Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEGF_extracell

TENM1 ADAM33 LTBP2

2.65e-0460393IPR013111
DomainEGF_2

TENM1 ADAM33 LTBP2

2.65e-0460393PF07974
DomainRRM_1

ELAVL1 A1CF RBM12 EIF4B

9.06e-04208394PF00076
DomainRRM

ELAVL1 A1CF RBM12 EIF4B

1.06e-03217394SM00360
DomainRRM_dom

ELAVL1 A1CF RBM12 EIF4B

1.25e-03227394IPR000504
DomainRRM

ELAVL1 A1CF RBM12 EIF4B

1.31e-03230394PS50102
Domain-

ELAVL1 A1CF RBM12 EIF4B

1.63e-032443943.30.70.330
DomainNucleotide-bd_a/b_plait

ELAVL1 A1CF RBM12 EIF4B

2.00e-03258394IPR012677
Domain-

TPRX1 ZFHX2 SSH2 MYBL1

2.80e-032833941.10.10.60
DomainHomeodomain-like

TPRX1 ZFHX2 SSH2 MYBL1

4.94e-03332394IPR009057
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NEK1 SORBS1 HIVEP1 SSH2 SIK3 DLC1 USO1 EIF4B KIF2C

3.65e-0786139936931259
Pubmed

Human antigen R as a therapeutic target in pathological cardiac hypertrophy.

ELAVL1 A1CF

1.23e-06239230668549
Pubmed

Circular RNA circDLC1 inhibits MMP1-mediated liver cancer progression via interaction with HuR.

ELAVL1 DLC1

3.67e-06339233391541
Pubmed

The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix.

TENM1 SORBS1

3.67e-06339215777793
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ELAVL1 RANBP2 SORBS1 SSH2 IGF2R SIK3 UNC79 KIF2C

9.64e-0696339828671696
Pubmed

Interaction network of human early embryonic transcription factors.

TPRX1 BCL9L RANBP2 HIVEP1 NAB2

4.42e-0535139538297188
Pubmed

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.

NEK1 FEZ2

9.48e-051339214690447
Pubmed

Proteomic analysis reveals that MAEL, a component of nuage, interacts with stress granule proteins in cancer cells.

ELAVL1 EIF4B

1.27e-041539224189637
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RANBP2 IGF2R USO1 HSPA4L EIF4B KIF2C

1.28e-0470839639231216
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

ELAVL1 RBM12 FEZ2 USO1 EIF4B KIF2C

1.44e-0472339634133714
Pubmed

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

ELAVL1 NEK1 A1CF SIK3 EIF4B

1.64e-0446439532457219
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ELAVL1 RANBP2 HIVEP1 RBM12 EIF4B NAB2 KIF2C

2.00e-04110339734189442
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZFHX2 SSH2 DLC1

2.07e-0410239311214970
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RANBP2 SORBS1 ZFAT HIVEP1 EIF4B

2.25e-0449739523414517
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

SORBS1 USO1 HSPA4L EIF4B

5.70e-0434139429791485
Pubmed

Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.

SPTLC3 PELI2

7.12e-043539223192594
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ELAVL1 RANBP2 HIVEP1 IGF2R IDH3G USO1 HSPA4L

9.29e-04142539730948266
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RBM12 MAN1A2 IGF2R SIK3 IDH3G USO1 NAB2

1.03e-03145139730550785
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

RANBP2 USO1 EIF4B

1.07e-0317939336261009
InteractionVCF2 interactions

ELAVL1 HIVEP1

1.09e-053392int:VCF2
GeneFamilyRNA binding motif containing

ELAVL1 A1CF RBM12 EIF4B

1.95e-04213254725
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A1CF DACH2 PHYHIPL UNC79

1.27e-05164394be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTLC3 ANKRD42 DACH2 ANXA13

1.60e-05174394f1510b0f7771936adf29ae3572feab55db31832b
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTLC3 ANKRD42 DACH2 ANXA13

1.60e-051743945d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PELI2 SORBS1 LTBP2 DLC1

1.67e-051763949bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PELI2 SORBS1 LTBP2 DLC1

1.67e-051763943f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS1 LTBP2 DACH2 PHYHIPL

1.71e-05177394b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODXL2 TMEM184A HSPA4L UNC79

1.75e-05178394d3a75a8082e70543b84c35d53fe77625300d19fa
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODXL2 TMEM184A HSPA4L UNC79

1.75e-05178394b2cda1df801b1a1a41e3dd2808baef37765cd804
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TENM1 A1CF HSPA4L PHYHIPL

1.87e-051813946980ea624151da32b7f537f263e40fcb87a02e81
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

A1CF DACH2 PHYHIPL UNC79

1.91e-0518239457bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PODXL2 DACH2 PHYHIPL UNC79

2.08e-051863942fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PODXL2 DACH2 PHYHIPL UNC79

2.08e-05186394ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PODXL2 DACH2 PHYHIPL UNC79

2.08e-05186394714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPTLC3 PODXL2 LTBP2 DACH2

2.12e-05187394387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SPTLC3 PODXL2 LTBP2 DACH2

2.21e-051893940abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SPTLC3 PODXL2 LTBP2 DACH2

2.40e-051933942f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

ADAM33 LTBP2 DLC1 DACH2

2.40e-05193394e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 SPTLC3 PELI2 SSH2

2.50e-05195394938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 SPTLC3 PELI2 SSH2

2.50e-05195394d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

HIVEP1 SIK3 TMEM184A GJB4

2.60e-05197394b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPRX1 PODXL2 DACH2 UNC79

2.65e-051983948f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPRX1 PODXL2 DACH2 UNC79

2.65e-05198394e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM1 ADAM33 LTBP2 DLC1

2.76e-05200394b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM1 ADAM33 LTBP2 DLC1

2.76e-0520039458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellLPS_only-Endothelial-Epi-like|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM33 TMEM184A KIF2C

1.82e-041263934c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCellLPS_only-Endothelial-Epi-like-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM33 TMEM184A KIF2C

1.82e-04126393e065304f480a5e38532b66508b0ee87cc48bba9b
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PODXL2 LTBP2 A1CF

2.38e-041383938d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFAT HIVEP1 ZFAND4

2.43e-041393937e2c10830c3d16109cab3ed0d64b3532481e497d
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TENM1 BCL9L USO1

2.43e-04139393aefcfda2b2db302ce4b3d2a09f767be0b1c3ac6c
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TENM1 BCL9L USO1

2.43e-04139393b9c2dfab119ac0efdf931bb2910e82bccdb4e48d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 ELAVL1 HSPA4L

2.48e-041403937b359bfbd404ab06d799048252f4985d85852048
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TENM1 DLC1 TMEM184A

2.92e-04148393c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SPTLC3 UNC79 ZFAND4

3.22e-04153393fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SPTLC3 UNC79 ZFAND4

3.22e-041533932482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPTLC3 SORBS1 UNC79

3.41e-041563930f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTLC3 SORBS1 UNC79

3.41e-04156393cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

ZFAT HIVEP1 KIF2C

3.95e-0416439306db4cc064f0765c481ce880207823872c27bfa9
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LTBP2 DACH2 PHYHIPL

3.95e-04164393e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

HIVEP1 DLC1 GJB4

4.23e-0416839300646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ZFAT HIVEP1 KIF2C

4.23e-041683934bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

LTBP2 ZFAT EIF4B

4.23e-04168393c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCelldroplet-Thymus-nan-18m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD42 TMEM184A ANXA13

4.31e-041693934ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

A1CF DACH2 UNC79

4.31e-04169393b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PODXL2 A1CF UNC79

4.31e-0416939396a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A1CF PHYHIPL ANXA13

4.38e-04170393fcaa32607bcbd8be6f040f9487c3d71e976e1077
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 IGF2R MYBL1

4.53e-0417239386f52f486d67217fc1b8443ab362c975df2974a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 IGF2R MYBL1

4.53e-04172393fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 IGF2R MYBL1

4.53e-04172393e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM1 ADAM33 SORBS1

4.61e-04173393f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF ZFAT UNC79

4.61e-041733938888434641ea554a9b62c436e87920378eef29cd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 HIVEP1 DLC1

4.69e-0417439399eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTLC3 ANKRD42 HSPA4L

4.69e-04174393179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTLC3 ANKRD42 HSPA4L

4.69e-041743939165a1094d345328e58962f4b2a20334c3e93ead
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM33 LTBP2 DACH2

4.77e-041753931799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

PODXL2 DACH2 UNC79

4.77e-041753934db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM184A HSPA4L UNC79

4.77e-0417539338dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

PODXL2 DACH2 UNC79

4.77e-041753938d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R MYBL1 KIF2C

4.77e-041753933e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

A1CF DLC1 PHYHIPL

4.85e-041763931e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM1 ADAM33 SORBS1

4.93e-04177393e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM1 HIVEP1 KIF2C

4.93e-04177393ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A1CF PHYHIPL ANXA13

4.93e-041773932af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTLC3 HSPA4L ZFAND4

5.18e-041803935c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTLC3 HSPA4L ZFAND4

5.18e-04180393c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM33 LTBP2 DACH2

5.26e-04181393b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 SORBS1 UNC79

5.35e-04182393d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 SORBS1 UNC79

5.35e-04182393e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 TMEM184A ANXA13

5.43e-041833932df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TENM1 A1CF PHYHIPL

5.43e-041833936878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTLC3 ADAM33 LTBP2

5.43e-041833937eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 TMEM184A ANXA13

5.52e-041843936388c47b7f1d8203e3069eba0e74107256dcae51
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM184A PHYHIPL GJB4

5.52e-04184393e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCelldroplet-Heart-4Chambers-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 TMEM184A ANXA13

5.52e-04184393d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM184A PHYHIPL GJB4

5.52e-04184393c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PELI2 SORBS1 HIVEP1

5.52e-04184393d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM184A PHYHIPL GJB4

5.61e-0418539330263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SORBS1 LTBP2 DACH2

5.61e-04185393e58a009aaf342be019a909747b1895d5987d4daf
ToppCellfacs-Trachea-nan-24m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 TMEM184A GJB4

5.61e-04185393e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM184A PHYHIPL GJB4

5.61e-041853931b000ca11970db8f347eb97ff44605d562aea70a
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SORBS1 A1CF DLC1

5.61e-041853931d874608aa2062024323512f68889219471b2f00
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 SPTLC3 PHYHIPL

5.69e-04186393f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DACH2 PHYHIPL UNC79

5.69e-04186393b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 SPTLC3 PHYHIPL

5.78e-04187393c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

A1CF DLC1 PHYHIPL

5.78e-04187393f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL2 RBM12 KIF2C

5.78e-04187393a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

A1CF ZFAT HSPA4L

5.78e-04187393acd305475f3609800af0d7bc68d83ef41228080b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 SPTLC3 PHYHIPL

5.87e-04188393af740fa78542438fdff627ea1f74f4eee43316be
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SORBS1 LTBP2 DACH2

5.87e-041883934d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RANBP2 IGF2R SIK3

5.87e-04188393ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SORBS1 DLC1

5.87e-04188393b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DACH2 PHYHIPL UNC79

5.87e-04188393c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 A1CF PHYHIPL

5.97e-0418939313fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SORBS1 DLC1

5.97e-041893932cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM1 A1CF PHYHIPL

5.97e-04189393204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TENM1 BCL9L MYBL1

5.97e-041893935a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SORBS1 DLC1

5.97e-04189393127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

PELI2 IGF2R MYBL1

6.06e-041903931584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SORBS1 LTBP2

6.06e-041903932e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SPTLC3 LTBP2 DACH2

6.06e-04190393d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

RANBP2 ZFAND4 MYBL1

6.06e-04190393bfb16efb23add53eebabc8e48f20c96994ec01da
DrugBacitracin [1405-87-4]; Down 200; 2.8uM; HL60; HT_HG-U133A

SPTLC3 NEK1 A1CF DLC1 IDH3G NAB2

1.03e-061983963109_DN
Diseasebody surface area

LTBP2 ZFAT HIVEP1 DLC1 FEZ2 UNC79

1.85e-04643396EFO_0022196
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

A1CF RBM12 IGF2R

4.29e-04111393EFO_0004530, EFO_0008595
Diseasestimulant use measurement

HIVEP1 DLC1

6.30e-0428392EFO_0600076
Diseaseoxalate measurement

SORBS1 DLC1

8.23e-0432392EFO_0010517
Diseasemultiple myeloma (is_marker_for)

RANBP2 IGF2R

1.04e-0336392DOID:9538 (is_marker_for)
Diseasecholesteryl esters to total lipids in medium LDL percentage

IGF2R SIK3

1.10e-0337392EFO_0022252
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

HIVEP1 SSH2 FEZ2 UNC79

1.33e-03364394EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasetriglycerides in large LDL measurement

IGF2R SIK3

1.49e-0343392EFO_0022319
Diseasephospholipids in medium VLDL measurement

IGF2R SIK3

2.16e-0352392EFO_0022154
Diseasetotal lipids in medium VLDL

IGF2R SIK3

2.33e-0354392EFO_0022153
Diseasenon-high density lipoprotein cholesterol measurement

A1CF HIVEP1 IGF2R DLC1 USO1

2.37e-03713395EFO_0005689
Diseasetriacylglycerol 52:2 measurement

ZFAT SIK3

2.42e-0355392EFO_0010414
Diseasetriglycerides in LDL measurement

IGF2R SIK3

2.51e-0356392EFO_0022320
Diseasetriglycerides in IDL measurement

IGF2R SIK3

2.69e-0358392EFO_0022149
Diseasephospholipids in VLDL measurement

IGF2R SIK3

2.78e-0359392EFO_0022301
Diseasetotal lipids in VLDL measurement

IGF2R SIK3

2.87e-0360392EFO_0022314
Diseasefree cholesterol in VLDL measurement

IGF2R SIK3

2.97e-0361392EFO_0022276
Diseasetriglycerides in medium LDL measurement

IGF2R SIK3

3.06e-0362392EFO_0022322
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

A1CF RBM12 IGF2R

3.07e-03220393EFO_0004529, EFO_0008317
Diseasecholesterol in very large VLDL measurement

IGF2R SIK3

3.36e-0365392EFO_0022230
Diseasecholesterol in large VLDL measurement

IGF2R SIK3

3.36e-0365392EFO_0021902
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

RBM12 IGF2R SIK3

3.43e-03229393EFO_0004639, EFO_0008317
Diseasetotal lipids in small VLDL

IGF2R SIK3

3.56e-0367392EFO_0022148
Diseasetriglycerides in very small VLDL measurement

IGF2R SIK3

3.67e-0368392EFO_0022144
Diseasebody fat percentage

HIVEP1 SSH2 FEZ2 UNC79

3.85e-03488394EFO_0007800
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

IGF2R SIK3

4.80e-0378392EFO_0022187
Diseasevery low density lipoprotein cholesterol measurement

A1CF IGF2R SIK3

4.89e-03260393EFO_0008317

Protein segments in the cluster

PeptideGeneStartEntry
MESNHKSGDGLSGTQ

A1CF

1

Q9NQ94
GGSMDSGPVQAENHD

ADAM33

686

Q9BZ11
MGNRHAKASSPQGFD

ANXA13

1

P27216
ENNGTPHDSAAMQGG

DACH2

571

Q96NX9
RADNGSTPMHKAAGQ

ANKRD42

266

Q8N9B4
GGHITFKQNMGPSGQ

RBM12

386

Q9NTZ6
KHTGPGLLSMANQGQ

RANBP2

3151

P49792
QSEMQEKHPSLNGGG

PODXL2

561

Q9NZ53
LGQHETGGSPSKQQM

NEK1

656

Q96PY6
MSNGHGSPGEKAGSA

NAB2

141

Q15742
DHMSGLSGVNVPGNA

ELAVL1

226

Q15717
MDNENMHTPDIGGQG

IDH3G

356

P51553
GAGNHGAKANQISPS

BCL9L

76

Q86UU0
QGGHPEDGNSVLMKA

GJB4

241

Q9NTQ9
AGGQSMSEAPTGDHA

LTBP2

1391

Q14767
KGHSPNIFGSSQMGA

MAN1A2

211

O60476
HTMGGDLSGKAQNAS

KIF2C

356

Q99661
GSLNDGGNMALKHTP

MYBL1

466

P10243
GSSQNGKNERSHMPG

FEZ2

286

Q9UHY8
DGMNAPKGQTGNSSR

EIF4B

531

P23588
SENPGDDGQMHKGLS

IGF2R

2286

P11717
HHGNAMQPSVKDNSG

PHYHIPL

201

Q96FC7
GVMGGQSAGPQHTEA

USO1

6

O60763
AGPQMDHMGNSSQGA

TMEM184A

31

Q6ZMB5
KNPDGHMDGLTTNGV

PELI2

176

Q9HAT8
HMNQGDAGSLAPSLG

SIK3

1021

Q9Y2K2
PQSGIIHKGNGENMF

TENM1

1146

Q9UKZ4
MANPGGGAVCNGKLH

SPTLC3

1

Q9NUV7
QGQKTSGQHMIQGAG

DLC1

131

Q96QB1
ESHGAQSPLGEGQNM

ZFAT

646

Q9P243
QEGDDSMGKKHSGSQ

TPRX1

376

Q8N7U7
SMGKKHSGSQPQEEG

TPRX1

381

Q8N7U7
KDGPMGNSGGNHVAV

ZFHX2

221

Q9C0A1
GEQELQGSGMHPGAK

SSH2

846

Q76I76
KANSEHNGPMDGQSG

HSPA4L

801

O95757
HNGPMDGQSGTETKS

HSPA4L

806

O95757
AAAAAAQMHAKNGGG

SOGA3

271

Q5TF21
AVMNGLAPGSNGQDK

SORBS1

11

Q9BX66
PTSQASLHMNGDGGV

SORBS1

1066

Q9BX66
SGAHLPGNKENNSNM

XKR3

286

Q5GH77
THGVGMNGNNAAAGK

ZFAND4

626

Q86XD8
GDMNPLEGKQDSHVG

HIVEP1

626

P15822
TMNQGDDGPSGKNAA

UNC79

1651

Q9P2D8