Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenodecreased femur size

XYLT1 BPNT2 COL12A1 FSHR RUNX3

3.69e-05130415MP:0030825
MousePhenoabnormal cartilage morphology

XYLT1 BPNT2 COL12A1 DSG3 ARID5B PRG4 MEX3C

4.84e-05336417MP:0000163
MousePhenoabnormal snout morphology

XYLT1 BPNT2 DSG3 ARID5B HIPK2 F7

9.55e-05257416MP:0000443
MousePhenoabnormal cartilage development

XYLT1 BPNT2 COL12A1 ARID5B MEX3C

1.39e-04172415MP:0000164
MousePhenoabnormal long bone epiphyseal plate morphology

XYLT1 BPNT2 ARID5B PRG4 MEX3C

1.39e-04172415MP:0003055
MousePhenoabnormal epiphyseal plate morphology

XYLT1 BPNT2 ARID5B PRG4 MEX3C

1.96e-04185415MP:0006395
DomainLRR_5

FSHR PODN

4.34e-0410592PF13306
DomainLRR_5

FSHR PODN

4.34e-0410592IPR026906
DomainFERM_central

TYK2 FRMPD3 PTPN21

4.98e-0449593IPR019748
DomainFERM_domain

TYK2 FRMPD3 PTPN21

4.98e-0449593IPR000299
DomainFERM_1

TYK2 FRMPD3 PTPN21

5.28e-0450593PS00660
DomainFERM_2

TYK2 FRMPD3 PTPN21

5.28e-0450593PS00661
DomainFERM_3

TYK2 FRMPD3 PTPN21

5.28e-0450593PS50057
DomainBand_41_domain

TYK2 FRMPD3 PTPN21

5.28e-0450593IPR019749
DomainB41

TYK2 FRMPD3 PTPN21

5.28e-0450593SM00295
DomainVWA

COL12A1 VWF VWA8

7.37e-0456593PF00092
DomainVWFA

COL12A1 VWF VWA8

2.22e-0382593PS50234
DomainVWA

COL12A1 VWF VWA8

2.38e-0384593SM00327
DomainUbiquitin-rel_dom

FAF2 FRMPD3 PTPN21 RGL2

2.72e-03184594IPR029071
Pubmed

Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma.

RUNX3 MEX3C

3.03e-06261238424632
Pubmed

Factor VIIa induced release of von Willebrand factor from human umbilical vein endothelial cells by a tyrosine kinase dependent pathway.

VWF F7

3.03e-06261212083486
Pubmed

Relationships between sleep duration and von Willebrand factor, factor VII, and fibrinogen: Whitehall II study.

VWF F7

3.03e-06261220651279
Pubmed

Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.

TYK2 PXK

3.03e-06261222592861
Pubmed

Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development.

RUNX3 PRG4

9.07e-06361236261443
Pubmed

Changes in procoagulants track longitudinally with insulin resistance: findings from the coronary artery risk development in young adults (CARDIA) study.

VWF F7

9.07e-06361224344794
Pubmed

Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.

TLE1 HIPK2

3.02e-05561224270405
Pubmed

Genomewide association study for onset age in Parkinson disease.

DSG3 QSER1

4.52e-05661219772629
Pubmed

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.

VWF F7

4.52e-05661220231535
Pubmed

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

TLE1 RUNX3

4.52e-0566129751710
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

FEM1B FAF2 VWA8 PRPF3 USP32 F7 TNPO3 DDOST MPP7

6.11e-05100561919615732
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

VWF F7

6.32e-0576129384381
Pubmed

Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation.

TLE1 HIPK2

8.42e-05861215896780
Pubmed

Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction.

VWF F7

1.35e-041061220036902
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL12A1 VWF PRG4 F7

1.55e-0415361425037231
Pubmed

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

TNPO3 PXK

1.65e-041161218204446
Pubmed

Multiple sclerosis susceptibility alleles in African Americans.

TYK2 CD6

2.33e-041361219865102
Pubmed

Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control.

FAF2 DDOST

3.13e-041561221857022
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

PPP2R3A PRPF3 FRMPD3 RGL2 TNPO3 MPP7

3.43e-0453361625544563
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SDK2 ABCB9 ATP10D

8.01e-0410361310819331
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

TYK2 ARID5B PXK

1.02e-0311261324390342
Pubmed

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

TNPO3 PXK

1.03e-032761223740937
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TYK2 PPP2R3A PRPF3 ARID5B HIPK2 QSER1 CASC2 F7 LRCH3

1.10e-03148961928611215
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PRPF3 TLE1 ARID5B QSER1

1.27e-0326861433640491
Pubmed

HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.

PPP2R3A TLE1

1.45e-033261211748221
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

TYK2 WWC2 FAF2 PTPN21 TNPO3 DDOST MPP7

1.55e-0397461728675297
Pubmed

Early embryonic expression of murine coagulation system components.

VWF F7

1.64e-033461211154109
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

KAT7 QSER1

1.73e-033561227142060
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

TYK2 FRMPD3 PTPN21

2.43e-04504431293
GeneFamilyFibronectin type III domain containing

IGFN1 SDK2 COL12A1 ATF7IP

6.09e-04160444555
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|356C / Donor, Lineage, Cell class and subclass (all cells)

CD84 CD6 CASKIN1 FRMPD3 RUNX3

2.34e-06158605cf1b77abd05f18526679c0d305b4dd2caef2b306
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL12A1 CD6 PODN ADGRG4

9.02e-06976040d68bf2dfb9c221375b70b055f735536afb18f65
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SERPINA11 SDK2 COL12A1 TMPRSS7

2.09e-051206042b7596946f9268c4202348adf3069decd8313bb0
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 DENND4B RUNX3

4.75e-05148604bbf4933582b50b3412c805de5ed137107c996236
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 DENND4B RUNX3

4.75e-051486046543860e3207a7de92a35bb6004be51287582f7a
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 DENND4B RUNX3

4.75e-0514860479e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD84 TNFAIP8L2 TMPRSS7 RUNX3

4.88e-0514960443d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD84 TNFAIP8L2 TMPRSS7 RUNX3

4.88e-051496041c5a2572741c47246d455c865e8e1677c9f49598
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFAIP8L2 CD6 ABCB9 RUNX3

4.88e-051496044fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SDK2 COL12A1 PODN SSTR3

5.01e-051506049d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

XYLT1 SDK2 TLE1 HIPK2

7.42e-05166604773673a5d0430640439845b264740bfbbdad0cb2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

XYLT1 SDK2 TLE1 HIPK2

7.59e-051676043ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

WWC2 COL12A1 PTPN21 F7

7.95e-05169604815474855a70498a74e52f6583113c63b7267a0c
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 DENND4B RUNX3

8.70e-05173604513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

SERPINA11 FAF2 DSG3 PRG4

8.90e-05174604fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellfacs-BAT-Fat-18m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 CD6 ABCB9 RUNX3

9.10e-05175604bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 COL12A1 PODN ADGRG4

9.10e-05175604795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

XYLT1 AOC1 ABCB9 ATP10D

9.30e-05176604581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD84 CD6 RUNX3 MPP7

9.30e-051766049d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD84 CD6 RUNX3 MPP7

9.30e-05176604bb41e9478373726eb460af764de0277b2d09928e
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD84 CD6 RUNX3 PXK

9.72e-05178604da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCelldroplet-Tongue-nan-24m-Myeloid-basal_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 CD6 RUNX3

9.72e-051786049423e209de94d26e96117581c95dc069850225d3
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

XYLT1 SDK2 RUNX3 PRG4

9.72e-051786048591a40fced747ac16b3e8ebc7a22dfb3ad76da2
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD84 CD6 RUNX3 PXK

9.72e-05178604580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCelldroplet-Tongue-nan-24m-Myeloid-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 TNFAIP8L2 CD6 RUNX3

9.93e-051796041b079d80f789473701c781f3431ad306e9766797
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 ABCB9 CASKIN1 KCNJ16

1.08e-0418360425c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 COL12A1 PODN ADGRG4

1.10e-04184604e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL12A1 KCNJ16 PODN PRG4

1.13e-04185604506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 ABCB9 CASKIN1 KCNJ16

1.13e-04185604dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 ABCB9 CASKIN1 KCNJ16

1.13e-04185604bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CD6 ATF7IP RUNX3 MPP7

1.15e-041866049d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellControl-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

CD6 ATF7IP RUNX3 MPP7

1.22e-04189604ee4c1d930534788a7759d92dc8ff9c62e6ee2301
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A TLE1 KCNJ16 ARID5B

1.25e-04190604bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A TLE1 KCNJ16 ARID5B

1.25e-04190604b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCelldroplet-Limb_Muscle-nan-3m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 CD6 ABCB9 RUNX3

1.25e-04190604d00fa8eda2454c5f9eddfb0e08913a68bb0bd8fc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD84 XYLT1 CD6 RUNX3

1.25e-0419060407ea0578ca0561077557203ae660530f53fc4067
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD84 XYLT1 CD6 RUNX3

1.25e-041906045b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 COL12A1 PODN ADGRG4

1.27e-041916042c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellControl-Lymphoid-T_Cytotoxic|Control / Disease state, Lineage and Cell class

CD6 ATF7IP RUNX3 MPP7

1.27e-0419160403b5c5e0941c3402ab3f48cbf3da2a027d110421
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NPIPB15 ABCB9 HIPK2 DDOST

1.27e-041916043df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

CD6 ATF7IP RUNX3 MPP7

1.30e-04192604064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD84 CD6 ATF7IP RUNX3

1.30e-04192604ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCell(3)_Chondrocytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 SDK2 COL12A1 RUNX3

1.30e-041926045d2b4830d025d3dbdf5623ce1c28d1036e1984a8
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD84 CD6 ATF7IP RUNX3

1.30e-041926046779b0294bb058e748e22b795b6a381c4add37e9
ToppCellCOPD-Lymphoid-T_Cytotoxic|COPD / Disease state, Lineage and Cell class

CD6 ATF7IP RUNX3 MPP7

1.33e-0419360458e94fe2e89cdafc6974938f97a4c162061a437d
ToppCellLA|World / Chamber and Cluster_Paper

XYLT1 COL12A1 PODN PRG4

1.33e-04193604d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

TLE1 HIPK2 RUNX3 MEX3C

1.35e-04194604c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TLE1 ATF7IP ARID5B HIPK2

1.35e-04194604f0c113edb706d53792892115b67277a285219942
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD84 XYLT1 CD6 RUNX3

1.35e-04194604633fe72cc8a489abde12428e326478409ca03263
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD84 XYLT1 CD6 RUNX3

1.35e-0419460487a86df0b542f287b0b20f4a4b1a37002271671d
ToppCellControl-Lymphoid|Control / Disease state, Lineage and Cell class

CD6 ATF7IP RUNX3 MPP7

1.35e-04194604d5b124f15c953eeb7e8e990df44d7fa466f2b31f
ToppCell10x5'-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

TLE1 HIPK2 RUNX3 MEX3C

1.38e-04195604c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCellmedial-Hematologic-CD8+_Memory/Effector_T-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD84 CD6 RUNX3 SSTR3

1.41e-04196604252e15a4ea54d872c5b910711941dcdf359c0492
ToppCellmedial-Hematologic-CD8+_Memory/Effector_T|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD84 CD6 RUNX3 SSTR3

1.41e-04196604caef28955269f4f6fb323a74b6b73cff8db11272
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TLE1 HIPK2 RUNX3 MEX3C

1.41e-04196604cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCellmedial-2-Hematologic-CD8+_Memory/Effector_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD84 CD6 RUNX3 SSTR3

1.41e-04196604e401d1683a13f2636e8fc0e22428a6a3653a1521
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-T_reg|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 CD6 RUNX3 SSTR3

1.41e-04196604c0028307cf5dddfc4b5db1445fa83b74019a20bd
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD6 ATF7IP ARID5B MPP7

1.41e-041966044a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Tfh|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD84 CD6 ARID5B PRG4

1.44e-04197604144ca23372b3265007a1e508e48d320581cf5695
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 SDK2 COL12A1 RUNX3

1.44e-04197604a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD84 XYLT1 CD6 RUNX3

1.44e-0419760461ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 XYLT1 CD6 RUNX3

1.49e-04199604fbdde57dd88656621801e65ee2818251588f3874
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 XYLT1 CD6 RUNX3

1.52e-04200604dfdfad881c114e1bc9a64b411e1b00fb37cc859b
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-CD4+_T_naive|ICU-SEP / Disease, condition lineage and cell class

SDK2 ARID5B SSTR3 PRG4

1.52e-04200604134a5e0cc46264b0aef69d4fd59f38fc7c334f69
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 XYLT1 CD6 RUNX3

1.52e-0420060466fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 XYLT1 CD6 RUNX3

1.52e-04200604f7a9d8b99de19e9842422bada348d940e0863645
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 PODN PRG4 PXK

1.52e-042006043e0041c04e42a47257517dae8707a6454570c256
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 TNFAIP8L2 AOC1 RUNX3

1.52e-042006040cb6e65f9efe1d4fd18b8ef4333cc39956cafdad
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

XYLT1 PODN FRMPD3

2.06e-048560367336aa7ec02b64595ce7d5222d43cead92eb52e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Striatum / BrainAtlas - Mouse McCarroll V32

XYLT1 PODN FRMPD3

2.06e-0485603a7a5d82924cd4a41ab87b1abf13143635882a4b2
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

XYLT1 PODN FRMPD3

2.06e-048560386c5d71b66ff55c44d2d457865dda72e07e5ec53
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb-Excitatory_Neuron.Slc17a7-Slc17a6.Rorb-Pcdh20_(Layer_5a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IGFN1 CD6 TMPRSS7

2.52e-04916031fa597c5fa4523b18fa386ee19237b82778bb1cb
ToppCellCOVID-19-Heart-Fib_+_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

IGFN1 COL12A1 PRG4

4.63e-04112603d00ee6b19e41a35450681fe676885983536d6292
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IGFN1 CD6 TMPRSS7

5.13e-041166039c92e714e210a2f29a9e228653d4c990ec643c72
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SERPINA11 COL12A1 PODN

7.48e-04132603893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 COL12A1 PODN

7.81e-041346036d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCellLA-10._Endothelium_II|LA / Chamber and Cluster_Paper

NPIPB7 VWF RUNX3

7.81e-04134603048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD84 DSG3 LRCH3

7.98e-041356039f9d0787a2e99207a9caa88a85565189ab8b940a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

SDK2 CD6 TMPRSS7

8.50e-04138603b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellCerebellum-Hematopoietic-MICROGLIA|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-0413960375cca1e6c1af289987d5d98455e9c6db81ecdd64
ToppCellCerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-04139603a077ce50f6d6746d80de35abed5b6dc35b1145b9
ToppCellCerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-04139603de34e2f51f6fda638357abb662c111a20b83e70b
ToppCellCerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-041396030ae117308bd10d3a7d2688794c69dc5a31cfca5f
ToppCellCerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-04139603fac6a3100a277efa1db250e0c576be1a0c901e6d
ToppCellCerebellum-Hematopoietic|Cerebellum / BrainAtlas - Mouse McCarroll V32

CD84 TNFAIP8L2 RUNX3

8.68e-041396033913c3828ad4cb5c71380519d0cf5f195e53c51d
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD84 TNFAIP8L2 RUNX3

9.05e-041416034a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD84 XYLT1 TNFAIP8L2

9.81e-04145603ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFAIP8L2 CD6 ABCB9

9.81e-04145603a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD84 XYLT1 TNFAIP8L2

9.81e-041456032beb4ea3838796c580076ab7769de877a3a0552c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2|TCGA-Pancreas / Sample_Type by Project: Shred V9

CACNA1B CASKIN1 F7

1.00e-03146603bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

CACNA1B CASKIN1 F7

1.00e-0314660372c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCellP15-Hematopoietic|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD84 TNFAIP8L2 CD6

1.00e-031466032b3e6ff6069573ee213000aeab5de9a33afc1a99
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

CD84 NWD1 CD6

1.04e-03148603db046a02a00829910bf9d7dbda068e730aa78f00
ToppCellfacs-Skin-nan-18m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 RUNX3 F7

1.06e-0314960323a1b95c12f2e3708dc003e13fab423e89821f11
ToppCellfacs-Skin-nan-18m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 RUNX3 F7

1.06e-03149603c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|367C / Donor, Lineage, Cell class and subclass (all cells)

SERPINA11 TLE1 MPP7

1.06e-03149603f18bddc84b064f3d57a1281d5172c404d87f25da
ToppCellCOVID-19_Severe-B_cell|World / disease group, cell group and cell class

NPIPB15 DSG3 TLE1

1.06e-031496039a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCellfacs-Skin-nan-18m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD84 RUNX3 F7

1.06e-03149603bb18a18b891af85849b9658d774053f839c9a8e1
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

KAT7 VWA8 PXK

1.06e-0314960341f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD84 ATF7IP RUNX3

1.08e-03150603207fc230d7721149c7afc7970dd56817f52801d8
Diseasedyslexia

XYLT1 PPP2R3A PTPN21 HEATR5B

3.15e-04162594EFO_0005424
DiseaseS-adenosylhomocysteine measurement

CACNA1B VWA8

5.24e-0417592EFO_0010531
Diseaseage at onset, Parkinson disease

DSG3 QSER1

5.89e-0418592EFO_0004847, MONDO_0005180
Diseasecoagulation factor measurement

VWF F7

7.30e-0420592EFO_0004634
Diseaserespiratory failure, COVID-19

TYK2 HLA-DRB3

1.54e-0329592EFO_0009686, MONDO_0100096
DiseaseDrug habituation

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0013170
DiseaseSubstance-Related Disorders

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0236969
DiseaseDrug abuse

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0013146
DiseaseDrug Use Disorders

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0013222
DiseaseDrug Dependence

XYLT1 TMPRSS7 MPP7

1.60e-03115593C1510472
DiseaseSubstance Dependence

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0038580
DiseaseSubstance Use Disorders

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

XYLT1 TMPRSS7 MPP7

1.60e-03115593C0029231
DiseasePrescription Drug Abuse

XYLT1 TMPRSS7 MPP7

1.60e-03115593C4316881
DiseaseSubstance abuse problem

XYLT1 TMPRSS7 MPP7

1.64e-03116593C0740858

Protein segments in the cluster

PeptideGeneStartEntry
SRTVTRYPANSIVVV

BRI3

61

O95415
TYRVHTPVSIQLVTS

ADGRG4

1236

Q8IZF6
RHRVVQPTLEQTQYS

AOC1

546

P19801
YVSSLTSQSHPLRRV

CACNA1B

2296

Q00975
VVVRHPLSNQVVVYT

ATP10D

781

Q9P241
QFVHAVVNRIIPTTS

NWD1

1471

Q149M9
NVPSIVHSQVYRSSK

QSER1

351

Q2KHR3
PVALTTFYNSQRHRV

CD6

496

P30203
HQSVISRYRVQSTPV

DSG3

356

P32926
SRYRVQSTPVTIQVI

DSG3

361

P32926
LSYNRITSPQVHRDA

PODN

411

Q7Z5L7
PYATVQRRVGRSHSV

CASKIN1

906

Q8WXD9
AYSTRRVTRSQQQPT

KAT7

71

O95251
TTIPVCYRNLRHLQT

LRCH3

231

Q96II8
RTGSHRRQQAYITPT

HIPK2

1051

Q9H2X6
LEHYRVQTQQTGTVR

FEM1B

66

Q9UK73
YGVTVPHTTRARRSQ

MPP7

396

Q5T2T1
VNTDPVSRYTQQLRH

NOD1

121

Q9Y239
TPVINSLAVYRHRET

NPIPB7

21

O75200
TQVSVRPLQHTQYER

DDOST

406

P39656
SYNEKTPRIVVSRSH

BPNT2

231

Q9NX62
TPVINSLAVYRHRET

NPIPB15

21

A6NHN6
RLVVSTVNHYSSVVI

PPP2R3A

6

Q06190
YISSSNPDLITRRVH

PTPN21

586

Q16825
TQRHVKSPRTYSEIT

PCDHAC2

691

Q9Y5I4
ESFTVQRRVHPQVTV

HLA-DRB3

116

P79483
RRVPAEVSNTHQNSY

CEFIP

196

Q711Q0
PRATQTHVEAVYSRR

HEATR5B

341

Q9P2D3
TPYTIENSSHRRAIL

BFAR

226

Q9NZS9
RVQISLVQYSRDPHT

COL12A1

476

Q99715
ALHIYITVSATRPSQ

FRMPD3

311

Q5JV73
IVFRLQTHTTPQIYT

CASC2

46

Q8IU53
QYSPTARIHASQAVV

CADM4

221

Q8NFZ8
TVNVTHRPVTQVTTR

ATF7IP

1036

Q6VMQ6
AYVRSAPSRVQALHT

DENND4B

781

O75064
QYINTISSLRHIRVT

IGFN1

211

Q86VF2
HIYLTVRNPNIVSSS

FSHR

551

P23945
NRTNTRVTHYLPNVT

SDK2

936

Q58EX2
VHISVYRVRNLSNPA

PRPF3

541

O43395
VFTNPTQVATYHRAI

RUNX3

156

Q13761
MQAVTRNYITHPRVT

ATP6V1B1

26

P15313
VYAVVSALQSSPIHR

RGL2

351

O15211
IYVVLRHTASPSVTN

SSTR3

66

P32745
QSRRVAQVIIPSTYV

F7

281

P08709
SRPLQVNTADHRIYS

FAF2

66

Q96CS3
RIQQQTHTYIVTPSR

MEX3C

351

Q5U5Q3
APVVTVTHRNYYERI

CD84

71

Q9UIB8
RAIGPSQTHTIRIQY

PRG4

1306

Q92954
SQTHTIRIQYSPARL

PRG4

1311

Q92954
FTYRTRPHTQVLQNV

ABCB9

511

Q9NP78
VSRPSVIQHVQSFRS

ARID5B

746

Q14865
VVCAVTISNPTRHVY

TLE1

486

Q04724
VLQVSRQYSNVRVTP

XYLT1

371

Q86Y38
SKEYTHSRPQAQRVI

TNFAIP8L2

46

Q6P589
HPFVRSSVIVRSQTF

WWC2

991

Q6AWC2
RIQHTVTASVRLSYG

VWF

481

P04275
PVRRIVVHEYYNSQT

TMPRSS7

676

Q7RTY8
AYHRITPTITNFALR

SERPINA11

46

Q86U17
TSHQSRSSYVPREIL

KCNJ16

291

Q9NPI9
QSHTEYIIRVQRGIS

PXK

31

Q7Z7A4
VVRLPETVHTAVRYT

TNPO3

466

Q9Y5L0
PREYIQLHRDTTVQT

VWA8

801

A3KMH1
PTALHLRYQTSQERV

USP32

1201

Q8NFA0
STSHPYRLILTVAQR

TYK2

476

P29597