Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin binding

MYRIP COBL MARCKSL1 MARCKS PHACTR4

6.75e-04479305GO:0003779
DomainMARCKS_1

MARCKSL1 MARCKS

2.17e-062282PS00826
DomainMARCKS_2

MARCKSL1 MARCKS

2.17e-062282PS00827
DomainMARCKS

MARCKSL1 MARCKS

2.17e-062282IPR002101
DomainMARCKS

MARCKSL1 MARCKS

2.17e-062282PF02063
DomainHelicase_C

DDX46 ERCC6

1.12e-02107282PF00271
DomainHELICc

DDX46 ERCC6

1.12e-02107282SM00490
DomainHelicase_C

DDX46 ERCC6

1.14e-02108282IPR001650
DomainHELICASE_CTER

DDX46 ERCC6

1.16e-02109282PS51194
DomainHELICASE_ATP_BIND_1

DDX46 ERCC6

1.16e-02109282PS51192
DomainDEXDc

DDX46 ERCC6

1.16e-02109282SM00487
DomainHelicase_ATP-bd

DDX46 ERCC6

1.18e-02110282IPR014001
Domain-

DOK6 NUMB RASAL2

2.02e-023912832.30.29.30
Pubmed

A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis.

MARCKSL1 MARCKS

7.19e-07230219924305
Pubmed

MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

MARCKSL1 MARCKS

7.19e-0723027862670
Pubmed

MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates.

MARCKSL1 MARCKS

7.19e-0723021516135
Pubmed

Suppression of the lipopolysaccharide-induced expression of MARCKS-related protein (MRP) affects transmigration in activated RAW264.7 cells.

MARCKSL1 MARCKS

7.19e-07230219246034
Pubmed

The regulation of MacMARCKS expression by integrin beta3.

MARCKSL1 MARCKS

7.19e-07230217292354
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

NUMB DLG2 MARCKSL1 MARCKS RASAL2 PHACTR4

7.43e-0737730638117590
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

SNRPGP15 NUMB SETD1A MARCKSL1 DDX46 CPSF2 ALDH3A2

1.96e-0671130733022573
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PWWP2A NUMB MARCKSL1 DDX46 ERCC6 CPSF2 ALDH3A2 RBM19 MARCKS

3.12e-06149730931527615
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

NUMB COBL MARCKSL1 MARCKS RASAL2 PHACTR4

7.94e-0656930630639242
Pubmed

Characteristics of the F52 protein, a MARCKS homologue.

MARCKSL1 MARCKS

1.08e-0563021618855
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SNRPGP15 NUMB MARCKSL1 DDX46 EBNA1BP2 CPSF2 RBM19 MARCKS

1.54e-05137130836244648
Pubmed

Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency.

MARCKSL1 MARCKS

2.01e-0583028922669
Pubmed

Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.

MARCKSL1 MARCKS

3.22e-05103028406449
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

MARCKSL1 MARCKS

3.22e-05103029184108
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MARCKSL1 EBNA1BP2 RBM19 MARCKS RASAL2 PHACTR4

4.58e-0577730635844135
Pubmed

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

NUMB EBNA1BP2

4.72e-05123027596406
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

NUMB STOX2 ALDH3A2 RASAL2

7.50e-0526330434702444
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NUMB COBL STOX2 PLK2 RASAL2 PHACTR4

8.08e-0586130636931259
Pubmed

KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).

SETD1A ERCC6

9.70e-051730222902626
Pubmed

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry.

NUMB MARCKSL1 PHACTR4

1.05e-0410630338891874
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

NUMB MARCKSL1 PHACTR4

1.80e-0412730330442766
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NUMB MARCKSL1 EBNA1BP2 ALDH3A2 MARCKS RASAL2 PHACTR4

2.20e-04148730733957083
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

NUMB ALDH3A2 MARCKS RASAL2 PHACTR4

3.22e-0470830539231216
Pubmed

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.

NUMB PHACTR4

4.20e-043530237381005
Pubmed

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8.

CDS1 ALDH3A2

4.45e-043630238070861
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

NUMB COBL RASAL2 PHACTR4

4.52e-0442130436976175
Pubmed

Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.

NUMB ALDH3A2

7.27e-044630235022314
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

COBL DDX46 EBNA1BP2 ERCC6 ALDH3A2

7.28e-0484730535850772
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SNRPGP15 SETD1A DDX46 EBNA1BP2 CPSF2 USP42

7.95e-04131830630463901
CytobandEnsembl 112 genes in cytogenetic band chr1p35

MARCKSL1 PHACTR4

3.64e-03137302chr1p35
CytobandEnsembl 112 genes in cytogenetic band chr3p22

MYRIP SCN11A

6.46e-03184302chr3p22
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

DLG2 PHACTR4

1.23e-02181172694
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOK6 RASAL2

1.57e-02206172682
GeneFamilyRNA binding motif containing

SETD1A RBM19

1.67e-02213172725
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOK6 NUMB MAS1 MARCKS

6.83e-06184304857ca1fc4de07b300839b22924211dc624453841
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 NUMB DLG2 STOX2

7.28e-061873049d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP COBL STOX2 DPY19L3

9.49e-062003040eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

DOK6 DLG2 PLK2 MARCKSL1

9.49e-06200304c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP COBL PLK2 DPY19L3

9.49e-0620030485c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP PWWP2A DLG2

9.04e-05130303e5acaa9aaa22b10d11410e2c01647b31354c21ed
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP PWWP2A DLG2

1.08e-04138303d5342383c5e52b92c39d7afe76560501be3ea5cd
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP PWWP2A DLG2

1.08e-04138303e2659949944bdf39b23c7275e380a7a937e2726c
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FUT10 MARCKSL1 ERCC6

1.27e-041463035b2608b56204dda9a773988f42ff00a9fa743a39
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

STOX2 MARCKSL1 MAS1

1.67e-04160303bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CDS1 PLK2 MAS1

1.70e-04161303ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

FUT10 DPY19L3 MARCKS

1.73e-04162303e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

STOX2 MARCKSL1 MAS1

1.80e-0416430367c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD1A DLG2 USP42

1.83e-041653030edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD1A DLG2 USP42

1.83e-04165303fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP NUMB STOX2

2.00e-0417030350c6c571591aa4b218caefe5778c570c809f567e
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

COBL STOX2 RASAL2

2.00e-04170303e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 FUT10 ERCC6

2.00e-04170303d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP NUMB STOX2

2.00e-041703038fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP NUMB STOX2

2.00e-041703033232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOK6 ERFL MAS1

2.00e-04170303059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

DOK6 STOX2 EBNA1BP2

2.21e-0417630336f77d878a53b30465b0dea8333a3865dba75613
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COBL DLG2 STOX2

2.25e-04177303b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MYRIP COBL DLG2

2.36e-04180303806e2f6138b630b9d7c41df75ec208e0a2298ee0
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

COBL STOX2 ALDH3A2

2.48e-04183303942530449e9c6583705eeb8f6f12621daea57252
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|390C / Donor, Lineage, Cell class and subclass (all cells)

SETD1A USP42 PHACTR4

2.48e-04183303228092290dbb08785c4eda224e3ad03e99e10fab
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COBL STOX2 ALDH3A2

2.48e-041833037b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A MARCKSL1 MARCKS

2.48e-041833039ca4954faaba50466c35121d6765895e955178aa
ToppCellEndothelial-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

MYRIP PLK2 MARCKSL1

2.48e-041833032c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYRIP STOX2 RASAL2

2.48e-04183303ff95382cfed592190d0636d2b750328471f82e0d
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUMB MARCKSL1 PHACTR4

2.48e-04183303e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 COBL STOX2

2.60e-04186303f28d72b47624b69a580b4429e2be560a26898591
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYRIP STOX2 PLK2

2.60e-0418630392092f11ecce22c14f244e42c499af0822977e6f
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

SCN11A MARCKSL1 MARCKS

2.60e-041863030987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

SCN11A MARCKSL1 MARCKS

2.60e-0418630300ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 MARCKSL1 RASAL2

2.64e-041873030ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COBL ALDH3A2 RASAL2

2.68e-0418830343a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYRIP PLK2 RASAL2

2.68e-041883030026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 MARCKSL1 PHACTR4

2.72e-041893035d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

SCN11A MARCKSL1 MARCKS

2.77e-0419030315978ddd37b521343f88b62dad1643077fc22b2b
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

MYRIP STOX2 PLK2

2.77e-0419030378e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYRIP PLK2 RASAL2

2.77e-04190303d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 DLG2 STOX2

2.77e-04190303989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DLG2 CDS1 STOX2

2.81e-0419130334cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

COBL DLG2 STOX2

2.81e-04191303e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellStriatum-Macroglia-POLYDENDROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

MARCKSL1 EBNA1BP2 MARCKS

2.81e-041913036bc9c7c86040f3ebce08c350e625e345581d4550
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP SCN11A PLK2

2.85e-04192303c0498baa2556e1597c00df2e75efadeb14bd34ef
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PLK2 MARCKSL1 MARCKS

2.85e-04192303c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

PLK2 MARCKSL1 MARCKS

2.85e-04192303c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PLK2 MARCKSL1 MARCKS

2.85e-041923035d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DLG2 CDS1 STOX2

2.85e-04192303fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP SCN11A PLK2

2.85e-04192303cb906b10cad76e978c5c0b966215368ebef30e51
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

STOX2 MARCKSL1 MARCKS

2.85e-04192303cbe57cda44232b183821ac633b60a2668265e616
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYRIP PLK2 MARCKSL1

2.85e-041923030aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLK2 MARCKSL1 ALDH3A2

2.90e-04193303739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

SCN11A MARCKSL1 MARCKS

2.90e-04193303024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUMB PLK2 PHACTR4

2.90e-04193303aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUMB PLK2 PHACTR4

2.90e-04193303c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUMB MARCKSL1 MARCKS

2.94e-041943033ef9e88e66f2f2ae95dcc834ea605c40c60783fc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 MARCKS RASAL2

2.94e-04194303ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COBL STOX2 PHACTR4

2.94e-041943037002937e8903e037332a215d00fbc7c7843b33f2
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COBL DLG2 STOX2

2.94e-0419430353f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYRIP MARCKS RASAL2

2.94e-04194303fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

COBL DLG2 STOX2

2.99e-04195303618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

COBL DLG2 STOX2

2.99e-0419530306ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COBL DLG2 STOX2

2.99e-041953039406866f99555198a9be311fbd65751b70f35446
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYRIP PLK2 MARCKSL1

3.03e-04196303d5d3028fcbfa251a206d17ec33b3b313968f9d79
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYRIP PLK2 MARCKSL1

3.03e-041963035609b2d93172a488b35d854298a3a4e504e17e28
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

MYRIP STOX2 RASAL2

3.03e-04196303e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell(05)_Secretory|World / shred by cell type by condition

COBL PLK2 MARCKSL1

3.03e-041963038032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DLG2 FUT10 MAS1

3.08e-04197303f7ef62d78336812573148f8bfce401877ec4e29c
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYRIP PLK2 MARCKSL1

3.08e-04197303b18f2c14d6720f6ae8520c0800356f4a57393ad3
ToppCelldistal-Endothelial-Bronchial_Vessel_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYRIP PLK2 MARCKSL1

3.08e-04197303f45a93b5ad80a16b760acbaa6467648ffc05a0d3
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYRIP PLK2 MARCKSL1

3.12e-0419830368ee0baa2f5cf239f2356cc59fee9041a7732bba
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYRIP PLK2 MARCKSL1

3.12e-041983034a70a1ab40fe30b90acd97e4e36067db62acc905
ToppCelldistal-Endothelial-Bronchial_Vessel_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYRIP PLK2 MARCKSL1

3.12e-041983035bdffabf80716dd80c1265c3d126c7a25340251c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal|6_mon / Sample Type, Dataset, Time_group, and Cell type.

DOK6 PLK2 MARCKSL1

3.12e-04198303076c862f2a723f0361749377561cae902068b1a0
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYRIP PLK2 MARCKSL1

3.12e-041983035784e0f9988c917026a692a61b09c7e77e540d13
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYRIP DOK6 RASAL2

3.12e-041983030ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STOX2 PLK2 RASAL2

3.12e-04198303f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCelldistal-3-Endothelial-Bronchial_Vessel_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYRIP PLK2 MARCKSL1

3.12e-0419830300fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

DOK6 MARCKSL1 MARCKS

3.17e-041993035b9d355795dd03a22f0961dfd143425c367a4654
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DLG2 PLK2 MARCKSL1

3.17e-04199303f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Vein|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYRIP PLK2 MARCKSL1

3.17e-04199303cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCelldistal-Endothelial-Vein-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYRIP PLK2 MARCKSL1

3.17e-04199303f9fc0482d7ab11f2165b30cce3564b4ff87d61a6
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DLG2 PLK2 MARCKSL1

3.17e-04199303c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

STOX2 MARCKSL1 MARCKS

3.22e-0420030376e90231aa94afc12e618da8ae314c51644acab4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC|2m / Sample Type, Dataset, Time_group, and Cell type.

PLK2 MARCKSL1 MARCKS

3.22e-042003033c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-0420030389a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related|2m / Sample Type, Dataset, Time_group, and Cell type.

PLK2 MARCKSL1 MARCKS

3.22e-042003038e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYRIP PLK2 MARCKSL1

3.22e-04200303ae6cc5462a8a254682793fb8cc348b9721c729bf
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-042003036f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-042003032d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP COBL DPY19L3

3.22e-04200303c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-04200303b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP PLK2 DPY19L3

3.22e-04200303a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-042003033372c488a39fe812fa94e4f0564594186fea3db5
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

STOX2 MARCKSL1 MARCKS

3.22e-04200303e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP COBL STOX2

3.22e-04200303d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellControl_saline-Endothelial-Endothelial-Alv_Gen_Intermediate|Control_saline / Treatment groups by lineage, cell group, cell type

PLK2 MARCKSL1 MARCKS

3.22e-04200303041a34080120c9f613373c20dcc366292f558040
Drugdodecanethiol

SCN11A CDS1 RBM19

8.87e-0633283CID000008195
Diseaseganglion cell inner plexiform layer thickness measurement

COBL STOX2

3.47e-0428292EFO_0600005
Diseasemacula measurement

NUMB COBL STOX2

8.36e-04189293EFO_0008375
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

DLG2 RASAL2

1.07e-0349292DOID:0060037 (implicated_via_orthology)
Diseaseretinal layer thickness measurement

COBL STOX2

1.59e-0360292EFO_0600002
Diseaseinsulin measurement

MYRIP COBL DLG2

2.25e-03267293EFO_0004467
Diseasegut microbiome measurement, bone density

DLG2 CPSF2

2.67e-0378292EFO_0003923, EFO_0007874
Diseasesquamous cell lung carcinoma, family history of lung cancer

COBL DLG2

3.17e-0385292EFO_0000708, EFO_0006953
Diseasevisual epilepsy (biomarker_via_orthology)

MARCKSL1 MARCKS

3.54e-0390292DOID:11832 (biomarker_via_orthology)
Diseasemultisite chronic pain

NUMB PLK2

3.94e-0395292EFO_0010100
Diseasebone fracture

DOK6 COBL

5.42e-03112292EFO_0003931
Diseaseplatelet component distribution width

DOK6 PWWP2A NUMB SCN11A

6.07e-03755294EFO_0007984
DiseaseMyopia

DLG2 SCN11A CPSF2

6.26e-03385293HP_0000545
DiseaseMammary Carcinoma, Animal

CDS1 PLK2

8.57e-03142292C1257925
DiseaseAnimal Mammary Neoplasms

CDS1 PLK2

8.57e-03142292C0024667
Diseasecarotid artery intima media thickness

GMNC FUT10 MAS1

9.59e-03450293EFO_0007117

Protein segments in the cluster

PeptideGeneStartEntry
KTKGKRFTYKFNFSK

ERFL

111

A0A1W2PQ73
GFFASGFKRAFKIKD

CDS1

371

Q92903
EGSRKGSFFKQAKKS

CPSF2

446

Q9P2I0
GFRSSFRKLFKKKNG

ARHGEF33

816

A8MVX0
GKFFLLKRFNKEKLG

ALDH3A2

451

P51648
KFLKAKFGLGATRDF

DPY19L3

376

Q6ZPD9
GKKSRFGKKRNSNFS

ERCC6

1326

Q03468
CSLKFTKDGKFRKFG

RBM19

31

Q9Y4C8
TKDGKFRKFGFIGFK

RBM19

36

Q9Y4C8
FFVGSSKKKRFKESL

MAS1

281

P04201
RRYKNQKFGFGGKKK

EBNA1BP2

241

Q99848
GFFSKRLKGSIKRTK

RASAL2

41

Q9UJF2
TKRKSKFSGFGKIFK

PHACTR4

31

Q8IZ21
KPFKLSGLSFKRNRK

MARCKSL1

96

P49006
FKKASSKGPRRLEKF

DOK6

31

Q6PKX4
SFLKKEGLTFNRKRK

FUT10

61

Q6P4F1
KKFLGFFKVNKRSNS

COBL

246

O75128
KRFSFKKSFKLSGFS

MARCKS

156

P29966
GSFNDKRKKSFIFSR

DLG2

626

Q15700
IIKKSSGFSGKGFKF

DDX46

766

Q7L014
KAERKFFKGFFGKTG

NUMB

66

P49757
FQSRFNKKRKGLYRK

PWWP2A

716

Q96N64
FSKAYGKFRKGKRKS

GMNC

136

A6NCL1
FGGFRKRKKAKSSVS

SLCO6A1

61

Q86UG4
NQLKFRKKKLRFGRS

SETD1A

1561

O15047
SLKRFANFTGGKIAK

USP42

316

Q9H9J4
KQSKKFGLKLFRLSF

STOX2

261

Q9P2F5
FGLKLFRLSFKKDKT

STOX2

266

Q9P2F5
KFTDKKFSLKLNGGR

SNRPGP15

11

A8MWD9
FGNKKRKSFFLRESG

SCN11A

461

Q9UI33
KNFFKKAAAALFGGK

PLK2

361

Q9NYY3
KSRFKRFGSAKVLKN

MYRIP

126

Q8NFW9