Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A4 SLC4A5	2.53e-04	6	83	2	GO:0008510
GeneOntologyMolecularFunction	netrin receptor activity	UNC5A UNC5D	2.53e-04	6	83	2	GO:0005042
GeneOntologyBiologicalProcess	mucociliary clearance	CCDC88C SPEF2 CFAP43	1.62e-05	13	81	3	GO:0120197
Domain	Actinin_actin-bd_CS	SPTBN5 FLNB FLNC SPTB	3.01e-06	23	83	4	IPR001589
Domain	ACTININ_2	SPTBN5 FLNB FLNC SPTB	3.01e-06	23	83	4	PS00020
Domain	ACTININ_1	SPTBN5 FLNB FLNC SPTB	3.01e-06	23	83	4	PS00019
Domain	IGc2	TYRO3 PTPRD FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	9.77e-06	235	83	8	SM00408
Domain	Ig_sub2	TYRO3 PTPRD FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	9.77e-06	235	83	8	IPR003598
Domain	IG	TYRO3 UNC5A PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	1.71e-05	421	83	10	SM00409
Domain	Ig_sub	TYRO3 UNC5A PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	1.71e-05	421	83	10	IPR003599
Domain	CH	SPTBN5 FLNB FLNC SPEF2 SPTB	1.82e-05	73	83	5	PS50021
Domain	CH-domain	SPTBN5 FLNB FLNC SPEF2 SPTB	2.07e-05	75	83	5	IPR001715
Domain	-	TYRO3 UNC5A FLNB FLNC PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	3.50e-05	663	83	12	2.60.40.10
Domain	Ig-like_fold	TYRO3 UNC5A FLNB FLNC PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	6.41e-05	706	83	12	IPR013783
Domain	Ig-like_dom	TYRO3 UNC5A PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 LILRA5 UNC5D IGDCC4	7.67e-05	503	83	10	IPR007110
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	1.16e-04	4	83	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	1.16e-04	4	83	2	PF01557
Domain	-	FAHD2B FAHD2A	1.16e-04	4	83	2	3.90.850.10
Domain	UPA	UNC5A UNC5D	1.93e-04	5	83	2	IPR033772
Domain	Na/HCO3_transpt	SLC4A4 SLC4A5	1.93e-04	5	83	2	IPR003024
Domain	UPA	UNC5A UNC5D	1.93e-04	5	83	2	PF17217
Domain	CH	SPTBN5 FLNB FLNC SPTB	2.00e-04	65	83	4	SM00033
Domain	Ig_I-set	TYRO3 UNC5A PTPRD CNTN3 UNC5D IGDCC4	2.02e-04	190	83	6	IPR013098
Domain	I-set	TYRO3 UNC5A PTPRD CNTN3 UNC5D IGDCC4	2.02e-04	190	83	6	PF07679
Domain	CH	SPTBN5 FLNB FLNC SPTB	2.66e-04	70	83	4	PF00307
Domain	-	SPTBN5 FLNB FLNC SPTB	2.81e-04	71	83	4	1.10.418.10
Domain	IG_LIKE	TYRO3 UNC5A PTPRD SLAMF9 FCGR2A VSIG10L CNTN3 UNC5D IGDCC4	3.27e-04	491	83	9	PS50835
Domain	ZF_UBR	UBR1 UBR3	4.04e-04	7	83	2	PS51157
Domain	zf-UBR	UBR1 UBR3	4.04e-04	7	83	2	PF02207
Domain	Znf_UBR	UBR1 UBR3	4.04e-04	7	83	2	IPR003126
Domain	ZnF_UBR1	UBR1 UBR3	4.04e-04	7	83	2	SM00396
Domain	ZU5	UNC5A UNC5D	6.88e-04	9	83	2	SM00218
Domain	Band3_cytoplasmic_dom	SLC4A4 SLC4A5	6.88e-04	9	83	2	IPR013769
Domain	Band_3_cyto	SLC4A4 SLC4A5	6.88e-04	9	83	2	PF07565
Domain	-	SLC4A4 SLC4A5	6.88e-04	9	83	2	3.40.1100.10
Domain	PH_dom-spectrin-type	SPTBN5 PSD4	6.88e-04	9	83	2	IPR001605
Domain	IG_FLMN	FLNB FLNC	8.58e-04	10	83	2	SM00557
Domain	HCO3_cotransp	SLC4A4 SLC4A5	8.58e-04	10	83	2	PF00955
Domain	HCO3_transpt_C	SLC4A4 SLC4A5	8.58e-04	10	83	2	IPR011531
Domain	ZU5	UNC5A UNC5D	8.58e-04	10	83	2	PS51145
Domain	PTrfase/Anion_transptr	SLC4A4 SLC4A5	8.58e-04	10	83	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A4 SLC4A5	8.58e-04	10	83	2	IPR003020
Domain	Filamin	FLNB FLNC	1.05e-03	11	83	2	PF00630
Domain	Peptidase_S9	DPP10 PREPL	1.05e-03	11	83	2	PF00326
Domain	FILAMIN_REPEAT	FLNB FLNC	1.05e-03	11	83	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB FLNC	1.05e-03	11	83	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC	1.05e-03	11	83	2	IPR017868
Domain	Peptidase_S9	DPP10 PREPL	1.05e-03	11	83	2	IPR001375
Domain	ZU5	UNC5A UNC5D	1.25e-03	12	83	2	PF00791
Domain	ZU5_dom	UNC5A UNC5D	1.25e-03	12	83	2	IPR000906
Domain	FN3	TYRO3 FLNC PTPRD CNTN3 IGDCC4	1.40e-03	185	83	5	SM00060
Domain	ig	TYRO3 PTPRD FCGR2A CNTN3 UNC5D	1.58e-03	190	83	5	PF00047
Domain	Immunoglobulin	TYRO3 PTPRD FCGR2A CNTN3 UNC5D	1.58e-03	190	83	5	IPR013151
Domain	FN3_dom	TYRO3 FLNC PTPRD CNTN3 IGDCC4	2.40e-03	209	83	5	IPR003961
Domain	Ig_2	FCGR2A VSIG10L LILRA5	4.21e-03	73	83	3	PF13895
Domain	Spectrin	SPTBN5 SPTB	4.65e-03	23	83	2	PF00435
Domain	KRAB	ZNF7 ZNF560 ZNF43 ZNF202 ZIM3 ZNF546	5.20e-03	358	83	6	PS50805
Domain	KRAB	ZNF7 ZNF560 ZNF43 ZNF202 ZIM3 ZNF546	5.20e-03	358	83	6	PF01352
Domain	fn3	TYRO3 PTPRD CNTN3 IGDCC4	5.89e-03	162	83	4	PF00041
Domain	KRAB	ZNF7 ZNF560 ZNF43 ZNF202 ZIM3 ZNF546	6.01e-03	369	83	6	SM00349
Domain	KRAB	ZNF7 ZNF560 ZNF43 ZNF202 ZIM3 ZNF546	6.09e-03	370	83	6	IPR001909
Domain	DEATH	UNC5A UNC5D	6.37e-03	27	83	2	SM00005
Domain	Spectrin_repeat	SPTBN5 SPTB	7.33e-03	29	83	2	IPR002017
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN5 FLNB FLNC SPTB ITGA3	6.09e-10	18	84	5	12119179
Pubmed	Analysis of Netrin 1 receptors during inner ear development.	UNC5A ITGA3 UNC5D	2.21e-06	11	84	3	17616930
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	FLNB FLNC USP19	2.21e-06	11	84	3	19015242
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	5.76e-06	2	84	2	15774318
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	5.76e-06	2	84	2	12525170
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	5.76e-06	2	84	2	9694715
Pubmed	Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice.	ST6GAL1 FUT8	5.76e-06	2	84	2	32141499
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNB FLNC	1.73e-05	3	84	2	11252955
Pubmed	Deletion of core fucosylation on alpha3beta1 integrin down-regulates its functions.	ITGA3 FUT8	1.73e-05	3	84	2	17043354
Pubmed	Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.	PTPRD SLITRK1	1.73e-05	3	84	2	25394468
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	1.73e-05	3	84	2	38287013
Pubmed	Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma.	NBAS DDX1	1.73e-05	3	84	2	17028906
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	1.73e-05	3	84	2	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNB FLNC	1.73e-05	3	84	2	11153914
Pubmed	Congenital Myasthenic Syndromes Overview	LAMB2 PREPL CHRNE	3.39e-05	26	84	3	20301347
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNB FLNC	3.45e-05	4	84	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB FLNC	3.45e-05	4	84	2	22802962
Pubmed	Dependence of surface monoclonal antibody binding on dynamic changes in FcgammaRIIb expression.	FCGR2A ST6GAL1	3.45e-05	4	84	2	18217946
Pubmed	CNS Neurons Deposit Laminin α5 to Stabilize Synapses.	LAMB2 ITGA3	3.45e-05	4	84	2	29091766
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	PTPRD PUS10 SPEF2 PRKCQ SLITRK1 DDX1	4.57e-05	265	84	6	19240061
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	TYRO3 PTPRD SLAMF9 CNTN3 IGDCC4	4.73e-05	162	84	5	25826454
Pubmed	Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.	NBAS PTPRD	5.74e-05	5	84	2	23991058
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB FLNC	5.74e-05	5	84	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNB FLNC	5.74e-05	5	84	2	12006559
Pubmed	Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).	LAMB2 ITGA3	5.74e-05	5	84	2	11964076
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNB FLNC	5.74e-05	5	84	2	17360453
Pubmed	Sequence and organization of the mouse poly (ADP-ribose) polymerase gene.	FCGR2A SERPINC1	8.59e-05	6	84	2	2498841
Pubmed	Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.	UBR1 UBR3	8.59e-05	6	84	2	17462990
Pubmed	Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.	UBR1 UBR3	8.59e-05	6	84	2	10805755
Pubmed	Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.	UNC5A UNC5D	1.20e-04	7	84	2	12351186
Pubmed	The isolation and characterization of the murine T cell antigen receptor zeta chain gene.	FCGR2A SERPINC1	1.20e-04	7	84	2	2787796
Pubmed	Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents.	UNC5A UNC5D	1.20e-04	7	84	2	20628609
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNB FLNC	1.20e-04	7	84	2	16076904
Pubmed	Genetic relationships of Mlsa among polymorphic loci on distal mouse chromosome 1.	FCGR2A SERPINC1	1.20e-04	7	84	2	3148667
Pubmed	Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.	PTPRD SLITRK1	1.20e-04	7	84	2	23345436
Pubmed	Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.	UBR1 UBR3	1.20e-04	7	84	2	21816346
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNB FLNC	1.60e-04	8	84	2	17145501
Pubmed	Genetic analysis of autoimmune gld mice. I. Identification of a restriction fragment length polymorphism closely linked to the gld mutation within a conserved linkage group.	FCGR2A SERPINC1	2.05e-04	9	84	2	2894402
Pubmed	The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.	LAMB2 ITGA3	2.05e-04	9	84	2	12217315
Pubmed	Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.	UNC5A UNC5D	2.05e-04	9	84	2	23457482
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	UBR1 UBR3	2.05e-04	9	84	2	17855541
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNB FLNC	2.05e-04	9	84	2	11807098
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	UBR1 MDN1 TONSL SPTLC1 VPS13A TWNK PREPL	2.54e-04	515	84	7	31617661
Pubmed	Gene mapping of the three subunits of the high affinity FcR for IgE to mouse chromosomes 1 and 19.	FCGR2A SERPINC1	2.56e-04	10	84	2	2531187
Pubmed	Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q.	FCGR2A SERPINC1	2.56e-04	10	84	2	3384439
Pubmed	Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.	FCGR2A SERPINC1	2.56e-04	10	84	2	8422330
Pubmed	Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen. Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.	FCGR2A SERPINC1	2.56e-04	10	84	2	1693656
Pubmed	A molecular genetic approach to gld "autoimmune" disease.	FCGR2A SERPINC1	2.56e-04	10	84	2	3416634
Pubmed	The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.	FLNB FLNC	2.56e-04	10	84	2	36357400
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	UNC5A CNTN3 UNC5D	2.76e-04	52	84	3	26633812
Pubmed	Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke.	SPTB UBR3	3.13e-04	11	84	2	19910543
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNB FLNC	3.13e-04	11	84	2	36579465
Pubmed	Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.	UNC5A UNC5D	3.13e-04	11	84	2	15186747
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	PWP1 CCDC88C TWNK CBX4 DDX1	3.27e-04	245	84	5	35652658
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 CCDC88C FLNC MDN1 LAMB2 TWNK TBC1D25 CEP192 CFAP43 ITGA3	3.31e-04	1105	84	10	35748872
Pubmed	Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer.	CBX4 MORC2	3.75e-04	12	84	2	36793866
Pubmed	HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.	UBR1 UBR3	3.75e-04	12	84	2	17360488
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN5 SPTB	4.42e-04	13	84	2	18796539
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 ADO TONSL CEP192 CBX4 DDX1 ZNF546	5.61e-04	588	84	7	38580884
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PWP1 UBR1 BPTF MDN1 MORC2 UNC5D USP19 SPICE1	5.71e-04	774	84	8	15302935
Pubmed	Laminin alpha5 chain is required for intestinal smooth muscle development.	LAMB2 ITGA3	5.93e-04	15	84	2	12921739
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMB2 ITGA3	6.77e-04	16	84	2	17601529
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	BPTF FLNB FLNC MDN1 SETSIP SPEF2 VPS13A TWNK TEX14 METTL25 DDX1	6.93e-04	1442	84	11	35575683
Pubmed	Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis.	FCGR2A SERPINC1	7.66e-04	17	84	2	9250876
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	LAMB2 ITGA3	7.66e-04	17	84	2	18082680
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	EPS8L2 LAMB2 ITGA3 USP19	1.03e-03	183	84	4	31932471
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	FLNB FLNC LLGL1 LAMB2	1.05e-03	184	84	4	23402259
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMB2 ITGA3	1.06e-03	20	84	2	22911573
Pubmed	SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.	MDN1 CBX4	1.17e-03	21	84	2	37014752
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNB FLNC	1.29e-03	22	84	2	18487259
Pubmed	Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.	UNC5A UNC5D	1.29e-03	22	84	2	22726835
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	GYS2 PCDH12	1.29e-03	22	84	2	19884348
Pubmed	Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors.	SLC4A5 DNALI1	1.29e-03	22	84	2	33304758
Pubmed	Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.	PTPRD SLITRK1	1.29e-03	22	84	2	38736483
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PWP1 SPTBN5 FER1L4 LAMB2 CFAP43 UNC5D	1.30e-03	496	84	6	31343991
Pubmed	Hereditary Ataxia Overview	CCDC88C TWNK PCDH12	1.46e-03	92	84	3	20301317
Pubmed	GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.	TYRO3 FCGR2A	1.54e-03	24	84	2	24871463
Pubmed	Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.	UNC5A UNC5D	1.54e-03	24	84	2	26633881
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	CCDC88C SPEF2 VPS13A MORC2	1.65e-03	208	84	4	33230847
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTBN5 SPTB	1.67e-03	25	84	2	8493579
Pubmed	Genome-wide association identifies multiple ulcerative colitis susceptibility loci.	FCGR2A PUS10	1.80e-03	26	84	2	20228799
Pubmed	Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1.	FCGR2A SERPINC1	1.95e-03	27	84	2	2574151
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	FLNB MDN1 LAMB2 DDX1	1.99e-03	219	84	4	31353912
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CCDC88C DPP10 CNTN3	2.02e-03	103	84	3	10819331
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	GYS2 PCDH12	2.24e-03	29	84	2	32798765
Pubmed	Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.	UNC5A UNC5D	2.40e-03	30	84	2	32562661
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	FLNB PCDH12	2.40e-03	30	84	2	19054571
Cytoband	2p24	NBAS DDX1	2.16e-04	12	84	2	2p24
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	TYRO3 UNC5A PTPRD CNTN3 UNC5D IGDCC4	1.25e-05	161	58	6	593
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTB	2.10e-04	7	58	2	1113
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR1 UBR3	2.10e-04	7	58	2	785
GeneFamily	Immunoglobulin like domain containing	TYRO3 FCGR2A VSIG10L CNTN3 IGDCC4	3.81e-04	193	58	5	594
GeneFamily	Fibronectin type III domain containing	TYRO3 PTPRD CNTN3 IGDCC4	1.73e-03	160	58	4	555
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	2.07e-05	3	78	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	2.07e-05	3	78	2	DOID:0111190 (implicated_via_orthology)
Disease	Thrombus	TYRO3 FCGR2A SERPINC1	2.49e-04	46	78	3	C0087086
Disease	Thrombosis	TYRO3 FCGR2A SERPINC1	3.00e-04	49	78	3	C0040053
Disease	Nephroblastoma	NBAS DDX1	3.06e-04	10	78	2	Orphanet_654
Disease	response to carboplatin, response to antineoplastic agent	FLNB SPEF2	3.06e-04	10	78	2	GO_0097327, GO_0097328
Disease	Dental enamel hypoplasia	PTPRD SLC4A4	4.48e-04	12	78	2	EFO_1001304
Disease	Charcot-Marie-Tooth Disease	SPTLC1 MORC2	4.48e-04	12	78	2	C0007959
Disease	Hereditary Motor and Sensory-Neuropathy Type II	SPTLC1 MORC2	5.28e-04	13	78	2	C0270914
Disease	Colorectal Carcinoma	FLNC PTPRD ZNF560 ZNF43 PUS10 FRMPD2 VPS13A DNALI1	5.34e-04	702	78	8	C0009402
Disease	anemia (implicated_via_orthology)	SLC4A4 SLC4A5	7.08e-04	15	78	2	DOID:2355 (implicated_via_orthology)
Disease	thrombosis (is_implicated_in)	FCGR2A SERPINC1	7.08e-04	15	78	2	DOID:0060903 (is_implicated_in)
Disease	daytime rest measurement	CCDC88C ADO DPP10 SPTB PREPL	1.12e-03	295	78	5	EFO_0007828
Disease	response to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement	PTPRD FUT8	1.27e-03	20	78	2	EFO_0803359, EFO_0803362
Disease	systemising measurement	NBAS FUT8	1.40e-03	21	78	2	EFO_0010221
Disease	N-glycan measurement	ST6GAL1 FUT8	1.54e-03	22	78	2	EFO_0004999
Disease	peripheral neuropathy, response to antimicrotubule agent	CNGB1 SLITRK1	1.68e-03	23	78	2	EFO_0003100, EFO_0005260
Disease	Myasthenic Syndromes, Congenital	LAMB2 PREPL	1.83e-03	24	78	2	C0751882
Disease	digestive system infectious disorder	TYRO3 FLNB	2.15e-03	26	78	2	MONDO_0043424
Disease	indole-3-propionate measurement	NBAS DDX1	2.32e-03	27	78	2	EFO_0010501

Protein segments in the cluster

Peptide	Gene	Start	Entry
WEEGLVLPLAEEELP	SYT13	221	Q7L8C5
IILDLELEEAVWQPE	CFAP43	1051	Q8NDM7
LPREVWLLETPQADD	ADO	241	Q96SZ5
PQWEVEELPVEELLL	GYS2	16	P54840
EELPVEELLLFEVAW	GYS2	21	P54840
EPPWINVLQEDSVTL	FCGR2A	46	P12318
LPDLDEVPWTLQELE	BTBD11	91	A6QL63
LTPEVLQEWLDELEE	SERPINC1	331	P01008
PVIIETWVAEEELEL	BPTF	2006	Q12830
EVWELNPPEVEDSVL	DPP10	166	Q8N608
PSELVWLPEIVLENN	CHRNE	101	Q04844
WEKDQVTLPEEPRLI	IGDCC4	176	Q8TDY8
WELEIVVEDQGSPPL	PCDH12	671	Q9NPG4
EEELVVLDLQTPGWP	LLGL1	366	Q15334
EINWEELERKEIDPP	PRKCQ	636	Q04759
ILQVWSEPSDLLEIP	LILRA5	221	A6NI73
EWILLDEINLAAPEI	MDN1	831	Q9NU22
FIPRPETEELVEWVL	HEMK1	131	Q9Y5R4
VWEELVDLPPETVLA	METTL25	46	Q8N6Q8
PLWDELLVFEQLIVD	FER1L4	806	A9Z1Z3
DLQWLELPDVAPEEL	CCDC88C	171	Q9P219
DWLLPTDIQAESIPL	DDX1	21	Q92499
DDWLGVPQVITPEEI	FLNB	206	O75369
ELVEELPAEIELWLV	ITGA3	981	P26006
DDWLGVPQVIAPEEI	FLNC	226	Q14315
WPPELGETIERENEL	LANCL3	276	Q6ZV70
RLEPQVPEQWAELEL	LAMB2	626	P55268
VPEQWAELELIVQRP	LAMB2	631	P55268
EVVLPPQSQEVDWEV	FAHD2A	146	Q96GK7
AIPLWELPDQEEVQL	TWNK	161	Q96RR1
EPPIVTDELEDLNLW	MON2	1226	Q7Z3U7
ELVSPEDLLEWLRPF	NBAS	2081	A2RRP1
PVDVLQEAPWEVEGL	EPS8L2	426	Q9H6S3
EEEGIDEVIVPLPTW	MORC2	136	Q9Y6X9
ILELDVESVDVDWPP	PUS10	511	Q3MIT2
RQEPLIPVEQIVEAW	BTBD19	241	C9JJ37
EVVLPPQSQEVDWEV	FAHD2B	146	Q6P2I3
LPELEQEWQTPELSA	FRMPD2	1171	Q68DX3
LDVNLEEREAWLLPP	HEATR4	181	Q86WZ0
LIEAPEIPDLENRIW	IFIT1B	26	Q5T764
TWEPEENILDPRLLI	CBX4	41	O00257
EEILNAILPPREWVE	DNALI1	66	O14645
LDQLASEEPWTVLPE	CEP192	2121	Q8TEP8
LKQLCEDWEVVPEPV	DCK	41	P27707
VLDLEEEGLWPELLD	FBXO27	166	Q8NI29
VLPDLLEEEDPWRSL	SLC39A13	336	Q96H72
ELVITWDPVPEELQN	CNTN3	716	Q9P232
LLWDPSVLPEREVEE	MIER2	226	Q8N344
DLEKLLTEWPDTIPL	PTGR1	101	Q14914
DPQPITDEEEGLIWV	PTPRD	1256	P23468
IRPQPWLEKEIEEAT	FUT8	336	Q9BYC5
WPIPLEEELLETLQK	SPEF2	1546	Q9C093
LDEDLERWLQPPEES	TEX14	1406	Q8IWB6
PLLEDWDIISPKDVI	TBC1D25	131	Q3MII6
LPEDTVLWELESEPD	PSD4	291	Q8NDX1
ELEEVIKDDIWPNPL	SETSIP	226	P0DME0
PWELWDILQEISPEE	ST6GAL1	301	P15907
PWLEDDDSLLPAEIE	IMPG2	631	Q9BZV3
EKEELIEEWQPEPLV	SPTLC1	56	O15269
NWLEPIEVELRAPTV	SPTBN5	2801	Q9NRC6
LPPTVEIIEKEQNWE	SPICE1	566	Q8N0Z3
EPDLVLEEVEPPWED	CNGB1	301	Q14028
VIEVWDLDIVDSLEP	PWP1	216	Q13610
LEQGKEPWLEEEEVL	ZIM3	61	Q96PE6
RIWQELEAEEEPVPE	USP19	1246	O94966
VWEPLLEPLEIDQTE	VPS13A	1781	Q96RL7
IPGIAEILLEDNPWD	SLITRK1	201	Q96PX8
VVREWLDNIPEEPIL	RP1L1	956	Q8IWN7
LTPQEWLPEEFLERI	PYROXD2	351	Q8N2H3
DEVLAEVTSWDLPPL	TONSL	1001	Q96HA7
PDVITLLEQEKEPWI	ZNF546	106	Q86UE3
IWEEEKELPPELQIR	UBR1	206	Q8IWV7
DEFLDEVIVLPPGEW	SLC4A5	391	Q9BY07
TLPLTLEELEEWGNP	PREPL	596	Q4J6C6
DLEDETLWVEERLPL	SPTB	1486	P11277
PLEIPPDEEVENIIW	SLAMF9	41	Q96A28
VPAAEVEWLKNEEPI	UNC5D	186	Q6UXZ4
IPPAEVEWLRNEDLV	UNC5A	176	Q6ZN44
DLITCLEQEKEPWEP	ZNF43	51	P17038
WLDDIEILIQPEIPK	UBR3	1111	Q6ZT12
DEFLDEVIVLPPGEW	SLC4A4	371	Q9Y6R1
VEISWPLDLKVPLED	VSIG10L	836	Q86VR7
REEEPWVPDIQEPQE	ZNF202	291	O95125
SGLILEWEEVIPEAP	TYRO3	336	Q06418
PELISRLEQGEEPWV	ZNF7	51	P17097
WLEEEEELSTLPRVL	ZNF560	161	Q96MR9
EEIEKWIPELSPEEI	ZRANB3	96	Q5FWF4