Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CEP350 MYH1 AMPD1 MYH4 MYH8 EPS8L2 DST MYH13 MAP1A CENPF IFT74 SYNE1 SPTBN2 CEP57L1 DIAPH1 KIF14 MACF1 ROCK1 JAKMIP2 NOS2 ADCY8

5.54e-0910998621GO:0008092
GeneOntologyMolecularFunctionactin binding

MYH1 MYH4 MYH8 EPS8L2 DST MYH13 MAP1A SYNE1 SPTBN2 DIAPH1 MACF1 NOS2 ADCY8

1.31e-074798613GO:0003779
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 MYH1 MYH4 MYH8 MYH13 MCM8 VWA8 HSPA4L ABCA13 SMC6 WRN KIF14 RNF213 MACF1

3.44e-076148614GO:0140657
GeneOntologyMolecularFunctionactin filament binding

MYH1 MYH4 MYH8 EPS8L2 MYH13 SYNE1 SPTBN2 MACF1

6.11e-06227868GO:0051015
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 MYH1 MYH4 MYH8 MYH13 KIF14

1.20e-05118866GO:0003774
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH4 MYH8 MCM8 VWA8 ABCA13 SMC6 WRN KIF14 RNF213 MACF1

1.97e-054418610GO:0016887
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH4 MYH8 MYH13

2.12e-0538864GO:0000146
GeneOntologyMolecularFunctioncell adhesion molecule binding

EPS15 EPS8L2 DST NLGN4X DSCAM NLGN4Y DOCK9 SPTBN2 MACF1 NOS2 GOLGA3

5.15e-055998611GO:0050839
GeneOntologyMolecularFunctionmicrotubule binding

CEP350 DST MAP1A CENPF CEP57L1 KIF14 MACF1 JAKMIP2

5.47e-05308868GO:0008017
GeneOntologyMolecularFunctiontubulin binding

CEP350 DST MAP1A CENPF IFT74 CEP57L1 KIF14 MACF1 JAKMIP2

9.39e-05428869GO:0015631
GeneOntologyMolecularFunctioncalmodulin binding

MYH1 MYH4 MYH8 MYH13 NOS2 ADCY8

4.77e-04230866GO:0005516
GeneOntologyMolecularFunctioncadherin binding

EPS15 EPS8L2 DOCK9 SPTBN2 MACF1 NOS2 GOLGA3

6.51e-04339867GO:0045296
GeneOntologyMolecularFunctionmismatch repair complex binding

MCM8 WRN

9.83e-0411862GO:0032404
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYH4 MYH8 MCM8 VWA8 ABCA13 SMC6 WRN KIF14 RNF213 MACF1

1.81e-037758610GO:0017111
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN4X NLGN4Y

2.12e-0316862GO:0042043
GeneOntologyMolecularFunctionchloride ion binding

NLGN4X NLGN4Y

2.12e-0316862GO:0031404
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

STX19 EPS15 SNPH NLGN4X ABCA13 NLGN4Y SYNE1 SPTBN2 DIAPH1 ROCK1

9.02e-073218610GO:0099003
GeneOntologyBiologicalProcesssynaptic vesicle cycle

STX19 SNPH NLGN4X ABCA13 NLGN4Y SPTBN2 DIAPH1 ROCK1

1.45e-05264868GO:0099504
GeneOntologyBiologicalProcessmale mating behavior

NLGN4X HDAC4 NLGN4Y

3.07e-0515863GO:0060179
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

NLGN4X ABCA13 NLGN4Y DIAPH1 ROCK1

5.08e-0596865GO:0048488
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4X NLGN4Y

5.14e-053862GO:0002124
GeneOntologyBiologicalProcesspresynaptic endocytosis

NLGN4X ABCA13 NLGN4Y DIAPH1 ROCK1

6.79e-05102865GO:0140238
GeneOntologyBiologicalProcesssynaptic vesicle recycling

NLGN4X ABCA13 NLGN4Y DIAPH1 ROCK1

1.02e-04111865GO:0036465
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4X NLGN4Y

1.03e-044862GO:0008049
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

CEP350 EVI5 DNHD1 EPS8L2 RPGRIP1L HDAC4 CCDC42 IFT74 SYNE1 ROCK1 CFAP43

1.05e-046708611GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

CEP350 EVI5 DNHD1 EPS8L2 RPGRIP1L HDAC4 CCDC42 IFT74 SYNE1 ROCK1 CFAP43

1.27e-046858611GO:0030031
GeneOntologyBiologicalProcesscadmium ion transport

SLC39A14 SLC30A1

2.55e-046862GO:0015691
GeneOntologyBiologicalProcesscadmium ion transmembrane transport

SLC39A14 SLC30A1

2.55e-046862GO:0070574
GeneOntologyBiologicalProcesscerebellum development

RPGRIP1L NLGN4X NLGN4Y SPTBN2 KIF14

2.91e-04139865GO:0021549
GeneOntologyCellularComponentmyosin complex

MYH1 MYH4 MYH8 MYH13 MYH16 CGNL1

1.65e-0759876GO:0016459
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH4 MYH8 MYH13

4.90e-0716874GO:0005859
GeneOntologyCellularComponentmyofibril

MYH1 MYH4 MYH8 DST MYH13 HDAC4 SYNE1 SCN1A PDE4DIP

2.04e-06273879GO:0030016
GeneOntologyCellularComponentmyosin filament

MYH1 MYH4 MYH8 MYH13

3.31e-0625874GO:0032982
GeneOntologyCellularComponentcontractile muscle fiber

MYH1 MYH4 MYH8 DST MYH13 HDAC4 SYNE1 SCN1A PDE4DIP

3.35e-06290879GO:0043292
GeneOntologyCellularComponentactin cytoskeleton

MYH1 MYH4 MYH8 DST MYH13 HDAC4 SPTBN2 DIAPH1 MACF1 MYH16 CGNL1 ADCY8

4.62e-065768712GO:0015629
GeneOntologyCellularComponentmyosin II complex

MYH1 MYH4 MYH8 MYH13

5.31e-0628874GO:0016460
GeneOntologyCellularComponentsupramolecular fiber

VIM MYH1 MYH4 MYH8 SNPH RPGRIP1L DST MYH13 HDAC4 MAP1A SYNE1 SCN1A PDE4DIP CEP57L1 DIAPH1 KIF14 MACF1

6.12e-0611798717GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

VIM MYH1 MYH4 MYH8 SNPH RPGRIP1L DST MYH13 HDAC4 MAP1A SYNE1 SCN1A PDE4DIP CEP57L1 DIAPH1 KIF14 MACF1

6.69e-0611878717GO:0099081
GeneOntologyCellularComponentmicrotubule organizing center

CEP350 EVI5 VIM EPS8L2 RPGRIP1L CCDC42 CENPF IFT74 PDE4DIP CEP57L1 WRN DIAPH1 ROCK1 BIRC6

2.48e-059198714GO:0005815
GeneOntologyCellularComponentcentrosome

CEP350 EVI5 EPS8L2 RPGRIP1L CCDC42 CENPF IFT74 PDE4DIP CEP57L1 WRN DIAPH1 BIRC6

8.06e-057708712GO:0005813
GeneOntologyCellularComponentsarcomere

MYH1 MYH4 MYH8 DST HDAC4 SYNE1 SCN1A

8.13e-05249877GO:0030017
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4X NLGN4Y

1.02e-044872GO:0098983
GeneOntologyCellularComponenttype III intermediate filament

VIM DST

2.54e-046872GO:0045098
GeneOntologyCellularComponentexcitatory synapse

NLGN4X NLGN4Y SPTBN2 ADCY8

1.04e-03107874GO:0060076
GeneOntologyCellularComponentsymmetric synapse

NLGN4X NLGN4Y

1.30e-0313872GO:0032280
GeneOntologyCellularComponentA band

MYH1 DST HDAC4

1.33e-0352873GO:0031672
GeneOntologyCellularComponentmicrotubule

SNPH RPGRIP1L DST MAP1A PDE4DIP CEP57L1 KIF14 MACF1

1.70e-03533878GO:0005874
GeneOntologyCellularComponentcoated vesicle membrane

EPS15 TMED2 APOB GOLGA5 ADCY8

2.05e-03215875GO:0030662
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNHD1 RPGRIP1L DST MAP1A CENPF CFAP43

2.09e-03317876GO:0032838
GeneOntologyCellularComponentpostsynaptic density

DST NLGN4X MAP1A NLGN4Y MACF1 SLC30A1 ADCY8

2.75e-03451877GO:0014069
GeneOntologyCellularComponentCOPI-coated vesicle membrane

TMED2 GOLGA5

2.80e-0319872GO:0030663
GeneOntologyCellularComponentintercalated disc

MYH1 DST SCN1A

2.87e-0368873GO:0014704
GeneOntologyCellularComponentsynaptic membrane

STX19 SNPH NLGN4X NLGN4Y SYNE1 SCN1A SLC30A1 ADCY8

2.95e-03583878GO:0097060
GeneOntologyCellularComponentglycinergic synapse

NLGN4X NLGN4Y

3.10e-0320872GO:0098690
GeneOntologyCellularComponentspindle

CEP350 EVI5 CENPF SMC6 DIAPH1 KIF14 BIRC6

3.50e-03471877GO:0005819
GeneOntologyCellularComponentasymmetric synapse

DST NLGN4X MAP1A NLGN4Y MACF1 SLC30A1 ADCY8

3.75e-03477877GO:0032279
GeneOntologyCellularComponentcytoplasmic region

DNHD1 RPGRIP1L DST MAP1A CENPF CFAP43

3.92e-03360876GO:0099568
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

VIM SNPH RPGRIP1L DST MAP1A PDE4DIP CEP57L1 DIAPH1 KIF14 MACF1

4.12e-038998710GO:0099513
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

NLGN4X NLGN4Y

4.45e-0324872GO:0098985
DomainMyosin_tail_1

MYH1 MYH4 MYH8 MYH13 CGNL1

1.42e-0818855PF01576
DomainMyosin_tail

MYH1 MYH4 MYH8 MYH13 CGNL1

1.42e-0818855IPR002928
DomainSpectrin/alpha-actinin

SESTD1 DST SYNE1 SPTBN2 MACF1

3.17e-0732855IPR018159
DomainSPEC

SESTD1 DST SYNE1 SPTBN2 MACF1

3.17e-0732855SM00150
DomainMyosin_N

MYH1 MYH4 MYH8 MYH13

5.25e-0715854PF02736
DomainMyosin_N

MYH1 MYH4 MYH8 MYH13

5.25e-0715854IPR004009
DomainMyosin-like_IQ_dom

MYH1 MYH4 MYH8 MYH13

1.47e-0619854IPR027401
Domain-

MYH1 MYH4 MYH8 MYH13

1.47e-06198544.10.270.10
DomainActinin_actin-bd_CS

DST SYNE1 SPTBN2 MACF1

3.31e-0623854IPR001589
DomainSpectrin

DST SYNE1 SPTBN2 MACF1

3.31e-0623854PF00435
DomainACTININ_2

DST SYNE1 SPTBN2 MACF1

3.31e-0623854PS00020
DomainACTININ_1

DST SYNE1 SPTBN2 MACF1

3.31e-0623854PS00019
DomainSpectrin_repeat

DST SYNE1 SPTBN2 MACF1

8.70e-0629854IPR002017
DomainIQ

MYH1 MYH4 MYH8 MYH13 SCN1A

1.78e-0571855PF00612
DomainNLGN4

NLGN4X NLGN4Y

2.05e-052852IPR030025
DomainMyosin_head_motor_dom

MYH1 MYH4 MYH8 MYH13

2.62e-0538854IPR001609
DomainMYOSIN_MOTOR

MYH1 MYH4 MYH8 MYH13

2.62e-0538854PS51456
DomainMyosin_head

MYH1 MYH4 MYH8 MYH13

2.62e-0538854PF00063
DomainMYSc

MYH1 MYH4 MYH8 MYH13

2.62e-0538854SM00242
DomainIQ

MYH1 MYH4 MYH8 MYH13 SCN1A

3.39e-0581855SM00015
DomainIQ_motif_EF-hand-BS

MYH1 MYH4 MYH8 MYH13 SCN1A

5.62e-0590855IPR000048
DomainIQ

MYH1 MYH4 MYH8 MYH13 SCN1A

6.58e-0593855PS50096
DomainNlgn

NLGN4X NLGN4Y

2.03e-045852IPR000460
DomainCH

DST SYNE1 SPTBN2 MACF1

2.19e-0465854SM00033
DomainCH

DST SYNE1 SPTBN2 MACF1

2.91e-0470854PF00307
Domain-

DST MACF1

3.03e-0468523.90.1290.10
DomainGAR

DST MACF1

3.03e-046852PS51460
Domain-

DST MACF1

3.03e-0468523.30.920.20
DomainGAS_dom

DST MACF1

3.03e-046852IPR003108
DomainGAS2

DST MACF1

3.03e-046852PF02187
DomainGAS2

DST MACF1

3.03e-046852SM00243
Domain-

DST SYNE1 SPTBN2 MACF1

3.08e-04718541.10.418.10
DomainCH

DST SYNE1 SPTBN2 MACF1

3.42e-0473854PS50021
DomainCH-domain

DST SYNE1 SPTBN2 MACF1

3.80e-0475854IPR001715
DomainPlectin_repeat

DST MACF1

4.24e-047852IPR001101
DomainPlectin

DST MACF1

4.24e-047852PF00681
DomainPLEC

DST MACF1

4.24e-047852SM00250
DomainP-loop_NTPase

DNHD1 MYH1 MYH4 MYH8 MYH13 MCM8 VWA8 ABCA13 SMC6 WRN KIF14 RNF213

4.42e-048488512IPR027417
DomainCarboxylesterase_B_CS

NLGN4X NLGN4Y

1.55e-0313852IPR019819
DomainCARBOXYLESTERASE_B_2

NLGN4X NLGN4Y

1.80e-0314852PS00941
DomainCOesterase

NLGN4X NLGN4Y

1.80e-0314852PF00135
DomainCarbesteraseB

NLGN4X NLGN4Y

1.80e-0314852IPR002018
DomainPH

PLEKHB2 DOK6 DOCK9 SPTBN2 ROCK1

3.93e-03229855PF00169
DomainAAA+_ATPase

MCM8 VWA8 ABCA13 RNF213

4.23e-03144854IPR003593
DomainAAA

MCM8 VWA8 ABCA13 RNF213

4.23e-03144854SM00382
DomainARM-type_fold

DOCK9 DIAPH1 MROH7 APOB UNC79 IPO11

4.50e-03339856IPR016024
PathwayREACTOME_RND2_GTPASE_CYCLE

KIDINS220 DST KIF14 GOLGA3

3.23e-0543604M41827
PathwayREACTOME_RND2_GTPASE_CYCLE

KIDINS220 DST KIF14 GOLGA3

3.54e-0544604MM15678
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CEP350 VIM EPS15 RPGRIP1L KIDINS220 DST MYH13 DSCAM SMC6 WRN RNF213 APOB CGNL1 SLC39A14 GOLGA5 SLC30A1 BIRC6 GOLGA3

8.88e-13777881835844135
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH4 MYH8 MYH13

5.72e-10688410077619
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH4 MYH8 MYH13

1.33e-09788435210422
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

VIM EPS15 SESTD1 DST HDAC4 DSCAM CENPF SYNE1 SPTBN2 PDE4DIP DIAPH1 MACF1 ROCK1 JAKMIP2 UNC79 GOLGA3

2.37e-09963881628671696
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

DOK6 SNPH MAP1A SPTBN2 DIAPH1 MROH7 KIF14 MACF1 APOB CFAP43 GOLGA3

5.30e-08496881131343991
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH4 MYH13

6.25e-08488310388558
Pubmed

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

MYH1 MYH4 MYH8

6.25e-0848831985022
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST CENPF SYNE1 PDE4DIP CEP57L1 MACF1 CCDC136

1.20e-0715188717043677
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH4 MYH8

1.56e-0758836196357
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH4 MYH8

1.56e-0758833829126
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH4 MYH8

1.56e-07588312919077
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

MYH8 DST SYNE1 MACF1

1.80e-072088421689717
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH4 MYH8

3.11e-0768831728586
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH4 MYH8

3.11e-07688310588881
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AMPD1 MYH8 DST SYNE1 DOCK9 PDE4DIP MED12L MACF1 ZNF407 BIRC6

5.41e-07497881023414517
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH4 MYH8

5.44e-07788316819597
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH1 MYH4 MYH8

8.69e-0788833864153
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

VIM EPS15 DST CENPF IFT74 KIF14 GOLGA5 BIRC6 GOLGA3

1.19e-0641888934709266
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

EPS15 EPS8L2 KIDINS220 DST DOCK9 SPTBN2 MACF1 GOLGA5 SLC30A1 GOLGA3

1.72e-06565881025468996
Pubmed

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

MYH1 MYH4 MYH8

1.85e-061088319506036
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 VIM DST MYH13 SYNE1 MACF1 CGNL1

2.28e-0623488736243803
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CEP350 EPS15 RPGRIP1L DIAPH1 SUGP1 KIF14 RNF213 ROCK1 GOLGA5 SLC30A1 BIRC6

2.48e-06733881134672954
Pubmed

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

MYH1 MYH4 MYH8

2.55e-06118838136524
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN4X NLGN4Y SCN1A

4.40e-061388327050589
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH1 MYH4 MYH8

4.40e-06138838404542
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 MYH4 MYH8

5.58e-061488327184118
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

VIM RPGRIP1L DST ABCA13 ADAMTS20 APOB GOLGA5 CCDC136 SYNCRIP

6.27e-0651388925798074
Pubmed

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts.

DIAPH1 ROCK1

6.33e-06288212021256
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

6.33e-06288211002341
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4X NLGN4Y

6.33e-06288218434543
Pubmed

ROCK and Dia have opposing effects on adherens junctions downstream of Rho.

DIAPH1 ROCK1

6.33e-06288211992112
Pubmed

Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome.

MYH4 MYH8

6.33e-0628828518795
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4X NLGN4Y

6.33e-06288223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4X NLGN4Y

6.33e-06288224855039
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4X NLGN4Y

6.33e-06288237001827
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4X NLGN4Y

6.33e-06288237080762
Pubmed

Growth and muscle defects in mice lacking adult myosin heavy chain genes.

MYH1 MYH4

6.33e-0628829382868
Pubmed

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.

MYH1 MYH4

6.33e-06288211150240
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4X NLGN4Y

6.33e-06288229106499
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4X NLGN4Y

6.33e-06288226456829
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4X NLGN4Y

6.33e-06288224104404
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4X NLGN4Y

6.33e-06288232243781
Pubmed

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis.

VIM ROCK1

6.33e-0628829565595
Pubmed

SYNCRIP-dependent Nox2 mRNA destabilization impairs ROS formation in M2-polarized macrophages.

NOS2 SYNCRIP

6.33e-06288224844655
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4X NLGN4Y

6.33e-06288222989184
Pubmed

Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.

MYH1 MYH4

6.33e-06288211744674
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIDINS220 NLGN4X SYNE1 MACF1 BIRC6

6.66e-0610388510574462
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SESTD1 NLGN4X MAP1A NLGN4Y SYNE1 SPTBN2 MACF1

7.58e-0628188728706196
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNHD1 VIM DST SYNE1 SCN1A RNF213

8.38e-0618788626460568
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

EPS15 DST PDE4DIP ROCK1 GOLGA5

9.59e-0611188522558309
Pubmed

Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.

VIM MYH1 MYH4

1.24e-051888325753484
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST CENPF SYNE1 PDE4DIP MACF1

1.40e-0512088531413325
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

KIDINS220 NLGN4X DOCK9 SPTBN2 ROCK1 APOB SLC39A14 GOLGA5 SLC30A1

1.43e-0556988930639242
Pubmed

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.

MYH1 MYH4 MYH8 HDAC4

1.46e-055888421884692
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

VIM MYH1 MYH4 MYH8 DST MYH13 CENPF HSPA4L SYNE1 SPTBN2 ANKRD30B MACF1 APOB SYNCRIP

1.52e-051442881435575683
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CEP350 KIDINS220 DST MAP1A MACF1 GOLGA3

1.58e-0520988636779422
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CWF19L2 RPGRIP1L MAP1A IFT74 DIAPH1 KIF14 MACF1 ROCK1 CGNL1

1.85e-0558888938580884
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH4

1.90e-05388226059207
Pubmed

Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.

MYH1 MYH4

1.90e-05388236515178
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

1.90e-05388212399109
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN4X NLGN4Y

1.90e-05388232011705
Pubmed

mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety.

DIAPH1 ROCK1

1.90e-05388227880913
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN4X NLGN4Y

1.90e-05388218628683
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4X NLGN4Y

1.90e-05388221282647
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PLEKHB2 CEP350 VIM SESTD1 DST DSCAM IFT74 SYNE1 SPTBN2 PDE4DIP CEP57L1 MACF1 GOLGA3

2.06e-051285881335914814
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DST HDAC4 VWA8 SPTBN2 MACF1

2.06e-0513088512421765
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

VIM RPGRIP1L DST VWA8 CENPF HSPA4L SYNE1 RNF213 SLC39A14 GOLGA5 ECSIT BIRC6 GOLGA3 SYNCRIP

2.28e-051496881432877691
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH4 MYH8

2.33e-052288324301466
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DST MYH13 SYNE1 PDE4DIP GOLGA5 SLC30A1

2.90e-0523388637704626
Pubmed

A human MAP kinase interactome.

CEP350 DST HDAC4 MAP1A SYNE1 SPTBN2 MACF1 CGNL1

3.32e-0548688820936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP350 SPTBN2 RNF213 MACF1 ZNF407 CGNL1 BIRC6 PDZRN4

3.67e-0549388815368895
Pubmed

Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice.

VIM ROCK1

3.79e-05488212177195
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN4X NLGN4Y

3.79e-05488212669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN4X NLGN4Y

3.79e-05488222671294
Pubmed

The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis.

DIAPH1 ROCK1

3.79e-05488219265163
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN4X NLGN4Y

3.79e-05488220579107
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH1 MYH8

3.79e-05488220357587
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH4

3.79e-05488211023856
Pubmed

Raf-1/CK2 and RhoA/ROCK signaling promote TNF-α-mediated endothelial apoptosis via regulating vimentin cytoskeleton.

VIM ROCK1

3.79e-05488228743511
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1

3.79e-0548828954775
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN4X NLGN4Y

3.79e-05488216077734
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH4

3.79e-05488211029314
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN4X NLGN4Y

3.79e-05488217292328
Pubmed

Mouse centromere protein F (Cenpf) gene maps to the distal region of chromosome 1 by interspecific backcross analysis.

CENPF SLC30A1

3.79e-0548829858811
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH4

3.79e-05488218417546
Pubmed

Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.

MYH1 MYH4

3.79e-05488212547197
Pubmed

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.

NLGN4X DSCAM NLGN4Y

3.90e-052688334848499
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

CEP350 MAP1A RNF213 MACF1

4.27e-057688427542412
Pubmed

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.

SESTD1 PDE4DIP MACF1

4.38e-052788318685082
Pubmed

Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy.

VIM MYH4 MYH8

4.90e-052888325179606
Pubmed

Integrating genetic and network analysis to characterize genes related to mouse weight.

CYP2C9 KIDINS220 VWA8

5.45e-052988316934000
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

VIM MYH1 MYH4 MYH8 DST SYNE1 KIF14 RNF213 MACF1 SYNCRIP

5.50e-05844881025963833
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

VIM SNPH KIDINS220 DST MAP1A HSPA4L SYNE1 SPTBN2 PDE4DIP MACF1 CGNL1 GOLGA3 SYNCRIP

6.23e-051431881337142655
Pubmed

Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.

MYH1 MYH4

6.30e-05588230737693
Pubmed

Differential expression of N-CAM, vimentin and MAP1B during initial pathfinding of olfactory receptor neurons in the mouse embryo.

VIM MAP1A

6.30e-0558828651505
Pubmed

Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition.

DIAPH1 ROCK1

6.30e-05588215096506
Pubmed

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion.

DIAPH1 ROCK1

6.30e-05588219160018
Pubmed

Gastrointestinal factors influencing zinc absorption and homeostasis.

SLC39A14 SLC30A1

6.30e-05588221462106
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NLGN4X NLGN4Y

6.30e-05588218923512
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN4X NLGN4Y

6.30e-05588210996085
InteractionSYCE1 interactions

EVI5 STX19 EPS15 CENPF IFT74 ROCK1 CCDC136 GOLGA3

7.67e-08127878int:SYCE1
InteractionCEP63 interactions

CEP350 CWF19L2 DST DSCAM IFT74 SYNE1 CEP57L1 KIF14 MACF1

7.96e-08179879int:CEP63
InteractionGOLGA1 interactions

CEP350 DST IFT74 CEP57L1 MACF1 GOLGA5 BIRC6 GOLGA3

1.26e-06183878int:GOLGA1
InteractionDISC1 interactions

CEP350 CWF19L2 DST MAP1A IFT74 SYNE1 PDE4DIP CEP57L1 MACF1 CCDC136 SYNCRIP

2.34e-064298711int:DISC1
InteractionABTB2 interactions

MYH1 MYH4 MYH8 IFT74 KIF14 BIRC6

4.96e-06101876int:ABTB2
InteractionRAB35 interactions

KIDINS220 DST DOCK9 SPTBN2 DIAPH1 KIF14 MACF1 ROCK1 SLC39A14 GOLGA5 SLC30A1 GOLGA3

6.33e-065738712int:RAB35
InteractionAPC interactions

RPGRIP1L DST HDAC4 SYNE1 SPTBN2 DIAPH1 KIF14 MACF1 CGNL1 NOS2

6.82e-063898710int:APC
InteractionMAPRE3 interactions

CEP350 DST MAP1A CENPF IFT74 PDE4DIP KIF14 MACF1

6.86e-06230878int:MAPRE3
InteractionOCLN interactions

EPS15 KIDINS220 DST FATE1 SPTBN2 KIF14 MACF1 SLC39A14 GOLGA5 SLC30A1 GOLGA3

1.00e-055008711int:OCLN
InteractionSYNC interactions

VIM EPS15 GOLGA5 CCDC136 GOLGA3

1.04e-0567875int:SYNC
InteractionRSPH6A interactions

MYH1 MYH4 MYH8 MYH13

1.36e-0534874int:RSPH6A
InteractionCDC5L interactions

VIM CWF19L2 EPS8L2 DST HDAC4 SYNE1 PDE4DIP WRN DIAPH1 MED12L KIF14 MACF1 CCDC136 SYNCRIP

1.67e-058558714int:CDC5L
InteractionPHF21A interactions

EPS15 DST MYH13 CENPF IFT74 KIF14 GOLGA5 BIRC6 GOLGA3

1.72e-05343879int:PHF21A
InteractionKRT8 interactions

CEP350 VIM MYH1 RPGRIP1L HSPA4L IFT74 KIF14 BIRC6 NOS2 GOLGA3

2.02e-054418710int:KRT8
InteractionRHOQ interactions

KIDINS220 DST DOCK9 SPTBN2 KIF14 ROCK1 SLC39A14 GOLGA5 SLC30A1 GOLGA3

2.06e-054428710int:RHOQ
InteractionEZR interactions

KIDINS220 DST MYH13 HDAC4 HSPA4L IFT74 KIF14 MACF1 ROCK1 SLC39A14 GOLGA3

2.56e-055538711int:EZR
InteractionMYBPC2 interactions

AMPD1 MYH8 DST PDE4DIP

4.22e-0545874int:MYBPC2
InteractionKALRN interactions

SESTD1 HDAC4 DSCAM SPTBN2 MACF1

5.99e-0596875int:KALRN
InteractionNDC80 interactions

CEP350 RPGRIP1L IFT74 KIF14 ROCK1 BIRC6 CCDC136 GOLGA3

6.10e-05312878int:NDC80
InteractionPFN1 interactions

CEP350 EPS15 KIDINS220 MAP1A IFT74 DIAPH1 KIF14 MACF1 BIRC6 GOLGA3

6.78e-055098710int:PFN1
InteractionBFSP1 interactions

VIM DSCAM BIRC6 GOLGA3

7.49e-0552874int:BFSP1
InteractionMYH8 interactions

MYH4 MYH8 MYH13 SUGP1

7.49e-0552874int:MYH8
InteractionKRT18 interactions

CEP350 VIM RPGRIP1L CCDC42 IFT74 PDE4DIP KIF14 BIRC6 NOS2

8.16e-05419879int:KRT18
InteractionPCNT interactions

CEP350 RPGRIP1L DST SYNE1 SPTBN2 KIF14 MACF1

8.31e-05241877int:PCNT
InteractionDSCAM interactions

VIM DST DSCAM SYNE1 PDE4DIP MACF1

9.78e-05171876int:DSCAM
InteractionSAR1B interactions

GSTM5 KIDINS220 MYH13 PTS SMC6 TMED2 GOLGA5 GOLGA3

1.09e-04339878int:SAR1B
InteractionSYNGR1 interactions

PLEKHB2 FATE1 APOB GOLGA5 ECSIT

1.10e-04109875int:SYNGR1
InteractionCDH1 interactions

EPS15 EPS8L2 KIDINS220 DST DOCK9 SPTBN2 DIAPH1 MACF1 ROCK1 GOLGA5 SLC30A1 GOLGA3

1.11e-047688712int:CDH1
InteractionTERF2 interactions

DST CENPF HSPA4L PTS SYNE1 SMC6 WRN MACF1

1.11e-04340878int:TERF2
InteractionLZTR1 interactions

MYH1 MYH4 MYH8 MYH13 HDAC4

1.19e-04111875int:LZTR1
InteractionRHOG interactions

KIDINS220 VWA8 DOCK9 SPTBN2 DIAPH1 KIF14 MACF1 ROCK1 SLC39A14 GOLGA5 ECSIT SLC30A1 IPO11

1.38e-049108713int:RHOG
InteractionDIRAS3 interactions

KIDINS220 DST SPTBN2 MACF1 SLC39A14 SLC30A1 GOLGA3

1.40e-04262877int:DIRAS3
InteractionERGIC1 interactions

SPTBN2 KIF14 TMED2 SLC39A14 GOLGA5 SLC30A1 BIRC6

1.46e-04264877int:ERGIC1
InteractionP2RY12 interactions

APOB GOLGA5 ECSIT IPO11

1.49e-0462874int:P2RY12
InteractionLCK interactions

KIDINS220 DST PTS SPTBN2 KIF14 MACF1 GOLGA5 NOS2 GOLGA3

1.73e-04463879int:LCK
InteractionNEFM interactions

EVI5 VIM DSCAM VWA8 SYNE1 KIF14

1.74e-04190876int:NEFM
InteractionTSPAN33 interactions

MYH1 MYH4 MYH8 MYH13

1.79e-0465874int:TSPAN33
InteractionGRIPAP1 interactions

CWF19L2 HDAC4 HSPA4L CEP57L1 CGNL1 GOLGA5

1.84e-04192876int:GRIPAP1
InteractionKDM1A interactions

CEP350 VIM STX19 EPS15 RPGRIP1L DST CENPF IFT74 PDE4DIP KIF14 GOLGA5 BIRC6 GOLGA3

1.91e-049418713int:KDM1A
InteractionSYT3 interactions

MYH4 HDAC4 SYNCRIP

2.11e-0427873int:SYT3
InteractionPRKAG2 interactions

MYH1 MYH4 MYH8 MAP1A

2.14e-0468874int:PRKAG2
InteractionRDX interactions

DST HDAC4 CENPF KIF14 MACF1 ROCK1 SLC39A14

2.29e-04284877int:RDX
InteractionIQGAP1 interactions

VIM MYH1 EPS15 DST HDAC4 DSCAM SPTBN2 DIAPH1 KIF14 SYNCRIP

2.29e-045918710int:IQGAP1
InteractionASAH2 interactions

MYH1 MYH4

2.73e-046872int:ASAH2
InteractionCEP128 interactions

CEP350 VIM RPGRIP1L IFT74 KIF14 TMED2 IPO11

3.00e-04297877int:CEP128
InteractionYIPF2 interactions

VIM FATE1 APOB

3.20e-0431873int:YIPF2
InteractionRAC3 interactions

KIDINS220 DOCK9 SPTBN2 DIAPH1 KIF14 MACF1 ROCK1 SLC39A14 GOLGA5 SLC30A1

3.32e-046198710int:RAC3
InteractionKCNA3 interactions

DNHD1 VIM EPS15 KIDINS220 DST HSPA4L ABCA13 RNF213 MACF1 ROCK1 SLC30A1 SYNCRIP

3.54e-048718712int:KCNA3
InteractionLZTS2 interactions

VIM SESTD1 CWF19L2 RPGRIP1L CEP57L1 KIF14 CGNL1 SLC39A14 BIRC6

3.64e-04512879int:LZTS2
InteractionTRIM37 interactions

CEP350 VIM CWF19L2 MYH4 RPGRIP1L MYH13 MAP1A DSCAM KIF14 SYNCRIP

3.81e-046308710int:TRIM37
InteractionMEGF10 interactions

VIM HDAC4 VWA8

3.86e-0433873int:MEGF10
InteractionC11orf52 interactions

KIDINS220 DST DOCK9 SPTBN2 MACF1 SLC39A14 SLC30A1

3.96e-04311877int:C11orf52
InteractionATOH1 interactions

CEP350 MAP1A RNF213 MACF1

3.99e-0480874int:ATOH1
InteractionCIT interactions

VIM DSCAM CCDC42 VWA8 CENPF SYNE1 SPTBN2 KIF14 RNF213 MACF1 PCDHA6 TMED2 APOB CFAP43 BIRC6 SYNCRIP

4.29e-0414508716int:CIT
InteractionELAVL3 interactions

HDAC4 HSPA4L ECSIT

4.60e-0435873int:ELAVL3
Cytoband17p13.1

MYH1 MYH4 MYH8 CCDC42

8.19e-0511888417p13.1
Cytoband12q12

ADAMTS20 PUS7L PDZRN4

1.04e-044788312q12
CytobandEnsembl 112 genes in cytogenetic band chr12q12

ADAMTS20 PUS7L PDZRN4

2.49e-0463883chr12q12
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MYH1 MYH4 MYH8 MYH13 CCDC42

5.55e-04346885chr17p13
Cytoband14q32.12

GOLGA5 UNC79

1.43e-032988214q32.12
GeneFamilyMyosin heavy chains

MYH1 MYH4 MYH8 MYH13 MYH16

6.96e-10155651098
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

2.61e-048562939
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHB2 DOK6 DOCK9 SPTBN2 ROCK1

4.36e-04206565682
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

CEP350 RPGRIP1L WRN MED12L KIF14 MACF1 VWA3B BIRC6

1.70e-07180888M8239
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

DOK6 NLGN4X DSCAM PDE4DIP MED12L ROCK1 UNC79 CCDC136 ADCY8 PDZRN4

7.72e-065068810M39067
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CEP350 CWF19L2 KIDINS220 HSPA4L IFT74 SMC6 WRN KIF14 ZNF407 JAKMIP2 PUS7L

1.24e-056568811M18979
CoexpressionLAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR

VIM DST RBMS3 SYNE1 DOCK9 MACF1

1.26e-05152886M39243
CoexpressionHUMMERICH_SKIN_CANCER_PROGRESSION_DN

MYH1 MYH4 MYH8 DST ECSIT

2.57e-05103885M1170
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CEP350 EVI5 EPS15 KIDINS220 DST HDAC4 CENPF DOCK9 WRN KIF14 MACF1 ROCK1

2.87e-058568812M4500
CoexpressionHUMMERICH_SKIN_CANCER_PROGRESSION_DN

MYH1 MYH4 MYH8 DST ECSIT

3.68e-05111885MM1111
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH4 MYH8

4.00e-0520883M1123
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH4 MYH8

4.66e-0521883MM1102
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

SESTD1 MYH4 NLGN4X MYH13 RBMS3 SCARA5 PDZRN4

7.32e-081818872b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

DOK6 DST NLGN4Y RNF213 ZNF407 SLC39A14

1.37e-061768863de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

DOK6 DST NLGN4Y RNF213 ZNF407 SLC39A14

1.41e-0617788682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH4 MYH8 NLGN4X MYH13 RBMS3 SCARA5

1.83e-061858868f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

KIDINS220 KIF14 RNF213 MACF1 SLC30A1 BIRC6

1.83e-06185886a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

KIDINS220 KIF14 RNF213 MACF1 SLC30A1 BIRC6

1.88e-061868868571956890fc9894d766ba294a28e376b4aba428
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOK6 MYH1 MYH4 MYH13 SCN1A UNC79

1.88e-06186886bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

RPGRIP1L HSPA4L IFT74 SYNE1 ERICH2 CFAP43

2.00e-061888868f30535a32968a81a304315a49c0d90a77d36948
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPGRIP1L HSPA4L IFT74 PRR29 ERICH2 CFAP43

2.07e-06189886fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPGRIP1L HSPA4L IFT74 PRR29 ERICH2 CFAP43

2.07e-06189886565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPGRIP1L HSPA4L IFT74 PRR29 ERICH2 CFAP43

2.07e-06189886497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

VIM SESTD1 NLGN4X RBMS3 SCARA5 PDZRN4

2.40e-06194886014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

NLGN4X MAP1A VWA3B APOB CCDC168

4.42e-061228852aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 MYH13

6.99e-0662884a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 MYH13

6.99e-0662884ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 ABCA13 CFAP43 ADCY8

7.78e-061378850aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13 RBMS3

1.51e-05157885741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 WDR87 PRR29 VWA3B CFAP43

1.86e-051648850e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 MYH8 ABCA13 ADCY8

1.86e-05164885382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

MYH4 NLGN4X MYH13 RBMS3 SCARA5

2.15e-051698856373562ab3b1765060212a6a53d6543e7e942e80
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13 RBMS3

2.21e-051708858ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SYNE1 RNF213 MACF1 ZNF407 APOB

2.27e-051718852e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH4 MYH8 NLGN4X MYH13 RBMS3

3.06e-05182885fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 ADAMTS20 APOB UNC79

3.22e-051848852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 ADAMTS20 APOB UNC79

3.22e-05184885ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 ADAMTS20 APOB UNC79

3.22e-051848852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM RBMS3 SYNE1 DOCK9 CGNL1

3.31e-05185885fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CYP2C9 SYNE1 RNF213 MACF1 JAKMIP2

3.31e-05185885097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellE15.5-Epithelial-airway_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STX19 HSPA4L DIAPH1 ROCK1 CGNL1

3.40e-05186885bb2c7af3b1d8478c49a8626dbfd6c92c5e7adc4a
ToppCellE15.5-Epithelial-airway_epithelial_cell-club_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STX19 HSPA4L DIAPH1 ROCK1 CGNL1

3.40e-0518688586c809b99088d3d6c8f87785797c4beefdcddbe7
ToppCellPND28-Epithelial-Epithelial_Airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPA4L IFT74 PRR29 ERICH2 CFAP43

3.48e-05187885f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM RBMS3 SYNE1 DOCK9 CGNL1

3.48e-0518788537d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM RBMS3 SYNE1 DOCK9 CGNL1

3.48e-05187885ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

MAP1A PRR29 VWA3B ERICH2 CFAP43

3.57e-051888856833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH4 NLGN4X MYH13 RBMS3 SCARA5

3.57e-05188885fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellMulticiliated|World / shred by cell class for nasal brushing

MAP1A PRR29 VWA3B ERICH2 CFAP43

3.66e-0518988534b110aef839376228c5a403a6b5047a945f472b
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A SYNE1 VWA3B ERICH2 CFAP43

3.76e-051908859ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A SYNE1 VWA3B ERICH2 CFAP43

3.76e-05190885833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIDINS220 DST ABCA13 CGNL1 PDZRN4

3.85e-05191885297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIDINS220 DST ABCA13 CGNL1 PDZRN4

3.85e-05191885e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A SYNE1 PRR29 VWA3B CFAP43

3.95e-05192885be592e661367affced9ebe80849b466e6adb3a34
ToppCellCiliated-cil-3|World / Class top

RPGRIP1L SYNE1 PRR29 ERICH2 CFAP43

3.95e-051928854989ebb8812b8af1870599acd932849122c05a29
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIM NLGN4X RBMS3 JAKMIP2 PDZRN4

4.05e-05193885549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.05e-051938850b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SCN1A PRR29 VWA3B CFAP43

4.05e-05193885bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SESTD1 NLGN4X RBMS3 SCARA5 PDZRN4

4.15e-0519488511c79a8c56ece42713b04b321982e41e239f07a5
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

PLEKHB2 EPS8L2 RBMS3 PDE4DIP PDZRN4

4.15e-05194885b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

PLEKHB2 EPS8L2 RBMS3 PDE4DIP PDZRN4

4.15e-0519488581e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

VIM SESTD1 NLGN4X MYH13 SCARA5

4.15e-05194885d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RPGRIP1L ABCA13 SYNE1 PRR29 CFAP43

4.15e-051948854a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

VIM SESTD1 NLGN4X RBMS3 SCARA5

4.25e-05195885f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

SYNE1 DIAPH1 RNF213 MACF1 JAKMIP2

4.25e-05195885ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.25e-051958853486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 DIAPH1 RNF213 MACF1 JAKMIP2

4.36e-05196885af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SESTD1 EPS8L2 DST RBMS3 CGNL1

4.36e-051968856731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST HSPA4L MACF1 CGNL1 PDZRN4

4.36e-05196885c936014125b2ed5f796221b74acb77b8f8359875
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SESTD1 EPS8L2 DST RBMS3 CGNL1

4.36e-051968856856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.36e-05196885d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOK6 DST RBMS3 SCARA5 MACF1

4.36e-051968857d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

SESTD1 NLGN4X RBMS3 SCARA5 PDZRN4

4.36e-05196885e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DST RBMS3 SYNE1 MACF1 SLC39A14

4.46e-05197885fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A ABCA13 SYNE1 VWA3B CFAP43

4.46e-0519788591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A ABCA13 SYNE1 VWA3B CFAP43

4.46e-0519788522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RPGRIP1L SYNE1 PRR29 VWA3B CFAP43

4.46e-0519788574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A ABCA13 SYNE1 VWA3B CFAP43

4.46e-051978853bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A ABCA13 SYNE1 VWA3B CFAP43

4.46e-0519788587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAP1A RBMS3 SCARA5 SMC6 MED12L

4.46e-0519788515230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 DIAPH1 RNF213 MACF1 JAKMIP2

4.46e-05197885d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.57e-05198885ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOK6 DST RBMS3 SCARA5 MACF1

4.57e-051988858f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CWF19L2 SYNE1 RNF213 MACF1 ZNF407

4.68e-05199885f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DSCAM SYNE1 SCN1A DOCK9 UNC79

4.68e-0519988519a97e27a4758e794ce7246d295e112b47931a48
ToppCell(10)_Ciliated|World / shred by cell type by condition

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.79e-052008851b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIDINS220 DST DOCK9 RNF213 MACF1

4.79e-0520088572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DST DOCK9 RNF213 MACF1 BIRC6

4.79e-05200885dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-05200885f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-05200885cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOK6 DST RBMS3 SCARA5 PDZRN4

4.79e-05200885389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIM NLGN4X RBMS3 SYNE1 PDZRN4

4.79e-05200885a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIDINS220 DST DOCK9 RNF213 MACF1

4.79e-052008855c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOK6 VIM SYNE1 MED12L SLC39A14

4.79e-05200885c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-05200885c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

MAP1A SYNE1 PRR29 VWA3B CFAP43

4.79e-052008853305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIDINS220 DST DOCK9 RNF213 MACF1

4.79e-0520088579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CEP350 RNF213 MACF1 ROCK1 BIRC6

4.79e-0520088512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIM RBMS3 SCARA5 SYNE1 PDZRN4

4.79e-05200885c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYNE1 DIAPH1 RNF213 MACF1 JAKMIP2

4.79e-052008852281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-052008854fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-05200885310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

SYNE1 DIAPH1 RNF213 MACF1 JAKMIP2

4.79e-05200885f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

DST RBMS3 PDE4DIP JAKMIP2 PDZRN4

4.79e-05200885c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIM RBMS3 SCARA5 SYNE1 PDZRN4

4.79e-052008850c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOK6 NLGN4X DSCAM SCN1A PDZRN4

4.79e-05200885961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

MYH1 MYH8 SYNE1 MACF1

9.14e-05119884a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE1 RNF213 MACF1 APOB

9.75e-0512188419333a660800b583fa27b495c1f7828e6636a257
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

1.11e-04125884d05556ea185c15815a4f8643f1c01185badbeece
ToppCell-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

GSTM5 AMPD1 SCARA5 PDZRN4

1.21e-04128884dab10774bc0532a1664fd8ac2b54cffab01be55a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 ABCA13 ADCY8

1.53e-0413688482b1d6d839c0d0c68e0960549f688138479defcc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

1.90e-0414488471107275767a0728541a3695715c44874b3e5efc
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 SCARA5 APOB ADCY8

1.96e-04145884f142b86d4da5b71c189da46cbc4beebdc387ffee
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CEP350 SYNE1 MACF1 ROCK1

6.40e-0549484GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST SYNE1 RNF213 MACF1

6.93e-0550484GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.27e-0810844DOID:0080326 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

2.97e-0812844DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

2.97e-0812844DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

4.28e-0813844DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

8.14e-0815844DOID:0050646 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13 CENPF

3.37e-0680845DOID:12930 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

1.08e-0548844DOID:423 (implicated_via_orthology)
DiseaseColorectal Carcinoma

AMPD1 NLGN4X ABCA13 SYNE1 SPTBN2 WRN APOB JAKMIP2 ADCY8 PDZRN4

3.09e-057028410C0009402
Diseasearthrogryposis multiplex congenita (is_implicated_in)

MYH8 SYNE1

4.79e-054842DOID:0080954 (is_implicated_in)
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYH13

5.13e-0571844DOID:0050700 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

GSTM5 NLGN4X DSCAM NLGN4Y SCN1A

7.55e-05152845DOID:0060041 (implicated_via_orthology)
Diseasecerebellar ataxia (is_implicated_in)

RPGRIP1L SYNE1

7.96e-055842DOID:0050753 (is_implicated_in)
DiseaseSilicosis

NOS2 PDZRN4

2.85e-049842C0037116
Diseaseprotein CREG1 measurement

SUGP1 GOLGA5

2.85e-049842EFO_0801937
DiseaseIntellectual Disability

HDAC4 PTS SYNE1 SCN1A DIAPH1 MED12L MACF1

2.90e-04447847C3714756
Diseasemigraine disorder

SESTD1 CENPF SUGP1 RNF213 MACF1 PDZRN4

5.53e-04357846MONDO_0005277
DiseaseManganese Poisoning

SLC39A14 NOS2

7.13e-0414842C0677050
Diseasebipolar disorder, response to lithium ion

SESTD1 PTS

7.13e-0414842GO_0010226, MONDO_0004985
Diseaseserum IgG glycosylation measurement

CWF19L2 DSCAM IFT74 WRN ZNF407 GOLGA5 ADCY8

7.37e-04523847EFO_0005193
Diseaselow density lipoprotein triglyceride measurement

SUGP1 APOB

8.21e-0415842EFO_0009946
Diseaseamenorrhea, response to antineoplastic agent

APOB ADCY8

8.21e-0415842EFO_0010269, GO_0097327
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

MYH13 HDAC4 RNF213

1.11e-0371843EFO_0004735, EFO_0007965
Diseasenevus count

HDAC4 SLC30A1

1.19e-0318842EFO_0004632
DiseaseMeckel syndrome type 1

RPGRIP1L KIF14

1.19e-0318842C3714506
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

SUGP1 APOB

1.19e-0318842EFO_0008317, EFO_0008589
Diseasemetabolonic lactone sulfate measurement

CYP2C9 MYH16

1.33e-0319842EFO_0800659
Diseaseempathy measurement

RBMS3 ADAMTS20 UNC79 GOLGA3

1.43e-03170844EFO_0009183
Diseaseanti-Mullerian hormone measurement

MYH4 MCM8

1.47e-0320842EFO_0004769
Diseasesystemising measurement

FATE1 DSCAM

1.62e-0321842EFO_0010221
DiseaseRetinal Diseases

VIM NOS2

2.68e-0327842C0035309

Protein segments in the cluster

PeptideGeneStartEntry
EINEMKELREHNENM

ADCY8

936

P40145
EMLLMEKTQNHEQDG

ERICH2

111

A1L162
ILNMMEENDKLENIA

CFAP43

821

Q8NDM7
PEMKMQRHLNEKNEE

ANKRD30B

1336

Q9BXX2
DQHLAMMVALQEDIQ

BIRC6

1911

Q9NR09
KEIQDLAEEIHGMMD

ABCA13

116

Q86UQ4
FQVHQMLNEMDELKE

AMPD1

271

P23109
GLNMEILEEQMLHEI

DNHD1

3751

Q96M86
MRHDLMQSAQEGQEK

CCDC42

181

Q96M95
FEQMLLDMNLNEEKQ

DIAPH1

96

O60610
MNEDLNVMKERVLGH

ADAMTS20

221

P59510
KNMDGMLVVEAVHNL

MROH7

1051

Q68CQ1
LNLEMLEEEHNEAMQ

PDZRN4

506

Q6ZMN7
MDEQELENMLKPFGH

RBMS3

151

Q6XE24
IMMGKAENQDLNEDH

PCDHA6

781

Q9UN73
QEEMLEMAQKGVLHA

NOS2

1026

P35228
ELQKAGIMFQMDNHL

KIF14

786

Q15058
NIDELKKEMNMNFGD

KIDINS220

1251

Q9ULH0
EGAEAALHQKMMELE

JAKMIP2

671

Q96AA8
QEMLAMKHQQELLEH

HDAC4

116

P56524
NLGKEEMGHLMQAED

MAP1A

1231

P78559
QDDIKARQMMHEALQ

MED12L

1506

Q86YW9
DKMGNQHQALLEAME

MCM8

521

Q9UJA3
LMANGDELNMQLKEQ

RPGRIP1L

306

Q68CZ1
RVDILENQVMDNHME

GSTM5

96

P46439
QKEMDQHFGMVELLN

DST

5001

Q03001
EMQREEIQKLMGQIH

GOLGA5

476

Q8TBA6
MGQIHQLRSELQDME

GOLGA5

486

Q8TBA6
NEMAHKFNQEMDQLL

IPO11

811

Q9UI26
KAMEEMNGKDLEGEN

SYNCRIP

386

O60506
MEGDLNEMEIQLNHA

MYH8

1621

P13535
MGNMELAEQLKVQLE

CWF19L2

506

Q2TBE0
ELMQLDMEGMLQHFQ

EVI5

366

O60447
KMEGDLNEMEIQLNH

MYH1

1621

P12882
EILDGMDQSHRKEMQ

CYHR1

201

Q6ZMK1
KQEMDSLQRQMEEHA

GOLGA3

1436

Q08378
GNKDELMQHMDEVND

EPS8L2

581

Q9H6S3
NEGLMDEKLLHNVLM

MACF1

2356

Q9UPN3
QQIEMEKLNHQGELM

MACF1

6166

Q9UPN3
NEEIMSLQMKQLEHD

NLGN4Y

726

Q8NFZ3
TKDDKHEQDMVNGIM

APOB

741

P04114
RQLDMDLEEHQGEMN

IFT74

341

Q96LB3
MKEHENDPEMLVDLQ

DOCK9

1586

Q9BZ29
GEIEENLMKAEQMHQ

CENPF

861

P49454
AEQHERLMLEMEQKA

DOK6

231

Q6PKX4
KLQRELEEQMDMNEH

CGNL1

1231

Q0VF96
LEEQMDMNEHLQGQL

CGNL1

1236

Q0VF96
EEMLKERQSDQDMNH

CEP350

2326

Q5VT06
QSHGLEGLNKEIMME

ASNSD1

511

Q9NWL6
QDELDQMSMEHQELL

CEP57L1

331

Q8IYX8
LMEMKDLENHNSQLN

EPS15

496

P42566
AMNMNVQHEREDKNI

CCDC168

1976

Q8NDH2
EKVKEHQESMDMNNP

CYP2C9

246

P11712
GENQEHLVIAEMMEL

FATE1

26

Q969F0
HVGMELQLKQELAML

SCARA5

266

Q6ZMJ2
EGVMEKLQNGDLDHM

SLC39A14

271

Q15043
NEEIMSLQMKQLEHD

NLGN4X

726

Q8N0W4
EQMENHGVMPNKETE

ECSIT

166

Q9BQ95
NHENLIMDHMVKSDG

DSCAM

366

O60469
QNIEDKVHMPMDCIN

PLEKHB2

41

Q96CS7
QQLAHHKAMMEEIAG

SYNE1

3961

Q8NF91
AEHQALMDEILMLQD

SYNE1

6001

Q8NF91
HTDQIGLALLKNEMM

PUS7L

441

Q9H0K6
KMEGDLNEMEIQLNH

MYH4

1621

Q9Y623
MEMLKHLSPNDNEND

WRN

446

Q14191
LHSMEVAQNGMAKED

SNPH

181

O15079
DNEMNNLQIAVDRMH

SCN1A

1006

P35498
NKENVDHIQGVMEDM

SESTD1

461

Q86VW0
DHIQGVMEDMQLRKQ

SESTD1

466

Q86VW0
QQLRDAEEQMHGMKN

CCDC136

301

Q96JN2
GKMNMNILHQEELIA

SUGP1

26

Q8IWZ8
NIPLVMNNERHKGEM

RNF213

3676

Q63HN8
EQELHMMGQEKAKDE

SPTBN2

1606

O15020
MDKMQVDQEEGHQKC

HSPA4L

526

O95757
EMSEEDVNDMLHQGK

STX19

176

Q8N4C7
QDEIQNMKEEMARHL

VIM

366

P08670
KMEGDLNEMEIQLGH

MYH13

1621

Q9UKX3
EEHMEQQKENMEHLK

SMC6

756

Q96SB8
DLNMEQGMAEHLKDV

TMEM208

91

Q9BTX3
METDLNEMEIQLDHA

MYH16

781

Q9H6N6
EEQLHNEMQLKDEME

ROCK1

436

Q13464
METEAHQNKLEEMIN

TMED2

121

Q15363
DLLELMMLQNAQMHQ

PRR29

46

P0C7W0
DENQTHEMIMERLAG

ZNF713

121

Q8N859
AQIIMQEAQGEHMDL

ZNF407

2121

Q9C0G0
VKEMEQGHSDLEKMQ

VWA3B

681

Q502W6
DHMELEEDRAGQLNM

SLC30A1

231

Q9Y6M5
DNIQHVIVMEDMLKD

VWA8

756

A3KMH1
RHQMKGEDAQPQEMA

ZNF275

51

Q9NSD4
EMQQQMIGEEPLDHL

WDR87

1001

Q6ZQQ6
EEAIMQPLDHKNLDM

PTS

81

Q03393
EQQVDMHDMLLEELA

ZNF449

116

Q6P9G9
QMELQDDGITMGLEH

UNC79

811

Q9P2D8
GQNDTMAKLREMLHQ

PDE4DIP

306

Q5VU43