0912852122835914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STARD8 IP6K1 TUBGCP5 USP20 C2CD5 TTBK1 SACS RIC1 CNTN4 UACA DYNC2H1 ZFP28 ATAD3B VPS13D CMIP TTC21B PLCH1

1.17e-084932121715368895
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

NEXMIF DNAH14 USP20 PRDM2 FOCAD ESRP2 MDN1 PCDH10 MXRA5 DSP REV3L PRPF8 FRY GTF3C1 TNFAIP1 NUP188 TNR TUBE1

7.20e-077362121829676528
Pubmed

Increased gene expression of the cardiac endothelin system in obese mice.

ECE1 EDNRA EDNRB

8.89e-074212325181417
Pubmed

Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells.

TRPM7 TRPC3 TRPC6

8.89e-074212322566504
Pubmed

Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.

ECE1 EDNRA EDNRB

8.89e-07421239449665
Pubmed

Polymorphism in endothelin-related genes limits exercise-induced decreases in arterial stiffness in older subjects.

ECE1 EDNRA EDNRB

8.89e-074212316567585
Pubmed

Expression of endothelin-converting enzyme, endothelin-1 and endothelin receptors at the site of percutaneous coronary intervention in humans.

ECE1 EDNRA EDNRB

8.89e-074212316531800
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

USP20 USP44 GLDC KLHL42 USP15 GCN1 TARBP1 VARS1 USP49 ANKFY1 OGT DYNC2H1 ANXA1 KRR1 PRPF8 USP26 ATAD3B TNFAIP1 EIF3C NUP188 USP33

1.06e-0610052122119615732
Pubmed

Hereditary Ataxia Overview

TRPC3 PLD3 SACS ATXN10 SYNE1 VPS13D PUM1

1.60e-0692212720301317
Pubmed

Regulation of retinoblastoma gene expression in a mouse mammary tumor model.

ECE1 EDNRA EDNRB

2.21e-06521238548579
Pubmed

Endothelin in the central control of cardiovascular and respiratory functions.

ECE1 EDNRA EDNRB

2.21e-065212310626068
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CAB39 PLD3 F13B ATXN10 GCN1 KRT9 KRT14 OGT KRT16 DSP ANXA1 VPS13D RABEP1 CNTNAP2 NUP188

2.27e-065642121521565611
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

VPS26C USP20 ZUP1 C2CD5 USP15 UACA DEPDC5 USP33

3.60e-06147212829576527
Pubmed

Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission.

C5 KIT RAG2

4.41e-066212335840625
Pubmed

Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

KRT14 KRT16 TNFRSF1A

4.41e-066212316702408
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYO5C GCN1 KRT9 KRT14 UACA DSP ZNFX1 PRPF8 CNTNAP2

4.58e-06202212933005030
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

IFT140 MIS18BP1 STARD8 PLD3 CHKA ELAC2 USP20 MDN1 GLDC GLE1 ATXN10 RNASEH2B MMS22L CHD9 KIFAP3 ZNF106 ATAD3B CMIP AKAP9 APPL2 TNFAIP1 USP33

8.28e-0612422122230973865
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FOCAD CSDE1 FBXO28 USP15 PCDH10 ANKFY1 SYNE1 RSBN1 AKAP9 DZIP3 PUM1 USP33

8.61e-064072121212693553
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

EFCAB5 CSDE1 C17orf75 MDN1 ATXN10 GCN1 VARS1 UACA DSP POLRMT CHD9 NAA50 PRPF8 CTSA KIFAP3 ATAD3B EIF3C

1.09e-058092121732129710
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

CAB39 SMG1 ATXN10 ZFAT ANKFY1 UACA DSP SYNE1 AKAP9 APPL2 RABEP1 EIF3C SMAD3

1.30e-054972121323414517
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

ZUP1 KRT9 KRT14 KRT16 DSP PRPF8

1.31e-0584212629563501
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CAB39 LRRK2 PLD3 ACY1 C5 RHOF DNHD1 MXRA5 ANKFY1 UACA DSP DYNC2H1 ANXA1 NAA50 ECE1 CTSA VPS13D ATP6V1H APPL2

1.68e-0510162121919056867
Pubmed

Venous endothelin guides sympathetic innervation of the developing mouse heart.

ECE1 EDNRA EDNRB

1.83e-059212324875861
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

SMG1 EIF3CL ABCC6 GTF3C1 EIF3C PMFBP1

2.20e-0592212610493829
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RGS22 PRDM2 EIF3CL MDN1 RPTOR ATXN10 GCN1 VARS1 DNHD1 ANKFY1 DSP DYNC2H1 SYNE1 POLRMT APOB KRR1 PRPF8 ATP6V1H GTF3C1 RBPJ EIF3C NUP188 PUM1

2.24e-0514252122330948266
Pubmed

Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

TRPC6 ECE1 EDNRA EDNRB RBPJ SMAD3

2.49e-0594212620346360
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPM7 TRPC3 TRPC6

2.60e-0510212327177420
Pubmed

Heterogeneous distribution of TRPC proteins in the embryonic cortex.

RELN TRPC3 TRPC6

2.60e-0510212318989690
Pubmed

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

EIF3CL RPTOR EIF3C

2.60e-0510212316286006
Pubmed

The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.

TRPC3 KIT CNTN4 OGT PLCH1 TNR

3.15e-0598212619554387
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

LRP1B STAB2 EFCAB6 ANKRD55 ABCC6 FRY CNTNAP2 PLCH1

3.27e-05199212823382691
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

TIPRL C2CD5 PRUNE1 PEX2 ATXN10 DIAPH3 GCN1 VARS1 OGT POLRMT PRPF8 ARMCX3 PTPN5 ATP6V1H GTF3C1 EIF3C NUP188 MAPK3

3.30e-059742121828675297
Pubmed

Intradermal administration of thymic stromal lymphopoietin induces a T cell- and eosinophil-dependent systemic Th2 inflammatory response.

KIT RAG2 TNFRSF1A

3.55e-0511212318768889
Pubmed

Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons.

ECE1 EDNRA EDNRB

3.55e-0511212318401410
Pubmed

Lack of TNFRI signaling enhances annexin A1 biological activity in intestinal inflammation.

ANXA1 TNFRSF1A

3.70e-052212226386311
Pubmed

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.

TRPC3 TRPC6

3.70e-052212222724068
Pubmed

NLRP3 inflammasome activation triggers gasdermin D-independent inflammation.

NLRP3 GSDMD

3.70e-052212234678046
Pubmed

Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.

EDNRA EDNRB

3.70e-052212232744876
Pubmed

Identification of a novel role for endothelins within the oviduct.

EDNRA EDNRB

3.70e-052212220357223
Pubmed

Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis.

KIT RAG2

3.70e-052212218981146
Pubmed

The association of NLRP3 and TNFRSF1A polymorphisms with risk of ankylosing spondylitis and treatment efficacy of etanercept.

NLRP3 TNFRSF1A

3.70e-052212228116820
Pubmed

Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.

PTPN5 OTOG

3.70e-05221227490079
Pubmed

Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.

EDNRA EDNRB

3.70e-052212224582810
Pubmed

Modulation of Transient Receptor Potential Channels 3 and 6 Regulates Osteoclast Function with Impact on Trabecular Bone Loss.

TRPC3 TRPC6

3.70e-052212232140760
Pubmed

Endothelin ETA and ETB receptor expression in the human trigeminal ganglion.

EDNRA EDNRB

3.70e-052212216816835
Pubmed

Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism.

EDNRA EDNRB

3.70e-052212211376172
Pubmed

ETA and ETB receptors are expressed in vascular adventitial fibroblasts.

EDNRA EDNRB

3.70e-052212221949113
Pubmed

Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.

EDNRA EDNRB

3.70e-052212219299580
Pubmed

Increased gene expression and production of murine endothelin receptors after birth.

EDNRA EDNRB

3.70e-052212212763050
Pubmed

Down-regulation of ETA receptors in ETB receptor-deficient mice.

EDNRA EDNRB

3.70e-052212215838300
Pubmed

Real-time polymerase chain reaction quantification of gene expression levels of murine endothelin-A and endothelin-B receptors: gene expression profiles by the standard curve method.

EDNRA EDNRB

3.70e-052212215838311
Pubmed

MicroRNA‑1929‑3p participates in murine cytomegalovirus‑induced hypertensive vascular remodeling through Ednra/NLRP3 inflammasome activation.

EDNRA NLRP3

3.70e-052212233416142
Pubmed

Endothelin receptor pharmacology and function in the mouse: comparison with rat and man.

EDNRA EDNRB

3.70e-052212215838332
Pubmed

Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera.

EDNRA EDNRB

3.70e-052212215838285
Pubmed

Upregulation of vascular ET(B) receptor gene expression after chronic ET(A) receptor blockade in prediabetic NOD mice.

EDNRA EDNRB

3.70e-052212215838254
Pubmed

LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis-Mediated Gut Inflammation.

LRRK2 GSDMD

3.70e-052212238607004
Pubmed

Targeting endothelin receptors A and B attenuates the inflammatory response and improves locomotor function following spinal cord injury in mice.

EDNRA EDNRB

3.70e-052212224756152
Pubmed

O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis.

OGT GSDMD

3.70e-052212237962578
Pubmed

DHA induces Jurkat T-cell arrest in G2/M phase of cell cycle and modulates the plasma membrane expression of TRPC3/6 channels.

TRPC3 TRPC6

3.70e-052212233333171
Pubmed

Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.

EDNRA EDNRB

3.70e-052212212875994
Pubmed

Associations of EDNRA and EDNRB Polymorphisms with Intracerebral Hemorrhage.

EDNRA EDNRB

3.70e-052212231150867
Pubmed

Expression and significance of effector proteins NLRP3 and gasdermin D N-terminal protein in the pyrolysis pathway in breast cancer.

NLRP3 GSDMD

3.70e-052212237800794
Pubmed

Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease.

C5 KIT

3.70e-052212223071133
Pubmed

Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy.

TRPC3 TRPC6

3.70e-052212225213992
Pubmed

Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.

EDNRA EDNRB

3.70e-052212218784261
Pubmed

Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries.

EDNRA EDNRB

3.70e-052212214729387
Pubmed

TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes.

TRPC3 TRPC6

3.70e-052212228105583
Pubmed

Dysregulation of vascular TRPM7 and annexin-1 is associated with endothelial dysfunction in inherited hypomagnesemia.

TRPM7 ANXA1

3.70e-052212219103997
Pubmed

Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.

TRPC3 TRPC6

3.70e-052212235051376
Pubmed

Blood pressure regulation by ETA and ETB receptors in conscious, telemetry-instrumented mice and role of ETA in hypertension produced by selective ETB blockade.

EDNRA EDNRB

3.70e-052212216399858
Pubmed

Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein.

TRPC3 TRPC6

3.70e-05221229368034
Pubmed

Role of endothelin-1 and its receptors, ETA and ETB, in the survival of human vascular endothelial cells.

EDNRA EDNRB

3.70e-052212228732172
Pubmed

Ovarian hormones modulate endothelin-1 receptor responses in young women.

EDNRA EDNRB

3.70e-052212229999581
Pubmed

Expression analysis of two cancer-testis genes, FBXO39 and TDRD4, in breast cancer tissues and cell lines.

FBXO39 RNF17

3.70e-052212224377578
Pubmed

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.

LRRK2 GSDMD

3.70e-052212235907404
Pubmed

Expression of endothelin receptors in frog, chicken, mouse and human pigment cells.

EDNRA EDNRB

3.70e-052212216962346
Pubmed

The expression of endothelin type A and B receptors in the lateral wall of the mouse cochlea.

EDNRA EDNRB

3.70e-052212217607529
Pubmed

Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages.

ANXA1 NLRP3

3.70e-052212232283822
Pubmed

The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16.

KRT14 KRT16

3.70e-052212210477769
Pubmed

Expression of endothelin receptor subtypes in bronchial tumors.

EDNRA EDNRB

3.70e-052212220043107
Pubmed

[Mechanism of cardiac hypertrophy via diacylglycerol-sensitive TRPC channels].

TRPC3 TRPC6

3.70e-052212220190513
Pubmed

Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.

EDNRA EDNRB

3.70e-052212214636059
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3CL EIF3C

3.70e-052212236157221
Pubmed

Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils.

ANXA1 NLRP3

3.70e-052212233440601
Pubmed

Molecular characterization and regulation of the human endothelin receptors.

EDNRA EDNRB

3.70e-05221228440682
Pubmed

Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension.

EDNRA EDNRB

3.70e-052212222688668
Pubmed

Phospholipase D1 and choline kinase-α are interactive targets in breast cancer.

CHKA PLD1

3.70e-052212224556997
Pubmed

Gasdermin-D activation promotes NLRP3 activation and host resistance to Leishmania infection.

NLRP3 GSDMD

3.70e-052212236828815
Pubmed

Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice.

EDNRA EDNRB

3.70e-052212210198387
Pubmed

[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells].

EDNRA EDNRB

3.70e-05221221291713
Pubmed

Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ETB knockout mice.

EDNRA EDNRB

3.70e-052212222365955
Pubmed

Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans.

TEX11 USP26

3.70e-052212233978233
Pubmed

Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer.

RAG2 SMAD3

3.70e-052212219119184
Pubmed

Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice.

RPTOR CTSK

3.70e-052212227879318
Pubmed

N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.

TRPC3 TRPC6

3.70e-052212212970363
Pubmed

cDNA cloning, expression, and assembly characteristics of mouse keratin 16.

KRT14 KRT16

3.70e-05221229822705
Pubmed

Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.

USP20 USP33

3.70e-052212233792613
Pubmed

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.

TRPC3 TRPC6

3.70e-05221229930701
Pubmed

Facial hyperalgesia due to direct action of endothelin-1 in the trigeminal ganglion of mice.

EDNRA EDNRB

3.70e-052212229570803
InteractionSYNC interactions

TUBGCP5 KLHL42 CCDC136 KRT14 KRT16 UACA RABEP1

5.45e-06672067int:SYNC
InteractionZUP1 interactions

VPS26C ZUP1 C2CD5 KRT9 KRT14 KRT16 UACA DSP PRPF8 DEPDC5

1.26e-0517420610int:ZUP1
InteractionKRT8 interactions

SMG1 HAUS4 DIAPH3 KRT14 OGT KRT16 ZNF484 UACA DSP ANXA1 PRPF8 AKAP9 RABEP1 NUP188 MAPK3 PUM1

1.31e-0544120616int:KRT8
InteractionC3orf18 interactions

SMG1 IP6K1 MDN1 SACS KLHL42 DIAPH3 TARBP1 DYNC2H1

2.41e-051152068int:C3orf18
GeneFamilyUbiquitin specific peptidases

USP20 USP44 USP15 USP49 USP26 USP33

6.06e-06561476366
GeneFamilyEndothelin receptors

EDNRA EDNRB

6.57e-0521472225
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF568 ZUP1 ZNF264 ZFAT ZNF484 ZNF805 ZFP28 ZNF880 ZNF677 ZNF106 ZNF100 ZNF253 ZNF470 ZNF528 ZNF669

7.63e-047181471528
GeneFamilyTransient receptor potential cation channels

TRPM7 TRPC3 TRPC6

1.49e-03281473249
GeneFamilyKeratins, type I

KRT9 KRT14 KRT16

1.49e-03281473608
GeneFamilyAdenosine deaminases acting on RNA

ADAT2 ADAT1

1.78e-03814721303
CoexpressionGSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN

LMO3 HMGCS1 MYO5C TXK DIAPH3 USP15 KRT14 POLRMT ECE1 SERPINA6 MX2

6.01e-0719820911M5571
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

ZDHHC2 SMG1 GALNT7 USP44 RNASEH2B ZNF880 ATP6V1H DZIP3 ZNF528 PUM1

4.83e-0619920910M9238
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

IP6K1 ACY1 ESRP2 RHOF HIPK2 ZFP28 VPS13D GSDMD RBPJ MX2

5.05e-0620020910M6035
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA2

ATP8A2 LMO3 LRFN5 SOX6 USP49 CNTN4 ZNFX1 REV3L RNF17 PTPN5 KIFAP3 FRY CMIP CNTNAP2 ASB4

1.74e-0551320915M39069
CoexpressionAKL_HTLV1_INFECTION_DN

ATP8A2 ANXA1 REV3L CTSA FRY AKAP9

1.89e-05692096M9815
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

SMG1 TRPM7 NEXMIF NR6A1 PLD3 CHKA GALNT7 ZUP1 FOCAD ATP11B SACS CNTN4 ANKFY1 HSF2BP CHD9 TEX11 ECE1 RNF17 EDNRA ATP6V1H APPL2 DZIP3 DEPDC5 PUM1

9.66e-0779520724gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

SMG1 CHKA RPTOR GCN1 OGT HIPK2 REV3L EDNRA EDNRB RSBN1 AKAP9 APPL2 ASB4 PUM1 TUBE1

6.10e-0638520715gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN RGS22 LRP1B PCDH10 STAB2 EFCAB6 APOB TEX11 DNAH1 PLCH1 OTOG

1.45e-09184212112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN RGS22 LRP1B PCDH10 STAB2 EFCAB6 APOB TEX11 DNAH1 PLCH1 OTOG

1.45e-09184212112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN RGS22 LRP1B PCDH10 STAB2 EFCAB6 APOB TEX11 DNAH1 PLCH1 OTOG

1.45e-0918421211ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PXDNL CNTN4 CACNA1D COL6A6 DYNC2H1 SYNE1 ADAMTS8 REV3L EDNRA AKAP9 GTF3C1

3.49e-09200212119b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC2 RTKN HAUS4 DIAPH3 USP49 HSF2BP PTPN5 TUBE1 CTSK SMAD3

2.04e-0818421210b998803180322a5ea2b567928dea531c26816c3c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP8A2 FOCAD LRFN5 TARBP1 CNTN4 CACNA1D SYNE1 KIFAP3 FRY CNTNAP2

3.72e-0819621210676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP8A2 FOCAD LRFN5 TARBP1 CNTN4 CACNA1D SYNE1 KIFAP3 FRY CNTNAP2

4.09e-08198212106d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP8A2 FOCAD LRFN5 TARBP1 CNTN4 CACNA1D SYNE1 KIFAP3 FRY CNTNAP2

4.09e-08198212104ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

ATP8A2 FOCAD LRFN5 TARBP1 CNTN4 CACNA1D SYNE1 KIFAP3 FRY CNTNAP2

4.50e-082002121048d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

ACY1 C2CD5 CACNA1D OGT DYNC2H1 SYNE1 CHD9 CMTR2

2.82e-071352128ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 LMO3 NR6A1 DNAH14 TTC6 MYO5C MTUS1 CNTN4 ABCC6

2.84e-0718621292ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LRRK2 LMO3 TTC6 CNTN6 MYO5C DSP ABCC6 FRY PLCH1

3.10e-0718821290d86044bc340e3efb90d0022dd299873639d831c
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 CNTN4 ABCC6 PLCH1

3.71e-071922129499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 CNTN4 ABCC6 PLCH1

3.71e-071922129efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 LMO3 CHKA DNAH14 TTC6 MYO5C MTUS1 ABCC6 PLCH1

3.87e-071932129a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMO3 TTC6 CNTN6 MYO5C ESRP2 C5 DSP FRY PLCH1

4.22e-071952129d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP8A2 FOCAD LRFN5 CNTN4 CACNA1D SYNE1 KIFAP3 FRY CNTNAP2

4.80e-071982129c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PXDNL CNTN4 CACNA1D COL6A6 DYNC2H1 SYNE1 ADAMTS8 REV3L EDNRA

5.01e-071992129a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN TRPC6 RIN2 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

5.22e-072002129347a510755374c6a66acee326565dfc447993f18
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 HMGCS1 NR6A1 TTC6 MYO5C USP44 MTUS1 CNTN4

2.10e-0617621283bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 NR6A1 TTC6 CNTN6 MYO5C USP44 MTUS1 CNTN4

2.38e-061792128cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN MTUS1 CTHRC1 STAB2 UACA DSP EDNRB FRY

2.38e-06179212899777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TTC6 MYO5C TXK ESRP2 GLDC C5 FRY PLCH1

2.92e-061842128fa4915b0498f3069fd5ef497286445528f75187e
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

C2CD5 FOCAD C17orf75 FBXO28 KLHL42 ATP6V1H CMTR2 ADAT2

3.04e-061852128e06a784a297f357f3f8e761c24fa70722048ab42
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 LMO3 NR6A1 TTC6 MYO5C USP44 MTUS1 CNTN4

3.04e-06185212898b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

NEXMIF LMO3 TTC6 MYO5C MTUS1 CNTN4 DSP PLCH1

3.04e-061852128cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

LRRK2 LMO3 NR6A1 TTC6 MYO5C USP44 MTUS1 CNTN4

3.30e-06187212881cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IFT140 FZD4 RIN2 UACA SYNE1 EDNRB FRY TNR

3.57e-061892128b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LMO3 TTC6 MYO5C ESRP2 DSP ABCC6 FRY PLCH1

3.71e-061902128c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 CNTN4 PLCH1

3.86e-061912128e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 ABCC6 PLCH1

3.86e-061912128276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

3.86e-061912128de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 ABCC6 PLCH1

3.86e-061912128ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 LMO3 HMGCS1 DNAH14 MYO5C MTUS1 CNTN4 PLCH1

4.01e-061922128cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

LRRK2 LMO3 HMGCS1 DNAH14 MYO5C MTUS1 CNTN4 PLCH1

4.01e-06192212806013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

4.01e-061922128dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

4.16e-061932128010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

4.16e-0619321282189da4b727e25e62669d7b9257f06493be21a27
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

4.16e-0619321283ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMO3 TTC6 CNTN6 MYO5C USP44 DSP FRY PLCH1

4.16e-061932128b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 GPR82 TUBGCP5 TXK OGT SYNE1 TEX11 AKAP9

4.16e-0619321289337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5C KIT EFCAB6 UACA DSP ANKRD55 EDNRB

4.49e-0613821275f8ac8f67e34a7cf560099208e6884102532391e
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRK2 LMO3 NR6A1 DNAH14 MYO5C MTUS1 SYNE1 PLCH1

4.49e-0619521289406866f99555198a9be311fbd65751b70f35446
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

LRRK2 MTUS1 PXDNL COL6A6 DYNC2H1 SYNE1 CHD9 AKAP9

4.84e-0619721280a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

LRRK2 TTC6 MYO5C MTUS1 C5 SOX6 DSP AKAP9

4.84e-06197212844a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRRK2 TTC6 MYO5C USP44 MTUS1 C5 DSP AKAP9

5.03e-061982128285f729140b1df029c24f6ca1d2438470ac51794
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 LMO3 HMGCS1 NR6A1 MYO5C USP44 MTUS1 PLCH1

5.03e-061982128f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP8A2 LRFN5 TARBP1 CNTN4 CACNA1D KIFAP3 FRY CNTNAP2

5.03e-0619821280ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LMO3 NR6A1 CHKA DNAH14 TTC6 MYO5C MTUS1 PLCH1

5.22e-0619921285f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LMO3 NR6A1 CHKA DNAH14 TTC6 MYO5C MTUS1 PLCH1

5.22e-0619921285cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRRK2 LMO3 TTC6 MYO5C MTUS1 C5 DSP AKAP9

5.41e-062002128e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

5.41e-062002128858421b91f5207b7934b5c219752cb9322a3da31
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

5.41e-062002128a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN TRPC6 CCDC136 SOX6 ANKRD55 EDNRA CNTNAP2 PLCH1

5.41e-0620021282131c8e7fa054b79906eaf60536da892438b09cd
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NEXMIF TRPC6 HMGCS1 KIT HTR7 REV3L ZNF669

1.00e-0515621270f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NEXMIF TRPC6 HMGCS1 KIT HTR7 REV3L ZNF669

1.00e-051562127cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

NR6A1 PEX2 SOX6 USP49 REV3L EDNRB ZNF106

1.14e-051592127fb222c42f66901852b01cec073ec0732245ee973
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MTUS1 ABCC6 ASB4

1.14e-051592127e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TXK EFCAB6 EDNRB PTPN5 ADAT1 MX2

1.14e-0515921274000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TXK EFCAB6 EDNRB PTPN5 ADAT1 MX2

1.14e-0515921277619d0d49738dd08daf01b42664691a5323aa793
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

LRP1B MDN1 SYNE1 HIPK2 VPS13D DZIP3 TNR

2.27e-051772127e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 DIAPH3 CNTN4 KRT14 COL6A6 ADAT2 ANKRD7

2.27e-0517721274197cf2b1e743230c821f422836fa5991b155a52
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN6 MYO5C RHOF SOX6 DSP ANXA1 MX2

2.36e-051782127aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 KRT14 KRT16 APOB RNF17 EDNRA CTSK

2.36e-0517821276d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 KRT14 KRT16 APOB RNF17 EDNRA CTSK

2.36e-051782127d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LMO3 CHKA MYO5C MTUS1 C5 PLCH1

2.44e-051792127fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NEXMIF ATP8A2 SOX6 MXRA5 DYNC2H1 EDNRB FRY

2.44e-051792127a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellmild-B_cell|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

STARD8 CHKA ELAC2 METTL16 ZFAT MSH5 ZNF253

2.81e-051832127175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LMO3 CHKA MYO5C MTUS1 C5 PLCH1

2.81e-051832127e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRRK2 LMO3 HMGCS1 TTC6 MYO5C MTUS1 PLCH1

2.91e-051842127369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

RGS22 LRFN5 KIT CNTN4 REV3L EDNRB ZNF106

2.91e-05184212767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LMO3 MYO5C MTUS1 C5 SOX6 PLCH1

3.02e-0518521270d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 CNTN6 MYO5C C5 SOX6 DSP ANXA1

3.02e-0518521273937e026add96a396122139daf8011cfbc60e75c
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RELN GLDC CACNA1D ABCC6 CMIP PUM1 SMAD3

3.02e-0518521271d874608aa2062024323512f68889219471b2f00
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 NR6A1 CHKA CNTN6 MYO5C MTUS1 C5

3.12e-0518621274e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LMO3 CHKA MYO5C MTUS1 C5 PLCH1

3.12e-051862127e83718fabb057100835d3357df407f283d23fe16
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN TRPC6 CTHRC1 SOX6 KRT9 ZNF484

3.14e-05126212694bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 CHKA CNTN6 MYO5C MTUS1 C5 DSP

3.23e-05187212758d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NEXMIF ATP8A2 TRPC3 RTKN STAB2 ECE1

3.34e-051882127a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LMO3 CHKA MYO5C MTUS1 C5 PLCH1

3.34e-0518821274bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NEXMIF ATP8A2 TRPC3 RTKN STAB2 ECE1

3.34e-05188212754550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

LRRK2 HMGCS1 DNAH14 MTUS1 C5 CACNA1D PLCH1

3.34e-051882127ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMO3 TTC6 CNTN6 MYO5C DSP FRY PLCH1

3.34e-051882127beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 CHKA CNTN6 MYO5C MTUS1 C5 DSP

3.34e-05188212743a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

LRRK2 LMO3 NR6A1 DNAH14 MYO5C MTUS1 PLCH1

3.34e-051882127707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 CNTN6 MYO5C MTUS1 C5 KRT16 ANXA1

3.46e-0518921275f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 NR6A1 LRP1B MYO5C SOX6 CACNA1D DYNC2H1

3.46e-051892127975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MYO5C USP44 ESRP2 GLDC DIAPH3 DSP ABCC6

3.46e-051892127a6c62b456982067ad4d224a2efa3919969000693
ToppCellIPF-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

LRRK2 USP44 ECE1 NLRP3 OSM MX2 SMAD3

3.46e-051892127ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 CHKA TTC6 MYO5C C5 FRY PLCH1

3.58e-0519021278aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRRK2 LMO3 TTC6 MYO5C MTUS1 ABCC6 PLCH1

3.58e-05190212727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 DNAH14 TTC6 MTUS1 C5 SOX6 PLCH1

3.70e-05191212734cc997e4e5c727495f321e6807a84aa124da486
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF CHKA MYO5C ESRP2 DSP TEX11 C6orf132

3.70e-051912127c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TRPC6 CACNA1D MXRA5 COL6A6 UACA ADAMTS8 EDNRA

3.70e-051912127e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ATP8A2 C17orf75 RHOF HTR7 HAP1 PTPN5 CNTNAP2

3.70e-0519121275d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ATP8A2 C17orf75 RHOF HTR7 HAP1 PTPN5 CNTNAP2

3.70e-05191212773dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TRPC6 LRFN5 CACNA1D COL6A6 UACA ADAMTS8 EDNRA

3.70e-0519121276688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellfacs-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF CHKA MYO5C ESRP2 DSP TEX11 C6orf132

3.70e-0519121275f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

LRRK2 LMO3 DNAH14 TTC6 MYO5C MTUS1 CNTN4

3.70e-051912127d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TRPC6 CACNA1D MXRA5 COL6A6 UACA ADAMTS8 EDNRA

3.70e-0519121271726add3f392a061536b7aff72ba84303f4a0b1f
DrugLOE 908

TRPM7 HTR7 EDNRA EDNRB MAPK3

4.83e-07182095CID000122081
Drugphosphoramidon

ECE1 EDNRA EDNRB MAPK3

1.15e-05162094ctd:C008890
Drugphenyl isocyanate

KRT9 KRT14 KRT16

1.49e-0562093ctd:C025319
DrugSKF-7261

RAG2 KRT14 KRT16 TNFAIP1 TNFRSF1A

2.44e-05382095CID000015773
Drug19-oxo-11-deoxycorticosterone acetate

EDNRA EDNRB MAPK3

2.60e-0572093ctd:C040168
Drugclazosentan

EDNRA EDNRB TNFRSF1A

4.13e-0582093CID006433095
DrugAC1L1JVU

TRPM7 TRPC6 CACNA1D NAA50 EDNRA MAPK3

5.25e-05722096CID000005229
DrugFlunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A

PRDM2 MTUS1 ZNF264 ANKFY1 HIPK2 RABEP1 CNTNAP2 PCNX1 TNFAIP1

7.11e-0519120994273_DN
DrugMagnetite Nanoparticles

ZDHHC2 SMG1 TRPM7 GPR84 HMGCS1 PLD3 CHKA ACY1 GALNT7 ZUP1 PRDM2 ALKBH8 SACS KIT RHOF CHD9 MSH5 NAA50 REV3L KRR1 NLRP3 AKAP9 ZNF253 DZIP3 TNFRSF1A CTSK ADAT1

7.13e-05131020927ctd:D058185
DrugFuroxanobenzofuroxan

GNPAT ECE1 EDNRA EDNRB PUM1

7.72e-05482095CID000313608
DrugAC1L9K72

ATP8A2 PLD3 CHKA ACY1 PEX2 PLD1 ANXA1 APOB CTSA ABCC6 PLCH1

8.14e-0529020911CID000446872
DrugMetaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A

STARD8 TRPC3 LMO3 NR6A1 MTUS1 PGLYRP4 NLRP3 CNTNAP2 INO80B

8.33e-0519520993669_UP
DrugBosentan

EDNRA EDNRB

8.39e-0522092DB00559
DrugTAK 044

EDNRA EDNRB

8.39e-0522092ctd:C088196
Drug6-bromo-2,3-dihydrobenzofuran

EDNRA EDNRB

8.39e-0522092CID011252616
DrugUltravate

ANXA1 SERPINA6

8.39e-0522092CID000048175
Drug1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-

EDNRA EDNRB

8.39e-0522092ctd:C087551
DrugIRL 1620

EDNRA EDNRB

8.39e-0522092ctd:C074308
Drugenrasentan

EDNRA EDNRB

8.39e-0522092ctd:C098288
DrugPD 145065

EDNRA EDNRB

8.39e-0522092ctd:C082887
DrugLU 224332

EDNRA EDNRB

8.39e-0522092ctd:C113044
DrugSitaxentan

EDNRA EDNRB

8.39e-0522092DB06268
DrugA 182086

EDNRA EDNRB

8.39e-0522092ctd:C467893
DrugPD 156252

EDNRA EDNRB

8.39e-0522092ctd:C106950
DrugL-671,776

EDNRA EDNRB

8.39e-0522092CID000122853
Drugtezosentan

EDNRA EDNRB

8.39e-0522092ctd:C120582
Drugspirodihydrobenzofuranlactam VI

EDNRA EDNRB

8.39e-0522092CID000469820
DrugJ 104132

EDNRA EDNRB

8.39e-0522092ctd:C119319
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A

NR6A1 FBXL18 METTL16 CACNA1D EFCAB6 HAP1 EDNRA OR1D2 PLCH1

8.67e-0519620993827_UP
DrugHeliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A

METTL16 KRT9 STAB2 HIPK2 OR1D2 CNTNAP2 NUP188 PLCH1 ANKRD7

8.67e-0519620994739_UP
Drug(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A

STARD8 PRDM2 PLD1 METTL16 EFCAB6 ABCC6 EDNRB OR1D2 ZNF528

8.67e-0519620994524_UP
DrugLoracarbef [121961-22-6]; Down 200; 10.8uM; HL60; HT_HG-U133A

METTL16 HIPK2 ECE1 VPS13D APPL2 DZIP3 MAPK3 SMAD3 PMFBP1

9.01e-0519720992970_DN
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; MCF7; HT_HG-U133A

VPS26C PLD3 PRUNE1 GLE1 C5 ANXA1 RABEP1 TNFAIP1 SMAD3

9.01e-0519720997101_DN
DrugBoldine [476-70-0]; Down 200; 12.2uM; PC3; HT_HG-U133A

PLD3 TXK ANKFY1 HSF2BP ECE1 CNTNAP2 PCNX1 ZNF528 INO80B

9.37e-0519820994004_DN
DrugCaptopril [62571-86-2]; Up 200; 17.2uM; PC3; HG-U133A

C17orf75 ATP11B ZNF264 PLD1 TARBP1 MED6 KRR1 KIFAP3 VPS13D

9.37e-0519820991907_UP
Drugvaldecoxib; Down 200; 10uM; PC3; HT_HG-U133A

TRPC3 CACNA1D FRY TTC21B PCNX1 ZNF528 NUP188 PLCH1 INO80B

9.37e-0519820996378_DN
DrugFolic acid [59-30-3]; Up 200; 9uM; HL60; HG-U133A

CHKA PRDM2 DYNC2H1 HIPK2 OR1D2 PCNX1 TNR ZNF669 SMAD3

9.73e-0519920991790_UP
DrugMedrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A

CDK16 VPS26C TIPRL CHKA DYNC2H1 ECE1 VPS13D RABEP1 PLCH1

9.73e-0519920993403_DN
DrugNitrofural [59-87-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A

HMGCS1 TUBGCP5 PRDM2 FZD4 MDN1 METTL16 ANKFY1 KIFAP3 DZIP3

9.73e-0519920995321_DN
DrugICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A

IFT140 RIN2 PLD1 METTL16 MED6 HTR7 VPS13D RABEP1 PLCH1

1.01e-0420020992665_DN
DrugSuccimer

ZDHHC2 SMG1 TRPM7 GPR84 HMGCS1 PLD3 CHKA ACY1 GALNT7 ZUP1 PRDM2 ALKBH8 SACS KIT RHOF CHD9 MSH5 NAA50 REV3L KRR1 NLRP3 AKAP9 ZNF253 DZIP3 CTSK ADAT1

1.01e-04126420926ctd:D004113
Drugbenidipine

ECE1 EDNRA EDNRB MAPK3

1.03e-04272094ctd:C061004
Diseasecommon carotid intimal medial thickness

TDRD15 ATP8A2 DLEC1 MMS22L APOB CNTNAP2

7.33e-06672056EFO_0004860
Diseasevon Willebrand factor measurement, coronary artery disease

TDRD15 STAB2 DYNC2H1 APOB EDNRA SMAD3 PMFBP1

1.94e-051182057EFO_0001645, EFO_0004629
DiseaseCharlevoix-Saguenay spastic ataxia (implicated_via_orthology)

SACS ANKFY1

4.80e-0522052DOID:0050946 (implicated_via_orthology)
DiseaseJeune thoracic dystrophy

IFT140 DYNC2H1 TTC21B

5.23e-05112053C0265275
DiseaseShort Rib-Polydactyly Syndrome

IFT140 DYNC2H1 TTC21B

8.98e-05132053C0036996
DiseaseSaldino-Noonan Syndrome

IFT140 DYNC2H1 TTC21B

1.14e-04142053C0036069
DiseaseMajewski Syndrome

IFT140 DYNC2H1 TTC21B

1.14e-04142053C0024507
Diseasevisceral:subcutaneous adipose tissue ratio

ELAC2 CNTN6 CACNA1D ZFAT CNTNAP2

1.29e-04702055EFO_0004767
Diseasefactor VIII measurement, coronary artery disease

TDRD15 STAB2 DYNC2H1 APOB EDNRA SMAD3

1.42e-041132056EFO_0001645, EFO_0004630
DiseaseEpidermolytic palmoplantar keratoderma Vorner type

KRT9 KRT16

1.43e-0432052C2931735
Diseasecomplement C5 measurement

F13B C5

1.43e-0432052EFO_0020278
DiseaseEpidermolytic palmoplantar keratoderma of Vorner

KRT9 KRT16

1.43e-0432052C0343110
DiseaseKeratoderma, Palmoplantar, Epidermolytic

KRT9 KRT16

1.43e-0432052C1721006
DiseaseAutosomal Dominant Lateral Temporal Lobe Epilepsy

RELN DEPDC5

1.43e-0432052C1838062
DiseaseJeune thoracic dystrophy

DYNC2H1 TTC21B

2.86e-0442052cv:C0265275
Diseasechildhood aggressive behaviour measurement

DLEC1 CNTN4 TTC21B ASB4 ANKRD7

3.99e-04892055EFO_0007663
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

TDRD15 APOB ZNF528

4.62e-04222053EFO_0009312
DiseaseQRS duration, response to sulfonylurea

MDN1 LRFN5 LRRC63

5.28e-04232053EFO_0005055, EFO_0007922
Diseasenephrotic syndrome (biomarker_via_orthology)

APOB ECE1 EDNRA

6.01e-04242053DOID:1184 (biomarker_via_orthology)
Diseasecoronary artery disease

TDRD15 IFT140 TRPM7 RPTOR DLEC1 C5 RHOF SOX6 DYNC2H1 HSF2BP APOB ANKRD55 EDNRA RSBN1 OSM CMIP ZNF100 SMAD3 PMFBP1

7.07e-04119420519EFO_0001645
DiseaseAganglionic megacolon

ECE1 EDNRB

7.07e-0462052cv:C0019569
DiseaseDNA methylation

LRP1B CNTN6 MDN1 PXDNL LRFN5 PCDH10 DNHD1 CNTN4 ZFAT FRY CNTNAP2 TNR PMFBP1

7.24e-0465620513GO_0006306
Diseasefibrinogen measurement, coronary artery disease

TDRD15 DYNC2H1 CHD9 EDNRA NLRP3 SMAD3

7.48e-041542056EFO_0001645, EFO_0004623
Diseasemean arterial pressure

IP6K1 TTBK1 PXDNL RPTOR SOX6 CACNA1D MMS22L TFAP2D HIPK2 ASB15 CMIP

7.87e-0449920511EFO_0006340
DiseaseCraniofacial Abnormalities

FZD4 CNTN4 ANXA1 ECE1 EDNRA SMAD3

8.00e-041562056C0376634
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

RGS22 C5 ANKRD55 RSBN1

9.78e-04632054EFO_0000685, EFO_0007791, EFO_0009459
DiseaseHereditary Autoinflammatory Diseases

NLRP3 TNFRSF1A

9.86e-0472052C0751422
Diseasepulmonary hypertension (is_marker_for)

TRPC3 TRPC6 EDNRA EDNRB

1.04e-03642054DOID:6432 (is_marker_for)
Diseasecoronary artery disease, factor VII measurement

TDRD15 DYNC2H1 APOB EDNRA SMAD3

1.09e-031112055EFO_0001645, EFO_0004619
Diseaseserum IgG glycosylation measurement

LRP1B ALKBH8 USP15 STAB2 EFCAB6 NAA50 ANKRD55 ABCC6 FRY CNTNAP2 PLCH1

1.15e-0352320511EFO_0005193
DiseaseIntellectual Disability

CDK16 ATP8A2 ACY1 CSDE1 ALKBH8 SACS RNASEH2B SYNE1 FRY PUM1

1.21e-0344720510C3714756
Diseasecarotid artery intima media thickness

TDRD15 LRRK2 LRP1B DLEC1 METTL16 UACA DYNC2H1 APOB EDNRA CNTNAP2

1.28e-0345020510EFO_0007117
DiseaseHirschsprung Disease

RELN ECE1 EDNRB

1.29e-03312053C0019569
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 APOB

1.31e-0382052EFO_0008589, EFO_0008595
Diseaseintelligence, specific language impairment, dyslexia

CCDC136 PMFBP1

1.31e-0382052EFO_0004337, EFO_0005424, EFO_1001510
Diseaseautoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis

LRRK2 ANKRD55 RSBN1 SMAD3

1.45e-03702054EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
Diseaseage at onset, coronary stenosis

DLEC1 PLD1

1.67e-0392052EFO_0004847, MONDO_0006715
DiseaseVasodilators used in cardiac diseases use measurement

DYNC2H1 APOB EDNRA

1.69e-03342053EFO_0009926
Diseasepack-years measurement, systolic blood pressure

LRP1B CNTN4 FRY

1.69e-03342053EFO_0006335, EFO_0006526
DiseaseAutoinflammatory disorder

RNASEH2B NLRP3 TNFRSF1A

1.84e-03352053C3860213
DiseaseSarcomatoid Renal Cell Carcinoma

LRRK2 ACY1 LRP1B DNHD1 ASB15

2.04e-031282055C1266043
DiseaseChromophobe Renal Cell Carcinoma

LRRK2 ACY1 LRP1B DNHD1 ASB15

2.04e-031282055C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

LRRK2 ACY1 LRP1B DNHD1 ASB15

2.04e-031282055C1266044
DiseasePapillary Renal Cell Carcinoma

LRRK2 ACY1 LRP1B DNHD1 ASB15

2.04e-031282055C1306837
DiseaseRenal Cell Carcinoma

LRRK2 ACY1 LRP1B DNHD1 ASB15

2.04e-031282055C0007134
Diseaseresponse to hydrochlorothiazide, diastolic blood pressure change measurement

ZDHHC2 TTC6

2.08e-03102052EFO_0005202, EFO_0006945
Diseaseuveitis (implicated_via_orthology)

ANXA1 TNFRSF1A

2.54e-03112052DOID:13141 (implicated_via_orthology)
Diseasecomparative body size at age 10, self-reported

RELN LRP1B FOCAD TTBK1 RPTOR GCN1 CACNA1D ECE1 CMIP

2.82e-034202059EFO_0009819
Diseasespecific language impairment, dyslexia

CCDC136 PMFBP1

3.03e-03122052EFO_0005424, EFO_1001510
Diseasenicotine dependence (implicated_via_orthology)

TRPC3 TRPC6

3.03e-03122052DOID:0050742 (implicated_via_orthology)
Diseaserenal fibrosis (biomarker_via_orthology)

ECE1 EDNRA

3.03e-03122052DOID:0050855 (biomarker_via_orthology)
Diseaseage at menarche

TRPC6 NR6A1 LRP1B PRDM2 RPTOR USP49 TFAP2D ANXA1 MSH5 CMIP MAPK3

3.09e-0359420511EFO_0004703
Diseasefatty acid measurement, fetal genotype effect measurement, breast milk measurement

ATP8A2 DIAPH3

3.56e-03132052EFO_0005110, EFO_0007959, EFO_0009092
Diseasemale infertility (implicated_via_orthology)

KIT PMFBP1

3.56e-03132052DOID:12336 (implicated_via_orthology)
DiseaseNephronophthisis

ATXN10 TTC21B

3.56e-03132052C0687120
Diseasegallbladder cancer (is_implicated_in)

LRP1B APOB

3.56e-03132052DOID:3121 (is_implicated_in)
DiseaseMultiple Sclerosis

NLRP3 RBPJ TNFRSF1A

3.78e-03452053C0026769
DiseaseMultiple Sclerosis, Acute Fulminating

NLRP3 RBPJ TNFRSF1A

3.78e-03452053C0751324
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

LRRK2 ACY1 LRP1B DNHD1 ASB15

3.82e-031482055C0279702
Diseaseresting heart rate

IP6K1 KLHL42 CACNA1D KRT9 DSP

3.93e-031492055EFO_0004351
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

ATP8A2 DIAPH3

4.14e-03142052EFO_0005110, EFO_0005939, EFO_0009092
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 APOB

4.14e-03142052EFO_0004611, EFO_0008589
Diseaselow density lipoprotein triglyceride measurement

TDRD15 APOB

4.75e-03152052EFO_0009946
DiseaseAganglionosis, Colonic

ECE1 EDNRB

4.75e-03152052C0085758
Diseaseglycerol-3-phosphate measurement

ECE1 CNTNAP2

4.75e-03152052EFO_0010488
DiseaseAganglionosis, Rectosigmoid Colon

ECE1 EDNRB

4.75e-03152052C1257840
Diseaseresponse to statin, LDL cholesterol change measurement

TDRD15 APOB

4.75e-03152052EFO_0007804, GO_0036273
Diseaseunipolar depression, bipolar disorder

PXDNL LRFN5 SOX6 SYNE1 PMFBP1

4.77e-031562055EFO_0003761, MONDO_0004985
Diseasecardiovascular disease

TDRD15 SOX6 CACNA1D TFAP2D HIPK2 HSF2BP APOB CMIP PCNX1

4.88e-034572059EFO_0000319
DiseaseCrohn Disease

LRRK2 NLRP3 SMAD3

5.09e-03502053C0010346
DiseaseKeratoderma, Palmoplantar

KRT9 KRT14

5.41e-03162052C4551675
Diseasetriglycerides to total lipids in very large VLDL percentage

TDRD15 APOB CMIP

6.00e-03532053EFO_0022340
Diseasecholesteryl esters to total lipids in very large VLDL percentage

TDRD15 APOB CMIP

6.00e-03532053EFO_0022258
Diseasesquamous cell lung carcinoma

TRPC3 ELAC2 VARS1 MSH5 FRY

6.03e-031652055EFO_0000708
DiseaseAstrocytosis

MAPK3 TNR

6.10e-03172052C3887640
DiseaseCongenital Intestinal Aganglionosis

ECE1 EDNRB

6.10e-03172052C3661523
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

TDRD15 APOB

6.10e-03172052EFO_0022232
DiseaseGliosis

MAPK3 TNR

6.10e-03172052C0017639
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

OGT ADAMTS8 EDNRB MAPK3

6.26e-031052054DOID:9352 (implicated_via_orthology)
Diseasecholesterol to total lipids in very large VLDL percentage

TDRD15 APOB CMIP

6.32e-03542053EFO_0022244
Diseasepulmonary hypertension (implicated_via_orthology)

ECE1 EDNRA EDNRB

6.32e-03542053DOID:6432 (implicated_via_orthology)
Diseaseplatelet component distribution width

STARD8 LRRK2 C2CD5 TXK RIN2 DLEC1 USP15 RHOF USP49 SYNE1 TEX11 EDNRA

6.80e-0375520512EFO_0007984
Diseasesyndrome (implicated_via_orthology)

ZDHHC2 ATAD3B

6.83e-03182052DOID:225 (implicated_via_orthology)
DiseaseHypertrophy

TRPC6 MAPK3

6.83e-03182052C0020564
Diseasecaudal middle frontal gyrus volume measurement

ZFAT FRY

6.83e-03182052EFO_0010290
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

TDRD15 APOB

6.83e-03182052EFO_0008317, EFO_0008589

Protein segments in the cluster

PeptideGeneStartEntry
QEAQMQEDRRCTGYI

USP26

866

Q9BXU7
LLGKAQCLEMRQNYS

TTC21B

181

Q7Z4L5
QCLEMRQNYSGALET

TTC21B

186

Q7Z4L5
VQGHVQLRIMENYCL

TTC21B

1116

Q7Z4L5
GYILMARNKNNACGI

CTSK

306

P43235
QGVEYQAAMECLQKA

AKAP9

3071

Q99996
CLMVYNNEVVGKGRN

ADAT2

46

Q7Z6V5
QLRQREVVDLYNGMC

CTHRC1

41

Q96CG8
YLIQGLVNMCQSALQ

TNFAIP1

111

Q13829
ELYMIGCDRSQNLVD

ALKBH8

426

Q96BT7
MDINGCAAIQYVLKV

ASB4

281

Q9Y574
GRMALYQLDQQCRQI

ADAMTS8

441

Q9UP79
CEMTVNTELLGYLQV

ATXN10

311

Q9UBB4
QAQGRMCALYASLAL

GSDMD

461

P57764
MLRLLLNNGYQVEMC

ASB15

431

Q8WXK1
LCNGMRYKLLQEGDI

CMIP

46

Q8IY22
ITIVNLSDAGMYQCL

CNTN4

371

Q8IWV2
EKLNNLRDCAIQYFM

CMTR2

391

Q8IYT2
CTQQNILFMLLKGYE

CAB39

121

Q9Y376
LCVLGQNAQTMAYNI

CSDE1

656

O75534
LEVCGNALMKQYQVQ

GLE1

626

Q53GS7
DYIGINLATMNSCIN

EDNRA

351

P25101
VLDYIGINMASLNSC

EDNRB

366

P24530
NINMQDAYGRTSLCL

ANKRD55

86

Q3KP44
PVNCLQIALRMGNYE

ASB14

386

A6NK59
QLGKFARLVDYMICQ

DNHD1

516

Q96M86
VIQCLKALMNTQYGL

DIAPH3

246

Q9NSV4
NQRRLKVYMNQVCDD

ARMCX3

196

Q9UH62
QGQIKMYINEVCRET

ARMCX6

191

Q7L4S7
GYSCRLVSQNMALIL

ATP8A2

716

Q9NTI2
YSQEAMQRALIGRCQ

ADAT1

336

Q9BUB4
SYRLMQLGCLESVAN

TFAP2D

21

Q7Z6R9
LMERNNLSYDCIGRL

HMGCS1

76

Q01581
GYQLENQKRMICNII

RAG2

276

P55895
LSLQYMIRNEDGQIC

RAD1

251

O60671
RRCDMCSNYEKQLQG

RABEP1

531

Q15276
VDGTCVAVNNKYRLM

RIC1

251

Q4ADV7
LRQDRGGMIQTCEQY

PTPN5

531

P54829
QQMIISRYLLSVCGF

NPIPB12

481

F8W0I5
IILMIRYKVCNNNGQ

LRFN5

546

Q96NI6
GIQMRISRVSCLYNE

RADX

126

Q6NSI4
QKMYGISLCQAILDE

ANXA1

316

P04083
AYMKGNANLCRAIVR

ANKFY1

1051

Q9P2R3
MEDYLQGCRAALQES

PRUNE1

1

Q86TP1
EFICQRLMQGYQIIV

DEPDC5

801

O75140
TRYNQETPMEICLNG

PLD3

271

Q8IV08
IYNRNCLIELVNCQM

KIAA0100

1571

Q14667
QEYMQNCEQLLLGSS

MDN1

3156

Q9NU22
LCYNRQMELGAMISQ

GPR82

186

Q96P67
RKYIFNCLDDMAQVN

HIPK2

466

Q9H2X6
YLQKNRMSCQGIESF

LRP1B

1866

Q9NZR2
IEQRCMRYNLSAGTI

MIS18BP1

661

Q6P0N0
LTYDRLVNGMLQCVA

KIT

416

P10721
TKNRYCGQLQMIQEQ

KRT9

401

P35527
KEMGQNLRETVSYCL

MTUS1

331

Q9ULD2
ENSLEETKGRYCMQL

KRT14

356

P02533
ETKGRYCMQLAQIQE

KRT14

361

P02533
NLQYMVKACQVGSEE

MMS22L

1136

Q6ZRQ5
YITGSILRMQCDRGQ

F13B

626

P05160
SQNQKRLYIMTLGCL

NAA50

66

Q9GZZ1
ETMQEGLRLCADRNY

PCNX1

1721

Q96RV3
EMLYQCQGHRNVLEL

MKNK2

131

Q9HBH9
QNICEVGFEYMNREL

PEX2

181

P28328
AQDLIQCAMVKGYLT

PGLYRP4

326

Q96LB8
VEQGCQILDSLSYMR

FBXO39

176

Q8N4B4
LEETKGRYCMQLSQI

KRT16

361

P08779
KNNMILCQTDYEEGL

LMO3

121

Q8TAP4
DYLKNVMLERACDQN

LRRK2

706

Q5S007
VEGQNRDLMNQLCTY

METTL16

536

Q86W50
RDLMNQLCTYIRNQI

METTL16

541

Q86W50
ELLTNCYIMVQGNTV

KRR1

176

Q13601
DKQYLDCCGNLMQTL

TUBGCP5

696

Q96RT8
GMRQAAAIILNIYCS

GCN1

2166

Q92616
QEDLNCIINMKARNY

MAPK3

266

P27361
MTNLAIVNCQVYGRN

LRRC63

311

Q05C16
AQLAYSILECQIQGM

PCDH10

496

Q9P2E7
KYIQGLKNNMNCEAR

C17orf75

171

Q9HAS0
IIQRMLSCYQQGIAL

DZIP3

576

Q86Y13
FGIMLQLYAQICRIV

GPR3

206

P46089
LNGCINPVLYAAMNR

GPR84

361

Q9NQS5
YRIQGGQVDIDCLSM

RELN

1621

P78509
SLQCYRINLQMRLGG

INO80B

331

Q9C086
QMYGCRVIQKALEFI

PUM1

931

Q14671
KGEACMLLRIYQRNT

PATE3

46

B3GLJ2
QILLYNGDVDMACNF

CTSA

391

P10619
MIRNTRESDQGVYQC

PXDNL

291

A1KZ92
LMRGTILRCTKYNQE

CCDC105

356

Q8IYK2
QMEKLRNELAAYLCG

C6orf132

466

Q5T0Z8
QILYNRTMVQLGICA

EIF3C

606

Q99613
DPIRISMCQNLGYNV

FZD4

46

Q9ULV1
LKDCQQLAMLYNNRE

DNAH1

986

Q9P2D7
KALELYEQLCQRMGV

DYNC2H1

1961

Q8NCM8
LDFNIGQNRMLLCQE

EFCAB5

1266

A4FU69
GQNRMLLCQEYKDLQ

EFCAB5

1271

A4FU69
VQILYNRTMVQLGIC

EIF3CL

606

B5ME19
IANYLMEQIQDDCTG

APOB

466

P04114
YNRRNCILADEMGLG

CHD9

876

Q3L8U1
LMCSAYRNQLLNIFV

GNPAT

476

O15228
NLSINNDLNLRYCMG

EFCAB6

236

Q5THR3
NDLNLRYCMGNQEVS

EFCAB6

241

Q5THR3
DLKQYLDDCGNIINM

CDK16

246

Q00536
RLYGAILQMRSCNKE

CHKA

146

P35790
SLLEKQRIACQQMGY

CPHXL2

136

A0A1W2PPK0
ANQLMQYDQCLTKGA

GALNT7

576

Q86SF2
CTNAELVKGRQYLIM

C5

1606

P01031
MGQPCDAYQKRLLQL

DSP

131

P15924
VLKLQQRCRMYGAET

HAP1

391

P54257
LVCQRMLNQGFLKVE

FBXO28

96

Q9NVF7
ELCYEGIVDSQLRNM

ANKRD7

216

Q92527
RVYGAQNEMCLATQQ

APPL2

46

Q8NEU8
TDQDIGMYQCLATNL

CNTN6

91

Q9UQ52
IQFYNQLQVCVGVML

DNAH14

1411

Q0VDD8
LGVRVCGMQVYQLDT

IP6K1

256

Q92551
CMESINYNGVNITDL

CNTNAP2

336

Q9UHC6
LINTTDRCLLNNYMI

ECE1

381

P42892
YLCRNNTIQTMEELL

FRY

1481

Q5TBA9
DRINAQYLEVKCGAM

HAUS4

261

Q9H6D7
QQRVREVYLMNLSGC

DLEC1

1651

Q9Y238
GNIGVQMLVDLSQCY

SACS

3936

Q9NZJ4
LLSYAAALQCMGRQD

POLRMT

296

O00411
KYQEALQLCLGQNMS

IFT140

1151

Q96RY7
VLEMRGNAVVGYLQC

C2CD5

211

Q86YS7
CRNYFNLLDMLVVGV

CACNA1D

951

Q01668
SELPCQLVQMNYVGN

SERPINA6

246

P08185
IKENCMRVGLVAYSN

COL6A6

261

A6NMZ7
MRLNFGEEIQQLCLE

FOCAD

1416

Q5VW36
TALLGNDNYKQIAMC

KIFAP3

391

Q92845
GRMCYAIIQAESKQA

MIF4GD

56

A9UHW6
YDRTCNNEVVKMQRL

MED6

41

O75586
CMLQKVLLNEYNGID

PRDM2

886

Q13029
KEMQDVQGALQCYTR

OGT

406

O15294
GTMQGVYEQCEALLR

OTOG

341

Q6ZRI0
MYVLLRMACSNIQIN

OR1D2

181

P34982
ETLLMYQLQCQVLAR

MSH5

501

O43196
QSCLLQNLGLSEMYF

NLRP3

996

Q96P20
CMKAINFLNQDIRGL

NR6A1

391

Q15406
TCRLYRGNDQIMTNL

PMFBP1

876

Q8TBY8
LVCNSRILSYMGELQ

RTKN

76

Q9BST9
YLKDEQLCRLNLGMQ

RSBN1

311

Q5VWQ0
LCAYMSQGRDINLDV

VARS1

926

P26640
QQLLQQAEYCTEMGA

HSF2BP

111

O75031
MQGLSACEQIRAALY

RHOF

156

Q9HBH0
QYVQCVAGCLQLMLR

ATP6V1H

196

Q9UI12
VAGCLQLMLRVNEYR

ATP6V1H

201

Q9UI12
CCGLIDLMREYQNLK

SYNE1

2081

Q8NF91
YCQLGRNNKDLEMIE

TDRD15

981

B5MCY1
CLQTLFEQQNMYRLK

ABCC6

361

O95255
SYQELLQRKGALMCL

ABCC6

836

O95255
NYRTMCRGENSILGQ

PLD1

846

Q13393
INVNYNIMCLSREEG

RGS22

106

Q8NE09
CINAGENMKYGEQLL

NEXMIF

186

Q5QGS0
EIGREIQQLSMAGCY

FBXL18

91

Q96ME1
DMVITYGLDQLENCQ

SMG1

476

Q96Q15
YMLCTDGQQLLRQVL

ESRP2

126

Q9H6T0
LRNNIYCMAQLLDNS

OSM

146

P13725
QAMRYLRSQCLDQVG

STARD8

591

Q92502
TAMEYLNGQDCSLLL

RPTOR

1071

Q8N122
QQRMESENNKLCSLY

SOX6

76

P35712
CQYRNINRKLSAAGM

HTR7

401

P34969
LCELQLLYQGMQEEQ

CCDC136

611

Q96JN2
IYARGAQDMKCVSIQ

ACY1

106

Q03154
ACVQDAVQQYRQKMR

ATAD3B

556

Q5T9A4
ECSINGMKYQEINGR

ATP11B

421

Q9Y2G3
AMIDCLQGKQLYAVS

RNF17

1576

Q9BXT8
EVGLQVCRQGYNMLN

PRPF8

491

Q6P2Q9
LECMYANLQLQTQLA

TSACC

66

Q96A04
CLNEDYTMGLKNARN

SKA3

231

Q8IX90
MVCGIQEAAENYRKL

TRIML2

51

Q8N7C3
RVCKLIYTVMENNSG

RIN2

676

Q8WYP3
CLDSAQQGLYRKVML

ZNF100

51

Q8IYN0
VMLENYRNLASLGLC

ZFP28

131

Q8NHY6
MVENYRNLVFLGICL

ZNF880

36

Q6PDB4
QMNTSLCERIRKVYG

ZFAT

726

Q9P243
CGRNEKFNYVVMQLQ

TTBK1

96

Q5TCY1
VMLENYSNLVTVGCQ

ZNF568

76

Q3ZCX4
LAYEGRAVVCLQMGN

TTC6

316

Q86TZ1
NRYLFNCGEGVQRLM

ELAC2

81

Q9BQ52
RDISLIKQYVQRQCM

REV3L

2881

O60673
GEGAIYLFNMCLQQL

RNASEH2B

46

Q5TBB1
SLYLACALMVRGNVQ

TUBE1

341

Q9UJT0
VNQGFEAVYQLTRMC

SMAD3

356

P84022
DALRCVNNYQGMLKV

TIPRL

71

O75663
VNNYQGMLKVACAEE

TIPRL

76

O75663
LNGELSQKLQVYCDM

TNR

1156

Q92752
RNLGNTCYMNSILQV

USP49

256

Q70CQ1
VYLTELKLCENGNMN

USP15

131

Q9Y4E8
VMLENYRNLVSVGLC

ZNF470

51

Q6ECI4
PQLMRDIQVNLGYLC

NUP188

1471

Q5SRE5
RNMACCYLNLQQLDK

TEX11

461

Q8IYF3
CYGNIMERLRELNTE

STAB2

361

Q8WWQ8
GYAQQDTQEFLRCLM

USP20

226

Q9Y2K6
QSKVDMYARVLQEGC

PLCH1

326

Q4KWH8
GCQLVALNYQSEGRM

PLCH1

676

Q4KWH8
EMQQLNLEGKNYCTA

RBPJ

111

Q06330
LECTMRGVLREQYLQ

ZNFX1

736

Q9P2E3
RDKQNRTALMLGCEY

UACA

196

Q9BZF9
ELQRFQTGEKMYECN

ZNF677

201

Q86XU0
RTLYQEVMLENCGLL

ZNF264

36

O43296
QNSFQIGMLRRYEEC

ZNF253

91

O75346
IVTEFMENGCLLNYL

TXK

341

P42681
MENGCLLNYLRENKG

TXK

346

P42681
MNSGILQVFQRELIC

TRIM51G

1

A0A3B3IT33
SLLQNDAYNDCLKGM

ZUP1

371

Q96AP4
VMLENYFNLISVGCQ

ZNF484

36

Q5JVG2
VMLENYRNLVSLGIC

ZNF528

36

Q3MIS6
AYAIQLCIVSMENTG

ZDHHC2

36

Q9UIJ5
LRGAAQCYLLQTAMN

TARBP1

526

Q13395
MNSGILQVFQRELIC

TRIM49B

1

A6NDI0
VNCVDYMGQNALQLA

TRPC6

126

Q9Y210
VENLQRLCYMGLLQF

GTF3C1

966

Q12789
QNGRCLREAQYSMLA

TNFRSF1A

391

P19438
SIQAVRLNLMQNYRC

ZNF106

1801

Q9H2Y7
QMCIQIKEVGDRVNY

TRPM7

1206

Q96QT4
RNLGNTCYMNSVLQV

USP44

276

Q9H0E7
TLYQEVMLENCGLLV

ZNF805

36

Q5CZA5
GYSQQDAQEFLRCLM

USP33

266

Q8TEY7
NCVDYMGQNALQLAV

TRPC3

56

Q13507
GVFVNIQYTLRCDMK

VPS26C

111

O14972
QKNLYREVMQETCRN

ZNF669

111

Q96BR6
VNCMQLGVESNGRYI

VPS13D

961

Q5THJ4
GRLESLLNYQTMVCD

GLDC

171

P23378
LLNYQTMVCDITGLD

GLDC

176

P23378
LLSQVRLNNCLEMYR

KLHL42

121

Q9P2K6
GYMIVKCRGQQEITN

MX2

321

P20592
RKVQVQDRGQYMCTA

MXRA5

1916

Q9NR99
RKGMQIRCNISYLEE

MYO5C

1601

Q9NQX4