Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionD-mannose binding

MRC1 LMAN1 CD209

1.24e-0427723GO:0005537
GeneOntologyMolecularFunctioncarbohydrate binding

GALNTL6 MRC1 GALNT10 P4HTM LMAN1 MRC2 CD209

1.26e-04310727GO:0030246
GeneOntologyMolecularFunctionGPI-linked ephrin receptor activity

EPHA5 EPHA7

2.66e-047722GO:0005004
GeneOntologyMolecularFunctionmonosaccharide binding

MRC1 P4HTM LMAN1 CD209

3.86e-0495724GO:0048029
GeneOntologyMolecularFunctiondioxygenase activity

IDO2 P4HTM KDM6B HIF1AN

4.35e-0498724GO:0051213
DomainRicin_B_lectin

GALNTL6 MRC1 GALNT10 MRC2

2.28e-0625714PF00652
DomainRICIN

GALNTL6 MRC1 GALNT10 MRC2

3.66e-0628714SM00458
DomainRICIN_B_LECTIN

GALNTL6 MRC1 GALNT10 MRC2

3.66e-0628714PS50231
DomainRicin_B_lectin

GALNTL6 MRC1 GALNT10 MRC2

4.88e-0630714IPR000772
DomainProt_inh_cystat_CS

CST1 CST4

5.04e-049712IPR018073
DomainC-type_lectin_CS

MRC1 MRC2 CD209

5.83e-0443713IPR018378
DomainCystatin

CST1 CST4

9.18e-0412712IPR027214
DomainCYSTATIN

CST1 CST4

9.18e-0412712PS00287
Domain-

MRC1 MRC2

1.08e-03137122.10.10.10
DomainRECEPTOR_TYR_KIN_V_2

EPHA5 EPHA7

1.26e-0314712PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA5 EPHA7

1.26e-0314712PS00790
DomainEph_TM

EPHA5 EPHA7

1.26e-0314712IPR027936
DomainFN_type2_col-bd

MRC1 MRC2

1.26e-0314712IPR000562
DomainFN2_2

MRC1 MRC2

1.26e-0314712PS51092
DomainTyr_kinase_rcpt_V_CS

EPHA5 EPHA7

1.26e-0314712IPR001426
DomainEPH_lbd

EPHA5 EPHA7

1.26e-0314712SM00615
DomainEphrin_lbd

EPHA5 EPHA7

1.26e-0314712PF01404
DomainEphA2_TM

EPHA5 EPHA7

1.26e-0314712PF14575
DomainTyr_kinase_ephrin_rcpt

EPHA5 EPHA7

1.26e-0314712IPR016257
DomainEphrin_rcpt_lig-bd_dom

EPHA5 EPHA7

1.26e-0314712IPR001090
Domainfn2

MRC1 MRC2

1.26e-0314712PF00040
DomainEPH_LBD

EPHA5 EPHA7

1.26e-0314712PS51550
DomainFN2_1

MRC1 MRC2

1.26e-0314712PS00023
DomainFN2

MRC1 MRC2

1.26e-0314712SM00059
DomainCY

CST1 CST4

1.87e-0317712SM00043
DomainCystatin_dom

CST1 CST4

2.10e-0318712IPR000010
DomainCystatin

CST1 CST4

2.10e-0318712PF00031
DomainC_TYPE_LECTIN_1

MRC1 MRC2 CD209

3.51e-0380713PS00615
DomainLectin_C

MRC1 MRC2 CD209

4.02e-0384713PF00059
DomainCLECT

MRC1 MRC2 CD209

4.02e-0384713SM00034
DomainEphrin_rec_like

EPHA5 EPHA7

4.04e-0325712SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHA5 EPHA7

4.04e-0325712IPR011641
DomainC_TYPE_LECTIN_2

MRC1 MRC2 CD209

4.16e-0385713PS50041
DomainC-type_lectin-like

MRC1 MRC2 CD209

4.30e-0386713IPR001304
DomainHRM

CELSR2 ADGRA2

5.05e-0328712PF02793
DomainSAM_DOMAIN

GAREM2 EPHA5 EPHA7

5.68e-0395713PS50105
Domain-

LMAN1 CELSR2 COL5A3

5.68e-03957132.60.120.200
DomainGlycos_transf_2

GALNTL6 GALNT10

5.79e-0330712PF00535
DomainGlyco_trans_2-like

GALNTL6 GALNT10

5.79e-0330712IPR001173
Domain-

MRC1 MRC2 CD209

6.01e-03977133.10.100.10
DomainC-type_lectin-like/link

MRC1 MRC2 CD209

6.36e-0399713IPR016186
DomainJMJC

KDM6B HIF1AN

6.57e-0332712PS51184
DomainKringle-like

MRC1 MRC2

6.57e-0332712IPR013806
Pubmed

HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors.

MRC1 MRC2 CD209

3.22e-07774316547227
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TGM2 SEMA4B GALNT10 P4HTM LMAN1 CELSR2 P2RX5 MRC2 CLPTM1 ITGA3 MTDH HIF1AN SDF2

1.38e-061201741335696571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4B CELSR2 GAREM2 MTHFR BANP ZNF316 POLRMT PFAS ITGA3 KDM6B ADGRA2 ABTB2

3.56e-061105741235748872
Pubmed

Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1.

MRC1 MRC2

4.47e-06274219224860
Pubmed

Mannose receptor regulation of macrophage cell migration.

MRC1 MRC2

4.47e-06274217596337
Pubmed

[Expression of ephrin-A7 and metadherin and its clinicopathological significances in the benign and malignant lesions of gallbladder].

MTDH EPHA7

4.47e-06274221609571
Pubmed

Association of human mannose receptor in sexual transmission of human immunodeficiency virus in serodiscordant couples.

MRC1 MRC2

4.47e-06274223148569
Pubmed

CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor.

MRC1 MRC2

4.47e-06274215047828
Pubmed

Effect of 1,25-dihydroxyvitamin D3 on the expression of mannose receptor, DC-SIGN and autophagy genes in pulmonary tuberculosis.

MRC1 CD209

4.47e-06274227449998
Pubmed

Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog.

MRC1 CD209

4.47e-06274228739879
Pubmed

MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.

MTDH EPHA7

4.47e-06274221964981
Pubmed

Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.

MRC1 MRC2

4.47e-06274217360361
Pubmed

HIV-1 Tat represses transcription from the mannose receptor promoter.

MRC1 MRC2

4.47e-06274211120831
Pubmed

The mannose receptor on murine liver sinusoidal endothelial cells is the main denatured collagen clearance receptor.

MRC1 MRC2

4.47e-06274217518370
Pubmed

[Expression of EphA7 and MTDH and clinicopathological significance in the squamous cell cancer of the tongue].

MTDH EPHA7

4.47e-06274222246354
Pubmed

Distribution of murine mannose receptor expression from early embryogenesis through to adulthood.

MRC1 MRC2

1.34e-0537429560474
Pubmed

Inhibition of DC-SIGN-mediated trans infection of T cells by mannose-binding lectin.

LMAN1 CD209

1.34e-05374212941144
Pubmed

Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry.

CST1 CST4

1.34e-0537421898352
Pubmed

Immunofluorescence localization of cystatins in human lacrimal gland and in the exorbital lacrimal gland of the rat.

CST1 CST4

1.34e-0537421471486
Pubmed

HIV gp120 binds to mannose receptor on vaginal epithelial cells and induces production of matrix metalloproteinases.

MRC1 MRC2

1.34e-05374222132194
Pubmed

EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation.

EPHA5 EPHA7

1.34e-05374227988259
Pubmed

HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.

MRC1 MRC2

1.34e-05374215955449
Pubmed

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.

MRC1 MRC2

1.34e-05374230366943
Pubmed

Comparison of macrophage phenotype between decidua basalis and decidua parietalis by flow cytometry.

MRC1 CD209

1.34e-05374218353434
Pubmed

Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S.

CST1 CST4

1.34e-0537421778989
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MRPS31 NBAS LMAN1 DYNC2H1 PIK3R1 CLPTM1 POLRMT BOP1 PFAS NIBAN2 MTDH SDF2 EPHA7

1.39e-051487741333957083
Pubmed

Oral mucosal expression of HIV-1 receptors, co-receptors, and alpha-defensins: tableau of resistance or susceptibility to HIV infection?

MRC1 CD209

2.67e-05474216672549
Pubmed

Proteins that bind high-mannose sugars of the HIV envelope.

LMAN1 CD209

2.67e-05474215572157
Pubmed

Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T.

CST1 CST4

2.67e-05474210713450
Pubmed

Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.

CST1 CST4

2.67e-05474213679380
Pubmed

cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

EPHA5 EPHA7

2.67e-0547427898931
Pubmed

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.

MRC1 MRC2

2.67e-05474224019537
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

EPRS1 CORO1C POLRMT SNX9 ADAR MTDH

2.68e-0527474634244482
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

TGM2 WWOX LMAN1 MRC2 CORO1C CLPTM1 CST4 BOP1 PFAS NIBAN2 ADAR GSN

2.98e-051367741232687490
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

TGM2 LMAN1 CST1 CST4 COL5A3

3.71e-0517574528071719
Pubmed

Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.

CST1 CST4

4.45e-05574234440840
Pubmed

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development.

CST1 CST4

4.45e-05574221443774
Pubmed

Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis.

CST1 CST4

4.45e-05574227079462
Pubmed

SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors.

MRC1 CD209

4.45e-05574232766577
Pubmed

Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation.

CST1 CST4

4.45e-05574220489058
Pubmed

Neuroprotection mediated by cystatin C-loaded extracellular vesicles.

CST1 CST4

4.45e-05574231367000
Pubmed

Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution.

CST1 CST4

4.45e-0557428761177
Pubmed

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid Beta Peptide.

CST1 CST4

4.45e-05574214742906
Pubmed

Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma.

EPHA5 EPHA7

4.45e-05574219949912
Pubmed

Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.

CST1 CST4

4.45e-05574233754041
Pubmed

Carminerin contributes to chondrocyte calcification during endochondral ossification.

CST1 CST4

4.45e-05574216680148
Pubmed

Evolution of C, D and S-type cystatins in mammals: an extensive gene duplication in primates.

CST1 CST4

4.45e-05574225329717
Pubmed

Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice.

CST1 CST4

4.45e-05574220472891
Pubmed

Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells.

CST1 CST4

4.45e-05574223671283
Pubmed

Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation.

CST1 CST4

4.45e-05574217592728
Pubmed

Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.

CST1 CST4

4.45e-05574232616516
Pubmed

Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells.

CST1 CST4

4.45e-0557422241983
Pubmed

Strong conservation of the expression of cystatin C gene in choroid plexus.

CST1 CST4

4.45e-0557421636787
Pubmed

Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse.

CST1 CST4

4.45e-05574215450354
Pubmed

Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene.

CST1 CST4

4.45e-05574210748866
Pubmed

Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice.

CST1 CST4

4.45e-05574215823274
Pubmed

Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice.

CST1 CST4

4.45e-05574221085595
Pubmed

Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation.

CST1 CST4

4.45e-05574234914637
Pubmed

A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells.

CST1 CST4

4.45e-05574216595632
Pubmed

Up-regulation of cystatin C expression in the murine hippocampus following perforant path transections.

CST1 CST4

4.45e-05574212044447
Pubmed

FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor.

CST1 CST4

4.45e-05574211144350
Pubmed

Cystatin C triggers neuronal degeneration in a model of multiple system atrophy.

CST1 CST4

4.45e-05574224405769
Pubmed

Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin.

TGM2 ITGA3

4.45e-05574210684262
Pubmed

Cystatin C is released in association with exosomes: a new tool of neuronal communication which is unbalanced in Alzheimer's disease.

CST1 CST4

4.45e-05574219773092
Pubmed

Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.

CST1 CST4

4.45e-05574224570004
Pubmed

Loss of cystatin C regulates permeability and inflammatory pathways in retina.

CST1 CST4

4.45e-05574236822364
Pubmed

The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum.

MRC1 CD209

4.45e-05574223684988
Pubmed

Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice.

CST1 CST4

4.45e-05574232467129
Pubmed

Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse.

CST1 CST4

4.45e-05574216242633
Pubmed

Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis.

CST1 CST4

4.45e-05574233027652
Pubmed

pH-dependent and dynamic interactions of cystatin C with heparan sulfate.

CST1 CST4

4.45e-05574233580179
Pubmed

Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.

TGM2 ITGA3

4.45e-05574211278623
Pubmed

CST3 alleviates retinal vascular leakage by regulating the Rap1 signaling pathway.

CST1 CST4

4.45e-05574239147193
Pubmed

Prognosis of young ischemic stroke in Taiwan: impact of prothrombotic genetic polymorphisms.

MTHFR ITGA3

4.45e-05574215351855
Pubmed

Fertility defects in mice expressing the L68Q variant of human cystatin C: a role for amyloid in male infertility.

CST1 CST4

4.45e-05574224500719
Pubmed

Control and expression of cystatin C by mouse decidual cultures.

CST1 CST4

4.45e-05574211803549
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

LMAN1 MTHFR CORO1C CST1 CST4 SNX9

4.78e-0530474632235678
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MRPS31 GPRASP1 DYNC2H1 CORO1C BOP1 PFAS NIBAN2 MTDH HIF1AN SDF2

5.23e-051005741019615732
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

EPRS1 TGM2 SEMA4B LMAN1 CELSR2 MRC2 CLPTM1 CST1 CST4 ADAR MTDH SDF2

5.31e-051451741230550785
Pubmed

Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes.

EPHA5 EPHA7

6.66e-05674212895420
Pubmed

Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy.

CST1 CST4

6.66e-05674220889561
Pubmed

Cystatin C attenuates insulin signaling transduction by promoting endoplasmic reticulum stress in hepatocytes.

CST1 CST4

6.66e-05674226592151
Pubmed

Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.

EPHA5 EPHA7

6.66e-05674215996548
Pubmed

Lack of the cysteine protease inhibitor cystatin C promotes atherosclerosis in apolipoprotein E-deficient mice.

CST1 CST4

6.66e-05674216051881
Pubmed

The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation.

CST1 CST4

6.66e-05674214607896
Pubmed

Vaginal epithelial cell-derived S100 alarmins induced by Candida albicans via pattern recognition receptor interactions are sufficient but not necessary for the acute neutrophil response during experimental vaginal candidiasis.

MRC1 CD209

6.66e-05674224478092
Pubmed

Epithelial cell-derived cytokines CST3 and GDF15 as potential therapeutics for pulmonary fibrosis.

CST1 CST4

6.66e-05674229724997
Pubmed

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity.

CST1 CST4

6.66e-05674225356866
Pubmed

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

CST1 CST4

6.66e-05674216365041
Pubmed

The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication.

PIK3R1 ADAR

6.66e-05674223853584
Pubmed

Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland.

CST1 CST4

6.66e-05674211879580
Pubmed

Cystatin C modulates cerebral beta-amyloidosis.

CST1 CST4

6.66e-05674218026102
Pubmed

CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets.

MRC1 MRC2

6.66e-05674233543002
Pubmed

Megalin-mediated endocytosis of cystatin C in proximal tubule cells.

CST1 CST4

6.66e-05674217462596
Pubmed

Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.

CST1 CST4

6.66e-05674220352108
Pubmed

HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription.

MRC1 MRC2

6.66e-05674216615932
Pubmed

Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice.

CST1 CST4

6.66e-05674215653570
Pubmed

Macrophage responses to interferon-gamma are dependent on cystatin C levels.

CST1 CST4

6.66e-05674219446036
Pubmed

Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy.

CST1 CST4

6.66e-05674211472890
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

EPRS1 ERCC6 CORO1C POLRMT BOP1 NIBAN2 ADAR MTDH GSN

7.76e-0584774935850772
CytobandEnsembl 112 genes in cytogenetic band chr12q24

B3GNT4 FBXW8 TRAFD1 CORO1C MORN3

5.69e-04415745chr12q24
Cytoband20p11.21

CST1 CST4

1.31e-033374220p11.21
GeneFamilyC-type lectin domain family

MRC1 MRC2 CD209

2.46e-0447473494
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA5 EPHA7

5.90e-04144721095
GeneFamilyCystatins, type 2

CST1 CST4

7.75e-0416472965
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNTL6 GALNT10

1.22e-0320472433
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

MRC1 CD209

2.23e-03274721253
CoexpressionLIU_PROSTATE_CANCER_DN

CLIP4 GPRASP1 GALNT10 CELSR2 MRC2 PIK3R1 CORO1C ADGRA2 EPHA7

9.15e-06493739M19391
CoexpressionKARLSSON_TGFB1_TARGETS_DN

TGM2 PIK3R1 CST1 CST4 PKHD1L1 GSN

2.61e-05209736MM1058
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_B_CELL_AGEING

TGM2 CST1 CST4 ANTKMT KDM6B

3.43e-05132735MM3822
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_CD8_POSITIVE_ALPHA_BETA_T_CELL_AGEING

CST1 CST4 KDM6B

4.02e-0524733MM3779
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_CD4_POSITIVE_ALPHA_BETA_T_CELL_AGEING

CST1 CST4 KDM6B GSN

4.94e-0572734MM3778
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

MRC1 TGM2 CORO1C NIBAN2 CD209 GSN

3.72e-071687468ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

CORO1C GPR137B SNX9 ITPKB EPHA5 CA8

5.76e-071817469d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

DYNC2H1 MRC2 ACSM1 COL5A3 ABTB2 GSN

8.13e-07192746356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

DYNC2H1 MRC2 ACSM1 COL5A3 ABTB2 GSN

8.38e-07193746dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

GALNT10 WWOX MRC2 ACSM1 ABTB2 GSN

8.64e-07194746234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

WWOX DYNC2H1 MRC2 ACSM1 ABTB2 GSN

8.90e-07195746ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

MRC2 OLFML2B COL5A3 ADGRA2 CD209

8.95e-06168745aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

MRC2 ACSM1 COL5A3 ABTB2 GSN

9.21e-061697456373562ab3b1765060212a6a53d6543e7e942e80
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 OLFML2B UNC13C PKHD1L1 RAB44

1.25e-051807453d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 OLFML2B UNC13C PKHD1L1 RAB44

1.25e-0518074547e345359064dc8ceec982b062e47802e728b43f
ToppCell3'_v3-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

GALNTL6 SEMA4B P2RX5 PKHD1L1 PRDM2

1.25e-05180745237a2130a3f48595dad2417539c21e44585962b8
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP4 P2RX5 PIH1D2 EPHA7 CA8

1.32e-05182745cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP4 P2RX5 PIH1D2 EPHA7 CA8

1.32e-05182745d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ZNF618 OLFML2B GSN BID

1.32e-051827459a68d3bd1cc9139de9e9e711c249d47ade826bb1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ZNF618 OLFML2B GSN BID

1.32e-05182745d57d18732aa6fb7b2d430601568f9ba525ac6e3c
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP4 P2RX5 PIH1D2 EPHA7 CA8

1.32e-051827457e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ZNF618 OLFML2B GSN BID

1.32e-05182745c3fb1460160744144aa31afc76c0a4d42ebdeb91
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 UNC13C PKHD1L1 EPHA5 EPHA7

1.39e-051847452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 UNC13C PKHD1L1 EPHA5 EPHA7

1.39e-05184745ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 UNC13C PKHD1L1 EPHA5 EPHA7

1.39e-051847452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Heart-LA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 ADGRA2 PKHD1L1 EPHA5 CA8

1.43e-051857451ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCellfacs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 ADGRA2 PKHD1L1 EPHA5 CA8

1.43e-05185745b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 KBTBD12 SNX9 CD209 CA8

1.43e-051857458207f9eff113eed429e961748c6b17d672a13b33
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MRC1 OLFML2B CD209 GSN CA8

1.46e-051867459673367cb53bafb873a01ef6bda11d9f392ce648
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

GALNT10 MRC2 ACSM1 ABTB2 GSN

1.50e-051877454ea486991f66c29728d127171a07b81404ec0b78
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 UNC13C ITGA3 SNX9 ABTB2

1.50e-05187745f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_DC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MRC1 OLFML2B GPR137B CD209 GSN

1.54e-0518874508eb1e4b719af53c52895557523d0a1b7421d849
ToppCellwk_08-11-Epithelial-PNS-intermediate_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

OLFML2B GPR137B COL5A3 GSN EPHA5

1.54e-051887453f3a744b2615bf72f6119f26087099110c0d21fc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 UNC13C ITGA3 SNX9 ABTB2

1.58e-05189745e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

WWOX UNC13C ABTB2 ITPKB CA8

1.62e-05190745f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 OLFML2B ADGRA2 GSN EPHA7

1.66e-051917459214655dca96d766737c9f30b624d7fe7050342e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 MRC2 PIK3R1 ADGRA2 CA8

1.66e-05191745806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

DYNC2H1 MRC2 ACSM1 COL5A3 GSN

1.66e-0519174570c067c54084bfb02c29bab085f4defd477194fb
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA6 ADGRA2 PKHD1L1 EPHA7 CA8

1.70e-0519274514a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA6 ADGRA2 PKHD1L1 EPHA7 CA8

1.70e-05192745847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SEMA4B P2RX5 GPR137B PRDM2 CA8

1.79e-05194745b8f05efb16fbed7317019efc3da7f97f81e90972
ToppCellfacs-Kidney-nan-18m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 OLFML2B ZNF316 COL5A3 GSN

1.79e-05194745bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCellfacs-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 OLFML2B ZNF316 COL5A3 GSN

1.79e-05194745fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell356C-Myeloid-Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 TGM2 CORO1C GPR137B GSN

1.79e-051947453844e6fb43ae2e0a35ea8ccc1a2e11f40b68bc67
ToppCellILEUM-inflamed-(3)_mature_DC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IDO2 TRAFD1 MTHFR GPR137B GSN

1.79e-05194745369bbf4e8e2d674e5a51a614b52b97d05d3ab9c7
ToppCellfacs-Kidney-nan-18m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 OLFML2B ZNF316 COL5A3 GSN

1.79e-051947456afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

GALNT10 MRC2 ACSM1 ABTB2 GSN

1.84e-05195745a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM2 CST1 CST4 STRA6 GSN

1.88e-05196745020110cd79453df9546fb20802fe38ecadd9fe74
ToppCellBAL-Control-cDC_5|Control / Compartment, Disease Groups and Clusters

BANP GPR137B KDM6B SNX9 BID

1.93e-051977458a3fe59be3ed1f0254cc8c60b99c840193370efb
ToppCell356C-Myeloid-Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MRC1 TGM2 CORO1C GPR137B GSN

1.93e-05197745896242e1651435bbc5b6521417e1aca36c215acd
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MRC1 TGM2 LMAN1 CORO1C GSN

1.98e-051987453b4611c9ee4d42e042a29ddb4580a95938d87d65
ToppCellMS-IIF-Lymphocyte-B-B_intermediate|IIF / Disease, condition lineage and cell class

GALNTL6 SEMA4B P2RX5 PKHD1L1 PRDM2

1.98e-05198745d6b533c5e1d55e13b1e87ce3dbacb1564bcdcc64
ToppCellmild-B_memory|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TGM2 SEMA4B P2RX5 PKHD1L1 PRDM2

2.02e-05199745e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCellsevere-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GALNTL6 SEMA4B P2RX5 SNX9 PRDM2

2.02e-0519974517283d75a2a900369f63ed02996e7ede97f46140
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

TGM2 MRC2 ITGA3 ABTB2 GSN

2.02e-05199745448ba982be804007f991d469eca9d885b21ae499
ToppCellCOVID-19-Mast_cells-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

PFAS UNC13C CD209 RNF215

9.99e-051457445c5fed4620c4c312d1052b8acad910453f7e8fcc
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

MRC1 CELSR2 KDM6B CD209

1.23e-041537445424494ea1f09542799045a875cc3eac13de5079
ToppCell(03)_Secretory-(2)_48hpi|(03)_Secretory / shred by cell type and Timepoint

EPRS1 TGM2 CORO1C GSN

1.29e-04155744d3b3d5764dfccaa4564f6063da7e13633a4f4b73
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GALNTL6 SEMA4B P2RX5 CA8

1.32e-04156744d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 ZNF618 BANP RAB44

1.36e-04157744d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellCOVID-naiveBc-|COVID / Condition, Cell_class and T cell subcluster

GALNTL6 SEMA4B P2RX5 PKHD1L1

1.43e-041597444e6783b0f69c0c70150f9f3594881dc1bac7038a
ToppCellCOVID-naiveBc|COVID / Condition, Cell_class and T cell subcluster

GALNTL6 SEMA4B P2RX5 PKHD1L1

1.43e-0415974452cd36b4412f69a935b3f76da96c166a9481eb0c
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CELSR2 MRC2 OLFML2B KDM6B

1.43e-041597442f6c60ddff2208a68146f9786143d9aefd528840
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CELSR2 MRC2 OLFML2B KDM6B

1.43e-04159744ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PIK3R1 XRN1 ZBED10P MORN3

1.53e-0416274419395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

CLIP4 MRC1 GPR137B ABTB2

1.53e-041627442f19539c455d1e5d514725845234c7547020e6ad
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|343B / Donor, Lineage, Cell class and subclass (all cells)

MRC1 CORO1C KDM6B CD209

1.53e-041627440acb8f7b51bf422d4f4f8e99bd10360163ae4eb7
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MRC1 CD209 GSN CA8

1.57e-041637444b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellCF-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

MRC1 LMAN1 CST1 ANTKMT

1.64e-0416574469ad83f2e4da62acfdf0a5a299d8444932a61160
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

GALNTL6 SEMA4B P2RX5 PRDM2

1.68e-041667448de8f388f24436b84e19ef460476fdbda4d16abf
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

GPR137B RAB44 GSN BID

1.68e-041667449f14e3ef19d5903278c040be1c477501237173fa
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 GAREM2 UNC13C PKHD1L1

1.72e-041677447abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 GAREM2 UNC13C PKHD1L1

1.72e-04167744d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IDO2 TRAFD1 GPR137B STRA6

1.72e-041677448b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSM1 UNC13C KDM6B TTLL13

1.72e-04167744a90f905ef38437752e2b0b71bd0322a184de1861
ToppCellILEUM-non-inflamed-(3)_mature_DC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IDO2 TRAFD1 GPR137B GSN

1.84e-0417074460151394460e6f27a42fab434e8b7b2adc78b128
ToppCell3'_v3-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

GALNTL6 P2RX5 PKHD1L1 PRDM2

1.88e-041717449ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFAS KDM6B SNX9 POLR3C

1.88e-04171744c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GALNTL6 P2RX5 GPR137B PRDM2

1.88e-04171744a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

IDO2 MRC2 RAB44 GSN

1.93e-04172744200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B TRAFD1 ZNF316 BID

1.97e-041737443c51e7bda1835c25915e50c801b0d643979971a3
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

IDO2 TRAFD1 CST4 GPR137B

1.97e-0417374494f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CST1 CST4 STRA6 GSN

1.97e-04173744e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B TRAFD1 ZNF316 BID

1.97e-04173744a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CELSR2 ZNF618 ZNF316

2.10e-041767445e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 TGM2 ADGRA2 PKHD1L1

2.15e-04177744227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts|Liver / Manually curated celltypes from each tissue

LMAN1 UNC13C PKHD1L1 CA8

2.15e-041777441d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 TGM2 ADGRA2 PKHD1L1

2.15e-0417774466ffa279147961080c104242a08b176e301d80e3
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

MRC1 DYNC2H1 MTHFR CORO1C

2.15e-0417774452c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

GALNTL6 SEMA4B P2RX5 CA8

2.15e-0417774468e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 TGM2 ADGRA2 PKHD1L1

2.15e-041777440cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellwk_20-22-Hematologic-Myeloid-aDC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IDO2 TRAFD1 GPR137B GSN

2.20e-04178744fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 GAREM2 UNC13C PKHD1L1

2.20e-04178744bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 GAREM2 UNC13C PKHD1L1

2.20e-04178744c413861148129be1ee94f2ceb5999840217eebe5
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 P2RX5 EPHA7 CA8

2.24e-04179744ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GALNTL6 P2RX5 KDM6B SNX9

2.24e-04179744a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 P2RX5 EPHA7 CA8

2.24e-04179744c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 CORO1C GPR137B GSN

2.29e-04180744b94618c1c2592ecf7da3535294aee9243755247a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6 GPR137B PFAS RAB44

2.34e-04181744e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

UNC13C STRA6 KDM6B GSN

2.34e-04181744f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6 GPR137B PFAS RAB44

2.34e-04181744d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCellwk_20-22-Hematologic-Myeloid-aDC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IDO2 GPR137B GSN BID

2.34e-041817448f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCell3'_v3-bone_marrow-Myeloid_Mac|bone_marrow / Manually curated celltypes from each tissue

MRC1 OLFML2B CORO1C GSN

2.39e-04182744e1d6b5de5bd1d11e968da3a55e5326ef252f55ba
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 TGM2 KDM6B PKHD1L1

2.39e-04182744fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 OLFML2B COL5A3 ADGRA2

2.39e-04182744b7d532feb73167e05475855061b35a209583f44c
DiseaseHereditary Diffuse Gastric Cancer

NBAS WWOX MTHFR CST1 BOP1 BID

7.01e-05293706C1708349
DiseaseStomach Neoplasms

NBAS WWOX MTHFR CST1 BOP1 BID

7.55e-05297706C0038356
DiseaseMalignant neoplasm of stomach

NBAS WWOX MTHFR CST1 BOP1 BID

7.98e-05300706C0024623
Diseasecatalase measurement

CELSR2 ABTB2

1.16e-047702EFO_0008071
Diseasecystatin-SA measurement

CST1 CST4

1.54e-048702EFO_0008105
Diseasecystatin-SN measurement

CST1 CST4

1.98e-049702EFO_0008106
DiseaseMicrophthalmos

ERCC6 STRA6

3.01e-0411702C0026010
DiseaseCD209 antigen measurement

CELSR2 CD209

4.96e-0414702EFO_0008077
Diseasecystatin-D measurement

CST1 CST4

7.37e-0417702EFO_0008103
Diseasesquamous cell carcinoma (is_implicated_in)

WWOX MTHFR

8.28e-0418702DOID:1749 (is_implicated_in)
Diseasechemerin measurement

UNC13C ZBED10P

9.24e-0419702EFO_0004573
DiseaseMalignant neoplasm of breast

TGM2 ERCC6 WWOX DYNC2H1 MTHFR CST4 ADAR MTDH GSN

9.61e-041074709C0006142
Diseasesquamous cell lung carcinoma, family history of lung cancer

GALNTL6 NBAS WWOX

1.10e-0385703EFO_0000708, EFO_0006953
DiseaseMammary Carcinoma, Human

TGM2 WWOX DYNC2H1 MTHFR ADAR MTDH

1.54e-03525706C4704874
DiseaseMammary Neoplasms, Human

TGM2 WWOX DYNC2H1 MTHFR ADAR MTDH

1.54e-03525706C1257931
DiseaseMammary Neoplasms

TGM2 WWOX DYNC2H1 MTHFR ADAR MTDH

1.57e-03527706C1458155
DiseaseBreast Carcinoma

TGM2 WWOX DYNC2H1 MTHFR ADAR MTDH

1.75e-03538706C0678222
Diseaseplatelet crit

TRAFD1 WWOX BANP NIBAN2 KDM6B RNF215 BID CDC7

1.84e-03952708EFO_0007985
Diseaseindole-3-propionate measurement

NBAS UNC13C

1.87e-0327702EFO_0010501
Diseasecolorectal adenocarcinoma (is_marker_for)

ERCC6 STRA6

1.87e-0327702DOID:0050861 (is_marker_for)
Diseasenecrotizing enterocolitis

IDO2 BANP

1.87e-0327702EFO_0003928
Diseaselung small cell carcinoma (is_implicated_in)

MTHFR PIK3R1

2.02e-0328702DOID:5409 (is_implicated_in)
Diseaseposterior urethral valve

FMO5 WWOX

2.16e-0329702MONDO_0019640
DiseaseNeoplasm of uncertain or unknown behavior of ovary

ERCC6 PIK3R1

2.16e-0329702C0496920
DiseaseOvarian Carcinoma

ERCC6 PIK3R1

2.31e-0330702C0029925

Protein segments in the cluster

PeptideGeneStartEntry
EDYPNGTWLGDENNP

BANP

211

Q8N9N5
YDLWAQEDPNAVLGR

BOP1

281

Q14137
WYHNRAPVEGDEQAG

ADGRA2

281

Q96PE1
NGWEEIGEVDENYAP

EPHA5

81

P54756
AGPEAALEAEEWFEG

CORO1C

366

Q9ULV4
QYWNRGEPNNVGEED

CD209

341

Q9NNX6
EEAAFPGEQGWDSLL

CELSR2

2751

Q9HCU4
EFASGQWAGIELDEP

CLIP4

306

Q8N3C7
GLPDDELEEDQFGYW

ERCC6

821

Q03468
LDRVWAYDVPEGGQA

ANTKMT

191

Q9BQD7
PDGQGWVGDVDDYSL

P4HTM

426

Q9NXG6
PGLFGDNDDWDQLLS

RAB44

361

Q7Z6P3
LAEGAPIDWGEEYSN

NIBAN2

581

Q96TA1
IGDQWEEEEGGFNYA

MTHFR

161

P42898
WDLEYLQENIGNGDF

HIF1AN

76

Q9NWT6
DPGLEIWGGEQYEIS

GALNT10

336

Q86SR1
QPGLWEQLGQLYESE

KDM6B

106

O15054
GYVWQEGEAQPAEVL

IDO2

106

Q6ZQW0
SPNEEGYWQIAAEFE

FBXW8

326

Q8N3Y1
LNNDGWQDLLVGAPY

ITGA3

316

P26006
DGLAIWYAENQGLEG

LMAN1

121

P49257
EEPLNYVGWQDGEPQ

MRC2

1201

Q9UBG0
QEARPEEIGWLNGYN

PIK3R1

46

P27986
PPNGWEEISGLDENY

EPHA7

51

Q15375
WGQNEQPGYDDLNPD

NBAS

356

A2RRP1
GFYDENLEWVGLENI

DYNC2H1

2386

Q8NCM8
YVDFENGQWATDDIP

ADAR

446

P55265
FLDGWDPAQDLLVGD

B3GNT4

231

Q9C0J1
EGHSPEDYGRQWAEN

LINC01599

61

Q8WXQ3
NLEGWNEVPDEAYDL

CDC7

531

O00311
DDIGGLWRFQENPEE

FMO5

36

P49326
YEEGVEWGLVFPDAN

CA8

31

P35219
VLAPQWEGYDELQTD

BID

46

P55957
NQPYIDDEWSGLNGL

MTDH

371

Q86UE4
QVAEGSEPDGFWEAL

GSN

631

P06396
PGGIYNADLNDEWVQ

CST1

31

P01037
PGGIYDADLNDEWVQ

CST4

31

P01036
QYWEELGAPEALREQ

POLRMT

551

O00411
DGEYWIDPNQGCARD

COL5A3

1556

P25940
IYEGQWENDKPNGEG

MORN3

136

Q6PF18
APGEELLVWYNGEDN

PRDM2

131

Q13029
LLVWYNGEDNPEIAA

PRDM2

136

Q13029
VVEIYNPDGDFWREG

KBTBD12

516

Q3ZCT8
WDVADYVIPAQGENV

P2RX5

86

Q93086
ISQLGYEPNDELWIG

MRC1

411

P22897
PENEEGAIVGSWFEA

GPRASP1

961

Q5JY77
YDSDDDLAWNIAPQG

GPR137B

346

O60478
PAGEGDQEYVSPDWA

GAREM2

401

Q75VX8
DPGLEIWGGEQYEIS

GALNTL6

331

Q49A17
WEFPINNEAGFDDDG

MRPS31

311

Q92665
PQAYQGPATGDDDDW

SNX9

151

Q9Y5X1
FVNEGLVDGWDDPRF

EPRS1

441

P07814
VAIPPNAYDESWGQD

TRAFD1

146

O14545
QPRDEDYEGAPWNCD

TAB3

676

Q8N5C8
QHDVPWQEGNREDGY

ITPKB

911

P27987
PGGEYQELLWGADAE

SEMA4B

101

Q9NPR2
AEQEAPVEGWIAVAY

RNF215

101

Q9Y6U7
ENGLWLIYPALDDEG

OLFML2B

626

Q68BL8
EGDYLDDWTVLCNGP

SDF2

126

Q99470
GSWYIDEPQGGEELQ

STRA6

21

Q9BX79
INNDAELWGVLQPYE

ABTB2

271

Q8N961
GAPRWNDYEVPEEFN

ACSM1

36

Q08AH1
PWNFLGDELYEQSDE

CLPTM1

326

O96005
DLQPGYEGWQALDPT

TGM2

346

P21980
WNLLDDLAQSDPEGY

PIH1D2

16

Q8WWB5
LPDDYIQEVIWQGEA

ZNF618

66

Q5T7W0
EPIPDDGIYWQANLD

POLR3C

226

Q9BUI4
LDNEPQGQWVGQYDS

UNC13C

726

Q8NB66
DPTLNALEIWGAEYQ

PFAS

546

O15067
YEDDIWPGENENGAE

XRN1

1011

Q8IZH2
WENETVGAQDDPLAY

ZBED10P

201

Q96FA7
AGDLPYGWEQETDEN

WWOX

56

Q9NZC7
AGSVIPQAEYEWDGN

PKHD1L1

3696

Q86WI1
PQAEYEWDGNSQVGI

PKHD1L1

3701

Q86WI1
EEENEPPGLWSAAYG

ZNF316

261

A6NFI3
YNPGELWGDIEDIII

TTLL13

326

A6NNM8