Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

5.75e-0644112913GO:0016887
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

4.14e-0521292GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

4.14e-0521292GO:0097259
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

4.40e-0561412914GO:0140657
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 KIF18A DNAH3 KIF1A DYNC2H1

9.00e-05701295GO:0003777
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ABCA3 ABCA4 ATP8B2

9.10e-05141293GO:0140333
GeneOntologyMolecularFunctionflippase activity

ABCA3 ABCA4 ATP8B2

1.68e-04171293GO:0140327
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH3 DYNC2H1

2.00e-04181293GO:0008569
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

2.46e-0441292GO:0005219
GeneOntologyMolecularFunctionaliphatic amine oxidase activity

MAOB AOC2

2.46e-0441292GO:0052595
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3

4.09e-0451292GO:0052871
GeneOntologyMolecularFunctionphosphatidylcholine flippase activity

ABCA3 ATP8B2

6.11e-0461292GO:0140345
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

6.11e-0461292GO:0048763
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH3 DYNC2H1

7.67e-04281293GO:0051959
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA3 ABCA4 ATP8B2

7.67e-04281293GO:0140326
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3

8.51e-0471292GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3

8.51e-0471292GO:0018685
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 KIF18A DNAH3 KIF1A DYNC2H1

1.02e-031181295GO:0003774
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIK1 RYR2 RYR3

1.04e-03311293GO:0099604
GeneOntologyMolecularFunctionadenosine receptor binding

ADA2 USP4

1.13e-0381292GO:0031685
GeneOntologyMolecularFunctionstructural constituent of postsynapse

SPTBN2 ACTB ACTG1

1.14e-03321293GO:0099186
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCA3 ABCA4 PRELID3B ATP8B2

1.35e-03741294GO:0005548
GeneOntologyMolecularFunctionprimary methylamine oxidase activity

MAOB AOC2

1.45e-0391292GO:0008131
GeneOntologyMolecularFunctioncalcium channel activity

TRPM7 GRIK1 RYR2 RYR3 TRPM1

1.51e-031291295GO:0005262
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

1.54e-0377512913GO:0017111
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH3 DYNC2H1

1.74e-03371293GO:0045505
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3

1.80e-03101292GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3

1.80e-03101292GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3

1.80e-03101292GO:0102033
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

ACTB ACTG1

2.19e-03111292GO:0098973
GeneOntologyMolecularFunctionstructural constituent of synapse

SPTBN2 ACTB ACTG1

2.52e-03421293GO:0098918
GeneOntologyMolecularFunctionhistone H3 kinase activity

JAK2 AURKA

2.62e-03121292GO:0140996
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM7 GRIK1 RYR2 RYR3 TRPM1

3.00e-031511295GO:0015085
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

3.07e-0383912913GO:0016462
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3

3.08e-03131292GO:0016713
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

3.10e-0384012913GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF18A DNAH3 ABCA3 ERCC3 ABCA4 KIF1A DYNC2H1 DDX60 SMCHD1 ACTB BTAF1 ATP8B2 SMC1B

3.10e-0384012913GO:0016818
GeneOntologyBiologicalProcesscardiac muscle cell fate commitment

TBX3 TBX18 TBX5

1.91e-0591283GO:0060923
GeneOntologyBiologicalProcesscardiac pacemaker cell development

TBX3 TBX18 TBX5

2.71e-05101283GO:0060926
GeneOntologyBiologicalProcessregulation of organic acid transport

DPYSL2 CYP4F2 GRIK1 PLA2R1 SLC12A2 SV2A

4.44e-051031286GO:0032890
GeneOntologyBiologicalProcesspositive regulation of organic acid transport

DPYSL2 CYP4F2 GRIK1 PLA2R1 SLC12A2

4.48e-05631285GO:0032892
GeneOntologyBiologicalProcesscardiac pacemaker cell differentiation

TBX3 TBX18 TBX5

4.93e-05121283GO:0060920
GeneOntologyBiologicalProcesssinoatrial node development

TBX3 TBX18 TBX5

6.38e-05131283GO:0003163
GeneOntologyBiologicalProcesscardiac cell fate commitment

TBX3 TBX18 TBX5

8.08e-05141283GO:0060911
GeneOntologyBiologicalProcessatrioventricular bundle cell differentiation

TBX3 TBX5

1.14e-0431282GO:0003167
GeneOntologyBiologicalProcesscardiac pacemaker cell fate commitment

TBX18 TBX5

1.14e-0431282GO:0060927
GeneOntologyBiologicalProcessregulation of SA node cell action potential

RYR2 TBX18

1.14e-0431282GO:0098907
GeneOntologyBiologicalProcessmammary gland epithelium development

TBX3 JAK2 SLC12A2 BRCA2 CSMD1

1.77e-04841285GO:0061180
GeneOntologyBiologicalProcessmuscle cell fate commitment

TBX3 TBX18 TBX5

1.78e-04181283GO:0042693
GeneOntologyBiologicalProcessHis-Purkinje system cell differentiation

TBX3 TBX5

2.27e-0441282GO:0060932
GeneOntologyBiologicalProcessregulation of transepithelial transport

ACTB ACTG1

2.27e-0441282GO:0150111
GeneOntologyCellularComponentpostsynapse

ARHGAP32 DPYSL2 KIF1A SYNE1 SPTBN2 ACTB RAPGEF4 ACTG1 MPDZ GRIK1 ZZEF1 JAK2 AURKA PLEKHA5 UTRN EXOC4 SEZ6

2.13e-04101813117GO:0098794
GeneOntologyCellularComponentsomatodendritic compartment

ARHGAP32 DPYSL2 MAOB KIF1A TRPM7 MARK3 SYNE1 SPTBN2 RAPGEF4 MPDZ GRIK1 RRM1 AURKA SLC12A2 SV2A TRPM1 WDFY3 EXOC4 SEZ6

2.35e-04122813119GO:0036477
GeneOntologyCellularComponentchromosomal region

KIF18A NCAPD3 SMCHD1 ACTB TERF1 NLRP2 AURKA BRCA2 SMC1B NSMCE1

3.26e-0442113110GO:0098687
GeneOntologyCellularComponentmicrotubule associated complex

DNHD1 KIF18A DNAH3 KIF1A DYNC2H1 AURKA

5.38e-041611316GO:0005875
GeneOntologyCellularComponentpostsynaptic cytoskeleton

SPTBN2 ACTB ACTG1

5.63e-04261313GO:0099571
GeneOntologyCellularComponentgerminal vesicle

NCAPD3 AURKA

5.75e-0461312GO:0042585
GeneOntologyCellularComponentcell body

DPYSL2 MAOB KIF1A TRPM7 SPTBN2 RAPGEF4 ACTG2 GRIK1 RRM1 AURKA SLC12A2 SV2A WDFY3 EXOC4 SEZ6

7.24e-0492913115GO:0044297
GeneOntologyCellularComponentneuronal cell body

DPYSL2 MAOB KIF1A TRPM7 SPTBN2 RAPGEF4 GRIK1 RRM1 AURKA SLC12A2 SV2A WDFY3 EXOC4 SEZ6

7.63e-0483513114GO:0043025
GeneOntologyCellularComponentdense body

ACTB ACTG1

8.02e-0471312GO:0097433
DomainTF_T-box

TBX15 TBX3 TBX18 TBX5

4.97e-06171304IPR001699
DomainTBOX

TBX15 TBX3 TBX18 TBX5

4.97e-06171304SM00425
DomainTF_T-box_CS

TBX15 TBX3 TBX18 TBX5

4.97e-06171304IPR018186
Domain-

TBX15 TBX3 TBX18 TBX5

4.97e-061713042.60.40.820
DomainTBOX_3

TBX15 TBX3 TBX18 TBX5

4.97e-06171304PS50252
DomainT-box

TBX15 TBX3 TBX18 TBX5

4.97e-06171304PF00907
DomainTBOX_1

TBX15 TBX3 TBX18 TBX5

4.97e-06171304PS01283
DomainTBOX_2

TBX15 TBX3 TBX18 TBX5

4.97e-06171304PS01264
DomainAPC_su10/DOC_dom

CUL9 CUL7 ZZEF1

1.13e-0571303IPR004939
DomainDOC

CUL9 CUL7 ZZEF1

1.13e-0571303PS51284
DomainANAPC10

CUL9 CUL7 ZZEF1

1.13e-0571303PF03256
DomainAPC10

CUL9 CUL7 ZZEF1

1.13e-0571303SM01337
DomainACTINS_1

ACTB ACTG1 ACTG2

1.80e-0581303PS00406
DomainDynein_HC_stalk

DNHD1 DNAH3 DYNC2H1

1.13e-04141303IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH3 DYNC2H1

1.13e-04141303IPR013602
DomainDHC_N2

DNHD1 DNAH3 DYNC2H1

1.13e-04141303PF08393
DomainMT

DNHD1 DNAH3 DYNC2H1

1.13e-04141303PF12777
DomainDHC_fam

DNHD1 DNAH3 DYNC2H1

1.41e-04151303IPR026983
DomainDynein_heavy

DNHD1 DNAH3 DYNC2H1

1.41e-04151303PF03028
DomainDynein_heavy_dom

DNHD1 DNAH3 DYNC2H1

1.41e-04151303IPR004273
DomainCul7

CUL9 CUL7

1.44e-0431302PF11515
DomainSV2

SV2A SV2C

1.44e-0431302IPR022308
DomainRyanodine_rcpt

RYR2 RYR3

1.44e-0431302IPR003032
DomainCPH_domain

CUL9 CUL7

1.44e-0431302IPR021097
DomainRyanrecept_TM4-6

RYR2 RYR3

1.44e-0431302IPR009460
DomainRyR

RYR2 RYR3

1.44e-0431302PF02026
DomainPentapeptide_4

SV2A SV2C

1.44e-0431302PF13599
DomainRR_TM4-6

RYR2 RYR3

1.44e-0431302PF06459
DomainRyan_recept

RYR2 RYR3

1.44e-0431302IPR013333
DomainActin_CS

ACTB ACTG1 ACTG2

1.73e-04161303IPR004001
DomainACTINS_2

ACTB ACTG1 ACTG2

2.09e-04171303PS00432
DomainActin/actin-like_CS

ACTB ACTG1 ACTG2

2.49e-04181303IPR020902
Domain5peptide_repeat

SV2A SV2C

2.86e-0441302IPR001646
DomainTRPM_tetra

TRPM7 TRPM1

2.86e-0441302PF16519
DomainTRPM_tetra

TRPM7 TRPM1

2.86e-0441302IPR032415
DomainACTINS_ACT_LIKE

ACTB ACTG1 ACTG2

2.94e-04191303PS01132
DomainMunc13_dom-2

UNC13B BAIAP3

4.74e-0451302IPR014772
DomainMHD2

UNC13B BAIAP3

4.74e-0451302PS51259
DomainMunc13_subgr_dom-2

UNC13B BAIAP3

4.74e-0451302IPR019558
DomainMembr_traf_MHD

UNC13B BAIAP3

4.74e-0451302PF10540
Domainp53-like_TF_DNA-bd

TBX15 TBX3 TBX18 TBX5

5.04e-04531304IPR008967
DomainSpectrin

SYNE1 SPTBN2 UTRN

5.27e-04231303PF00435
DomainACTININ_2

SYNE1 SPTBN2 UTRN

5.27e-04231303PS00020
DomainACTININ_1

SYNE1 SPTBN2 UTRN

5.27e-04231303PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN2 UTRN

5.27e-04231303IPR001589
DomainRIH_assoc-dom

RYR2 RYR3

7.08e-0461302IPR013662
DomainSMC_hinge

SMCHD1 SMC1B

7.08e-0461302SM00968
DomainIns145_P3_rec

RYR2 RYR3

7.08e-0461302PF08709
DomainRIH_assoc

RYR2 RYR3

7.08e-0461302PF08454
DomainRIH_dom

RYR2 RYR3

7.08e-0461302IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

7.08e-0461302IPR014821
DomainSMC_hinge

SMCHD1 SMC1B

7.08e-0461302PF06470
DomainRyanodine_recept-rel

RYR2 RYR3

7.08e-0461302IPR015925
Domain-

RYR2 RYR3

7.08e-04613021.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

7.08e-0461302PF01365
DomainSMC_hinge

SMCHD1 SMC1B

7.08e-0461302IPR010935
DomainMunc13_1

UNC13B BAIAP3

9.87e-0471302IPR014770
DomainMHD1

UNC13B BAIAP3

9.87e-0471302PS51258
DomainDUF1041

UNC13B BAIAP3

9.87e-0471302PF06292
DomainCAPS_dom

UNC13B BAIAP3

9.87e-0471302IPR010439
DomainSpectrin_repeat

SYNE1 SPTBN2 UTRN

1.05e-03291303IPR002017
DomainCH

SYNE1 SPTBN2 MICALL1 UTRN

1.09e-03651304SM00033
DomainActin

ACTB ACTG1 ACTG2

1.28e-03311303IPR004000
DomainActin

ACTB ACTG1 ACTG2

1.28e-03311303PF00022
DomainACTIN

ACTB ACTG1 ACTG2

1.28e-03311303SM00268
Domain-

CPA4 CPA2

1.31e-03813023.30.70.340
DomainCullin_neddylation_domain

CUL9 CUL7

1.31e-0381302IPR019559
DomainCullin_Nedd8

CUL9 CUL7

1.31e-0381302PF10557
DomainCullin_Nedd8

CUL9 CUL7

1.31e-0381302SM00884
DomainPropep_M14

CPA4 CPA2

1.31e-0381302PF02244
DomainM14A_act_pep

CPA4 CPA2

1.31e-0381302IPR003146
DomainSPEC

SYNE1 SPTBN2 UTRN

1.41e-03321303SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN2 UTRN

1.41e-03321303IPR018159
DomainCH

SYNE1 SPTBN2 MICALL1 UTRN

1.44e-03701304PF00307
Domain-

SYNE1 SPTBN2 MICALL1 UTRN

1.52e-037113041.10.418.10
DomainCullin_homology

CUL9 CUL7

1.68e-0391302IPR016158
DomainCH

SYNE1 SPTBN2 MICALL1 UTRN

1.68e-03731304PS50021
DomainCH-domain

SYNE1 SPTBN2 MICALL1 UTRN

1.86e-03751304IPR001715
DomainMIR

RYR2 RYR3

2.09e-03101302PF02815
DomainMIR_motif

RYR2 RYR3

2.09e-03101302IPR016093
DomainCullin

CUL9 CUL7

2.09e-03101302PF00888
DomainMIR

RYR2 RYR3

2.09e-03101302PS50919
DomainMIR

RYR2 RYR3

2.09e-03101302SM00472
DomainCULLIN_2

CUL9 CUL7

2.09e-03101302PS50069
DomainCullin_N

CUL9 CUL7

2.09e-03101302IPR001373
DomainCULLIN_1

CUL9 CUL7

2.09e-03101302PS01256
DomainPNT

ETS2 ELF3

2.54e-03111302PS51433
DomainSAM_PNT

ETS2 ELF3

2.54e-03111302PF02198
DomainPointed_dom

ETS2 ELF3

2.54e-03111302IPR003118
DomainSAM_PNT

ETS2 ELF3

2.54e-03111302SM00251
DomainABC_A

ABCA3 ABCA4

3.03e-03121302IPR026082
DomainDynein_heavy_chain_D4_dom

DNAH3 DYNC2H1

4.14e-03141302IPR024317
DomainFN_type2_col-bd

PLA2R1 LY75

4.14e-03141302IPR000562
DomainFN2_2

PLA2R1 LY75

4.14e-03141302PS51092
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC2H1

4.14e-03141302IPR011704
DomainFN2_1

PLA2R1 LY75

4.14e-03141302PS00023
DomainAAA_8

DNAH3 DYNC2H1

4.14e-03141302PF12780
Domainfn2

PLA2R1 LY75

4.14e-03141302PF00040
DomainFN2

PLA2R1 LY75

4.14e-03141302SM00059
DomainAAA_5

DNAH3 DYNC2H1

4.14e-03141302PF07728
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN2 ACTB ACTG1

4.01e-05101003MM15112
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B DPYSL2 KIF1A TRPM7 SYNE1 SPTBN2 ACTB RAPGEF4 ETS2 CUL9 NCAM2 GRIK1 QRICH1 USP9Y TERF1 RYR3 IFT122 WDFY3 UTRN EXOC4

8.85e-0812851322035914814
Pubmed

HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.

TBX3 ETS2 TBX18 TBX5

2.62e-0715132425453830
Pubmed

Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.

TBX3 SFRP2 TBX18 TBX5

7.35e-0719132420185795
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTB ACTG1 ACTG2

1.06e-06613239971772
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTB ACTG1 ACTG2

1.06e-066132310074138
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTB ACTG1 ACTG2

1.06e-066132322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTB ACTG1 ACTG2

1.06e-06613231540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTB ACTG1 ACTG2

1.06e-066132311709093
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTB ACTG1 ACTG2

1.06e-066132310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTB ACTG1 ACTG2

1.06e-066132312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTB ACTG1 ACTG2

1.06e-066132323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTB ACTG1 ACTG2

1.06e-066132319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTB ACTG1 ACTG2

1.06e-066132321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTB ACTG1 ACTG2

1.06e-06613238661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTB ACTG1 ACTG2

1.06e-066132323017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTB ACTG1 ACTG2

1.06e-066132323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTB ACTG1 ACTG2

1.06e-06613239841925
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TBX3 NCAPD3 MPDZ BTAF1 TUBGCP4 PAPSS2 ZZEF1 DENND3 PARP4 RINT1 PLEKHA5 IFT122 EXOC4

1.27e-066501321338777146
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTB ACTG1 ACTG2

1.85e-067132322535526
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTB ACTG1 ACTG2

1.85e-067132318443296
Pubmed

Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis.

ACTG2 JAK2 SLC12A2

1.85e-067132312040017
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTB ACTG1 ACTG2

1.85e-067132322640593
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTB ACTG1 ACTG2

1.85e-067132317504171
Pubmed

The sinus venosus progenitors separate and diversify from the first and second heart fields early in development.

TBX3 TBX18 TBX5

1.85e-067132320110338
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTB ACTG1 ACTG2

1.85e-067132322465675
Pubmed

Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.

TBX3 RYR2 TBX18 TBX5

1.99e-0624132434062094
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTB ACTG1 ACTG2

2.95e-068132314694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTB ACTG1 ACTG2

2.95e-068132320147394
Pubmed

A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family.

TBX15 TBX3 TBX5

2.95e-06813239503012
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTB ACTG1 ACTG2

2.95e-068132323260110
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTB ACTG1 ACTG2

4.41e-069132310556093
Pubmed

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

SFRP2 SPTBN2 ACTB

4.41e-069132311357136
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTB ACTG1 ACTG2

4.41e-06913238892894
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTB ACTG1 ACTG2

4.41e-069132318775311
Pubmed

Wnt/β-catenin signaling maintains the mesenchymal precursor pool for murine sinus horn formation.

TBX3 SFRP2 TBX18 TBX5

5.76e-0631132421757651
Pubmed

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.

TBX3 RYR2 TBX5

6.29e-0610132332672536
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTB ACTG1 ACTG2

6.29e-061013231907279
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTB ACTG1 ACTG2

6.29e-061013231991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTB ACTG1 ACTG2

6.29e-0610132323575248
Pubmed

SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart.

SFRP2 RYR2 BPGM

6.29e-0610132319386262
Pubmed

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.

TBX15 TBX3 TBX18 TBX5

7.45e-0633132418356246
Pubmed

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.

TBX3 TBX18 TBX5

8.62e-0611132317668378
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTB ACTG1 ACTG2

8.62e-0611132330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTB ACTG1 ACTG2

8.62e-0611132323294842
Pubmed

Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

SV2A SV2C UTRN

8.62e-0611132312403715
Pubmed

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.

TBX15 TBX18 TBX5

8.62e-0611132317584735
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTB ACTG1 ACTG2

8.62e-0611132319639585
Pubmed

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

ACTB ACTG1 ACTG2 MNT

9.47e-0635132420946988
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTB ACTG1 ACTG2

1.15e-0512132323071112
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ARHGAP32 COL17A1 RHBDF1 TRPM7 LEMD3 MARK3 SPTBN2 MICALL1 KLHL38 SLC12A2 PLEKHA5

1.19e-055691321130639242
Pubmed

Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.

ACTB ACTG1

1.43e-052132221778137
Pubmed

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.

ACTB ACTG1

1.43e-052132222366783
Pubmed

Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.

ACTB ACTG1

1.43e-052132232588558
Pubmed

A novel brain-specific isoform of beta spectrin: isolation and its interaction with Munc13.

UNC13B SPTBN2

1.43e-05213229704016
Pubmed

Association of the ACE I/D gene polymorphisms with JAK2V617F-positive polycythemia vera and essential thrombocythemia.

ACE JAK2

1.43e-052132225955555
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome.

ACTB ACTG1

1.43e-052132227625340
Pubmed

New insights on cellular distribution, microtubule interactions and post-translational modifications of MS-KIF18A.

KIF18A ACTB

1.43e-052132218680169
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.43e-05213228898078
Pubmed

Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.

ACTB ACTG1

1.43e-05213223221869
Pubmed

Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation.

JAK2 AURKA

1.43e-052132224930769
Pubmed

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.

SYNE1 CSMD1

1.43e-052132224387768
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.43e-052132214550562
Pubmed

Identification and developmental expression of a smooth-muscle gamma-actin in postmeiotic male germ cells of mice.

ACTG1 ACTG2

1.43e-05213222747639
Pubmed

Identification of a novel percent mammographic density locus at 12q24.

TBX3 TBX5

1.43e-052132222532574
Pubmed

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.

ACTB ACTG1

1.43e-052132221502360
Pubmed

The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.

ACTB ACTG1

1.43e-05213226686106
Pubmed

Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.

ACTB ACTG1

1.43e-0521322213279
Pubmed

The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.

ACTB ACTG1

1.43e-052132233334799
Pubmed

β-Actin specifically controls cell growth, migration, and the G-actin pool.

ACTB ACTG1

1.43e-052132221900491
Pubmed

Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.

ACTB ACTG1

1.43e-052132219638415
Pubmed

Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.

ACTB ACTG1

1.43e-05213223335520
Pubmed

Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

ACTB ACTG1

1.43e-05213229288906
Pubmed

High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.

ACTB ACTG1

1.43e-05213221577857
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.43e-052132221531043
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

1.43e-05213228026587
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.43e-052132216678258
Pubmed

Baraitser-Winter Cerebrofrontofacial Syndrome

ACTB ACTG1

1.43e-052132226583190
Pubmed

Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.

ACTB ACTG1

1.43e-052132232326615
Pubmed

Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.

ACTB ACTG1

1.43e-052132223756437
Pubmed

Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.

ACTB ACTG1

1.43e-05213228482333
Pubmed

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.

ACTB ACTG1

1.43e-052132229265728
Pubmed

Murine Brca2: sequence, map position, and expression pattern.

ACTB BRCA2

1.43e-05213229119389
Pubmed

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

ACTB ACTG1

1.43e-052132222246323
Pubmed

AURKA and BRCA2 expression highly correlate with prognosis of endometrioid ovarian carcinoma.

AURKA BRCA2

1.43e-052132221441901
Pubmed

Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.

ACTB ACTG1

1.43e-05213222837653
Pubmed

Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.

ACTB ACTG1

1.43e-052132232349449
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.

ACTB ACTG1

1.43e-052132232506774
Pubmed

TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression.

TERF1 AURKA

1.43e-052132220160025
Pubmed

Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.

ACTB ACTG1

1.43e-052132220847274
Pubmed

[Role of over-expression of TBX3 and TBX18 in the enrichment and differentiation of human induced pluripotent stem cells into sinoatrial node-like cells].

TBX3 TBX18

1.43e-052132230983202
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

1.43e-052132214985349
Pubmed

TBX3 and TBX5 duplication: A family with an atypical overlapping Holt-Oram/ulnar-mammary syndrome phenotype.

TBX3 TBX5

1.43e-052132233930582
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

ARHGAP32 RHBDF1 TRPM7 LEMD3 MARK3 MICALL1 SLC12A2 PLEKHA5 UTRN

1.48e-05377132938117590
Pubmed

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.

MPDZ CUL9 CUL7

1.89e-0514132322653443
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

ACTB ACTG1 ACTG2

1.89e-0514132321923909
Pubmed

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.

TBX3 TBX18 TBX5

1.89e-0514132318467625
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTB ACTG1 ACTG2

1.89e-0514132317411366
Pubmed

Identification of a novel actin isoform in hepatocellular carcinoma.

ACTB ACTG1 ACTG2

2.35e-0515132316824795
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B MARK3 SYNE1 CUL9 SV2A BTBD7 ANKRD12 SUZ12 BAIAP3

2.69e-05407132912693553
Pubmed

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.

NCAM2 SV2A SV2C

2.89e-0516132317715346
InteractionCTNNA1 interactions

CPA4 ARHGAP32 SFRP2 MARK3 ACTB ACTG1 CUL7 RRM1 RINT1 PLEKHA5 SUZ12 UTRN

3.08e-0634713212int:CTNNA1
GeneFamilyT-boxes

TBX15 TBX3 TBX18 TBX5

2.75e-06181024766
GeneFamilyActins

ACTB ACTG1 ACTG2

3.44e-0661023929
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

9.42e-0531022287
GeneFamilyCullins

CUL9 CUL7

8.63e-04810221032
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500

KIF18A TBX3 SCHIP1 SFRP2 SYNE1 ACTB ACTG2 RYR3 MICALL1 TBX18 CHSY3 SUZ12

5.99e-0639313112gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000

MAOB ETFBKMT CPA2 RNF43 RYR2 PLA2R1 CYP4F3 KLHL8 LY75 TAFAZZIN

9.91e-0628113110gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

KIF18A TBX3 SFRP2 COL17A1 GPBP1 TRPM7 RAPGEF4 ACTG2 RRM1 RYR2 MICALL1 TBX18 CERS3 PLEKHA5 CHSY3 UTRN TBX5

1.05e-0581113117gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200

TBX15 TBX3 COL17A1 TMEM132C TBX18 CERS3 CHSY3 TBX5

1.33e-051751318gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_100

TBX15 COL17A1 TMEM132C CERS3 CHSY3 TBX5

2.27e-05921316gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBX3 ETS2 SRM RNF43 ADAM28 TMEM132C LIPG TBX5

1.21e-071941328fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 SYNE1 MPDZ CFAP221 PLEKHA5 ELF3 CFAP46

1.25e-071951328fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 SYNE1 MPDZ CFAP221 PLEKHA5 ELF3 CFAP46

1.25e-071951328eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBX3 ACTB ETS2 RNF43 ADAM28 TMEM132C TBX5

1.80e-061931327e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellIPF-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

UNC13B TBX3 SYNE1 PAPSS2 ACE BPGM SLC12A2

1.86e-061941327777ce41c3f22c591e2d81120f189b834e53ffb4b
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 MPDZ CFAP221 PLEKHA5 ELF3 CFAP46

1.92e-06195132721dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TEKT3 DNAH3 DYNC2H1 SYNE1 MPDZ CFAP221 CFAP46

2.06e-06197132774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellCOVID-19_Severe-Neu_2|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

COL17A1 SYNE1 ACTB ACTG1 CYP4F3 TESC TAFAZZIN

2.06e-061971327945f19475905cdedf232315eea1076ca0b753b67
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

UNC13B TBX3 DDX60 SMCHD1 ETS2 ACE SLC12A2

2.28e-062001327be55cef682ba87250dad97689332c8820b3a7420
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX3 SYNE1 NCAM2 RYR2 TMEM132C CHSY3 TBX5

2.28e-06200132758b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

TBX3 RHBDF1 SYNE1 ACE SLC12A2 BAIAP3

7.48e-06157132684f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 TMEM132C IL1RAPL2 BAIAP3 UTRN CFAP46

7.48e-061571326741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SMCHD1 USP9Y ATP8B2 ANKRD12 UTRN EXOC4

8.94e-061621326b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 AOC2 TLR8 LIPG KLHL8 TBX5

1.03e-051661326aa2df07eff323ded751ced8938af08223d7f2029
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 AOC2 TLR8 LIPG KLHL8 TBX5

1.03e-051661326695298a94d62b8adab083900003ec636fbaae5d9
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TEKT3 DNAH3 DYNC2H1 CFAP221 FTO CFAP46

1.14e-051691326fba841664939c771881ba97f14ef1df6635c04ff
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SFRP2 GRIK1 TMEM132C BAIAP3 CFAP46

1.27e-051011325cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPSS2 RYR3 PLA2R1 SYDE2 CFAP221 UTRN

1.34e-051741326ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TBX3 HSPB3 MAOB ACTG2 SEZ6 TBX5

1.39e-051751326ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH3 SRM PRELID3B NCAM2 ATP8B2 CHSY3

1.39e-0517513269a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH3 SRM PRELID3B NCAM2 ATP8B2 CHSY3

1.39e-05175132654c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH3 SRM PRELID3B NCAM2 ATP8B2 CHSY3

1.39e-0517513262b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCHIP1 HSPB3 GRIK1 IL1RAPL2 BHMT2 CSMD1

1.48e-051771326b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 MPDZ CFAP221 BAIAP3 CFAP46

1.96e-05186132676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPB3 SYNE1 ACTG2 RYR2 TMEM132C TBX5

2.08e-0518813263177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

GPBP1 TRPM7 SMCHD1 BTAF1 ANKRD12 UTRN

2.08e-051881326ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

UNC13B TBX3 SYNE1 PAPSS2 ACE SLC12A2

2.08e-05188132688b3415e33db81726dd29c1f50c886e057af50a0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

UNC13B ERCC3 ACTB ACTG1 ACTG2 RYR3

2.14e-0518913263717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

DNAH3 RYR3 CFAP221 ELF3 BAIAP3 CFAP46

2.27e-051911326ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL17A1 SYNE1 ACTB DENND3 CYP4F3 WDFY3

2.27e-051911326d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

DNAH3 RYR3 CFAP221 ELF3 BAIAP3 CFAP46

2.27e-0519113266228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBX3 ETS2 SRM ADAM28 TMEM132C TBX5

2.34e-0519213264c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 SMCHD1 BTAF1 USP9Y ANKRD12 UTRN

2.41e-0519313269337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UNC13B ABCA3 DYNC2H1 SYNE1 CFAP221 CFAP46

2.41e-051931326bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 SYNE1 CFAP221 BAIAP3 CFAP46

2.55e-0519513263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

KIF18A DPYSL2 GPAA1 LEMD3 AURKA ARSD

2.63e-051961326b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 RAPGEF4 RYR2 PLEKHA5 CHSY3 CSMD1

2.63e-051961326676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 MPDZ CFAP221 ELF3 CFAP46

2.63e-051961326af4cdc61830685a888a1209826c23bcf54a43084
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAOB CPA2 RNF43 SLC12A2 UGT2A3 ELF3

2.63e-0519613264deaadb9796b907b7480fb7af5ed76ebad240850
ToppCellCOVID-19_Severe-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

COL17A1 SYNE1 ACTB ACTG1 CYP4F3 TESC

2.63e-05196132616359a56297f0558fc93fa52563cce0c53def167
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 MPDZ CFAP221 ELF3 CFAP46

2.63e-0519613266d02d494196e3f857d53eea46d9419690d43beca
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 CFAP221 PLEKHA5 ELF3 CFAP46

2.63e-05196132687d9881cfec461a5d89b688a83749b618c519485
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

UNC13B ARHGAP32 ABCA3 RNF43 ELF3 UTRN

2.70e-05197132644a59dfb889577b3160a5b13ada1276771a00241
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAOB CPA2 RNF43 SLC12A2 UGT2A3 ELF3

2.70e-051971326f097e729f515e7945b9482e9f9dbc9536b90f0bb
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GPBP1 DDX60 SYNE1 SMCHD1 ACTB ACTG1

2.78e-0519813268165ff735095c52994fb5057d89be93cc378b7da
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 RAPGEF4 RYR2 PLEKHA5 CHSY3 CSMD1

2.78e-0519813266d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 RAPGEF4 RYR2 PLEKHA5 CHSY3 CSMD1

2.78e-0519813264ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 SMCHD1 BTAF1 USP9Y ANKRD12 UTRN

2.86e-051991326f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

KIF18A NCAPD3 RRM1 AURKA BRCA2 TESC

2.86e-05199132647c47ebc318a0b98841ca2656837bbd068899559
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TBX3 HSPB3 ACTB ACTG2 TERF1 RYR3

2.86e-051991326a207b4891881149d4c50721310690fd794157723
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

KIF18A NCAPD3 RRM1 AURKA BRCA2 TESC

2.86e-051991326c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCHIP1 MAOB KIF1A LIPG SYDE2 SV2C

2.86e-0519913262b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAOB ACTG2 CUL9 RINT1 BRCA2 ZNF85

2.86e-0519913266e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAOB ACTG2 CUL9 RINT1 BRCA2 ZNF85

2.86e-0519913265f499595597c10857bba8272f62afe4d32d733ac
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

COL17A1 SYNE1 ACTB BRCA2 CYP4F3 TESC

2.94e-052001326cbe667eda1af222467df8bfa157aa22df488f133
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ADAM28 PLA2R1 SLC12A2 PLEKHA5 ELF3

2.94e-052001326682960e28542a3d6c119047cd0131941932cfdea
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SYNE1 RAPGEF4 RYR2 PLEKHA5 CHSY3 CSMD1

2.94e-05200132648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DDX60 SMCHD1 RAPGEF4 ETS2 ACE SLC12A2

2.94e-05200132689821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

HSPB3 SYNE1 ACTG2 RYR2 LIPG TBX5

2.94e-0520013265ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DDX60 SMCHD1 BTAF1 JAK2 ANKRD12 UTRN

2.94e-05200132612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

CPAMD8 SCHIP1 ADA2 ARSD SYDE2 SERTAD3

2.94e-0520013266b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HSPB3 SYNE1 ACTG2 RYR2 LIPG TBX5

2.94e-05200132667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

SYNE1 ACTG2 RYR2 LIPG CSMD1 TBX5

2.94e-0520013268c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MAOB DYNC2H1 PAPSS2 RYR2 TMEM132C TBX5

2.94e-052001326a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAOB CYP4F2 UGT2A3 BHMT2 CYP4F3 PCK1

2.94e-052001326825aad08431dd6b54aa636ace6efc821dfaf8014
ToppCell21-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

SPTBN2 NCAM2 TLR8 TIGD6 SV2C

4.97e-0513413254f0465324cc5b443ebadb68aef63be79b74f6ff9
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

DYNC2H1 SYNE1 RAPGEF4 BTAF1 PLEKHA5

5.15e-051351325ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SFRP2 GRIK1 TMEM132C IL1RAPL2 CFAP46

7.22e-0514513258b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 UGT2A3 PCK1

8.75e-051511325cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 UGT2A3 PCK1

8.75e-0515113257758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TBX15 ACTG2 TBX18 PLA2R1 LIPG

8.75e-051511325527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCellFrontal_cortex-Endothelial-MURAL|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TBX15 ACTG2 TBX18 PLA2R1 LIPG

8.75e-0515113257570372a315bc312ff57bb5f483375c401ae8787
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 UGT2A3 PCK1

8.75e-051511325b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 UGT2A3 PCK1

9.02e-0515213251febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 UGT2A3 PCK1

9.02e-051521325faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TBX15 RAPGEF4 GRIK1 RYR3 TBX5

9.60e-051541325df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TBX3 ACTG2 RNF43 TMEM132C TBX5

1.05e-041571325b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 RAPGEF4 BRCA2 IFT122 CFAP46

1.05e-041571325410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

DNAH3 SFRP2 HSPB3 MAOB SPTBN2

1.08e-041581325ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 NCAM2 RYR2 SV2C CSMD1

1.12e-0415913255335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPB3 ACTG2 ZNF85 BAIAP3 TBX5

1.12e-0415913257cda111bb98f1241989e49d490bdf51a712ea589
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.15e-0416013258de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCelldroplet-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.25e-041631325a794540f2d8984f963c08f05175e4bc916fcc224
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.25e-04163132503d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.25e-0416313251c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.25e-0416313257e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCelldroplet-Liver-Hepatocytes-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB APOA5 PAPSS2 BHMT2 PCK1

1.29e-041641325c9866a289e120be4066e66275c3beb97ba67cca4
ToppCell5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN2 RRM1 RNF43 TGM4 SLC12A2

1.29e-04164132529da0175bd3808a5b3039a6161c764105608ef96
ToppCell5'-Adult-Appendix-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN2 RRM1 RNF43 TGM4 SLC12A2

1.29e-041641325e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PAPSS2 UGT2A3 BHMT2 PCK1

1.29e-04164132590afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e-Excitatory_Neuron.Sc17a7.Sema3e-Nnat_(Layer_6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EFCAB3 IL1RAPL2 LIPG TESC

1.30e-048713247518ca56d626619d9706505169a85f1850105608
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC3 DDX60 DENND3 AURKA KLHL8

1.33e-0416513251d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

SWT1 RAPGEF4 RYR2 PLA2R1 BHMT2

1.36e-0416613257286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PAPSS2 UGT2A3 BHMT2 PCK1

1.36e-0416613254b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

SWT1 RAPGEF4 RYR2 PLA2R1 BHMT2

1.36e-0416613257c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PAPSS2 UGT2A3 BHMT2 PCK1

1.36e-041661325d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX18 BPGM LIPG ZFP82 TBX5

1.48e-0416913252d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX18 BPGM LIPG ZFP82 TBX5

1.48e-041691325ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC12A2 IL1RAPL2 SV2C TESC CFAP46

1.48e-041691325a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX18 BPGM LIPG ZFP82 TBX5

1.48e-041691325ad6af6609acf158cb79e45ee7ca9af332be3c40c
Drugplakin

COL17A1 SYNE1 SPTBN2 ACTB ACTG1 ACTG2 UTRN

4.97e-07821327CID000018752
DrugAC1N9ZZC

UNC13B DPYSL2 KIF1A ACTG1 NCAM2 RYR2 RYR3 PCK1

2.59e-061491328CID004369374
DrugNpCaM

CPA4 ACTB ACTG1 ACTG2 CPA2

8.51e-06481325CID000122259
DrugBoc-ca-phe

CPA4 CPA2 ACE

1.04e-0581323CID005487215
DrugZ-ca-gly-phe

CPA4 CPA2 ACE

1.04e-0581323CID000195338
Drughippuryl-histidyl-leucine

CPA4 CPA2 ACE SLC12A2

1.46e-05261324CID000094418
Drugfoscarnet

COL17A1 ACTB ACTG1 ACTG2 RRM1 TLR8 POLR3E PCK1

1.55e-051901328CID000003414
DrugMuracein A

CPA4 CPA2 ACE

1.56e-0591323CID005491013
Drugmanidipine

ACTB ACTG1 ACTG2 ACE RYR2 RYR3

1.93e-05951326CID000004008
DiseaseMoyamoya disease (implicated_via_orthology)

ACTB ACTG1 ACTG2

4.82e-0681323DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTB ACTG1 ACTG2

4.82e-0681323DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTB ACTG1 ACTG2

4.82e-0681323DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTB ACTG1 ACTG2

4.82e-0681323DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTB ACTG1 ACTG2

1.03e-05101323DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTB ACTG1 ACTG2

1.03e-05101323DOID:13832 (implicated_via_orthology)
DiseaseColorectal Carcinoma

UNC13B DNAH3 CPAMD8 DPYSL2 ABCA3 SFRP2 ABCA4 TRPM7 SYNE1 SPTBN2 RNF43 AURKA EXOC4

1.69e-0570213213C0009402
DiseaseBaraitser-Winter syndrome

ACTB ACTG1

1.99e-0521322cv:C1853623
Diseasecarboxypeptidase A4 measurement

CPA4 CPA2

1.99e-0521322EFO_0801452
DiseaseIris Coloboma with Ptosis, Hypertelorism, and Mental Retardation

ACTB ACTG1

1.99e-0521322C1855722
DiseaseFryns-Aftimos Syndrome

ACTB ACTG1

1.99e-0521322C1853623
DiseaseColorectal Neoplasms

CPAMD8 ABCA3 SFRP2 ABCA4 TRPM7 SYNE1 RNF43 AURKA

3.68e-052771328C0009404
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

5.94e-0531322DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

5.94e-0531322DOID:8545 (implicated_via_orthology)
Diseasesecretory phospholipase A2 receptor measurement

PLA2R1 LY75

5.94e-0531322EFO_0802043
DiseaseInfantile Obesity

APOA5 FTO

1.18e-0441322C4553478
DiseaseChildhood Overweight

APOA5 FTO

1.18e-0441322C4521075
DiseasePediatric Obesity

APOA5 FTO

1.18e-0441322C2362324
DiseaseAdolescent Overweight

APOA5 FTO

1.18e-0441322C4704956
DiseaseInfant Overweight

APOA5 FTO

1.18e-0441322C4704955
DiseaseAdolescent Obesity

APOA5 FTO

1.18e-0441322C4317171
Diseaselung carcinoma (is_marker_for)

ACE JAK2

1.97e-0451322DOID:3905 (is_marker_for)
Diseasecerebral infarction (is_implicated_in)

APOA5 ACE LIPG

2.94e-04291323DOID:3526 (is_implicated_in)
DiseaseMalignant neoplasm of breast

TBX3 ABCA3 SFRP2 ERCC3 ABCA4 WDR88 DYNC2H1 SYNE1 ETS2 MICALL1 AURKA BRCA2 IL1RAPL2 FTO

3.34e-04107413214C0006142
DiseaseDisproportionate short stature

DYNC2H1 CUL7 PAPSS2 IFT122

4.02e-04771324C0878659
DiseaseUveoretinal Coloboma

ACTB ACTG1

4.11e-0471322C4554007
DiseaseMASA syndrome (implicated_via_orthology)

TRPM7 TRPM1

4.11e-0471322DOID:0060246 (implicated_via_orthology)
DiseaseAbnormality of radial ray

TBX3 BRCA2 TBX5

4.33e-04331323C4228778
Diseasestomach cancer (is_marker_for)

KIF18A TBX3 TERF1 RNF43 JAK2

4.56e-041421325DOID:10534 (is_marker_for)
DiseaseStuttering

HSPB3 RHBDF1 DENND3 RYR2 PLEKHA5

4.71e-041431325HP_0025268
Diseasecortical thickness

CPA4 CPAMD8 DPYSL2 ABCA4 MARK3 SPTBN2 CUL9 DENND3 MICALL1 KLHL38 BPGM TESC KLHL8 EXOC4

4.77e-04111313214EFO_0004840
DiseaseCraniofacial Abnormalities

TBX15 ACTB ETS2 ACTG1 MNT

6.98e-041561325C0376634
DiseaseCongenital ocular coloboma (disorder)

ACTB ACTG1

7.00e-0491322C0009363
Diseaseliver cancer (is_marker_for)

ADAM28 JAK2

7.00e-0491322DOID:3571 (is_marker_for)
DiseaseCleft upper lip

ABCA4 BHMT2 PLEKHA5

7.11e-04391323C0008924
Diseasecolorectal cancer (is_marker_for)

KIF18A TBX3 ERCC3 ADAM28 BRCA2

7.19e-041571325DOID:9256 (is_marker_for)
DiseaseCongenital neurologic anomalies

ACTB ACTG1

8.73e-04101322C0497552
DiseaseCranioschisis

ACTB ACTG1

8.73e-04101322C0265541
Diseasechronic obstructive pulmonary disease, chronic bronchitis

CFAP221 CSMD1

8.73e-04101322EFO_0000341, EFO_0006505
Diseasecoronary artery disease (is_implicated_in)

APOA5 ACE LIPG FTO

1.08e-031001324DOID:3393 (is_implicated_in)
Diseasevenous thromboembolism

ERCC3 LEMD3 NCAM2 FASTKD2 NLRP2 TGM4 SV2C TBX5

1.12e-034601328EFO_0004286
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

LEMD3 SYNE1

1.27e-03121322DOID:11726 (implicated_via_orthology)
DiseaseAlcoholic Intoxication, Chronic

DPYSL2 MAOB MPDZ GRIK1 ACE FTO

1.34e-032681326C0001973
Diseaselung adenocarcinoma (is_implicated_in)

RNF43 ADAM28 JAK2

1.39e-03491323DOID:3910 (is_implicated_in)
DiseaseBipolar Disorder

DPYSL2 MAOB SYNE1 ACTB GRIK1 ACE BRCA2 CSMD1

1.41e-034771328C0005586
DiseaseBenign tumor of pancreas

RNF43 BRCA2

1.50e-03131322C0347284
Diseaseleukemia (is_implicated_in)

ACE JAK2

1.50e-03131322DOID:1240 (is_implicated_in)
Diseasechromosome-type aberration frequency

SUZ12 FTO

1.74e-03141322EFO_0009861
DiseaseSchizophrenia

ARHGAP32 MAOB SPTBN2 ACTB GRIK1 ACE SLC12A2 SV2A TRPM1 CSMD1 PCK1

2.10e-0388313211C0036341
DiseaseMammary Carcinoma, Human

TBX3 SFRP2 DYNC2H1 SYNE1 ETS2 AURKA BRCA2 FTO

2.56e-035251328C4704874
DiseaseMammary Neoplasms, Human

TBX3 SFRP2 DYNC2H1 SYNE1 ETS2 AURKA BRCA2 FTO

2.56e-035251328C1257931
DiseaseMammary Neoplasms

TBX3 SFRP2 DYNC2H1 SYNE1 ETS2 AURKA BRCA2 FTO

2.62e-035271328C1458155
DiseaseBreast Carcinoma

TBX3 SFRP2 DYNC2H1 SYNE1 ETS2 AURKA BRCA2 FTO

2.97e-035381328C0678222
DiseasePancreatic carcinoma

RNF43 BRCA2

3.23e-03191322C0235974
Diseaseankylosing spondylitis (is_implicated_in)

ACE JAK2

3.23e-03191322DOID:7147 (is_implicated_in)
Diseasemyocardial infarction (implicated_via_orthology)

ACE JAK2 TBX5

3.26e-03661323DOID:5844 (implicated_via_orthology)
DiseaseAdenocarcinoma of prostate

AURKA BRCA2

3.58e-03201322C0007112
Diseaselung cancer

GRIK1 CSMD1

3.94e-03211322MONDO_0008903
Diseasecardiovascular system disease (is_implicated_in)

LIPG FTO

3.94e-03211322DOID:1287 (is_implicated_in)
Diseasesevere acute respiratory syndrome, COVID-19

ACTB NCAM2 MICALL1 TMEM132C CHSY3 TRPM1 CSMD1

4.07e-034471327EFO_0000694, MONDO_0100096
Diseasevitamin D measurement

APOA5 LIPG UGT2A3 KLHL8 FTO EXOC4

4.11e-033361326EFO_0004631
Diseasetemporal horn of lateral ventricle volume measurement

RAPGEF4 CSMD1 UTRN

4.17e-03721323EFO_0010333
Diseaseblood pressure

SYNE1 EXOC4

4.33e-03221322EFO_0004325
Diseasetriacylglycerol 58:9 measurement

FASTKD2 CSMD1

4.33e-03221322EFO_0010443

Protein segments in the cluster

PeptideGeneStartEntry
DKIGLHSDSQEELWM

COL17A1

536

Q9UMD9
VEEMDWLIGKVLNAI

ARSD

326

P51689
IEGRMHDEKVDLWSL

AURKA

301

O14965
IVFDTEMAHDILKVW

CSMD1

1321

Q96PZ7
EMAHDILKVWDGPVD

CSMD1

1326

Q96PZ7
HWDLIGKNLFAMVVE

ABCA4

1871

P78363
WQEVLKDMVGLDALD

ACE

581

P12821
NTHVALVGMEIWTDK

ADAM28

246

Q9UKQ2
LLGLLEDMQAHWEEA

BAIAP3

476

O94812
IEHGIVTNWDDMEKI

ACTB

71

P60709
IEHGIVTNWDDMEKI

ACTG1

71

P63261
MNLIKEARWDGLTGH

GRIK1

361

P39086
GEWNGMVKELIDHRA

GRIK1

511

P39086
QMLWNRLHKEETEGG

CFAP46

2361

Q8IYW2
KQMLHIIGLEDKWNS

ABCA3

646

Q99758
PIEHGIITNWDDMEK

ACTG2

71

P63267
EETWLGLKAIMEHVR

CPA2

401

P48052
MAEAHELVGWNLEGL

APOA5

111

Q6Q788
DILIHPELNEGLMKW

ELF3

281

P78545
PELNEGLMKWENRHE

ELF3

286

P78545
ERNMLERGEAEWHKL

CCDC144CP

996

Q8IYA2
CWELKGNMVVLVHDS

ELP6

171

Q0PNE2
DLNKIALEWVAIMHG

DNHD1

1236

Q96M86
ERMLSLKDLEIEQWH

ANKRD12

1081

Q6UB98
VSLPWLVMEHLDKNE

DENND3

706

A2RUS2
MGVILAIGNAIWEHE

ATP8B2

306

P98198
KEEGWLAEHMLILGI

PCK1

256

P35558
SHVTEEMLWECKQLG

QRICH1

601

Q2TAL8
LEVAKQLAWAMHFLE

JAK2

651

O60674
MEIGDQWHLAIQEAI

LEMD3

796

Q9Y2U8
EFTQMWRHLKEVELP

AOC2

171

O75106
LHAMGKIPEDEIWQS

MAOB

451

P27338
DWRMKQHAAVLEEGV

PAPSS2

456

O95340
DHGWVDMLIDIARKL

IFT122

786

Q9HBG6
GLKALELWMQLHEAG

GPAA1

386

O43292
ISEWHKGIQEEMEAL

DPYSL2

141

Q16555
SLEAEHRLLKEMGWQ

GPBP1

381

Q86WP2
LWKKMEGVTNAVLHE

FTO

406

Q9C0B1
WLHRVEKEMGLLSQN

KIF18A

511

Q8NI77
GEIGAEIWEHLLVMI

DDX60

896

Q8IY21
EGWLLIKAQHGTRMD

HSPB3

91

Q12988
WMEIANKLPQLIDAH

IDO2

56

Q6ZQW0
DPHLDKWIEVKEMGQ

KLHL8

481

Q9P2G9
GQVDCKAEHILLWMS

CUL7

56

Q14999
GDILWEHLEQMIKEN

ETS2

156

P15036
VGHSIARMLDWLQEK

LIPG

141

Q9Y5X9
KLHNEDIKEEVWIGL

LY75

411

O60449
LAELKHELSQWMDVL

MNT

296

Q99583
GREDDMLVDWFKLIH

MICALL1

716

Q8N3F8
VAEHLWKLMVEESDL

TUBGCP4

336

Q9UGJ1
LMLDWAEDNLIHKFK

NLRP2

226

Q9NX02
LIMLRHGEGAWNKEN

BPGM

6

P07738
LVEMIWAEALGHLEH

PARP4

266

Q9UKK3
LTWMEIDNKGNHLLV

ARHGAP32

236

A7KAX9
QHKEWIVIGQVDMEA

DYNC2H1

856

Q8NCM8
DLKALANMHESLEWL

EXOC4

706

Q96A65
GTLVMIVHDVADIWL

CERS3

231

Q8IU89
IVHDVADIWLESAKM

CERS3

236

Q8IU89
LMKEGLEWAGLKAHL

BHMT2

221

Q9H2M3
WIDLNEDIIKPHMLI

BRCA2

3106

P51587
SQEILDLIHKVWMEL

BTAF1

576

O14981
MEHLEQNLGEWKLIY

DNAH3

3436

Q8TD57
WLGLKTIMEHVRDNL

CPA4

406

Q9UI42
AQHVWLETKVMALNG

CPAMD8

416

Q8IZJ3
LHLHDIGIVTMDWLV

ADA2

111

Q9NZK5
VNIMHAKWQLLASEG

CYP4F2

171

P78329
DHAKQMRELLSGWDV

BTBD7

81

Q9P203
IMKDRWINAGHEEDE

MARK3

301

P27448
EEGKAEHILMWLSAP

CUL9

56

Q8IWT3
VNIMHAKWQLLASEG

CYP4F3

171

Q08477
KTQEWGLMILDEVHT

ERCC3

431

P19447
LEQDKWDLVVLGDMF

ETFBKMT

176

Q8IXQ9
GIALEHRKEMLNLWQ

EFCAB3

341

Q8N7B9
IREKLAENIHELWVM

RYR2

881

Q92736
AENIHELWVMNKIEL

RYR2

886

Q92736
LEHMAVVRINKGWEF

POLR3E

386

Q9NVU0
LLMTHGVLEEWDVKR

NSMCE1

21

Q8WV22
ILLQAASDKDMHDWL

KIF1A

1651

Q12756
EMENHLKWQVHLGKD

CFAP221

371

Q4G0U5
MHSWIKEIGAAVQAL

PLEKHA2

286

Q9HB19
KVTLMEQWENSLHGL

SYDE2

791

Q5VT97
PEISVKEFIDWMHLE

UTRN

3031

P46939
MWQVLLEDGVLNHVD

RAPGEF4

261

Q8WZA2
HETMKEVLEQAGAWI

SFRP2

66

Q96HF1
LMNGLGIDKINEWHA

TIGD6

146

Q17RP2
GREAMEWVIHKLNAE

PRELID3B

156

Q9Y3B1
DEVNWIAGDIMHNLI

SMCHD1

1056

A6NHR9
FLLEVGKHDEAWMIL

SV2C

346

Q496J9
GKHDEAWMILKLIHD

SV2C

351

Q496J9
ELWDQFHKRGTEMVI

TBX3

111

O15119
WANLDHMVGQLKILL

SYNE1

7111

Q8NF91
KVQVLFHIMGRDWDD

TMEM132C

146

Q8N3T6
MEGIKVFLHERELWL

TBX5

51

Q99593
RELWLKFHEVGTEMI

TBX5

61

Q99593
PMDWEALEKHLAGLQ

SCHIP1

221

P0DPB3
WMKGEKFIEELAGHI

IL1RAPL2

281

Q9NP60
GFHVILVNNWEMDKL

FASTKD2

666

Q9NYY8
DLWKRFHDIGTEMII

TBX15

121

Q96SF7
QMTVLRDLEKLAGWH

RHBDF1

676

Q96CC6
VVLIWGNDAEKLMEF

RNF43

161

Q68DV7
WKSEIIHELDEMIGE

TEKT3

156

Q9BXF9
WLVKMVNGQEELHVI

TGM4

396

P49221
HWLAVFGLVMEKNLL

SWT1

631

Q5T5J6
KTVEVWMGLNQLDEH

PLA2R1

286

Q13018
FLENGKHDEAWMVLK

SV2A

361

Q7L0J3
WEWNELDHIMEIILG

SERTAD3

181

Q9UJW9
TMQLAELWLEKHLGV

CHSY3

861

Q70JA7
HCDVSGMKEDLWILQ

NCAPD3

571

P42695
WQGIDIETKMHVRFL

TESC

191

Q96BS2
WMDEHLNVKIPRLVD

TLR8

786

Q9NR97
AELIKQMWSGRDAHV

USP4

356

Q13107
KLSLKGHNDWVMDVA

WDR88

356

Q6ZMY6
ELIIEGQWHHLVLVM

WDFY3

1186

Q8IZQ1
LAMWEAGIQHIELEK

MPDZ

691

O75970
GNKDHIILEHLQWTM

NCAM2

646

O15394
IKLSQDFMILWLHGE

NHLRC3

191

Q5JS37
PELAELQEMWKRLGH

SPTBN2

1561

O15020
GMDFILEKLNHGDWV

TAFAZZIN

131

Q16635
LMWIGNHTEFLDEKI

RINT1

341

Q6NUQ1
LLKDLTERGLWHEEM

RRM1

641

P23921
MAHLELLLVENFKSW

SMC1B

1

Q8NDV3
AELWKRFHEIGTEMI

TBX18

146

O95935
RLAENIHELWGMNKI

RYR3

871

Q15413
VNEGEKEVMKLWNLH

SUZ12

606

Q15022
AGMEWEAKAQIVLLV

SLC12A2

426

P55011
WGVHVEEDKRIMLDI

SEZ6

621

Q53EL9
ELNVGKVSAEVMWHL

UNC13B

996

O14795
MIWGSIEKEHDKLHE

TERF1

156

P54274
QGECQWLHLDLIKEM

SRM

206

P19623
DGVMAHKVLNLLWNL

USP9Y

501

O00507
PDSLLHLMVKDWQLE

TRPM1

81

Q7Z4N2
WKIMERIENHGLKGL

ZFP82

101

Q8N141
FMQLEEKHEWEKILQ

ZZEF1

2656

O43149
CDMSHWLNVKVILEE

UGT2A3

31

Q6UWM9
LEQGKEAWSMKRHEI

ZNF85

56

Q03923
ELWRIQDVMEGLSKH

PLEKHA5

761

Q9HAU0
LWQHGEESMAKALVA

TRPM7

641

Q96QT4
HMESKWAVLGTLLQE

ZNF282

146

Q9UDV7
VFEALMVWIKHDLQA

KLHL38

196

Q2WGJ6