Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	vitamin D response element binding	TCF3 VDR	2.31e-05	3	56	2	GO:0070644
GeneOntologyMolecularFunction	kinase binding	RAF1 TCF3 ABI2 RBBP6 PER1 GRB14 GOLGA8B ZC3HC1 RAD54L2 DNAJB2 FAF1	6.64e-05	969	56	11	GO:0019900
GeneOntologyMolecularFunction	GTPase binding	RAF1 PLEKHG1 PTPRN ABI2 DOCK7 FGD5	5.00e-04	360	56	6	GO:0051020
GeneOntologyMolecularFunction	protein kinase binding	RAF1 TCF3 RBBP6 GRB14 GOLGA8B ZC3HC1 RAD54L2 DNAJB2 FAF1	6.68e-04	873	56	9	GO:0019901
Domain	FA58C	CNTNAP3B CNTNAP3	1.79e-03	21	56	2	SM00231
Domain	FA58C_3	CNTNAP3B CNTNAP3	1.79e-03	21	56	2	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3	1.79e-03	21	56	2	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3	1.79e-03	21	56	2	PS01286
Domain	PAS_fold_3	PER1 NPAS2	2.15e-03	23	56	2	IPR013655
Domain	PAS_3	PER1 NPAS2	2.15e-03	23	56	2	PF08447
Domain	F5_F8_type_C	CNTNAP3B CNTNAP3	2.34e-03	24	56	2	PF00754
Domain	FA58C	CNTNAP3B CNTNAP3	2.34e-03	24	56	2	IPR000421
Domain	PAS-assoc_C	PER1 NPAS2	2.34e-03	24	56	2	IPR000700
Domain	PAC	PER1 NPAS2	2.74e-03	26	56	2	IPR001610
Domain	PAC	PER1 NPAS2	2.74e-03	26	56	2	SM00086
Domain	PAC	PER1 NPAS2	2.74e-03	26	56	2	PS50113
Domain	DnaJ_domain_CS	DNAJC21 DNAJB2	2.95e-03	27	56	2	IPR018253
Domain	ZnF_U1	DNAJC21 ZNF318	3.40e-03	29	56	2	SM00451
Domain	Znf_U1	DNAJC21 ZNF318	3.40e-03	29	56	2	IPR003604
Domain	SH3	SHANK1 ABI2 SRGAP3 MACF1	3.99e-03	216	56	4	PS50002
Domain	FIBRINOGEN_C_1	CNTNAP3B CNTNAP3	4.13e-03	32	56	2	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP3B CNTNAP3	4.13e-03	32	56	2	IPR002181
Domain	PAS	PER1 NPAS2	4.13e-03	32	56	2	SM00091
Domain	FIBRINOGEN_C_2	CNTNAP3B CNTNAP3	4.13e-03	32	56	2	PS51406
Domain	SH3_domain	SHANK1 ABI2 SRGAP3 MACF1	4.26e-03	220	56	4	IPR001452
Domain	PAS	PER1 NPAS2	4.66e-03	34	56	2	IPR000014
Domain	PAS	PER1 NPAS2	4.66e-03	34	56	2	PS50112
Domain	PH	PLEKHG1 PHLPP1 GRB14 FGD5	4.91e-03	229	56	4	PF00169
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP3	5.79e-03	38	56	2	PS50025
Domain	Laminin_G_2	CNTNAP3B CNTNAP3	6.40e-03	40	56	2	PF02210
Domain	LamG	CNTNAP3B CNTNAP3	7.71e-03	44	56	2	SM00282
Domain	DnaJ	DNAJC21 DNAJB2	9.12e-03	48	56	2	PF00226
Domain	DNAJ_1	DNAJC21 DNAJB2	9.49e-03	49	56	2	PS00636
Domain	DNAJ_2	DNAJC21 DNAJB2	9.49e-03	49	56	2	PS50076
Domain	DnaJ	DNAJC21 DNAJB2	9.49e-03	49	56	2	SM00271
Domain	-	DNAJC21 DNAJB2	9.49e-03	49	56	2	1.10.287.110
Domain	PH	PLEKHG1 PHLPP1 GRB14 FGD5	9.62e-03	278	56	4	SM00233
Domain	PH_DOMAIN	PLEKHG1 PHLPP1 GRB14 FGD5	9.74e-03	279	56	4	PS50003
Pathway	REACTOME_RHO_GTPASE_CYCLE	PLEKHG1 ABI2 RBBP6 SRGAP3 DOCK7 GOLGA8B FGD5 PEAK1	4.62e-05	439	43	8	MM15595
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLEKHG1 SRGAP3 STXBP5 PDE4DIP DOCK7 ACIN1 MACF1 C2CD2L	2.86e-07	407	56	8	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 RAF1 PLEKHG1 ZFP36L1 DOCK7 KDM3B ANKRD17 MACF1 WWTR1 PEAK1	1.04e-06	861	56	10	36931259
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	RAF1 RBBP6 AKNAD1 DOCK7 ANKRD17 CARD11	1.08e-06	208	56	6	33230847
Pubmed	A human MAP kinase interactome.	SHANK1 CEP350 RBBP6 ANKRD17 MACF1 WWTR1 MBD5 PNISR	1.08e-06	486	56	8	20936779
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	CEP350 PDE4DIP PER1 MACF1	2.08e-06	56	56	4	9455484
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	2.55e-06	2	56	2	31150793
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	2.55e-06	2	56	2	26807827
Pubmed	Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.	ERN1 PER1	2.55e-06	2	56	2	23752693
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RBBP6 DOCK7 KDM3B ACIN1 WWTR1 ZNF318 PEAK1 RSBN1L	2.68e-06	549	56	8	38280479
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 ATXN2 ABI2 SRGAP3 PDE4DIP DOCK7 GOLGA8B ANKRD17 MACF1 ZNF318	2.84e-06	963	56	10	28671696
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 CEP350 PDE4DIP MACF1 RAD54L2 HSD17B4 DNAJB2 PNISR CCDC85A RSBN1L FAF1	5.42e-06	1285	56	11	35914814
Pubmed	Long-term Fgf23 deficiency does not influence aging, glucose homeostasis, or fat metabolism in mice with a nonfunctioning vitamin D receptor.	DOCK7 VDR	7.63e-06	3	56	2	22294750
Pubmed	Circadian genes and risk of prostate cancer: Findings from the EPICAP study.	PER1 NPAS2	7.63e-06	3	56	2	30665264
Pubmed	Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis.	PER1 NPAS2	7.63e-06	3	56	2	17264841
Pubmed	Impact of Ataxin-2 knock out on circadian locomotor behavior and PER immunoreaction in the SCN of mice.	ATXN2 PER1	7.63e-06	3	56	2	27791392
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAF1 DOCK7 KDM3B DNAJC21 ANKRD17 RAD54L2 HSD17B4 RSBN1L	9.19e-06	650	56	8	38777146
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 RAF1 KMT5B RBBP6 PER1 ANKRD17 MACF1 ZNF318 RSBN1L C2CD2L	1.04e-05	1116	56	10	31753913
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	TCF3 STXBP5 SHB WWTR1 RAD54L2	1.08e-05	180	56	5	35198878
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SHANK1 ABI2 SRGAP3 PDE4DIP DOCK7 PER1 MACF1 PEAK1 DNAJB2 C2CD2L	1.24e-05	1139	56	10	36417873
Pubmed	eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth.	WWTR1 PEAK1	1.52e-05	4	56	2	28381547
Pubmed	Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes.	PER1 NPAS2	1.52e-05	4	56	2	19829696
Pubmed	Grb10 and active Raf-1 kinase promote Bad-dependent cell survival.	RAF1 GRB14	1.52e-05	4	56	2	17535812
Pubmed	PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.	RAF1 PHLPP1	1.52e-05	4	56	2	24530606
Pubmed	Vitamin D analog EB1089 inhibits aromatase expression by dissociation of comodulator WSTF from the CYP19A1 promoter-a new regulatory pathway for aromatase.	TCF3 VDR	1.52e-05	4	56	2	23085504
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SHANK1 ABI2 PDE4DIP MACF1 GRID1	1.67e-05	197	56	5	36604605
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP36 ELOA RBBP6 KDM3B ANKRD17 ACIN1 MACF1 ZNF318 RSBN1L	1.71e-05	934	56	9	33916271
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP36 ATXN2 ABI2 RBBP6 DNAJC21 ANKRD17 MACF1 ZNF318 PNISR RSBN1L C2CD2L	2.26e-05	1497	56	11	31527615
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	USP36 RBBP6 MACF1 CARD11 STK31 PNISR	2.52e-05	361	56	6	26167880
Pubmed	Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene.	TCF3 VDR	2.54e-05	5	56	2	17426122
Pubmed	Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth.	WWTR1 FOSL1	2.54e-05	5	56	2	26258633
Pubmed	Correlation between circadian gene variants and serum levels of sex steroids and insulin-like growth factor-I.	PER1 NPAS2	2.54e-05	5	56	2	18990770
Pubmed	Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators.	PER1 NPAS2	2.54e-05	5	56	2	18316400
Pubmed	Altered expressions and splicing profiles of Acin1 transcripts differentially modulate brown adipogenesis through an alternative splicing mechanism.	ERN1 ACIN1	2.54e-05	5	56	2	32629174
Pubmed	Variants in circadian genes and prostate cancer risk: a population-based study in China.	PER1 NPAS2	2.54e-05	5	56	2	17984998
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	USP36 ELOA ZNF318 RAD54L2 HSD17B4	2.97e-05	222	56	5	37071664
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SRGAP3 KDM3B PHLPP1 MACF1 C2CD2L	3.16e-05	225	56	5	12168954
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ABI2 STXBP5 SHB DOCK7 PEAK1 C2CD2L	3.20e-05	377	56	6	38117590
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 USP36 DOCK7 KDM3B MUC16 ZC3HC1 ZNF318 PEAK1	3.30e-05	777	56	8	35844135
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	3.80e-05	6	56	2	34143959
Pubmed	The molecular clock mediates leptin-regulated bone formation.	PER1 NPAS2	3.80e-05	6	56	2	16143109
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CEP350 USP36 ELOA PTPRN ATXN2 ABI2 PHLPP1 PEAK1 HSD17B4	4.23e-05	1049	56	9	27880917
Pubmed	The trophoblast clock controls transport across placenta in mice.	PER1 NPAS2	5.32e-05	7	56	2	33913482
Pubmed	Transcriptional architecture and chromatin landscape of the core circadian clock in mammals.	PER1 NPAS2	5.32e-05	7	56	2	22936566
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CEP350 KDM3B MUC16 ANKRD17 FGD5 STK31 CCDC85A	7.20e-05	638	56	7	31182584
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ELOA TCF3 ZFP36L1 PER1 WWTR1 FOSL1 VDR NPAS2	7.71e-05	877	56	8	20211142
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ELOA SHB DNAJC21 ACIN1 MACF1 ZNF318 RAD54L2 HSD17B4 STK31 PNISR	9.09e-05	1442	56	10	35575683
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	ELOA RBBP6 ACIN1 ZNF318 RSBN1L	9.37e-05	283	56	5	30585729
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ABI2 SRGAP3 PDE4DIP MACF1	1.05e-04	151	56	4	17043677
Pubmed	HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome.	RAF1 DNAJB2	1.14e-04	10	56	2	15936278
Pubmed	Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.	PER1 NPAS2	1.14e-04	10	56	2	16528748
Pubmed	Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.	PER1 NPAS2	1.14e-04	10	56	2	19934327
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CEP350 ZFP36L1 PDE4DIP DNAJC21 FGD5 ZNF318 MBD5	1.16e-04	689	56	7	36543142
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 PER1 MACF1 PEAK1 MBD5 CCDC85A	1.40e-04	493	56	6	15368895
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 USP36 ATXN2 DOCK7 DNAJC21 ANKRD17 MACF1	1.57e-04	724	56	7	36232890
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	RBBP6 DOCK7 KDM3B ACIN1 ZNF318 PNISR	1.61e-04	506	56	6	30890647
Pubmed	Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.	PER1 NPAS2	1.66e-04	12	56	2	14645221
Pubmed	Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.	ELOA FAF1	1.96e-04	13	56	2	15207703
Pubmed	A Y2H-seq approach defines the human protein methyltransferase interactome.	SRGAP3 PDE4DIP DOCK7 KDM3B FGD5	2.26e-04	342	56	5	23455924
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ELOA RBBP6 KDM3B ANKRD17 ACIN1 ZNF318 PNISR	2.37e-04	774	56	7	15302935
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CEP350 RAF1 TCF3 ZFP36L1 DOCK7 PER1 KDM3B PNISR	2.45e-04	1038	56	8	26673895
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CEP350 TCF3 MACF1	2.56e-04	76	56	3	27542412
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ERN1 PDE4DIP KDM3B MUC16 ZC3HC1 FGD5	2.58e-04	552	56	6	10737800
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	DOCK7 MACF1 FGD5 HSD17B4	2.59e-04	191	56	4	33762435
Pubmed	Voxelwise genome-wide association study (vGWAS).	RBBP6 SHB	2.64e-04	15	56	2	20171287
Pubmed	PER2 variantion is associated with depression vulnerability.	PER1 NPAS2	3.01e-04	16	56	2	19693801
Pubmed	Identification and characterization of proteins interacting with Traf4, an enigmatic p53 target.	PDE4DIP NPAS2	3.01e-04	16	56	2	16969126
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CEP350 RAF1 ELOA ATXN2 DOCK7 GOLGA8B ANKRD17 ACIN1 RSBN1L	3.19e-04	1371	56	9	36244648
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ELOA RBBP6 DOCK7 ACIN1 MACF1 HSD17B4 PNISR NPAS2	3.23e-04	1082	56	8	38697112
Pubmed	Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.	CNTNAP3B CNTNAP3	3.41e-04	17	56	2	26389685
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 DOCK7 MACF1 PEAK1	3.64e-04	209	56	4	36779422
Pubmed	Functional proteomics mapping of a human signaling pathway.	RBBP6 PDE4DIP KDM3B MACF1 DNAJB2 FAF1	3.71e-04	591	56	6	15231748
Pubmed	Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception.	PER1 NPAS2	3.83e-04	18	56	2	15741322
Pubmed	Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.	PER1 NPAS2	3.83e-04	18	56	2	20174623
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	ELOA ANKRD17 ACIN1	4.21e-04	90	56	3	35654790
Pubmed	Spatial regulation of Raf kinase signaling by RKTG.	RAF1 GOLGA8B	4.28e-04	19	56	2	17724343
Pubmed	Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder.	PER1 NPAS2	4.28e-04	19	56	2	20072116
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	ATXN2 DOCK7 KDM3B ACIN1	4.42e-04	220	56	4	24550385
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	ATXN2 RBBP6 KDM3B ACIN1 ZNF318	4.58e-04	399	56	5	35987950
Pubmed	An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar.	ENAM ERN1	4.75e-04	20	56	2	30963569
Pubmed	Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.	FOSL1 VDR	4.75e-04	20	56	2	31291246
Pubmed	Stress-induced NEDDylation promotes cytosolic protein aggregation through HDAC6 in a p62-dependent manner.	DNAJB2 FAF1	4.75e-04	20	56	2	33665565
Pubmed	Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia.	PER1 NPAS2	5.24e-04	21	56	2	19839995
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MACF1 PEAK1 HSD17B4 C2CD2L	5.31e-04	231	56	4	16452087
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CNTNAP3B CNTNAP3	5.76e-04	22	56	2	26494785
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PLEKHG1 MACF1 GRID1	6.24e-04	103	56	3	10574462
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	ELOA ATXN2 RBBP6 DOCK7 ACIN1 ZNF318 PNISR	6.74e-04	922	56	7	27609421
Pubmed	Brain development is impaired in c-fos -/- mice.	GOLGA8B FOSL1	7.46e-04	25	56	2	26143639
Pubmed	PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.	ABI2 GOLGA8B	8.07e-04	26	56	2	32673396
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	USP36 ELOA ATXN2 RBBP6 ACIN1 ZNF318 RSBN1L	8.23e-04	954	56	7	36373674
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ATXN2 MACF1 ZNF318 PEAK1	8.62e-04	263	56	4	34702444
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CEP350 RAF1 ERN1 RBBP6 ACIN1 VDR	8.66e-04	695	56	6	23602568
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ELOA ATXN2 RBBP6 DOCK7 DNAJC21 ANKRD17 ACIN1 RSBN1L	8.66e-04	1257	56	8	36526897
Pubmed	Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.	PDE4DIP MACF1	8.71e-04	27	56	2	18685082
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	RAF1 MACF1 PEAK1 HSD17B4 C2CD2L	9.29e-04	467	56	5	30194290
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	USP36 ACIN1 ZC3HC1 ZNF318	9.63e-04	271	56	4	32433965
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	CNTNAP3B CNTNAP3	1.01e-03	29	56	2	31491374
Pubmed	The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism.	GRB14 HSD17B4	1.01e-03	29	56	2	34175335
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	USP36 TCF3 RBBP6 ACIN1 WWTR1 ZNF318 PNISR FOSL1	1.04e-03	1294	56	8	30804502
Pubmed	Genomic analysis of mouse retinal development.	TCF3 SRGAP3 PDE4DIP KDM3B ACIN1 PNISR NPAS2	1.12e-03	1006	56	7	15226823
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	RAF1 DOCK7 KDM3B FAF1	1.21e-03	288	56	4	23383273
Interaction	RCC1 interactions	RAF1 DNAJC21 ACIN1 WWTR1 MBD5 DNAJB2 FAF1	1.36e-06	201	56	7	int:RCC1
Interaction	YWHAG interactions	CEP350 RAF1 PLEKHG1 ZFP36L1 SHB DOCK7 KDM3B ANKRD17 ACIN1 MACF1 WWTR1 PEAK1 FAF1 C2CD2L	5.65e-06	1248	56	14	int:YWHAG
Interaction	EGLN3 interactions	CEP350 RAF1 TCF3 ZFP36L1 ATXN2 ABI2 SHB DOCK7 KDM3B ANKRD17 ZNF318 PEAK1 RAD54L2 HSD17B4	8.71e-06	1296	56	14	int:EGLN3
Interaction	KHSRP interactions	USP36 RAF1 TCF3 WWTR1 RAD54L2 MBD5 FAF1	2.22e-05	308	56	7	int:KHSRP
Interaction	RAPH1 interactions	ABI2 SRGAP3 PHLPP1 WWTR1	3.00e-05	64	56	4	int:RAPH1
Interaction	YWHAE interactions	RAF1 ELOA ZFP36L1 ABI2 SRGAP3 DOCK7 ANKRD17 ZC3HC1 MACF1 WWTR1 FGD5 PEAK1 FAF1	3.07e-05	1256	56	13	int:YWHAE
Interaction	YWHAH interactions	CEP350 RAF1 PLEKHG1 ZFP36L1 ABI2 DOCK7 KDM3B ANKRD17 MACF1 WWTR1 PEAK1 FAF1	4.01e-05	1102	56	12	int:YWHAH
Interaction	XRCC6 interactions	USP36 RAF1 ELOA RBBP6 ACIN1 FGD5 ZNF318 HSD17B4 MBD5 RSBN1L FAF1	4.13e-05	928	56	11	int:XRCC6
Interaction	SWAP70 interactions	PDE4DIP PHLPP1 WWTR1 FAF1	6.55e-05	78	56	4	int:SWAP70
Interaction	CBX3 interactions	RAF1 ELOA RBBP6 ZC3HC1 MACF1 FGD5 RAD54L2 RSBN1L FAF1	6.66e-05	646	56	9	int:CBX3
Interaction	GOLGA8B interactions	RAF1 GOLGA8B	7.54e-05	5	56	2	int:GOLGA8B
Interaction	EPRS1 interactions	CEP350 RAF1 ATXN2 RBBP6 PHLPP1 HSD17B4 STK31 FAF1	8.10e-05	513	56	8	int:EPRS1
Interaction	TNIK interactions	SHANK1 RAF1 ABI2 SRGAP3 PDE4DIP DOCK7 MACF1	8.54e-05	381	56	7	int:TNIK
Interaction	PDGFRA interactions	RAF1 CNTNAP3B SHB CNTNAP3 GRB14 GRID1 PEAK1	9.11e-05	385	56	7	int:PDGFRA
Interaction	TGM5 interactions	DOCK7 ZC3HC1 PEAK1	9.52e-05	32	56	3	int:TGM5
Interaction	UBAP2 interactions	RAF1 PHLPP1 ANKRD17 WWTR1 NPAS2	1.09e-04	170	56	5	int:UBAP2
Interaction	DHX8 interactions	USP36 ELOA RBBP6 ZNF318 PNISR RSBN1L	1.55e-04	292	56	6	int:DHX8
Interaction	RABEP1 interactions	ELOA ABI2 UBTFL1 WWTR1 FOSL1	1.57e-04	184	56	5	int:RABEP1
Interaction	RNF43 interactions	ATXN2 DNAJC21 MACF1 ZNF318 PEAK1 DNAJB2 FAF1	1.73e-04	427	56	7	int:RNF43
Interaction	CLOCK interactions	SRGAP3 PER1 WWTR1 NPAS2	1.86e-04	102	56	4	int:CLOCK
Interaction	KRT8 interactions	CEP350 RAF1 PLEKHG1 DOCK7 PHLPP1 FGD5 FAF1	2.11e-04	441	56	7	int:KRT8
Interaction	MYH9 interactions	USP36 RAF1 DOCK7 KDM3B PHLPP1 MACF1 AKAP10 FGD5 FAF1	2.14e-04	754	56	9	int:MYH9
Interaction	YWHAQ interactions	CEP350 RAF1 TCF3 ZFP36L1 KMT5B DOCK7 ANKRD17 MACF1 WWTR1 FGD5 PEAK1	2.17e-04	1118	56	11	int:YWHAQ
Interaction	YWHAZ interactions	RAF1 ELOA ZFP36L1 KMT5B ABI2 SRGAP3 DOCK7 ANKRD17 MACF1 WWTR1 PEAK1 FAF1	2.22e-04	1319	56	12	int:YWHAZ
Interaction	ANK3 interactions	RAF1 ABI2 DOCK7 WWTR1 PEAK1	2.37e-04	201	56	5	int:ANK3
Interaction	UBE3C interactions	ELOA PTPRN PDE4DIP CNTNAP3 FAF1	2.54e-04	204	56	5	int:UBE3C
Interaction	STUB1 interactions	RAF1 ELOA TCF3 ERN1 PHLPP1 CARD11 DNAJB2 FAF1	2.60e-04	608	56	8	int:STUB1
Interaction	PCDHAC2 interactions	RAF1 RAD54L2 C2CD2L	2.65e-04	45	56	3	int:PCDHAC2
Cytoband	Ensembl 112 genes in cytogenetic band chr3p25	RAF1 SRGAP3 FGD5	9.18e-04	155	56	3	chr3p25
Cytoband	4q13.3	ENAM ANKRD17	1.22e-03	42	56	2	4q13.3
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG1 PHLPP1 GRB14 FGD5	6.50e-04	206	35	4	682
Coexpression	EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP	SRGAP3 PDE4DIP MTSS1 MACF1 WWTR1 C2CD2L	4.33e-06	200	56	6	M78
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CEP350 ATXN2 SHB KDM3B PHLPP1 ANKRD17 MACF1 AKAP10 WWTR1 PNISR	1.19e-05	856	56	10	M4500
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG1 CNTNAP3B SHB FGD5 CCDC85A	3.05e-06	179	56	5	8f9e538c822940785130297712b75131812a4603
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B MACF1 WWTR1 FGD5	3.14e-06	180	56	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 SHB PER1 FOSL1	3.68e-06	186	56	5	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B SRGAP3 STXBP5 DOCK7 NPAS2	3.78e-06	187	56	5	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG1 CNTNAP3B CNTNAP3 FGD5 CCDC85A	3.98e-06	189	56	5	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 WWTR1 FGD5 CCDC85A	3.98e-06	189	56	5	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 SHB PER1 FOSL1	3.98e-06	189	56	5	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4DIP MTSS1 PER1 MBD5 NPAS2	4.09e-06	190	56	5	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 WWTR1 FGD5 CCDC85A	4.09e-06	190	56	5	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	USP36 PLEKHG1 MTSS1 CARD11 PNISR	4.19e-06	191	56	5	a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PLEKHG1 CNTNAP3B GRID1 FGD5 CCDC85A	4.19e-06	191	56	5	1de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 WWTR1 FGD5 CCDC85A	4.41e-06	193	56	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 WWTR1 FGD5 CCDC85A	4.41e-06	193	56	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	COVID_non-vent-Lymphocytic-B_cell-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PLEKHG1 TCF3 GOLGA8B ZNF318 PNISR	4.41e-06	193	56	5	91955c3773c9729a96e82f240f06b072367970d9
ToppCell	COVID_non-vent-Lymphocytic-B_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PLEKHG1 TCF3 GOLGA8B ZNF318 PNISR	4.41e-06	193	56	5	32d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MACF1 WWTR1 FGD5 CCDC85A	4.52e-06	194	56	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B MTSS1 WWTR1 FGD5	4.52e-06	194	56	5	660535b492445063d965095a50e1e299ce04c50a
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLEKHG1 CNTNAP3B CNTNAP3 CCDC85A NPAS2	4.52e-06	194	56	5	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-immature_B_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PLEKHG1 PDE4DIP MTSS1 CARD11 PNISR	4.64e-06	195	56	5	ecaaa3d071e763c40d05d088fbf9e8ca06f78f47
ToppCell	PCW_10-12-Endothelial-Endothelial_mature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLEKHG1 CNTNAP3B CNTNAP3 CCDC85A NPAS2	4.75e-06	196	56	5	481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5 CCDC85A	4.87e-06	197	56	5	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ATXN2 MACF1 AKAP10 PNISR	2.52e-05	135	56	4	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 FGD5 CCDC85A	3.25e-05	144	56	4	748f4efc59f7afbce6c497524f36d852b8b1d637
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ELOA KMT5B MACF1 ZNF318	4.33e-05	155	56	4	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	USP36 ERN1 PHLPP1 FOSL1	4.78e-05	159	56	4	af137688e06a97ff97bb7def54f0dd164d155b11
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZFP36L1 KMT5B MACF1 ZNF318	4.78e-05	159	56	4	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 WWTR1 CCDC85A	5.79e-05	167	56	4	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ENAM STXBP5 CARD11 PEAK1	6.20e-05	170	56	4	db0ec8b7ecbb4db108fc35c564df4b740f65cc8f
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ENAM STXBP5 CARD11 PEAK1	6.20e-05	170	56	4	88f6804e973863245ca1c7e5e6656d4a8b824da9
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ENAM STXBP5 CARD11 PEAK1	6.20e-05	170	56	4	dad3aaf7d9f7bafdbddee51610f03f2359e587ae
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ELOA KMT5B MACF1 ZNF318	6.34e-05	171	56	4	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHG1 CNTNAP3B MACF1 PEAK1	7.41e-05	178	56	4	ad3de3e03a401dac64431a541899445262246347
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	7.57e-05	179	56	4	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 PHLPP1 WWTR1 FGD5	7.57e-05	179	56	4	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP3 PDE4DIP GRB14 VDR	7.57e-05	179	56	4	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B FGD5 CCDC85A	7.57e-05	179	56	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	USP36 SRGAP3 PDE4DIP CNTNAP3	7.74e-05	180	56	4	ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCell	droplet-Marrow-BM\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF3 PER1 DNAJC21 PNISR	7.90e-05	181	56	4	4169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 WWTR1 FGD5 CCDC85A	7.90e-05	181	56	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTSS1 FGD5 PEAK1 CCDC85A	7.90e-05	181	56	4	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 WWTR1 CCDC85A	8.25e-05	183	56	4	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 MACF1 ZNF318	8.42e-05	184	56	4	b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 CNTNAP3B WWTR1 FGD5	8.60e-05	185	56	4	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2 KMT5B ANKRD17 CARD11	8.60e-05	185	56	4	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Marrow-T-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 MACF1 ZNF318	8.60e-05	185	56	4	e1fd0a807def8c2127194108b1a30c6de7024292
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 CNTNAP3B WWTR1 FGD5	8.60e-05	185	56	4	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2 KMT5B ANKRD17 CARD11	8.60e-05	185	56	4	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 CNTNAP3B WWTR1 FGD5	8.60e-05	185	56	4	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHG1 CNTNAP3B MACF1 PEAK1	8.78e-05	186	56	4	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B FGD5 CCDC85A	8.96e-05	187	56	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	PLEKHG1 WWTR1 FGD5 CCDC85A	8.96e-05	187	56	4	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Immune-B_cell\|World / Lineage, Cell type, age group and donor	ENAM PLEKHG1 MTSS1 CARD11	8.96e-05	187	56	4	795690c6306c366e733279491138d0cd9b469b21
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 CNTNAP3B WWTR1 FGD5	8.96e-05	187	56	4	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B SRGAP3 CNTNAP3 FGD5	9.15e-05	188	56	4	1f40b959777d18ad88d239df8cca304f062ba04c
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 FGD5 CCDC85A	9.15e-05	188	56	4	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.15e-05	188	56	4	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.15e-05	188	56	4	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 MACF1 ZNF318	9.15e-05	188	56	4	1f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 MACF1 ZNF318	9.15e-05	188	56	4	85746f95319e494efdc1bbc24331698688d3a900
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B SRGAP3 CNTNAP3 FGD5	9.15e-05	188	56	4	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.34e-05	189	56	4	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 GRB14 FGD5	9.34e-05	189	56	4	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 WWTR1 FGD5	9.34e-05	189	56	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	PLEKHG1 SRGAP3 WWTR1 NPAS2	9.53e-05	190	56	4	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	PLEKHG1 CNTNAP3B CNTNAP3 FGD5	9.53e-05	190	56	4	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 FGD5 CCDC85A	9.53e-05	190	56	4	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 WWTR1 FGD5 CCDC85A	9.53e-05	190	56	4	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.53e-05	190	56	4	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 WWTR1 FGD5 CCDC85A	9.53e-05	190	56	4	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 MTSS1 MACF1 ZNF318	9.53e-05	190	56	4	ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 WWTR1 FGD5 CCDC85A	9.53e-05	190	56	4	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG1 CNTNAP3B FGD5 CCDC85A	9.73e-05	191	56	4	f663131a4810584c5854bd64ee7991a237b7707f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ELOA KMT5B DNAJC21	9.73e-05	191	56	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.73e-05	191	56	4	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	facs-Marrow-B-cells-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF3 ZFP36L1 MTSS1 CARD11	9.73e-05	191	56	4	e53290441a25d6245a96540445186db22026801c
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PLEKHG1 CNTNAP3 WWTR1 FGD5	9.73e-05	191	56	4	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	PLEKHG1 CNTNAP3B FGD5 CCDC85A	9.73e-05	191	56	4	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ELOA KMT5B DNAJC21	9.73e-05	191	56	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ELOA KMT5B DNAJC21	9.73e-05	191	56	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF3 ZFP36L1 MTSS1 CARD11	9.92e-05	192	56	4	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 WWTR1 FGD5 CCDC85A	9.92e-05	192	56	4	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 WWTR1 FGD5	9.92e-05	192	56	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MACF1 PEAK1 FOSL1 NPAS2	9.92e-05	192	56	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG1 TCF3 ZFP36L1 MTSS1	9.92e-05	192	56	4	446c61c0d6ba89c619efe87ee495951299953981
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CNTNAP3B WWTR1 FGD5	9.92e-05	192	56	4	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 FGD5 CCDC85A	9.92e-05	192	56	4	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF3 ZFP36L1 MTSS1 CARD11	9.92e-05	192	56	4	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 WWTR1 FGD5 CCDC85A	9.92e-05	192	56	4	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP3 PDE4DIP MTSS1 NPAS2	9.92e-05	192	56	4	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B GRID1 FGD5 CCDC85A	9.92e-05	192	56	4	7197e401e563441ab94815f7619e032ebef9e586
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG1 CNTNAP3B FGD5 CCDC85A	9.92e-05	192	56	4	56b021c297a21dff357531f21e2464f85186106d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG1 CNTNAP3B FGD5 CCDC85A	9.92e-05	192	56	4	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANKRD17 MACF1 MBD5 FAF1	9.92e-05	192	56	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG1 MTSS1 PHLPP1 WWTR1	1.01e-04	193	56	4	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 WWTR1 FGD5 CCDC85A	1.01e-04	193	56	4	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 MTSS1 FGD5 CCDC85A	1.01e-04	193	56	4	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	PLEKHG1 CNTNAP3B WWTR1 FGD5	1.01e-04	193	56	4	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHG1 MACF1 FGD5 PEAK1	1.01e-04	193	56	4	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 WWTR1 FGD5 CCDC85A	1.01e-04	193	56	4	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	PLEKHG1 CNTNAP3B WWTR1 FGD5	1.01e-04	193	56	4	2531266bc57339d4e2b22a88817008e32b8c1598
Computational	Neighborhood of MAP4K4	CEP350 ABI2 PDE4DIP KDM3B ANKRD17 MACF1 PEAK1	1.97e-06	172	38	7	GCM_MAP4K4
Drug	Oxethazaine [126-27-2]; Up 200; 8.6uM; PC3; HG-U133A	CEP350 TCF3 SRGAP3 PHLPP1 ZNF318 FAF1 C2CD2L	4.35e-07	195	55	7	1903_UP
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A	CEP350 ELOA TCF3 RBBP6 PHLPP1 MACF1	6.84e-06	192	55	6	1599_DN
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HG-U133A	TCF3 ZFP36L1 KMT5B DNAJB2 PNISR NPAS2	7.26e-06	194	55	6	433_DN
Drug	rofecoxib; Down 200; 10uM; PC3; HG-U133A	ZFP36L1 ATXN2 ZNF318 DNAJB2 FAF1 VDR	7.92e-06	197	55	6	463_DN
Drug	Beta-sistosterol [83-46-5]; Down 200; 9.6uM; HL60; HT_HG-U133A	ZFP36L1 PDE4DIP MTSS1 SHB DNAJB2 FOSL1	7.92e-06	197	55	6	2912_DN
Drug	Acetohexamide [968-81-0]; Down 200; 12.4uM; PC3; HT_HG-U133A	TCF3 SHB RAD54L2 HSD17B4 PNISR NPAS2	8.64e-06	200	55	6	1829_DN
Drug	felodipine; Up 200; 10uM; MCF7; HT_HG-U133A_EA	USP36 ZFP36L1 SHB PER1 FOSL1	5.63e-05	170	55	5	965_UP
Drug	squalane	MTSS1 ACIN1	5.70e-05	5	55	2	CID000008089
Drug	5255229; Up 200; 13uM; MCF7; HT_HG-U133A_EA	ZFP36L1 PDE4DIP SHB RAD54L2 FOSL1	6.12e-05	173	55	5	949_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	KMT5B ACIN1 PNISR FOSL1 NPAS2	6.81e-05	177	55	5	6340_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	KMT5B KDM3B PNISR FOSL1 NPAS2	6.81e-05	177	55	5	7047_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	KMT5B KDM3B RAD54L2 DNAJB2 NPAS2	7.19e-05	179	55	5	6609_DN
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	RBBP6 ANKRD17 ZNF318 PNISR NPAS2	7.57e-05	181	55	5	1791_DN
Drug	staurosporine; Down 200; 1uM; MCF7; HG-U133A	CEP350 ZFP36L1 KMT5B RBBP6 C2CD2L	7.57e-05	181	55	5	312_DN
Drug	NSC 402447	RAF1 PTPRN SHB FOSL1	7.59e-05	93	55	4	CID006437335
Drug	lomustine; Down 200; 100uM; PC3; HT_HG-U133A	MTSS1 WWTR1 PNISR VDR NPAS2	9.06e-05	188	55	5	7050_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	TCF3 ZFP36L1 RBBP6 WWTR1 ZNF318	9.76e-05	191	55	5	1008_DN
Drug	Albendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A	PDE4DIP AKAP10 ZNF318 RAD54L2 PNISR	1.00e-04	192	55	5	3164_DN
Drug	17-AAG; Down 200; 1uM; HL60; HT_HG-U133A	USP36 TCF3 PER1 FOSL1 VDR	1.00e-04	192	55	5	2666_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A	USP36 ZFP36L1 WWTR1 PNISR C2CD2L	1.03e-04	193	55	5	6946_DN
Drug	15d-PGJ2; Up 200; 10uM; MCF7; HG-U133A	RBBP6 SHB AKAP10 NPAS2 C2CD2L	1.03e-04	193	55	5	201_UP
Drug	lomustine; Down 200; 100uM; MCF7; HT_HG-U133A	PDE4DIP MTSS1 PER1 MACF1 VDR	1.05e-04	194	55	5	7089_DN
Drug	Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A	USP36 ZFP36L1 SRGAP3 FOSL1 C2CD2L	1.05e-04	194	55	5	7051_UP
Drug	Xylazine [7361-61-7]; Down 200; 18.2uM; MCF7; HT_HG-U133A	TCF3 ZFP36L1 PDE4DIP WWTR1 RAD54L2	1.08e-04	195	55	5	4147_DN
Drug	Securinine [5610-40-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A	TCF3 PDE4DIP AKAP10 DNAJB2 C2CD2L	1.08e-04	195	55	5	3470_DN
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	PDE4DIP SHB ZNF318 RAD54L2 FOSL1	1.10e-04	196	55	5	5318_UP
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A	PDE4DIP SHB MACF1 WWTR1 DNAJB2	1.10e-04	196	55	5	5462_DN
Drug	Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A	SHANK1 TCF3 ZFP36L1 PER1 RAD54L2	1.10e-04	196	55	5	2876_UP
Drug	2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A	TCF3 ZFP36L1 MTSS1 WWTR1 ZNF318	1.10e-04	196	55	5	6934_UP
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HG-U133A	TCF3 ZFP36L1 SRGAP3 PHLPP1 C2CD2L	1.13e-04	197	55	5	1887_UP
Drug	Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	ERN1 ZFP36L1 PER1 RAD54L2 VDR	1.13e-04	197	55	5	2786_UP
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	ZFP36L1 RBBP6 SHB WWTR1 VDR	1.13e-04	197	55	5	6937_DN
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	USP36 PER1 MACF1 ZNF318 PNISR	1.13e-04	197	55	5	7321_DN
Drug	Ergocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A	USP36 ELOA TCF3 WWTR1 ZNF318	1.16e-04	198	55	5	3434_DN
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	PDE4DIP SHB PHLPP1 DNAJB2 C2CD2L	1.16e-04	198	55	5	7034_DN
Drug	Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A	TCF3 PDE4DIP DNAJB2 VDR C2CD2L	1.16e-04	198	55	5	2623_UP
Drug	Articaine hydrochloride [23964-57-0]; Down 200; 12.4uM; PC3; HT_HG-U133A	PDE4DIP RAD54L2 PNISR FAF1 C2CD2L	1.16e-04	198	55	5	7272_DN
Drug	Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A	PDE4DIP AKAP10 WWTR1 ZNF318 VDR	1.16e-04	198	55	5	6226_UP
Drug	Trimethadione [127-48-0]; Down 200; 28uM; MCF7; HT_HG-U133A	CEP350 TCF3 PER1 RAD54L2 FOSL1	1.16e-04	198	55	5	2846_DN
Drug	Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; PC3; HG-U133A	TCF3 MACF1 WWTR1 PNISR C2CD2L	1.16e-04	198	55	5	1940_DN
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	TCF3 MTSS1 WWTR1 PNISR VDR	1.16e-04	198	55	5	7519_DN
Drug	dopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A	SHB ACIN1 DNAJB2 VDR C2CD2L	1.18e-04	199	55	5	491_DN
Drug	Podophyllotoxin [518-28-5]; Down 200; 9.6uM; PC3; HT_HG-U133A	CEP350 TCF3 SHB FAF1 NPAS2	1.18e-04	199	55	5	5841_DN
Drug	Isoconazole [27523-40-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TCF3 PDE4DIP MTSS1 DNAJB2 C2CD2L	1.18e-04	199	55	5	7211_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	USP36 ZNF318 DNAJB2 VDR C2CD2L	1.18e-04	199	55	5	7439_UP
Drug	Amidopyrine [58-15-1]; Down 200; 17.2uM; HL60; HG-U133A	TCF3 ABI2 AKAP10 PNISR FAF1	1.21e-04	200	55	5	1376_DN
Drug	Aroclor 1254	RAF1 ZFP36L1 PTPRN RBBP6 NPAS2	1.63e-04	213	55	5	CID000040470
Drug	2,5-dimethoxy-4-iodoamphetamine	PTPRN PER1 FOSL1 NPAS2	1.85e-04	117	55	4	CID000001229
Disease	cardiovascular disease	USP36 PLEKHG1 ATXN2 DOCK7 ZC3HC1 GRID1 FGD5 ZNF318 VDR	1.88e-07	457	56	9	EFO_0000319
Disease	asthma	USP36 RAF1 ZFP36L1 ATXN2 SRGAP3 MUC16 GRID1 CARD11 FOSL1	1.11e-05	751	56	9	MONDO_0004979
Disease	HbA1c measurement	USP36 RAF1 ATXN2 GRB14 MACF1 FAF1 VDR C2CD2L	3.88e-05	675	56	8	EFO_0004541
Disease	mean arterial pressure	USP36 PLEKHG1 ZFP36L1 ATXN2 STXBP5 FGD5 ZNF318	4.30e-05	499	56	7	EFO_0006340
Disease	Calcium channel blocker use measurement	PLEKHG1 ATXN2 ZC3HC1 ZNF318 VDR	5.30e-05	213	56	5	EFO_0009930
Disease	Pilomyxoid astrocytoma	RAF1 SRGAP3	7.38e-05	7	56	2	C1519086
Disease	fibrinogen measurement, tissue plasminogen activator measurement	ZFP36L1 ATXN2 STXBP5	8.68e-05	45	56	3	EFO_0004623, EFO_0004791
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	9.83e-05	8	56	2	DOID:0060308 (implicated_via_orthology)
Disease	Antihypertensive use measurement	PLEKHG1 ATXN2 FGD5 ZNF318 VDR	1.48e-04	265	56	5	EFO_0009927
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	ZFP36L1 ATXN2 STXBP5	1.67e-04	56	56	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 CNTNAP3B KMT5B CNTNAP3	2.02e-04	152	56	4	DOID:0060041 (implicated_via_orthology)
Disease	smoking status measurement, systolic blood pressure	PLEKHG1 ATXN2 ZNF318 HSD17B4	2.23e-04	156	56	4	EFO_0006335, EFO_0006527
Disease	cortical thickness	PLEKHG1 ATXN2 SRGAP3 DOCK7 ZC3HC1 MACF1 AKAP10 ZNF318 FAF1	2.30e-04	1113	56	9	EFO_0004840
Disease	tissue plasminogen activator measurement, coronary artery disease	ATXN2 STXBP5 ZC3HC1	3.38e-04	71	56	3	EFO_0001645, EFO_0004791
Disease	Ischemic stroke, tissue plasminogen activator measurement	ATXN2 STXBP5	3.66e-04	15	56	2	EFO_0004791, HP_0002140
Disease	autism spectrum disorder (is_implicated_in)	MBD5 VDR	4.17e-04	16	56	2	DOID:0060041 (is_implicated_in)
Disease	factor VIII measurement, Ischemic stroke	ATXN2 STXBP5	5.93e-04	19	56	2	EFO_0004630, HP_0002140
Disease	Inhalant adrenergic use measurement	ZFP36L1 MUC16 CARD11	8.16e-04	96	56	3	EFO_0009941
Disease	white matter microstructure measurement	PLEKHG1 ATXN2 ABI2 SRGAP3 CARD11	8.64e-04	390	56	5	EFO_0005674
Disease	Ovarian Serous Adenocarcinoma	RAF1 ERN1	8.72e-04	23	56	2	C1335177
Disease	Malignant neoplasm of breast	RAF1 SRGAP3 PER1 DNAJC21 MACF1 FGD5 ZNF318 VDR	9.04e-04	1074	56	8	C0006142
Disease	pulse pressure measurement	USP36 PLEKHG1 ABI2 SHB FGD5 ZNF318 MBD5 FAF1 NPAS2	1.15e-03	1392	56	9	EFO_0005763
Disease	von Willebrand factor measurement, coronary artery disease	ATXN2 STXBP5 ZC3HC1	1.48e-03	118	56	3	EFO_0001645, EFO_0004629
Disease	diastolic blood pressure, unipolar depression	PLEKHG1 ATXN2	1.49e-03	30	56	2	EFO_0003761, EFO_0006336
Disease	Ischemic stroke, von Willebrand factor measurement	ATXN2 STXBP5	1.49e-03	30	56	2	EFO_0004629, HP_0002140
Disease	lymphocyte percentage of leukocytes	ERN1 ATXN2 STXBP5 CARD11 FAF1 VDR	1.60e-03	665	56	6	EFO_0007993
Disease	blood urea nitrogen measurement	ATXN2 ZNF318 MBD5 RSBN1L FAF1	1.66e-03	452	56	5	EFO_0004741
Disease	cancer (implicated_via_orthology)	RAF1 RBBP6 MACF1 WWTR1	1.69e-03	268	56	4	DOID:162 (implicated_via_orthology)
Disease	loneliness measurement	SHB MACF1 MBD5	1.71e-03	124	56	3	EFO_0007865
Disease	eosinophil count	ZFP36L1 ATXN2 ZC3HC1 CARD11 PEAK1 MBD5 RSBN1L FOSL1 VDR	1.83e-03	1488	56	9	EFO_0004842
Disease	esterified cholesterol measurement	ATXN2 DOCK7 ANKRD17	1.87e-03	128	56	3	EFO_0008589
Disease	systolic blood pressure, alcohol drinking	PLEKHG1 ATXN2 ZNF318	1.87e-03	128	56	3	EFO_0004329, EFO_0006335

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSRHTPSFSGDSSSS	VDR	171	P11473
SRSRSPDSSGSRSHS	ACIN1	591	Q9UKV3
RSSFSSSSELSSSHG	CNTNAP3	41	Q9BZ76
SHPGSSDSSASQSSV	AKAP10	536	O43572
PSCESTSNGRHSASS	RAD54L2	1141	Q9Y4B4
RPPNSSSSSGSSSAH	ANKRD17	2091	O75179
SSGGSHPSSRSSSRE	ABI2	246	Q9NYB9
HAFTFNTSSPSSEGS	RAF1	236	P04049
GLNTSHSPSASSRSS	NPAS2	401	Q99743
SASPTHENSVSSGSS	MUC16	2011	Q8WXI7
FSDAAQASPSSHSST	PTPRN	661	Q16849
SRSTSHTSDFNPNSG	ATXN2	526	Q99700
PSRSSRHFSKSDSFS	KMT5B	106	Q4FZB7
ESRGASQRSSHSSSS	PER1	61	O15534
NSSDSRSSGSHSHSP	MTSS1	281	O43312
GQSSPQRSYSSSHSS	PEAK1	716	Q9H792
SSSRSSSESSYHGPS	FGD5	676	Q6ZNL6
HSPFSSFASQASGSS	KDM3B	646	Q7LBC6
HARAPSSSSLNSATS	DNAJC21	506	Q5F1R6
FHSSRTSLAGDTSNS	MACF1	7276	Q9UPN3
PSGSQTRSHSSSASS	RBBP6	1706	Q7Z6E9
STSGRQHTTFSAESS	DOCK7	1311	Q96N67
SGPSNTSHSSSRDSH	C2CD2L	486	O14523
SSHASASSISFNPSP	ELOA	731	Q14241
SGTSSPSTSPRASNH	ERN1	521	O75460
SSSFPGHSDFSSSSF	DNAJB2	141	P25686
NHTSRATSTATSGFA	HSD17B4	311	P51659
HSSGAQSAASSRSST	CEP350	1156	Q5VT06
SDSTPNSDTGHSFCS	AKNAD1	641	Q5T1N1
SNSSPNSAASFSGHA	CCDC85A	496	Q96PX6
SPQRSRSSSTSSDHG	MBD5	456	Q9P267
SHGTSRTLSSGPSSN	GRID1	936	Q9ULK0
THGSPTASSQSSATN	GRB14	416	Q14449
HSSTTGTPSSDGRQS	ENAM	1066	Q9NRM1
HPASAPTSSSSSAFR	FAF1	71	Q9UNN5
ASSSASSSLHARQSP	GOLGA8B	56	A8MQT2
FGPSSIHSSSSSHQS	CARD11	611	Q9BXL7
RSSFSSSSELSSSHG	CNTNAP3B	41	Q96NU0
SAHRKSSSSSGDPSS	FOSL1	246	P15407
SPSSSRSSFSFSAGT	RSBN1L	96	Q6PCB5
SSSSSSGSPHLYRSS	SHB	151	Q15464
SHPSTSSSSSDGLRD	STXBP5	581	Q5T5C0
PSASSSSTSTRHLQG	SHANK1	1971	Q9Y566
HSSRASATESVSFSG	STK31	6	Q9BXU1
SDTSSRSFFDPTSQH	ZC3HC1	411	Q86WB0
SSHSGSDSPTLDNSR	ZFP36L1	311	Q07352
RPSDDNSTFSSTQSH	UBTFL1	26	P0CB47
HRSSSSSSSGVGSPA	SRGAP3	1066	O43295
SPDHSSNNFSSSPST	TCF3	341	P15923
SSSSAAAASHSPGAA	PHLPP1	141	O60346
HSGSDSSGRSSSESP	PNISR	751	Q8TF01
SFGSTSSSASSRDSH	PLEKHG1	11	Q9ULL1
SSSTSSSQDHPLYSG	ZNF318	401	Q5VUA4
DRRGSSSSSPEHSAS	USP36	606	Q9P275
PDSGSHSRQSSTDSS	WWTR1	56	Q9GZV5
SDSHRSPSSTSFLSD	PDE4DIP	1601	Q5VU43