Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCHDCT2

CHD5 CHD3

3.14e-053612PF08074
DomainCHDNT

CHD5 CHD3

3.14e-053612PF08073
DomainDUF1086

CHD5 CHD3

3.14e-053612IPR009462
DomainDUF1087

CHD5 CHD3

3.14e-053612IPR009463
DomainCHD_N

CHD5 CHD3

3.14e-053612IPR012958
DomainCHD_C2

CHD5 CHD3

3.14e-053612IPR012957
DomainDUF1087

CHD5 CHD3

3.14e-053612PF06465
DomainDUF1086

CHD5 CHD3

3.14e-053612PF06461
DomainDUF1087

CHD5 CHD3

3.14e-053612SM01147
DomainDUF1086

CHD5 CHD3

3.14e-053612SM01146
DomainDZF

STRBP ZFR

1.04e-045612SM00572
DomainDZF_dom

STRBP ZFR

1.04e-045612IPR006561
DomainDZF

STRBP ZFR

1.04e-045612PF07528
DomainDZF

STRBP ZFR

1.04e-045612PS51703
DomainZINC_PROTEASE

RNPEP ADAMTS1 MMP27 MMP9

2.96e-0498614PS00142
DomainPept_M10A_Zn_BS

MMP27 MMP9

1.07e-0315612IPR021158
DomainHemopexin_CS

MMP27 MMP9

1.38e-0317612IPR018486
DomainPG_binding_1

MMP27 MMP9

1.92e-0320612PF01471
DomainPeptidoglycan-bd-like

MMP27 MMP9

1.92e-0320612IPR002477
DomainMetalloPept_cat_dom

ADAMTS1 MMP27 MMP9

2.36e-0381613IPR024079
Domain-

ADAMTS1 MMP27 MMP9

2.36e-03816133.40.390.10
DomainHemopexin-like_dom

MMP27 MMP9

2.54e-0323612IPR000585
DomainHemopexin-like_repeat

MMP27 MMP9

2.54e-0323612IPR018487
DomainM10A_MMP

MMP27 MMP9

2.54e-0323612IPR033739
DomainHemopexin

MMP27 MMP9

2.54e-0323612PF00045
DomainHEMOPEXIN

MMP27 MMP9

2.54e-0323612PS00024
Domain-

MMP27 MMP9

2.54e-03236122.110.10.10
DomainHEMOPEXIN_2

MMP27 MMP9

2.54e-0323612PS51642
DomainHX

MMP27 MMP9

2.54e-0323612SM00120
DomainPept_M10A

MMP27 MMP9

2.54e-0323612IPR021190
DomainChromo_domain

CHD5 CHD3

2.77e-0324612IPR023780
DomainPeptidase_M10

MMP27 MMP9

2.77e-0324612PF00413
DomainChromo

CHD5 CHD3

3.24e-0326612PF00385
DomainHECT

UBE3A TRIP12

3.49e-0327612PF00632
DomainHECTc

UBE3A TRIP12

3.49e-0327612SM00119
DomainHECT_dom

UBE3A TRIP12

3.49e-0327612IPR000569
DomainHECT

UBE3A TRIP12

3.49e-0327612PS50237
DomainCHROMO_1

CHD5 CHD3

3.76e-0328612PS00598
DomainCHROMO_2

CHD5 CHD3

3.76e-0328612PS50013
DomainZnMc

MMP27 MMP9

4.02e-0329612SM00235
DomainPeptidase_Metallo

MMP27 MMP9

4.02e-0329612IPR006026
DomainSNF2_N

CHD5 CHD3

4.89e-0332612IPR000330
DomainChromodomain-like

CHD5 CHD3

4.89e-0332612IPR016197
DomainSNF2_N

CHD5 CHD3

4.89e-0332612PF00176
DomainARM-type_fold

RNPEP EIF4G3 PPP6R2 TRIP12 ITPR1

4.96e-03339615IPR016024
DomainChromo/shadow_dom

CHD5 CHD3

5.19e-0333612IPR000953
DomainCHROMO

CHD5 CHD3

5.19e-0333612SM00298
DomainDNA/RNA_helicase_DEAH_CS

CHD5 CHD3

5.83e-0335612IPR002464
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TMEM132C PRUNE2 MAP1A PPFIBP2 CHD5 YLPM1 ZFR CLINT1 EIF4G3 TRIP12 NOTCH1 MGRN1

1.65e-11430631235044719
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ANKRD29 GABRG2 PDE2A SLK MAP1A RNPEP SACS MYO7A BCLAF1 ARPC1A BRSK2 EWSR1 CHD3 EIF4G3 PPP6R2 RPL7

3.66e-091431631637142655
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SLK MAP1A STRBP BCLAF1 TAF1B YLPM1 ZFR CLINT1 EIF4G3 TRIP12 PLRG1

6.80e-08724631136232890
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SLK MAP1A BCLAF1 YLPM1 ZFR TACC2 CHD3 CLINT1 EIF4G3 PPP6R2 PLRG1 RPL7

9.94e-08934631233916271
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

STRBP BCLAF1 YLPM1 ZFR EWSR1 CHD3 TRIP12

8.22e-0728363730585729
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

SLK ADAMTS1 TAF1B YLPM1 ZFR CLINT1 EIF4G3 PPP6R2 TRIP12 PLRG1 RPL7

1.73e-061005631119615732
Pubmed

Pigmentation-related genes and their implication in malignant melanoma susceptibility.

MYO7A HPS1 MGRN1

2.03e-061463319320733
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SLK STRBP EWSR1 CHD3 PPP6R2 PLRG1 CEMIP2 ITPR1 MGRN1

2.54e-0665063938777146
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

STRBP ZFR EWSR1 CLINT1 TRIP12 PLRG1 RPL7

2.78e-0634063724332808
Pubmed

Macrophage-released ADAMTS1 promotes muscle stem cell activation.

ADAMTS1 NOTCH1

3.23e-06263228939843
Pubmed

Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells.

MMP9 NOTCH1

3.23e-06263227130612
Pubmed

Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16.

MX1 MGRN1

3.23e-0626322422403
Pubmed

MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway.

FOXO4 MMP9

3.23e-06263233238881
Pubmed

Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.

MMP9 NOTCH1

3.23e-06263221723221
Pubmed

Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells.

MMP9 NOTCH1

3.23e-06263226864323
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

CDC42BPA PTPRM MYO7A EWSR1 ITPR1

3.70e-0612863530995482
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

STRBP BCLAF1 ZFR EWSR1 CLINT1 PLRG1

5.45e-0624463629884807
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CDC42BPA EHHADH STRBP BCLAF1 TAF1B YLPM1 EWSR1 CHD3 CLINT1 TRIP12 PLRG1 RPL7

5.56e-061371631236244648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

STRBP TAF1B ZFR TACC2 CHD3 EIF4G3 TRIP12 PLRG1 RPL7

8.85e-0675963935915203
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GABRG2 SACS STRBP BCLAF1 CHD5 TAF1B YLPM1 ZFR CHD3 EIF4G3 TRIP12 BTNL9

9.26e-061442631235575683
Pubmed

Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator.

MMP9 NOTCH1

9.68e-06363219147749
Pubmed

Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia.

JAK1 NOTCH1

9.68e-06363221880637
Pubmed

The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.

ADAMTS1 TBX5

9.68e-06363226208718
Pubmed

miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling.

PDE2A NOTCH1

9.68e-06363234512162
Pubmed

Immunohistochemical expression of Notch1, Jagged1, NF-κB and MMP-9 in colorectal cancer patients and the relationship to clinicopathological parameters.

MMP9 NOTCH1

9.68e-06363226406415
Pubmed

[Expression of Notch1, MMP-2 and MMP-9 and their significance in glioma patients].

MMP9 NOTCH1

9.68e-06363222490851
Pubmed

Notch1 signaling pathway participates in cancer invasion by regulating MMPs in lingual squamous cell carcinoma.

MMP9 NOTCH1

9.68e-06363221993452
Pubmed

Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation.

MYO7A NOTCH1

9.68e-06363234519870
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CDC42BPA SLFN13 BCLAF1 ZFR CLINT1 EIF4G3 TRIP12 RPL7 CEMIP2

1.07e-0577763935844135
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

STRBP BCLAF1 CHD5 YLPM1 ZFR EWSR1 CHD3 RPL7

1.34e-0560563828977666
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SACS STRBP BCLAF1 ARPC1A YLPM1 ZFR EWSR1 CHD3 TRIP12 RPL7

1.45e-051024631024711643
Pubmed

MxA interacts with and is modified by the SUMOylation machinery.

CHD3 PLRG1 MX1

1.61e-052763325447205
Pubmed

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.

CDC42BPA NOTCH1

1.93e-05463217344417
Pubmed

Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.

CHD3 MMP9

1.93e-05463212431981
Pubmed

Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc.

SACS UBE3A

1.93e-05463223671107
Pubmed

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

RPL7 NOTCH1

1.93e-0546327956819
Pubmed

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

MMP9 NOTCH1

1.93e-05463219290049
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

JAK1 SLK RNPEP PTPRM ALG8 CLINT1 GPAT4 NOTCH1 CEMIP2 MGRN1

1.97e-051061631033845483
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SLK STRBP YLPM1 ZFR EWSR1 CHD3 CLINT1 PLRG1

2.31e-0565363833742100
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RNPEP STRBP YLPM1 ZFR EWSR1 EIF4G3 TRIP12 RPL7

2.31e-0565363822586326
Pubmed

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.

ADAMTS1 NOTCH1 TBX5

2.71e-053263331434798
Pubmed

Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration.

MMP9 NOTCH1

3.22e-05563225704809
Pubmed

Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.

FOXO4 NOTCH1

3.22e-05563221653327
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CDC42BPA YLPM1 CHD3 EIF4G3 RPL7

3.36e-0520263524639526
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GABRG2 CDC42BPA MAP1A UBE3A BCLAF1 BRSK2 TACC2 EIF4G3 PPP6R2 ITPR1

3.60e-051139631036417873
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

JAK1 UBE3A BCLAF1 YLPM1 CHD3 PLRG1

3.61e-0534163632971831
Pubmed

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

ADAMTS1 MMP9 TBX5

4.57e-053863318267097
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

CDC42BPA MAP1A PPFIBP2 YLPM1 ZFR CHD3 EIF4G3 TRIP12

5.17e-0573263834732716
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

STRBP BCLAF1 YLPM1 ZFR EWSR1 CHD3 CLINT1 TRIP12 PLRG1

5.31e-0595463936373674
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

JAK1 UBE3A BCLAF1 ZFR EWSR1 PLRG1 RPL7

6.20e-0555163734728620
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CDC42BPA MRS2 SACS BCLAF1 EIF4G3 PPP6R2 PLRG1 GPAT4 RPL7 CEMIP2 ITPR1

6.69e-051487631133957083
Pubmed

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

JAK1 SLK

6.74e-0576322466296
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

BCLAF1 EWSR1 EIF4G3 TRIP12 RPL7

8.39e-0524563521182205
Pubmed

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

MYO7A NOTCH1

8.98e-05863216141228
Pubmed

Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV.

MYO7A HPS1

8.98e-05863215702992
Pubmed

Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death.

MYOM3 CHD3 PPP6R2

1.04e-045063323272104
Pubmed

Nucleolar proteome dynamics.

ARPC1A ZFR EWSR1 CHD3 PLRG1 RPL7

1.12e-0441963615635413
Pubmed

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients.

NOTCH1 TBX5

1.15e-04963234099102
Pubmed

Noncanonical Notch signals have opposing roles during cardiac development.

NOTCH1 TBX5

1.15e-04963234487959
Pubmed

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.

ADAMTS1 NOTCH1

1.15e-04963223095891
Pubmed

Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7.

UBE3A TRIP12

1.15e-0496329575161
Pubmed

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.

MYO7A NOTCH1

1.15e-04963220727173
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

CDC42BPA STRBP BCLAF1 ZFR EWSR1

1.42e-0427463534244482
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

CDC42BPA BCLAF1 ZFR EWSR1 CHD3 TRIP12 PLRG1 RPL7

1.42e-0484763835850772
Pubmed

Expression of signaling components in embryonic eyelid epithelium.

ADAMTS1 NOTCH1

1.44e-041063224498290
Pubmed

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness.

MYO7A NOTCH1

1.44e-041063223589895
Pubmed

Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology.

MAP1A ITPR1

1.44e-041063232675284
Pubmed

Protein phosphatase 1γ isoforms linked interactions in the brain.

YLPM1 TACC2 RPL7

1.55e-045763323080069
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

BCLAF1 ARPC1A YLPM1 ZFR EWSR1 CHD3 RPL7

1.58e-0464163736057605
Pubmed

Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration.

MMP9 NOTCH1

1.76e-041163219724860
Pubmed

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.

ADAMTS1 NOTCH1

1.76e-041163229337306
Pubmed

Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study.

JAK1 MX1

1.76e-041163212447867
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

BCLAF1 ARPC1A YLPM1 ZFR CLINT1 TRIP12 PLRG1

1.89e-0466063732780723
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

STRBP YLPM1 EWSR1 EIF4G3 GPAT4 RPL7

1.91e-0446263631138677
Pubmed

Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.

ADAMTS1 HPS1 MYOM3

1.98e-046263317975119
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

STRBP ZFR EWSR1 PLRG1

2.03e-0415963422751105
Pubmed

Gene variants associated with ischemic stroke: the cardiovascular health study.

ADAMTS1 HPS1 MYOM3

2.08e-046363319023099
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRM PPFIBP2

2.11e-04126329624153
Pubmed

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.

MYO7A NOTCH1

2.11e-041263225535395
Pubmed

Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.

JAK1 MX1

2.49e-041363219434718
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 FAT2 SACS BRSK2 ARHGAP25 PPP6R2

2.70e-0449363615368895
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field.

ITPR1 TBX5

2.90e-041463221382375
Pubmed

Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development.

NOTCH1 TBX5

2.90e-041463219084512
Pubmed

NOX2 Is Critical to Endocardial to Mesenchymal Transition and Heart Development.

NOTCH1 TBX5

2.90e-041463232655758
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRRC8C EWSR1 EIF4G3 PPP6R2 GPAT4 NOTCH1 CEMIP2 ITPR1 MGRN1

3.00e-04120163935696571
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

MYO7A HPS1 ITPR1

3.09e-047263325917818
Pubmed

Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.

MYO7A HPS1

3.34e-041563218715234
Pubmed

Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.

JAK1 MMP9

3.34e-041563217114464
Pubmed

Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.

MYO7A NOTCH1

3.34e-041563227966429
Pubmed

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.

BCLAF1 NOTCH1

3.34e-041563226522984
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD5 CHD3

3.34e-041563235695185
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

MYO7A NOTCH1

3.34e-041563216914494
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE2A SLK UBE3A BCLAF1 YLPM1 ZFR EWSR1 PPP6R2

3.38e-0496363828671696
Pubmed

Maternal nicotine exposure induces congenital heart defects in the offspring of mice.

NOTCH1 TBX5

3.81e-041663235521669
Pubmed

Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families.

MMP27 MMP9

3.81e-041663220484597
Pubmed

Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1.

NOTCH1 TBX5

3.81e-041663231591643
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

STRBP BCLAF1 YLPM1 ZFR EWSR1 TRIP12 PLRG1 RPL7

4.03e-0498963836424410
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

SLK BCLAF1 YLPM1 GPAT4

4.08e-0419163431177093
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

BCLAF1 CHD5 ARPC1A ZFR EWSR1 CLINT1 TRIP12 PLRG1 RPL7

4.18e-04125763936526897
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MAP1A SACS BRSK2 EIF4G3 PPP6R2

4.20e-0434763517114649
InteractionKCTD13 interactions

ANKRD29 GABRG2 PDE2A SLK MAP1A RNPEP SACS MYO7A BCLAF1 ARPC1A BRSK2 EWSR1 CHD3 EIF4G3 PPP6R2 RPL7

3.29e-0613946216int:KCTD13
InteractionCHD4 interactions

SLK STRBP BCLAF1 CHD5 YLPM1 ZFR EWSR1 CHD3 TRIP12 RPL7 NOTCH1 TBX5

2.42e-059386212int:CHD4
InteractionBMI1 interactions

UBE3A STRBP BCLAF1 YLPM1 ZFR EWSR1 CHD3 EIF4G3 PLRG1 RPL7

3.02e-056596210int:BMI1
InteractionNAA40 interactions

SLK MAP1A BCLAF1 YLPM1 ZFR TACC2 CHD3 CLINT1 EIF4G3 PPP6R2 PLRG1 RPL7

3.64e-059786212int:NAA40
GeneFamilyPHD finger proteins|NuRD complex

CHD5 CHD3

3.26e-04124121305
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TMEM132C SACS YLPM1 ITPR1

7.37e-04181414694
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP27 MMP9

1.34e-0324412891
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK1 MYO7A

5.74e-03504121293
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PTPRM MYOM3 SIGLEC16

5.77e-03161413593
GeneFamilyPHD finger proteins

CHD5 CHD3

1.77e-029041288
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

JAK1 SLK SACS MYO7A UBE3A BCLAF1 PHTF2 ZFR ARHGAP25 CHD3 TRIP12 RPL7 NOTCH1 ITPR1

9.49e-0614926314M40023
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#5_top-relative-expression-ranked_500

LRRC8C PDE2A SLK PTPRM MYO7A ARHGAP25 BTNL9

1.48e-06193627DevelopingKidney_e15.5_Endothelial cells_emap-29977_k5_500
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#2_top-relative-expression-ranked_1000

LRRC8C PDE2A SLK RNPEP PTPRM MYO7A ARHGAP25 BTNL9

2.72e-06303628gudmap_developingKidney_e15.5_Endothelial cells_1000_k2
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_k-means-cluster#4_top-relative-expression-ranked_1000

LRRC8C PDE2A SLK PTPRM ARHGAP25 BTNL9 NOTCH1

2.00e-05287627gudmap_kidney_e15.5_SmlBldVes_Tie2_k4_1000
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_500

LRRC8C PDE2A SLK PTPRM MYO7A ARHGAP25 BTNL9

1.25e-04384627DevelopingKidney_e15.5_Endothelial cells_emap-29977_500
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 LRRC8C PDE2A ADAMTS1 MYO7A NOTCH1 CEMIP2

1.08e-081936378084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellfacs-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM ADAMTS1 BTNL9 NOTCH1

3.29e-071946365fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCellfacs-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM ADAMTS1 BTNL9 NOTCH1

3.29e-0719463604df35246287815bdd28adaf885bdb98cf49524e
ToppCellfacs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM ADAMTS1 BTNL9 NOTCH1

3.29e-0719463690928d6c96c6304ae35dcc0275f7889de93da100
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CDC42BPA STRBP BCLAF1 ZFR CLINT1 TRIP12

3.82e-0719963661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TMEM132C PRUNE2 ADAMTS1 TACC2 ITPR1 TBX5

3.94e-0720063687827041663013f5e7273168dc8709d69840e7ce
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

TMEM132C PRUNE2 MAP1A ADAMTS1 TACC2 TBX5

3.94e-0720063602cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

CDC42BPA STRBP ZFR CLINT1 TRIP12

1.54e-06138635817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PRUNE2 SACS ADAMTS1 CHD5 TBX5

4.65e-06173635a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9 NOTCH1

7.16e-06189635f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9 NOTCH1

7.16e-06189635e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9 NOTCH1

7.16e-061896355559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM NOTCH1 CEMIP2

7.34e-0619063538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM NOTCH1 CEMIP2

7.34e-06190635bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM NOTCH1 CEMIP2

7.34e-06190635d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 ADAMTS1 PPFIBP2 ITPR1 TBX5

7.53e-061916357853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell(4)_Endothelial_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

JAK1 PDE2A ADAMTS1 BTNL9 NOTCH1

7.92e-06193635ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

JAK1 PDE2A ADAMTS1 BTNL9 NOTCH1

8.12e-061946354428b472c2042f88eae028b1770767512a515b75
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C SLK MYO7A BTNL9 CEMIP2

8.33e-061956353969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A ADAMTS1 MYO7A BTNL9 CEMIP2

8.54e-0619663581900dcc9451ff6606ec940c16b559d73247590e
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 PDE2A ADAMTS1 NOTCH1 CEMIP2

8.75e-06197635deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 PDE2A ADAMTS1 NOTCH1 CEMIP2

8.75e-06197635a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 UBE3A STRBP CHD5 ITPR1

8.97e-06198635c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 UBE3A STRBP CHD5 ITPR1

8.97e-061986358ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 UBE3A STRBP CHD5 ITPR1

8.97e-061986354ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRM ADAMTS1 BTNL9 NOTCH1 ITPR1

9.19e-06199635fff88d2bba262583bb726900ae01e44954b72eb9
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MAP1A ADAMTS1 PHTF2 TACC2 ITPR1

9.41e-06200635a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 MAP1A ADAMTS1 TACC2 TBX5

9.41e-06200635593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRUNE2 ADAMTS1 TACC2 ITPR1 TBX5

9.41e-062006358988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ADAMTS1 SLFN13 ARHGAP25 EIF4G3 MX1

9.41e-062006352281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

PRUNE2 ADAMTS1 CHD5 TBX5

7.79e-05160634d783d29150033e9181c0e30870070268fed3fd85
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

PRUNE2 SACS ADAMTS1 TBX5

7.98e-0516163464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

PRUNE2 ADAMTS1 TACC2 TBX5

8.78e-05165634531804467601e1ee1f771cffa21501f6d464ae10
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PAPOLB CRIP3 SERPINA7

9.33e-05626339db88da996b9977f5a89afe505cd55e7b5324bc9
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PAPOLB CRIP3 SERPINA7

9.33e-0562633461d280a1b955033186cfc326f9ace85b4a53c54
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADAMTS1 CRIP3 CEMIP2 ITPR1

9.63e-05169634c3a6179a64589a370108fea809b157839347759c
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C PRUNE2 ANKRD29 PDE2A

9.85e-05170634cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C PRUNE2 ANKRD29 PDE2A

9.85e-051706340bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C PRUNE2 ANKRD29 PDE2A

9.85e-05170634516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PRUNE2 PDE2A MMP9 BTNL9

1.10e-0417563484d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PRUNE2 PDE2A MMP9 BTNL9

1.10e-04175634a00c6fa9b33640710dd05a3799031147196f0986
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLK PTPRM NOTCH1 CEMIP2

1.13e-04176634269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9

1.18e-04178634ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 LRRC8C BTNL9 TBX5

1.20e-04179634e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDE2A PTPRM ARHGAP25 CEMIP2

1.20e-04179634d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 LRRC8C BTNL9 TBX5

1.20e-041796349863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 LRRC8C BTNL9 TBX5

1.20e-04179634dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDC42BPA PTPRM ADAMTS1 BTNL9

1.20e-041796342a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRC8C PDE2A PIWIL1 BTNL9

1.23e-04180634755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 CDC42BPA PTPRM CEMIP2

1.28e-04182634c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A PTPRM ADAMTS1 NOTCH1

1.28e-04182634840427d1c23d60482c943ff006b14007ed44d247
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 CDC42BPA PTPRM CEMIP2

1.28e-04182634d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A ADAMTS1 BTNL9

1.28e-041826343b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A ADAMTS1 BTNL9

1.28e-04182634ab5761bf9af439231cd0f487b6467e372672a517
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 GABRG2 CHD5 BRSK2

1.28e-04182634a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 CDC42BPA PTPRM CEMIP2

1.31e-0418363412e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellIPF-Lymphoid-B|IPF / Disease state, Lineage and Cell class

STRBP ARHGAP25 CEMIP2 ITPR1

1.31e-04183634e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM132C MYO7A FOXO4 TBX5

1.31e-04183634dc9602bed3136db91faeffef177006246dc92743
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 CDC42BPA PTPRM CEMIP2

1.34e-04184634087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANKRD29 TACC2 NOTCH1 CEMIP2

1.34e-041846348ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A ADAMTS1 BTNL9 CEMIP2

1.36e-04185634742350093d90f96735dc73e3360cdd749bae63fd
ToppCellCOPD-Lymphoid-B|COPD / Disease state, Lineage and Cell class

STRBP PPFIBP2 ARHGAP25 CEMIP2

1.36e-04185634925e79c35c381dd44ec5fb921dca09ce43140135
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C PRUNE2 ADAMTS1 TBX5

1.36e-04185634e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellCOPD-Lymphoid-B|World / Disease state, Lineage and Cell class

STRBP PPFIBP2 ARHGAP25 CEMIP2

1.36e-0418563422891ed75e25ef30dfa541cb82d85e08ce07e7d9
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE2A PTPRM BTNL9 NOTCH1

1.42e-0418763425efb82afe863a853ecdd781ad89026c993aaa67
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

PRUNE2 MYOM3 TACC2 TBX5

1.45e-041886346d249fe92d51a19da19ec14bb2262d394255d577
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C PRUNE2 ADAMTS1 TBX5

1.45e-041886343177b2c1723268d330d3e9f24f9e24492ace6286
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 PDE2A NWD1 CEMIP2

1.45e-041886340aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

STRBP BTNL9 CEMIP2 ITPR1

1.45e-04188634ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A PTPRM BTNL9 NOTCH1

1.45e-0418863420072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCellfacs-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A PTPRM BTNL9 NOTCH1

1.45e-04188634dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 ADAMTS1 TACC2 TBX5

1.45e-04188634293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAK1 SLFN13 NOTCH1 CEMIP2

1.45e-041886349abd78970bbe4ed03b59a83da63bbd334712f605
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAK1 SLFN13 NOTCH1 CEMIP2

1.45e-04188634f7dc29dfec68236883469e848be5db34f5526d6b
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 ADAMTS1 TACC2 TBX5

1.45e-041886344d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE2A NWD1 PAPOLB NOTCH1

1.45e-04188634524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A PTPRM BTNL9 NOTCH1

1.45e-041886346ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAK1 SLFN13 NOTCH1 CEMIP2

1.45e-041886345ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE2A NWD1 PAPOLB NOTCH1

1.45e-04188634d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellfacs-Heart-LV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9

1.48e-04189634d424d2554595b2304219f7324406b401711af7c2
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

JAK1 PDE2A BTNL9 NOTCH1

1.48e-041896340f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C PRUNE2 ADAMTS1 TBX5

1.48e-041896347ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

TMEM132C PTPRM CEMIP2 ITPR1

1.48e-04189634c81787a8c662db5d7814c583dd64562857629e81
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9

1.48e-04189634393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 FAT2 BRSK2 ITPR1

1.48e-04189634f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellfacs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A PTPRM BTNL9

1.48e-04189634bec57459ad4bab15b2532b57722549fec2e771fb
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 PDE2A NWD1 CEMIP2

1.51e-04190634a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A BTNL9 NOTCH1

1.51e-0419063489d1d686cc683206534e2157554d7d0df5d53497
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

JAK1 PDE2A MYO7A BTNL9

1.51e-041906346b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCellfacs-SCAT-Fat-18m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A PTPRM BTNL9 NOTCH1

1.51e-04190634b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A BTNL9 NOTCH1

1.51e-0419063465ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 PDE2A NWD1 CEMIP2

1.51e-0419063425525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellfacs-SCAT-Fat-18m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A PTPRM BTNL9 NOTCH1

1.51e-04190634ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCellfacs-SCAT-Fat-18m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A PTPRM BTNL9 NOTCH1

1.51e-041906340e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C PRUNE2 ADAMTS1 TBX5

1.54e-0419163408042952431ca1a6fd7dfc13f36eb28643979598
ToppCellfacs-Heart-RV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A BTNL9 NOTCH1

1.54e-0419163484ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A BTNL9 NOTCH1

1.57e-04192634777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PDE2A BTNL9 NOTCH1

1.57e-0419263460a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM BTNL9 NOTCH1

1.57e-041926348f20d3511dcb44445592b17d005a53da0052ae56
ToppCellB_cells-Memory_B_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

STRBP ARHGAP25 BTNL9 ITPR1

1.57e-04192634eef591095921ede098f41a2b81897b18915bb753
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A

PRUNE2 CHD5 BRSK2 ETAA1 SERPINA7 ITPR1 TBX5

1.24e-061986372281_UP
DrugIopamidol [60166-93-0]; Up 200; 5.2uM; PC3; HT_HG-U133A

PRUNE2 MAP1A HPS1 ETAA1 PHTF2 CEMIP2 MX1

1.24e-061986375832_UP
Drugechinosporin

ADAMTS1 MX1

7.54e-062632CID000072542
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

UBE3A PHTF2 ZFR EWSR1 CLINT1 CEMIP2

1.56e-051936364846_DN
DrugEucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

CDC42BPA HPS1 EWSR1 CHD3 PPP6R2 CEMIP2

1.70e-051966363416_DN
DrugGemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A

UBE3A YLPM1 PHTF2 ZFR CHD3 ITPR1

1.70e-051966362113_DN
Diseasetransient cerebral ischemia (biomarker_via_orthology)

JAK1 ADAMTS1 MMP9 NOTCH1 ITPR1

2.03e-05157625DOID:224 (biomarker_via_orthology)
Diseasealkaline phosphatase measurement

JAK1 MAP1A MRS2 ARHGAP25 CHD3 MMP9 EIF4G3 PPP6R2 NOTCH1 ITPR1

4.70e-0510156210EFO_0004533
Diseaseinformation processing speed, response to cranial radiation therapy

PPFIBP2 ZFR ARHGAP25

2.51e-0458623EFO_0004363, EFO_0010950
DiseaseProstatic Neoplasms

JAK1 EHHADH PPFIBP2 EWSR1 CHD3 MMP9 ITPR1

3.04e-04616627C0033578
DiseaseMalignant neoplasm of prostate

JAK1 EHHADH PPFIBP2 EWSR1 CHD3 MMP9 ITPR1

3.04e-04616627C0376358
Diseasecardiotoxicity, response to anthracycline-based chemotherapy

PRUNE2 RPL7

3.89e-0414622EFO_0005257, EFO_1001482
DiseaseHuntington's disease (biomarker_via_orthology)

MMP9 ITPR1

5.11e-0416622DOID:12858 (biomarker_via_orthology)
Diseasegastric ulcer (biomarker_via_orthology)

FOXO4 MMP9

8.89e-0421622DOID:10808 (biomarker_via_orthology)
DiseaseNeurodevelopmental Disorders

BRSK2 TRIP12 ITPR1

1.00e-0393623C1535926
DiseaseCerebral Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0750935
DiseaseIntracranial Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0750936
DiseasePilocytic Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0334583
DiseaseAstrocytoma

MMP9 NOTCH1

1.26e-0325622C0004114
DiseaseJuvenile Pilocytic Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0280783
DiseaseDiffuse Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0280785
DiseaseGrade I Astrocytoma

MMP9 NOTCH1

1.26e-0325622C1704230
DiseaseSubependymal Giant Cell Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0205768
DiseaseMixed oligoastrocytoma

MMP9 NOTCH1

1.26e-0325622C0547065
DiseaseChildhood Cerebral Astrocytoma

MMP9 NOTCH1

1.26e-0325622C0338070
DiseaseGemistocytic astrocytoma

MMP9 NOTCH1

1.37e-0326622C0334581
DiseaseProtoplasmic astrocytoma

MMP9 NOTCH1

1.37e-0326622C0334580
DiseaseFibrillary Astrocytoma

MMP9 NOTCH1

1.37e-0326622C0334582
Diseasepancreatic ductal adenocarcinoma (is_marker_for)

JAK1 PTPRM

1.47e-0327622DOID:3498 (is_marker_for)
DiseaseAnaplastic astrocytoma

MMP9 NOTCH1

1.47e-0327622C0334579
DiseaseMalignant neoplasm of breast

ANKRD29 PDE2A ADAMTS1 STRBP CHD5 TACC2 MMP9 NOTCH1

1.78e-031074628C0006142
DiseaseDrug habituation

SLK EHHADH PIWIL1

1.84e-03115623C0013170
DiseaseSubstance-Related Disorders

SLK EHHADH PIWIL1

1.84e-03115623C0236969
DiseaseDrug abuse

SLK EHHADH PIWIL1

1.84e-03115623C0013146
DiseaseDrug Use Disorders

SLK EHHADH PIWIL1

1.84e-03115623C0013222
DiseaseDrug Dependence

SLK EHHADH PIWIL1

1.84e-03115623C1510472
DiseaseSubstance Dependence

SLK EHHADH PIWIL1

1.84e-03115623C0038580
DiseaseSubstance Use Disorders

SLK EHHADH PIWIL1

1.84e-03115623C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

SLK EHHADH PIWIL1

1.84e-03115623C0029231
DiseasePrescription Drug Abuse

SLK EHHADH PIWIL1

1.84e-03115623C4316881
DiseaseSubstance abuse problem

SLK EHHADH PIWIL1

1.89e-03116623C0740858
Diseaselung disease severity measurement

TMEM132C LRRC8C MMP27

1.99e-03118623EFO_0007744

Protein segments in the cluster

PeptideGeneStartEntry
PTAKAAVEWFDGKDF

EWSR1

421

Q01844
DVFVPGASAWKSAFV

BTNL9

246

Q6UXG8
SASTWEKRGPNKFFF

RNPEP

206

Q9H4A4
KWREFSANNPFKGSS

CHD5

191

Q8TDI0
FKKETPLANAAFWAA

ANKRD29

6

Q8N6D5
FVKWSPLENKFAVGS

ARPC1A

101

Q92747
LADFFSGTWSQGTKK

NWD1

681

Q149M9
EFSKASFGSGPAVEW

ADAMTS1

631

Q9UHI8
DSKNLSVAADKWSFG

JAK1

766

P23458
KAEWSKLFEAPSFFQ

PAPOLB

356

Q9NRJ5
TWFQCKEPKNSSFGF

MMP27

461

Q9H306
TSNFDSDKKWGFCPD

MMP9

376

P14780
QLWFPEGFKVSEASK

NOTCH1

1766

P46531
WASDFKDFQESSPQK

MAP1A

1751

P78559
KSSSDAFFLPSEWEK

M1AP

511

Q8TC57
EEWDKNKSAFPFSDK

CLINT1

186

Q14677
QFWKAAKPGANSTTD

ITPR1

71

Q14643
FSLPSFKIDFSEWKD

MGRN1

171

O60291
ESSPELAKKSWFGNF

BRSK2

511

Q8IWQ3
AFFAERKANKWSTPS

EHHADH

271

Q08426
TFASGSPDNIKQWKF

PLRG1

386

O43660
SPDNIKQWKFPDGSF

PLRG1

391

O43660
AWDPDSSSKGKLTFN

FAT2

1161

Q9NYQ8
PYFKDKGDSNSSAGW

FOXO4

136

P98177
GPWFSKFDEDLATAF

PDE2A

526

O00408
SKWSDPQVFEKSSAG

MRS2

271

Q9HD23
FKEANNFLWPFKLSS

RPL7

201

P18124
EGGFSKWNATNKDPE

PPFIBP2

336

Q8ND30
SKVGSFFDDWNDPSF

ETAA1

571

Q9NY74
KYDPQFGDAFWNSSK

GPAT4

351

Q86UL3
AKWREFSANNPFKGS

CHD3

191

Q12873
FNFKKSGSSPKWTHD

BCLAF1

876

Q9NYF8
WIPDTFFRNSKKADA

GABRG2

146

P18507
FSGNFKPSWTKLFTS

CEMIP2

1326

Q9UHN6
PVFFAEKVSSLGKNW

CRIP3

11

Q6Q6R5
FKAKAFSKSEPGSSW

HPS1

451

Q92902
KPAGFSLDWKGNSFK

SACS

2221

Q9NZJ4
SWSGDPFLKDGSFNS

SLFN13

111

Q68D06
FYKWESSKDPAEQNG

EIF4G3

1546

O43432
AGTSAPEEKGWAKFT

PPP6R2

741

O75170
SIAFGGKVDASWDPK

LRRC72

196

A6NJI9
SFFEGQSAPWDSAKK

PTPRM

906

P28827
GKTFDYNPQFADWSK

PIWIL1

466

Q96J94
GSAFAKAKPESPWTS

PHTF2

96

Q8N3S3
AQPSRWSSNFKDFLK

SLK

256

Q9H2G2
KSLEFTKSGPWESEF

PRUNE2

706

Q8WUY3
SNFLGPTNKFSFDWK

TMEM132C

116

Q8N3T6
FADNKWSVTGKAEPA

TBX5

116

Q99593
TAGKKSPSSFQFNWT

TAF1B

466

Q53T94
PFQKYSWSVTDKEGA

STRBP

336

Q96SI9
DFKKHPFFSGIDWDN

CDC42BPA

336

Q5VT25
ANKPDGSIRWKSFSF

ALG8

221

Q9BVK2
TKLFWFNPSSFETEG

UBE3A

596

Q05086
KNEFWSPSSEAKAGE

ARHGAP25

466

P42331
FKAQWANPFDPSKTE

SERPINA7

206

P05543
KWDDPNFNPFSSTSK

TACC2

2341

O95359
FDQFWSAAKTKGFEV

YLPM1

1941

P49750
AAWTGTTFTKKAPFQ

ZFR

301

Q96KR1
GSSKFDWAARFSPKV

TRIP12

256

Q14669
VFNWAFKKCPAPSFS

SIGLEC16

166

A6NMB1
CSNFWFKFPGSSSKI

LRRC8C

141

Q8TDW0
KKSWDFGAFQSSSAT

MX1

556

P20591
KWPTFGSAFFEVKQT

MYO7A

2106

Q13402
DSSEFQWSKDYKGPL

MYOM3

926

Q5VTT5