Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

KALRN MYCBP2 TBC1D22A RGS3 DENND3 RASGRP3 NRP1

1.48e-04507467GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

KALRN MYCBP2 TBC1D22A RGS3 DENND3 RASGRP3 NRP1

1.48e-04507467GO:0030695
DomainEF-hand_5

RCN1 RASGRP3 RCN3

3.30e-0525473PF13202
Domain-

RCN1 PLCB4 RPTN RASGRP3 RCN3

4.87e-042614751.10.238.10
DomainEF-hand_1

RCN1 RPTN RASGRP3 RCN3

5.73e-04152474PF00036
DomainEF-hand-dom_pair

RCN1 PLCB4 RPTN RASGRP3 RCN3

7.49e-04287475IPR011992
DomainEF_Hand_1_Ca_BS

RCN1 RPTN RASGRP3 RCN3

9.70e-04175474IPR018247
DomainEF_HAND_1

RCN1 RPTN RASGRP3 RCN3

1.71e-03204474PS00018
DomainEF_HAND_2

RCN1 RPTN RASGRP3 RCN3

2.68e-03231474PS50222
DomainEF_hand_dom

RCN1 RPTN RASGRP3 RCN3

2.72e-03232474IPR002048
Pubmed

Circulating Reticulocalbin 1 and Reticulocalbin 3 in Systemic Sclerosis Patients: Results of a Case Control Study.

RCN1 RCN3

1.79e-06247227468573
Pubmed

Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.

SEMA6C NRP1

1.78e-05547220512151
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SETX PPIP5K2 WDR11 RGS3 DENND3 NRP1 FANCA

2.53e-0565047738777146
Pubmed

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

EPB41L4A NRP1

6.40e-05947236449624
Pubmed

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.

SEMA6C NRP1

6.40e-05947228751609
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

SEMA6C NRP1

1.17e-041247224179230
Pubmed

Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.

USP6 PLCB4 G3BP1

1.40e-047447323604909
Pubmed

Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

SEMA6C NRP1

2.12e-041647222632726
Pubmed

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.

SAFB2 EPB41L4A

2.70e-041847221810271
Pubmed

Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.

PTCH2 WDR11

3.01e-041947237516749
Pubmed

Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.

SEMA6C NRP1

3.01e-041947215051154
Pubmed

Neonatal Respiratory Failure with Retarded Perinatal Lung Maturation in Mice Caused by Reticulocalbin 3 Disruption.

RCN1 RCN3

3.34e-042047226252542
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYCBP2 DENND3 RASGRP3

3.41e-0410047310048485
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

TENM1 ITGA11

4.06e-042247235245678
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RCN1 DYNC1LI1 GPATCH8 PPIP5K2 MYCBP2 TBC1D22A

4.42e-0473347634672954
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

SEMA6C NRP1

4.84e-042447215869472
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

USP6 KLHL1 MID1IP1 RPTN

5.01e-0427247418187620
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SAFB2 DYNC1LI1 SETX GPATCH8 PPIP5K2 KALRN MYCBP2

5.87e-04108247738697112
Pubmed

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

ITGA11 KALRN

6.61e-042847218839057
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

SEMA6C NRP1

7.59e-043047219054571
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

RCN1 G3BP1 KALRN SLC27A2

7.59e-0430447432235678
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

USP6 PLCB4 PPIP5K2 G3BP1 WDR11

7.68e-0453647515840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

USP6 PLCB4 PPIP5K2 G3BP1 WDR11

7.81e-0453847510512203
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

TENM1 NRP1

8.11e-043147227798109
Pubmed

Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.

PTCH2 NRP1

8.64e-043247214973295
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

PTCH2 POLR1F G3BP1 RGS3

8.87e-0431747417620599
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

RCN1 ITGA11 MYCBP2 RCN3 FAM20B NRP1 FANCA

1.08e-03120147735696571
Pubmed

Tagging genes with cassette-exchange sites.

SAFB2 GPATCH8 UTP25 PPTC7

1.09e-0333547415741177
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

TENM1 KLHL1

1.22e-033847222952603
InteractionSORBS1 interactions

TENM1 DYNC1LI1 G3BP1 KALRN MYCBP2

9.75e-06123475int:SORBS1
GeneFamilyEF-hand domain containing

RCN1 RPTN RASGRP3 RCN3

6.51e-04219334863
CoexpressionGSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_UP

SETX MYCBP2 TBC1D22A FAM161A DENND3 B4GALT6 RASGRP3

6.58e-08200477M9354
CoexpressionGSE16385_MONOCYTE_VS_MACROPHAGE_DN

CTNND2 KALRN MYCBP2 RASGRP3 PPTC7

2.91e-05200475M7901
CoexpressionGSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN

G3BP1 WDR11 TBC1D22A RGS3 B4GALT6

2.91e-05200475M7174
CoexpressionLAKE_ADULT_KIDNEY_C25_ENDOTHELIAL_CELLS_UNASSIGNED

PLCB4 EPB41L4A KALRN

4.36e-0538473M39244
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

PLCB4 EPB41L4A KALRN RASGRP3 NRP1

1.04e-06172475c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 KLHL1 EPB41L4A KALRN B4GALT6

1.78e-0619247581baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 KLHL1 EPB41L4A KALRN B4GALT6

1.78e-0619247552acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA6C PLCB4 EPB41L4A KALRN B4GALT6

1.78e-06192475717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3 NRP1

1.83e-06193475e1d546165dcc2392f540162206852c4717d7306f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLCB4 EPB41L4A KALRN RGS3

1.89e-051504744f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRYAA GALNTL6 KLHL1 CTNND2

2.15e-051554745c7b68b59244525e3714806c205a57a2daebf423
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SEMA6C PLCB4 PPIP5K2 EPB41L4A

2.50e-05161474b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 CACNG4 KLHL1 RCN3

3.02e-051694747be742160e3e7e6c8f86b037be4e425f4d4cf663
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 CACNG4 KLHL1 RCN3

3.02e-051694744ccf5cfa4fe72d3af056d658460a9ccaa07b01be
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRYAA GALNTL6 KLHL1 SLC27A2

3.09e-051704748ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIT FAM161A RPTN SLC27A2

3.39e-05174474179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIT FAM161A RPTN SLC27A2

3.39e-051744749165a1094d345328e58962f4b2a20334c3e93ead
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA11 KLHL1 VIT NRP1

3.78e-05179474747a32460b257fffca30527b56a74720eb9c12e4
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 MYCBP2 DENND3 RASGRP3

3.86e-05180474423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 ITGA11 PLCB4 NRP1

3.86e-05180474e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 MYCBP2 DENND3 RASGRP3

3.86e-05180474dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 ITGA11 PLCB4 NRP1

4.03e-0518247472e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 ITGA11 PLCB4 NRP1

4.03e-0518247405c167158815bf25d509df59ab386e1990712765
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CRYAA GALNTL6 KLHL1

4.06e-056347355f11bb2970a8159166e71af34a0446ecee594e6
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

PLCB4 KALRN DENND3 NRP1

4.12e-05183474273db6a3b00a93ca852498471187b642b5368185
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

PLCB4 KALRN DENND3 NRP1

4.12e-05183474e3835db4795362b0442d5893baf2a78efcc20428
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

CDR2 WDR11 DENND3 FANCA

4.21e-051844740e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

PLCB4 KALRN DENND3 NRP1

4.30e-05185474ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

4.30e-05185474808d5e880069aff8866cd2c733b9fe568a37701f
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 RGS3 RASGRP3 NRP1

4.39e-051864740ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

APOBEC3D UTP25 WDR11 FANCA

4.39e-05186474927723ad579bbd9947ff525bd501e222d3fa9289
ToppCelldroplet-Liver-Npc-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 SAFB2 DYNC1LI1 DENND3

4.39e-0518647475258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 GALNTL6 KLHL1 NRP1

4.39e-0518647432af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.67e-05189474e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.67e-051894745559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.67e-05189474f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CACNG4 CTNND2 EPB41L4A DENND3

4.67e-051894745a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 PLCB4 DENND3 RASGRP3

4.77e-0519047425525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 PLCB4 DENND3 RASGRP3

4.77e-05190474a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.77e-05190474bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.77e-05190474d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.77e-0519047438a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.97e-051924740986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.97e-051924748f20d3511dcb44445592b17d005a53da0052ae56
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

4.97e-051924740aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 DENND3 RASGRP3 NRP1

4.97e-05192474b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

SEMA6C PLCB4 CTNND2 NRP1

4.97e-05192474e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

5.07e-051934746e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 RASGRP3 NRP1

5.07e-05193474aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 RASGRP3 NRP1

5.07e-05193474c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

5.17e-051944740b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

5.17e-051944741d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ITGA11 VIT RGS3 RCN3

5.17e-05194474292ce9021678534c9eedb367b9772a9d976208a8
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCB4 CTNND2 EPB41L4A RASGRP3

5.17e-0519447443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNG4 CTNND2 EPB41L4A DENND3

5.27e-05195474a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA11 VIT CDH19 RCN3

5.38e-05196474d5ed41fa111750e6b363c04cccc40a47dd774852
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RCN1 VIT RGS3 RCN3

5.38e-05196474760885dc608c82768fe0decd63ed9fda8315f453
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RCN1 VIT RGS3 RCN3

5.60e-051984741f956e369e00d37835095a001db4b62a79014532
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RCN1 VIT RGS3 RCN3

5.60e-05198474dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RCN1 ITGA11 RGS3 RCN3

5.71e-05199474d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RCN1 ITGA11 RGS3 RCN3

5.71e-05199474bf138cc692df727e087d140c014149ee5da00d9d
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA11 VIT RGS3 RCN3

5.82e-052004743c898e81444b001835c3f1bbc68183078701b135
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLCB4 SETX EPB41L4A NRP1

5.82e-05200474dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA11 VIT RGS3 RCN3

5.82e-052004743eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM1 ITGA11 VIT NRP1

5.82e-052004740c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CRYAA GALNTL6 KLHL1

3.18e-0412647384dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GALNTL6 KLHL1 SLC27A2

3.18e-041264733a14d4eb8803827946c36faeeb7ae2913418d421
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RCN1 GALNTL6 CACNG4

3.56e-041314739ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-9|TCGA-Kidney / Sample_Type by Project: Shred V9

GALNTL6 CTNND2 CDH19

3.64e-04132473f1ef63a4842ab6ca584a9dcc2dd5b2108fc990aa
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRYAA RCN1 SLC27A2

3.72e-04133473fc319644868078ea0f88a71d55f5e858c6848b50
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

GALNTL6 CLCN1 SLC27A2

4.42e-04141473330f944b38c3170dfc79ab033fae7b9ab71e840d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 DENND3 NRP1

4.60e-041434737a7a9829ba63468c9745904d9e993590051207ab
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 RCN1 FAM20B

4.89e-04146473159dd157a74f3c27dc1a1dcbbf0ed8f9462cac9e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_atypical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 CTNND2 DENND3

5.09e-04148473b7b5521162effc1024e7c399f690cd86d0b2f750
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SETX KALRN RCN3

5.39e-04151473b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDR2 SLC27A2 NRP1

5.60e-04153473d6526d17826470534b766df144c74e73eb83fdad
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTCH2 B4GALT6 FANCA

5.60e-0415347392a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL1 VIT CDH19

5.71e-0415447330cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL1 VIT CDH19

5.71e-04154473ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL1 VIT CDH19

5.71e-0415447342bd8f88fd075a2d4edde394785decad88a2660a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL1 VIT CDH19

5.71e-041544736425d9861148586466febd6eceae1b1f9b9a14c1
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SEMA6C CACNG4 CTNND2

5.82e-04155473010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

TENM1 RCN1 RGS3

6.27e-041594739f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

GALNTL6 KLHL1 CTNND2

6.27e-041594735335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GALNTL6 KLHL1 SLC27A2

6.38e-041604730bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

PLCB4 EPB41L4A KALRN

6.38e-041604730cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYAA CDR2 SLC27A2

6.61e-041624736972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 CACNG4 RCN3

6.61e-04162473ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA11 VIT CDH19

6.73e-041634738f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTCH2 CACNG4 RASGRP3

6.73e-041634737864e966c228282b4b63c43164dba3faba21026d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA6C CLCN1 FAM20B

6.85e-041644734ade97931ae1780af7836d988fe117a10b3e88a1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RCN1 GALNTL6 EPB41L4A

7.10e-0416647359d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

GALNTL6 EPB41L4A RASGRP3

7.10e-041664738de8f388f24436b84e19ef460476fdbda4d16abf
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLCB4 CLCN1 RASGRP3

7.10e-04166473f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNTL6 KLHL1 CTNND2

7.22e-041674733edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYAA CDR2 SLC27A2

7.22e-0416747340d102e01ccbc7262d00fafd59ca5234909009cb
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLCB4 EPB41L4A KALRN

7.22e-04167473d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SEMA6C CLCN1 FAM20B

7.35e-041684732fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GALNTL6 SEMA6C SLC27A2

7.48e-0416947378eb70dd916724e476eabccf18fb7fcec4210308
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RCN1 SEMA6C RCN3

7.48e-0416947358e22f9119240664515fe91ca53812611a8f17d6
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 RASGRP3 FANCA

7.48e-041694734e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 KALRN DENND3

7.61e-0417047399dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 KALRN DENND3

7.61e-041704733a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 KALRN DENND3

7.61e-04170473cdb6fad277f284c3fd5a6f45672a8edc24715882
DrugMethylatropine nitrate [52-88-0]; Up 200; 11uM; PC3; HT_HG-U133A

CTNND2 RNF6 TBC1D22A RCN3 SLC27A2 FANCA

3.11e-061974767253_UP
DrugHarpagoside [19210-12-9]; Down 200; 8uM; PC3; HT_HG-U133A

SAFB2 RNF6 TBC1D22A DENND3 RCN3 FANCA

3.29e-061994766636_DN
DiseaseInsulinogenic index measurement

PPIP5K2 MYCBP2

2.27e-055452EFO_0009961
Diseasevon Willebrand factor measurement, coagulation factor measurement

SAFB2 EPB41L4A

1.49e-0412452EFO_0004629, EFO_0004634
Diseasecardiac troponin I measurement

ITGA11 KLHL1 PPIP5K2 NRP1

1.51e-04176454EFO_0010071
Diseasebrain connectivity measurement

POLR1F ITGA11 MOB4 NRP1 FANCA

3.49e-04400455EFO_0005210
Diseaseneuroblastoma

EPB41L4A KALRN RPTN

7.45e-04116453EFO_0000621
Diseasefear of minor pain measurement

TENM1 TBC1D22A

1.03e-0331452EFO_0008340
Diseasecortical thickness

POLR1F VIT G3BP1 MYCBP2 TBC1D22A DENND3 NRP1

1.38e-031113457EFO_0004840
Diseaseamyotrophic lateral sclerosis

POLR1F KALRN B4GALT6

1.42e-03145453MONDO_0004976
Diseaseclinical treatment

GALNTL6 MYCBP2

1.80e-0341452EFO_0007056
Diseaseage at assessment, pelvic organ prolapse

CTNND2 NRP1

1.97e-0343452EFO_0004710, EFO_0008007
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

GALNTL6 CACNG4

2.26e-0346452EFO_0005325, HP_0012735
Diseasehomocysteine measurement

POLR1F FANCA

2.26e-0346452EFO_0004578
Diseasecomplement factor H-related protein 1 measurement

GALNTL6 EPB41L4A

3.32e-0356452EFO_0600054
Diseasecommon carotid intimal medial thickness

CTNND2 EPB41L4A

4.72e-0367452EFO_0004860
Diseasecytokine measurement

PPIP5K2 MYCBP2 SLC27A2 FANCA

5.28e-03461454EFO_0004873

Protein segments in the cluster

PeptideGeneStartEntry
NHRQEVYFRFENHAE

APOBEC3D

66

Q96AK3
HLNYEHRVFNSEEFL

DENND3

376

A2RUS2
NYDESFFEDQVHHRP

CTNND2

1166

Q9UQB3
DDAHGNFQYDHEAFL

RCN3

46

Q96D15
NFQYDHEAFLGREVA

RCN3

51

Q96D15
QDYDHAQAEARHLVY

RCN1

276

Q15293
FHEHFFFPVQEEDDQ

RGS3

201

P49796
ADAGEEDLEQQFHYH

MID1IP1

136

Q9NPA3
EHDYRDEHFDFIQSH

DYNC1LI1

256

Q9Y6G9
GNHFDQYEEGHLEIE

GPATCH8

16

Q9UKJ3
EHIIFGNIQEIYDFH

KALRN

1326

O60229
YGEDVVHEFHLNDYR

ITGA11

206

Q9UKX5
YVEVFDGENENGHFR

NRP1

86

O14786
GGEVVHRSDEQQHYF

PPTC7

166

Q8NI37
FHDVDHLPENDRNYY

B4GALT6

226

Q9UBX8
FRINHFPEDNDYDHD

CACNG4

81

Q9UBN1
DLRQHFVYDHVFAEK

CDR2

166

Q01850
VHNDIFRYQDEVFGG

G3BP1

126

Q13283
YFHEDAAIREEAFLH

FANCA

1341

O15360
GLYQFDRVAVHHAEA

MBLAC2

91

Q68D91
NERQDDHGYISREFH

CRYAA

101

P02489
DFVNFPDIHHSNEEY

FAM161A

81

Q3B820
FHHVNLVEIDYFGLR

EPB41L4A

46

Q9HCS5
RDESIEEHHFYFNLS

CDH19

496

Q9H159
EDHDDSAYRENGFNI

GALNTL6

96

Q49A17
IDVIDHNHFGYEAQA

GALNTL6

261

Q49A17
EDYEAVFVGNIDDHF

UTP25

411

Q68CQ4
KFQGFHVAEERNIHY

PLCB4

576

Q15147
YFHHRQIFDEYENET

MOB4

171

Q9Y3A3
HENFIYFHDRVGDTF

SLC27A2

471

O14975
ESVFRNYDHDHDGYI

RASGRP3

426

Q8IV61
RQLYEHFRGDYQTHD

PTCH2

326

Q9Y6C5
NHENRGFEIHGEDYT

RNF6

156

Q9Y252
ERNDIQDLHEYHSGY

SETX

1826

Q7Z333
ENLHFTIEGRDTHYF

TENM1

2561

Q9UKZ4
HHHENFVGYQDDNLF

MYCBP2

3401

O75592
IYGHHKEQFSDREQD

CLCN1

61

P35523
EHQFFEDGDVQRHLY

ZNF511

46

Q8NB15
GNADRHHYESFQDDE

FAM20B

286

O75063
DHSFFVDEFDNLHQY

VIT

646

Q6UXI7
EHGDHVYFFFREVSV

SEMA6C

231

Q9H3T2
HDFDHRDRGQYQDHA

SAFB2

766

Q14151
YDDQGHIHLNIEADF

POLR1F

106

Q3B726
IEHYYDSRNDEVHQD

TBC1D22A

261

Q8WUA7
YRHFFHHADEDDEEE

PPIP5K2

21

O43314
REHFVFTDIDGQVYH

WDR11

676

Q9BZH6
LDQDRDGHIDFHEYL

RPTN

61

Q6XPR3
DHEVALANGFLYEHE

USP6

1261

P35125
EEFYQAVHHAEQTFR

KLHL1

186

Q9NR64