Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-activated inward rectifier potassium channel activity

KCNJ8 KCNJ11

1.07e-046542GO:0015272
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 3-kinase activity

PIK3C2B PIK3CD

1.49e-047542GO:0035005
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3C2B PIK3CD

3.89e-0411542GO:0016303
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

4.29e-04363546GO:0106310
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDK18 PIK3C2B PIK3CD CLK4 MYLK4 SRPK2 RIPK4 CASK

5.96e-04709548GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK18 PIK3C2B PIK3CD CLK4 PARP3 MYLK4 SRPK2 RIPK4 CASK

8.48e-04938549GO:0016772
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNJ8 KCNJ11

9.51e-0417542GO:0099508
GeneOntologyMolecularFunctionkinase activity

CDK18 PIK3C2B PIK3CD CLK4 MYLK4 SRPK2 RIPK4 CASK

9.69e-04764548GO:0016301
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

1.25e-03446546GO:0004674
GeneOntologyCellularComponentinward rectifying potassium channel

KCNJ8 KCNJ11

3.77e-054532GO:0008282
DomainKinase-like_dom

CDK18 PIK3C2B PIK3CD CLK4 MYLK4 SRPK2 RIPK4 CASK

1.34e-04542538IPR011009
DomainPI3K_Ras-bd_dom

PIK3C2B PIK3CD

1.64e-047532IPR000341
DomainPI3K_rbd

PIK3C2B PIK3CD

1.64e-047532PF00794
DomainPI3K_RBD

PIK3C2B PIK3CD

1.64e-047532PS51546
DomainPI3K_rbd

PIK3C2B PIK3CD

1.64e-047532SM00144
DomainPI3K_C2_dom

PIK3C2B PIK3CD

2.19e-048532IPR002420
DomainPI3K_C2

PIK3C2B PIK3CD

2.19e-048532PF00792
DomainPI3K_C2

PIK3C2B PIK3CD

2.19e-048532PS51547
DomainPI3K_C2

PIK3C2B PIK3CD

2.19e-048532SM00142
DomainPI3Ka

PIK3C2B PIK3CD

2.81e-049532PF00613
Domain-

PIK3C2B PIK3CD

2.81e-0495321.25.40.70
DomainPI3Ka

PIK3C2B PIK3CD

2.81e-049532SM00145
DomainPIK_HELICAL

PIK3C2B PIK3CD

3.50e-0410532PS51545
DomainPI_Kinase

PIK3C2B PIK3CD

3.50e-0410532IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3C2B PIK3CD

3.50e-0410532IPR001263
DomainARM-type_fold

XPO5 PIK3C2B PIK3CD UBR4 HSPBP1 STAG2

3.83e-04339536IPR016024
DomainSer/Thr_kinase_AS

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

5.03e-04357536IPR008271
DomainPROTEIN_KINASE_ST

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

5.42e-04362536PS00108
DomainPkinase

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

7.08e-04381536PF00069
DomainPI3/4_kinase_CS

PIK3C2B PIK3CD

8.10e-0415532IPR018936
DomainK_chnl_inward-rec_Kir_cyto

KCNJ8 KCNJ11

9.24e-0416532IPR013518
Domain-

PIK3C2B PIK3CD

9.24e-04165321.10.1070.11
DomainIRK

KCNJ8 KCNJ11

9.24e-0416532PF01007
Domain-

KCNJ8 KCNJ11

9.24e-04165322.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ8 KCNJ11

9.24e-0416532IPR016449
DomainPI3Kc

PIK3C2B PIK3CD

9.24e-0416532SM00146
DomainPI3/4_kinase_cat_dom

PIK3C2B PIK3CD

1.17e-0318532IPR000403
DomainPI3_PI4_kinase

PIK3C2B PIK3CD

1.17e-0318532PF00454
DomainPI3_4_KINASE_3

PIK3C2B PIK3CD

1.17e-0318532PS50290
DomainPI3_4_KINASE_1

PIK3C2B PIK3CD

1.17e-0318532PS00915
DomainPI3_4_KINASE_2

PIK3C2B PIK3CD

1.17e-0318532PS00916
DomainPROTEIN_KINASE_ATP

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

1.84e-03459536PS00107
Domainzf-C2H2_6

ZNF490 ZNF652 ZNF615 ZNF844 ZNF442

1.93e-03314535PF13912
DomainProt_kinase_dom

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

2.53e-03489536IPR000719
DomainPROTEIN_KINASE_DOM

CDK18 CLK4 MYLK4 SRPK2 RIPK4 CASK

2.63e-03493536PS50011
DomainIg_E-set

KCNJ8 KCNJ11 PLXNA2

3.21e-03104533IPR014756
DomainS_TKc

CDK18 CLK4 MYLK4 SRPK2 CASK

3.44e-03359535SM00220
Pubmed

Disruption of Kir6.2-containing ATP-sensitive potassium channels impairs maintenance of hypoxic gasping in mice.

KCNJ8 KCNJ11

2.37e-06254217445233
Pubmed

ATP-sensitive K+ channels in pig urethral smooth muscle cells are heteromultimers of Kir6.1 and Kir6.2.

KCNJ8 KCNJ11

2.37e-06254218945825
Pubmed

Expression of ATP-sensitive potassium channels in human pregnant myometrium.

KCNJ8 KCNJ11

2.37e-06254221418633
Pubmed

Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models.

SLC12A2 PRKN

2.37e-06254224204848
Pubmed

Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.

KCNJ8 KCNJ11

2.37e-06254216501027
Pubmed

Kir6.1 Heterozygous Mice Exhibit Aberrant Amygdala-Dependent Cued Fear Memory.

KCNJ8 KCNJ11

2.37e-06254231808063
Pubmed

Kir6.2-containing ATP-sensitive K(+) channel is required for cardioprotection of resveratrol in mice.

KCNJ8 KCNJ11

2.37e-06254224498880
Pubmed

Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice.

KCNJ8 KCNJ11

2.37e-06254234715352
Pubmed

Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity.

CTCF STAG2

2.37e-06254221444719
Pubmed

Molecular and functional characterization of the endothelial ATP-sensitive potassium channel.

KCNJ8 KCNJ11

2.37e-06254228893911
Pubmed

KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease-related pathology.

KCNJ8 KCNJ11

2.37e-06254237129980
Pubmed

Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson's disease.

KCNJ8 KCNJ11

2.37e-06254229540778
Pubmed

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

SLC12A2 KCNJ8 KCNJ11

5.34e-062254318391953
Pubmed

Molecular basis and characteristics of KATP channel in human corporal smooth muscle cells.

KCNJ8 KCNJ11

7.09e-06354212934053
Pubmed

Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1.

KCNJ8 KCNJ11

7.09e-06354219139106
Pubmed

Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system.

KCNJ8 KCNJ11

7.09e-06354221984445
Pubmed

Single-molecule imaging reveals a direct role of CTCF's zinc fingers in SA interaction and cluster-dependent RNA recruitment.

CTCF STAG2

7.09e-06354238742641
Pubmed

Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activity.

KCNJ8 KCNJ11

7.09e-06354218001767
Pubmed

Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.

KCNJ8 KCNJ11

7.09e-06354210559219
Pubmed

Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.

KCNJ8 KCNJ11

7.09e-0635429130167
Pubmed

A mechanism for ATP-sensitive potassium channel diversity: Functional coassembly of two pore-forming subunits.

KCNJ8 KCNJ11

7.09e-06354211136227
Pubmed

Expression of functional Kir6.1 channels regulates glutamate release at CA3 synapses in generation of epileptic form of seizures.

KCNJ8 KCNJ11

7.09e-06354217883401
Pubmed

Cohesin mediates transcriptional insulation by CCCTC-binding factor.

CTCF STAG2

1.42e-05454218235444
Pubmed

STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma.

CTCF STAG2

1.42e-05454233930311
Pubmed

Assembly limits the pharmacological complexity of ATP-sensitive potassium channels.

KCNJ8 KCNJ11

1.42e-05454211825905
Pubmed

Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium.

KCNJ8 KCNJ11

1.42e-05454212356945
Pubmed

Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers.

CTCF STAG2

1.42e-05454234518235
Pubmed

The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies.

PRKN CASK

1.42e-05454221590270
Pubmed

Seven in absentia homolog 2 (Siah2) protein is a regulator of NF-E2-related factor 2 (Nrf2).

SIAH2 KEAP1

1.42e-05454223645672
Pubmed

Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart.

KCNJ8 KCNJ11

1.42e-05454216085792
Pubmed

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.

KCNJ8 KCNJ11

1.42e-05454228842488
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SLC12A2 IMPDH1 RTCB CTCF SYNE1 ZNF652 CLK4 TWNK SRPK2 STAG2 CASK

1.57e-051497541131527615
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

THOP1 FMO5 SLC12A2 RASGRP3 TAF1B STAG2

2.10e-0536354614691545
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RTCB TAF1B SMC6 SUPT16H EXO1 TWNK SRPK2 KEAP1

2.13e-0575954835915203
Pubmed

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer.

PIK3C2B PIK3CD

2.36e-05554220197460
Pubmed

Functional proteomics mapping of a human signaling pathway.

XPO5 MAN1C1 UBR4 TWNK SIAH2 KEAP1 CASK

3.50e-0559154715231748
Pubmed

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain.

PRKN CASK

3.54e-05654211679592
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

CTCF SUPT16H TWNK SRPK2 KEAP1

4.46e-0525154528077445
Pubmed

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.

PIK3C2B PIK3CD

4.94e-05754218755982
Pubmed

A protein interaction landscape of breast cancer.

XPO5 CTCF UBR4 SUPT16H ACOT7 HSPBP1 KEAP1

5.45e-0563454734591612
Pubmed

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.

KCNJ8 KCNJ11

6.59e-05854219805629
Pubmed

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels.

PRKN CASK

6.59e-05854217553932
Pubmed

S5a/Rpn10, a UIM-protein, as a universal substrate for ubiquitination.

SIAH2 PRKN

8.46e-05954222350919
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CDK18 SLC12A2 SYNE1 UBR4 SUPT16H TWNK SRPK2 HSPBP1 CEMIP2 CASK

8.50e-051487541033957083
Pubmed

Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.

SMC6 STAG2

1.06e-041054222751501
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3C2B PIK3CD

1.06e-04105428636073
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3C2B PIK3CD

1.06e-04105428798481
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3C2B PIK3CD

1.06e-04105429247029
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

PIK3C2B PIK3CD

1.29e-041154216081599
Pubmed

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.

PIK3C2B PIK3CD

1.29e-04115429708406
Pubmed

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.

PIK3C2B PIK3CD

1.29e-041154210985305
Pubmed

Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.

PIK3C2B PIK3CD

1.29e-041154212584329
Pubmed

Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.

PIK3C2B PIK3CD

1.29e-04115429808187
Pubmed

Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.

PIK3C2B PIK3CD

1.55e-041254214602571
Pubmed

Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.

PIK3C2B PIK3CD

1.55e-041254216514418
Pubmed

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

PIK3C2B PIK3CD

1.55e-041254210208934
Pubmed

Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.

PIK3C2B PIK3CD

1.55e-041254212077252
Pubmed

Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.

PIK3C2B PIK3CD

1.55e-04125429341793
Pubmed

Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.

PIK3C2B PIK3CD

1.55e-041254212551992
Pubmed

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.

SIAH2 PRKN

1.83e-041354219240029
Pubmed

HIV-1 Nef in macrophage-mediated disease pathogenesis.

PIK3C2B PIK3CD

1.83e-041354223215766
Pubmed

Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.

PIK3C2B PIK3CD

1.83e-04135429394803
Pubmed

Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.

PIK3C2B PIK3CD

2.13e-041454217157319
Pubmed

HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.

PIK3C2B PIK3CD

2.45e-041554218854243
Pubmed

International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.

KCNJ8 KCNJ11

2.45e-041554216382105
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PIK3C2B PIK3CD

2.80e-041654216524887
Pubmed

HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.

PIK3C2B PIK3CD

2.80e-041654211289809
Pubmed

Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.

PIK3C2B PIK3CD

2.80e-041654220019835
Pubmed

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

PIK3C2B PIK3CD

2.80e-041654221029719
Pubmed

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.

CTCF STAG2

2.80e-041654222780989
Pubmed

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.

PIK3C2B PIK3CD

2.80e-041654220818790
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

IMPDH1 PIK3C2B PIK3CD KCNJ11 UBR4 TWNK SIAH2 MYRF

2.88e-04110554835748872
Pubmed

Synergistic cooperation between methamphetamine and HIV-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes.

PIK3C2B PIK3CD

3.17e-041754223251686
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PIK3C2B PIK3CD

3.17e-041754212960231
Pubmed

Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.

PIK3C2B PIK3CD

3.17e-041754218453587
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

TRMU PIK3C2B UBR4 TWNK KEAP1 CASK

3.41e-0460454638803224
Pubmed

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.

PIK3C2B PIK3CD

3.56e-041854212526811
Pubmed

HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.

PIK3C2B PIK3CD

3.98e-041954224073214
Pubmed

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.

IGFBP4 CEMIP2 CASK

4.29e-049454337468549
Pubmed

Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.

PIK3C2B PIK3CD

4.88e-04215429446795
Pubmed

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.

THOP1 PRKN KEAP1

4.99e-049954331723608
Pubmed

HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.

PIK3C2B PIK3CD

5.36e-042254211994280
Pubmed

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.

PIK3C2B PIK3CD

5.36e-042254211154208
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF490 XPO5 SYNE1

5.61e-0410354310574462
Pubmed

Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.

PRKN CASK

5.86e-042354216637659
Pubmed

HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathway.

PIK3C2B PIK3CD

5.86e-042354223301033
Pubmed

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.

PIK3C2B PIK3CD

5.86e-042354219047410
Pubmed

A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels.

FMO5 PRKN

6.39e-042454225240745
Pubmed

Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.

PIK3C2B PIK3CD

6.94e-042554215689238
Pubmed

Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy.

PIK3C2B PIK3CD

6.94e-042554217632570
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CTCF SYNE1 UBR4 SUPT16H SRPK2 KEAP1 CASK

6.96e-0496354728671696
Pubmed

The protein interaction landscape of the human CMGC kinase group.

CDK18 CLK4 TAF1B SUPT16H SRPK2 CASK

7.12e-0469554623602568
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

THOP1 RTCB XPO5 UBR4 ACOT7 HSPBP1 CASK

7.44e-0497454728675297
Pubmed

Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.

IGFBP4 CTCF

7.51e-042654226244796
Pubmed

Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.

RTCB XPO5

7.51e-042654223181366
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

PIK3C2B PIK3CD UBR4 HSPBP1

7.83e-0426654419380743
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PIK3C2B PIK3CD

8.10e-042754211156964
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

RTCB UBR4 ACOT7 SRPK2

8.17e-0426954429511261
Pubmed

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.

IGFBP4 ACOT7

1.00e-033054227133129
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

PIK3C2B UBR4 SUPT16H STAG2

1.05e-0328854423383273
Cytoband19p13.2

ZNF490 KEAP1 ZNF844 ZNF442

1.57e-0422954419p13.2
Cytoband6p25.2

SLC22A23 MYLK4

3.09e-04225426p25.2
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PIK3CD MAN1C1 UBR4 ACOT7 CFAP74

1.23e-03681545chr1p36
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ZNF490 THOP1 KEAP1 ZNF844 ZNF442

2.44e-03797545chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr1q32

CDK18 PIK3C2B PLXNA2

4.88e-03290543chr1q32
CytobandEnsembl 112 genes in cytogenetic band chr6p25

SLC22A23 MYLK4

5.31e-0392542chr6p25
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2B PIK3CD

1.19e-048382831
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ8 KCNJ11

5.07e-0416382276
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF490 CTCF ZNF652 ZNF615 ZNF844 ZNF442

3.58e-0371838628
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.59e-06192545dfa6adc776621f4b51d731b796c0421855b2297c
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.68e-061935454893b922e129711d5886bd4f3ee106e9e7065971
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 PIK3C2B RASGRP3 PLXNA2 CEMIP2

3.68e-06193545d485634c564b268e344b6a2863c26f6adaec9e38
ToppCelldroplet-Lung-nan-21m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.68e-06193545ae35c5757a88b02f8b9f94a0af4c3396ca828cc3
ToppCelldroplet-Lung-21m-Endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-06194545b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-061945451ac52b00ea0b0ddbd04f5d85fa8c086980a78926
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC12A2 IGFBP4 KCNJ8 SMC6 CEMIP2

3.77e-0619454578dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCelldroplet-Lung-nan-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-06194545faaa7f18667e8943528fd0e92b7988e5b0607b54
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-06194545fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-06194545f6c9cc362ccdbc7e790f7c8d1c56cab3557c5306
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.77e-06194545b49c19c33ad2e391d9367a4a2695b2fe87dd8a08
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9 CEMIP2

3.87e-0619554527d1f228103ff5d8941aa8a8d15726cd09298a30
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC12A2 TDO2 ADGRF1 MYRF

2.31e-0513754480f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCellHippocampus-Endothelial-MURAL|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2R1 KCNJ8 PARP3 MYLK4

4.04e-051585442d73b5e59c650c603fec6223b1c51f0962f7bc81
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2R1 KCNJ8 PARP3 MYLK4

4.04e-051585447f4a644534b78f7e7539cae1fd895dad6f96862b
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP4 PIK3CD KCNJ8 TSPAN9

5.01e-0516754410c9fab3573c2948081aac2cec1798e46e59e38a
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP4 PIK3CD KCNJ8 TSPAN9

5.25e-051695442de213b083f57f47be58427c0ce127fee9f85caa
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A2 PIK3C2B SYNE1 CEMIP2

6.01e-05175544cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellAT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FMO5 IGFBP4 SYNE1 ADGRF1

6.85e-05181544ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SLC12A2 SYNE1 PLXNA2 TSPAN9

6.85e-05181544c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IMPDH1 RASGRP3 TSPAN9 CEMIP2

6.85e-051815449cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellBAL-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

IGFBP4 RASGRP3 SMC6 ZNF615

6.85e-05181544f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCellP28-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IMPDH1 IGFBP4 RASGRP3 CEMIP2

7.00e-05182544db5d6c5e7d59734653906b126f2c1d57461a5290
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 KCNJ8 TWNK

7.00e-05182544c84f44391932080df31c8765e363c3dff64b2bd1
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IGFBP4 RTCB RASGRP3 SMC6

7.15e-05183544dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 ACOT7 TSPAN9

7.61e-05186544744bf39af2fb5a7454477174d7755a6d78cd279f
ToppCellfacs-SCAT-Fat-3m-Epithelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 RIPK4 CEMIP2

7.77e-0518754408f2ecce3c08f35d995187b21bb7407a99dee4c2
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 SYNE1 RASGRP3 CEMIP2

7.77e-0518754452ffd4be374e329ac8d321063f061b826d252956
ToppCellfacs-SCAT-Fat-3m-Epithelial-epithelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 RIPK4 CEMIP2

7.77e-05187544939a068ac0913b9eeb5da4a9cb267d51cb711999
ToppCellfacs-SCAT-Fat-3m-Epithelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 RIPK4 CEMIP2

7.77e-05187544e02e7f608506b9a48384f07727944f1cb8f7c575
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMO5 IGFBP4 RASGRP3 CEMIP2

7.93e-0518854459f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCellfacs-Lung|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

7.93e-05188544f7292fc8e914f222828dcdb0a017d716207a97f6
ToppCellfacs-Lung|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

7.93e-05188544e2b6e14579ec649a2bc106d9c99bb78ceb16ede3
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 ACOT7 HSPBP1

8.10e-05189544533685a921a65d84107d8d33c43b4fffde019143
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 PIK3C2B RASGRP3 CEMIP2

8.10e-051895449da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 ACOT7 HSPBP1

8.10e-05189544dca56ab02bf0505f9a352ff907edaef30906d854
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMO5 IGFBP4 RASGRP3 CEMIP2

8.10e-05189544360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellfacs-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.26e-05190544d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 ACOT7 HSPBP1

8.26e-05190544a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP3 PLXNA2 TSPAN9 CEMIP2

8.26e-0519054438a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

IMPDH1 PIK3C2B RASGRP3 CEMIP2

8.26e-051905441357bd4527399d7013ee33272bda7453f472999a
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC12A2 SYNE1 MYLK4 TSPAN9

8.26e-051905440a351609a72fd638c84b2435782e312ee6a33aac
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

IMPDH1 PIK3C2B RASGRP3 CEMIP2

8.26e-051905445130fb325f80f591b9b36beacb8072c4472304f2
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 SYNE1 RASGRP3 CEMIP2

8.26e-05190544e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP3 PLXNA2 TSPAN9 CEMIP2

8.26e-05190544bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP3 PLXNA2 TSPAN9 CEMIP2

8.26e-05190544d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 RIPK4 TSPAN9

8.43e-05191544b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC12A2 SYNE1 MYLK4 TSPAN9

8.43e-05191544f229abf69a1217194f74b0502486907e07dba989
ToppCelldroplet-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 TSPAN9 CEMIP2

8.60e-0519254442e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 PIK3C2B RASGRP3 CEMIP2

8.78e-05193544826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.78e-05193544ff048e7fbab95d7914f3a636f6f014e7115d63d8
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 CEMIP2

8.78e-051935447cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 PIK3C2B RASGRP3 CEMIP2

8.78e-0519354487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellEC-Sinusoidal_ECs|EC / Lineage and Cell class

IGFBP4 KCNJ8 ACOT7 SIAH2

8.78e-051935441291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IGFBP4 PIK3C2B RASGRP3 CEMIP2

8.78e-05193544ad2df9b77999780860141be6ec366afc0172a331
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.78e-05193544ee4b31d9c92f8fd0d3ddb5e723b82300fcb459d1
ToppCelldroplet-Lung-nan-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.78e-051935442f387fb763448b7c351da19a55765375e782c790
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.78e-051935447401e276b644b254c692160d0e7417ec28d50aa4
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

8.78e-051935448748af38bfbbbb431ff9d9d5fa75934b5869293a
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 IGFBP4 RASGRP3 TSPAN9

8.78e-05193544ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9

8.95e-051945440d72cb6183062d48488c73320e48044d070fbcac
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THOP1 IMPDH1 IGFBP4 EXO1

8.95e-05194544c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 TSPAN9 CEMIP2

8.95e-05194544ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 RASGRP3 TSPAN9

8.95e-051945441a637809c0ec97374839c3476527e87eea75ed20
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CDK18 IGFBP4 RASGRP3 KCNJ8

8.95e-051945444428b472c2042f88eae028b1770767512a515b75
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 TSPAN9 CEMIP2

8.95e-05194544627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCelldroplet-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 IGFBP4 TSPAN9 CEMIP2

8.95e-05194544fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.13e-0519554452b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.13e-05195544e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.13e-051955445b84fd5be31386eb1d6048bbf28626032361842e
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B RASGRP3 PLXNA2 CEMIP2

9.13e-0519554430c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.32e-051965449e737eaa98fd49972fce64d1d4a4d1f34b9bcb96
ToppCellfacs-Lung-ENDOMUCIN-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.32e-05196544f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCelldroplet-Lung-30m-Endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.32e-0519654458871891185aa7e1e4ab9b99cd25c1ca3c932cc8
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B RASGRP3 TSPAN9 CEMIP2

9.32e-0519654481900dcc9451ff6606ec940c16b559d73247590e
ToppCellfacs-Lung-ENDOMUCIN|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.32e-0519654469f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IMPDH1 RASGRP3 TSPAN9 CEMIP2

9.32e-0519654499a7f2e57774884216525897dcd32a289107548b
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLA2R1 IGFBP4 KCNJ8 TSPAN9

9.32e-0519654473f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

9.50e-05197544f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B RASGRP3 PLXNA2 CEMIP2

9.50e-05197544d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 RASGRP3 KCNJ8 TSPAN9

9.50e-051975444e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B RASGRP3 PLXNA2 CEMIP2

9.50e-05197544412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

XPO5 ZNF615 ADGRF1 PLXNA2

9.50e-051975446b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 ACOT7 MYRF

9.50e-051975447b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK18 SLC12A2 ACOT7 MYRF

9.69e-0519854497ae237f955fd5fbd01d06aafe89ef9e6f777a9a
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

9.88e-0519954441f046646fff65b7e51b63d3204f76ef32054781
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

9.88e-05199544ef7f7f7c861827574b120f48cf4052c563929081
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

CDK18 SLC12A2 RASGRP3 MYRF

1.01e-042005444dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 IMPDH1 SYNE1 CEMIP2

1.01e-04200544032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell10x5'v1-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

1.01e-042005442488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 IMPDH1 SYNE1 CEMIP2

1.01e-0420054468fce28690246895fd33354b30960ebcc31aa4cc
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CDK18 SLC12A2 RASGRP3 MYRF

1.01e-0420054426b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 IMPDH1 SYNE1 CEMIP2

1.01e-04200544376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

1.01e-04200544ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CDK18 SLC12A2 RASGRP3 MYRF

1.01e-042005441314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 IMPDH1 SYNE1 CEMIP2

1.01e-042005447fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CDK18 SLC12A2 RASGRP3 MYRF

1.01e-042005448b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CDK18 SLC12A2 RASGRP3 MYRF

1.01e-04200544272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell10x5'v1-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGFBP4 KCNJ8 TSPAN9 CEMIP2

1.01e-04200544e786544cf6f891550c4be55ebb4928c92297b504
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 IMPDH1 SYNE1 CEMIP2

1.01e-04200544878bbbe32e3602723aa14ef32877ab2453b8c6e5
Drugthiophenone

SYNE1 TDO2

5.52e-062542CID009548690
Drug3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A

FMO5 MAN1C1 SYNE1 PARP3 ADAM8 MYRF

6.90e-061965466367_DN
DrugBaclofen (R,S) [1134-47-0]; Down 200; 18.8uM; PC3; HT_HG-U133A

TRMU FMO5 ZNF442 DMAC2L PLXNA2 CEMIP2

7.11e-061975466313_DN
DrugThiamylal

KCNJ8 KCNJ11

1.65e-053542DB01154
DiseaseLeukemia, Megakaryoblastic, of Down Syndrome

CTCF STAG2

8.80e-058532C1860789
Diseasepipecolate measurement

MYLK4 PLXNA2

2.44e-0413532EFO_0021006
Diseaseegg allergy measurement, parental genotype effect measurement

ZNF652 TAF1B

2.44e-0413532EFO_0005939, EFO_0007018
DiseaseGlioblastoma Multiforme

SRPK2 PRKN STAG2

1.06e-03111533C1621958
Diseaseacylcarnitine measurement

SLC22A23 ACOT7 MYRF

1.56e-03127533EFO_0005059
DiseaseParkinsonism (biomarker_via_orthology)

KCNJ8 KCNJ11

1.71e-0334532DOID:0080855 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LHGFVHGGVTMKLMD

ACOT7

241

O00154
ICHARFTQSGTMKMH

CTCF

411

P49711
HHMAQHLMMAVGFCL

ADGRF1

691

Q5T601
DHCGNLMSMHNVKIF

CDK18

231

Q07002
VGVACTMAHEMGHNL

ADAM8

326

P78325
CIMSIGFDHMEGLEH

DMAC2L

111

Q99766
VIGMKCGAHHVGYMF

PARP3

426

Q9Y6F1
EGRHKAFSTCGSHMM

OR5M11

231

Q96RB7
NHCIVARIMHGGMIH

CASK

511

O14936
AVMLGCIFMKTAQAH

KCNJ8

171

Q15842
HVLQKKESMGMCFIG

TRMU

211

O75648
AIMLGCIFMKTAQAH

KCNJ11

161

Q14654
LTGQHKVMVHVGGMV

PLXNA2

1206

O75051
LFMKQICEGIRHMHQ

MYLK4

206

Q86YV6
CHVIIDNLQFMMGHE

TWNK

511

Q96RR1
AMALMGGIGFIHHNC

IMPDH1

81

P20839
IMLKTTGHMFHIDFG

PIK3C2B

1201

O00750
KEMNVFDGVMVCTGH

FMO5

136

P49326
FGGHIMIMKNFTSVH

CEMIP2

516

Q9UHN6
HKMGHLACFSGGMIA

MAN1C1

446

Q9NR34
ACGKIVSHTHLGVNM

HAUS6

31

Q7Z4H7
SMGEKCVLHVMNGAV

KEAP1

146

Q14145
CIDHGMDGMHVAVKI

CLK4

176

Q9HAZ1
SHQILLKGAACQHMM

CFAP74

1466

Q9C0B2
MMNHLPFCGSNVVVH

OR52I1

166

Q8NGK6
HPEHKGTLCSMGMVQ

HSPBP1

261

Q9NZL4
MGIDHKGQVCVMIHS

RTCB

246

Q9Y3I0
CHVPVEKNGGCMHMK

PRKN

421

O60260
QCQGFHEMSHGLLLM

SYNE1

8551

Q8NF91
YNHVCMVHRMLGSKA

TDO2

326

P48775
HCFARSMMGHEVKVP

SLC22A23

446

A1A5C7
MHSLTCHVVKMTGMG

TAF1B

321

Q53T94
CHVVKMTGMGEVDFL

TAF1B

326

Q53T94
HCKMGPGFIHNFQEM

RASGRP3

486

Q8IV61
MQSCFGHHFMLVLEK

SIAH2

221

O43255
HTLMHGQGVCMELAE

IGFBP4

91

P22692
SDKNHMHFGAITCAM

SUPT16H

261

Q9Y5B9
IIHETAVGMNFLHCM

RIPK4

121

P57078
VGFCMKFVNMLLSHG

EXO1

56

Q9UQ84
LHTIKGNTHGMPCMF

PLA2R1

166

Q13018
GKGFSMKHCLMVHQR

ZNF615

406

Q8N8J6
CGEVFMHQVSLNRHM

ZNF490

161

Q9ULM2
GCKGVVTAEMFRHMQ

STAG2

126

Q8N3U4
FTKNVGLMICGHVHM

SLC12A2

811

P55011
DFKISGMNGIHVCMV

SRPK2

151

P78362
VLKGLQMHGQHDGCM

XPO5

1076

Q9HAV4
YCRGSTHHMKVLMKQ

PIK3CD

671

O00329
IHLKNFMCHSMLGPF

SMC6

51

Q96SB8
RHMIMHNGDGTYKCK

ZNF844

186

Q08AG5
MIMHTGDGPHKCKVC

ZNF442

396

Q9H7R0
RSHMSIHIGHKQFMC

ZNF652

401

Q9Y2D9
GHVMHQLCSQAEFAM

THOP1

476

P52888
NANVMHGKHVMILEC

UBR4

1581

Q5T4S7
HGKHVMILECTCHIM

UBR4

1586

Q5T4S7
NKHVLGTVGMCILIM

TSPAN9

201

O75954
LVVHGNVKVMGSLMH

MYRF

571

Q9Y2G1