Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

MXD3 ZNF845 ZNF777 ZNF142 ZNF143 HOXC13 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ETV2 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ST18

1.65e-0514129119GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

MXD3 ZNF845 ZNF777 ZNF142 ZNF143 HOXC13 ZNF718 ZNF648 ZNF764 INSM1 ETV2 ZNF808 ZNF525 NFKBIZ ZNF578 ZNF799 ZNF224 ZNF865 ST18

2.60e-0514599119GO:0000977
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

MXD3 ZNF845 ZNF143 HOXC13 ZNF718 ZNF648 ZNF764 INSM1 ETV2 ZNF808 ZNF525 NFKBIZ HMGB2 ZNF578 ZNF224 ZNF865 ST18

5.35e-0512719117GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

MXD3 ZNF845 ZNF143 HOXC13 ZNF718 ZNF648 ZNF764 INSM1 ETV2 ZNF808 ZNF525 NFKBIZ ZNF578 ZNF224 ZNF865 ST18

1.44e-0412449116GO:0000978
GeneOntologyMolecularFunctiontranscription coregulator activity

CIITA ZNF764 ZMIZ2 ZNF451 NAB2 NFKBIZ HMGB2 RCOR3 RAD54L2 CBFA2T3

2.39e-045629110GO:0003712
GeneOntologyMolecularFunctionnodal binding

LEFTY2 LEFTY1

5.65e-048912GO:0038100
GeneOntologyMolecularFunctionmolecular adaptor activity

CIITA ZNF764 ZMIZ2 ZNF451 NAB2 INSM1 NFKBIZ HMGB2 RCOR3 CARD10 RAD54L2 CBFA2T3 KLHDC10 KIR3DL2 TAPBP

1.15e-0313569115GO:0060090
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

LEFTY2 LEFTY1 NCLN

2.59e-067883GO:1900108
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

LEFTY2 LEFTY1 NCLN

6.19e-069883GO:1900107
GeneOntologyBiologicalProcessnegative regulation of nodal receptor complex assembly

LEFTY2 LEFTY1

1.80e-052882GO:1900124
GeneOntologyBiologicalProcessregulation of nodal receptor complex assembly

LEFTY2 LEFTY1

1.80e-052882GO:1900123
GeneOntologyBiologicalProcessnodal receptor complex assembly

LEFTY2 LEFTY1

1.80e-052882GO:0038099
GeneOntologyBiologicalProcessgamma-tubulin complex localization

CEP72 ZNF365

5.38e-053882GO:0033566
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

LEFTY2 LEFTY1 NCLN

9.44e-0521883GO:0032926
GeneOntologyBiologicalProcessnodal signaling pathway

LEFTY2 LEFTY1 NCLN

1.82e-0426883GO:0038092
MousePhenoleft atrial isomerism

LEFTY2 LEFTY1 INVS

4.81e-068633MP:0008461
MousePhenoabnormal left renal vein morphology

LEFTY2 LEFTY1

2.00e-052632MP:0011327
MousePhenoabnormal renal vein morphology

LEFTY2 LEFTY1

2.00e-052632MP:0011323
MousePhenoabnormal heart atrium arrangement

LEFTY2 LEFTY1 INVS

5.67e-0517633MP:0014319
MousePhenoabnormal kidney venous blood vessel morphology

LEFTY2 LEFTY1

5.98e-053632MP:0011311
MousePhenoabnormal large intestine placement

LEFTY2 LEFTY1

1.19e-044632MP:0003284
MousePhenouterus inflammation

METRNL TNFAIP3

1.98e-045632MP:0009080
DomainZnf_C2H2

ZNF845 ZNF777 ZNF142 ZNF143 ZNF474 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865 ZNF365

6.05e-098058919IPR007087
DomainZINC_FINGER_C2H2_2

ZNF845 ZNF777 ZNF142 ZNF143 ZNF474 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865

2.08e-087758918PS50157
DomainZINC_FINGER_C2H2_1

ZNF845 ZNF777 ZNF142 ZNF143 ZNF474 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865

2.16e-087778918PS00028
DomainZnF_C2H2

ZNF845 ZNF777 ZNF142 ZNF143 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865 ZNF365

3.92e-088088918SM00355
Domainzf-C2H2

ZNF845 ZNF777 ZNF142 ZNF143 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF865

1.54e-076938916PF00096
DomainZnf_C2H2-like

ZNF845 ZNF777 ZNF142 ZNF143 ZNF718 ZNF648 ZNF764 ZNF451 INSM1 ZNF808 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865 ZNF365

1.81e-077968917IPR015880
Domain-

ZNF845 ZNF777 ZNF142 ZNF143 ZNF718 ZNF648 ZNF764 INSM1 ZNF808 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865

6.90e-0767989153.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF845 ZNF777 ZNF142 ZNF143 ZNF718 ZNF648 ZNF764 INSM1 ZNF808 ZNF578 ZNF799 ZNF224 ZNF579 ZNF831 ZNF865

9.07e-076948915IPR013087
DomainLRDF

LEFTY2 LEFTY1

2.25e-052892IPR003942
DomainKRAB

ZNF845 ZNF777 ZNF718 ZNF764 ZNF808 ZNF578 ZNF799 ZNF224

3.08e-04358898PS50805
DomainKRAB

ZNF845 ZNF777 ZNF718 ZNF764 ZNF808 ZNF578 ZNF799 ZNF224

3.08e-04358898PF01352
DomainKRAB

ZNF845 ZNF777 ZNF718 ZNF764 ZNF808 ZNF578 ZNF799 ZNF224

3.78e-04369898SM00349
DomainKRAB

ZNF845 ZNF777 ZNF718 ZNF764 ZNF808 ZNF578 ZNF799 ZNF224

3.84e-04370898IPR001909
DomainGal_Oxidase_b-propeller

KLHL36 GAN KLHDC10

5.62e-0434893IPR015916
DomainMetalloPept_cat_dom

ADAMTS10 MMP24 ADAMTS16 MMP17

6.06e-0481894IPR024079
Domain-

ADAMTS10 MMP24 ADAMTS16 MMP17

6.06e-04818943.40.390.10
Domainzf-C2H2_6

ZNF845 ZNF718 ZNF808 ZNF578 ZNF799 ZNF224 ZNF865

7.53e-04314897PF13912
DomainCYSTEINE_SWITCH

MMP24 ADAMTS16 MMP17

9.78e-0441893PS00546
DomainPept_M10_metallopeptidase

MMP24 ADAMTS16 MMP17

1.12e-0343893IPR001818
DomainZINC_PROTEASE

ADAMTS10 MMP24 ADAMTS16 MMP17

1.24e-0398894PS00142
DomainPLAC

ADAMTS10 ADAMTS16

1.97e-0314892PF08686
DomainKelch-typ_b-propeller

KLHL36 GAN KLHDC10

2.29e-0355893IPR015915
DomainKelch

KLHL36 GAN KLHDC10

2.67e-0358893SM00612
DomainPept_M10A_stromelysin-type

MMP24 MMP17

3.27e-0318892IPR016293
DomainTSP_1

ADAMTS10 ADAMTS16 THSD1

3.38e-0363893PF00090
DomainPLAC

ADAMTS10 ADAMTS16

3.64e-0319892PS50900
DomainPLAC

ADAMTS10 ADAMTS16

3.64e-0319892IPR010909
DomainTSP1

ADAMTS10 ADAMTS16 THSD1

3.69e-0365893SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTS16 THSD1

3.69e-0365893IPR000884
DomainTSP1

ADAMTS10 ADAMTS16 THSD1

3.69e-0365893PS50092
DomainPG_binding_1

MMP24 MMP17

4.03e-0320892PF01471
DomainPeptidoglycan-bd-like

MMP24 MMP17

4.03e-0320892IPR002477
DomainKelch_1

KLHL36 GAN KLHDC10

4.55e-0370893PF01344
DomainKelch_1

KLHL36 GAN KLHDC10

4.55e-0370893IPR006652
DomainADAM_spacer1

ADAMTS10 ADAMTS16

5.32e-0323892IPR010294
DomainHemopexin-like_dom

MMP24 MMP17

5.32e-0323892IPR000585
DomainHemopexin-like_repeat

MMP24 MMP17

5.32e-0323892IPR018487
DomainM10A_MMP

MMP24 MMP17

5.32e-0323892IPR033739
DomainADAM_spacer1

ADAMTS10 ADAMTS16

5.32e-0323892PF05986
DomainHemopexin

MMP24 MMP17

5.32e-0323892PF00045
DomainHEMOPEXIN

MMP24 MMP17

5.32e-0323892PS00024
Domain-

MMP24 MMP17

5.32e-03238922.110.10.10
DomainHEMOPEXIN_2

MMP24 MMP17

5.32e-0323892PS51642
DomainHX

MMP24 MMP17

5.32e-0323892SM00120
DomainPept_M10A

MMP24 MMP17

5.32e-0323892IPR021190
DomainPeptidase_M10

MMP24 MMP17

5.79e-0324892PF00413
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTS16

5.79e-0324892IPR013273
DomainANK_REPEAT

ASB10 MUC16 NFKBIZ TEX14 INVS

7.23e-03253895PS50088
DomainANK_REP_REGION

ASB10 MUC16 NFKBIZ TEX14 INVS

7.35e-03254895PS50297
DomainTGFb_propeptide

LEFTY2 LEFTY1

7.83e-0328892PF00688
DomainTGF-b_N

LEFTY2 LEFTY1

7.83e-0328892IPR001111
DomainZnMc

MMP24 MMP17

8.38e-0329892SM00235
DomainPeptidase_Metallo

MMP24 MMP17

8.38e-0329892IPR006026
Pubmed

Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos.

LEFTY2 LEFTY1 INVS

7.15e-0849239348041
Pubmed

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos.

LEFTY2 LEFTY1 INVS

7.15e-0849238610011
Pubmed

Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2.

LEFTY2 LEFTY1 INVS

7.15e-0849239990851
Pubmed

Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer.

LEFTY2 LEFTY1 INVS

1.78e-07592310385627
Pubmed

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2.

LEFTY2 LEFTY1 INVS

3.56e-07692310678167
Pubmed

Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.

LEFTY2 LEFTY1 INVS

6.22e-07792319906859
Pubmed

Molecular mechanisms of vertebrate left-right development.

LEFTY2 LEFTY1 INVS

6.22e-0779239825674
Pubmed

Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.

LEFTY2 LEFTY1 INVS

9.94e-07892315736223
Pubmed

Apoptosis in the fetal testis eliminates developmentally defective germ cell clones.

LEFTY2 LEFTY1 TEX14

2.91e-061192333199844
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STK36 STARD8 CEP72 EEPD1 ADAMTS16 CEP152 LRRC14 KLHDC10 CCDC85A

6.59e-0649392915368895
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

STK36 DNAJC14 KLHL36 ZMIZ2 CARD10 LRRC14 TNFAIP3 ZNF579 NCLN MMP17 RGL2 ZNF865 UVRAG

6.85e-061105921335748872
Pubmed

Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.

LEFTY2 LEFTY1

6.92e-06292220171171
Pubmed

Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.

LEFTY2 LEFTY1

6.92e-0629229496783
Pubmed

A functional role of LEFTY during progesterone therapy for endometrial carcinoma.

LEFTY2 LEFTY1

6.92e-06292229268772
Pubmed

Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway.

LEFTY2 LEFTY1

6.92e-06292229286065
Pubmed

LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.

LEFTY2 LEFTY1

6.92e-06292232745796
Pubmed

Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.

LEFTY2 LEFTY1

6.92e-06292224147624
Pubmed

Isolation, characterization, and function of EBAF/LEFTY B: role in infertility.

LEFTY2 LEFTY1

6.92e-06292221401636
Pubmed

Lefty1 Ameliorates Post-infarction Fibrosis by Suppressing p-Smad2 and p-ERK1/2 Signaling Pathways.

LEFTY2 LEFTY1

6.92e-06292233409963
Pubmed

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry.

LEFTY2 LEFTY1

6.92e-06292229230527
Pubmed

Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts.

MMP24 MMP17

6.92e-06292210471807
Pubmed

LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.

LEFTY2 LEFTY1

6.92e-06292220056823
Pubmed

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

LEFTY2 LEFTY1

6.92e-06292210053005
Pubmed

Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period.

LEFTY2 LEFTY1

6.92e-06292215640253
Pubmed

Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.

LEFTY2 LEFTY1

6.92e-06292211100524
Pubmed

Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.

LEFTY2 LEFTY1

6.92e-06292217038673
Pubmed

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.

LEFTY2 LEFTY1 PCSK7

9.78e-061692320876279
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

GEN1 UVRAG CACNA2D3

9.78e-061692316096065
Pubmed

Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos.

LEFTY2 LEFTY1 INVS

9.78e-061692311900971
Pubmed

Two modes by which Lefty proteins inhibit nodal signaling.

LEFTY2 LEFTY1

2.07e-05392215062104
Pubmed

Nodal and lefty signaling regulates the growth of pancreatic cells.

LEFTY2 LEFTY1

2.07e-05392218393305
Pubmed

Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system.

LEFTY2 LEFTY1

2.07e-05392217011489
Pubmed

Lefty-1 inhibits renal epithelial-mesenchymal transition by antagonizing the TGF-β/Smad signaling pathway.

LEFTY2 LEFTY1

2.07e-05392232065356
Pubmed

Lefty-1 alleviates TGF-β1-induced fibroblast-myofibroblast transdifferentiation in NRK-49F cells.

LEFTY2 LEFTY1

2.07e-05392226316705
Pubmed

Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.

LEFTY2 LEFTY1

2.07e-05392233111989
Pubmed

Role of asymmetric signals in left-right patterning in the mouse.

LEFTY2 LEFTY1

2.07e-05392211471154
Pubmed

Lefty1 alleviates renal tubulointerstitial injury in mice with unilateral ureteral obstruction.

LEFTY2 LEFTY1

2.07e-05392226647776
Pubmed

TGFβ signaling in establishing left-right asymmetry.

LEFTY2 LEFTY1

2.07e-05392224704359
Pubmed

Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.

LEFTY2 LEFTY1

2.07e-05392216141390
Pubmed

IFT46 plays an essential role in cilia development.

LEFTY2 LEFTY1

2.07e-05392225722189
Pubmed

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein.

LEFTY2 LEFTY1

2.07e-0539229865700
Pubmed

Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes.

LEFTY2 LEFTY1

2.07e-05392210886363
Pubmed

Nodal activates smad and extracellular signal-regulated kinases 1/2 pathways promoting renal cell carcinoma proliferation.

LEFTY2 LEFTY1

2.07e-05392225672326
Pubmed

Assignment of the genes for membrane-type-4 matrix metalloproteinase (Mmp17, MMP17) to mouse chromosome 5, human chromosome band 12q24.3 and membrane-type-5 matrix metalloproteinase (Mmp24, MMP24) to mouse chromosome 2 and human chromosome band 20q11.2-->q12, respectively, by radiation hybrid and in situ hybridization.

MMP24 MMP17

2.07e-05392210640822
Pubmed

Novel Helicobacter species H.japonicum isolated from laboratory mice from Japan induces typhlocolitis and lower bowel carcinoma in C57BL/129 IL10-/- mice.

LEFTY2 LEFTY1

2.07e-05392227655833
Pubmed

Association of maternal hypertension and diabetes with variants of the NKX2-5, LEFTY1 and LEFTY2 genes in children with congenital heart defects: a case-control study from Pakistani Population.

LEFTY2 LEFTY1

2.07e-05392237097539
Pubmed

Embryonic asymmetry: the left side gets all the best genes.

LEFTY2 LEFTY1

2.07e-0539229889116
Pubmed

A20 is a negative regulator of BCL10- and CARMA3-mediated activation of NF-kappaB.

CARD10 TNFAIP3

2.07e-05392218349075
Pubmed

Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements.

LEFTY2 LEFTY1

4.14e-05492215454269
Pubmed

NIK is a component of the EGF/heregulin receptor signaling complexes.

MAP3K14 GRB7

4.14e-05492212853971
Pubmed

Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry.

LEFTY2 LEFTY1

4.14e-0549229708732
Pubmed

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.

LEFTY2 LEFTY1

4.14e-0549229708731
Pubmed

A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes.

MAP3K14 TNFAIP3

4.14e-05492232028675
Pubmed

The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.

LEFTY2 LEFTY1

4.14e-05492223544137
Pubmed

The role of the brachyury gene in heart development and left-right specification in the mouse.

LEFTY2 LEFTY1

4.14e-05492210349618
Pubmed

Calaxin is required for cilia-driven determination of vertebrate laterality.

LEFTY2 LEFTY1

4.14e-05492231240264
Pubmed

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.

LEFTY2 LEFTY1

4.14e-05492211448943
Pubmed

The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation.

LEFTY2 LEFTY1

4.14e-05492217662710
Pubmed

The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness.

LEFTY2 LEFTY1

4.14e-0549229376323
Pubmed

Wnt3a-dependent and -independent protein interaction networks of chromatin-bound β-catenin in mouse embryonic stem cells.

LEFTY2 LEFTY1

4.14e-05492223592333
Pubmed

LEFTYA Activates the Epithelial Na+ Channel (ENaC) in Endometrial Cells via Serum and Glucocorticoid Inducible Kinase SGK1.

LEFTY2 LEFTY1

4.14e-05492227606670
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 LEFTY2 LEFTY1 ADAMTS16

4.83e-057592420637190
Pubmed

Lineage-specific functions of TET1 in the postimplantation mouse embryo.

LEFTY2 LEFTY1

6.89e-05592228504700
Pubmed

Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2.

LEFTY2 LEFTY1

6.89e-05592211703930
Pubmed

mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.

MMP24 MMP17

6.89e-05592212661033
Pubmed

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development.

LEFTY2 LEFTY1

6.89e-05592215750185
Pubmed

Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.

LEFTY2 LEFTY1

6.89e-05592215308665
Pubmed

Smad5 is essential for left-right asymmetry in mice.

LEFTY2 LEFTY1

6.89e-05592210677256
Pubmed

The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells.

LEFTY2 LEFTY1

6.89e-05592221266536
Pubmed

Regulation of left-right patterning in mice by growth/differentiation factor-1.

LEFTY2 LEFTY1

6.89e-05592210700179
Pubmed

Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.

LEFTY2 LEFTY1

6.89e-05592217075880
Pubmed

Nodal signaling regulates the entry into meiosis in fetal germ cells.

LEFTY2 LEFTY1

6.89e-05592222396454
Pubmed

Foxj1 regulates asymmetric gene expression during left-right axis patterning in mice.

LEFTY2 LEFTY1

6.89e-05592215504371
Pubmed

Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation.

LEFTY2 LEFTY1

6.89e-05592226348837
Pubmed

Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate.

LEFTY2 LEFTY1

6.89e-05592212642485
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MBD1 MAP3K14 OSBPL10 GAN CEP152 TNFAIP3 LARP1B RGL2 GEN1 UVRAG

9.49e-05861921036931259
Pubmed

Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH.

LEFTY2 LEFTY1

1.03e-04692210411502
Pubmed

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.

LEFTY2 LEFTY1

1.03e-04692210500184
Pubmed

Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.

LEFTY2 LEFTY1

1.03e-04692210603343
Pubmed

Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation.

LEFTY2 LEFTY1

1.03e-04692232579954
Pubmed

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates.

LEFTY2 LEFTY1

1.03e-04692218039650
Pubmed

A role of the cryptic gene in the correct establishment of the left-right axis.

LEFTY2 LEFTY1

1.03e-04692210574770
Pubmed

Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo.

LEFTY2 LEFTY1

1.03e-04692215004567
Pubmed

Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm.

LEFTY2 LEFTY1

1.03e-04692221364967
Pubmed

Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.

ADAMTS10 RGL2 TAPBP

1.20e-043692315112104
Pubmed

The mouse embryo autonomously acquires anterior-posterior polarity at implantation.

LEFTY2 LEFTY1

1.44e-04792216580991
Pubmed

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.

LEFTY2 LEFTY1

1.44e-04792215121860
Pubmed

Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC.

RGL2 TAPBP

1.44e-0479229521053
Pubmed

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.

LEFTY2 LEFTY1

1.44e-04792232876567
Pubmed

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.

LEFTY2 LEFTY1

1.44e-04792210521397
Pubmed

Retinoic acid affects left-right patterning.

LEFTY2 LEFTY1

1.44e-04792210545241
Pubmed

Membrane-type matrix metalloproteinases: Their functions and regulations.

MMP24 MMP17

1.44e-04792225794647
Pubmed

The ion channel polycystin-2 is required for left-right axis determination in mice.

LEFTY2 LEFTY1

1.44e-04792212062060
Pubmed

The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis.

LEFTY2 LEFTY1

1.44e-04792215466485
Pubmed

The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination.

LEFTY2 LEFTY1

1.44e-04792210804177
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

CAD ZNF451 RCOR3 RAD54L2

1.85e-0410692419394292
Pubmed

Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.

LEFTY2 LEFTY1

1.92e-04892221802298
Pubmed

TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.

RGL2 TAPBP

1.92e-0489229545376
Pubmed

Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects.

LEFTY2 LEFTY1

1.92e-04892218773491
Pubmed

Nodal signaling and axis formation in the mouse.

LEFTY2 LEFTY1

1.92e-0489229598342
Cytoband19q13.42

ZNF845 ZNF525 ZNF579 ZNF865

1.22e-0412592419q13.42
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF845 VSIG10L ETV2 ZNF808 ZNF525 ZNF578 ZNF224 ZNF579 KIR3DL2 ZNF865

1.41e-0411929210chr19q13
Cytoband20p11.2

CRNKL1 INSM1

2.16e-041192220p11.2
Cytoband1q42.1

LEFTY2 LEFTY1

2.59e-04129221q42.1
Cytoband19q13.41

VSIG10L ZNF808 ZNF578

5.31e-047892319q13.41
Cytoband16q24.1

KLHL36 GAN

2.01e-033392216q24.1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF845 ZNF777 ZNF142 ZNF143 ZNF474 ZNF718 ZNF648 ZNF764 ZNF451 ZNF808 ZNF525 ZNF578 ZNF799 ZNF224 ZNF579 ZNF865 ZNF365

5.12e-10718661728
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXD3 FBLN7 ARHGEF39 HMGB2 CEP152 GEN1

2.37e-0618592630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXD3 FBLN7 ARHGEF39 HMGB2 CEP152 GEN1

2.52e-061879269351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ADAMTS10 RNF214 IQCC ZNF578 INVS AGBL3

3.21e-061959261e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXD3 CIITA HMGB2 THSD1 CCDC85A

2.24e-051639257864e966c228282b4b63c43164dba3faba21026d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF39 CEP72 PPP1R18 GAN HMGB2

2.44e-05166925a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

CIITA MAP3K14 CBFA2T3 ST18 UVRAG

2.82e-051719256a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCellChildren_(3_yrs)-Immune-dendritic_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CIITA MAP3K14 CBFA2T3 ST18 UVRAG

2.82e-051719256a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANO9 FBLN7 MAP3K14 ZNF831 TIGD6

3.06e-051749257ca39c9ecd609e5ade30dac1a948a4a4fff1b3b2
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MXD3 ARHGEF39 HMGB2 CARD10 LARP1B

3.32e-05177925b41e975e8368e2618b015be095efe8c0e001c78b
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MXD3 ARHGEF39 HMGB2 CARD10 LARP1B

3.32e-0517792515d1de38e4f1a0d4a786d83ee92240f44bdff006
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXD3 ARHGEF39 HMGB2 CEP152 GEN1

3.60e-05180925334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

ZNF845 DNAJC14 KLHL36 OSBPL10 PTK6

3.69e-0518192569eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXD3 IQCC ARHGEF39 HMGB2 AGBL3

3.69e-05181925e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

CIITA MAP3K14 CBFA2T3 ST18 UVRAG

3.89e-05183925703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRM EEPD1 CHDH THSD1 CCDC85A

3.89e-05183925e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

CIITA MAP3K14 CBFA2T3 ST18 UVRAG

3.89e-05183925b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCell(3)_DC_activated|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MMP24 CIITA INSM1 MAP3K14 UVRAG

4.54e-05189925e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXD3 ARHGEF39 HMGB2 CEP152 GEN1

4.54e-051899251e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

CIITA HMGB2 CBFA2T3 ST18 CACNA2D3

4.77e-05191925aa9c0b1b90cdb7a95d4e6332819f82cae0a79ff9
ToppCellCOVID-mDC2|COVID / Condition, Cell_class and T cell subcluster

CIITA METRNL ST18 UVRAG CACNA2D3

5.39e-05196925bb13926bb664be917017edb0ce7f184abe31744b
ToppCellCOVID-mDC2-|COVID / Condition, Cell_class and T cell subcluster

CIITA METRNL ST18 UVRAG CACNA2D3

5.39e-051969256d02a4c5c19be7e036150cf945585cf5a773bc87
ToppCell(2)_NK/T-(231)_CD4+/CD45RO+_Memory_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

RNF214 ANO9 EEPD1 HMGB2 TNFAIP3

5.39e-051969255267acead12207f238d9afa3eef8ac1168b47082
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANO9 FBLN7 PCSK7 TNFAIP3 ZNF831

5.52e-05197925e60deb009238702110c3b0948778802df215ad74
ToppCellMonocytes-cDCs|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

CIITA CBFA2T3 ST18 UVRAG CACNA2D3

5.52e-0519792515cb9fe1c3bab80bd24728fd9ac7ba385912ac33
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

MXD3 ARHGEF39 ZNF808 HMGB2 GEN1

5.52e-05197925038fd92750257d43d5e980fd06d77742b543f11a
ToppCellsevere-B_memory|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CIITA OSBPL10 CBFA2T3 GEN1 UVRAG

5.79e-051999256d3436dd65d525aaa23ec02672005380f21c4d0f
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MXD3 ARHGEF39 HMGB2 CEP152 GEN1

5.79e-0519992598575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MXD3 ARHGEF39 HMGB2 CEP152 GEN1

5.79e-05199925be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

MXD3 ARHGEF39 HMGB2 CEP152 GEN1

5.93e-052009259bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellsevere-B_intermediate|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CIITA OSBPL10 CBFA2T3 GEN1 UVRAG

5.93e-052009256d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MXD3 ARHGEF39 EEPD1 HMGB2 GEN1

5.93e-05200925ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FBLN7 DNAJC14 ZNF718 NFKBIZ

1.48e-041299242f30b4897343586c9b49a1d2bec3007ec737085c
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MXD3 ARHGEF39 TYMSOS HMGB2

2.57e-0414992489faa84af68d4727180f39718964bb3bc65d8fe6
ToppCell368C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO9 PTPRM RGL2 GEN1

2.92e-04154924f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell368C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO9 PTPRM RGL2 GEN1

2.92e-0415492466065c0763c83d98084ca6969694c3af37e43274
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CIITA TEX14 CBFA2T3 ST18

2.99e-041559249f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MMP24 FBLN7 EEPD1 TEX14

2.99e-04155924216a240bfb82cdefc59e2f342689dbaaacb7c184
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

MXD3 ARHGEF39 CACNA2D3 INVS

3.07e-0415692463b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CIITA CBFA2T3 ST18 CACNA2D3

3.14e-04157924e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

CIITA CBFA2T3 ST18 CACNA2D3

3.14e-04157924ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CIITA CBFA2T3 ST18 CACNA2D3

3.22e-04158924e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 PPP1R18 TEX14 ZNF831

3.22e-04158924b1b1e50ddd231dcd10cc8e6bb68b2a5e0bb1450a
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MARCHF10 IQCC CHDH AGBL3

3.22e-0415892474aa4f75307575ac3b2b1aa9f727753692f88742
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA ARHGEF39 CBFA2T3 GEN1

3.22e-0415892491d265e95156f16459924d3e4dd11c180e164eee
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL PPP1R18 KIR3DL2 ZNF365

3.29e-0415992457df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

ZNF764 EEPD1 THSD1 INVS

3.37e-04160924a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

LEFTY2 ADAMTS16 GRB7 KIR3DL2

3.45e-0416192466554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CIITA MAP3K14 CBFA2T3 ST18

3.45e-04161924cd41abb7ae659d3d314281783a0aaad562b26037
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF799 ZNF224 KIR3DL2 CCDC85A

3.54e-0416292445be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF799 ZNF224 KIR3DL2 CCDC85A

3.54e-04162924fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MARCHF10 EEPD1 GRB7 CACNA2D3

3.54e-04162924373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXD3 ARHGEF39 HMGB2 GEN1

3.62e-041639245285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

PTPRM CARD10 THSD1 CCDC85A

3.62e-04163924d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellBronchial_Brush-Epithelial-Goblet_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ARHGEF39 VSIG10L ZNF579 MMP17

3.88e-041669248ac0a769be886d16642e7e6334471ebadd1a426b
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEPD1 ADAMTS16 ZNF865 UVRAG

3.88e-04166924a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCellfacs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEPD1 ADAMTS16 ZNF865 UVRAG

3.88e-041669240f641302a6b71c4badaaf20f51162bfc2386b167
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 TNFAIP3 GEN1

3.97e-04167924e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 TNFAIP3 GEN1

3.97e-04167924b25646b6653cd8814dbeae4c74ce899ede105200
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA ARHGEF39 ZMIZ2 INSM1

4.06e-041689240e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

METRNL MAP3K14 NFKBIZ CBFA2T3

4.06e-041689244b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

METRNL MAP3K14 NFKBIZ CBFA2T3

4.06e-04168924689c41f6e9f65381570991cc311cba49a57ec955
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CIITA CBFA2T3 ST18 UVRAG

4.15e-04169924b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXD3 ARHGEF39 HMGB2 GEN1

4.15e-04169924e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF39 CEP72 HMGB2 CEP152

4.15e-04169924a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CIITA CBFA2T3 ST18 UVRAG

4.15e-041699242322f03a115c662f808ebfc892192b7d38d48181
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 CHDH UVRAG

4.24e-04170924749144a1a869a6bf9acdd227184319083367dc3f
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 CHDH UVRAG

4.24e-0417092425d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LEFTY1 ZMIZ2 EEPD1 CHDH

4.34e-041719242dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LEFTY1 ZMIZ2 EEPD1 CHDH

4.34e-041719242aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXD3 ARHGEF39 GRB7 HMGB2

4.43e-04172924ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS10 LEFTY1 FBLN7 NCLN

4.43e-04172924de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PTPRM ZNF451 MMP17

4.43e-041729241f335ccb92b22d0412954e8fc3af212f96410b67
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LEFTY1 EEPD1 CHDH UVRAG

4.43e-04172924422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 TNFAIP3 ZNF831 GEN1

4.43e-04172924ce444463f69bbb05c933615a0f1f43ddde3eee1c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 TNFAIP3 ZNF831 GEN1

4.43e-041729242c993a93ac91dcf6061eec001f51f8cccb6ee264
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANO9 ASIC1 MUC16 TAPBP

4.43e-041729249a256db817c1af1802203cc88a55d608fb328c63
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

ZNF474 OSBPL10 GRB7 MUC16

4.43e-041729240ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PTPRM ZNF451 MMP17

4.43e-04172924bb96c896d125e10b71e94e2bdad243899045af5c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LEFTY1 EEPD1 CHDH UVRAG

4.43e-041729241abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCelldroplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 CHDH UVRAG

4.53e-041739241b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCelldroplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 ZMIZ2 EEPD1 CHDH

4.53e-041739248fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CIITA CBFA2T3 ST18 UVRAG

4.53e-0417392473f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCelldroplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 EEPD1 CHDH UVRAG

4.53e-04173924c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCelldroplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LEFTY1 ZMIZ2 EEPD1 CHDH

4.53e-04173924f663571aaae2365660a8b526c355f4bd1a124a74
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD8 METRNL NFKBIZ MMP17

4.73e-04175924cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CIITA OSBPL10 GEN1 UVRAG

4.73e-04175924eaec7fda07a9537d067ca13b607a8ab201caa7c4
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CIITA METRNL TNFAIP3 CACNA2D3

4.84e-04176924a31d7532f8c055d4e62bbaa78d819f2495bfee00
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF39 HMGB2 ZNF831 GEN1

4.84e-041769241f8d5a48fedbb4c86272c9b5a0f1ef573350357b
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CIITA INSM1 MAP3K14 CBFA2T3

4.94e-04177924d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CIITA INSM1 MAP3K14 UVRAG

4.94e-04177924aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCellfacs-BAT-Fat-3m-Epithelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASIC1 GRB7 ZNF579 AGBL3

4.94e-041779243e42f6236962dd9bb23dc0d09b460ec8347d1056
ToppCellfacs-BAT-Fat-3m-Epithelial-epithelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASIC1 GRB7 ZNF579 AGBL3

4.94e-04177924128186bc996784e670194c07c5352e69af5f6d68
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF142 INSM1 GAN RAD54L2

4.94e-04177924e1e45956887371b1c18f1eb479dd930031497520
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CIITA INSM1 MAP3K14 UVRAG

4.94e-04177924d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CIITA INSM1 MAP3K14 UVRAG

4.94e-0417792470ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCellNS-moderate-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MXD3 TYMSOS CEP152 CCDC85A

4.94e-04177924174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CIITA MAP3K14 CBFA2T3 ST18

4.94e-04177924c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellfacs-BAT-Fat-3m-Epithelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASIC1 GRB7 ZNF579 AGBL3

4.94e-041779247480e522cfae3f5c6c62720083750f8273725ab5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 CIITA CBFA2T3 KLHDC10

5.05e-04178924ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 CIITA CBFA2T3 KLHDC10

5.05e-041789246c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
Disease5,6-dihydrothymine measurement

ZNF845 CIITA

3.19e-049892EFO_0800638
Diseasetrypsin-3 measurement

ZNF799 CBFA2T3

4.86e-0411892EFO_0020791
Diseaseulcerative colitis

CIITA GRB7 NFKBIZ ZNF831 KIR3DL2 ZNF365

5.40e-04335896EFO_0000729
Diseasebody weights and measures, body height

ADAMTS10 MXD3

9.21e-0415892EFO_0004324, EFO_0004339
Diseaseproprotein convertase subtilisin/kexin type 7 measurement

RNF214 PCSK7

1.19e-0317892EFO_0008270
Diseaselysophosphatidylcholine 18:1 measurement

ST18 CCDC85A

1.19e-0317892EFO_0010360
Diseaseresponse to radiation, Hematuria

CCDC85A CACNA2D3

2.18e-0323892GO_0009314, HP_0000790
Diseasestomach carcinoma (is_marker_for)

GRB7 TNFAIP3

2.38e-0324892DOID:5517 (is_marker_for)
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

RNF214 OR4A15 EEPD1 PCSK7 UVRAG

2.68e-03315895EFO_0004612, EFO_0008591
Diseasecolorectal cancer, breast carcinoma

ZNF808 ZNF578

2.79e-0326892EFO_0000305, MONDO_0005575
Diseaselysophosphatidylcholine 18:2 measurement

ZNF365 CCDC85A

3.23e-0328892EFO_0010361

Protein segments in the cluster

PeptideGeneStartEntry
CKLRLPGSRHSPASA

AGBL3

706

Q8NEM8
QEKCLPSSRHRGPRS

CARD10

776

Q9BWT7
CGHPSRHKADRLKSD

CEP152

1656

O94986
RPLLLSHSHSPTLCR

CIITA

601

P33076
HPLCARLVEKPSRGS

ASB10

21

Q8WXI3
SLKEGRPHHPRAKCT

CEP72

166

Q9P209
PCGDRHPVLDLRGHK

RAD54L2

1241

Q9Y4B4
HKCRSLRASESGHLP

ANO9

501

A1A5B4
GCHRSIPRDPSDLSH

EEPD1

6

Q7L9B9
KRSSLRHPHLDTACG

ADAMTS10

181

Q9H324
VSHRSRLCTNPKPSH

ADAMTS16

606

Q8TE57
RPPLHLLRSGTFACK

ARHGEF39

261

Q8N4T4
PLRVSRGKTNHPLHC

CHDH

186

Q8NE62
HRHHSQRSKCRPPKG

RCOR3

206

Q9P2K3
DSCHRVKSPHRSPGS

IQCC

246

Q4KMZ1
PTEPSSKSGICRHLH

KIR3DL2

326

P43630
RGSSLHLHVSKPPRE

NCLN

316

Q969V3
VKRCDERHGRPLPHS

LINC02906

36

E5RJ46
DSRPCRHLPKTISFH

FBLN7

326

Q53RD9
KPRCGVPDHPHLSRR

MMP24

136

Q9Y5R2
ICSHRLDPKSPGLNR

MUC16

12926

Q8WXI7
ICTHHPDPKSPRLDR

MUC16

13706

Q8WXI7
RCLTEHSGPKHTQHP

DNAJC14

51

Q6Y2X3
VKETPLPARRSHHCV

KLHL36

326

Q8N4N3
PKAALHRHGRLSPRS

LEFTY1

126

O75610
LSDGPACKRPALLHS

NFKBIZ

171

Q9BYH8
SLCPHRSPGPIHRRK

MXD3

31

Q9BW11
SHDRVGRLSPCVPAK

NAB2

471

Q15742
CSEHRPKIKSEHPGL

HMGB2

106

P26583
SARRHHLGPTLKPTL

MBD1

411

Q9UIS9
HPRRGSLELKLFCPS

PCSK7

536

Q16549
PHEKIGFPAARRCHS

KLHDC10

306

Q6PID8
VCRLRHLSPTPSEEH

OR4A15

16

Q8NGL6
HRASDLHELSAPCRP

METRNL

176

Q641Q3
SKAERAGPPLSSLHH

PRSS54

266

Q6PEW0
RDPLHPEHLSKRPCT

CBFA2T3

306

O75081
SRHLHPSCLGSPPLR

GRB7

351

Q14451
SHGLRLAAPCRKHEP

PTK6

161

Q13882
PHSTRCRKEDAQPGH

CRNKL1

86

Q9BZJ0
QKIRRRPESCHGFHP

CACNA2D3

1046

Q8IZS8
PTCHRLSAAERVTHP

DYTN

211

A2CJ06
HTKPLLPSDLRRTGC

GAN

556

Q9H2C0
HSPLTPHRRDLCSRS

CNTF

6

P26441
HRSASPEHPQKPRAC

CCDC85A

251

Q96PX6
PKAALHRHGRLSPRS

LEFTY2

126

O00292
ASHCRDLLPHPVLGR

HOXC13

66

P31276
RSPCSPSHHKRSRFG

MARCHF10

306

Q8NA82
HPGSPKDHERNGCRL

GEN1

266

Q17RS7
RLLTRAHAECPPAHT

CRIPAK

126

Q8N1N5
RASLARCPKTNHRGP

ETV2

226

O00321
LSRSCLAKGSPERHH

PPP1R18

521

Q6NYC8
KRKTRHSTNPPLECH

LARP1B

636

Q659C4
KVLGHPCTRTPHFLR

PTPRM

176

P28827
TPLHLTTRHRSPKCL

INVS

116

Q9Y283
SPGLTRHINKCHPSE

INSM1

481

Q01101
PHLEPSCLSRGAHEK

MAP3K14

316

Q99558
CDRHHTSSAIPVPKR

UVRAG

466

Q9P2Y5
DRPGHSHLCPSVRAT

RGL2

276

O15211
RSASPHCLKNIHSLP

TIGD6

231

Q17RP2
NLPTHPHCSRLRLAD

TEX14

276

Q8IWB6
SAPPRKDVPHRCSTH

MMP17

321

Q9ULZ9
RTCPHLRQPKHGHIS

SVEP1

436

Q4LDE5
KRTASRSPASCHEHP

OSBPL10

501

Q9BXB5
HTELACRKAPDGHPL

STARD8

846

Q92502
HSSPRPASAKHCRKL

STK36

1291

Q9NRP7
HRSLSGCPHKVRVPL

ST18

386

O60284
VKRHNPCESLRGHPA

ASIC1

491

P78348
SSLTRHCRLHTGEKP

ZNF845

536

Q96IR2
STLTCHRRLHTGEKP

ZNF525

396

Q8N782
ESLHPVTRSLKAGCH

RNF214

126

Q8ND24
LLGHLKRFDHSPCDP

ZNF451

186

Q9Y4E5
KRFDHSPCDPTITLH

ZNF451

191

Q9Y4E5
KIHETAARPPAVCSH

ZNF718

66

Q3SXZ3
SLIRHRRCHKDVPPA

ZNF865

266

P0CJ78
KHIRTHTGERPFKCP

ZNF143

316

P52747
SSLPCHRRLHSGEKP

ZNF578

496

Q96N58
RKPKCLSRGHPHSVC

ZNF365

316

Q70YC5
HPSRRGPRRHLSGCS

TYMSOS

91

Q8TAI1
DPSRLVRSPSPHSCH

TNFAIP3

566

P21580
ACRIHHPSLPASGRS

TAPBP

381

O15533
RPAKCSTPARHNSIH

THSD1

441

Q9NS62
IRHSPSKCRLHPSES

SOGA1

1396

O94964
SSCLRHERTHTGKKP

ZNF799

266

Q96GE5
SSLLCHRRLHSGEKP

ZNF808

496

Q8N4W9
DHAPHTLEEKCGSRP

CAD

1686

P27708
DGPALKRCRTVSPAH

ZMIZ2

696

Q8NF64
LVHHRSCKPKGEGPR

ZNF474

181

Q6S9Z5
RHQRTHLGAKPFRCP

ZNF648

381

Q5T619
HRLRVHDKTPTHFCP

ZNF142

1246

P52746
LCPSPASLRGHTRKQ

ZNF142

1336

P52746
HPRLSGVPITCLARH

VSIG10L

551

Q86VR7
KHIRSHTGERPFPCA

ZNF831

161

Q5JPB2
SRAPCLLKHERLHSG

ZNF224

466

Q9NZL3
RHQRTHTGERPFKCP

ZNF777

711

Q9ULD5
LCPKAFRRPAHLSRH

ZNF579

76

Q8NAF0
LSKAPHRGRPSLCAH

ZNF764

151

Q96H86
PGASTQPLCRKHALR

LRRC14

101

Q15048