Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MEGF9 LAMA3 LAMC1 SRPX SSPOP	3.41e-04	188	64	5	GO:0005201
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF823 ZNF765 ZC3H8 ZNF549 ZBTB21 NFXL1 ZNF616 ZNF112 ZHX2 CASZ1 NOTCH1 ZFY ZNF639	4.60e-04	1412	64	13	GO:0000981
GeneOntologyMolecularFunction	molecular function activator activity	JAG2 GARNL3 EGF PIK3CA RABGAP1L FSHB NRG2 RABGAP1 NOTCH1 AGAP1 AGAP3 SEMA4C	4.80e-04	1233	64	12	GO:0140677
GeneOntologyMolecularFunction	poly(A)-specific ribonuclease activity	CNOT6 CNOT6L	7.71e-04	13	64	2	GO:0004535
GeneOntologyBiologicalProcess	retina morphogenesis in camera-type eye	CFH ZHX2 CASZ1 NOTCH1 RHO	9.50e-06	90	65	5	GO:0060042
GeneOntologyBiologicalProcess	retinal bipolar neuron differentiation	ZHX2 CASZ1 RHO	1.32e-05	15	65	3	GO:0060040
GeneOntologyBiologicalProcess	camera-type eye morphogenesis	CFH ADAMTS9 ZHX2 CASZ1 NOTCH1 RHO	1.64e-05	171	65	6	GO:0048593
GeneOntologyBiologicalProcess	neural retina development	CFH ZHX2 CASZ1 NOTCH1 RHO	1.75e-05	102	65	5	GO:0003407
GeneOntologyBiologicalProcess	eye morphogenesis	CFH ADAMTS9 ZHX2 CASZ1 NOTCH1 RHO	4.42e-05	204	65	6	GO:0048592
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	CFH PASK CLSTN3 FMO1 PIK3CA ZC3H8 FSHB LAMC1 MLLT6 NOTCH1 ZFY RHO	8.82e-05	1043	65	12	GO:0048871
GeneOntologyBiologicalProcess	glutamatergic neuron differentiation	ZHX2 CASZ1 RHO	1.03e-04	29	65	3	GO:1905962
GeneOntologyBiologicalProcess	animal organ morphogenesis	JAG2 CFH PAPPA2 MEGF9 ADAMTS9 NGFR LAMA3 LAMC1 ZHX2 CASZ1 NOTCH1 ALPK2 RHO	1.39e-04	1269	65	13	GO:0009887
GeneOntologyBiologicalProcess	inner ear receptor cell fate commitment	JAG2 NOTCH1	1.45e-04	6	65	2	GO:0060120
GeneOntologyBiologicalProcess	hemidesmosome assembly	LAMA3 LAMC1	1.45e-04	6	65	2	GO:0031581
GeneOntologyBiologicalProcess	auditory receptor cell fate commitment	JAG2 NOTCH1	1.45e-04	6	65	2	GO:0009912
GeneOntologyBiologicalProcess	positive regulation of cytoplasmic mRNA processing body assembly	CNOT6 CNOT6L	1.45e-04	6	65	2	GO:0010606
GeneOntologyBiologicalProcess	negative regulation of photoreceptor cell differentiation	CASZ1 NOTCH1	2.03e-04	7	65	2	GO:0046533
GeneOntologyBiologicalProcess	negative regulation of neuron differentiation	ZHX2 TTC3 CASZ1 NOTCH1	2.21e-04	94	65	4	GO:0045665
GeneOntologyBiologicalProcess	regulation of cytoplasmic mRNA processing body assembly	CNOT6 CNOT6L	2.70e-04	8	65	2	GO:0010603
GeneOntologyBiologicalProcess	regulation of photoreceptor cell differentiation	CASZ1 NOTCH1	2.70e-04	8	65	2	GO:0046532
GeneOntologyBiologicalProcess	hair follicle morphogenesis	NGFR LAMC1 NOTCH1	2.72e-04	40	65	3	GO:0031069
GeneOntologyBiologicalProcess	axon guidance	MEGF9 NGFR LAMA3 LAMC1 NOTCH1 SEMA4C	2.75e-04	285	65	6	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	MEGF9 NGFR LAMA3 LAMC1 NOTCH1 SEMA4C	2.81e-04	286	65	6	GO:0097485
GeneOntologyBiologicalProcess	cell surface receptor signaling pathway involved in heart development	NOTCH1 ALPK2	3.47e-04	9	65	2	GO:0061311
GeneOntologyBiologicalProcess	axonogenesis	MEGF9 CNTNAP1 NGFR LAMA3 LAMC1 TTC3 NOTCH1 SEMA4C	3.90e-04	566	65	8	GO:0007409
GeneOntologyBiologicalProcess	epidermis morphogenesis	NGFR LAMC1 NOTCH1	4.12e-04	46	65	3	GO:0048730
GeneOntologyBiologicalProcess	diacylglycerol biosynthetic process	PLPP1 AVIL	4.33e-04	10	65	2	GO:0006651
GeneOntologyBiologicalProcess	camera-type eye photoreceptor cell differentiation	CFH CASZ1 NOTCH1	4.96e-04	49	65	3	GO:0060219
GeneOntologyBiologicalProcess	retina development in camera-type eye	CFH ZHX2 CASZ1 NOTCH1 RHO	5.36e-04	211	65	5	GO:0060041
GeneOntologyCellularComponent	extracellular matrix	MEGF9 ADAMTS9 LAMA3 LAMC1 MUC5B SRPX SSPOP SVEP1 EGFL6	1.65e-04	656	64	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MEGF9 ADAMTS9 LAMA3 LAMC1 MUC5B SRPX SSPOP SVEP1 EGFL6	1.69e-04	658	64	9	GO:0030312
GeneOntologyCellularComponent	laminin complex	LAMA3 LAMC1	4.09e-04	10	64	2	GO:0043256
GeneOntologyCellularComponent	basement membrane	MEGF9 LAMA3 LAMC1 EGFL6	5.35e-04	122	64	4	GO:0005604
GeneOntologyCellularComponent	CCR4-NOT complex	CNOT6 CNOT6L	1.08e-03	16	64	2	GO:0030014
GeneOntologyCellularComponent	collagen-containing extracellular matrix	MEGF9 ADAMTS9 LAMA3 LAMC1 SRPX SSPOP EGFL6	1.15e-03	530	64	7	GO:0062023
Domain	EGF_1	JAG2 EGF MEGF9 CNTNAP1 LAMA3 NRG2 LAMC1 LRP1B SSPOP SVEP1 NOTCH1 EGFL6	6.87e-11	255	65	12	PS00022
Domain	EGF_2	JAG2 EGF MEGF9 CNTNAP1 LAMA3 NRG2 LAMC1 LRP1B SSPOP SVEP1 NOTCH1 EGFL6	1.07e-10	265	65	12	PS01186
Domain	EGF	JAG2 EGF MEGF9 CNTNAP1 LAMA3 NRG2 LAMC1 LRP1B SVEP1 NOTCH1 EGFL6	4.88e-10	235	65	11	SM00181
Domain	EGF-like_dom	JAG2 EGF MEGF9 CNTNAP1 LAMA3 NRG2 LAMC1 LRP1B SVEP1 NOTCH1 EGFL6	9.00e-10	249	65	11	IPR000742
Domain	EGF-like_CS	JAG2 EGF MEGF9 CNTNAP1 LAMA3 NRG2 LAMC1 LRP1B SVEP1 NOTCH1 EGFL6	1.48e-09	261	65	11	IPR013032
Domain	Growth_fac_rcpt_	JAG2 EGF LAMA3 LAMC1 LRP1B SVEP1 NOTCH1 EGFL6	6.67e-08	156	65	8	IPR009030
Domain	EGF_3	JAG2 EGF CNTNAP1 NRG2 LRP1B SSPOP SVEP1 NOTCH1 EGFL6	1.18e-07	235	65	9	PS50026
Domain	EGF	JAG2 EGF CNTNAP1 NRG2 LRP1B SVEP1 NOTCH1	2.71e-07	126	65	7	PF00008
Domain	EGF_CA	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	5.31e-07	86	65	6	PF07645
Domain	EGF_Ca-bd_CS	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	1.08e-06	97	65	6	IPR018097
Domain	EGF_CA	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	1.22e-06	99	65	6	PS01187
Domain	ASX_HYDROXYL	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	1.30e-06	100	65	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	1.82e-06	106	65	6	IPR000152
Domain	EGF_CA	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	4.14e-06	122	65	6	SM00179
Domain	EGF-like_Ca-bd_dom	JAG2 EGF LRP1B SVEP1 NOTCH1 EGFL6	4.55e-06	124	65	6	IPR001881
Domain	-	EGF SVEP1 EGFL6	6.51e-06	11	65	3	2.40.155.10
Domain	GFP-like	EGF SVEP1 EGFL6	6.51e-06	11	65	3	IPR023413
Domain	-	PAPPA2 CLSTN3 CNTNAP1 LAMA3 SVEP1	1.99e-05	95	65	5	2.60.120.200
Domain	zf-C2H2	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	2.44e-05	693	65	11	PF00096
Domain	Sushi	CFH PAPPA2 SRPX SVEP1	3.19e-05	52	65	4	PF00084
Domain	HYR	SRPX SVEP1	3.57e-05	3	65	2	PS50825
Domain	HYR	SRPX SVEP1	3.57e-05	3	65	2	PF02494
Domain	HYR_dom	SRPX SVEP1	3.57e-05	3	65	2	IPR003410
Domain	CCP	CFH PAPPA2 SRPX SVEP1	3.71e-05	54	65	4	SM00032
Domain	VWC_out	JAG2 MUC5B SSPOP	3.75e-05	19	65	3	SM00215
Domain	SUSHI	CFH PAPPA2 SRPX SVEP1	4.28e-05	56	65	4	PS50923
Domain	Sushi_SCR_CCP_dom	CFH PAPPA2 SRPX SVEP1	4.59e-05	57	65	4	IPR000436
Domain	EGF_extracell	JAG2 LRP1B SVEP1 NOTCH1	5.63e-05	60	65	4	IPR013111
Domain	EGF_2	JAG2 LRP1B SVEP1 NOTCH1	5.63e-05	60	65	4	PF07974
Domain	ZINC_FINGER_C2H2_2	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	6.75e-05	775	65	11	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	6.91e-05	777	65	11	PS00028
Domain	Znf_C2H2-like	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	8.57e-05	796	65	11	IPR015880
Domain	Znf_C2H2	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	9.48e-05	805	65	11	IPR007087
Domain	ZnF_C2H2	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	9.79e-05	808	65	11	SM00355
Domain	ConA-like_dom	PAPPA2 CLSTN3 CNTNAP1 LAMA3 SVEP1 EGFL6	1.13e-04	219	65	6	IPR013320
Domain	hEGF	JAG2 SVEP1 NOTCH1	1.24e-04	28	65	3	PF12661
Domain	EGF_LAM_2	MEGF9 LAMA3 LAMC1	1.53e-04	30	65	3	PS50027
Domain	EGF_LAM_1	MEGF9 LAMA3 LAMC1	1.53e-04	30	65	3	PS01248
Domain	DUF3694	RABGAP1L RABGAP1	1.77e-04	6	65	2	PF12473
Domain	Kinesin-like	RABGAP1L RABGAP1	1.77e-04	6	65	2	IPR022164
Domain	Laminin_EGF	MEGF9 LAMA3 LAMC1	2.43e-04	35	65	3	PF00053
Domain	EGF_Lam	MEGF9 LAMA3 LAMC1	2.43e-04	35	65	3	SM00180
Domain	Notch_dom	PAPPA2 NOTCH1	2.48e-04	7	65	2	IPR000800
Domain	Notch	PAPPA2 NOTCH1	2.48e-04	7	65	2	PF00066
Domain	NL	PAPPA2 NOTCH1	2.48e-04	7	65	2	SM00004
Domain	VWFC_1	JAG2 MUC5B SSPOP	2.65e-04	36	65	3	PS01208
Domain	VWC	JAG2 MUC5B SSPOP	3.11e-04	38	65	3	SM00214
Domain	VWFC_2	JAG2 MUC5B SSPOP	3.11e-04	38	65	3	PS50184
Domain	Laminin_EGF	MEGF9 LAMA3 LAMC1	3.11e-04	38	65	3	IPR002049
Domain	LAMININ_IVA	LAMA3 LAMC1	3.29e-04	8	65	2	PS51115
Domain	Laminin_B	LAMA3 LAMC1	3.29e-04	8	65	2	PF00052
Domain	LamB	LAMA3 LAMC1	3.29e-04	8	65	2	SM00281
Domain	Laminin_IV	LAMA3 LAMC1	3.29e-04	8	65	2	IPR000034
Domain	VWF_dom	JAG2 MUC5B SSPOP	4.19e-04	42	65	3	IPR001007
Domain	-	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZFY ZNF639	5.45e-04	679	65	9	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZFY ZNF639	6.37e-04	694	65	9	IPR013087
Domain	TIL	MUC5B SSPOP	7.70e-04	12	65	2	PF01826
Domain	C8	MUC5B SSPOP	7.70e-04	12	65	2	PF08742
Domain	Roc	AGAP1 AGAP3	9.08e-04	13	65	2	PF08477
Domain	MIRO-like	AGAP1 AGAP3	9.08e-04	13	65	2	IPR013684
Domain	Unchr_dom_Cys-rich	MUC5B SSPOP	9.08e-04	13	65	2	IPR014853
Domain	C8	MUC5B SSPOP	9.08e-04	13	65	2	SM00832
Domain	TIL_dom	MUC5B SSPOP	1.06e-03	14	65	2	IPR002919
Domain	Ldl_recept_b	EGF LRP1B	1.06e-03	14	65	2	PF00058
Domain	LDLRB	EGF LRP1B	1.06e-03	14	65	2	PS51120
Domain	Glyco_hormone_CN	FSHB MUC5B	1.22e-03	15	65	2	IPR006208
Domain	Cys_knot	FSHB MUC5B	1.22e-03	15	65	2	PF00007
Domain	LY	EGF LRP1B	1.22e-03	15	65	2	SM00135
Domain	LDLR_classB_rpt	EGF LRP1B	1.22e-03	15	65	2	IPR000033
Domain	VWD	MUC5B SSPOP	1.39e-03	16	65	2	SM00216
Domain	VWF_type-D	MUC5B SSPOP	1.39e-03	16	65	2	IPR001846
Domain	Laminin_N	LAMA3 LAMC1	1.39e-03	16	65	2	IPR008211
Domain	LAMININ_NTER	LAMA3 LAMC1	1.39e-03	16	65	2	PS51117
Domain	VWFD	MUC5B SSPOP	1.39e-03	16	65	2	PS51233
Domain	Laminin_N	LAMA3 LAMC1	1.39e-03	16	65	2	PF00055
Domain	VWD	MUC5B SSPOP	1.39e-03	16	65	2	PF00094
Domain	LamNT	LAMA3 LAMC1	1.39e-03	16	65	2	SM00136
Domain	KRAB	ZNF823 ZNF765 ZNF45 ZNF549 ZNF616 ZNF112	1.52e-03	358	65	6	PS50805
Domain	KRAB	ZNF823 ZNF765 ZNF45 ZNF549 ZNF616 ZNF112	1.52e-03	358	65	6	PF01352
Domain	CTCK_1	MUC5B SSPOP	1.76e-03	18	65	2	PS01185
Domain	KRAB	ZNF823 ZNF765 ZNF45 ZNF549 ZNF616 ZNF112	1.77e-03	369	65	6	SM00349
Domain	KRAB	ZNF823 ZNF765 ZNF45 ZNF549 ZNF616 ZNF112	1.79e-03	370	65	6	IPR001909
Domain	-	CNTNAP1 LAMC1 SSPOP	2.10e-03	73	65	3	2.60.120.260
Domain	FA58C	CNTNAP1 SSPOP	2.40e-03	21	65	2	SM00231
Domain	FA58C_3	CNTNAP1 SSPOP	2.40e-03	21	65	2	PS50022
Domain	FA58C_1	CNTNAP1 SSPOP	2.40e-03	21	65	2	PS01285
Domain	FA58C_2	CNTNAP1 SSPOP	2.40e-03	21	65	2	PS01286
Domain	MetalloPept_cat_dom	PAPPA2 ADAMTS9 MME	2.83e-03	81	65	3	IPR024079
Domain	-	PAPPA2 ADAMTS9 MME	2.83e-03	81	65	3	3.40.390.10
Domain	F5_F8_type_C	CNTNAP1 SSPOP	3.13e-03	24	65	2	PF00754
Domain	FA58C	CNTNAP1 SSPOP	3.13e-03	24	65	2	IPR000421
Domain	Cys_knot_C	MUC5B SSPOP	3.40e-03	25	65	2	IPR006207
Domain	CTCK_2	MUC5B SSPOP	3.40e-03	25	65	2	PS01225
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	EGF PIK3CA LAMA3 LAMC1	1.46e-05	46	46	4	M239
Pathway	REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	EGF PIK3CA NRG2	1.77e-05	16	46	3	M570
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS9 MUC5B SSPOP NOTCH1	6.94e-05	68	46	4	M27303
Pathway	REACTOME_SIGNALING_BY_ERBB2_IN_CANCER	EGF PIK3CA NRG2	8.02e-05	26	46	3	M29535
Pathway	REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT	JAG2 NOTCH1	2.16e-04	7	46	2	M27199
Pathway	REACTOME_SIGNALING_BY_NOTCH	JAG2 EGF NOTCH1	2.74e-04	39	46	3	MM14604
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGF PIK3CA	2.88e-04	8	46	2	M47498
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	EGF PIK3CA	3.70e-04	9	46	2	M47392
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	JAG2 NOTCH1	4.61e-04	10	46	2	MM14849
Pathway	REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING	PIK3CA NRG2	4.61e-04	10	46	2	M568
Pathway	REACTOME_SIGNALING_BY_NOTCH3	JAG2 EGF NOTCH1	5.39e-04	49	46	3	M618
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	EGF NOTCH1	5.62e-04	11	46	2	M48021
Pathway	PID_INTEGRIN4_PATHWAY	LAMA3 LAMC1	5.62e-04	11	46	2	M158
Pathway	KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	PIK3CA NRG2	5.62e-04	11	46	2	M47756
Pathway	REACTOME_SIGNALING_BY_ERBB2	EGF PIK3CA NRG2	5.72e-04	50	46	3	M553
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGF PIK3CA	6.73e-04	12	46	2	M47393
Pathway	REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING	EGF NRG2	7.94e-04	13	46	2	M27729
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	JAG2 NOTCH1	7.94e-04	13	46	2	M47423
Pathway	REACTOME_SIGNALING_BY_ERBB4	EGF PIK3CA NRG2	8.85e-04	58	46	3	M544
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	EGF PIK3CA	9.25e-04	14	46	2	M47536
Pathway	REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	EGF PIK3CA	9.25e-04	14	46	2	MM14761
Pathway	PID_NOTCH_PATHWAY	JAG2 SSPOP NOTCH1	9.30e-04	59	46	3	M17
Pathway	PID_ERBB_NETWORK_PATHWAY	EGF NRG2	1.06e-03	15	46	2	M201
Pathway	REACTOME_CONSTITUTIVE_SIGNALING_BY_EGFRVIII	EGF PIK3CA	1.06e-03	15	46	2	M29701
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	EGF PIK3CA	1.06e-03	15	46	2	M47389
Pathway	REACTOME_ERBB2_REGULATES_CELL_MOTILITY	EGF NRG2	1.06e-03	15	46	2	M27608
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	JAG2 NOTCH1	1.06e-03	15	46	2	M27202
Pathway	WP_CANCER_PATHWAYS	JAG2 EGF PIK3CA LAMA3 LAMC1 ADCY9 NOTCH1	1.18e-03	507	46	7	M48302
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS9 MUC5B SSPOP NOTCH1	1.19e-03	143	46	4	M27275
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	JAG2 NOTCH1	1.21e-03	16	46	2	M47424
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	FSHB ADCY9	1.21e-03	16	46	2	M47650
Pathway	REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING	EGF NRG2	1.21e-03	16	46	2	M562
Pathway	REACTOME_SIGNALING_BY_ERBB2_ECD_MUTANTS	EGF PIK3CA	1.21e-03	16	46	2	M29847
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	PIK3CA LAMA3 LAMC1	1.29e-03	66	46	3	MM15925
Pathway	WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION	JAG2 NOTCH1	1.37e-03	17	46	2	M39389
Pathway	REACTOME_GAB1_SIGNALOSOME	EGF PIK3CA	1.37e-03	17	46	2	MM14700
Pathway	PID_NFKAPPAB_ATYPICAL_PATHWAY	PIK3CA SSPOP	1.37e-03	17	46	2	M26
Pathway	SA_TRKA_RECEPTOR	PIK3CA NGFR	1.37e-03	17	46	2	M18895
Pathway	REACTOME_GAB1_SIGNALOSOME	EGF PIK3CA	1.37e-03	17	46	2	M10450
Pathway	REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS	PIK3CA ZMYM2	1.54e-03	18	46	2	M673
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	CNOT6 CNOT6L	1.54e-03	18	46	2	MM15336
Pathway	REACTOME_SIGNALING_BY_NOTCH1	JAG2 NOTCH1	1.54e-03	18	46	2	MM14775
Pathway	WP_BREAST_CANCER_PATHWAY	JAG2 EGF PIK3CA NOTCH1	1.56e-03	154	46	4	M39739
Pathway	REACTOME_SIGNALING_BY_NOTCH3	JAG2 EGF	1.72e-03	19	46	2	MM15594
Pathway	REACTOME_CONSTITUTIVE_SIGNALING_BY_LIGAND_RESPONSIVE_EGFR_CANCER_VARIANTS	EGF PIK3CA	1.72e-03	19	46	2	M559
Pathway	REACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS	PIK3CA ZMYM2	1.72e-03	19	46	2	M41732
Pathway	BIOCARTA_NGF_PATHWAY	PIK3CA NGFR	1.91e-03	20	46	2	M7860
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	CNOT6 CNOT6L	2.10e-03	21	46	2	M27634
Pathway	REACTOME_SIGNALING_BY_MET	PIK3CA LAMA3 LAMC1	2.16e-03	79	46	3	M27643
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	JAG2 PLPP1 ERV3-1 ZC3H8 PCNX4 LAMA3 L2HGDH RABGAP1 MME ZHX2 TTC3 SSPOP CASZ1 AGAP1 AGAP3	7.65e-08	1489	65	15	28611215
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	NFXL1 LAMC1 ZNF112 TTC3 SSPOP	2.31e-07	71	65	5	33541421
Pubmed	Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.	JAG2 NGFR NOTCH1	2.23e-06	14	65	3	28192800
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS9 LAMA3 LAMC1	3.43e-06	16	65	3	30579834
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	3.44e-06	2	65	2	34788619
Pubmed	[Expression and significance of Notch-1 and Jagged-2 in patients with Hirschsprung disease].	JAG2 NOTCH1	3.44e-06	2	65	2	22030773
Pubmed	Downregulation of Notch-1/Jagged-2 in human colon tissues from Hirschsprung disease patients.	JAG2 NOTCH1	3.44e-06	2	65	2	21892607
Pubmed	Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.	JAG2 NOTCH1	3.44e-06	2	65	2	23074278
Pubmed	NOTCH1 and PIK3CA mutation are related to HPV-associated vulvar squamous cell carcinoma.	PIK3CA NOTCH1	3.44e-06	2	65	2	37839360
Pubmed	The dermal-epidermal junction of human skin contains a novel laminin variant.	LAMA3 LAMC1	3.44e-06	2	65	2	1383241
Pubmed	Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.	JAG2 NOTCH1	3.44e-06	2	65	2	11700865
Pubmed	Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China.	PIK3CA NOTCH1	3.44e-06	2	65	2	26528858
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	3.44e-06	2	65	2	21233283
Pubmed	Epidermal growth factor regulates NIKS keratinocyte proliferation through Notch signaling.	EGF NOTCH1	3.44e-06	2	65	2	23899513
Pubmed	Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.	EGF NGFR MUC5B	9.35e-06	22	65	3	12768436
Pubmed	Immunohistochemical expression and prognostic role of CD10, CD271 and Nestin in primary and recurrent cutaneous melanoma.	NGFR MME	1.03e-05	3	65	2	30251808
Pubmed	Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling.	PIK3CA NOTCH1	1.03e-05	3	65	2	22463491
Pubmed	Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.	PIK3CA NOTCH1	1.03e-05	3	65	2	26880557
Pubmed	Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.	CNOT6 CNOT6L	1.03e-05	3	65	2	30926667
Pubmed	CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.	CNOT6 CNOT6L	1.03e-05	3	65	2	30478191
Pubmed	Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3.	NGFR NOTCH1	1.03e-05	3	65	2	16539652
Pubmed	Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells.	FSHB NOTCH1	1.03e-05	3	65	2	20613903
Pubmed	Downregulation of a newly identified laminin, laminin-3B11, in vascular basement membranes of invasive human breast cancers.	LAMA3 LAMC1	1.03e-05	3	65	2	21276136
Pubmed	Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.	ZMYM2 NOTCH1	1.03e-05	3	65	2	21527531
Pubmed	Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells.	NGFR NOTCH1	1.03e-05	3	65	2	17241776
Pubmed	Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse.	JAG2 NOTCH1	1.03e-05	3	65	2	19181188
Pubmed	Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition.	LAMA3 LAMC1	1.03e-05	3	65	2	9019243
Pubmed	ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.	JAG2 NOTCH1	1.03e-05	3	65	2	38485033
Pubmed	Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.	JAG2 NOTCH1	1.03e-05	3	65	2	18458347
Pubmed	Absence of the frequently reported PIK3CA, CASP8, and NOTCH1 mutations in South Indian oral cancers.	PIK3CA NOTCH1	1.03e-05	3	65	2	28181739
Pubmed	The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.	JAG2 NOTCH1	1.03e-05	3	65	2	37330998
Pubmed	Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.	JAG2 NGFR NOTCH1	1.07e-05	23	65	3	23386589
Pubmed	Rbpj regulates development of prosensory cells in the mammalian inner ear.	JAG2 NGFR NOTCH1	1.23e-05	24	65	3	21420948
Pubmed	Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1.	CFH EGF LAMC1	1.76e-05	27	65	3	2574151
Pubmed	A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.	JAG2 NOTCH1	2.06e-05	4	65	2	10837254
Pubmed	Notch signalling pathway mediates hair cell development in mammalian cochlea.	JAG2 NOTCH1	2.06e-05	4	65	2	10080181
Pubmed	Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis.	LAMC1 EGFL6	2.06e-05	4	65	2	15572035
Pubmed	TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling.	EGF PIK3CA	2.06e-05	4	65	2	24769208
Pubmed	The Notch signalling pathway in hair growth.	JAG2 NOTCH1	2.06e-05	4	65	2	9858728
Pubmed	Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.	CNOT6 CNOT6L	2.06e-05	4	65	2	35385705
Pubmed	Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.	JAG2 NOTCH1	2.06e-05	4	65	2	24398584
Pubmed	The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells.	PIK3CA NOTCH1	2.06e-05	4	65	2	14583609
Pubmed	Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.	JAG2 NOTCH1	2.06e-05	4	65	2	9315665
Pubmed	Activation of Notch signaling in human tongue carcinoma.	JAG2 NOTCH1	2.06e-05	4	65	2	20819128
Pubmed	ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells.	EGF PIK3CA	2.06e-05	4	65	2	18990689
Pubmed	MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system.	MEGF9 LAMC1	2.06e-05	4	65	2	16981854
Pubmed	Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.	PIK3CA NOTCH1	2.06e-05	4	65	2	26670666
Pubmed	Different downstream pathways for Notch signaling are required for gliogenic and chondrogenic specification of mouse mesencephalic neural crest cells.	NGFR NOTCH1	2.06e-05	4	65	2	18299190
Pubmed	Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.	JAG2 NOTCH1	2.06e-05	4	65	2	20040020
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	LAMA3 LAMC1 EGFL6	2.20e-05	29	65	3	22613833
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NPC1 CFH CLSTN3 MEGF9 ADAMTS9 CNTNAP1 ZMYM2 TTC3 LRP1B AGAP1 AGAP3	2.41e-05	1285	65	11	35914814
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA3 LAMC1	3.43e-05	5	65	2	11969289
Pubmed	Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform.	JAG2 NOTCH1	3.43e-05	5	65	2	17332426
Pubmed	Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.	JAG2 NOTCH1	3.43e-05	5	65	2	12175503
Pubmed	EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR.	NGFR CASZ1	3.43e-05	5	65	2	22068036
Pubmed	Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.	JAG2 NOTCH1	3.43e-05	5	65	2	11006133
Pubmed	Rat pineal gland phosducin: cDNA isolation, nucleotide sequence, and chromosomal assignment in the mouse.	CFH LAMC1	3.43e-05	5	65	2	2071146
Pubmed	Functional diversity of notch family genes in fetal lung development.	JAG2 NOTCH1	3.43e-05	5	65	2	15064243
Pubmed	The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.	CNOT6 CNOT6L	3.43e-05	5	65	2	22977175
Pubmed	Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.	JAG2 NOTCH1	3.43e-05	5	65	2	32255245
Pubmed	Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.	CNOT6 CNOT6L	3.43e-05	5	65	2	35390160
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	PAPPA2 EGF LAMA3 LAMC1	3.52e-05	98	65	4	19834535
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 JAG2 PCNX4 DUSP5 MLLT6 TTC3 CASZ1 ADCY9 NOTCH1 AGAP3	3.69e-05	1105	65	10	35748872
Pubmed	The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.	JAG2 NOTCH1 RHO	3.91e-05	35	65	3	28402857
Pubmed	Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.	SYTL5 NOTCH1 SYCN	3.91e-05	35	65	3	30590051
Pubmed	Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.	JAG2 NOTCH1	5.13e-05	6	65	2	10958687
Pubmed	Expression and localization of laminin-5 subunits in the mouse incisor.	LAMA3 LAMC1	5.13e-05	6	65	2	9506922
Pubmed	Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.	CNOT6 CNOT6L	5.13e-05	6	65	2	31924127
Pubmed	A Role for phosphoinositide 3-kinase in the control of cell division and survival during retinal development.	PIK3CA RHO	5.13e-05	6	65	2	12086468
Pubmed	A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling.	EGF PIK3CA	5.13e-05	6	65	2	10648629
Pubmed	Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling.	EGF NOTCH1	5.13e-05	6	65	2	15156153
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	JAG2 MUC5B NOTCH1	6.31e-05	41	65	3	22675208
Pubmed	Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.	JAG2 NOTCH1	7.18e-05	7	65	2	10383933
Pubmed	Human ligands of the Notch receptor.	JAG2 NOTCH1	7.18e-05	7	65	2	10079256
Pubmed	The distribution of Notch receptors and their ligands during articular cartilage development.	JAG2 NOTCH1	7.18e-05	7	65	2	12846471
Pubmed	Evidence for a Notch1-mediated transition during olfactory ensheathing cell development.	JAG2 NOTCH1	7.18e-05	7	65	2	27271278
Pubmed	Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice.	JAG2 NOTCH1	7.18e-05	7	65	2	9531541
Pubmed	A new nomenclature for the laminins.	LAMA3 LAMC1	7.18e-05	7	65	2	7921537
Pubmed	Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.	JAG2 NOTCH1	7.18e-05	7	65	2	16169548
Pubmed	The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.	JAG2 NOTCH1	9.56e-05	8	65	2	16141228
Pubmed	Expression and localization of laminin-5 subunits during mouse tooth development.	LAMA3 LAMC1	9.56e-05	8	65	2	9489770
Pubmed	P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.	JAG2 NOTCH1	9.56e-05	8	65	2	22652674
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA3 LAMC1	9.56e-05	8	65	2	8872465
Pubmed	Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.	LAMA3 LAMC1	9.56e-05	8	65	2	23529140
Pubmed	Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.	JAG2 NOTCH1	9.56e-05	8	65	2	9858718
Pubmed	Notch/Delta expression in the developing mouse lung.	JAG2 NOTCH1	9.56e-05	8	65	2	11044610
Pubmed	Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors.	EGF NOTCH1	9.56e-05	8	65	2	15509736
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA3 LAMC1	9.56e-05	8	65	2	9852162
Pubmed	Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.	CFH LAMC1	9.56e-05	8	65	2	2993224
Pubmed	Math1 regulates development of the sensory epithelium in the mammalian cochlea.	NGFR NOTCH1	9.56e-05	8	65	2	15543141
Pubmed	Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.	CNOT6 CNOT6L	1.23e-04	9	65	2	21078877
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP1 AGAP3	1.23e-04	9	65	2	12640130
Pubmed	Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.	CNOT6 CNOT6L	1.23e-04	9	65	2	21741365
Pubmed	Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.	JAG2 NOTCH1	1.23e-04	9	65	2	11944948
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	JAG2 NOTCH1	1.23e-04	9	65	2	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	JAG2 NOTCH1	1.23e-04	9	65	2	16245338
Pubmed	Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.	ADAMTS9 NOTCH1	1.23e-04	9	65	2	23095891
Pubmed	NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch.	NGFR NOTCH1	1.23e-04	9	65	2	15496460
Pubmed	Notch signaling is essential for vascular morphogenesis in mice.	JAG2 NOTCH1	1.23e-04	9	65	2	10837027
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	JAG2 MLLT6 ZHX2 SSPOP NOTCH1 ZNF639 BEGAIN	1.40e-04	608	65	7	16713569
Interaction	IGFL3 interactions	JAG2 CNTNAP1 LAMA3 LRP1B NOTCH1	4.33e-06	75	65	5	int:IGFL3
Cytoband	Ensembl 112 genes in cytogenetic band chr9q33	GARNL3 MEGF9 RABGAP1	1.01e-03	138	65	3	chr9q33
Cytoband	Xp21.1	SYTL5 SRPX	1.08e-03	34	65	2	Xp21.1
Cytoband	19q13.2	ZNF45 ZNF112 SYCN	1.66e-03	164	65	3	19q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1q25	PAPPA2 RABGAP1L LAMC1	1.75e-03	167	65	3	chr1q25
Cytoband	18q11.2	NPC1 LAMA3	2.05e-03	47	65	2	18q11.2
Cytoband	17q21	CNTNAP1 MLLT6	3.65e-03	63	65	2	17q21
Cytoband	7q36.1	SSPOP AGAP3	4.99e-03	74	65	2	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr18q11	NPC1 LAMA3	6.53e-03	85	65	2	chr18q11
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF765 ZNF45 ZNF549 ZNF616 ZNF112 SYCN	6.80e-03	1192	65	6	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF823 ZNF765 ZNF45 ZNF549 ZBTB21 ZNF616 ZNF112 ZHX2 CASZ1 ZFY ZNF639	1.69e-06	718	47	11	28
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH PAPPA2 SRPX SVEP1	1.43e-05	57	47	4	1179
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L	3.58e-04	11	47	2	1023
GeneFamily	Laminin subunits	LAMA3 LAMC1	4.29e-04	12	47	2	626
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP3	8.77e-04	17	47	2	1291
GeneFamily	ArfGAPs	AGAP1 AGAP3	3.32e-03	33	47	2	395
Coexpression	NABA_MATRISOME	PAPPA2 EGF MEGF9 ADAMTS9 LAMA3 NRG2 LAMC1 MUC5B SRPX SSPOP SVEP1 EGFL6 SEMA4C	9.56e-07	1008	65	13	MM17056
Coexpression	NABA_MATRISOME	PAPPA2 EGF MEGF9 ADAMTS9 LAMA3 NRG2 LAMC1 MUC5B SRPX SSPOP SVEP1 EGFL6 SEMA4C	1.16e-06	1026	65	13	M5889
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	JAG2 CNOT6L MEGF9 ZC3H8 RABGAP1L LAMA3 GRM4 TTC3 LRP1B SSPOP CHRNA4 CASZ1 AGAP1	2.67e-06	1106	65	13	M39071
Coexpression	GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_DN	RABGAP1L DUSP5 NRG2 ZHX2 CASZ1 SEMA4C	9.00e-06	195	65	6	M9804
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	MEGF9 RABGAP1L ZHX2 ADGRL2 ADCY9	3.06e-05	145	65	5	M1810
Coexpression	HOSHIDA_LIVER_CANCER_SURVIVAL_UP	FMO1 EGF DUSP5 FSHB	3.30e-05	73	65	4	M6939
Coexpression	GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP	EGF ADAMTS9 DUSP5 NGFR SEMA4C	3.48e-05	149	65	5	M8786
Coexpression	BOQUEST_STEM_CELL_UP	CFH FMO1 SRPX MME LRP1B SVEP1	4.65e-05	261	65	6	M1834
Coexpression	COATES_MACROPHAGE_M1_VS_M2_UP	CFH LAMA3 ZNF616 TTC3	6.57e-05	87	65	4	M13671
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA3 LAMC1 SRPX SSPOP SVEP1	1.13e-04	191	65	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA3 LAMC1 SRPX SSPOP SVEP1	1.28e-04	196	65	5	M3008
Coexpression	GSE24814_STAT5_KO_VS_WT_PRE_BCELL_UP	CFH FMO1 LAMA3 LAMC1 ADGRL2	1.31e-04	197	65	5	M8426
Coexpression	GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP	JAG2 PLPP1 MEGF9 TTC3 AGAP1	1.34e-04	198	65	5	M9571
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP	CFH LAMC1 ZNF112 NOTCH1 AGAP1	1.34e-04	198	65	5	M3436
Coexpression	GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN	ZNF45 RABGAP1L RABGAP1 ZHX2 TTC3	1.37e-04	199	65	5	M4620
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	EGF RABGAP1L ADGRL2 LRP1B AGAP1	1.68e-04	208	65	5	M39233
Coexpression	LIM_MAMMARY_STEM_CELL_UP	PLPP1 NGFR LAMA3 LAMC1 SRPX MME SVEP1	1.82e-04	479	65	7	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	PLPP1 NGFR LAMA3 LAMC1 SRPX MME SVEP1	1.91e-04	483	65	7	MM1082
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_200	CFH ADAMTS9 ZNF616	3.34e-05	21	64	3	gudmap_developingGonad_e14.5_ epididymis_200_k2
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	CFH FMO1 PLPP1 ADAMTS9 LAMC1 SRPX MME SVEP1	5.53e-05	445	64	8	GSM777043_500
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	CFH PLPP1 LAMC1 SRPX MME ADGRL2 SVEP1 SEMA4C	6.47e-05	455	64	8	GSM777055_500
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	CFH FMO1 PLPP1 LAMC1 SRPX MME ADGRL2 SVEP1	7.64e-05	466	64	8	GSM777050_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	CNOT6 CFH CNOT6L MEGF9 ADAMTS9 ZNF616 SRPX SVEP1 EGFL6 AGAP1	1.18e-04	790	64	10	gudmap_developingGonad_e16.5_epididymis_1000
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH CLSTN3 NGFR LAMA3 ZHX2 ALPK2 EGFL6	1.40e-08	194	65	7	c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAG2 FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	3.41e-07	189	65	6	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAG2 FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	3.41e-07	189	65	6	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLSTN3 NGFR LAMA3 SRPX ALPK2 EGFL6	3.86e-07	193	65	6	c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLSTN3 NGFR LAMA3 SRPX ALPK2 EGFL6	4.35e-07	197	65	6	5fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JAG2 CFH NGFR LAMA3 NRG2	4.99e-06	170	65	5	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JAG2 CFH NGFR LAMA3 NRG2	4.99e-06	170	65	5	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	5.75e-06	175	65	5	eedb33e3e350169d1d37f2ac9939dcf704e7b696
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	PAPPA2 EGF ADGRL2 LRP1B CASZ1	8.14e-06	188	65	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 EGF ADGRL2 LRP1B CASZ1	8.35e-06	189	65	5	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	facs-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	8.57e-06	190	65	5	d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR LAMC1 SRPX SVEP1	8.79e-06	191	65	5	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR LAMC1 SRPX SVEP1	8.79e-06	191	65	5	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR LAMC1 SRPX SVEP1	8.79e-06	191	65	5	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH NGFR LAMC1 SRPX SVEP1	8.79e-06	191	65	5	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CFH LAMC1 SRPX SVEP1 AGAP1	9.01e-06	192	65	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAG2 PLPP1 LAMA3 NOTCH1 SEMA4C	9.01e-06	192	65	5	5012cc3ec0766f06af447463413422b484446c43
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	0f19b6384659a5bcc11b45dc2df8454b96ddf4cd
ToppCell	facs-Lung-24m-Endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	e10ef60a82f182680955a775adc6659325e92310
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	a586727dc23b0777770f54fc8d4fe5f30b68439f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	1d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell	PND10-Endothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 PLPP1 ADGRL2 CASZ1 NOTCH1	9.24e-06	193	65	5	f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FMO1 ADAMTS9 SVEP1 EGFL6	9.48e-06	194	65	5	79baee8b35b7707bbeb07c73b5e17b68bcd7bbc2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FMO1 ADAMTS9 SVEP1 EGFL6	9.48e-06	194	65	5	f6e348f1f35c526cad6c349f1fdd0bd92d18aa3c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPC1 ADAMTS9 LAMA3 CASZ1 ADCY9	9.48e-06	194	65	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FMO1 ADAMTS9 SVEP1 EGFL6	9.48e-06	194	65	5	421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FMO1 ADAMTS9 SVEP1 EGFL6	9.48e-06	194	65	5	ce599ed0dc181aea0584e426636de5098f34ebe6
ToppCell	distal-mesenchymal-Lipofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH FMO1 NGFR SRPX EGFL6	1.02e-05	197	65	5	865010edcd7e3f79f505fcef7b33882095994aa8
ToppCell	distal-mesenchymal-Lipofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH FMO1 NGFR SRPX EGFL6	1.02e-05	197	65	5	ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PLPP1 MME ADGRL2 LRP1B SVEP1	1.02e-05	197	65	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLPP1 MME ADGRL2 LRP1B SVEP1	1.02e-05	197	65	5	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NGFR LAMC1 SRPX LRP1B SVEP1	1.05e-05	198	65	5	abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NGFR LAMC1 SRPX LRP1B SVEP1	1.05e-05	198	65	5	ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell	3'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NGFR LAMC1 SRPX LRP1B SVEP1	1.05e-05	198	65	5	698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CFH PLPP1 LAMC1 ADGRL2 SVEP1	1.07e-05	199	65	5	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH NGFR SRPX SVEP1 EGFL6	1.07e-05	199	65	5	675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CFH PLPP1 LAMC1 SRPX SVEP1	1.07e-05	199	65	5	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CFH PLPP1 LAMC1 ADGRL2 SVEP1	1.07e-05	199	65	5	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLPP1 CNTNAP1 NGFR SRPX EGFL6	1.07e-05	199	65	5	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH NGFR SRPX SVEP1 EGFL6	1.07e-05	199	65	5	97d74985018816754d11a55b9fb689690ecb1374
ToppCell	distal-1-mesenchymal-Lipofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH FMO1 NGFR SRPX EGFL6	1.07e-05	199	65	5	a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH PAPPA2 FMO1 SRPX SVEP1	1.10e-05	200	65	5	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	Biopsy_Other_PF-Mesenchymal-Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CFH PAPPA2 FMO1 SRPX SVEP1	1.10e-05	200	65	5	9996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial-Proteoglycan-expressing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFH NGFR SRPX MME EGFL6	1.10e-05	200	65	5	94ef227b2162ba77af33b8cc8aaa4a7e3bdf79a7
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFH ADAMTS9 NGFR SRPX EGFL6	1.10e-05	200	65	5	c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH PAPPA2 FMO1 SRPX SVEP1	1.10e-05	200	65	5	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FMO1 LAMC1 SRPX SVEP1	1.10e-05	200	65	5	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	Biopsy_IPF-Mesenchymal-Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	PAPPA2 FMO1 PLPP1 SRPX SVEP1	1.10e-05	200	65	5	d8637f1e62d3fb9476dc51e1b1dc2f4b14b5fcd8
ToppCell	(5)_Fibroblast-E\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFH FMO1 PLPP1 SRPX SVEP1	1.10e-05	200	65	5	75e5ecb05e965e24d569aa2ef5cdf740b1528c06
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FMO1 PLPP1 SRPX SVEP1	1.10e-05	200	65	5	5c6520dc4c4693827f6680651785680b5883afb8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFH NGFR SRPX MME EGFL6	1.10e-05	200	65	5	429028c3112d279b26abf3296e01b1884b4b7fcb
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FMO1 LAMC1 SRPX SVEP1	1.10e-05	200	65	5	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CFH PAPPA2 FMO1 SRPX SVEP1	1.10e-05	200	65	5	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FMO1 LAMC1 SRPX SVEP1	1.10e-05	200	65	5	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	Club_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	CFH SYTL5 ZFY AGAP1	2.87e-05	120	65	4	7f85208f0455f3e634f8e7e81beea60b4ef1d2a5
ToppCell	droplet-Heart-nan-18m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN3 PLPP1 ADAMTS9 NOTCH1	3.48e-05	126	65	4	de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCell	remission-multiplets\|remission / disease stage, cell group and cell class	JAG2 CNTNAP1 LAMC1 ALPK2	6.68e-05	149	65	4	e9974260a5f2999b363f306cae005698c912893a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC5B MME LRP1B SVEP1	8.81e-05	160	65	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC5B MME LRP1B SVEP1	8.81e-05	160	65	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH FMO1 SRPX SVEP1	9.24e-05	162	65	4	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH FMO1 SRPX SVEP1	9.24e-05	162	65	4	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PLPP1 PIK3CA NOTCH1	9.46e-05	163	65	4	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZNF765 FMO1 L2HGDH SRPX	9.69e-05	164	65	4	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH FMO1 ADAMTS9 SVEP1	1.06e-04	168	65	4	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JAG2 FMO1 PLPP1 ADGRL2	1.09e-04	169	65	4	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLSTN3 NGFR LAMA3 ALPK2	1.09e-04	169	65	4	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	facs\|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 PLPP1 DUSP5 ZBTB21	1.14e-04	171	65	4	bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCell	facs\|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 PLPP1 DUSP5 ZBTB21	1.14e-04	171	65	4	5bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNOT6L ZNF549 NRG2 ZHX2	1.16e-04	172	65	4	6379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCell	facs-Lung-Endomucin-24m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 PLPP1 ADGRL2 NOTCH1	1.22e-04	174	65	4	ea27868d0373843a5137569ac3f9e3f8c92c7dcc
ToppCell	facs-Lung-Endomucin-24m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 PLPP1 LRP1B NOTCH1	1.22e-04	174	65	4	60a426bfe5625999f031776ab34f7bc0d2b331be
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 PLPP1 CASZ1 NOTCH1	1.24e-04	175	65	4	1c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 PLPP1 CASZ1 NOTCH1	1.27e-04	176	65	4	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SRPX SVEP1 EGFL6 AGAP1	1.27e-04	176	65	4	bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFH PAPPA2 MME EGFL6	1.27e-04	176	65	4	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SRPX SVEP1 EGFL6 AGAP1	1.30e-04	177	65	4	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EGF MUC5B MME GRM4	1.30e-04	177	65	4	a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EGF MUC5B MME GRM4	1.30e-04	177	65	4	363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	ADAMTS9 SYTL5 LAMC1 LRP1B	1.33e-04	178	65	4	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	ADAMTS9 SRPX ADGRL2 SYCN	1.36e-04	179	65	4	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR SRPX SVEP1	1.36e-04	179	65	4	6f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR SRPX SVEP1	1.36e-04	179	65	4	f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NGFR SRPX SVEP1	1.36e-04	179	65	4	a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLPP1 ADAMTS9 DUSP5 ADGRL2	1.39e-04	180	65	4	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	tumor_Lung-Fibroblasts-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	CFH FMO1 SRPX SVEP1	1.42e-04	181	65	4	53bcab4d6df4a3255d81877ba22fb95d4492ce9f
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH SRPX MME SVEP1	1.42e-04	181	65	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFH PAPPA2 MME EGFL6	1.45e-04	182	65	4	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CFH FMO1 ADGRL2	1.45e-04	182	65	4	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMC1 MME SVEP1	1.45e-04	182	65	4	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMC1 MME SVEP1	1.45e-04	182	65	4	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CFH FMO1 ADGRL2	1.45e-04	182	65	4	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CFH FMO1 ADGRL2	1.45e-04	182	65	4	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS9 LAMC1 SRPX SVEP1	1.45e-04	182	65	4	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FMO1 SRPX SVEP1	1.48e-04	183	65	4	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FMO1 SRPX SVEP1	1.48e-04	183	65	4	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FMO1 SRPX SVEP1	1.48e-04	183	65	4	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	COPD-Endothelial-VE_Venous\|COPD / Disease state, Lineage and Cell class	ADAMTS9 SRPX ADGRL2 SYCN	1.51e-04	184	65	4	44d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FMO1 SRPX SVEP1	1.54e-04	185	65	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NGFR LAMC1 SRPX SVEP1	1.54e-04	185	65	4	9faa35ceb89ccd2979072286f063687c9f846ce3
Computational	Neighborhood of CDKN1C	PAPPA2 SVEP1 EGFL6	2.13e-04	27	47	3	GNF2_CDKN1C
Drug	Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A	ZNF45 MUC5B ADGRL2 SVEP1 ADCY9 BEGAIN SEMA4C	1.64e-06	200	65	7	3682_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A	AVIL FSHB LAMA3 SRPX SVEP1 ZNF639	2.04e-05	196	65	6	4381_DN
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	PASK CLSTN3 ZNF549 FSHB ZNF639 BEGAIN	2.10e-05	197	65	6	3825_DN
Drug	Gliquidone [33342-05-1]; Down 200; 7.6uM; PC3; HT_HG-U133A	EGF RABGAP1L ZMYM2 L2HGDH MUC5B ZHX2	2.10e-05	197	65	6	7301_DN
Drug	Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	ZNF45 ZNF549 CNTNAP1 GRM4 SVEP1 ADCY9	2.10e-05	197	65	6	4096_DN
Drug	Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	PAPPA2 PASK RABGAP1L ZMYM2 ZNF639 RHO	2.16e-05	198	65	6	4343_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; PC3; HT_HG-U133A	CFH ADAMTS9 AVIL ADCY9 ZNF639 RHO	2.22e-05	199	65	6	5794_UP
Drug	Niacin [59-67-6]; Down 200; 32.4uM; PC3; HT_HG-U133A	JAG2 PASK ZNF45 RABGAP1L ZMYM2 CASZ1	2.22e-05	199	65	6	6702_DN
Drug	LSOs	NPC1 EGF PIK3CA FSHB GRM4	2.81e-05	124	65	5	CID000164701
Disease	scoliosis (implicated_via_orthology)	ADAMTS9 SSPOP	4.61e-05	5	64	2	DOID:0060249 (implicated_via_orthology)
Disease	fructose-1,6-bisphosphatase isozyme 2 measurement	CFH PCNX4	4.61e-05	5	64	2	EFO_0802556
Disease	Glioblastoma Multiforme	JAG2 EGF PIK3CA NOTCH1	1.01e-04	111	64	4	C1621958
Disease	chronic central serous retinopathy	CFH MEGF9	1.65e-04	9	64	2	EFO_0009363
Disease	Adult Hepatocellular Carcinoma	EGF PIK3CA	1.65e-04	9	64	2	C0279607
Disease	Fuchs endothelial corneal dystrophy	CFH LAMC1	2.06e-04	10	64	2	Orphanet_98974
Disease	gallbladder cancer (is_implicated_in)	EGF LRP1B	3.56e-04	13	64	2	DOID:3121 (is_implicated_in)
Disease	Prostatic Neoplasms	EGF PIK3CA NGFR LAMC1 MME LRP1B CASZ1	3.70e-04	616	64	7	C0033578
Disease	Malignant neoplasm of prostate	EGF PIK3CA NGFR LAMC1 MME LRP1B CASZ1	3.70e-04	616	64	7	C0376358
Disease	Glioblastoma	JAG2 EGF NOTCH1	6.84e-04	79	64	3	C0017636
Disease	Lewy body dementia (is_marker_for)	NGFR CHRNA4	7.73e-04	19	64	2	DOID:12217 (is_marker_for)
Disease	Giant Cell Glioblastoma	JAG2 EGF NOTCH1	8.18e-04	84	64	3	C0334588
Disease	Carcinoma, Pancreatic Ductal	JAG2 NOTCH1	1.24e-03	24	64	2	C0887833
Disease	congestive heart failure (biomarker_via_orthology)	NGFR MME CHRNA4	1.64e-03	107	64	3	DOID:6000 (biomarker_via_orthology)
Disease	Alzheimer disease, educational attainment	NPC1 LAMC1 LRP1B AGAP1	2.05e-03	247	64	4	EFO_0011015, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
DLKRCTYYETCATYG	AGAP3	221	Q96P47
LYHTYYECAGTCLGT	ERV3-1	46	Q14264
GTYNTRKYECCAEIY	CHRNA4	216	P43681
LEVDNVKYCGYCKYH	MLLT6	166	P55198
GDCYLVLYTYEVNGK	AVIL	421	O75366
DFICYCELTGYKGET	CNTNAP1	561	P78357
GSYYCKCHIGFELQY	EGFL6	196	Q8IUX8
DLKRCTYYETCATYG	AGAP1	201	Q9UPQ3
GDCSPQYSQICYYEI	CLSTN3	171	Q9BQT9
PYKGDIYCSDTALYC	BEGAIN	221	Q9BUH8
KDQGLYYCCIKNSYG	ALPK2	1851	Q86TB3
YYCCIKNSYGKVTAE	ALPK2	1856	Q86TB3
YEECKYEGCVYSKAT	CASZ1	651	Q86V15
TGYQYQVDRYTCKTC	GRM4	546	Q14833
CPGTYKYLEVQYECV	ADGRL2	116	O95490
YGVKAVYTCNEGYQL	CFH	106	P08603
ICKYYQKGYCAYGTR	MKRN2	36	Q9H000
AQCGCYDKDGNYYDV	MUC5B	1216	Q9HC84
EGLQCSCGIDYYTLK	RHO	181	P08100
KAYSVYDEEIGYCQG	RABGAP1	636	Q9Y3P9
GKLFYTFCGTIEYCA	PASK	1156	Q96RG2
TDYLGGYSCKCVAGY	NOTCH1	1161	P46531
YGTYKCLCTDGYEIQ	LRP1B	2986	Q9NZR2
YYYSIKDISIGGQCV	LAMA3	286	Q16787
SETPSRYYCYCGKVE	NFXL1	226	Q6ZNB6
YEYCQQKGISYKQCG	L2HGDH	121	Q9H9P8
FSCKNLIGGYYCDCI	JAG2	436	Q9Y219
ECGYTYCSINIKGLE	PCNX4	671	Q63HM2
SYCVNGGVCYYIEGI	NRG2	351	O14511
YYECTGIYKEACTAY	MME	231	P08473
SICDRCQDGYYGFSK	MEGF9	281	Q9H1U4
CAGYCYTRDLVYKDP	FSHB	46	P01225
YQGKYILKVCGCDEY	PIK3CA	246	P42336
ICKAYSVYDEDIGYC	RABGAP1L	606	Q5R372
CGIAYGDKRYNCEYS	NPC1	31	O15118
ICKYECKPGYYVAES	PAPPA2	1551	Q9BXP8
CGLGYRTLDIYCAKY	ADAMTS9	951	Q9P2N4
LDKYACNCVVGYIGE	EGF	996	P01133
GLCYCKALQSDYITY	FMO1	421	Q01740
EKISTLGDCYYCVAG	ADCY9	436	O60503
TGECLKCIYNTAGFY	LAMC1	846	P11047
KGGYETFYSEYPECC	DUSP5	126	Q16690
VLCDKYATRQLYGYC	CNOT6	196	Q9ULM6
GEAGLLLCYNYSCIY	GARNL3	711	Q5VVW2
YCYKTGGLYIFVKNC	SYTL5	416	Q8TDW5
YLDQVEVSYCSGYCP	SSPOP	5071	A2VEC9
INCSDGYIEYYICRG	PLPP1	141	O14494
YVCGTYAFQPKCTYV	SEMA4C	126	Q9C0C4
SRCEYYCSPGYTLKG	SRPX	141	P78539
ICEKGYYGKGLQYEC	SVEP1	306	Q4LDE5
YYGKGLQYECTACPS	SVEP1	311	Q4LDE5
VLCDKYATRQLYGYC	CNOT6L	196	Q96LI5
YKCTQCGKAFSCYYY	ZNF823	276	P16415
AKGAYICTYCGKAYR	ZBTB21	666	Q9ULJ3
PYKCNECGKVYSQYS	ZNF616	576	Q08AN1
EGAYQCSECGKSFIY	ZNF549	386	Q6P9A3
LSEGIYLCQYCEYST	ZNF639	426	Q9UID6
YLCQYCEYSTGQIED	ZNF639	431	Q9UID6
VCRCAYGYYQDETTG	NGFR	106	P08138
YGYYQDETTGRCEAC	NGFR	111	P08138
TQLYCDGVGVQYKDY	TTC3	41	P53804
SIYYLCLGIQEYLCG	ZMYM2	1141	Q9UBW7
YICEVCGKGFSQRAY	ZNF112	721	Q9UJU3
GGYECKYCPYSTQNL	ZHX2	76	Q9Y6X8
YKCNECGKTFSQTYY	ZNF765	271	Q7L2R6
LYDKSDPYYENCCGG	SYCN	41	Q0VAF6
YKCEECGVGFSQRSY	ZNF45	276	Q02386
THSGRKVYQCEYCEY	ZFY	736	P08048
FYHTGTKCYQGEYCK	ZC3H8	251	Q8N5P1