Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

IQSEC3 MYCBP2 MCF2L2 ARHGEF38 RAPGEF1 DENND2B ARFGEF3 RAB3IP DNMBP SH3BP5

1.69e-0623112310GO:0005085
GeneOntologyMolecularFunctionenzyme regulator activity

RGPD4 IQSEC3 TANK MYCBP2 GAS6 MCF2L2 ARHGEF38 RAPGEF1 DENND2B RGS12 ARFGEF3 THBS1 SERPINB9 RAB3IP MAP3K13 BSN POLG2 DNMBP SH3BP5 SORL1 SPINK5 WDTC1

5.04e-05141812322GO:0030234
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 IQSEC3 MYCBP2 MCF2L2 ARHGEF38 RAPGEF1 DENND2B RGS12 ARFGEF3 RAB3IP DNMBP SH3BP5

7.06e-0550712312GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 IQSEC3 MYCBP2 MCF2L2 ARHGEF38 RAPGEF1 DENND2B RGS12 ARFGEF3 RAB3IP DNMBP SH3BP5

7.06e-0550712312GO:0030695
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

MSR1 THBS1 SORL1

1.74e-04181233GO:0030169
DomainINT_SG_DDX_CT_C

CT45A1 CT45A7 CT45A3

1.45e-0581213PF15300
DomainINT_SG_DDX_CT_C

CT45A1 CT45A7 CT45A3

1.45e-0581213IPR029307
DomainTSP_1

THSD7A UNC5B THSD1 THBS1 ADAMTS9

5.47e-05631215PF00090
DomainTSP1

THSD7A UNC5B THSD1 THBS1 ADAMTS9

6.36e-05651215SM00209
DomainTSP1_rpt

THSD7A UNC5B THSD1 THBS1 ADAMTS9

6.36e-05651215IPR000884
DomainTSP1

THSD7A UNC5B THSD1 THBS1 ADAMTS9

6.36e-05651215PS50092
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THSD7A THSD1 THBS1 ADAMTS9 MUC20

6.12e-0568875M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THSD7A THSD1 THBS1 ADAMTS9

9.44e-0539874M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THSD7A THSD1 THBS1 ADAMTS9

9.44e-0539874MM15165
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

USP53 TET2 HIVEP1 TTC28 MYCBP2 TEX2 MATR3 BACH1 DENND2B RGS12 STIM1 ARFGEF3 MTMR4 PTPN13 ALMS1 PHF3 PLCH1 DNMBP WDR62

4.33e-108611281936931259
Pubmed

Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

CT45A6 CT45A1 CT45A7 CT45A3 CT45A5

1.82e-0915128515905330
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RIOK1 WAPL TANK TTC28 MYCBP2 TEX2 VPS4B SRPRA ICE1 PAPOLG JPH1 MTMR4 ALMS1 CEBPZ PHF3 PLCH1 WDR62

1.86e-097331281734672954
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

FAM193B MATR3 RNF115 AKAP8L PTPN13 LPIN2 PLCH1 DYNC1H1 WDR62 WDTC1

1.64e-082321281025515538
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP104 USP53 TET2 WAPL RRP1B TEX2 MATR3 ICE1 FEM1C KIAA1614 SENP6 BSN DNMBP

8.69e-085291281314621295
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

THSD7A THBS1 FBN1 PBXIP1 CDCA7L SPINK5

2.60e-0771128633541421
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 TET2 HIVEP1 TTC28 MYCBP2 VPS4B ICE1 AKAP8L PTPN13 ALMS1 WDR62

4.58e-074181281134709266
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EAPP RRP1B MYCBP2 TEX2 UNC5B BACH1 OBSL1 SRPRA CCDC77 DNTTIP2 JPH1 STIM1 PTPN13 CEBPZ HTATSF1 PLCH1 SUCO EIF2AK3 PBXIP1 WDR62

5.36e-0714871282033957083
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TET2 THSD7A TTC28 MCF2L2 ALMS1 PDZD2 WDTC1

5.63e-07130128712421765
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TET2 WAPL TTC28 MYCBP2 BACH1 MCF2L2 OBSL1 CMYA5 AKAP8L JPH1 THBS1 PTPN13 FBN1 ADAMTS9 SENP6 PBXIP1 DYNC1H1 SH3BP5

1.19e-0612851281835914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IQSEC3 TTC28 OBSL1 ADGRL1 CSMD3 ARFGEF3 KANSL1 PHF3 DYNC1H1 PDZD2

2.87e-064071281012693553
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

WAPL RRP1B MYCBP2 AKAP8L DNTTIP2 CEBPZ PHF3 NKTR UTP3 EIF2AK3

5.70e-064401281034244565
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

WAPL HIVEP1 MYCBP2 MATR3 BACH1 REXO1 AKAP8L PAPOLG KANSL1 PHF3 SENP6 DNMBP WDR62

6.01e-067741281315302935
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

HIVEP1 RRP1B MYCBP2 MATR3 ICE1 ARFGEF3 PHF3 HTATSF1 MTBP

8.16e-06361128926167880
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

FAM193B TTC28 TEX2 ARFGEF3 PTPN13 ALMS1 WDR62

1.31e-05209128736779422
Pubmed

Tolerance Biomarkers in Liver Transplantation: Independent External Validation of the Predictive Strength of SENP6 and FEM1C Gene Expression.

FEM1C SENP6

1.34e-052128230720688
Pubmed

Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association.

TRPA1 STIM1

1.34e-052128223994313
Pubmed

Disruption of the murine lecithin:cholesterol acyltransferase gene causes impairment of adrenal lipid delivery and up-regulation of scavenger receptor class B type I.

LCAT MSR1

1.34e-05212829188474
Pubmed

PERK/ATF4-dependent expression of the stress response protein REDD1 promotes proinflammatory cytokine expression in the heart of obese mice.

DDIT4 EIF2AK3

4.02e-053128236383638
Pubmed

Expression and Localization of Thrombospondins, Plastin 3, and STIM1 in Different Cartilage Compartments of the Osteoarthritic Varus Knee.

STIM1 THBS1

4.02e-053128233802838
Pubmed

Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation.

MSR1 ADGRE1

4.02e-053128212101265
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CEP104 IQSEC3 MYCBP2 TEX2 ADGRL1 RAB3IP PRICKLE2 BSN

4.58e-05347128817114649
Pubmed

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.

ARX DYNC1H1 WDR62

5.30e-0520128336551904
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RIOK1 TTC28 UNC5B SRPRA THSD1 JPH1 STIM1 PTPN13 PLCH1 EIF2AK3 DYNC1H1

6.50e-057081281139231216
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

HIVEP1 TTC28 OBSL1 PAPOLG ARFGEF3 ALMS1 SENP6 BSN DNMBP SORL1

6.73e-055881281038580884
Pubmed

Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly.

THSD1 THBS1

8.02e-054128215371459
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

MATR3 KANSL1 ALMS1 DYNC1H1 SH3BP5

8.48e-05120128531413325
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FAM193B THSD7A REXO1 RSPRY1 USP20 NPHP3 ALMS1 ADAMTS9 PLCH1

9.23e-05493128915368895
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

TANK MYCBP2 SRPRA AKAP8L STIM1 ABCB11 NKTR

9.36e-05285128732838362
Pubmed

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

USP53 TET2 ARHGEF38 LRIT3

9.37e-0564128420332099
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

RIOK1 NWD1 WAPL BACH1 SRPRA AKAP8L RGS12 IFIH1 UTP3

9.81e-05497128936774506
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RIOK1 RRP1B MYCBP2 BACH1 OBSL1 RSPRY1 STIM1 PTPN13 NPHP3 RAB3IP NKTR DYNC1H1 WDR62 SORL1 WDTC1

1.09e-0413211281527173435
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RIOK1 TTC28 RRP1B MATR3 CSMD3 AKAP8L JPH1 THBS1 EIF2AK3

1.25e-04513128925798074
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TTC28 RRP1B MYCBP2 TEX2 MATR3 OBSL1 SRPRA CCDC77 JPH1 STIM1 ARFGEF3 ALMS1 UTP3 SUCO EIF2AK3 WDR62

1.26e-0414961281632877691
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

RRP1B CEBPZ HTATSF1 UTP3 CDCA7L WDR62

1.33e-04210128616565220
Pubmed

NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.

UCKL1 BTG4

1.33e-045128216709802
Pubmed

Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.

TET2 ADGRE1

1.33e-045128229108636
Pubmed

Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204).

MSR1 ADGRE1

1.33e-045128215580571
Pubmed

Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2α phosphorylation, ATF4-dependent cascade.

DDIT4 EIF2AK3

1.33e-045128223000413
Pubmed

Mohawk is a novel homeobox gene expressed in the developing mouse embryo.

TCF15 MKX

1.33e-045128216408284
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CT45A1 TANK RRP1B AFF3 GAS6 INTS1 OBSL1 DNTTIP2 STIM1 CT45A3 NKTR MAP3K13

1.42e-049101281236736316
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RIOK1 WAPL TTC28 OBSL1 SRPRA AKAP8L RSPRY1 PLCH1 PBXIP1 SORL1

1.53e-046501281038777146
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

THSD7A TTC28 MYCBP2 OBSL1 ALMS1 PHF3

1.93e-04225128612168954
Pubmed

The tight-skin (Tsk) mutation is closely linked to B2m on mouse chromosome 2.

THBS1 FBN1

2.00e-04612828111131
Pubmed

SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.

TANK IFIH1

2.00e-046128234084167
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

TET2 CT45A6 CT45A1 TRPA1 ZNF235 MEIS2 CT45A7 SERPINB9 FBN1 CT45A3

2.04e-046741281037196079
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

WAPL TTC28 MYCBP2 MATR3 PTPN13 ALMS1 CEBPZ PHF3 DYNC1H1

2.06e-04549128938280479
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CEP104 CCDC77 CNTROB ALMS1 DYNC1H1

2.13e-04146128521399614
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 IQSEC3 MATR3 JPH1 PRICKLE2 BSN

2.22e-04231128616452087
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

RRP1B MATR3 DNTTIP2 CEBPZ UTP3

2.27e-04148128532538781
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B MYCBP2 INTS1 RAPGEF1 ADGRL1 ICE1 CNTROB REXO1 KANSL1 DOK4 UCKL1 DNMBP DYNC1H1

2.28e-0411051281335748872
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TTC28 SRPRA CCDC77 CNTROB AKAP8L PTPN13 ALMS1 WDR62

2.57e-04446128824255178
Pubmed

MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.

TANK PBXIP1

2.79e-047128224488098
Pubmed

Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy.

THBS1 EIF2AK3

2.79e-047128234168130
Pubmed

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.

MYCBP2 RGS12

2.79e-047128236700049
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 WAPL EAPP MATR3 BACH1 AKAP8L JPH1 THBS1 KANSL1 HTATSF1 DYNC1H1 WDR62 WDTC1

3.48e-0411551281320360068
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

TEX2 UNC5B SRPRA USP20 JPH1 STIM1 EIF2AK3 PBXIP1

3.54e-04468128831056421
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

TTC28 INTS1 OBSL1 CNTROB ALMS1 CEBPZ HTATSF1 CDCA7L

3.59e-04469128827634302
Pubmed

Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity.

TCF15 HOXB6

3.71e-048128226718008
Pubmed

Retinal transcriptome of neonatal mice after optic nerve injury.

THBS1 FBN1

3.71e-048128237252932
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TTC28 MATR3 CCDC77 PTPN13 ALMS1 DNMBP

4.44e-04263128634702444
Pubmed

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.

MCF2L2 CMYA5 DYNC1H1

4.69e-0441128319343720
Pubmed

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.

MEIS2 ADGRE1

4.76e-049128230758286
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

HIVEP1 MYCBP2 CMYA5 DNTTIP2 JPH1 NPHP3 ALMS1 ADAMTS9

5.27e-04497128823414517
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

MYCBP2 CNTROB ALMS1 NKTR

5.42e-04101128424613305
Pubmed

A census of human transcription factors: function, expression and evolution.

HIVEP1 TCF15 LHX4 BACH1 ARX MEIS2 HOXB6 CEBPZ SP6 MKX PLEK

5.50e-049081281119274049
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

THSD7A ICE1 USP20 DNMBP

5.63e-04102128410231032
Pubmed

Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.

MSR1 ADGRE1

5.93e-0410128210381505
Pubmed

Identification of a new family of Pbx-related homeobox genes.

MEIS2 THBS1

5.93e-041012828950991
Pubmed

Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection.

MSR1 ADGRE1

5.93e-0410128220488784
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

IQSEC3 TTC28 PLCH1 WDTC1

6.06e-04104128410470851
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

WAPL RRP1B MATR3 DNTTIP2 PHF3 UTP3

6.51e-04283128630585729
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FAM193B RIOK1 WAPL MATR3 ICE1 DNTTIP2 PTPN13 ALMS1 SENP6 HTATSF1 WDR62

6.94e-049341281133916271
Pubmed

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.

UNC5B ADGRE1

7.23e-0411128228576770
Pubmed

Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.

HIVEP1 SH3BP5

7.23e-0411128222488850
Pubmed

A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.

MSR1 FBN1

7.23e-0411128217903305
Pubmed

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner.

THBS1 EIF2AK3

7.23e-0411128238678560
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

TEX2 SRPRA JPH1 STIM1 EIF2AK3

7.27e-04191128531177093
Pubmed

DNA sequence and analysis of human chromosome 8.

INTS1 ZNF705G JPH1

7.46e-0448128316421571
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

WAPL HIVEP1 RRP1B MATR3 ICE1 DNTTIP2 CEBPZ PHF3 SENP6 HTATSF1 UTP3

8.25e-049541281136373674
Pubmed

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.

MYCBP2 DYNC1H1

8.66e-0412128229293652
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

WAPL TTC28 GAS6 OBSL1 AKAP8L DNTTIP2 JPH1 ALMS1 UCKL1 WDR62 SORL1 WDTC1

8.78e-0411161281231753913
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

UNC5B ADGRL1 AKAP8L JPH1 STIM1 PTPN13 PLCH1

9.76e-04421128736976175
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

MALRD1 ABCB11

1.02e-0313128211682476
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

TET2 PRICKLE2

1.02e-0313128226989192
Pubmed

The Mohawk homeobox gene is a critical regulator of tendon differentiation.

FBN1 MKX

1.02e-0313128220498044
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RGPD4 IQSEC3 MYCBP2 TEX2 BACH1 ADGRL1 SRPRA AKAP8L STIM1 ARFGEF3 PRICKLE2 BSN

1.05e-0311391281236417873
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

PAPOLG PHF3 SENP6 BSN SORL1

1.06e-03208128533230847
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

WAPL RRP1B MATR3 SRPRA AKAP8L DNTTIP2 PAPOLG CT45A3 CEBPZ PHF3 UTP3

1.10e-039891281136424410
Pubmed

The protein interaction landscape of the human CMGC kinase group.

RRP1B AFF3 BACH1 OBSL1 ICE1 ALMS1 PHF3 WDR62 SORL1

1.12e-03695128923602568
Pubmed

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.

TANK VPS4B DYNC1H1

1.17e-0356128327103069
Pubmed

Pediatric Genetic Cholestatic Liver Disease Overview

USP53 ABCB11

1.19e-0314128236108118
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

WAPL RRP1B MATR3 AKAP8L DNTTIP2 CEBPZ PHF3 UTP3 CDCA7L WDR62

1.19e-038471281035850772
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

USP53 RIOK1 TANK TTC28 CCDC77 RGS12 ALMS1 DNMBP DYNC1H1 WDR62

1.26e-038531281028718761
Pubmed

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity.

FBN1 ADGRE1

1.37e-0315128236207400
Pubmed

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.

DACT2 DOK4 UTP3 PLEK

1.39e-03130128426598620
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

TET2 RIOK1 MATR3 AKAP8L ALMS1

1.42e-03222128535941108
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

AFF3 CCDC77 REXO1 AKAP8L SENP6

1.42e-03222128537071664
Pubmed

A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.

THBS1 FBN1

1.56e-031612827633422
Pubmed

Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration.

THBS1 ADAMTS9

1.56e-0316128231669249
InteractionSFN interactions

USP53 TET2 MYCBP2 TEX2 MATR3 BACH1 COP1 DENND2B RNF115 RGS12 MTMR4 PTPN13 ALMS1 PHF3 RAB3IP PLCH1 DNMBP WDR62

3.09e-0769212618int:SFN
InteractionYWHAH interactions

USP53 TET2 HIVEP1 TTC28 MYCBP2 TEX2 MATR3 DENND2B RNF115 RGS12 STIM1 ARFGEF3 IFIH1 MTMR4 PTPN13 ALMS1 PHF3 MTBP NKTR PLCH1 DNMBP SUCO WDR62

3.10e-07110212623int:YWHAH
InteractionYWHAB interactions

TET2 DDIT4 RIOK1 HIVEP1 TTC28 MYCBP2 MATR3 COP1 DENND2B RNF115 RGS12 STIM1 MTMR4 PTPN13 PHF3 MTBP PLCH1 DNMBP SUCO DYNC1H1 WDR62

1.24e-06101412621int:YWHAB
InteractionYWHAZ interactions

TET2 DDIT4 HIVEP1 TTC28 MYCBP2 TEX2 MATR3 OBSL1 COP1 SRPRA DENND2B RNF115 RGS12 STIM1 MTMR4 PTPN13 PHF3 LPIN2 MTBP PLCH1 DNMBP SUCO DYNC1H1 WDR62

1.92e-06131912624int:YWHAZ
InteractionYWHAG interactions

USP53 TET2 HIVEP1 TTC28 MYCBP2 MATR3 DENND2B RNF115 RGS12 DNTTIP2 STIM1 MTMR4 PTPN13 ALMS1 PHF3 MTBP NKTR PLCH1 DNMBP SUCO DYNC1H1 WDR62

9.11e-06124812622int:YWHAG
InteractionFBXW11 interactions

FAM193B HIVEP1 MATR3 RAPGEF1 RNF115 AKAP8L PTPN13 LPIN2 PLCH1 DYNC1H1 WDR62 WDTC1

4.21e-0547312612int:FBXW11
CytobandXq26.3

CT45A6 CT45A1 CT45A3 CT45A5 HTATSF1

1.31e-06671285Xq26.3
CytobandEnsembl 112 genes in cytogenetic band chrXq26

CT45A6 CT45A1 CT45A7 CT45A3 CT45A5 HTATSF1

9.11e-061711286chrXq26
Cytoband2q24

IFIH1 ABCB11

4.17e-041112822q24
GeneFamilyClassical BAR domain containing

ARHGEF38 DNMBP

4.80e-0487621292
CoexpressionCHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP

THBS1 SERPINB9 KANSL1 MAP3K13 SORL1 MUC20

3.93e-06861276M19610
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_1_CELL

CT45A6 CT45A1 CT45A7 CT45A3 CT45A5

2.16e-05691275M45681
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DDIT4 WAPL TANK MYCBP2 MATR3 RAPGEF1 SRPRA ICE1 USP20 DNTTIP2 PAPOLG STIM1 SERPINB9 KANSL1 PHF3 LPIN2 SENP6 PBXIP1 DYNC1H1 SORL1

3.29e-05149212720M40023
CoexpressionGSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN

TET2 MYCBP2 BACH1 THBS1 PLEK DNMBP SORL1

4.61e-051941277M7306
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_UP

SRPRA IFIH1 MFSD2A DOK4 ADAMTS9 UTP3 SPINK5

5.59e-052001277M9314
CoexpressionGSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP

TET2 TTC28 MYCBP2 IFIH1 FBN1 DCLRE1C SPINK5

5.59e-052001277M9348
CoexpressionGSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP

TTC28 MYCBP2 MTMR4 RAB3IP SENP6 EIF2AK3 DYNC1H1

5.59e-052001277M3675
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TTC28 AFF3 ARHGEF38 DENND2B ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 SPINK5

1.75e-1018812710ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 DENND2B ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

4.47e-091921279efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A AFF3 ARHGEF38 JPH1 ARFGEF3 PTPN13 PRICKLE2 MAP3K13

6.20e-08185127898b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

7.93e-081911278a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

7.93e-081911278e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

8.26e-08192127858c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

8.59e-081931278738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 ADAMTS9 PLCH1 PDZD2

8.94e-08194127897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

9.72e-0718312776847c1252d6bb105524f812658112517fd351eab
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1 PDZD2

1.01e-061841277369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MATR3 ARHGEF38 ATP10B ARFGEF3 MFSD2A PTPN13 PLCH1

1.08e-061861277acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF3 THSD1 DENND2B MEIS2 SERPINB9 PRICKLE2 SH3BP5

1.12e-061871277ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

TET2 AFF3 RAPGEF1 PAPOLG SERPINB9 DNMBP SH3BP5

1.29e-0619112772af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1

1.29e-061911277276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A TTC28 UNC5B RAPGEF1 MEIS2 ADAMTS9 SH3BP5

1.34e-06192127727ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

1.34e-061921277499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1

1.34e-061921277cc9911e182a289779a2612bc213daae5607689e7
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

TET2 RAPGEF1 PAPOLG MSR1 THBS1 DNMBP SH3BP5

1.44e-0619412777d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 BACH1 DNTTIP2 THBS1 SERPINB9 PLEK EIF2AK3

1.54e-06196127701cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 HIVEP1 BACH1 DNTTIP2 THBS1 SERPINB9 PLEK

1.54e-061961277c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 HIVEP1 BACH1 DNTTIP2 THBS1 SERPINB9 PLEK

1.54e-06196127764c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1

1.64e-061981277f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 MAP3K13 PLCH1

1.64e-0619812772e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 ARHGEF38 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

1.70e-061991277725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 ARHGEF38 MFSD2A PTPN13 MAP3K13 PLCH1 PDZD2

1.70e-0619912778587bd98de7767a575088afbea07a1feb4516b9b
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TET2 DDIT4 MYCBP2 CMYA5 PTPN13 NKTR SORL1

1.70e-0619912773d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TET2 MYCBP2 ATP10B CMYA5 PTPN13 NKTR SORL1

1.70e-061991277262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 MYCBP2 IFIH1 KANSL1 PHF3 NKTR DYNC1H1

1.76e-06200127712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TCF15 RAPGEF1 CSMD3 THBS1 UTP3 WDR62 SPINK5

1.76e-062001277fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellInt-URO-Myeloid-tDC|Int-URO / Disease, Lineage and Cell Type

DDIT4 MATR3 GAS6 OBSL1 CNTROB CDCA7L

7.96e-0616512769803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

WAPL MATR3 COP1 SRPRA RETREG3 ADGRE1

1.11e-05175127635ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A AFF3 ARHGEF38 ARFGEF3 PTPN13 PRICKLE2

1.23e-051781276f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 OBSL1 ARFGEF3 MFSD2A PTPN13 PLCH1

1.27e-051791276fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A TTC28 RAPGEF1 MEIS2 FBN1 ADAMTS9

1.27e-0517912761ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1

1.31e-051801276198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

WAPL MATR3 COP1 SRPRA RETREG3 ADGRE1

1.35e-0518112760d07a67e8ee3bca687b378afbc4044434e63556d
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

WAPL MATR3 SRPRA ICE1 RETREG3 PLEK

1.43e-05183127622bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 OBSL1 ARFGEF3 MFSD2A PTPN13 PLCH1

1.43e-051831276e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 PTPN13 MALRD1 PRICKLE2 MAP3K13

1.53e-051851276673f0c688ae6984bc8027df2da335787924f4137
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

UNC5B DENND2B JPH1 HOXB6 THBS1 FBN1

1.53e-051851276427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ARHGEF38 ARFGEF3 PTPN13 MAP3K13 PLCH1 PDZD2

1.67e-051881276c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ARHGEF38 ARFGEF3 PTPN13 MAP3K13 PLCH1 PDZD2

1.67e-051881276707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1

1.72e-051891276dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF3 THSD1 MEIS2 SERPINB9 PRICKLE2 SH3BP5

1.72e-0518912765d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1

1.77e-05190127627a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

HIVEP1 AFF3 BACH1 RAPGEF1 DNMBP EIF2AK3

1.77e-0519012761e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF15 UNC5B HOXB6 THBS1 DNMBP PDZD2

1.83e-051911276471205494b91be69926dc8159376132bcea0d9b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 AFF3 MEIS2 FBN1 MKX ABCB11

1.83e-0519112762c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.83e-0519112762b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.83e-05191127602e1ae144da7274171e055356d10e8d175c5347f
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.83e-05191127605867b96199a46a415848409130697c810d18937
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.83e-0519112764c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

TET2 AFF3 RAPGEF1 PAPOLG SERPINB9 DNMBP

1.83e-0519112764e4887175200a57e1b041f2f131e3df774df3509
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.83e-051911276de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

USP53 TET2 AFF3 PAPOLG SERPINB9 DNMBP

1.88e-051921276984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.88e-05192127634505a13b8a47c9286c560122fa7861b9c331a08
ToppCellCOVID-19-Myeloid-TRAM1|COVID-19 / Condition, Lineage and Cell class

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.88e-05192127652b8578699325b0d35a2d3ba36772096130ccc0c
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.88e-05192127657c1410ebf90c230993e065eb78385daa3360960
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF15 THSD7A UNC5B THSD1 ADAMTS9 SH3BP5

1.88e-0519212761f35efb0765e05f7f9c881849953bef3965be25a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

AFF3 ARHGEF38 MFSD2A PTPN13 MAP3K13 PLCH1

1.88e-05192127606013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1

1.94e-051931276fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellCOVID-19-Myeloid-TRAM1|Myeloid / Condition, Lineage and Cell class

IQSEC3 UNC5B MSR1 HOXB6 THBS1 MALRD1

1.94e-0519312766e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PLCH1

1.94e-051931276f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 AFF3 THSD1 MEIS2 PRICKLE2 SH3BP5

1.99e-05194127671ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PDZD2

1.99e-05194127653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

AFF3 DENND2B ARFGEF3 PTPN13 PRICKLE2 PLCH1

2.05e-051951276618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A ARHGEF38 ARFGEF3 PTPN13 PRICKLE2 RNF39

2.05e-051951276dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

AFF3 DENND2B ARFGEF3 PTPN13 PRICKLE2 PLCH1

2.05e-05195127606ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

BACH1 MCF2L2 RAPGEF1 MSR1 THBS1 SH3BP5

2.05e-05195127646ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL MYCBP2 CMYA5 JPH1 THBS1 NKTR

2.05e-0519512765c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellASK452|World / Donor, Lineage and Cell class of Lung cells from Dropseq

DDIT4 DNTTIP2 THBS1 SERPINB9 ADAMTS9 PLEK

2.05e-0519512767efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AFF3 ARHGEF38 ARFGEF3 MFSD2A PTPN13 PDZD2

2.11e-0519612767e5addaa844e66f8160e05858c341866a80aed23
ToppCellEndothelial-capillary_endothelial_cell_(Cap1)|World / Lineage, Cell type, age group and donor

TCF15 AFF3 THSD1 MEIS2 PRICKLE2 SH3BP5

2.11e-0519612760ce3ed27d2b9276390952652c17a8d6de13add36
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TTC28 AFF3 PTPN13 KANSL1 PRICKLE2 PDZD2

2.24e-0519812761996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 BACH1 THBS1 SERPINB9 PLEK ADGRE1

2.24e-0519812763a1707318814dabdec48f91fa6bd223f5b879653
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 ARFGEF3 MFSD2A MAP3K13 PLCH1 PDZD2

2.30e-0519912765f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF15 THSD7A UNC5B RAPGEF1 THSD1 ADAMTS9

2.30e-051991276b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 ARFGEF3 PTPN13 MAP3K13 PLCH1 PDZD2

2.30e-0519912765cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TET2 MYCBP2 CMYA5 PTPN13 NKTR SORL1

2.30e-05199127632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

DDIT4 SRPRA MSR1 THBS1 DYNC1H1 SH3BP5

2.37e-052001276e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIVEP1 INTS1 LCAT DENND2B REXO1

4.92e-0513912757e2c10830c3d16109cab3ed0d64b3532481e497d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAD PAPOLG SERPINB9 PLEK CDCA7L

5.45e-051421275c2a3cd9998fd9a8e6b2665347ca5c32511776488
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RGPD4 WAPL MATR3 ICE1 RETREG3

5.63e-051431275bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DACT2 ARHGEF38 LRIT3 PHF3 PDZD2

6.63e-0514812751d9fa6b2ee9feaed39c63d44e638b5c0942d947c
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

WAPL MATR3 COP1 THBS1 ADGRE1

7.52e-0515212752ff0980dfd8d430cca14649151d856edef115720
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WAPL MATR3 ICE1 RETREG3 SORL1

8.25e-0515512750a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B RNF39 MUC20 SPINK5

1.08e-041641275b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B RNF39 MUC20 SPINK5

1.08e-041641275c5b2001280a43da855017361a3f6071a0e492848
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B RNF39 MUC20 SPINK5

1.08e-04164127556e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

UNC5B MATR3 PAPOLG MSR1 PDZD2

1.14e-041661275f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 ARFGEF3 PTPN13 PRICKLE2 MAP3K13

1.14e-041661275c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

MCF2L2 CMYA5 PTPN13 ADGRE1 WDR62

1.17e-0416712751036ac1ef9440612500137af9d1929672b077e4d
ToppCellControl-Epithelial_airway-Club_cells-Airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B PTPN13 MUC20 SPINK5

1.20e-041681275ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCellControl-Epithelial_airway-Club_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B PTPN13 MUC20 SPINK5

1.20e-041681275e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B RNF39 MUC20 SPINK5

1.24e-0416912758c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

TCF15 THSD7A THSD1 MEIS2 SP6

1.24e-041691275605cc2638271803cf1d972ab3fa8f13f89666376
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 ATP10B RNF39 MUC20 SPINK5

1.24e-04169127586041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TCF15 THSD7A THSD1 MEIS2 SP6

1.24e-041691275337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRL1 CNTROB SERPINB9 MTBP CDCA7L

1.24e-041691275822e5b6c1e55e196e6d2a38bf183fd220c45703e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A AFF3 PTPN13 LPIN2 PRICKLE2

1.27e-041701275a2c738e441ced90eeeb1fcc6ca3269b918aaa298
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A

USP53 UNC5B DENND2B RGS12 PAPOLG DOK4 NKTR PBXIP1 WDTC1

1.40e-0619612596062_UP
DrugVigabatrin [60643-86-9]; Down 200; 31uM; MCF7; HT_HG-U133A

TTC28 UNC5B DENND2B RGS12 THBS1 ALMS1 DOK4 PLCH1 WDR62

1.46e-0619712595415_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ARHGEF38 ATP10B IFIH1 DOK4 PHF3 MAP3K13 ADGRE1 SPINK5

1.21e-0519412582223_UP
Drug5707885; Up 200; 50uM; PC3; HT_HG-U133A

DDIT4 THSD7A UNC5B ATP10B ZNF235 MAP3K13 PLCH1 PBXIP1

1.25e-0519512586390_UP
DrugMethiazole; Down 200; 15uM; PC3; HT_HG-U133A

RRP1B DENND2B USP20 IFIH1 THBS1 SENP6 PBXIP1 WDTC1

1.35e-0519712584532_DN
Diseaseapolipoprotein A 1 measurement

TET2 TCF15 THSD7A AFF3 LCAT RNF115 RSPRY1 DOK4 LPIN2 SP6 ABCB11 SORL1

1.55e-0484811812EFO_0004614
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

VPS4B ADGRL1 ADGRE1

1.90e-04281183DOID:1094 (implicated_via_orthology)
Diseaselymphocyte count

TET2 NWD1 HIVEP1 TTC28 GAS6 MSR1 IFIH1 MFSD2A SERPINB9 FBN1 ALMS1 DCLRE1C SP6 PLEK ADGRE1 RNF39

2.43e-04146411816EFO_0004587
DiseaseSevere Congenital Microcephaly

MFSD2A DYNC1H1 WDR62

2.58e-04311183C3853041
DiseaseDisproportionate short stature

SMARCAL1 OBSL1 FBN1 EIF2AK3

2.63e-04771184C0878659
DiseaseMicrolissencephaly

MFSD2A DYNC1H1 WDR62

3.12e-04331183C1956147
Diseasemesangial proliferative glomerulonephritis (biomarker_via_orthology)

RAPGEF1 FBN1

4.37e-0481182DOID:4783 (biomarker_via_orthology)
DiseaseSubarachnoid Hemorrhage

UNC5B THSD1

5.60e-0491182C0038525
Diseasecolorectal cancer, endometrial neoplasm

TET2 RETREG3 MALRD1

6.39e-04421183EFO_0004230, MONDO_0005575
Diseaseage at menarche

TET2 DDIT4 TTC28 AFF3 REXO1 ALMS1 SP6 SENP6 BSN

6.54e-045941189EFO_0004703
Diseasemacula measurement

MEI4 FBN1 KANSL1 ADAMTS9 SORL1

9.97e-041891185EFO_0008375
Diseaseintelligence, self reported educational attainment

TET2 TANK AFF3 BSN

1.27e-031171184EFO_0004337, EFO_0004784
DiseaseMalformations of Cortical Development

DYNC1H1 WDR62

1.40e-03141182C1955869
DiseaseCortical Dysplasia

DYNC1H1 WDR62

1.40e-03141182C0431380
Diseasehousehold income

TET2 TANK THSD7A AFF3 KANSL1 BSN

1.43e-033041186EFO_0009695
Diseasediastolic blood pressure, systolic blood pressure

BACH1 CNTROB DENND2B RGS12 FBN1 MALRD1 ALMS1 WDR62 SH3BP5

1.51e-036701189EFO_0006335, EFO_0006336
Diseaseplatelet crit

TET2 TTC28 AFF3 ITGAD DENND2B KIAA1614 THBS1 SERPINB9 KANSL1 PLEK SORL1

1.54e-0395211811EFO_0007985
DiseaseAutosomal recessive primary microcephaly

MFSD2A WDR62

1.61e-03151182cv:C3711387
Diseaseobesity (implicated_via_orthology)

STIM1 ALMS1 ADAMTS9 LPIN2 WDTC1

1.76e-032151185DOID:9970 (implicated_via_orthology)
Diseasecholine measurement

LCAT KANSL1 ABCB11 PLCH1

1.87e-031301184EFO_0010116
DiseaseMuscle hypotonia

INTS1 KANSL1

2.07e-03171182C0026827
DiseaseCharcot-Marie-Tooth disease type 2

JPH1 DYNC1H1

2.07e-03171182cv:C0270914
DiseaseIntellectual Disability

IQSEC3 AFF3 MEIS2 MFSD2A KANSL1 DYNC1H1 WDR62

2.18e-034471187C3714756
DiseaseProfound Mental Retardation

MFSD2A KANSL1 DYNC1H1 WDR62

2.39e-031391184C0020796
DiseaseMental Retardation, Psychosocial

MFSD2A KANSL1 DYNC1H1 WDR62

2.39e-031391184C0025363
DiseaseMental deficiency

MFSD2A KANSL1 DYNC1H1 WDR62

2.39e-031391184C0917816
DiseaseMicrocephaly

MFSD2A DYNC1H1 WDR62

2.48e-03671183C0025958
Diseasep-tau:beta-amyloid 1-42 ratio measurement

TTC28 UNC5B

2.59e-03191182EFO_0007709
Diseasefasting blood insulin measurement

TET2 UNC5B MAP3K19

2.70e-03691183EFO_0004466
Diseaseseborrheic dermatitis

UNC5B PRICKLE2

2.87e-03201182EFO_1000764
Diseasecognitive function measurement, self reported educational attainment

MYCBP2 AFF3 MTMR4 KANSL1 ALMS1 BSN

3.10e-033551186EFO_0004784, EFO_0008354
DiseaseAlzheimer disease, educational attainment

TET2 AFF3 KANSL1 BSN SORL1

3.21e-032471185EFO_0011015, MONDO_0004975
Diseaseworry measurement

HIVEP1 MYCBP2 RGS12 KANSL1

3.45e-031541184EFO_0009589
DiseaseAutosomal Recessive Primary Microcephaly

MFSD2A WDR62

3.48e-03221182C3711387
DiseaseRenal glomerular disease

SMARCAL1 NPHP3

3.80e-03231182C0268731
DiseaseGlomerulopathy Assessment

SMARCAL1 NPHP3

3.80e-03231182C4521256

Protein segments in the cluster

PeptideGeneStartEntry
EESRSGETNSCVEEI

AFF3

291

P51826
DDSRTASQLDEFQEC

COP1

381

Q8NHY2
TDTEGDSESCSAREQ

BACH1

506

O14867
DFSLGSTVQFSCDED

CSMD3

501

Q7Z407
RTSSSIVFEDSGCDN

EIF2AK3

801

Q9NZJ5
AFEDDSCSNFVSEDD

SH3BP5

301

O60239
SDLDESESCTAEDGA

ADGRL1

1356

O94910
DCNSYLQRSTGEESD

ARHGEF38

446

Q9NXL2
EESECHSEFENTTRS

ALMS1

3461

Q8TCU4
VGECEQSESSAFKAD

CCDC77

181

Q9BR77
SFSGDDLECRETASS

CT45A5

101

P0DMU8
RECLTGESESSSEDE

EAPP

46

Q56P03
DCNSVGELNTRFSDD

ABCB11

191

O95342
RTVDESVSSGNQDDC

DNMBP

206

Q6XZF7
SDSDSDDECNTLNGL

DENND2B

1011

P78524
SFSGDDLECRETASS

CT45A7

101

P0DMV0
ATTDSDERDDASVCS

ATP10B

656

O94823
DERDDASVCSGGDST

ATP10B

661

O94823
ATRTDCSDNSDSDND

AKAP8L

291

Q9ULX6
GEEQDSLDTSSEIRC

NWD1

1246

Q149M9
TEACDGSDDIFGLST

RAB3IP

141

Q96QF0
TEGDTATFECELSQA

OBSL1

1641

O75147
ECGADVNVRDSDDNS

FEM1C

516

Q96JP0
DGERCRDDSFFGETS

MATR3

226

P43243
AEAETRSQDGDTAAC

INTS1

1741

Q8N201
REAIFDTLCTDDSSE

MUC20

136

Q8N307
GSESGKDTCDEFRSQ

SPINK5

766

Q9NQ38
GDVCSSDSFNEDIAV

MEIS2

111

O14770
NESRNDDDDTSVCLG

ERVMER34-1

166

Q9H9K5
SDANSTISFGDVDCD

JPH1

251

Q9HDC5
DNSDNCRTDSEEAGT

KIAA1614

616

Q5VZ46
RSADCSVQTDDEDSA

BSN

2606

Q9UPA5
GCSSREFSSMDTFED

MCF2L2

1006

Q86YR7
RLSVSSDDSCSEDGE

MKX

156

Q8IYA7
TDFQSSDCLAREEVG

PDZD2

316

O15018
SFSGDDLECRETASS

CT45A3

101

Q8NHU0
LRCSEQAFDSDVTDS

KANSL1

391

Q7Z3B3
AEDCGVSDSELSFRE

LHX4

246

Q969G2
SNFSSSDCQDEEGRK

POLG2

271

Q9UHN1
CITFSTERVEGDDSQ

LRIT3

566

Q3SXY7
EESCDSFDSLESGKQ

CDCA7L

41

Q96GN5
EDASAEDSCAEAAAS

IQSEC3

546

Q9UPP2
TEDFGSDHSEDCLSE

MTMR4

1081

Q9NYA4
QEDTDSCSESVKFDA

MSR1

11

P21757
DCSEKQSEDGSEREF

HTATSF1

551

O43719
SDCAQDKSVFGETEE

HOXB6

106

P17509
EDTATFSGDDFSCVA

ITGAD

1141

Q13349
TEENEFSGCRSESSL

MAP3K13

776

O43283
ALRDEASSSGCSETD

MFSD2A

521

Q8NA29
QRNSTSDDDSGCALE

PRICKLE2

21

Q7Z3G6
ICDFTDQCGDSSDER

MALRD1

51

Q5VYJ5
LDSSCLDSSRDTDNG

PAPOLG

526

Q9BWT3
DENGSVADESACATL

ADAMTS9

1211

Q9P2N4
FCGERSESFTEEGLD

CEP104

756

O60308
SFSGDDLECRETASS

CT45A1

101

Q5HYN5
DTEVESEAFSCSEGS

ICE1

1106

Q9Y2F5
FTNFVDCEESNSESE

DCLRE1C

446

Q96SD1
SSDEEGGAQSRDCDL

DACT2

701

Q5SW24
GLGEEEDSSSERSSC

FAM193B

386

Q96PV7
EGFDRSTSLESSDCE

DDIT4

41

Q9NX09
DSGFALDSEERNCTD

FBN1

1056

P35555
FSLDQTGSSCEDVDE

FBN1

2556

P35555
FELSSDGRTCQDIDE

GAS6

186

Q14393
DVSDIGSDNCSLADE

ARFGEF3

626

Q5TH69
LFEDDERSTDSSQQC

ARFGEF3

1841

Q5TH69
SCFSEADEEDIGSTA

CMYA5

1036

Q8N3K9
ELTGSDCSESNAEIE

IFIH1

196

Q9BYX4
DGEDSVCLSAGSDSE

ARX

306

Q96QS3
EFGESDLRSACDTVD

DYNC1H1

4206

Q14204
EDGDDTVATRSTELC

LCAT

366

P04180
SDDSDVDVCFTDDQS

PRDM13

681

Q9H4Q3
AAACAVTDLSDDSDF

UTP3

356

Q9NQZ2
SFSGDDLECRETASS

CT45A6

101

P0DMU7
DDSARTFTCDSELEA

DOK4

86

Q8TEW6
SISRSEEFDQDGDCS

MAP3K19

41

Q56UN5
ELIDTFEDDNCFSSG

CEBPZ

846

Q03701
AGSERREEDSFDSDS

CNTROB

126

Q8N137
LGAVECFEEEDSNSR

MTBP

121

Q96DY7
CFEEEDSNSRESLSL

MTBP

126

Q96DY7
LCTADRDFSSGETAT

PTPN13

306

Q12923
DSGCDLSNEQRTESS

MEI4

101

A8MW99
EERTCSDSEDIGSSE

RIOK1

491

Q9BRS2
SCDARFSDSEDEAAT

REXO1

281

Q8N1G1
NCDLREDALDDSVSS

RGPD4

1251

Q7Z3J3
SERCDGFLDCSDESD

SORL1

1531

Q92673
CESGFIEEVTDDSSF

RNF115

41

Q9Y4L5
GSRVFCVEEEDSESS

RRP1B

381

Q14684
CRDDSGTDDSVDTQQ

RSPRY1

46

Q96DX4
NISCVVSDGSADDFS

THSD7A

1366

Q9UPZ6
RSRSCSESDDDDSSE

NKTR

346

P30414
GESDSDDNCTDVTAA

NPHP3

211

Q7Z494
DSGFFCEENSSDDDV

PLEK

221

P08567
DGSTSSAEREDLCQQ

SMARCAL1

756

Q9NZC9
GLCRDEEDTSFESLS

TANK

216

Q92844
CDDSSEFKSVDEGSN

MYCBP2

2951

O75592
GASSRVTCEDLESDS

SP6

71

Q3SY56
SGANSEESTAAEFCR

STIM1

36

Q13586
DSLETCLSSDGGEQD

REELD1

311

A0A1B0GV85
RASSDVSSGTSCDEE

BTG4

136

Q9NY30
VGFISRNSTCEDVDE

ADGRE1

161

Q14246
LTDGEDNTASSCIDE

CLCA4

411

Q14CN2
DSSQDSRDRGNSCDS

USP53

561

Q70EK8
EHSDAEVSCTDNGTF

RETREG3

286

Q86VR2
SENEEDTLCFVENSG

DNTTIP2

456

Q5QJE6
ENRSESDASDQSFGC

TCF15

26

Q12870
IDSLCGSRSENESEA

VPS4B

236

O75351
ASDDEDSSEGQVQCR

WDTC1

661

Q8N5D0
DSDSDRIGDTCDNNQ

THBS1

846

P07996
SETEDDDSHCSFQDR

TRPA1

1076

O75762
AEGVGRFESCSSDEE

RGS12

96

O14924
EEGRCSSSDDDTDVD

PBXIP1

141

Q96AQ6
EVNEEGTEAAAASSC

SERPINB9

321

P50453
DEQLSSLDRDSGQCS

RAPGEF1

361

Q13905
ENICELSEQRGSFSD

THSD1

466

Q9NS62
FDSSICSGEGDDSLR

WAPL

1011

Q7Z5K2
LEDAGSSDISSDAAC

PHF3

336

Q92576
DDSSDDGFLADDNCS

SENP6

941

Q9GZR1
QDLDCSSSDDEGAAQ

SRPRA

291

P08240
QSETDCDVGEALDAS

SUCO

166

Q9UBS9
FECNDSGEDCTRSST

ZNF705G

116

A8MUZ8
RNCRDFDTDITDSSA

UNC5B

401

Q8IZJ1
DEFLSCDSSSDRGEG

USP20

281

Q9Y2K6
DTDENQGTLTFEEFC

PLCH1

191

Q4KWH8
DSGESEADLECSFAA

WDR62

991

O43379
RACASSETESEAGDI

TTC28

1311

Q96AY4
SETACEDRSNAESLD

UCKL1

31

Q9NWZ5
FCLADSDEESSSAGS

TEX2

941

Q8IWB9
VVSEACDADDADNAS

TET2

291

Q6N021
NECEEAFNDSSSLEL

ZNF235

266

Q14590
VSTDEDVRITDCFSG

HIVEP1

2226

P15822
TTAVSSNRDHEDDGC

nan

171

Q8N7P7
ADAASCRDSSGEDAD

RNF39

291

Q9H2S5
AAEDTCDVGVSSDDD

LPIN2

176

Q92539