Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF1908	MAST2 MAST1	3.13e-06	4	14	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST1	3.13e-06	4	14	2	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST1	3.13e-06	4	14	2	IPR023142
Domain	-	MAST2 MAST1	3.13e-06	4	14	2	1.20.1480.20
Domain	Pkinase_C	MAST2 MAST1	4.42e-04	42	14	2	PF00433
Domain	AGC-kinase_C	MAST2 MAST1	7.85e-04	56	14	2	IPR000961
Domain	AGC_KINASE_CTER	MAST2 MAST1	7.85e-04	56	14	2	PS51285
Domain	S_TK_X	MAST2 MAST1	7.85e-04	56	14	2	SM00133
Domain	PDZ	MAST2 MAST1	4.85e-03	141	14	2	PF00595
Domain	PDZ	MAST2 MAST1	5.33e-03	148	14	2	SM00228
Domain	-	MAST2 MAST1	5.47e-03	150	14	2	2.30.42.10
Domain	PDZ	MAST2 MAST1	5.54e-03	151	14	2	PS50106
Domain	PDZ	MAST2 MAST1	5.62e-03	152	14	2	IPR001478
Domain	Growth_fac_rcpt_	LRP2 FBXL19	5.91e-03	156	14	2	IPR009030
Domain	Leu-rich_rpt	FBXL19 TONSL	1.70e-02	271	14	2	IPR001611
Pubmed	Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.	MAST2 MAST1	5.21e-07	3	15	2	22101766
Pubmed	Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.	MAST2 MAST1	1.04e-06	4	15	2	10404183
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST2 MAST1	1.04e-06	4	15	2	15951562
Pubmed	PDZ-Containing Proteins Targeted by the ACE2 Receptor.	MAST2 MAST1	1.82e-05	15	15	2	34835087
Pubmed	Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.	MAST2 MAST1	2.96e-05	19	15	2	30449657
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	MAST2 MAST1	9.66e-05	34	15	2	30726710
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	MAST2 MAST1	1.08e-04	36	15	2	26053890
Pubmed	Proteomic identification of brain proteins that interact with dynein light chain LC8.	MAST2 MAST1	1.48e-04	42	15	2	14760703
Interaction	SLC9A3 interactions	MAST2 LRP2	6.53e-05	19	13	2	int:SLC9A3
Interaction	DCAF7 interactions	PPP4R1 MAST1 YAF2 FBXL19	6.86e-05	368	13	4	int:DCAF7
Interaction	MAST4 interactions	MAST2 MAST1	1.24e-04	26	13	2	int:MAST4
Cytoband	Ensembl 112 genes in cytogenetic band chr18p11	PPP4R1 C18orf15	2.10e-03	210	15	2	chr18p11
GeneFamily	PDZ domain containing	MAST2 MAST1	4.39e-03	152	12	2	1220
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	MAST2 TONSL AMMECR1	2.68e-05	178	15	3	8b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MAST2 TONSL AMMECR1	2.91e-05	183	15	3	f142b320023eef00b48d4820c46214c9794d37e7
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAST2 TONSL AMMECR1	3.00e-05	185	15	3	e06a784a297f357f3f8e761c24fa70722048ab42
Disease	white matter microstructure measurement	MAST2 LRP2	1.23e-02	390	13	2	EFO_0005674

Protein segments in the cluster

Peptide	Gene	Start	Entry
VRTECGDCHFCRDMK	FBXL19	46	Q6PCT2
SSCVCACVHMCMRDA	OVOS1	16	Q6IE37
MCSRCQGKHRRFEMD	DNAJC14	536	Q6Y2X3
QSHMSCRDMYECSCP	GALK2	366	Q01415
RCIEMMKLCNHLDDC	LRP2	3086	P98164
GMFCSFETRRHLCMV	MAST1	436	Q9Y2H9
CACMRAHRYFLMDCA	C18orf15	156	Q96N68
FCSFDTKRHLCMVME	MAST2	576	Q6P0Q8
MDRTLHKIKCRMECC	STARD10	61	Q9Y365
RFCEMCCDCRMFHVR	PPP4R1	216	Q8TF05
SRKMVVSAEMCCFCF	AMMECR1	121	Q9Y4X0
CAHTMRKRFMESECC	TONSL	231	Q96HA7
RNSAEAFKCMMCDVR	YAF2	31	Q8IY57
ECSECRKAFCEMSHL	ZNF630	376	Q2M218
HMMFDEDRCECVCKT	VEGFD	261	O43915
SMVHMQEKSFRCDTC	ZNF284	306	Q2VY69