Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1E KCNJ18 KCNH4 KCNJ12

1.11e-04152334GO:0022843
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1E KCNJ18 KCNH4 KCNJ12

2.22e-04182334GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1E KCNJ18 KCNH4 KCNJ12

2.32e-04184334GO:0022832
GeneOntologyMolecularFunctionnuclear vitamin D receptor binding

NCOA6 SNW1

3.99e-0418332GO:0042809
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNJ18 KCNH4 KCNJ12

6.32e-04102333GO:0005249
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNJ18 KCNJ12

9.75e-0428332GO:0005242
GeneOntologyMolecularFunctionpotassium channel activity

KCNJ18 KCNH4 KCNJ12

1.22e-03128333GO:0005267
GeneOntologyMolecularFunctiongated channel activity

CACNA1E KCNJ18 KCNH4 KCNJ12

2.15e-03334334GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1E KCNJ18 KCNH4 KCNJ12

2.36e-03343334GO:0005261
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNJ18 KCNH4 KCNJ12

2.61e-03167333GO:0015079
GeneOntologyMolecularFunctionglycolipid binding

CEL PIGK

2.97e-0349332GO:0051861
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA6 SNW1

3.72e-0355332GO:0042974
GeneOntologyMolecularFunctioncysteine-type peptidase activity

CYLD PIGK OTUD7A

3.86e-03192333GO:0008234
GeneOntologyMolecularFunctionisomerase activity

PUS1 PIGK PPIL6

3.86e-03192333GO:0016853
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

PUS1 NCOA6

4.56e-0361332GO:0030374
DomainK_chnl_inward-rec_Kir2.2

KCNJ18 KCNJ12

3.03e-062332IPR003272
DomainK_chnl_inward-rec_Kir_N

KCNJ18 KCNJ12

9.07e-063332IPR013673
DomainIRK_N

KCNJ18 KCNJ12

9.07e-063332PF08466
DomainFH2

FMN2 DAAM2

3.13e-0415332PS51444
DomainFH2_Formin

FMN2 DAAM2

3.13e-0415332IPR015425
DomainFH2

FMN2 DAAM2

3.13e-0415332PF02181
DomainFH2

FMN2 DAAM2

3.13e-0415332SM00498
DomainK_chnl_inward-rec_Kir_cyto

KCNJ18 KCNJ12

3.58e-0416332IPR013518
DomainIRK

KCNJ18 KCNJ12

3.58e-0416332PF01007
Domain-

KCNJ18 KCNJ12

3.58e-04163322.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ18 KCNJ12

3.58e-0416332IPR016449
Pubmed

TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma.

CYLD TRAF3

8.73e-07233228295222
Pubmed

Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.

KCNJ18 KCNJ12

8.73e-07233215705530
Pubmed

Molecular cloning and functional expression of cDNA encoding a second class of inward rectifier potassium channels in the mouse brain.

KCNJ18 KCNJ12

2.62e-0633328083233
Pubmed

The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.

KCNJ18 KCNJ12

2.62e-06333211410627
Pubmed

Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.

KCNJ18 KCNJ12

2.62e-06333217640933
Pubmed

Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.

KCNJ18 KCNJ12

2.62e-06333210904001
Pubmed

Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11.

KCNJ18 KCNJ12

5.23e-0643328921409
Pubmed

Metastasis suppressor microRNA-335 targets the formin family of actin nucleators.

FMN2 DAAM2

5.23e-06433224223803
Pubmed

Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.

KCNJ18 KCNJ12

5.23e-06433220798526
Pubmed

A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction.

KCNJ18 KCNJ12

5.23e-06433232990585
Pubmed

Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels.

KCNJ18 KCNJ12

8.72e-06533216177047
Pubmed

Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.

KCNJ18 KCNJ12

1.31e-0563329529344
Pubmed

The inward rectifier potassium channel family.

KCNJ18 KCNJ12

1.31e-0563327580148
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 CYLD FMN2 NHSL1 NCOA6 KLHDC2 OTUD7A

1.35e-0586133736931259
Pubmed

Functional proteomics mapping of a human signaling pathway.

DAZAP2 NCOA6 MGAT1 FBN2 RBM19 ACOX3

1.76e-0559133615231748
Pubmed

Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.

KCNJ18 KCNJ12

2.44e-05833227930290
Pubmed

A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.

KCNJ18 KCNJ12

3.91e-051033214960569
Pubmed

A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).

KCNJ18 KCNJ12

6.77e-051333210049592
Pubmed

Expression of multiple formins in adult tissues and during developmental stages of mouse brain.

FMN2 DAAM2

7.89e-051433226272686
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

FMN2 NHSL1 SNW1 RPL4

8.37e-0524533435652658
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

DOK6 MGAT1 KLHDC2 PIGK

1.25e-0427233418187620
Pubmed

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.

KCNJ18 KCNJ12

1.32e-041833221511879
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

RALGAPA1 TRAF3 RPS24 RPL4

2.71e-0433333432665550
Pubmed

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

DAAM2 RPS24 KLHDC2 RPL4

2.81e-0433633431253590
Pubmed

Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.

KCNJ18 KCNJ12

3.02e-042733217273973
Pubmed

Human transcription factor protein interaction networks.

CYLD NCOA6 TRAF3 RPS24 FBN2 SNW1 ACACB

3.25e-04142933735140242
Pubmed

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

CYLD TRAF3

3.99e-043133227307491
Pubmed

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

KCNJ18 KCNJ12

3.99e-043133217473172
Pubmed

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.

CYLD OTUD7A

4.25e-043233233669244
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

CACNA1E RPS24 RPL4 OTUD7A

4.56e-0438233437249651
Pubmed

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.

RPS24 SNW1 RPL4

5.52e-0416933323084401
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

FBN2 SNW1 RPL4

7.07e-0418433332908313
Pubmed

Defining the membrane proteome of NK cells.

RPS24 MGAT1 PIGK RPL4 RBM19 ACOX3

7.21e-04116833619946888
Pubmed

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

RPS24 SNW1 RPL4

7.53e-0418833329721183
Pubmed

Accumulation of NCOA1 dependent on HERC3 deficiency transactivates matrix metallopeptidases and promotes extracellular matrix degradation in intervertebral disc degeneration.

SNW1 ACOX3

7.69e-044333236878279
Pubmed

The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions.

RPS24 RPL4

8.06e-044433230320934
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

PUS1 RPS24 SNW1 RPL4 RBM19

9.20e-0480733522681889
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ18 KCNJ12

1.24e-0416192276
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DOK6 RPL4 KCNJ12

3.78e-05883333a92f76e4db86486cb265301e6056af791a11a63
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYLD CACNA1E KCNH4

2.23e-04160333f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYLD CACNA1E KCNH4

2.27e-04161333ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEL CFAP69 PPIL6

2.39e-041643339e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS24 CEL RPL4

2.95e-0417633312bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS24 CEL RPL4

3.04e-04178333415a02ad14df9deba988990118b00fb84ee524a8
ToppCelllung|World / shred on tissue and cell subclass

SLC46A2 RPS24 RPL4

3.04e-041783337b1e371272328d6b6c3994382d64281ffc737db2
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RPS24 RPL4 KCNJ12

3.15e-041803336c0115d03ec58bc7ae5317bf8906617489975351
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

FMN2 CFAP69 PPIL6

3.15e-04180333bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS24 CEL RPL4

3.20e-04181333cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.20e-041813330c3f469bed108994ed696230e3c30343f7a301d3
ToppCelldroplet-Pancreas-PANCREAS|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS24 CEL RPL4

3.25e-04182333ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCelldroplet-Pancreas-PANCREAS-30m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS24 CEL RPL4

3.25e-04182333cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOK6 DAAM2 FBN2

3.30e-041833338a799807fbf24456a9811e0c64068187940a2f71
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS24 FBN2 RPL4

3.35e-04184333e93633d89a9c54c8d2819f56372815b4ca149f06
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RPS24 MGAT1 ZNF256

3.35e-04184333a902109b04a94770f5f6db5ddc372049f2921d38
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.35e-0418433322c18964818fc9c8f18051f836d718937b0d8d12
ToppCelldroplet-Lung-nan-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RPS24 RPL4

3.41e-04185333d4076294571557c223f5b68244e9c53e1d8f0343
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.46e-0418633373cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.46e-0418633341e03be964044dae690d566bd078dab3d8045eba
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-04187333401be371b32066db926de3415bb4ce9465749dc3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-041873335c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-04187333dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-0418733393c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

JPH2 DOK6 DAAM2

3.52e-0418733386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JPH2 DOK6 DAAM2

3.52e-04187333530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-04187333ae90c263f80c36a410150d499e268d198944a3d9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-041873332b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

JPH2 FBN2 ACACB

3.52e-0418733378cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JPH2 DOK6 DAAM2

3.52e-04187333ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.52e-041873335d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

JPH2 CACNA1E ACOX3

3.57e-041883336d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INTS6L JPH2 DAAM2

3.57e-041883339d384c0934f1461bc37b1f83e0877d7bee2116ee
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.57e-04188333505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INTS6L JPH2 DAAM2

3.57e-04188333340f0e3e65c7a00d82d26621ff37107458bebc41
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JPH2 FMN2 DAAM2

3.57e-04188333879de94924de978478696fc7838e05a4d795b905
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JPH2 FMN2 DAAM2

3.63e-04189333ab7ece0a517499b70b7754720d3e434765363af6
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.63e-04189333784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.63e-0418933337ecbd73408d462b47d7e5611f203143e08a2689
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-0419033378cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-0419033307f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-041903333a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-04190333e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-04190333b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-041903332de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.68e-041903331c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.74e-04191333f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.74e-04191333a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JPH2 DOK6 DAAM2

3.80e-0419233324e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.80e-04192333f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 DAAM2 ACACB

3.80e-04192333705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-IPC_like-IPCs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

DOK6 RPS24 RPL4

3.92e-041943332378a98452f6ec33870eeb994b8b812e9b507f4c
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PUS1 NHSL1 RBM19

3.92e-041943334c40d6b50675eae52c419d69e719a9223df02ae3
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

PUS1 NHSL1 RBM19

3.92e-0419433399a90de637e3babec2131cdd9f05ea965d8a8f30
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-IPC_like|6_mon / Sample Type, Dataset, Time_group, and Cell type.

DOK6 RPS24 RPL4

3.92e-041943337ba0445a486feac18b3a4fd6f2855c102e374e2d
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_2|COVID-19_Severe / Disease condition and Cell class

DAAM2 MGAT1 RPL4

3.92e-041943339a9dd34c2e1da1c67c3d9ba99b329966cb9f41d1
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

JPH2 DOK6 DAAM2

3.92e-041943335e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOK6 DAAM2 FBN2

3.97e-0419533355b4030f078173b0136990fae87b6eaf44c58f33
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOK6 DAAM2 FBN2

3.97e-0419533319347b7e8d3ea67e0fddd948078abcab9d364a2d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

DOK6 NHSL1 RPS24

4.03e-041963339401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellcontrol-Lymphocytic-CD4_T_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYLD RPS24 RPL4

4.03e-041963334f8670257ea6fdf58cb102b4c7dc9ba39bb317ef
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

UBR3 CEL KCNJ12

4.09e-04197333f7ef62d78336812573148f8bfce401877ec4e29c
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FMN2 ACACB ZNF256

4.09e-04197333dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JPH2 DOK6 DAAM2

4.09e-0419733301249bd485a3734de87ae6ed9c749597f39c6335
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

DAAM2 FBN2 CEL

4.16e-04198333196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DAZAP2 RPS24 MGAT1

4.16e-04198333822df797fffbedf63ff8a8d99ea57511ce55f7cf
ToppCellsevere-Lymphocytic-CD4_T_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYLD RPS24 RPL4

4.16e-041983331a9d9fb881ab99b8ebec83339c11ed319fbd7ed3
ToppCell(2)_NK/T-(23)_CD4+_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

CYLD RPS24 RPL4

4.16e-0419833386f16b1ae6f9b6d36a72071af883eeb7fb73cc2e
ToppCellmild-Lymphocytic-CD4_T_cells_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYLD RPS24 RPL4

4.16e-04198333ed177a75c2a550b2394115777b70d86da4c9c845
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DAZAP2 RPS24 MGAT1

4.16e-041983339b29232c8b4dcbd81f450f47c3f79bf26c8fb583
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JPH2 DOK6 KCNH4

4.22e-04199333b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCellsevere-Myeloid-CD14_Monocytes_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RPS24 MGAT1 RPL4

4.22e-04199333ce07b7c1edfc6e2136dafcf041361b66a52271d3
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-0420033316f468217427921fa18c6d078ffa990eb019b257
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

NHSL1 CACNA1E RPL4

4.28e-0420033319055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellmild-Lymphocytic-CD4_T_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYLD RPS24 RPL4

4.28e-042003336686e89872fd6c8b77d21992d999a9bcf55f9a2a
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-04200333941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

JPH2 DOK6 DAAM2

4.28e-0420033312326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOK6 DAAM2 FBN2

4.28e-04200333b5b5a32925f225610fe25a021a742d6397162863
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

NHSL1 DAAM2 ACACB

4.28e-04200333e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-04200333d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-04200333f861509b54185d89931db64da1b9d81986cc7938
ToppCellmLN|World / shred on region, Cell_type, and subtype

DAZAP2 RPS24 RPL4

4.28e-042003339c1617dfde9d9aaa260bbad45b7d0b9caa41e15f
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

JPH2 DOK6 DAAM2

4.28e-04200333362706445edb33b313684efe50b1f44f5f816e67
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-042003330442894c39eec69850c090957a5dc7bcecd21e04
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOK6 DAAM2 FBN2

4.28e-04200333d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOK6 DAAM2 FBN2

4.28e-042003334e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellmLN|World / Region, Cell class and subclass

DAZAP2 RPS24 RPL4

4.28e-04200333d8f76374a61db45a689ad2c338d35609629a3199
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

FMN2 NHSL1 ACACB

4.28e-0420033301819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

DOK6 NHSL1 CACNA1E

4.28e-042003330cb0755a101ec655359d051d6a8807408d727c55
Diseasevolumetric bone mineral density

FMN2 CACNA1E

9.55e-0442322EFO_0007620
Diseaseneutrophil percentage of leukocytes

JPH2 TRAF3 CEL PPIL6

4.11e-03610324EFO_0007990
Diseaselymphocyte percentage of leukocytes

JPH2 TRAF3 CEL PPIL6

5.57e-03665324EFO_0007993
Diseasefibrinogen measurement

SLC46A2 CEL

6.24e-03109322EFO_0004623
Diseasebone fracture

DOK6 FMN2

6.58e-03112322EFO_0003931
Diseasecreatinine measurement, glomerular filtration rate

JPH2 NCOA6

7.15e-03117322EFO_0004518, EFO_0005208

Protein segments in the cluster

PeptideGeneStartEntry
GMQLFGGRFNFNDGT

CACNA1E

621

Q15878
LGQNGLDNGFAMFHK

ACOX3

251

O15254
GGAFLMGSGHGANFL

CEL

126

P19835
KMTGTGTHRGFGFVD

RBM19

866

Q9Y4C8
HSGGGMSLTHNKNFR

INTS6L

456

Q5JSJ4
RSGNIMFHSFGNKQG

ACACB

1671

O00763
GNFMNKGQRGGAYGF

DAAM2

806

Q86T65
QRKGNFFMGGSDGGY

DAZAP2

151

Q15038
GGTYQGQFTNGMRHG

JPH2

126

Q9BR39
HLVTMSGANGFGNGK

KCNJ12

21

Q14500
TMTFGRKGVSHGQFF

MGAT1

311

P26572
QKGQGIAAQMGHFSG

NHSL1

286

Q5SYE7
GHFGRRGQGGMKANN

KCNH4

181

Q9UQ05
GGLVHGKMGRANSAN

OTUD7A

536

Q8TE49
GVLGMANKGRHSNGS

PPIL6

241

Q8IXY8
GGGTHRSGQGAFGNM

RPL4

81

P36578
MTGHGGNGFLKFQDS

PIGK

161

Q92643
MQGNSASGNHFSGHG

NCOA6

836

Q14686
GHGFGSSKMSRAQTF

DOK6

286

Q6PKX4
FGGHHSRGNTNKFYM

KLHDC2

106

Q9Y2U9
GHCVSGMGFNKGQYL

FBN2

2731

P35556
FMSRGVGDKGSSSHN

CYLD

321

Q9NQC7
SFHGTGGRGNKFAQM

CFAP69

466

A5D8W1
MNGGNKTRGQADGFG

FMN2

1501

Q9NZ56
HLVTMSGANGFGNGK

KCNJ18

21

B7U540
GYHGMQRNVGSSQFK

PUS1

96

Q9Y606
NGDGMGKGTHLSLFF

TRAF3

461

Q13114
HCGFMGGLQKNKSTG

RALGAPA1

1851

Q6GYQ0
VGQKHFRSNGGRDMF

ZNF256

141

Q9Y2P7
RTHFGGGKTTGFGMI

RPS24

61

P62847
LFNQSKGMDSGFAGG

SNW1

411

Q13573
GHDFNMFRSQAGGAC

UBR3

156

Q6ZT12
SGHLFKQMAGHSGQG

SLC46A2

191

Q9BY10