Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1E CACNA1I

3.42e-0814504GO:0008331
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

1.23e-069503GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

1.23e-069503GO:0099626
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

MAP3K9 MAP3K10 MAP3K21

3.20e-0612503GO:0004706
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1E CACNA1I

5.25e-0646504GO:0005245
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

1.75e-05129505GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

3.73e-05151505GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

3.85e-05152505GO:0022843
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

MAP3K9 MAP3K10 MAP3K21

4.14e-0527503GO:0004709
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

9.05e-05182505GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

9.53e-05184505GO:0022832
GeneOntologyMolecularFunctiongated channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

1.79e-04334506GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

2.07e-04343506GO:0005261
GeneOntologyMolecularFunctionamide binding

CACNA1A CACNA1B GRIN2A SARDH EPDR1

8.89e-04299505GO:0033218
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

9.64e-04459506GO:0005216
GeneOntologyMolecularFunctionactin binding

XIRP1 IMPACT SNTG1 LASP1 NEB SPATA31C1

1.20e-03479506GO:0003779
GeneOntologyMolecularFunctionchannel activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

1.91e-03525506GO:0015267
GeneOntologyMolecularFunctioncullin family protein binding

KLHL9 KLHL13

1.92e-0326502GO:0097602
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

1.93e-03526506GO:0022803
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN2A GRM6

2.07e-0327502GO:0008066
GeneOntologyMolecularFunctionamyloid-beta binding

CACNA1A CACNA1B GRIN2A

2.13e-03102503GO:0001540
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A CACNA1B CACNA1E ABCA13 ABCB6 CACNA1I GRIN2A LASP1 CHRND

2.38e-031180509GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A LASP1 CHRND

3.42e-03793507GO:0015075
GeneOntologyMolecularFunctiontransporter activity

CACNA1A CACNA1B CACNA1E ABCA13 ABCB6 CACNA1I GRIN2A LASP1 CHRND

4.29e-031289509GO:0005215
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

GRIN2A CHRND

5.20e-0343502GO:0005231
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

6.00e-03465505GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

6.06e-03664506GO:0008324
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA13 ABCB6

6.70e-0349502GO:0140359
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

1.08e-0748505GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

1.08e-0748505GO:1902656
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1A CACNA1B EPO CACNA1E CACNA1I GRIN2A GRM6

8.81e-07217507GO:0097553
GeneOntologyBiologicalProcesscalcium ion import

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

3.91e-0698505GO:0070509
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

2.38e-05142505GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

2.38e-05142505GO:0098659
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1A CACNA1B EPO CACNA1E CACNA1I GRIN2A GRM6

4.19e-05392507GO:0070588
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1A CACNA1B EPO CACNA1E CACNA1I GRIN2A GRM6

2.13e-04509507GO:0006816
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A CACNA1B CACNA1E CACNA1I GRM6

2.32e-04230505GO:0098739
GeneOntologyBiologicalProcessresponse to pain

CACNA1A CACNA1B CACNA1E

2.57e-0451503GO:0048265
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A CACNA1B EPO CACNA1E ABCB6 CACNA1I GRIN2A LASP1 GRM6 CHRND

2.91e-0411155010GO:0034220
GeneOntologyBiologicalProcessresponse to amyloid-beta

CACNA1A CACNA1B GRIN2A

4.37e-0461503GO:1904645
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1B CACNA1E CACNA1I

4.39e-0646504GO:0005891
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A CACNA1B CACNA1E SNTG1 ITGA6 ABCB6 CACNA1I GRIN2A ITGA1 CHRND

1.38e-057855010GO:0098797
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CACNA1B CACNA1E CACNA1I

2.79e-0573504GO:0034704
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A CACNA1B CACNA1E ABCB6 CACNA1I GRIN2A CHRND

2.32e-04523507GO:1902495
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A CHRND

2.73e-04378506GO:0034702
GeneOntologyCellularComponenttransporter complex

CACNA1A CACNA1B CACNA1E ABCB6 CACNA1I GRIN2A CHRND

3.15e-04550507GO:1990351
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1A CACNA1E GRIN2A ADGRL2 GRM6 CHRND

3.94e-04405506GO:0045211
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1B CACNA1E CACNA1I

2.39e-03235504GO:0034703
GeneOntologyCellularComponentmembrane protein complex

CACNA1A CACNA1B CACNA1E SNTG1 ITGA6 ABCB6 CACNA1I GRIN2A ITGA1 CHRND

2.53e-0314985010GO:0098796
GeneOntologyCellularComponentsynaptic membrane

CACNA1A CACNA1E GRIN2A ADGRL2 GRM6 CHRND

2.57e-03583506GO:0097060
GeneOntologyCellularComponentintegrin complex

ITGA6 ITGA1

2.66e-0332502GO:0008305
GeneOntologyCellularComponentpostsynapse

DOCK1 CACNA1A CACNA1E GRIN2A LASP1 ADGRL2 GRM6 CHRND

2.67e-031018508GO:0098794
DomainVDCCAlpha1

CACNA1A CACNA1B CACNA1E CACNA1I

9.43e-0910504IPR002077
DomainSH3_9

DOCK1 MAP3K9 MAP3K10 LASP1 NEB MAP3K21

5.99e-0878506PF14604
DomainMLK1/MLK2/MLK4

MAP3K9 MAP3K10 MAP3K21

7.21e-084503IPR016231
DomainMAP3K10

MAP3K9 MAP3K10 MAP3K21

7.21e-084503IPR015785
DomainVDCC_a1su_IQ

CACNA1A CACNA1B CACNA1E

6.27e-077503IPR014873
DomainGPHH

CACNA1A CACNA1B CACNA1E

6.27e-077503PF16905
DomainGPHH_dom

CACNA1A CACNA1B CACNA1E

6.27e-077503IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

6.27e-077503SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

6.27e-077503PF08763
DomainSH3

DOCK1 MYO15B MAP3K9 MAP3K10 LASP1 NEB MAP3K21

1.64e-06216507SM00326
DomainSH3

DOCK1 MYO15B MAP3K9 MAP3K10 LASP1 NEB MAP3K21

1.64e-06216507PS50002
DomainSH3_domain

DOCK1 MYO15B MAP3K9 MAP3K10 LASP1 NEB MAP3K21

1.86e-06220507IPR001452
DomainChannel_four-helix_dom

CACNA1A CACNA1B CACNA1E CACNA1I

1.62e-0557504IPR027359
Domain-

CACNA1A CACNA1B CACNA1E CACNA1I

1.62e-05575041.20.120.350
DomainNEBU

LASP1 NEB

4.20e-054502SM00227
DomainNebulin

LASP1 NEB

4.20e-054502PF00880
DomainNebulin

LASP1 NEB

4.20e-054502IPR013998
DomainNEBULIN

LASP1 NEB

4.20e-054502PS51216
DomainNebulin_repeat

LASP1 NEB

4.20e-054502IPR000900
DomainSH3_1

DOCK1 MAP3K10 LASP1 NEB MAP3K21

7.56e-05164505PF00018
DomainIon_trans_dom

CACNA1A CACNA1B CACNA1E CACNA1I

2.44e-04114504IPR005821
DomainIon_trans

CACNA1A CACNA1B CACNA1E CACNA1I

2.44e-04114504PF00520
DomainIntegrin_alpha_C_CS

ITGA6 ITGA1

8.23e-0416502IPR018184
DomainIntegrin_alpha-2

ITGA6 ITGA1

1.05e-0318502IPR013649
DomainIntegrin_alpha2

ITGA6 ITGA1

1.05e-0318502PF08441
DomainIntegrin_alpha

ITGA6 ITGA1

1.05e-0318502IPR000413
DomainINTEGRIN_ALPHA

ITGA6 ITGA1

1.05e-0318502PS00242
DomainInt_alpha_beta-p

ITGA6 ITGA1

1.17e-0319502IPR013519
DomainInt_alpha

ITGA6 ITGA1

1.17e-0319502SM00191
DomainFG_GAP

ITGA6 ITGA1

1.57e-0322502PS51470
DomainSH3_2

MYO15B MAP3K9 MAP3K10

1.58e-0386503IPR011511
DomainSH3_2

MYO15B MAP3K9 MAP3K10

1.58e-0386503PF07653
DomainFG-GAP

ITGA6 ITGA1

1.87e-0324502PF01839
DomainFG-GAP

ITGA6 ITGA1

1.87e-0324502IPR013517
DomainIntegrin_dom

ITGA6 ITGA1

2.03e-0325502IPR032695
Domain-

KLHL9 KLHL13

2.36e-03275022.130.10.80
DomainGal_Oxidase_b-propeller

KLHL9 KLHL13

3.73e-0334502IPR015916
DomainANF_lig-bd_rcpt

GRIN2A GRM6

4.41e-0337502IPR001828
DomainANF_receptor

GRIN2A GRM6

4.41e-0337502PF01094
DomainPeripla_BP_I

GRIN2A GRM6

4.89e-0339502IPR028082
DomainBTB-kelch_protein

KLHL9 KLHL13

5.91e-0343502IPR017096
DomainSer-Thr/Tyr_kinase_cat_dom

MAP3K9 MAP3K10 MAP3K21

6.00e-03138503IPR001245
DomainAAA+_ATPase

ABCA13 ABCB6 DNAH8

6.75e-03144503IPR003593
DomainAAA

ABCA13 ABCB6 DNAH8

6.75e-03144503SM00382
DomainP-loop_NTPase

MYO15B ABCA13 ABCB6 CHD6 DNAH8 ARL5A SEPTIN6

7.06e-03848507IPR027417
DomainABC_tran

ABCA13 ABCB6

7.32e-0348502PF00005
DomainABC_TRANSPORTER_2

ABCA13 ABCB6

7.32e-0348502PS50893
DomainABC_TRANSPORTER_1

ABCA13 ABCB6

7.62e-0349502PS00211
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1B CACNA1E CACNA1I

3.83e-0723384M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1B CACNA1E CACNA1I

5.45e-0725384M47948
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1E

2.94e-0611383M47958
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

2.94e-0611383MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

2.94e-0611383M26913
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

EPO CSF3R ANPEP ITGA6 ITGA1

3.41e-0687385M6856
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAP3K9 MAP3K10 MAP3K21

3.91e-0612383M47929
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

1.09e-04178385M2890
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1A CACNA1B CACNA1E GRIN2A CHRND

2.41e-04211385MM14502
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1B CACNA1E

2.70e-0447383M19708
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1A CACNA1B CACNA1E GRIN2A CHRND

7.43e-04270385M15514
PathwayKEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY

EPO CSF3R

9.38e-0417382M47905
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

CACNA1A CACNA1B GRIN2A

9.87e-0473383MM16641
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E CACNA1I

4.74e-10950416382099
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

2.80e-09350338996073
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1B CACNA1E

2.80e-09350324523520
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1B CACNA1E

1.12e-08450332616470
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1B CACNA1E

1.12e-08450337141091
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1B CACNA1E

2.79e-0855038825650
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1B CACNA1E

2.79e-08550311296258
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1B CACNA1E

2.79e-08550315451373
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1B CACNA1E

5.57e-08650335324301
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1B CACNA1E

5.57e-0865039238069
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1B CACNA1E

5.57e-08650312827191
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1B CACNA1E

9.75e-08750335176221
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1B CACNA1E CACNA1I

1.56e-07850328330839
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNA1B CACNA1E CACNA1I

2.69e-073850430786075
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1B CACNA1E

1.26e-061550320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1B CACNA1E

1.26e-061550324453333
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

2.03e-06250215610184
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

2.03e-06250223426690
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

2.03e-06250216381801
Pubmed

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.

MAP3K9 MAP3K10

2.03e-06250211416147
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

2.03e-06250238155373
Pubmed

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

CACNA1B CACNA1E

2.03e-06250212074836
Pubmed

Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.

MAP3K9 MAP3K10

2.03e-0625028477742
Pubmed

Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.

CACNA1A CACNA1B

2.03e-06250215050706
Pubmed

Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.

MAP3K9 MAP3K10

2.03e-0625028536694
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

2.03e-06250223376566
Pubmed

Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.

CACNA1A CACNA1B

6.07e-06350229466725
Pubmed

Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.

MAP3K9 MAP3K10

6.07e-06350218414056
Pubmed

Responses of endothelial cell and astrocyte matrix-integrin receptors to ischemia mimic those observed in the neurovascular unit.

ITGA6 ITGA1

6.07e-06350218032737
Pubmed

Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.

KLHL9 KLHL13

6.07e-06350233872809
Pubmed

Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.

CACNA1A CACNA1B

6.07e-06350224394417
Pubmed

Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.

CACNA1A CACNA1B

6.07e-06350229208674
Pubmed

Timing of gene expression and oolemma localization of mouse alpha6 and beta1 integrin subunits during oogenesis.

ITGA6 ITGA1

6.07e-0635029698453
Pubmed

Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.

CACNA1A CACNA1B

6.07e-06350226507659
Pubmed

Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.

MAP3K9 MAP3K10

6.07e-0635028195146
Pubmed

Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.

CACNA1A CACNA1B

1.21e-05450226283199
Pubmed

Interactions of Rabconnectin-3 with Cav2 calcium channels.

CACNA1A CACNA1B

1.21e-05450231253182
Pubmed

Collagen type IV, laminin, alpha-smooth muscle actin (alphaSMA), alpha1 and alpha6 integrins expression in the liver with metastases from malignant gastrointestinal tumours.

ITGA6 ITGA1

1.21e-05450215679046
Pubmed

A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C.

CACNA1A CACNA1B

1.21e-05450215728831
Pubmed

G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.

CACNA1A CACNA1B

1.21e-05450215953418
Pubmed

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

XIRP1 NEB

1.21e-05450223985323
Pubmed

The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.

CACNA1A CACNA1B

1.21e-05450225483588
Pubmed

Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.

CACNA1A CACNA1B

2.02e-05550216787652
Pubmed

Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.

KLHL9 KLHL13

2.02e-05550231515271
Pubmed

A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes.

CACNA1A GRIN2A

3.03e-05650221883149
Pubmed

beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.

CACNA1A CACNA1B

3.03e-05650210328888
Pubmed

The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line.

ITGA6 ITGA1

3.03e-0565021690718
Pubmed

Mechanism of beta 1-integrin-mediated hepatoma cell growth involves p27 and S-phase kinase-associated protein 2.

ITGA6 ITGA1

3.03e-05650212883474
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1A GRIN2A GRM6

3.80e-054550325979088
Pubmed

Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.

ITGA6 ITGA1

4.23e-05750211767049
Pubmed

Integrin expression patterns during early limb muscle development in the mouse.

ITGA6 ITGA1

4.23e-05750214516674
Pubmed

Developmental regulation of integrin expression at the time of implantation in the mouse embryo.

ITGA6 ITGA1

5.64e-0585028306881
Pubmed

Expression of beta 1 integrin complexes on the surface of unfertilized mouse oocyte.

ITGA6 ITGA1

5.64e-0585027691492
Pubmed

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

ITGA6 ITGA1

5.64e-0585029553049
Pubmed

Characterization of integrin engagement during defined human embryonic stem cell culture.

ITGA6 ITGA1

7.25e-05950219933311
Pubmed

Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.

ITGA6 ITGA1

7.25e-0595021693624
Pubmed

Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains.

ITGA6 ITGA1

7.25e-05950210094488
Pubmed

Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.

MAP3K9 MAP3K10

7.25e-05950214504284
Pubmed

Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells.

ITGA6 ITGA1

7.25e-05950225808196
Pubmed

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.

CACNA1B GRIN2A

9.05e-051050218054859
Pubmed

A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

KLHL9 KLHL13

9.05e-051050217543862
Pubmed

Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.

ITGA6 ITGA1

1.10e-041150215739233
Pubmed

Immunolocalization of extracellular matrix components and integrins during mouse liver development.

ITGA6 ITGA1

1.10e-041150215368439
Pubmed

Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.

KLHL9 KLHL13

1.10e-041150214528312
Pubmed

The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

KLHL9 KLHL13

1.32e-041250219995937
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A CACNA1B CACNA1E GRIN2A SEPTIN6

1.41e-0434750517114649
Pubmed

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.

ITGA6 ITGA1

1.56e-041350220563599
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

CACNA1A CACNA1B

1.82e-041450221228161
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

CACNA1E ARMC3 SNTG1 CACNA1I

1.95e-0419950423382691
Pubmed

MAP3Ks as central regulators of cell fate during development.

MAP3K9 MAP3K10

2.10e-041550218855897
Pubmed

Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.

ITGA6 ITGA1

2.10e-041550215366018
Pubmed

Integrin requirement for hippocampal synaptic plasticity and spatial memory.

ITGA6 ITGA1

2.40e-041650212904471
Pubmed

USP25 regulates Wnt signaling by controlling the stability of tankyrases.

KLHL9 KLHL13

2.40e-041650228619731
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

KLHL9 KLHL13 LASP1

2.72e-048750337495603
Pubmed

Identification of substrates of SMURF1 ubiquitin ligase activity utilizing protein microarrays.

IMPACT MAP3K9 MAP3K10

2.72e-048750320804422
Pubmed

Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis.

ITGA6 ITGA1

3.05e-041850219686679
Pubmed

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.

DOCK1 XIRP1

3.41e-041950224564958
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

CACNA1A CACNA1E XIRP1 SEPTIN6

3.55e-0423350437704626
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

GRIN2A ITGA1

4.59e-042250235245678
Pubmed

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

EPO CSF3R

4.59e-04225029811459
Pubmed

A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.

KLHL9 KLHL13

5.03e-042350233130828
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ITGA6 ITGA1

5.03e-042350223152823
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIN2A GRM6

5.48e-042450235746896
Pubmed

Dimerization quality control ensures neuronal development and survival.

KLHL9 KLHL13

5.48e-042450230190310
Pubmed

Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.

CACNA1A CACNA1B

5.48e-042450222534482
Pubmed

A human MAP kinase interactome.

DOCK1 MAP3K10 CHD6 NEB MAP3K21

6.59e-0448650520936779
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

CSF3R MAP3K10 ITGA6 ARL5A

6.71e-0427650428319085
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA6 ITGA1

6.95e-042750231541017
Pubmed

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.

SNTG1 NEB

6.95e-042750218468998
Pubmed

Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.

ITGA6 ITGA1

8.59e-043050232562661
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

MBTPS1 ITGA6

9.17e-043150211431694
Pubmed

Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.

CACNA1B CACNA1E

9.77e-043250219320717
Pubmed

A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.

INHBB CACNA1I

9.77e-043250230926747
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A CACNA1B CACNA1E

1.07e-0313950316985003
Pubmed

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis.

INHBB ITGA6

1.24e-033650238078651
Pubmed

Ion channel expression in the developing enteric nervous system.

CACNA1A CACNA1B

1.31e-033750225798587
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

KLHL9 KLHL13 CHD6

1.41e-0315350310718198
CytobandEnsembl 112 genes in cytogenetic band chr2q23

NEB ARL5A

1.55e-0353502chr2q23
CytobandEnsembl 112 genes in cytogenetic band chrXq24

KLHL13 SEPTIN6

3.57e-0381502chrXq24
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1B CACNA1E CACNA1I

2.15e-0726374253
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K9 MAP3K10 MAP3K21

1.55e-0524373654
GeneFamilyCD molecules|Integrin alpha subunits

ITGA6 ITGA1

6.11e-04183721160
GeneFamilyKelch like|BTB domain containing

KLHL9 KLHL13

3.33e-0342372617
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO15B PTPN14

4.69e-03503721293
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CSF3R ANPEP ITGA6 ITGA1

8.32e-03394374471
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B SNTG1 GRIN2A DNAH8

6.77e-07148505d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B SNTG1 GRIN2A ADGRL2

2.83e-06198505c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B SNTG1 GRIN2A ADGRL2

2.83e-061985056d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B SNTG1 GRIN2A ADGRL2

2.83e-061985054ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1A CACNA1B SNTG1 GRIN2A ADGRL2

2.97e-0620050548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A ABCA13 SNTG1 GRIN2A

2.18e-05146504c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B SNTG1 DNAH8

2.43e-051505040205318a870e091add66ee4305747dda9f51510d
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSF3R ABCA13 MAP3K9 EPDR1

2.69e-05154504d55fb73461885e1e02061a344ff89624ef4de487
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSF3R ABCA13 MAP3K9 EPDR1

2.69e-0515450443735f7c58cac51855ded486ee8d8729a1b9909e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DOCK1 INHBB SNTG1 ITGA1

2.90e-051575042c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B SNTG1 DNAH8

3.05e-051595045335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNTG1 ADGRL2 MAP3K21 MOCOS

3.28e-05162504285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1B CACNA1E SNTG1

3.69e-05167504c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1B CACNA1E SNTG1

3.87e-05169504b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF3R ABCA13 MAP3K9 LASP1

4.05e-05171504ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF3R ABCA13 MAP3K9 LASP1

4.05e-0517150497ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D175|Adult / Lineage, Cell type, age group and donor

MYO15B INHBB ITGA6 ITGA1

4.63e-05177504c9f269765c7d5d29caab75910e51645606ed562e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

4.73e-051785043b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

4.94e-051805041f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNTG1 ADGRL2 MAP3K21 MOCOS

4.94e-05180504788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNTG1 ADGRL2 MAP3K21 MOCOS

5.16e-05182504f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 ARMC3 INHBB MUC4

5.38e-0518450407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB EXOC3L1 ADGRL2 MOCOS

5.50e-05185504512a195ebbae445afe3722a3943020080daf2f3c
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA6 EXOC3L1 ITGA1 ADGRL2

5.61e-05186504f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN14 ITGA6 ITGA1 ADGRL2

5.61e-0518650441f1674afc17661eccaa779cdeb663db5e45685d
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN14 ITGA6 ITGA1 ADGRL2

5.61e-05186504aa006650cf21a2c51dfe1091681f67fdad939107
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA6 EXOC3L1 ITGA1 ADGRL2

5.61e-051865042b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA6 EXOC3L1 ADGRL2 DNAH8

5.73e-05187504e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

5.73e-05187504f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellE17.5-Endothelial-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA6 EXOC3L1 ADGRL2 DNAH8

5.73e-0518750461b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA6 EXOC3L1 ITGA1 ADGRL2

5.85e-05188504117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

5.97e-05189504c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL13 SNTG1 MAP3K21 MOCOS

5.97e-0518950490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

5.97e-05189504b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915047b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915049f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP251 ARMC3 ABCA13 MUC4

6.22e-0519150428caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915045129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP251 ARMC3 ABCA13 MUC4

6.22e-0519150415b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504b78547dae8328244a47c83346447bdd787efbcae
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915049d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

CFAP251 ARMC3 ABCA13 MUC4

6.22e-05191504cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915046228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP251 ARMC3 ABCA13 MUC4

6.22e-051915041c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CACNA1B CACNA1E CACNA1I GRIN2A

6.35e-051925044c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.35e-051925049cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.35e-05192504eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB EXOC3L1 ITGA1 ADGRL2

6.48e-051935045d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB EXOC3L1 ITGA1 ADGRL2

6.48e-0519350495e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB EXOC3L1 ITGA1 ADGRL2

6.48e-0519350497c0730aad9135ac681250b3871cc094a28f80a7
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ITGA6 EXOC3L1 ITGA1 ADGRL2

6.48e-05193504979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP251 ARMC3 ABCA13 MUC4

6.61e-05194504756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 ITGA6 EXOC3L1 ADGRL2

6.61e-051945040b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

INHBB ITGA6 ITGA1 ADGRL2

6.61e-05194504ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

6.61e-051945044a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

INHBB ITGA6 ITGA1 ADGRL2

6.61e-05194504cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.61e-0519450443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CACNA1A CSF3R ABCA13 GRM6

6.74e-05195504d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 EXOC3L1 ITGA1 ADGRL2

6.74e-051955048ab45ab94c722c4aef0229ee1121cd744bf659dd
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CACNA1A CSF3R ABCA13 GRM6

6.74e-0519550419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

6.74e-0519550479dc031258579ea328181dda33710dd897f1064a
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPN14 ITGA6 ITGA1 ADGRL2

6.74e-05195504094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SNTG1 GRIN2A ADGRL2

6.88e-05196504676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.88e-05196504af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 ARMC3 ABCA13 MUC4

6.88e-051965046d02d494196e3f857d53eea46d9419690d43beca
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

7.01e-0519750491637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CACNA1E ABCA13 SUPT5H NEB

7.01e-0519750470704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

7.01e-0519750422c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

7.01e-051975043bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.01e-0519750481718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 KLHL13 ADGRL2 MUC4

7.01e-051975041e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

7.01e-0519750487db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.15e-0519850445419f2804b4be79bae6632e71c54e1af482d115
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.15e-0519850440c2171e79f578c9116d872c189f953dc61d052d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SNTG1 GRIN2A ADGRL2

7.15e-051985040ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ARMC3 ABCA13 MUC4

7.15e-05198504d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.29e-05199504793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1B CACNA1E CACNA1I GRIN2A

7.44e-052005042f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellParenchyma_COVID-19-Endothelial-TX-Capillary|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-052005046c0498a5868891e8e22c03469d00669b20249b1a
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-05200504a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MBTPS1 GAPVD1 ABCA13 MUC4

7.44e-0520050464462a18afca3c1a8548a857924b8166058bf958
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFAP251 ARMC3 ABCA13 MUC4

7.44e-05200504f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1B CACNA1E CACNA1I GRIN2A

7.44e-05200504bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-052005043ef7b7728615710c691aed8977e2582f19692cf9
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-052005047020045b933cb104fb99b79524cb0d4734b8636d
ToppCellBiopsy_Control_(H.)-Epithelial-Differentiating_Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CFAP251 ARMC3 ABCA13 MUC4

7.44e-05200504a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-05200504e9913511a129bb3cee85e7ebf565b951dab91542
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1B CACNA1E CACNA1I GRIN2A

7.44e-05200504dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 EXOC3L1 ITGA1 ADGRL2

7.44e-05200504707148e01e961097819a05437a842b7d3bf72b0a
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

XIRP1 ANPEP DNAH8

2.85e-041145032cc5d2da5573650c5232a01e2d2128082c4bffcb
Drug3,4-dihydroquinazoline

CACNA1A CACNA1B CACNA1E CACNA1I

2.83e-106494CID000583065
DrugAC1L2VU3

CACNA1A CACNA1B CACNA1E CACNA1I

9.25e-0912494CID000129572
DrugDantrolene-13C3

CACNA1A CACNA1B CACNA1E MBTPS1 CACNA1I GRIN2A GRM6

2.52e-08145497CID000002951
Drugbutamben

CACNA1A CACNA1B CACNA1E CACNA1I

2.54e-0815494CID000002482
Drugpentasulfane

CACNA1A CACNA1B CACNA1E CACNA1I

3.38e-0816494CID000448216
DrugAC 110

CACNA1A CACNA1B CACNA1E

3.74e-084493CID000022860
Druggabapentin

CACNA1A CACNA1B CACNA1E ANPEP CACNA1I GRIN2A GRM6

7.24e-08169497CID000003446
Drugalpha-sialylcholesterol

CACNA1A CACNA1B CACNA1E

1.86e-076493CID000133976
DrugAPMPA

CACNA1A CACNA1B CACNA1E

3.26e-077493CID000512300
DrugDCG-IV

CACNA1A CACNA1B CACNA1E GRIN2A GRM6

3.52e-0768495CID000115114
Drugnimodipine

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A GRM6

6.71e-07145496CID000004497
DrugCNS 1145

CACNA1A CACNA1B CACNA1E CACNA1I

7.40e-0733494CID000190902
DrugIHC-64

CACNA1A CACNA1B CACNA1E CACNA1I

7.40e-0733494CID000162753
Drug3-7a

CACNA1A CACNA1B CACNA1E GRIN2A

1.06e-0636494CID011987860
Drug3,4-diaminopyridine

CACNA1A CACNA1B CACNA1E CHRND

1.32e-0638494CID000005918
Drughexachlorophene

CACNA1A CACNA1B CACNA1E GRIN2A GRM6

1.43e-0690495CID000003598
Drug2-amino-4-phosphonobutyric acid

CACNA1A CACNA1B CACNA1E GRIN2A GRM6

1.51e-0691495CID000002207
Drugleys

CACNA1A CACNA1B CACNA1E

1.53e-0611493CID000484683
Drugriluzole

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A GRM6

1.95e-06174496CID000005070
Drugloperamide

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

3.08e-06105495CID000003954
Drugbaclofen

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A GRM6

3.34e-06191496CID000002284
Drugtetradotoxin

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A EPDR1 GRM6 CHRND

3.35e-06428498CID000020382
Drugnorcepharadione B

CACNA1B CACNA1E

4.54e-062492CID000189168
Drugaristolactam AII

CACNA1B CACNA1E

4.54e-062492CID000148657
Drugalkosin

CACNA1B CACNA1E

4.54e-062492CID005488638
Drugpiperolactam A

CACNA1B CACNA1E

4.54e-062492CID003081016
Druglamotrigine

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

5.02e-06116495CID000003878
DrugVerapamil

CACNA1A CACNA1B CACNA1I

5.14e-0616493DB00661
DrugDPCPX

CACNA1A CACNA1B CACNA1E GRIN2A GRM6

5.23e-06117495CID000001329
DrugCinildipine

CACNA1A CACNA1B CACNA1E CACNA1I

6.40e-0656494CID000002752
Drugnefiracetam

CACNA1A CACNA1B CACNA1E CHRND

6.40e-0656494CID000071157
Drugnilvadipine

CACNA1A CACNA1B CACNA1E CACNA1I

8.45e-0660494CID000004494
DrugN6-Me-dAdo

CACNA1A CACNA1B CACNA1E

8.86e-0619493CID000168948
Drugpranidipine

CACNA1A CACNA1B CACNA1E

8.86e-0619493CID006436048
DrugGR 64349

CACNA1B CACNA1E MBTPS1

8.86e-0619493CID003036081
DrugIAA-94

CACNA1A CACNA1B CACNA1E CACNA1I

9.03e-0661494CID000003667
Drugverapamil

CACNA1A CACNA1B EPO CACNA1E ABCA13 ABCB6 CACNA1I CHRND

9.03e-06490498CID000002520
Druglercanidipine

CACNA1A CACNA1B CACNA1E CACNA1I

1.03e-0563494CID000065866
DrugAC1L1TJF

CACNA1A CACNA1B CACNA1E CACNA1I

1.24e-0566494CID000003377
Druggallopamil

CACNA1A CACNA1B CACNA1E CACNA1I

1.31e-0567494CID000001234
DrugAC1L2AC7

CACNA1A CACNA1B CACNA1E CACNA1I

1.48e-0569494CID000068733
Drugnicardipine

CACNA1A CACNA1B CACNA1E CACNA1I CHRND

1.49e-05145495CID000004473
DrugLY320135

CACNA1A CACNA1B CACNA1E

1.61e-0523493CID005311257
Drugalpha-conotoxin SI

CACNA1A CACNA1B CACNA1E

1.61e-0523493CID000163979
DrugBarium

CACNA1A CACNA1B CACNA1E CACNA1I

1.75e-0572494ctd:D001464
DrugCAS 298-57-7

CACNA1A CACNA1B CACNA1E CACNA1I

1.85e-0573494CID000002761
Drugdopamine

CACNA1A CACNA1B CACNA1E ANPEP SUPT5H GRIN2A GRM6 SNRPE CHRND

1.88e-05715499CID000000681
Drugprocaine

CACNA1A CACNA1B CACNA1E CACNA1I CHRND

1.93e-05153495CID000004914
Drug1,3-dipropylxanthine

CACNA1A CACNA1B CACNA1E GRM6

1.95e-0574494CID000169317
Drugethosuximide

CACNA1A CACNA1B CACNA1E CACNA1I

1.95e-0574494CID000003291
Drugnisoldipine

CACNA1A CACNA1B CACNA1E CACNA1I

2.40e-0578494CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1A CACNA1B CACNA1E CACNA1I

2.53e-0579494CID005287890
DrugGDP-b-S

CACNA1A CACNA1B EPO MBTPS1 GRM6

2.54e-05162495CID000643998
DrugmAHP

CACNA1A CACNA1B CACNA1E

2.64e-0527493CID000220531
Drugeniluracil

CACNA1A CACNA1B CACNA1E

2.64e-0527493CID000043157
DrugNSC755875

CACNA1B CACNA1E ANPEP GRIN2A CHRND

2.77e-05165495CID000002215
Drugphorbol acetate myristate

CACNA1A CACNA1B EPO CACNA1E MBTPS1 ANPEP INHBB ITGA6 CACNA1I ITGA1 MUC4 MOCOS

3.04e-0513994912CID000004792
Druglavendustin A

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

3.29e-05171495CID000003894
DrugIPSP

CACNA1B CACNA1E GRIN2A GRM6

3.70e-0587494CID000022083
DrugNSC7524

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A

4.43e-05182495CID000005657
Drug3-aminopropylphosphinic acid

CACNA1A CACNA1B CACNA1E

4.45e-0532493CID006335948
Drugalmagel

CACNA1B CACNA1E

4.52e-055492CID003080942
DrugS 8510

CACNA1A CACNA1B

4.52e-055492CID005488383
DrugAC1L1H6N

CACNA1B XIRP1

4.52e-055492CID000003999
Drugmanidipine

CACNA1A CACNA1B CACNA1E CACNA1I

5.22e-0595494CID000004008
Drugfluspirilene

CACNA1A CACNA1B CACNA1E

5.35e-0534493CID000003396
Drugisotetrandrine

CACNA1A CACNA1B CACNA1E CACNA1I

5.66e-0597494CID000005422
Drughomovanillic acid

CACNA1A CACNA1B CACNA1E CACNA1I

5.66e-0597494CID000001738
Drugnitrendipine

CACNA1A CACNA1B CACNA1E CACNA1I

5.89e-0598494CID000004507
DrugCP-80

CACNA1A CACNA1B CACNA1E

6.36e-0536493CID000452640
Drugisradipine

CACNA1A CACNA1B CACNA1E CACNA1I

6.38e-05100494CID000003784
DrugAminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A

CLEC1B CACNA1I SARDH GRM6 MUC4

6.45e-051974953076_UP
Druggamma-aminobutyric acid

CACNA1A CACNA1B CACNA1E XIRP1 CACNA1I GRIN2A GRM6

6.54e-05474497CID000000119
DrugBAPTA

CACNA1A CACNA1B CACNA1E MBTPS1 GRIN2A GRM6

6.62e-05324496CID000104751
Drug8-cyclopentyltheophylline

CACNA1A CACNA1B CACNA1E

7.49e-0538493CID000001917
DrugAC1L1KS5

CACNA1A CACNA1B CACNA1E MBTPS1 CACNA1I GRM6

7.83e-05334496CID000005631
Drug4-aminopyrrolidine-2,4-dicarboxylate

CACNA1B CACNA1E GRM6

8.11e-0539493CID003331970
DrugGF109203X

CACNA1A CACNA1B CACNA1E MBTPS1 GRM6 MOCOS

8.78e-05341496CID000002396
DrugAC1L1I54

CACNA1A CACNA1B CACNA1E

9.43e-0541493CID000004426
DrugFk 888

CACNA1A CACNA1B CACNA1E

1.01e-0442493CID000107967
Drugphenytoin

CACNA1A CACNA1B CACNA1E CACNA1I SNRPE

1.06e-04219495CID000001775
DrugAC1NBU2S

CACNA1A CACNA1B CACNA1E CACNA1I

1.17e-04117494CID004473765
Drugh PM

CACNA1A CACNA1B ITGA6

1.25e-0445493CID005494424
DrugNiCl2

CACNA1A CACNA1B CACNA1E CACNA1I

1.25e-04119494CID000024385
DrugKN-62

CACNA1A CACNA1B CACNA1E GRIN2A GRM6

1.34e-04230495CID000003838
Drug3-(1H-pyrrole-2-carboxylate

CACNA1A CACNA1B CACNA1E XIRP1 GRM6

1.42e-04233495CID000005114
DrugL024104

CACNA1B CACNA1E ANPEP

1.51e-0448493CID003025353
Drugbepridil

CACNA1A CACNA1B CACNA1E CACNA1I

1.56e-04126494CID000002351
Drugamlodipine

CACNA1A CACNA1B CACNA1E CACNA1I

1.56e-04126494CID000002162
DrugCNQX

CACNA1A CACNA1B GRIN2A GRM6

1.56e-04126494CID000002821
Drugpimozide

CACNA1A CACNA1B CACNA1E CACNA1I

1.61e-04127494CID000016362
DrugKW-3049

CACNA1A CACNA1B CACNA1I

1.71e-0450493CID000002324
Drugcobalt-60

CACNA1A CACNA1B EPO CACNA1E ANPEP CACNA1I

1.82e-04390496CID000061492
Drugcaffeine

CACNA1A CACNA1B CACNA1E CACNA1I GRIN2A GRM6 CHRND

1.88e-04562497CID000002519
Drughaloperidol

CACNA1A CACNA1B CACNA1E ANPEP GRIN2A GRM6

1.93e-04394496CID000003559
DrugD-myo-inositol-1,4,5-triphosphate

CACNA1A CACNA1B CACNA1E MBTPS1 CLEC1B CACNA1I GRM6

2.01e-04568497CID000000806
Drugsmilageninoside

CACNA1B CACNA1E

2.02e-0410492CID000197391
Druglanthanum

CACNA1A CACNA1B CACNA1E CACNA1I

2.09e-04136494CID000023926
Drug13-methoxyibogamine

CACNA1E GRIN2A GRM6

2.15e-0454493CID000065749
Drugguanosine 3',5'-cyclic monophosphoric acid

CACNA1A CACNA1B EPO CACNA1E INHBB CACNA1I GRIN2A

2.21e-04577497CID000000295
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

4.30e-093493DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

1.72e-084493DOID:6364 (implicated_via_orthology)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

1.50e-077493DOID:0050951 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E ITGA6 GRIN2A

7.58e-06163495DOID:1826 (implicated_via_orthology)
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB CHRND

4.04e-056492C1854678
DiseaseMyopathies, Nemaline

KLHL9 NEB

7.52e-058492C0206157
DiseaseBipolar Disorder

CACNA1A CACNA1B ABCA13 IMPACT GRIN2A DNAH8

1.34e-04477496C0005586
Diseasecholangiocarcinoma (biomarker_via_orthology)

EPO MUC4

2.08e-0413492DOID:4947 (biomarker_via_orthology)
DiseasePancytopenia

EPO MOCOS

8.56e-0426492C0030312
Diseasevenous thromboembolism

XIRP1 GRIN2A ADGRL2 MAP3K21 TMPRSS11B

9.77e-04460495EFO_0004286

Protein segments in the cluster

PeptideGeneStartEntry
RNGWNVMDFVVVLTG

CACNA1A

166

O00555
VMQSYLEGVQTGVWQ

EXOC3L1

71

Q86VI1
QQWEGRQVMYQQSSG

EPDR1

46

Q9UM22
MVVGTAWIFLQGVYN

CHRND

481

Q07001
VIGWYRFRRNTQQQM

ABRAXAS2

91

Q15018
VINNTRFLMWDIGGQ

ARL5A

56

Q9Y689
GEDWNEVMYNGIRSQ

CACNA1E

656

Q15878
GQETGIQWNNMYQAL

ABCA13

3731

Q86UQ4
GVYADMWQLQQGQEE

ABCB6

816

Q9NP58
NGLWVIYATEQNNGM

ADGRL2

271

O95490
AGAMENWGLVTYREN

ANPEP

351

P15144
VRGEYGRAWNEVMLQ

ARMC3

816

Q5W041
YLRNGWNVMDFVVVL

CACNA1B

161

Q00975
MLVVRNGQRVWEYLA

CFAP251

721

Q8TBY9
LYQSGGMQWDVAQRS

MUC4

4486

Q99102
LVNWAVQVARGMNYL

MAP3K10

196

Q02779
VLWQMGYTGANVRVA

MBTPS1

201

Q14703
VYFQEQGHGDRWNMV

INHBB

201

P09529
FLYGAMAQDVIWQNA

GAPVD1

1291

Q14C86
NVQQIDDGWMYGTVE

LASP1

231

Q14847
GVSWNTVRYMIGEVQ

DNAH8

4101

Q96JB1
GGYSWNNRCMVEIVQ

KLHL9

551

Q9P2J3
GRVNVVEALQEFWQM

LIX1L

96

Q8IVB5
GNQGLLYDRSWMVVN

MOCOS

606

Q96EN8
VGGAVYVYMNQQGRW

ITGA6

386

P23229
VGAYDWNGTVVMQKA

ITGA1

396

P56199
NVKNVMVVVSRWYGG

IMPACT

256

Q9P2X3
WQRQIMGAYLVRQGQ

MYO15B

531

Q96JP2
AQAMVDIVRALGWNY

GRM6

201

O15303
VVGGYSWNNRCMVEI

KLHL13

591

Q9P2N7
NWLSGVNVVLVMAYG

C1orf43

6

Q9BWL3
QIGFEIRDMWYNLGQ

DOCK1

1061

Q14185
PGNQGYWVQEEMFRR

CHD6

1421

Q8TD26
GWVNIMYNGLDAVAV

CACNA1I

1381

Q9P0X4
MEVGQQAVEVWQGLA

EPO

81

P01588
YQNMGIWVQAENALG

CSF3R

196

Q99062
ILVNWAVQIARGMNY

MAP3K9

241

P80192
GQVYRATWQGQEVAV

MAP3K21

136

Q5TCX8
VLVNWAVQIARGMLY

MAP3K21

236

Q5TCX8
NQQIVYMGWCEAREQ

SNTG1

281

Q9NSN8
GRQAVIYRWNDMGNI

PTPN14

246

Q15678
GVGNLRLGYWNQQMV

SUPT5H

241

O00267
WRQLEQYMGQRGRIQ

SPATA31C1

456

P0DKV0
MRARQYPWGTVQVEN

SEPTIN6

251

Q14141
MFGLEAIWRNGQVVG

SARDH

836

Q9UL12
LGIWSVMQRNYLQGE

CLEC1B

51

Q9P126
NDNVVVTGWGTLYMN

TMPRSS11B

301

Q86T26
IQVWLYEQVNMRIEG

SNRPE

31

P62304
REQIVGGDVQGYRWM

XIRP1

501

Q702N8
NVWNGMIGEVVYQRA

GRIN2A

491

Q12879
AIINVQAIDEGWMYG

NEB

6636

P20929
QAIDEGWMYGTVQRT

NEB

6641

P20929