Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	O-palmitoyltransferase activity	LRAT CPT1A CPT1B	2.80e-06	5	132	3	GO:0016416
GeneOntologyMolecularFunction	carnitine O-palmitoyltransferase activity	CPT1A CPT1B	2.58e-04	4	132	2	GO:0004095
GeneOntologyMolecularFunction	oleoyl-CoA ligase activity	ACSL1 SLC27A4	2.58e-04	4	132	2	GO:0090434
GeneOntologyBiologicalProcess	fatty acid transmembrane transport	CPT1A CPT1B ACSL1 ABCD2	1.04e-05	22	131	4	GO:1902001
GeneOntologyBiologicalProcess	detection of stimulus	SOX2 OR5W2 OR2W5P OR5M3 GRIN2D OR6M1 GRK1 OR51A7 MMP24 PKD2L2 OR51I1 OR51B6 OR4A15 SCARB1 OR52E8 OR1E3	1.41e-05	722	131	16	GO:0051606
GeneOntologyBiologicalProcess	response to oxygen-glucose deprivation	SOX2 INHBA ZEB2	3.98e-05	11	131	3	GO:0090649
GeneOntologyBiologicalProcess	regulation of myofibroblast cell apoptotic process	SOX2 ZEB2	4.00e-05	2	131	2	GO:1904520
GeneOntologyBiologicalProcess	myofibroblast cell apoptotic process	SOX2 ZEB2	4.00e-05	2	131	2	GO:1904516
GeneOntologyBiologicalProcess	sensory perception	SOX2 OR5W2 LRAT MYO7B OR2W5P OR5M3 GRIN2D USH1C OR6M1 GRK1 BSND OR51A7 MMP24 OR51I1 OR51B6 OR4A15 OR52E8 OR1E3 SLITRK6	4.74e-05	1072	131	19	GO:0007600
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	SOX2 OR5W2 OR2W5P OR5M3 GRIN2D OR6M1 OR51A7 MMP24 OR51I1 OR51B6 OR4A15 OR52E8 OR1E3	8.72e-05	582	131	13	GO:0050906
GeneOntologyBiologicalProcess	long-chain fatty acid transport	CPT1A CPT1B ACSL1 ABCD2 SLC27A4	1.09e-04	74	131	5	GO:0015909
GeneOntologyCellularComponent	cyclin-dependent protein kinase activating kinase holoenzyme complex	CCNH CDK7	1.18e-04	3	132	2	GO:0019907
GeneOntologyCellularComponent	transcription factor TFIIK complex	CCNH CDK7	1.18e-04	3	132	2	GO:0070985
GeneOntologyCellularComponent	CAK-ERCC2 complex	CCNH CDK7	2.35e-04	4	132	2	GO:0070516
GeneOntologyCellularComponent	brush border	MYO1E MYO7B MYO18A USH1C ACE2 SLC27A4	4.13e-04	152	132	6	GO:0005903
Domain	SOXp	SOX1 SOX2 SOX3	3.04e-06	5	127	3	PF12336
Domain	SOX_fam	SOX1 SOX2 SOX3	3.04e-06	5	127	3	IPR022097
Domain	Pumilio_RNA-bd	PUM2 PUM1	4.59e-05	2	127	2	IPR033712
Domain	PUF	PUM2 PUM1	1.37e-04	3	127	2	PF00806
Domain	PUM_HD	PUM2 PUM1	1.37e-04	3	127	2	PS50303
Domain	PUM-HD	PUM2 PUM1	1.37e-04	3	127	2	IPR033133
Domain	CPT_N	CPT1A CPT1B	1.37e-04	3	127	2	IPR032476
Domain	CPT_N	CPT1A CPT1B	1.37e-04	3	127	2	PF16484
Domain	PUM	PUM2 PUM1	2.73e-04	4	127	2	PS50302
Domain	Pumilio_RNA-bd_rpt	PUM2 PUM1	2.73e-04	4	127	2	IPR001313
Domain	Pumilio	PUM2 PUM1	2.73e-04	4	127	2	SM00025
Domain	HEAT	TNPO2 BTAF1 PPP2R1B GCN1	3.15e-04	48	127	4	PF02985
Domain	PKNOX/Meis_N	MEIS1 MEIS2	4.53e-04	5	127	2	IPR032453
Domain	Meis_PKNOX_N	MEIS1 MEIS2	4.53e-04	5	127	2	PF16493
Domain	ARM-like	RANGAP1 TNPO2 PUM2 BTAF1 PPP2R1B CEP70 PUM1 GCN1	5.23e-04	270	127	8	IPR011989
Domain	HEAT	TNPO2 BTAF1 PPP2R1B GCN1	6.51e-04	58	127	4	IPR000357
Domain	Carn_acyl_trans	CPT1A CPT1B	9.42e-04	7	127	2	IPR000542
Domain	Carn_acyltransf	CPT1A CPT1B	9.42e-04	7	127	2	PF00755
Domain	ACYLTRANSF_C_1	CPT1A CPT1B	9.42e-04	7	127	2	PS00439
Domain	ACYLTRANSF_C_2	CPT1A CPT1B	9.42e-04	7	127	2	PS00440
Pathway	REACTOME_FORMATION_OF_THE_POSTERIOR_NEURAL_PLATE	SOX1 SOX2 ZEB2	4.51e-05	10	104	3	M48036
Pathway	REACTOME_FORMATION_OF_THE_ANTERIOR_NEURAL_PLATE	SOX1 SOX2 ZEB2	6.17e-05	11	104	3	M48031
Pathway	KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS	CPT1A CPT1B ACSL1	6.17e-05	11	104	3	M47626
Pathway	WP_FATTY_ACID_BETAOXIDATION	GCDH CPT1A CPT1B ACSL1	1.09e-04	34	104	4	M39596
Pathway	WP_FATTY_ACID_BETAOXIDATION	GCDH CPT1A CPT1B ACSL1	1.09e-04	34	104	4	MM15937
Pubmed	Distinct SoxB1 networks are required for naïve and primed pluripotency.	SOX1 SOX2 SOX3	5.34e-08	3	132	3	29256862
Pubmed	Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages.	SOX1 SOX2 SOX3	2.13e-07	4	132	3	10446282
Pubmed	A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.	SOX1 SOX2 SOX3	5.31e-07	5	132	3	2374589
Pubmed	Dental Epithelial Stem Cells Express the Developmental Regulator Meis1.	SOX2 MEIS1 MEIS2	5.31e-07	5	132	3	30914971
Pubmed	Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4DCAF5 ubiquitin ligase.	SOX1 SOX2 SOX3 GPS1	7.35e-07	19	132	4	30442713
Pubmed	A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis.	CREBBP MEIS1 MEIS2	1.06e-06	6	132	3	15161102
Pubmed	Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells.	SOX1 SOX2 SOX3	1.85e-06	7	132	3	15456859
Pubmed	Pairing SOX off: with partners in the regulation of embryonic development.	SOX1 SOX2 SOX3	1.85e-06	7	132	3	10729834
Pubmed	Evidence that the SRY protein is encoded by a single exon on the human Y chromosome.	SOX1 SOX2 SOX3	1.85e-06	7	132	3	8244390
Pubmed	Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.	SOX2 MEIS1 MEIS2	1.85e-06	7	132	3	20413611
Pubmed	A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.	SOX2 SOX3 MEIS1 MEIS2	2.36e-06	25	132	4	19369396
Pubmed	Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.	SOX1 SOX2 SOX3 ZEB2	2.78e-06	26	132	4	22992956
Pubmed	Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source.	SOX1 SOX2 SOX3	2.95e-06	8	132	3	23776550
Pubmed	Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and Testes.	SOX1 SOX2 SOX3	2.95e-06	8	132	3	28515211
Pubmed	Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.	SOX2 SOX3 ZEB2	4.41e-06	9	132	3	12522767
Pubmed	Sox2 induces neuronal formation in the developing mammalian cochlea.	SOX1 SOX2 SOX3	4.41e-06	9	132	3	20071536
Pubmed	Sox2 requirement in sonic hedgehog-associated medulloblastoma.	SOX1 SOX2 SOX3	4.41e-06	9	132	3	23596255
Pubmed	Identification of transcripts with enriched expression in the developing and adult pancreas.	KCNE3 RGS11 AKR1C4 GRIK5 IDE USH1C ONECUT1 MEIS1 ACSL1 ACE2 NOP58 CCDC198	4.95e-06	624	132	12	18554416
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	SOX2 INHBA ZEB2 MEIS2 ZNF250 PTPRD CELSR2 SLITRK6	5.61e-06	251	132	8	29031500
Pubmed	Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.	SOX1 SOX2 SOX3	6.29e-06	10	132	3	32150534
Pubmed	From head to toes: the multiple facets of Sox proteins.	SOX1 SOX2 SOX3	6.29e-06	10	132	3	10037800
Pubmed	Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.	SOX1 SOX2 SOX3	1.15e-05	12	132	3	27246266
Pubmed	Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1.	SOX1 SOX2 SOX3	1.15e-05	12	132	3	15882093
Pubmed	Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.	SOX1 SOX2 SOX3	1.15e-05	12	132	3	11071752
Pubmed	Variants within the muscle and liver isoforms of the carnitine palmitoyltransferase I (CPT1) gene interact with fat intake to modulate indices of obesity in French-Canadians.	CPT1A CPT1B	1.43e-05	2	132	2	17089095
Pubmed	A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase.	CCNH CDK7	1.43e-05	2	132	2	8069918
Pubmed	Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency.	CCNH CDK7	1.43e-05	2	132	2	37591314
Pubmed	Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.	PUM2 PUM1	1.43e-05	2	132	2	12459267
Pubmed	Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.	PUM2 PUM1	1.43e-05	2	132	2	29165587
Pubmed	HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry.	ACE2 SCARB1	1.43e-05	2	132	2	33244168
Pubmed	Transcription Factors Sox2 and Sox3 Directly Regulate the Expression of Genes Involved in the Onset of Oligodendrocyte Differentiation.	SOX2 SOX3	1.43e-05	2	132	2	38891067
Pubmed	PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.	PUM2 PUM1	1.43e-05	2	132	2	35507203
Pubmed	Bespoke RNA recognition by Pumilios.	PUM2 PUM1	1.43e-05	2	132	2	26517885
Pubmed	Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.	MYO7B USH1C	1.43e-05	2	132	2	28439001
Pubmed	Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.	PUM2 PUM1	1.43e-05	2	132	2	12667987
Pubmed	A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins.	PUM2 PUM1	1.43e-05	2	132	2	31078383
Pubmed	SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/β-catenin pathway.	SOX1 SOX2	1.43e-05	2	132	2	26040764
Pubmed	Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.	PUM2 PUM1	1.43e-05	2	132	2	32753408
Pubmed	A cyclin associated with the CDK-activating kinase MO15.	CCNH CDK7	1.43e-05	2	132	2	8078587
Pubmed	Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.	PUM2 PUM1	1.43e-05	2	132	2	32437472
Pubmed	High Membranous Expression of Fatty Acid Transport Protein 4 Is Associated with Tumorigenesis and Tumor Progression in Clear Cell Renal Cell Carcinoma.	ACSL1 SLC27A4	1.43e-05	2	132	2	31089396
Pubmed	Expression in Escherichia coli: purification and characterization of cyclin H, a subunit of the human general transcription/DNA repair factor TFIIH.	CCNH CDK7	1.43e-05	2	132	2	9056480
Pubmed	MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease.	MEIS1 MEIS2	1.43e-05	2	132	2	29716922
Pubmed	Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B).	CPT1A CPT1B	1.43e-05	2	132	2	9070950
Pubmed	Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model.	PUM2 PUM1	1.43e-05	2	132	2	32316190
Pubmed	[Expression and clinical significance of cyclin H and CDK7 in human hemangiomas].	CCNH CDK7	1.43e-05	2	132	2	18950027
Pubmed	Low expression of cyclinH and cyclin-dependent kinase 7 can decrease the proliferation of human esophageal squamous cell carcinoma.	CCNH CDK7	1.43e-05	2	132	2	23456497
Pubmed	Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation.	MEIS1 MEIS2	1.43e-05	2	132	2	18408019
Pubmed	Meiotic expression of the cyclin H/Cdk7 complex in male germ cells of the mouse.	CCNH CDK7	1.43e-05	2	132	2	11319144
Pubmed	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors.	MEIS1 MEIS2	1.43e-05	2	132	2	34035267
Pubmed	Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.	PUM2 PUM1	1.43e-05	2	132	2	12771951
Pubmed	Alternate modes of cognate RNA recognition by human PUMILIO proteins.	PUM2 PUM1	1.43e-05	2	132	2	21397187
Pubmed	Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator.	ONECUT1 CREBBP	1.43e-05	2	132	2	15304484
Pubmed	Do SOD2 and SOD3 gene polymorphisms impact the oral health-related quality of life in Para athletes?	SOX2 SOX3	1.43e-05	2	132	2	39109770
Pubmed	Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex.	MYO7B USH1C	1.43e-05	2	132	2	26812017
Pubmed	Expression and regulation of carnitine palmitoyltransferase-Ialpha and -Ibeta genes.	CPT1A CPT1B	1.43e-05	2	132	2	10408760
Pubmed	Novel blood biomarkers of pancreatic cancer-associated diabetes mellitus identified by peripheral blood-based gene expression profiles.	VNN1 MMP9	1.43e-05	2	132	2	20571492
Pubmed	Cloning, expression and subcellular localization of the human homolog of p40MO15 catalytic subunit of cdk-activating kinase.	CCNH CDK7	1.43e-05	2	132	2	7936635
Pubmed	PUMILIO proteins promote colorectal cancer growth via suppressing p21.	PUM2 PUM1	1.43e-05	2	132	2	35338151
Pubmed	Homeodomain proteins: an update.	ONECUT1 MEIS2	1.43e-05	2	132	2	26464018
Pubmed	Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.	PUM2 PUM1	1.43e-05	2	132	2	18776931
Pubmed	Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis.	CPT1A CPT1B	1.43e-05	2	132	2	9013572
Pubmed	Seven new members of the Sox gene family expressed during mouse development.	SOX1 SOX2 SOX3	1.49e-05	13	132	3	8441686
Pubmed	The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.	SOX2 MEIS1 MEIS2	1.49e-05	13	132	3	27918583
Pubmed	A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.	SOX1 SOX2 SOX3	1.49e-05	13	132	3	8625802
Pubmed	Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.	SOX1 SOX2 SOX3	1.49e-05	13	132	3	12194848
Pubmed	Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.	CPT1B CCNH PPARGC1B CDK7	1.80e-05	41	132	4	17276355
Pubmed	Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro.	SOX1 SOX2 SOX3	1.89e-05	14	132	3	21766338
Pubmed	Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart.	CPT1A CPT1B SLC27A4	1.89e-05	14	132	3	18502258
Pubmed	Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.	SOX1 SOX2 SOX3	2.35e-05	15	132	3	15893981
Pubmed	Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells.	SOX1 SOX2 SOX3	2.35e-05	15	132	3	21331042
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	LRRC8C RANGAP1 TNPO2 IQSEC2 GRIK5 GAL3ST2 CPT1B ITGAE ARHGEF17 TRMT6 KARS1 CCDC198	2.55e-05	736	132	12	29676528
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	MYO1E MYO7B MYO18A USH1C	2.62e-05	45	132	4	22114352
Pubmed	Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes.	SOX1 SOX2 SOX3	2.89e-05	16	132	3	24257626
Pubmed	Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages.	SOX1 SOX2 SOX3	2.89e-05	16	132	3	17699610
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANGAP1 EXOSC10 PNKP MYO1E POLD1 TNPO2 ELP1 GCDH BTAF1 DENND1A PPP2R1B NOP58 KARS1 GUSB SLC25A28 GCN1 SLC27A4	3.36e-05	1440	132	17	30833792
Pubmed	Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh.	SOX1 SOX2 SOX3	3.50e-05	17	132	3	23444355
Pubmed	TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration.	SOX1 SOX2 SOX3	3.50e-05	17	132	3	35950911
Pubmed	Spatio-temporal expression of Sox genes in murine palatogenesis.	SOX1 SOX2 SOX3	3.50e-05	17	132	3	27241892
Pubmed	AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.	CPT1A CPT1B ACSL1	4.18e-05	18	132	3	16054041
Pubmed	Expression of Sox genes in tooth development.	SOX1 SOX2 SOX3	4.18e-05	18	132	3	26864488
Pubmed	Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction.	SOX1 SOX2	4.28e-05	3	132	2	9609835
Pubmed	Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells.	CCNH CDK7	4.28e-05	3	132	2	15695176
Pubmed	Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer.	CCNH CDK7	4.28e-05	3	132	2	27301701
Pubmed	Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs.	PUM2 PUM1	4.28e-05	3	132	2	30333515
Pubmed	Conserved regulation of proximodistal limb axis development by Meis1/Hth.	MEIS1 MEIS2	4.28e-05	3	132	2	10586884
Pubmed	Genomic structure of and a cardiac promoter for the mouse carnitine palmitoyltransferase II gene.	CPT1A CPT1B	4.28e-05	3	132	2	8307575
Pubmed	A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.	PUM2 PUM1	4.28e-05	3	132	2	25340845
Pubmed	HIV-1 Tat interacts with LIS1 protein.	CCNH CDK7	4.28e-05	3	132	2	15698475
Pubmed	Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.	PUM2 PUM1	4.28e-05	3	132	2	26724866
Pubmed	Polymorphisms of CAK genes and risk for lung cancer: a case-control study in Chinese population.	CCNH CDK7	4.28e-05	3	132	2	17707548
Pubmed	Interaction with CCNH/CDK7 facilitates CtBP2 promoting esophageal squamous cell carcinoma (ESCC) metastasis via upregulating epithelial-mesenchymal transition (EMT) progression.	CCNH CDK7	4.28e-05	3	132	2	25820824
Pubmed	Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex.	SOX1 SOX2	4.28e-05	3	132	2	19061938
Pubmed	Cyclic AMP responsive element-binding protein induces metastatic renal cell carcinoma by mediating the expression of matrix metallopeptidase-2/9 and proteins associated with epithelial-mesenchymal transition.	CREBBP MMP9	4.28e-05	3	132	2	28487942
Pubmed	Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF).	ONECUT1 CREBBP	4.28e-05	3	132	2	10811635
Pubmed	The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H.	CCNH CDK7	4.28e-05	3	132	2	12140753
Pubmed	Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina.	SOX1 SOX2	4.28e-05	3	132	2	27031842
Pubmed	Genetics of septo-optic dysplasia.	SOX2 SOX3	4.28e-05	3	132	2	17587179
Pubmed	Cell cycle-dependent stimulation of the HIV-1 promoter by Tat-associated CAK activator.	CCNH CDK7	4.28e-05	3	132	2	10639311
Pubmed	Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development.	MEIS1 MEIS2	4.28e-05	3	132	2	18216174
Cytoband	9q33.3	RABEPK NR6A1 DENND1A	1.68e-04	37	132	3	9q33.3
GeneFamily	SRY-boxes	SOX1 SOX2 SOX3	1.24e-04	19	94	3	757
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	GLDN MYO1E DENND1A ZEB2 PPARGC1B TTC7B GFOD1	1.34e-06	192	127	7	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLDN INHBA TM6SF1 DENND1A ZEB2 PPARGC1B TTC7B	1.64e-06	198	127	7	e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLDN INHBA TM6SF1 DENND1A ZEB2 PPARGC1B TTC7B	1.64e-06	198	127	7	0baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E RBMS1 ARHGEF17 ZEB2 MEIS1	6.44e-06	159	127	6	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E RBMS1 ARHGEF17 ZEB2 MEIS1	9.44e-06	170	127	6	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E RBMS1 ARHGEF17 ZEB2 MEIS1	9.44e-06	170	127	6	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRAT MYO18A CPT1A CCDC198 PTPRD SLC27A4	1.04e-05	173	127	6	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRAT MYO18A CPT1A CCDC198 PTPRD SLC27A4	1.04e-05	173	127	6	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC80 ARHGEF17 ZEB2 MEIS1 PDE8B ZFTA	1.15e-05	176	127	6	e9152defb4fd41267fb33c42c01fd0c683280783
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC80 ARHGEF17 ZEB2 MEIS1 PDE8B ZFTA	1.15e-05	176	127	6	a4d269075aa0efc46fa251b379f334e50c69391d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC80 ARHGEF17 ZEB2 MEIS1 PDE8B ZFTA	1.15e-05	176	127	6	cc6f65a7d2c622841c9d1ab3755586039d4ccc4d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 INHBA ACSL1 MMP9 ABCD2 SLC27A4	1.19e-05	177	127	6	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 INHBA ACSL1 MMP9 ABCD2 SLC27A4	1.19e-05	177	127	6	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RBMS1 CCDC80 ARHGEF17 ZEB2 MEIS1 PDE8B	1.35e-05	181	127	6	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RBMS1 CCDC80 ARHGEF17 ZEB2 MEIS1 PDE8B	1.35e-05	181	127	6	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SOX2 SPEF2 CCDC80 APOBEC4 LMO1 SLITRK6	1.39e-05	182	127	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CCDC80 ZEB2 MEIS1 PTPRD RAI14 SLITRK6	1.53e-05	185	127	6	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CCDC80 ZEB2 MEIS1 PTPRD RAI14 SLITRK6	1.53e-05	185	127	6	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SOX1 SOX2 SOX3 KCNH7 RGS11 USH1C	1.57e-05	186	127	6	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	RAPSN ZEB2 PTPRD RAI14 SLITRK6 MMP9	1.72e-05	189	127	6	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	INHBA TLCD4 ARHGEF17 EDEM3 VNN1 MMP9	1.77e-05	190	127	6	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TM6SF1 DENND1A ZEB2 PPARGC1B TTC7B VNN1	2.24e-05	198	127	6	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	Parenchymal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLDN INHBA DENND1A ZEB2 PPARGC1B TTC7B	2.30e-05	199	127	6	7ee2805fd9143eba11bf6832267b62189683608b
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TM6SF1 DENND1A ZEB2 ACSL1 PPARGC1B VNN1	2.37e-05	200	127	6	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX2 RABEPK RAPSN LMO1 PDE8B SLITRK6	2.37e-05	200	127	6	de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCell	Bronchial-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLDN INHBA DENND1A ZEB2 ACSL1 PPARGC1B	2.37e-05	200	127	6	2f5b71e55c2de0e77fdae6667eb57f333acc6cd1
Drug	clomoxir	CPT1A CPT1B ABCD2 SLC27A4	9.72e-07	14	130	4	CID000054221
Drug	POCA	CPT1A CPT1B ABCD2 SLC27A4	1.38e-05	26	130	4	CID000054217
Drug	NS3763	GRIK5 GRM5 KARS1	1.49e-05	9	130	3	CID004359312
Drug	N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A	SUPT3H MYO1E IQSEC2 NR6A1 PPP2R1B PTPRD BTBD7 RAI14	1.67e-05	195	130	8	2626_UP
Drug	troglitazone; Up 200; 10uM; HL60; HT_HG-U133A	STARD8 IQSEC2 ELP1 CPT1A MLH3 CELSR2 SCARB1 FCMR	1.80e-05	197	130	8	1173_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; PC3; HT_HG-U133A	TNPO2 ELP1 CPT1A CPT1B FCF1 PKD2L2 PDE8B FCMR	1.86e-05	198	130	8	6725_DN
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A	SOX2 STARD8 IQSEC2 ELP1 GRIK5 MEIS1 ZNF250 FCMR	2.00e-05	200	130	8	6766_UP
Drug	LY293558	GRIK5 GRIN2D GRM5 KARS1	2.48e-05	30	130	4	CID000127894
Drug	GYKI 53655	GRIK5 GRIN2D GRM5 KARS1	2.48e-05	30	130	4	CID000126757
Drug	4-methylglutamic acid	GRIK5 GRIN2D GRM5 KARS1	2.83e-05	31	130	4	CID000005365
Drug	eliprodil	GRIK5 GRIN2D GRM5 GUSB	2.83e-05	31	130	4	CID000060703
Drug	Bt-m	SOX2 CPT1A ABCD2 SLC27A4	3.65e-05	33	130	4	CID000005963
Drug	osthol	CPT1A ACSL1 MMP9	3.85e-05	12	130	3	ctd:C046627
Drug	5,6,7-trimethoxyflavone	CPT1A ABCD2 SLC27A4	3.85e-05	12	130	3	CID000442583
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	RAPSN CPT1A BSND CELSR2 OR4A15 SCARB1 TGDS RBM6 MMP9	5.70e-06	303	124	9	EFO_0004612, EFO_0020945
Disease	congestive heart failure (implicated_via_orthology)	SOX2 GRK1 ACE2 MMP9	2.67e-05	41	124	4	DOID:6000 (implicated_via_orthology)
Disease	phosphatidylcholine 36:6 measurement	RAPSN MAU2	5.24e-05	3	124	2	EFO_0021474
Disease	free cholesterol to total lipids in small HDL percentage	RAPSN CPT1A CELSR2 TGDS	6.37e-05	51	124	4	EFO_0022285
Disease	free cholesterol to total lipids in large HDL percentage	RAPSN CELSR2 SCARB1 MMP9	9.21e-05	56	124	4	EFO_0022279
Disease	intracranial aneurysm (implicated_via_orthology)	ARHGEF17 MMP9	1.05e-04	4	124	2	DOID:10941 (implicated_via_orthology)
Disease	free cholesterol in very large HDL measurement	RAPSN CELSR2 SCARB1 MMP9	1.37e-04	62	124	4	EFO_0022273
Disease	omega-3 polyunsaturated fatty acid measurement	RAPSN AKR1C4 MAU2 CPT1A CELSR2	1.45e-04	118	124	5	EFO_0010119
Disease	Restless Legs Syndrome	MEIS1 PTPRD	1.74e-04	5	124	2	C0035258
Disease	phosphatidylcholine (16:0/22:5n3, 18:1/20:4) measurement	RAPSN CPT1A	1.74e-04	5	124	2	EFO_0800467
Disease	omega-6 polyunsaturated fatty acid measurement	RAPSN OR2W5P AKR1C4 BSND CELSR2 SCARB1	1.91e-04	197	124	6	EFO_0005680
Disease	docosahexaenoic acid measurement	RAPSN NUF2 MAU2 CPT1A CELSR2	2.04e-04	127	124	5	EFO_0007761
Disease	apolipoprotein A 1 measurement	RAPSN AKNA PUM2 AKR1C4 CPT1A GRM5 MEIS1 PPARGC1B CELSR2 SCARB1 TGDS RBM6	2.47e-04	848	124	12	EFO_0004614
Disease	hair colour measurement	SUPT3H INHBA PUM2 NR6A1 GRM5 DENND1A SCARB1 TGDS EFCAB8 RAI14	2.80e-04	615	124	10	EFO_0007822
Disease	phospholipid measurement	KCNH7 RAPSN TLCD4 AKR1C4 SCARB1	3.20e-04	140	124	5	EFO_0004639
Disease	alkaline phosphatase measurement	SUPT3H RAPSN AKR1C4 GRIK5 CPT1A ONECUT1 EDEM3 NOP58 GUSB TGDS RAI14 MMP9 MLST8	3.54e-04	1015	124	13	EFO_0004533
Disease	Septo-Optic Dysplasia	SOX2 SOX3	3.63e-04	7	124	2	C0338503
Disease	Tourette syndrome, bipolar disorder	TLCD4 MAU2	3.63e-04	7	124	2	EFO_0004895, MONDO_0004985
Disease	Mammary Carcinoma, Human	STARD8 ELP1 CPT1A ZEB2 MEIS1 CCNH PPARGC1B PTPRD MMP9	3.88e-04	525	124	9	C4704874
Disease	Mammary Neoplasms, Human	STARD8 ELP1 CPT1A ZEB2 MEIS1 CCNH PPARGC1B PTPRD MMP9	3.88e-04	525	124	9	C1257931
Disease	Mammary Neoplasms	STARD8 ELP1 CPT1A ZEB2 MEIS1 CCNH PPARGC1B PTPRD MMP9	3.99e-04	527	124	9	C1458155
Disease	Breast Carcinoma	STARD8 ELP1 CPT1A ZEB2 MEIS1 CCNH PPARGC1B PTPRD MMP9	4.63e-04	538	124	9	C0678222
Disease	triacylglycerol 56:8 measurement	RAPSN MAU2 CPT1A	4.67e-04	36	124	3	EFO_0010435
Disease	restless legs syndrome (implicated_via_orthology)	MEIS1 MEIS2	4.82e-04	8	124	2	DOID:0050425 (implicated_via_orthology)
Disease	asthma, type 2 diabetes mellitus	RAPSN IDE	4.82e-04	8	124	2	MONDO_0004979, MONDO_0005148
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	RAPSN MAU2 CPT1A CELSR2	4.83e-04	86	124	4	EFO_0008595, EFO_0020945
Disease	tongue squamous cell carcinoma (is_marker_for)	SOX2 FANCM MMP9	5.07e-04	37	124	3	DOID:0050865 (is_marker_for)
Disease	free cholesterol to total lipids in large VLDL percentage	RAPSN CELSR2 SCARB1	5.07e-04	37	124	3	EFO_0022281
Disease	fatty acid measurement	RAPSN AKR1C4 GRIK5 MAU2 CPT1A PTPRD CELSR2 SCARB1	5.28e-04	436	124	8	EFO_0005110
Disease	renal cell carcinoma	MYO7B ZEB2 SCARB1	7.38e-04	42	124	3	EFO_0000681
Disease	Aortic Aneurysm, Abdominal	ACE2 MMP9	7.71e-04	10	124	2	C0162871
Disease	level of Sterol ester (27:1/18:3) in blood serum	RAPSN MAU2	7.71e-04	10	124	2	OBA_2045193
Disease	phosphatidylcholine 32:0 measurement	RAPSN PTPRD	9.40e-04	11	124	2	EFO_0010372
Disease	level of Sterol ester (27:1/20:5) in blood serum	RAPSN CPT1A	9.40e-04	11	124	2	OBA_2045197
Disease	suntan	GRM5 MMP24 PPARGC1B TGDS	9.53e-04	103	124	4	EFO_0004279
Disease	arachidonoylcarnitine (C20:4) measurement	RAPSN CPT1A	1.12e-03	12	124	2	EFO_0800544
Disease	lymphangioleiomyomatosis (is_marker_for)	CPT1A MMP9	1.12e-03	12	124	2	DOID:3319 (is_marker_for)
Disease	rheumatic heart disease (biomarker_via_orthology)	INHBA ZEB2	1.12e-03	12	124	2	DOID:0050827 (biomarker_via_orthology)
Disease	Streptozotocin Diabetes	CPT1A CPT1B ACSL1 MMP9	1.14e-03	108	124	4	C0038433
Disease	Diabetes Mellitus, Experimental	CPT1A CPT1B ACSL1 MMP9	1.14e-03	108	124	4	C0011853
Disease	Alloxan Diabetes	CPT1A CPT1B ACSL1 MMP9	1.14e-03	108	124	4	C0002152
Disease	restless legs syndrome	MEIS1 PTPRD LMO1	1.16e-03	49	124	3	EFO_0004270
Disease	pathological myopia	OR5M3 DENND1A ZEB2 PTPRD	1.26e-03	111	124	4	EFO_0004207
Disease	phosphatidylcholine measurement	RAPSN TLCD4 AKR1C4 GRIK5 VNN1 SCARB1	1.30e-03	284	124	6	EFO_0010226
Disease	dihomo-linolenoylcarnitine (C20:3n3 or 6) measurement	RAPSN CPT1A	1.33e-03	13	124	2	EFO_0800547
Disease	free cholesterol to total lipids in small LDL percentage	RAPSN CELSR2 TGDS	1.46e-03	53	124	3	EFO_0022286
Disease	Diabetic Neuralgia	GRM5 MMP9	1.54e-03	14	124	2	C0751074
Disease	Diabetic Neuropathies	GRM5 MMP9	1.54e-03	14	124	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	GRM5 MMP9	1.54e-03	14	124	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	GRM5 MMP9	1.54e-03	14	124	2	C0271673
Disease	Diabetic Mononeuropathy	GRM5 MMP9	1.54e-03	14	124	2	C0271678
Disease	Diabetic Autonomic Neuropathy	GRM5 MMP9	1.54e-03	14	124	2	C0271686
Disease	Diabetic Amyotrophy	GRM5 MMP9	1.54e-03	14	124	2	C0271685
Disease	Diabetic Polyneuropathies	GRM5 MMP9	1.54e-03	14	124	2	C0271680
Disease	level of Phosphatidylethanolamine (18:1_18:1) in blood serum	RAPSN MYO1E	1.54e-03	14	124	2	OBA_2045142
Disease	Diabetic Asymmetric Polyneuropathy	GRM5 MMP9	1.54e-03	14	124	2	C0393835
Disease	cholesterol to total lipids in large HDL percentage	RAPSN CELSR2 SCARB1	1.62e-03	55	124	3	EFO_0022234
Disease	phospholipids in medium HDL measurement	RAPSN CELSR2 SCARB1	1.62e-03	55	124	3	EFO_0022295
Disease	phosphatidylcholine 36:3 measurement	RAPSN KIF2B	1.77e-03	15	124	2	EFO_0010381
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	RAPSN SCARB1	1.77e-03	15	124	2	OBA_2045131
Disease	total lipids in medium HDL measurement	RAPSN CELSR2 SCARB1	1.89e-03	58	124	3	EFO_0022310
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	RAPSN BSND CELSR2 SCARB1 TGDS MMP9	1.93e-03	307	124	6	EFO_0004612, EFO_0020946
Disease	cholesteryl esters to total lipids in large HDL percentage	RAPSN CELSR2 SCARB1	1.98e-03	59	124	3	EFO_0022248
Disease	level of triacylglycerol (56:6) in blood serum	RAPSN MAU2	2.02e-03	16	124	2	OBA_2020007
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	RAPSN TLCD4	2.02e-03	16	124	2	OBA_2045093
Disease	free cholesterol to total lipids in medium HDL percentage	RAPSN CELSR2 SCARB1	2.08e-03	60	124	3	EFO_0022282
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	RAPSN AKR1C4 CELSR2 OR4A15 SCARB1 MMP9	2.20e-03	315	124	6	EFO_0004612, EFO_0008591
Disease	eicosapentaenoate EPA; 20:5n3 measurement	RAPSN GRIK5	2.29e-03	17	124	2	EFO_0021049
Disease	hypertrophic cardiomyopathy (is_marker_for)	ACE2 MMP9	2.29e-03	17	124	2	DOID:11984 (is_marker_for)
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	RAPSN AKR1C4 CELSR2 OR4A15 SCARB1 MMP9	2.41e-03	321	124	6	EFO_0004612, EFO_0004639
Disease	level of Phosphatidylcholine (16:0_22:5) in blood serum	RAPSN CPT1A	2.56e-03	18	124	2	OBA_2045079
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	RAPSN CPT1A BSND CELSR2	2.71e-03	137	124	4	EFO_0004611, EFO_0008591
Disease	total lipids in very large HDL measurement	RAPSN CELSR2 SCARB1	2.73e-03	66	124	3	EFO_0022312
Disease	lipid measurement, high density lipoprotein cholesterol measurement	RAPSN AKR1C4 CELSR2 OR4A15 SCARB1 MMP9	2.77e-03	330	124	6	EFO_0004529, EFO_0004612
Disease	testosterone measurement	SOX1 STARD8 INHBA IQSEC2 AKNA AKR1C4 NUF2 MAU2 ONECUT1 PDE8B SCARB1 TGDS CEP70	2.78e-03	1275	124	13	EFO_0004908
Disease	sensorineural hearing loss (implicated_via_orthology)	SCARB1 SLITRK6	2.86e-03	19	124	2	DOID:10003 (implicated_via_orthology)
Disease	level of Phosphatidylethanolamine (18:0_20:4) in blood serum	RAPSN MYO1E	2.86e-03	19	124	2	OBA_2045140
Disease	squamous cell carcinoma (is_marker_for)	SOX2 MMP9	2.86e-03	19	124	2	DOID:1749 (is_marker_for)
Disease	sodium-coupled monocarboxylate transporter 1 measurement	RAPSN CELSR2	2.86e-03	19	124	2	EFO_0802076
Disease	leukemia (implicated_via_orthology)	MEIS1 MEIS2	2.86e-03	19	124	2	DOID:1240 (implicated_via_orthology)
Disease	cholesterol in very large HDL measurement	RAPSN CELSR2 SCARB1	3.10e-03	69	124	3	EFO_0022229
Disease	temporal lobe epilepsy (is_marker_for)	GRIK5 MMP9	3.17e-03	20	124	2	DOID:3328 (is_marker_for)
Disease	selenium measurement, response to dietary selenium supplementation	EFNA2 LMO1	3.17e-03	20	124	2	EFO_0006331, EFO_0600021
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	RAPSN CPT1A BSND CELSR2 SCARB1	3.45e-03	239	124	5	EFO_0008317, EFO_0020945
Disease	gestational age, birth measurement	RAPSN PTPRD	3.49e-03	21	124	2	EFO_0005112, EFO_0006921
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	RAPSN CPT1A CELSR2 SCARB1 TGDS	3.70e-03	243	124	5	EFO_0004612, EFO_0020944
Disease	Attention Deficit Disorder	GRM5 PTPRD	3.83e-03	22	124	2	C0041671
Disease	Minimal Brain Dysfunction	GRM5 PTPRD	3.83e-03	22	124	2	C1321905
Disease	proprotein convertase subtilisin/kexin type 9 measurement	RAPSN BSND	3.83e-03	22	124	2	EFO_0009312
Disease	phosphatidylserines measurement	RAPSN GRIK5	4.18e-03	23	124	2	EFO_0020049

Protein segments in the cluster

Peptide	Gene	Start	Entry
LYDVLRMYHQTMDVA	USH1C	26	Q9Y6N9
MANDPNYLHRMTTLF	PPP2R1B	501	P30154
RNYRYVVMDFLMDHP	AKR1C4	301	P17516
SMAAMVSFPPQRYHY	ERI3	131	O43414
EEGMMINISIGYHYP	ERVK-18	36	O42043
YLNNSVMEYHPRIIM	CCNH	91	P51946
LMDYHRNMGYLNSSP	CFAP97	461	Q9P2B7
NIPRTMLMYDIVHYS	CXorf58	211	Q96LI9
QHMFYIPQRPYMSLG	ABCD2	541	Q9UBJ2
MQAHELFRYFRMPEL	ACSL1	1	P33121
YIHPESMLFEMNGYL	APOBEC4	91	Q8WW27
MQRAYAALGLPYMNQ	CREBBP	481	Q92793
GPLMVNSNYYAMDLL	CPT1A	246	P50416
VLAMLAYNMRDQHLY	GLDN	516	Q6ZMI3
VRDVNTGPMRFYYML	CELSR2	2471	Q9HCU4
LTPNQMHVMMYGVYR	C1GALT1C1	281	Q96EU7
MLNHLYFYIMPVFNV	CPA6	226	Q8N4T0
APHASEGYYRLMMSL	CCDC80	156	Q76M96
LRPMSMLYYDDGQNI	INHBA	396	P08476
YGPLMALNHMVQQDY	RANGAP1	536	P46060
YRMHLLYAVQGQMDE	RAI14	946	Q9P0K7
AMSQYHMAVAYRLLG	RAPSN	206	Q13702
AMQGAYLPQYAHMQT	RBMS1	361	P29558
MTPAGALDTMYQYHT	RABEPK	261	Q7Z6M1
RYVLDDAQLHIYMLM	RGS11	386	O94810
ISNYHCMMALPYITE	INTS9	101	Q9NV88
DGPHSALYTMMKDQY	PUM2	986	Q8TB72
IVLIRMDYQLHTPMY	OR5W2	46	Q8NH69
MAQRYDDLPHYGGMD	MEIS1	1	O00470
PAFEMVMRARDNVYH	LMO1	96	P25800
YVESLRTLMQGYMQP	ARHGEF17	1081	Q96PE2
PSAIMAPFYQYMETH	MMP24	296	Q9Y5R2
HSSVPEALMYPMYRF	MMP9	411	P14780
LYEYLQNRMMAIAPN	NOP58	271	Q9Y2X3
INAIYSMAYGLHNMQ	GRM5	401	P41594
IQRLYSGTARYHMQM	KCNH7	666	Q9NS40
MAQRYDELPHYGGMD	MEIS2	1	O14770
PLVEMHMQLFQNSYY	IQSEC2	1026	Q5JU85
PGRDDNSYMYILFVM	KCNE3	51	Q9Y6H6
NYMEHAYPADELMPL	EDEM3	66	Q9BZQ6
SLYHGYELLQQMGMR	FANCM	366	Q8IYD8
HPYNMIMFNYLDQKL	DDX58	381	O95786
VNIYDSMPLRYSNIM	EXTL2	301	Q9UBQ6
YMTSMALNYPRNLQL	ITGAE	866	P38570
MIAAAGYQHIRMYDL	MLST8	56	Q9BVC4
LYPYRFTKGMIHSMQ	MLH3	1176	Q9UHC1
MAYDRYMAICKPLHE	OR4A15	146	Q8NGL6
HEPMYYFLAMLAVSD	OR51A7	56	Q8NH64
HNLHEPMYYFLAMLA	OR51B6	51	Q9H340
MDVRLHTPMYFFLGN	OR2W5P	51	A6NFC9
ALHQPMYYFLSMLAL	OR51I1	56	Q9H343
VYGIRLEHFYMMPVN	NUF2	56	Q9BZD4
LLDAMRMYRQGYPDH	MYO18A	1101	Q92614
RMYRQGYPDHMVFSE	MYO18A	1106	Q92614
IQYVNPAFERMMGYH	PDE8B	291	O95263
MFVVIYDLRDMPANH	FAM214A	971	Q32MH5
QYFSPYVSADMHRMA	GPS1	376	Q13098
MNNLYTPYHKDVAGM	ONECUT1	161	Q9UBC0
QRMQMYNSPYHRVTD	SLC25A28	196	Q96A46
YGIYLGDNRVAHMMP	LRAT	61	O95237
AYGEHLMQEHMYEPA	ELP1	991	O95163
HVRDGYIMMFNYLPI	GCN1	1751	Q92616
MAFDRYMAIGNPLLY	OR5M3	116	Q8NGP4
YMAICDPLHYTVIMN	OR6M1	121	Q8NGM8
DGPHSALYTMMKDQY	PUM1	1106	Q14671
QPMYYFLGILAMADI	OR56B2P	66	Q8NGI1
MPELQYMARLYALQF	GAL3ST2	371	Q9H3Q3
ESYGYVLPNHMMLKI	EXOSC10	526	Q01780
MSHDRPQVYGTFYAM	BSND	26	Q8WZ55
LYMCLQYPSTAVRHM	BTAF1	1111	O14981
YPRMNEVYTRLGEMN	CEP70	486	Q8NHQ1
MSVQSSLVMHPIYAY	GCDH	141	Q92947
IMYISNHRYNIERMP	FCF1	176	Q9Y324
AYMLMTLQGLEYLHQ	CDK7	116	P50613
FRTSHYPYAEEVMQM	GUSB	381	P08236
SAAMALYNPYRHDMV	COQ4	56	Q9Y3A0
MGHIQYDMAYAAQPF	ACE2	376	Q9BYF1
ELQMEQVYHGLMERY	AKNA	751	Q7Z591
DMPMFSALLHYLYTG	BTBD7	191	Q9P203
EEGMMINISIGYHYP	ERVK-21	146	P61565
DYNMYLVHNGRMLIH	FBXO40	306	Q9UH90
VNNMLHLYASMLYER	DENND1A	181	Q8TEH3
MRKSQYRLHFYLPMT	EFCAB8	126	A8MWE9
PPAERMEHYVLYMVN	EFNA2	81	O43921
EQPHQHAMYYLRLLM	IDE	676	P14735
PHGTSLMNYLRMVEY	GRIK5	341	Q16478
VMTIMNGGDIRYHIY	GRK1	266	Q15835
PMYTSENRQYLHKMQ	CCDC198	141	Q9NVL8
LVYLVTVMHSMQAGY	MAU2	291	Q9Y6X3
LYPSIMMAHNLCYTT	POLD1	606	P28340
MLSAYLRMKYPHLVA	DPP7	166	Q9UHL4
GRSPLMVNSNYYVMD	CPT1B	246	Q92523
RNPNYEIMHMIEEYR	KIF2B	181	Q8N4N8
VMYTGVTHMLNPFIY	OR1E3	276	Q8WZA6
IYGHVTLMRAQRNYM	PTPRD	1581	P23468
LHEPMYYFLAMLDSI	OR52E8	61	Q6IFG1
REQYMGMSVPPHYQY	NR6A1	211	Q15406
TSMDYRGREAPHMNY	RBM6	141	P78332
YRMLTNNLIPYKLMH	SPEF2	446	Q9C093
PMHRYDVSALQYNSM	SOX2	196	P48431
LPPMHRYDMAGLQYS	SOX3	296	P41225
SLYEQHMVSPMVHVY	SLITRK6	676	Q9H5Y7
YHNELDMNLYMRIAP	KARS1	286	Q15046
DMNLYMRIAPELYHK	KARS1	291	Q15046
SAAHYYPKLMSIMGN	GFOD1	106	Q9NXC2
IYTLMHRDSYPRFMN	RGS20	356	O76081
NLPSASMYERSYMHR	PPWD1	76	Q96BP3
RMVDGYMKLYHPNNA	SMYD1	376	Q8NB12
AMVQLIRYMHTYCLP	PPARGC1B	286	Q86YN6
YTQLVLMPKVMHYAQ	SCARB1	431	Q8WTV0
LMPKVMHYAQYVLLA	SCARB1	436	Q8WTV0
EYMYTDLQALHMLPQ	SPATA16	356	Q9BXB7
HIPVSDMVMYGYRKQ	PNKP	471	Q96T60
MHRYDMGALQYSPIS	SOX1	246	O00570
MPGVELYHYVTDSMA	STARD8	901	Q92502
SHMIVSLVEDYPNYM	TGDS	31	O95455
HMMAFQLGPTEASYY	UBFD1	271	O14562
PAQRGLYRNVMMETY	ZNF250	41	P15622
MGMRVNFLASNIHYP	VNN1	256	O95497
QSMMYSLGDARRPLH	SUPT3H	31	O75486
MAALVYYGFRMRPND	SLC27A4	266	Q6P1M0
TLAQAMMYTQHPEQY	TNPO2	616	O14787
YVSLYHQPAAMMEDS	FCMR	366	O60667
IVRIASMLPHYGFMY	TLCD4	186	Q96MV1
TFGMVNPHMYYLNKV	PKD2L2	46	Q9NZM6
MYYAREPGKINHMRY	TRMT6	171	Q9UJA5
EAANLFPMSHNVLYM	TTC7B	721	Q86TV6
FPMSHNVLYMRGQIA	TTC7B	726	Q86TV6
LDQMSFLPHMAYTYP	ZEB2	926	O60315
EMLLHRHYYLQGMID	VRTN	111	Q9H8Y1
VMLENYSHLVSMGYP	ZNF300	36	Q96RE9
LEYLMDFNPARHGMV	ZFTA	111	C9JLR9
HRGIQMYESNGYTMV	WDR54	91	Q9H977
GSAHYLMYLVMVAAI	TM6SF1	116	Q9BZW5
PGDMQIYSMIYDANH	WDR64	411	B1ANS9
IYSMIYDANHGMLIT	WDR64	416	B1ANS9
AFMLHMIDQYDPLYS	LRRC8C	371	Q8TDW0
PHIYALADNMYRNMI	MYO1E	86	Q12965
APEERNYHIFYCMLM	MYO7B	246	Q6PIF6
NIRSNYPDMHSYMVR	GRIN2D	721	O15399
YPDMHSYMVRYNQPR	GRIN2D	726	O15399