Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN3 NRXN1 NRXN2	8.90e-06	5	194	3	GO:0097109
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor-activated receptor activity	FAM72D FAM72C FAM72A FAM72B	7.43e-09	4	193	4	GO:0031551
GeneOntologyBiologicalProcess	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	3.69e-08	5	193	4	GO:0031549
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	2.54e-07	7	193	4	GO:0031548
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	6.91e-06	14	193	4	GO:0031547
GeneOntologyBiologicalProcess	microtubule-based movement	ADCY10 CLUAP1 MAP2 CFAP65 TRIM46 CFAP47 DNAH3 DNAH10 APOB DNAI3 KIFC2 ACTR3 CELSR2 DNAI7 HYDIN	6.59e-05	493	193	15	GO:0007018
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH10 DNAI3 DNAI7	1.54e-06	10	197	4	GO:0036156
GeneOntologyCellularComponent	axonemal dynein complex	DNAH3 DNAH10 DNAI3 DNAI7	8.29e-05	25	197	4	GO:0005858
GeneOntologyCellularComponent	axon initial segment	MAP2 KCNA2 TRIM46 BIN1	1.51e-04	29	197	4	GO:0043194
MousePheno	abnormal somatic hypermutation frequency	FAM72D FAM72C REV3L FAM72A FAM72B	1.61e-06	19	155	5	MP:0004815
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	1.15e-08	4	195	4	IPR026768
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	1.15e-08	4	195	4	PF14976
Domain	PP2A_PR55_CS	PPP2R2A PPP2R2B PPP2R2C	4.45e-06	4	195	3	IPR018067
Domain	PP2A_PR55	PPP2R2A PPP2R2B PPP2R2C	4.45e-06	4	195	3	IPR000009
Domain	PR55_2	PPP2R2A PPP2R2B PPP2R2C	4.45e-06	4	195	3	PS01025
Domain	PR55_1	PPP2R2A PPP2R2B PPP2R2C	4.45e-06	4	195	3	PS01024
Domain	Cadherin	CDHR3 CDHR5 PCDH12 FREM1 PCDH19 PCDHGA10 CELSR1 CELSR2	3.36e-05	118	195	8	IPR002126
Domain	Syndecan	NRXN3 NRXN1 NRXN2	3.80e-05	7	195	3	PF01034
Domain	Syndecan/Neurexin_dom	NRXN3 NRXN1 NRXN2	3.80e-05	7	195	3	IPR027789
Domain	LAM_G_DOMAIN	NRXN3 NRXN1 NRXN2 CELSR1 CELSR2	4.47e-05	38	195	5	PS50025
Domain	Laminin_G_2	NRXN3 NRXN1 NRXN2 CELSR1 CELSR2	5.76e-05	40	195	5	PF02210
Domain	LamG	NRXN3 NRXN1 NRXN2 CELSR1 CELSR2	9.20e-05	44	195	5	SM00282
Domain	CADHERIN_1	CDHR3 CDHR5 PCDH12 PCDH19 PCDHGA10 CELSR1 CELSR2	1.84e-04	113	195	7	PS00232
Domain	CADHERIN_2	CDHR3 CDHR5 PCDH12 PCDH19 PCDHGA10 CELSR1 CELSR2	1.95e-04	114	195	7	PS50268
Domain	-	CDHR3 CDHR5 PCDH12 PCDH19 PCDHGA10 CELSR1 CELSR2	1.95e-04	114	195	7	2.60.40.60
Domain	CA	CDHR3 CDHR5 PCDH12 PCDH19 PCDHGA10 CELSR1 CELSR2	2.06e-04	115	195	7	SM00112
Domain	Cadherin-like	CDHR3 CDHR5 PCDH12 PCDH19 PCDHGA10 CELSR1 CELSR2	2.17e-04	116	195	7	IPR015919
Domain	MOLYBDOPTERIN_EUK	SUOX AOX1	3.23e-04	3	195	2	PS00559
Domain	OxRdtase_Mopterin-bd_dom	SUOX AOX1	3.23e-04	3	195	2	IPR000572
Domain	OxRdtase_Mopterin_BS	SUOX AOX1	3.23e-04	3	195	2	IPR022407
Domain	Laminin_G	NRXN3 NRXN1 NRXN2 CELSR1 CELSR2	3.45e-04	58	195	5	IPR001791
Domain	Neurexin-like	NRXN3 NRXN1 NRXN2	3.75e-04	14	195	3	IPR003585
Domain	4.1m	NRXN3 NRXN1 NRXN2	3.75e-04	14	195	3	SM00294
Domain	ConA-like_dom	CMYA5 NRP1 NRXN3 NRXN1 NRXN2 TRIM46 SPSB1 CELSR1 CELSR2	5.05e-04	219	195	9	IPR013320
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ERCC6 MAP2 HSPH1 DYSF MAP3K4 KMT2C PIK3C2B C4A C4B MPP1 RASGRF2 ACAD9 PRPF8 VPS13D IKBKE WDR12 DNAI7 HYDIN	8.41e-10	497	201	18	36774506
Pubmed	Fam72a enforces error-prone DNA repair during antibody diversification.	FAM72D FAM72C FAM72A FAM72B	1.08e-09	4	201	4	34819671
Pubmed	Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.	FAM72D FAM72C FAM72A FAM72B	5.39e-09	5	201	4	19755123
Pubmed	All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.	FAM72D FAM72C FAM72A FAM72B	5.39e-09	5	201	4	26206078
Pubmed	FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.	FAM72D FAM72C FAM72A FAM72B	1.61e-08	6	201	4	34819670
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATRX RRP1B SF3A1 HSPH1 CMYA5 GTF3C5 GTF3C3 NDUFS8 NUP205 GCLC PIM1 NUP210 ITM2B DNAH10 ACAD9 IARS1 SMC6 DUOX2 APOB DDX55 PRPF8 ACTR3 PPP2R2A METTL13 THADA WDR12 PRKCI	6.43e-08	1425	201	27	30948266
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KDM3B KMT2C ALMS1 NRXN1 NRXN2 DAGLA DOP1B PRUNE2 METTL13 STK38L OGA	9.10e-08	225	201	11	12168954
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ATRX RRP1B ACADVL MAP2 SF3A1 HSPH1 WASHC2A TRIP4 GTF3C3 NDUFS8 NUP210 ITM2B PML FKBP10 STIM2 VEZT ACAD9 EPB41L5 TRAPPC8 PRPF8 LIFR THADA PRCC ANO6 WDR12 PRKCI OGA	1.51e-07	1487	201	27	33957083
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	38891114
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	16406382
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	31005376
Pubmed	Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	26446217
Pubmed	Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	11944992
Pubmed	Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	33058888
Pubmed	Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	17035546
Pubmed	Neurexins: three genes and 1001 products.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	9448462
Pubmed	Deletion of α-neurexin II results in autism-related behaviors in mice.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	25423136
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	34133920
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	30858964
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	28013231
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	31812984
Pubmed	Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	12036300
Pubmed	β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	26213384
Pubmed	Neurexin gene family variants as risk factors for autism spectrum disorder.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	29045040
Pubmed	Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	38571813
Pubmed	Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	35173587
Pubmed	Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.	PPP2R2A PPP2R2B PPP2R2C	1.90e-07	3	201	3	9514514
Pubmed	Neurexins are differentially expressed in the embryonic nervous system of mice.	NRXN3 NRXN1 NRXN2	1.90e-07	3	201	3	7722633
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HSPH1 BACE1 CEP170 ALMS1 TULP4 NUP210 MGA PRUNE2 EHBP1 STIM2 EPB41L5 TRAPPC8 VPS13D METTL13 THADA	2.16e-07	493	201	15	15368895
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RRP1B KDM3B KDM6B GRAMD4 NUP205 KMT2C ATG4B NRXN3 NRXN2 HECW2 DAGLA DDX55 CLOCK PPP2R2A OGA	5.26e-07	529	201	15	14621295
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	AXL HSPH1 LMBRD2 GTF3C3 NRP1 NEU1 MIA2 TMEM259 NUP210 C4A TIMELESS ITM2B FKBP10 STIM2 ANPEP DDX55 LIFR PPP2R2A CELSR1 THADA CELSR2 ANO6 ADPGK	5.49e-07	1201	201	23	35696571
Pubmed	Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	32706374
Pubmed	CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	8786425
Pubmed	Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	17347997
Pubmed	Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	35385735
Pubmed	Neurexins regulate presynaptic GABAB-receptors at central synapses.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	33888718
Pubmed	Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	14983056
Pubmed	Neurexins cluster Ca2+ channels within the presynaptic active zone.	NRXN3 NRXN1 NRXN2	7.57e-07	4	201	3	32134527
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	FAM72D FAM72C FAM72A FAM72B	1.41e-06	15	201	4	1741163
Pubmed	Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.	NRXN3 NRXN1 NRXN2	1.89e-06	5	201	3	36709330
Pubmed	Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.	NRXN3 NRXN1 NRXN2	1.89e-06	5	201	3	20537373
Pubmed	Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.	PPP2R2A PPP2R2B PPP2R2C	1.89e-06	5	201	3	15578586
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NRXN3 NRXN1 NRXN2	1.89e-06	5	201	3	18923512
Pubmed	Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.	NRXN3 NRXN1 NRXN2	1.89e-06	5	201	3	9223334
Pubmed	Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.	NRXN3 NRXN1 NRXN2	1.89e-06	5	201	3	28472659
Pubmed	Genetic variation and neuroimaging measures in Alzheimer disease.	CNTN5 BIN1 CR1	1.89e-06	5	201	3	20558387
Pubmed	Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.	NRXN3 NRXN1 NRXN2	3.76e-06	6	201	3	30683685
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	NRXN3 NRXN1 NRXN2	3.76e-06	6	201	3	12827191
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NRXN3 NRXN1 NRXN2	3.76e-06	6	201	3	8576240
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PIK3C2B PIK3C2G PRKCH PRKCI	6.00e-06	21	201	4	9446795
Pubmed	HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.	PPP2R2A PPP2R2B PPP2R2C	6.54e-06	7	201	3	25816751
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PIK3C2B PIK3C2G PRKCH PRKCI	7.30e-06	22	201	4	11154208
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CLUAP1 ATRX RRP1B SF3A1 BAD GTF3C5 NUP205 CEP170 NRXN1 ZNF638 EHBP1 ACAD9 IARS1 SMC6 PRPF8 CLOCK ACTR3 PPP2R2A THADA GPBP1L1 PRCC PRKCI	9.20e-06	1321	201	22	27173435
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	NRXN3 NRXN1 NRXN2	1.04e-05	8	201	3	37591863
Pubmed	The role of Vpr in HIV-1 pathogenesis.	PPP2R2A PPP2R2B PPP2R2C	1.04e-05	8	201	3	15638722
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NRXN3 NRXN1 NRXN2	1.04e-05	8	201	3	30871858
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	C4A C4B CR1	1.04e-05	8	201	3	14670299
Pubmed	Linkage map of mouse chromosome 17: localization of 27 new DNA markers.	MAP3K4 PIM1 C4A C4B	1.05e-05	24	201	4	2574145
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP2 INPPL1 BAD KDM3B CEP170 ALMS1 PIK3C2B ZNF598 PML DOP1B EHBP1 STIM2 NTRK3 EPB41L5 VPS13D IKBKE PRKCI	1.21e-05	861	201	17	36931259
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	PIK3C2B PIK3C2G PRKCH PRKCI	1.25e-05	25	201	4	15689238
Pubmed	Molecular self-avoidance in synaptic neurexin complexes.	NRXN3 NRXN1 NRXN2	1.56e-05	9	201	3	34919427
Pubmed	Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.	PPP2R2A PPP2R2B PPP2R2C	1.56e-05	9	201	3	19762425
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	NRXN3 NRXN1 NRXN2	1.56e-05	9	201	3	9707552
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATRX MAP2 BAD NRP1 CEP170 MALT1 KMT2C TULP4 NUP210 ZNF638 NQO2 DAGLA PRUNE2 EHBP1 VEZT SPSB1 PPP1R9A PPP2R2A PPP2R2C THADA PRKCI STK38L ERMARD	1.89e-05	1489	201	23	28611215
Pubmed	A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity.	SP100 BAD PIM1	2.21e-05	10	201	3	28620180
Pubmed	Common variants at 1p36 are associated with superior frontal gyrus volume.	STIM2 RASGRF2 NFE2L3	2.21e-05	10	201	3	25335168
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HSPH1 DYSF WASHC2A TRIP4 CEP170 ZNF598 MGA MPP1 IARS1 SMC6 EPB41L5 DDX55 PRPF8 ACTR3 PPP2R2A	2.30e-05	724	201	15	36232890
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	C4A C4B CR1	3.03e-05	11	201	3	23204401
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NRXN3 NRXN1 NRXN2	3.03e-05	11	201	3	32973045
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	3.32e-05	2	201	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	3.32e-05	2	201	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	3.32e-05	2	201	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	3.32e-05	2	201	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	3.32e-05	2	201	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	3.32e-05	2	201	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	3.32e-05	2	201	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	3.32e-05	2	201	2	12207352
Pubmed	Human CD180 Transmits Signals via the PIM-1L Kinase.	PIM1 CD180	3.32e-05	2	201	2	26555723
Pubmed	Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.	NRXN3 NRXN1	3.32e-05	2	201	2	37543682
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	3.32e-05	2	201	2	27758680
Pubmed	Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.	NRXN3 NRXN1	3.32e-05	2	201	2	9430716
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	3.32e-05	2	201	2	22387014
Pubmed	Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.	PPP2R2A PPP2R2B	3.32e-05	2	201	2	24244166
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	3.32e-05	2	201	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	3.32e-05	2	201	2	23918728
Pubmed	BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.	BACE1 BIN1	3.32e-05	2	201	2	27179792
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	3.32e-05	2	201	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	3.32e-05	2	201	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	3.32e-05	2	201	2	4216347
Pubmed	Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.	NRXN1 NRXN2	3.32e-05	2	201	2	30709877
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	3.32e-05	2	201	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	3.32e-05	2	201	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	3.32e-05	2	201	2	8428773
Pubmed	The SP100 component of ND10 enhances accumulation of PML and suppresses replication and the assembly of HSV replication compartments.	SP100 PML	3.32e-05	2	201	2	28439026
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	3.32e-05	2	201	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	3.32e-05	2	201	2	21345967
Pubmed	Bi-Allelic Mutations in NUP205 and NUP210 Are Associated With Abnormal Cardiac Left-Right Patterning.	NUP205 NUP210	3.32e-05	2	201	2	31306055
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	3.32e-05	2	201	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	3.32e-05	2	201	2	2302180
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	3.32e-05	2	201	2	23292348
Interaction	FBXO22 interactions	ERCC6 MAP2 HSPH1 DYSF MAP3K4 KMT2C PIK3C2B C4A C4B MPP1 RASGRF2 ACAD9 PRPF8 VPS13D IKBKE WDR12 DNAI7 HYDIN	5.92e-06	540	196	18	int:FBXO22
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.51e-04	3	129	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.51e-04	3	129	2	1189
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R2A PPP2R2B PPP2R2C	1.52e-04	15	129	3	696
GeneFamily	Fibronectin type III domain containing	AXL CMYA5 CNTN5 IGDCC3 LIFR FNDC8	1.02e-03	160	129	6	555
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2B PIK3C2G	1.38e-03	8	129	2	831
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.76e-03	9	129	2	1234
GeneFamily	BRICHOS domain containing	ITM2B ITM2A	1.76e-03	9	129	2	457
GeneFamily	Complement system\|Sushi domain containing	C4A C4B CR1	2.13e-03	36	129	3	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B CR1	2.31e-03	37	129	3	454
GeneFamily	Acyl-CoA dehydrogenase family	ACADVL ACAD9	2.66e-03	11	129	2	974
GeneFamily	Non-clustered protocadherins	PCDH12 PCDH19	3.18e-03	12	129	2	21
Coexpression	GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP	SP100 AEBP1 PIK3C2B GUSBP11 ITM2A RUBCNL SMC6 CR1 TRBC1 OGA	2.48e-06	193	200	10	M4961
Coexpression	BUSSLINGER_DUODENAL_MATURE_ENTEROCYTES	ACADVL CDHR5 ATG4B MIA2 MPP1 AMN ANPEP APOB MIGA2 LPIN2 SLC28A1	5.32e-06	259	200	11	M40029
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN	AXL PCDH12 MS4A2 NRXN2 EHBP1 ANPEP IARS1 VPS13D GPBP1L1	1.93e-05	194	200	9	M8864
Coexpression	GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP	ADCY10 CMYA5 DYSF NRP1 ALMS1 PIM1 AOX1 APOB ERMARD	2.27e-05	198	200	9	M7200
Coexpression	GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP	MALT1 TULP4 BIN1 CLOCK OSBP VPS13D CELSR1 GPBP1L1 TRBC1	2.27e-05	198	200	9	M5591
Coexpression	GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP	CLUAP1 SF3A1 PIM1 PLCL1 ITM2B ITM2A LPIN2 PRKCH TRBC1	2.36e-05	199	200	9	M3084
Coexpression	GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN	AXL CDHR5 KDM6B CSRNP1 UBA7 TIMELESS PML MPP1 RASGEF1B	2.46e-05	200	200	9	M9839
Coexpression	GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN	TRIP4 NRP1 TULP4 SUOX BIN1 STIM2 SPSB1 STK38L ADPGK	2.46e-05	200	200	9	M5695
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR5 GRAMD4 NRP1 CNTN5 NQO2 PRUNE2 ANPEP AOX1 CELSR1 SLC28A1	1.37e-08	186	201	10	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 DDC NRP1 PRUNE2 AMN ANPEP RASGEF1B SLC28A1	1.50e-07	182	201	9	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 DDC NRP1 PRUNE2 AMN ANPEP RASGEF1B SLC28A1	1.50e-07	182	201	9	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	CDHR3 NRP1 PLCL1 PRUNE2 BIN1 ANPEP AOX1 SLC28A1 HYDIN	1.65e-07	184	201	9	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	1.73e-07	185	201	9	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CDHR3 NRP1 MALT1 MIA2 GCLC PRUNE2 ANPEP AOX1 SLC28A1	1.89e-07	187	201	9	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCDH12 DYSF NRP1 HECW2 ITM2A STIM2 PPP1R9A LIFR PRKCH	2.47e-07	193	201	9	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCDH12 DYSF NRP1 HECW2 ITM2A STIM2 PPP1R9A LIFR PRKCH	2.47e-07	193	201	9	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.58e-07	194	201	9	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	CLUAP1 CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.82e-07	196	201	9	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CLUAP1 CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.94e-07	197	201	9	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	distal-Epithelial-Ciliated-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.20e-07	199	201	9	2de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.34e-07	200	201	9	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Biopsy_Other_PF-Epithelial-Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.34e-07	200	201	9	721371698bce8890853fb6b6b01a2c20293b39e9
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYGB TMEM215 FREM1 NRP1 AEBP1 NOTUM MXRA5 CYP26B1 NTRK3	3.34e-07	200	201	9	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.34e-07	200	201	9	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HENMT1 NRXN3 AEBP1 EHBP1 CYP26B1 DNAH10 SPSB1 DGKK	6.26e-07	158	201	8	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HENMT1 NRXN3 AEBP1 EHBP1 CYP26B1 DNAH10 SPSB1 DGKK	6.26e-07	158	201	8	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYGB NRXN3 AEBP1 PIK3C2G C4B UNC79 DNAH10 HYDIN	1.24e-06	173	201	8	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYGB NRXN3 AEBP1 PIK3C2G C4B UNC79 DNAH10 HYDIN	1.24e-06	173	201	8	649b08a409095592cccf31883be69c754411280d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 AMN ANPEP AOX1 SLC28A1	1.41e-06	176	201	8	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NRP1 PRUNE2 AMN ANPEP AOX1 SLC28A1	1.60e-06	179	201	8	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	1.74e-06	181	201	8	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 AMN ANPEP AOX1 SLC28A1	1.89e-06	183	201	8	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 HECW2 CNTN5 FKBP10 DNAH10 NTRK3 AOX1 HYDIN	1.89e-06	183	201	8	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM1 NRXN1 PIK3C2G UNC79 DNAH10 APOB DGKK HYDIN	1.97e-06	184	201	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM1 NRXN1 PIK3C2G UNC79 DNAH10 APOB DGKK HYDIN	1.97e-06	184	201	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 AMN ANPEP AOX1 SLC28A1	1.97e-06	184	201	8	9434731f651820b05335085582960f08fbf895de
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM1 NRXN1 PIK3C2G UNC79 DNAH10 APOB DGKK HYDIN	1.97e-06	184	201	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN3 NRXN2 ITM2A NID2 SPSB1 DUOX2 CELSR1 FNDC8	2.05e-06	185	201	8	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN3 NRXN2 ITM2A NID2 SPSB1 DUOX2 CELSR1 FNDC8	2.05e-06	185	201	8	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 AMN ANPEP AOX1 SLC28A1	2.13e-06	186	201	8	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	CYGB NRP1 AEBP1 PCDH19 C4B ITM2A ANPEP PPP2R2B	2.13e-06	186	201	8	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.13e-06	186	201	8	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 GPR162 CNTN5 CFAP47 DNAH3 DNAH10 DNAI7 HYDIN	2.13e-06	186	201	8	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.13e-06	186	201	8	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 BIN1 AMN ANPEP SLC28A1	2.22e-06	187	201	8	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NUDT8 NRP1 NQO2 PRUNE2 ANPEP CELSR1 SLC28A1	2.22e-06	187	201	8	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 AMN ANPEP AOX1 SLC28A1	2.22e-06	187	201	8	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NRP1 MALT1 MIA2 PRUNE2 ANPEP CELSR1 SLC28A1	2.22e-06	187	201	8	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NQO2 PRUNE2 BIN1 AMN ANPEP AOX1 SLC28A1	2.22e-06	187	201	8	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NQO2 PRUNE2 BIN1 AMN ANPEP AOX1 SLC28A1	2.22e-06	187	201	8	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	CDHR3 CDHR5 NRP1 PRUNE2 ANPEP AOX1 RASGEF1B SLC28A1	2.22e-06	187	201	8	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 NQO2 PRUNE2 BIN1 AMN ANPEP SLC28A1	2.22e-06	187	201	8	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	(04)_Pre-ciliated-(3)_72hpi\|(04)_Pre-ciliated / shred by cell type and Timepoint	HSPH1 CFAP65 DNAH10 NICN1 DNAI3 VPS13D DNAI7 HYDIN	2.31e-06	188	201	8	f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 MIA2 NQO2 PRUNE2 AMN ANPEP SLC28A1	2.31e-06	188	201	8	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.31e-06	188	201	8	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.31e-06	188	201	8	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 CDHR5 MIA2 NQO2 PRUNE2 AMN ANPEP SLC28A1	2.31e-06	188	201	8	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL CYGB CMYA5 AEBP1 PCDH19 C4B NTRK3 THADA	2.40e-06	189	201	8	544d95df910f1b276995624509a7e41b219baca0
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDHR3 GPR162 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.40e-06	189	201	8	a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	CDHR3 GPR162 DNAH3 DNAH10 DNAI3 ERICH2 DNAI7 HYDIN	2.40e-06	189	201	8	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.40e-06	189	201	8	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CDHR3 NRP1 MALT1 MIA2 PRUNE2 ANPEP AOX1 SLC28A1	2.40e-06	189	201	8	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDHR3 GPR162 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.40e-06	189	201	8	93b1026bb1ba759e5704561c9a5de14a30c08894
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN3 NRXN2 ITM2A NID2 SPSB1 DUOX2 CELSR1 FNDC8	2.50e-06	190	201	8	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN3 NRXN2 ITM2A NID2 SPSB1 DUOX2 CELSR1 FNDC8	2.50e-06	190	201	8	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN3 NRXN2 ITM2A NID2 SPSB1 DUOX2 CELSR1 FNDC8	2.50e-06	190	201	8	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NRP1 PRUNE2 EHBP1 ANPEP AOX1 CELSR1 SLC28A1	2.60e-06	191	201	8	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.60e-06	191	201	8	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NRP1 PRUNE2 EHBP1 ANPEP AOX1 CELSR1 SLC28A1	2.60e-06	191	201	8	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.60e-06	191	201	8	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.60e-06	191	201	8	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	Ciliated-cil-3\|World / Class top	CDHR3 HSPH1 CFAP65 DNAH3 DNAH10 DNAI3 ERICH2 HYDIN	2.70e-06	192	201	8	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 CNTN5 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.70e-06	192	201	8	1b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	2.81e-06	193	201	8	2661ad9107ed9231e4afea4442a79051139a31df
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 CELSR1 HYDIN	2.81e-06	193	201	8	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.81e-06	193	201	8	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	2.81e-06	193	201	8	f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCell	PCW_05-06-Endothelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	2.92e-06	194	201	8	00291c62795a55a7e63b1db10c139d6a3298e55e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	2.92e-06	194	201	8	9bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLUAP1 CDHR3 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	2.92e-06	194	201	8	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	2.92e-06	194	201	8	eb279e0d922de921343f0ae032a809f837d915b3
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MAP2 NRXN3 ALMS1 SUOX ZNF598 UNC79 RAI2	3.01e-06	137	201	7	b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.03e-06	195	201	8	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.03e-06	195	201	8	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX TMEM215 DDC KMT2C NRXN1 TULP4 MGA REV3L	3.03e-06	195	201	8	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDH12 DYSF NRP1 ITM2B ITM2A MAP4K2 LIFR PRKCH	3.03e-06	195	201	8	9ad4981c4d157edc752de206ab0d754aa14beab8
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.03e-06	195	201	8	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.15e-06	196	201	8	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SP100 PCDH12 DYSF ITM2A MAP4K2 MPP1 CYP26B1 PRKCH	3.15e-06	196	201	8	85b697db1c925eff8bbef9d74565c82be5a0ddcc
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.27e-06	197	201	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.27e-06	197	201	8	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.27e-06	197	201	8	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR5 DDC NQO2 PRUNE2 BIN1 AMN ANPEP AOX1	3.39e-06	198	201	8	72733b6149b797ac11cc108bc80428b77fbbba78
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CLUAP1 CDHR3 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.39e-06	198	201	8	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR5 DDC NQO2 PRUNE2 BIN1 AMN ANPEP AOX1	3.39e-06	198	201	8	f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.52e-06	199	201	8	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI7 HYDIN	3.52e-06	199	201	8	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	ACADVL HSPH1 KDM6B CSRNP1 NEU1 NRXN2 ITM2A FKBP10	3.52e-06	199	201	8	0d1f2b0d10c1f8ee10c448659b2a22ea0a6a6f0d
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.52e-06	199	201	8	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 GPR162 CFAP65 CFAP47 DNAH3 DNAH10 DNAI7 HYDIN	3.52e-06	199	201	8	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CDHR3 GPR162 CFAP65 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.52e-06	199	201	8	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	distal-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CDHR3 GPR162 CFAP65 DNAH10 DNAI3 ERICH2 DNAI7 HYDIN	3.52e-06	199	201	8	97b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 CFAP65 CFAP47 DNAH3 DNAH10 DNAI3 DNAI7 HYDIN	3.66e-06	200	201	8	55c148238d5c80c1faa3428a917ae8075be2c145
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	PPP2R2A PPP2R2B PPP2R2C	5.37e-05	12	188	3	DOID:1441 (implicated_via_orthology)
Disease	superior frontal gyrus grey matter volume measurement	STIM2 RASGRF2 NFE2L3	8.80e-05	14	188	3	EFO_0006516
Disease	reaction time measurement	DYSF NRXN1 CNTN5 ZNF638 MMS22L STIM2 DNAH10 PPP1R9A PPP2R2A PPP2R2B CACNA2D4 TMEM87B RASGEF1B	3.28e-04	658	188	13	EFO_0008393
Disease	quality of life during menstruation measurement, Arthralgia	DOP1B CACNA2D4	3.99e-04	5	188	2	EFO_0009366, HP_0002829
Disease	adenoid cystic carcinoma (is_implicated_in)	KMT2C NTRK3	3.99e-04	5	188	2	DOID:0080202 (is_implicated_in)
Disease	Carcinoma of lung	ERCC6 MXRA5 NTRK3	4.10e-04	23	188	3	C0684249
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	EHBP1 SMC6 APOB NFE2L3 CELSR2	4.39e-04	99	188	5	EFO_0004611, EFO_0007878
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	EHBP1 SMC6 APOB NFE2L3 CELSR2	5.03e-04	102	188	5	EFO_0004329, EFO_0004611
Disease	axial length measurement, refractive error	CNTN5 RASGRF2	5.96e-04	6	188	2	EFO_0005318, MONDO_0004892
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	MAP3K4 BSND EHBP1 DNAH10 APOB NFE2L3 CELSR2	6.26e-04	225	188	7	EFO_0008317, EFO_0010351
Disease	Intellectual Disability	KDM3B PCDH12 KDM6B METTL23 GTF3C3 KMT2C KCNA2 NRXN1 NRXN2 ALG13	6.27e-04	447	188	10	C3714756
Disease	docosapentaenoic acid measurement	DAGLA STIM2 SLC10A2	6.65e-04	27	188	3	EFO_0006809
Disease	caudate volume change measurement, age at assessment	NRXN3 NRXN1 CNTN5	6.65e-04	27	188	3	EFO_0008007, EFO_0021491
Disease	lipoprotein A measurement	MAP3K4 TULP4 APOB NFE2L3 CELSR2	7.70e-04	112	188	5	EFO_0006925
Disease	LDL cholesterol change measurement	APOB CELSR2	8.30e-04	7	188	2	EFO_0007804
Disease	fructosamine measurement	CNTN5 MAP4K2	8.30e-04	7	188	2	EFO_0009303
Disease	low density lipoprotein cholesterol measurement, physical activity	EHBP1 APOB NFE2L3 CELSR2	8.45e-04	66	188	4	EFO_0003940, EFO_0004611
Disease	obstructive sleep apnea	NRP1 NRXN3 MMS22L THADA	8.45e-04	66	188	4	EFO_0003918
Disease	common carotid intimal medial thickness	ATG4B MMS22L APOB CD180	8.94e-04	67	188	4	EFO_0004860
Disease	glycocholate measurement	DYSF GCLC SLC10A2	9.10e-04	30	188	3	EFO_0010491
Disease	Major Depressive Disorder	MAP2 CMYA5 DDC ANPEP NTRK3 CLOCK IKBKE	9.82e-04	243	188	7	C1269683
Disease	Alzheimer disease, educational attainment	CEP170 MS4A2 NRXN1 PIK3C2B BIN1 CR1 OGA	1.08e-03	247	188	7	EFO_0011015, MONDO_0004975
Disease	marginal zone B-cell lymphoma	APOB PRKCH	1.10e-03	8	188	2	EFO_1000630
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	APOB CELSR2	1.10e-03	8	188	2	EFO_0008589, EFO_0008595
Disease	7-methylguanine measurement	PPP1R9A AOX1	1.10e-03	8	188	2	EFO_0021123
Disease	Mental deterioration	BIN1 CR1	1.41e-03	9	188	2	C0234985
Disease	Mild cognitive disorder	BIN1 CR1	1.41e-03	9	188	2	C1270972
Disease	Osteitis Deformans	NUP205 PML	1.41e-03	9	188	2	C0029401
Disease	Unipolar Depression	MAP2 CMYA5 DDC ANPEP NTRK3 CLOCK IKBKE	1.42e-03	259	188	7	C0041696
Disease	coronary artery disease	RRP1B NRP1 BSND NRXN1 NUP210 PLCL1 EHBP1 DNAH10 PPP1R9A DUOX2 APOB CLOCK PPP2R2A THADA CELSR2 RASGEF1B WDR12	1.72e-03	1194	188	17	EFO_0001645
Disease	2-ketocaprylate measurement	ALMS1 HEATR4	1.76e-03	10	188	2	EFO_0800110
Disease	Semantic-Pragmatic Disorder	KCNA2 NRXN1	2.14e-03	11	188	2	C0454655
Disease	Auditory Processing Disorder, Central	KCNA2 NRXN1	2.14e-03	11	188	2	C0751257
Disease	Language Delay	KCNA2 NRXN1	2.14e-03	11	188	2	C0023012
Disease	Language Development Disorders	KCNA2 NRXN1	2.14e-03	11	188	2	C0023014
Disease	Speech Delay	KCNA2 NRXN1	2.14e-03	11	188	2	C0241210
Disease	Pathological accumulation of air in tissues	PPP2R2A PPP2R2C	2.56e-03	12	188	2	C0013990
Disease	level of Ceramide (d42:2) in blood serum	GRAMD4 APOB	2.56e-03	12	188	2	OBA_2045186
Disease	obesity (implicated_via_orthology)	ALMS1 STIM2 DNAH10 THADA LPIN2 PRKCI	2.63e-03	215	188	6	DOID:9970 (implicated_via_orthology)
Disease	sleep duration, low density lipoprotein cholesterol measurement	BSND GCLC APOB CELSR2	2.77e-03	91	188	4	EFO_0004611, EFO_0005271
Disease	late-onset Alzheimers disease	DYSF PLCL1 ZNF438 BIN1 AOX1 CR1 SLC10A2	2.78e-03	292	188	7	EFO_1001870
Disease	osteitis deformans	NUP205 PML	3.01e-03	13	188	2	EFO_0004261
Disease	liver cirrhosis (implicated_via_orthology)	CYGB GCLC	3.01e-03	13	188	2	DOID:5082 (implicated_via_orthology)
Disease	disease progression measurement, Crohn's disease	CDHR3 NRP1 CNTN5	3.36e-03	47	188	3	EFO_0000384, EFO_0008336
Disease	Impaired cognition	BIN1 CR1	3.49e-03	14	188	2	C0338656
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	APOB CELSR2	3.49e-03	14	188	2	EFO_0004611, EFO_0008589
Disease	Cardiomyopathy, Dilated	CSRNP1 ALMS1 WDR12	3.57e-03	48	188	3	C0007193
Disease	total lipids in lipoprotein particles measurement	BSND APOB CELSR2	3.57e-03	48	188	3	EFO_0022309
Disease	apolipoprotein B measurement	ACADVL BACE1 BSND GPSM2 EHBP1 DNAH10 APOB NFE2L3 THADA CELSR2 HYDIN	3.66e-03	663	188	11	EFO_0004615
Disease	cholesteryl esters to total lipids in small VLDL percentage	APOB NFE2L3 CELSR2	3.78e-03	49	188	3	EFO_0022256
Disease	Adenoid Cystic Carcinoma	ATRX KDM6B KMT2C MGA	3.89e-03	100	188	4	C0010606
Disease	Pancreatic Neoplasm	ATRX AXL NRP1 RBBP8	3.89e-03	100	188	4	C0030297
Disease	Cardiomyopathy, Familial Idiopathic	CSRNP1 ALMS1 WDR12	4.00e-03	50	188	3	C1449563
Disease	Hypertriglyceridemia	APOB CELSR2	4.01e-03	15	188	2	C0020557
Disease	response to statin, LDL cholesterol change measurement	APOB CELSR2	4.01e-03	15	188	2	EFO_0007804, GO_0036273
Disease	inherited metabolic disorder (is_implicated_in)	DDC SUOX	4.01e-03	15	188	2	DOID:655 (is_implicated_in)
Disease	Alzheimer disease	CDHR3 TRIP4 NRXN3 MS4A2 PIK3C2G BIN1 CR1 FAM157C WDR12	4.08e-03	485	188	9	MONDO_0004975
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	DYSF UBA7 ZNF638 PLCL1 MMS22L NTRK3 METTL13 OGA	4.16e-03	398	188	8	EFO_0003756, EFO_0003888, EFO_0004337
Disease	Malignant neoplasm of pancreas	ATRX AXL NRP1 RBBP8	4.17e-03	102	188	4	C0346647
Disease	cholesterol to total lipids in small HDL percentage	APOB NFE2L3 CELSR2	4.23e-03	51	188	3	EFO_0022240
Disease	free cholesterol measurement, intermediate density lipoprotein measurement	BSND APOB NFE2L3 CELSR2	4.47e-03	104	188	4	EFO_0008591, EFO_0008595
Disease	response to cisplatin, platinum measurement	DYSF NRXN1 MMS22L	4.72e-03	53	188	3	EFO_0010154, GO_0072718
Disease	free cholesterol to total lipids in small LDL percentage	DCT APOB CELSR2	4.72e-03	53	188	3	EFO_0022286
Disease	cholesteryl esters to total lipids in very large VLDL percentage	APOB NFE2L3 CELSR2	4.72e-03	53	188	3	EFO_0022258
Disease	cholesterol to total lipids in very large VLDL percentage	APOB NFE2L3 CELSR2	4.97e-03	54	188	3	EFO_0022244
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOB CELSR2	5.16e-03	17	188	2	EFO_0022232
Disease	triglycerides in medium VLDL measurement	DNAH10 APOB CELSR2	5.24e-03	55	188	3	EFO_0022155
Disease	cholesterol to total lipids in large HDL percentage	APOB NFE2L3 CELSR2	5.24e-03	55	188	3	EFO_0022234
Disease	cholesteryl esters to total lipids in large VLDL percentage	APOB NFE2L3 CELSR2	5.51e-03	56	188	3	EFO_0022250
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	APOB CELSR2	5.78e-03	18	188	2	EFO_0008317, EFO_0008589

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSAPLPLENETEISE	CEP170	606	Q5SW79
EPENPEAKEFFTLIE	ERICH2	96	A1L162
PAFEVLEISPQEVSS	MS4A2	21	Q01362
EIARPDDSLEPFFDS	BACE1	186	P56817
EEPEDPSNRSFFSEI	PPP2R2B	266	Q00005
EEPEDPSNRSFFSEI	PPP2R2C	266	Q9Y2T4
DNVFVPPESLQEVDE	ADPGK	191	Q9BRR6
VVPEPFSTESFTLDV	ALG13	46	Q9NP73
EEDVIPDSPITAFSF	RBBP8	156	Q99708
DFQEPEEELPLTAIF	C2orf72	251	A6NCS6
SIFQDDFVIPDISEP	C4B	196	P0C0L5
LIDEDDIPVRSFFPE	C4B	766	P0C0L5
EPEDPSNRSFFSEII	PPP2R2A	271	P63151
MFQIPEFEPSEQEDS	BAD	1	Q92934
EPEFETQLEPEFETQ	AEBP1	1106	Q8IUX7
TQLEPEFETQLEPEF	AEBP1	1111	Q8IUX7
FRFQPEENTVETEEP	GRAMD4	181	Q6IC98
KEVFPFPEVSQDELN	ACAD9	51	Q9H845
PFEADISSLFQVEPL	GUSBP11	151	Q6P575
IFSQQTLPDFLFPEE	ALMS1	916	Q8TCU4
FRNPVFDVTASEELP	AMN	406	Q9BXJ7
FLLDPDSNVTRPSEF	ANPEP	566	P15144
LDVNDNEPIFVSSPF	CELSR1	556	Q9NYQ6
EEFPRELESSVSFPA	CELSR1	2271	Q9NYQ6
DNPPVFEQDEFDVFV	CELSR2	916	Q9HCU4
ETSAFFPENRSPEEI	ADCY10	1016	Q96PN6
FVSVLDVNDNAPEFP	CDHR5	111	Q9HBB8
EIPDTLPNTTEFLEF	CD180	46	Q99467
APQEPDTFEDIINDV	DDC	46	P20711
EESIEIPFDVPSTFL	DNAI3	541	Q8IWG1
FPESEPEVKAVANFL	CPA6	296	Q8N4T0
KVPVQEIDDDFFPSS	ERCC6	416	Q03468
LRFAEFEDFPETSEP	ATG4B	11	Q9Y4P1
LFAEEEFLPLDPTQE	AOX1	201	Q06278
FVQEPDDIIFPTDSD	CNTN5	101	O94779
EVSPPIFQEDAALDL	RAI2	331	Q9Y5P3
NSFSPEVFVLPVDVE	RUBCNL	191	Q9H714
PNSEEVDEVFALPLA	NUDT8	131	Q8WV74
SEIDENTFFVPTAPK	PIK3C2G	56	O75747
FSQEIPEPLQLDFFD	NUP205	1191	Q92621
PDAAATEEPRTFQTF	PCDH12	1076	Q9NPG4
LAPELTFDFPIETVV	MAP4K2	736	Q12851
DESIIKPEQEFFTAP	ANO6	171	Q4KMQ2
KVPVQEIDDDFFPSS	ERCC6	416	P0DP91
ARFPETPAFSSQEEE	HECW2	666	Q9P2P5
EVSQPFFIEIASPFS	OVOS1	676	Q6IE37
APSFPAAQIELEISE	PCDH19	126	Q8TAB3
DFPSQDVFTVEPQFD	NUP210	1621	Q8TEM1
FFLEDDPEDINQTSP	DGKK	801	Q5KSL6
ADERESQFPSIPDAF	KCNA2	351	P16389
FTNEPVQLTPDDDDI	PRKCI	556	P41743
SVPVVSPNTDEFLDL	GPSM2	536	P81274
EPFFPNIDFDAITDP	KMT2C	3081	Q8NEZ4
ELAFAVEPSDDVAVP	IGDCC3	41	Q8IVU1
EVEFISVPVPEFADS	ITM2B	126	Q9Y287
DNPEENSSEFPVTFK	MGA	2121	Q8IWI9
SNVPVETTDEIPFSF	MALT1	801	Q9UDY8
PESTDNFILFDEVSP	NTRK3	401	Q16288
DLFSTDIPPTNAVDF	FAM72D	41	Q6L9T8
FREEITTFIDETPLP	GPR162	501	Q16538
EPAAEALDPFIDSQF	CSRNP1	561	Q96S65
ALDPFIDSQFEDTVP	CSRNP1	566	Q96S65
KLQFEEEDFPSLNPE	GPBP1L1	151	Q9HC44
DPLPTNFEEDTLEIF	MMS22L	61	Q6ZRQ5
SAVNAPFRIEISPDE	CFAP65	386	Q6ZU64
DTAPVFKDVNVFDPD	CYP26B1	401	Q9NR63
AFIPEVDTEGPAFLS	DOP1B	2176	Q9Y3R5
VPFPFDETELQGEFT	FAM91A1	616	Q658Y4
EFSVTDAVPFPISLI	HSPH1	391	Q92598
PENAFGLPEDEFLVV	IKBKE	101	Q14164
TPLEDQFEEPAEFKI	KDM6B	676	O15054
FPDFVPVDVNTDTIP	DDX55	471	Q8NHQ9
DPSISPEFVVASEQF	DUOX2	321	Q9NRD8
LRQPAPFSDEIEVDF	PCYT1A	41	P49585
VFDANDNAPVFTLPE	PCDHGA10	236	Q9Y5H3
DNFDPIDVSQLFDEP	NFE2L3	401	Q9Y4A8
AADDLEFVLVSPPQF	FREM1	1056	Q5H8C1
KNTPSPFIETFTEDD	GCLC	211	P48506
ALDPVTFESPEAFVA	NRXN2	491	Q9P2S2
ENVATLDPINFETPE	NRXN3	441	Q9Y4C0
LVFFIDSPTVIAVPD	FAM157C	361	P0CG43
EEPSNPFLAFVEKVE	KDM3B	631	Q7LBC6
SRQIFPPESFADTEA	FAM161B	16	Q96MY7
AFEDLENPPASVLAV	MIGA2	441	Q7L4E1
LPPQDIILASDVFFE	METTL23	91	Q86XA0
DLFSTDIPPTNAVDF	FAM72A	41	Q5TYM5
VATLDPITFETPESF	NRXN1	476	Q9ULB1
FEVPQARSDPLAFIT	OVOS2	71	Q6IE36
APQISFAPEIASEEE	NQO2	186	P16083
PEEFVQAFVQKDPLD	RASGEF1B	226	Q0VAM2
ENEFFDAPEIITMPE	OSBP	356	P22059
PVDAIVEGPNFEFST	NDUFS8	161	O00217
PDSVILQIDFPTSAF	PIK3C2B	776	O00750
GQPVESFPLDFTAVE	NOTUM	46	Q6P988
TDFPAIAPFLADIDT	NID2	101	Q14112
ILEFESFDLEPDSNP	NRP1	186	O14786
SQPEDSLIPFFEITV	APOB	3801	P04114
EFANPDFTQPISEVV	ACTR3	286	P61158
DIVSVPSSVPEDIFE	ATRX	516	P46100
PSSVPEDIFENLETA	ATRX	521	P46100
PELVSEFRFVPIQTE	EPB41L5	181	Q9HCM4
EVPPEEFSTFIKAQV	FKBP10	516	Q96AY3
EFNPLFPSVTLRDSD	HENMT1	166	Q5T8I9
FVFVIPPSEDISLDE	HYDIN	2636	Q4G0P3
FALIDAPTLEDEPQE	BSND	241	Q8WZ55
FARPTNLTDEFEFPI	CR1	51	P17927
IFEPADLEQASPATV	DNAH3	1831	Q8TD57
VSLETFPLDFTEPLN	GFY	76	I3L273
FEDILQPETEFVFPL	DBNDD2	121	Q9BQY9
TFFLQEPPEEEEDVL	FAM163B	101	P0C2L3
PEDEASVFTLDRFPL	CACNA2D4	786	Q7Z3S7
VEAFDPEDTSRNIPL	CDHR3	156	Q6ZTQ4
LNVPVQVSFPEEEFA	CMYA5	3371	Q8N3K9
ILEVVAEEFASDFPP	CYGB	131	Q8WWM9
DLFSTDIPPTNAVDF	FAM72C	41	H0Y354
ETAEFEDQSVILPPQ	HEATR4	266	Q86WZ0
ETTEEFETENAFPPI	DNAI7	421	Q6TDU7
FETENAFPPIEVTLE	DNAI7	426	Q6TDU7
NPFDEPEAFVTIKDS	EHBP1	321	Q8NDI1
DNIAIIDVPVPSFSD	ITM2A	121	O43736
EALNDSQEFPFPETP	TMEM259	186	Q4ZIN3
DQLAQIAPETVPEDF	MALSU1	201	Q96EH3
PSPQVLEFAEFIDSL	DAGLA	906	Q9Y4D2
PFQPTLEEIEEFLEE	KLF15	136	Q9UIH9
AELSPFIVFIAPTDQ	MPP1	391	Q00013
TSFPELFPEIFDALE	ERMARD	101	Q5T6L9
VDFELEELSSVPFVN	FAM102B	11	Q5T8I3
RFEFQDVIPPDDFLT	HLTF	36	Q14527
DQVLEAEPQFSLPVF	METTL13	191	Q8N6R0
LFEDTFVPEISVTTP	BIN1	361	O00499
ISLFSVFNVPFPSEE	DNAH10	2586	Q8IVF4
EQPEAKFEFETPAFE	CFAP47	2316	Q6ZTR5
FDSPGELFDEPIFIT	DYSF	271	O75923
VFPPDASQEEVFREL	KIFC2	451	Q96AC6
SIFQDDFVIPDISEP	C4A	196	P0C0L4
LIDEDDIPVRSFFPE	C4A	766	P0C0L4
DLFSTDIPPTNAVDF	FAM72B	41	Q86X60
ELAPIVAPNFTVEDT	LIFR	721	P42702
LSFTPEELNVVFTFP	SLC10A2	276	Q12908
STLFEDQVPALEAPE	MIA2	171	Q96PC5
LVKNDRPVEFSEFPD	MAP3K4	561	Q9Y6R4
AIEPAFISALPEDDF	MAP3K4	1101	Q9Y6R4
ERPEPVQDLFDFITE	PIM1	121	P11309
ESSVVVDLPDTPFIF	FNDC8	171	Q8TC99
ESFIPVLQDTFDNPE	RTL3	306	Q8N8U3
IFPFAPSPNEEESED	RTL5	326	Q5HYW3
EDATVEASPPFAFLT	TRIM46	641	Q7Z4K8
FVPDPFFVELTESLL	THADA	431	Q6YHU6
VFEAIVDQSPFVPEE	RRP1B	216	Q14684
FDDFPESDILQPVPN	STK38L	411	Q9Y2H1
LAQDDPPIIFEASVD	TAPBPL	86	Q9BX59
LAVTFSPQTEEPEEV	PRUNE2	1386	Q8WUY3
PERVFSVEESPALEA	SH3D21	331	A4FU49
DSDEEVAPENFFSLP	PRCC	266	Q92733
VPFPFDETELQEDSC	LINC00869	261	P0C866
EPLDFNAETFTDDPL	LMBRD2	656	Q68DH5
EEQEVLPETFLANFP	OGA	826	O60502
DFKIVVEPPDAAAFT	RASGRF2	551	O14827
PTERAPASEEEFQFL	PML	41	P29590
DFDIVTETSFPIPGQ	GCM2	216	O75603
TFPSVAPFELQEITF	NICN1	36	Q9BSH3
DVTFDPELVDPVVAA	NEU1	306	Q99519
VFLRFSEEEISFPPT	INPPL1	646	O15357
PLELSEFESFPVFQD	SCP2D1	36	Q9UJQ7
VEFSAFVEPPDAVDS	TEAD2	231	Q15562
VQDPSVFVTFPLEED	IARS1	201	P41252
EFIADPPSISAFDLD	SF3A1	151	Q15459
ETPEQPTAGDVFVLE	GTF3C3	111	Q9Y5Q9
VEPVSRFFEEVNDPA	ACADVL	106	P49748
PSDLVDQSIFNFIPE	CLOCK	146	O15516
DIPPDVDTEQDRVFF	CLUAP1	51	Q96AJ1
EIVSVIPNAVDPTDF	PIGA	201	P37287
NVVFIKTEDPDLPAF	PRPF8	336	Q6P2Q9
EQSSEEEFFPEELLP	TCEAL1	41	Q15170
VVPFDAASEVPVEEQ	TIMELESS	581	Q9UNS1
PVFNPNVFSEDEDDL	TULP4	656	Q9NRJ4
PIFDETFEFQVNLPE	PLCL1	776	Q15111
EPEDSIFFVPQDSII	TMEM215	191	Q68D42
SSPVEELPSLAFENF	REV3L	2146	O60673
FTVQDPTEAEPLTAA	UBA7	166	P41226
EPDETFIVPDSFLVA	SPSB1	166	Q96BD6
VDDLDEDTPPIVSQF	STIM2	481	Q9P246
FPPEVAVFEPSEAEI	TRBC1	6	P01850
DVDEPLEVFISAPRS	SP100	336	P23497
AVPEVELSDQPENTF	SERPINA7	366	P05543
FLEEPEDRTVAANTP	AXL	141	P30530
TLPFRPVTQEEDDDQ	SMC6	1076	Q96SB8
FPPVTNEELFLTSDQ	DCT	436	P40126
EAFQSVNPEFSPEAL	SLC28A1	621	O00337
NEIVTETSPFAPAFL	MAP2	331	P11137
ERFIEDLTDDSINPP	ZSCAN4	116	Q8NAM6
EPVTFADVAVVFTPE	ZNF333	201	Q96JL9
FQEEDFPALVSSVPK	ZNF598	481	Q86UK7
EENIPSSFTDVALPV	TMEM87B	516	Q96K49
TNPFPLLEDEDDLFT	WASHC2A	1196	Q641Q2
DDDDVVFIESIQPPS	ZMYM5	56	Q9UJ78
SDNSRFPLAVVEEPI	TRAPPC8	741	Q9Y2L5
TVDFDSAPSIQELPV	SUOX	411	P51687
AIFVNFEDEEVPKQP	GTF3C5	216	Q9Y5Q8
FPDISQESDSPFVFI	TRIP4	526	Q15650
AVDDVPFSIPAASEI	WDR12	16	Q9GZL7
MTPEFDEEVVFENSP	VEZT	1	Q9HBM0
FEEVPSLEQAPASIS	ZNF438	176	Q7Z4V0
EPLFPFNLDEFVTVD	ZNF638	1531	Q14966
PLASPIQDSVAFEDV	ZNF669	81	Q96BR6
FLSAPPQAEVTFEDV	ZNF34	26	Q8IZ26
VSMFVPAPEEFTDEQ	UNC79	1986	Q9P2D8
IPEEILGTEEFFDPT	VPS13D	466	Q5THJ4
DAFNSEDFPPVLEIQ	VPS13D	2556	Q5THJ4
VSNFDPDFIKEEPVL	PRKCH	641	P24723
SPIPTEDQFFKDIDT	LPIN2	106	Q92539
DPPDIDINATVALDF	MXRA5	351	Q9NR99
VFELPENEDMFSPSE	PPP1R9A	656	Q9ULJ8