Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpre-mRNA intronic binding

RBM7 SOX9 HNRNPL

2.67e-0614403GO:0097157
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NFE2L3 SOX9 HOXB3 TBXT CHD7 ASCL3 PAX8 BATF TCF7L1 TP73 SMAD9

9.75e-0514594011GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NFE2L3 SOX9 HOXB3 TBXT CHD7 PAX8 BATF TCF7L1 TP73 SMAD9

1.29e-0412444010GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NFE2L3 SOX9 HOXB3 TBXT CHD7 PAX8 BATF TCF7L1 TP73 SMAD9

1.54e-0412714010GO:0000987
GeneOntologyMolecularFunctionpre-mRNA binding

RBM7 SOX9 HNRNPL

2.85e-0464403GO:0036002
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NFE2L3 SOX9 HOXB3 TBXT ASCL3 PAX8 BATF TCF7L1 TP73 SMAD9

3.61e-0414124010GO:0000981
GeneOntologyBiologicalProcessdevelopmental growth

IGSF10 SOX9 ROBO1 CHD7 IFT80 SIK3 ASCL3 ATXN2 AZGP1 TP73

8.65e-069114110GO:0048589
GeneOntologyBiologicalProcessgrowth

IGSF10 SOX9 ROBO1 CHD7 IFT80 SIK3 ASCL3 ATXN2 AZGP1 TP73 CEACAM1

2.02e-0512354111GO:0040007
GeneOntologyBiologicalProcessmetanephric nephron tubule formation

SOX9 PAX8

2.31e-054412GO:0072289
GeneOntologyBiologicalProcessregulation of T-helper 17 cell differentiation

MALT1 BATF RC3H1

3.82e-0533413GO:2000319
GeneOntologyBiologicalProcessmetanephric tubule formation

SOX9 PAX8

5.75e-056412GO:0072174
GeneOntologyBiologicalProcessmetanephric nephron tubule morphogenesis

SOX9 PAX8

8.04e-057412GO:0072282
GeneOntologyBiologicalProcessbone morphogenesis

SOX9 TBXT IFT80 SIK3

1.06e-04124414GO:0060349
GeneOntologyBiologicalProcessT-helper 17 cell differentiation

MALT1 BATF RC3H1

1.11e-0447413GO:0072539
GeneOntologyBiologicalProcesscartilage development involved in endochondral bone morphogenesis

SOX9 IFT80 SIK3

1.11e-0447413GO:0060351
GeneOntologyBiologicalProcessregulation of T-helper 17 type immune response

MALT1 BATF RC3H1

1.11e-0447413GO:2000316
GeneOntologyBiologicalProcesscartilage development

SOX9 HOXB3 IFT80 SIK3 SMAD9

1.15e-04243415GO:0051216
GeneOntologyBiologicalProcessmulticellular organism growth

CHD7 IFT80 SIK3 ATXN2 AZGP1

1.29e-04249415GO:0035264
GeneOntologyBiologicalProcessanimal organ morphogenesis

SOX9 ROBO1 HOXB3 TBXT PRKCI CHD7 IFT80 SIK3 PAX8 CEACAM1

1.45e-0412694110GO:0009887
GeneOntologyBiologicalProcessbone development

SOX9 TBXT IFT80 SIK3 SMAD9

1.70e-04264415GO:0060348
GeneOntologyBiologicalProcessmetanephric tubule morphogenesis

SOX9 PAX8

1.72e-0410412GO:0072173
GeneOntologyBiologicalProcessregulation of T cell receptor signaling pathway

MALT1 RC3H1 CEACAM1

1.78e-0455413GO:0050856
GeneOntologyBiologicalProcessskeletal system development

SOX9 HOXB3 TBXT CHD7 IFT80 SIK3 SMAD9

1.88e-04615417GO:0001501
GeneOntologyBiologicalProcessregulation of T-helper cell differentiation

MALT1 BATF RC3H1

1.98e-0457413GO:0045622
GeneOntologyBiologicalProcessT cell activation involved in immune response

MALT1 BATF RC3H1 CEACAM1

2.10e-04148414GO:0002286
GeneOntologyBiologicalProcessskeletal system morphogenesis

SOX9 HOXB3 TBXT IFT80 SIK3

2.13e-04277415GO:0048705
GeneOntologyBiologicalProcessregulation of cell development

ROBO1 MALT1 HOXB3 PRKCI CHD7 BATF RC3H1 TP73 CEACAM1

2.43e-041095419GO:0060284
GeneOntologyBiologicalProcessT-helper 17 type immune response

MALT1 BATF RC3H1

2.79e-0464413GO:0072538
GeneOntologyBiologicalProcessnegative regulation of mesenchymal cell apoptotic process

SOX9 PAX8

2.97e-0413412GO:2001054
GeneOntologyBiologicalProcessregulation of somatic stem cell population maintenance

PAX8 TCF7L1

2.97e-0413412GO:1904672
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SOX9 HOXB3 TBXT CHD7 ASCL3 PAX8 BATF TCF7L1 TP73 SMAD9

3.05e-0413904110GO:0045944
GeneOntologyBiologicalProcessstem cell differentiation

SOX9 TBXT IFT80 BATF TCF7L1

3.36e-04306415GO:0048863
GeneOntologyBiologicalProcessgrowth plate cartilage chondrocyte differentiation

SOX9 IFT80

3.46e-0414412GO:0003418
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell differentiation

MALT1 BATF RC3H1

4.12e-0473413GO:0043370
GeneOntologyBiologicalProcessregulation of antigen receptor-mediated signaling pathway

MALT1 RC3H1 CEACAM1

4.81e-0477413GO:0050854
GeneOntologyBiologicalProcessregulation of mesenchymal cell apoptotic process

SOX9 PAX8

5.14e-0417412GO:2001053
GeneOntologyBiologicalProcessendochondral bone morphogenesis

SOX9 IFT80 SIK3

5.19e-0479413GO:0060350
GeneOntologyBiologicalProcessnegative regulation of cell population proliferation

SOX9 ROBO1 IFT80 CLMN RC3H1 AZGP1 TP73 CEACAM1

5.23e-04961418GO:0008285
GeneOntologyBiologicalProcessconnective tissue development

SOX9 HOXB3 IFT80 SIK3 SMAD9

5.66e-04343415GO:0061448
GeneOntologyBiologicalProcessrenal vesicle morphogenesis

SOX9 PAX8

5.78e-0418412GO:0072077
GeneOntologyBiologicalProcesspositive regulation of epithelial cell differentiation

SOX9 PAX8 TP73

5.79e-0482413GO:0030858
GeneOntologyBiologicalProcesstissue morphogenesis

SOX9 ROBO1 TBXT CHD7 PAX8 TCF7L1 CEACAM1

6.25e-04750417GO:0048729
GeneOntologyBiologicalProcessembryonic organ morphogenesis

SOX9 HOXB3 TBXT CHD7 PAX8

6.28e-04351415GO:0048562
GeneOntologyBiologicalProcessmesenchymal cell apoptotic process

SOX9 PAX8

6.45e-0419412GO:0097152
GeneOntologyBiologicalProcessrenal vesicle development

SOX9 PAX8

6.45e-0419412GO:0072087
GeneOntologyBiologicalProcesschondrocyte differentiation involved in endochondral bone morphogenesis

SOX9 IFT80

7.16e-0420412GO:0003413
GeneOntologyBiologicalProcessgland development

SOX9 ROBO1 HOXB3 ASCL3 PAX8 CEACAM1

7.67e-04558416GO:0048732
GeneOntologyBiologicalProcessmetanephric nephron tubule development

SOX9 PAX8

7.90e-0421412GO:0072234
GeneOntologyBiologicalProcessT-helper cell differentiation

MALT1 BATF RC3H1

8.10e-0492413GO:0042093
GeneOntologyBiologicalProcessregulation of alpha-beta T cell differentiation

MALT1 BATF RC3H1

8.36e-0493413GO:0046637
GeneOntologyBiologicalProcessregulation of multicellular organism growth

CHD7 ATXN2 AZGP1

8.36e-0493413GO:0040014
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation involved in immune response

MALT1 BATF RC3H1

8.62e-0494413GO:0002294
GeneOntologyBiologicalProcesspositive regulation of branching involved in ureteric bud morphogenesis

SOX9 PAX8

8.68e-0422412GO:0090190
GeneOntologyBiologicalProcessalpha-beta T cell differentiation involved in immune response

MALT1 BATF RC3H1

8.89e-0495413GO:0002293
GeneOntologyBiologicalProcessregulation of epithelial cell differentiation

SOX9 PAX8 TP73 CEACAM1

8.89e-04217414GO:0030856
GeneOntologyBiologicalProcessmetanephric nephron epithelium development

SOX9 PAX8

9.50e-0423412GO:0072243
GeneOntologyBiologicalProcessP-body assembly

ATXN2 RC3H1

9.50e-0423412GO:0033962
GeneOntologyBiologicalProcessmetanephric nephron morphogenesis

SOX9 PAX8

9.50e-0423412GO:0072273
GeneOntologyBiologicalProcessnephron tubule formation

SOX9 PAX8

9.50e-0423412GO:0072079
GeneOntologyBiologicalProcessalpha-beta T cell activation involved in immune response

MALT1 BATF RC3H1

9.73e-0498413GO:0002287
GeneOntologyBiologicalProcesslimb development

SOX9 CHD7 IFT80 SIK3

1.00e-03224414GO:0060173
GeneOntologyBiologicalProcessappendage development

SOX9 CHD7 IFT80 SIK3

1.00e-03224414GO:0048736
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell activation

MALT1 BATF RC3H1

1.03e-03100413GO:2000514
GeneOntologyBiologicalProcessnegative regulation of epithelial cell proliferation

SOX9 ROBO1 IFT80 CEACAM1

1.03e-03226414GO:0050680
GeneOntologyBiologicalProcessanterior/posterior axis specification, embryo

TBXT TCF7L1

1.03e-0324412GO:0008595
GeneOntologyBiologicalProcessregulation of branching involved in ureteric bud morphogenesis

SOX9 PAX8

1.03e-0324412GO:0090189
GeneOntologyBiologicalProcessnotochord development

SOX9 TBXT

1.03e-0324412GO:0030903
GeneOntologyBiologicalProcesstripartite regional subdivision

TBXT TCF7L1

1.03e-0324412GO:0007351
GeneOntologyBiologicalProcessT cell differentiation involved in immune response

MALT1 BATF RC3H1

1.12e-03103413GO:0002292
GeneOntologyBiologicalProcessregulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

MALT1 BATF RC3H1 CEACAM1

1.19e-03235414GO:0002822
GeneOntologyBiologicalProcessmetanephric tubule development

SOX9 PAX8

1.22e-0326412GO:0072170
GeneOntologyBiologicalProcesssomatic stem cell population maintenance

SOX9 PAX8 TCF7L1

1.29e-03108413GO:0035019
GeneOntologyBiologicalProcessnerve development

UNC13B HOXB3 CHD7

1.32e-03109413GO:0021675
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

SOX9 ROBO1 PAX8

1.36e-03110413GO:2000027
GeneOntologyBiologicalProcessmetanephric epithelium development

SOX9 PAX8

1.41e-0328412GO:0072207
GeneOntologyBiologicalProcessdense core granule localization

UNC13B TANC2

1.41e-0328412GO:0032253
GeneOntologyBiologicalProcessmetanephros morphogenesis

SOX9 PAX8

1.51e-0329412GO:0003338
GeneOntologyBiologicalProcessgrowth plate cartilage development

SOX9 IFT80

1.51e-0329412GO:0003417
GeneOntologyBiologicalProcesslymphocyte activation involved in immune response

MALT1 BATF RC3H1 CEACAM1

1.52e-03251414GO:0002285
GeneOntologyBiologicalProcessregulation of adaptive immune response

MALT1 BATF RC3H1 CEACAM1

1.54e-03252414GO:0002819
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

SOX9 ROBO1 MALT1 PRKCI PAX8 TP73 CEACAM1 SMAD9

1.60e-031141418GO:0045597
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation

MALT1 BATF RC3H1

1.70e-03119413GO:0043367
GeneOntologyBiologicalProcessepithelium development

SOX9 ROBO1 TBXT CHD7 IFT80 ASCL3 PAX8 TP73 CEACAM1

2.01e-031469419GO:0060429
GeneOntologyBiologicalProcesshead development

SOX9 ROBO1 HOXB3 CHD7 ATXN2 TP73 SMAD9

2.03e-03919417GO:0060322
GeneOntologyBiologicalProcessthyroid gland development

HOXB3 PAX8

2.08e-0334412GO:0030878
GeneOntologyBiologicalProcessinnervation

UNC13B CHD7

2.08e-0334412GO:0060384
GeneOntologyBiologicalProcesssecretory granule localization

UNC13B TANC2

2.08e-0334412GO:0032252
GeneOntologyBiologicalProcessinner ear morphogenesis

SOX9 CHD7 PAX8

2.14e-03129413GO:0042472
GeneOntologyBiologicalProcesscentral nervous system development

SOX9 ROBO1 HOXB3 CHD7 IFT80 ATXN2 TP73 SMAD9

2.16e-031197418GO:0007417
GeneOntologyBiologicalProcessblastoderm segmentation

TBXT TCF7L1

2.20e-0335412GO:0007350
GeneOntologyBiologicalProcesscardiac septum development

ROBO1 CHD7 PAX8

2.39e-03134413GO:0003279
GeneOntologyBiologicalProcessregionalization

ROBO1 HOXB3 TBXT PAX8 TCF7L1

2.47e-03478415GO:0003002
GeneOntologyBiologicalProcesshemopoiesis

MALT1 HOXB3 CHD7 IFT80 KMT2E BATF RC3H1 CEACAM1

2.47e-031223418GO:0030097
GeneOntologyBiologicalProcessmetanephric nephron development

SOX9 PAX8

2.59e-0338412GO:0072210
GeneOntologyBiologicalProcessregulation of kidney development

SOX9 PAX8

2.59e-0338412GO:0090183
GeneOntologyBiologicalProcessepidermal growth factor receptor signaling pathway

SOX9 ERBIN CEACAM1

2.65e-03139413GO:0007173
GeneOntologyBiologicalProcessaortic valve morphogenesis

SOX9 ROBO1

2.73e-0339412GO:0003180
GeneOntologyBiologicalProcessendochondral bone growth

SOX9 IFT80

2.73e-0339412GO:0003416
GeneOntologyBiologicalProcessregulation of alpha-beta T cell activation

MALT1 BATF RC3H1

2.76e-03141413GO:0046634
GeneOntologyBiologicalProcesspositive regulation of animal organ morphogenesis

SOX9 ROBO1

3.01e-0341412GO:0110110
GeneOntologyCellularComponentchromatin

NFE2L3 SOX9 HOXB3 TBXT CHD7 KMT2E ASCL3 PAX8 BATF TCF7L1 HNRNPL TP73 SMAD9

3.90e-0614804213GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

NFE2L3 SOX9 ASCL3 PAX8 BATF TCF7L1 SMAD9

1.68e-04596427GO:0005667
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

NFE2L3 ASCL3 BATF TCF7L1 SMAD9

2.06e-04272425GO:0090575
MousePhenodecreased round window size

CHD7 PAX8

1.82e-053352MP:0030411
MousePhenoabnormal round window morphology

CHD7 PAX8

6.06e-055352MP:0004480
MousePhenointrahepatic cholestasis

SIK3 ATXN2

6.06e-055352MP:0005415
MousePhenoabnormal stapes crus morpholgy

CHD7 PAX8

6.06e-055352MP:0030407
MousePhenoabnormal pelvic girdle bone morphology

SOX9 TBXT IFT80 SIK3

6.32e-0587354MP:0004509
MousePhenoneonatal lethality

SOX9 ROBO1 HOXB3 TBXT SIK3 KMT2E TCF7L1 RC3H1 KIF21A

1.14e-04799359MP:0002058
MousePhenoabnormal effector T cell number

CHD7 SIK3 KMT2E BATF RC3H1

1.40e-04203355MP:0013762
MousePhenoabsent somites

TBXT PRKCI TCF7L1

1.54e-0442353MP:0006386
MousePhenoperiorbital edema

CHD7 TP73

1.69e-048352MP:0001788
MousePhenocholestasis

SIK3 ATXN2

2.17e-049352MP:0000610
MousePhenofailure of somite differentiation

TBXT PRKCI TCF7L1

2.60e-0450353MP:0001690
MousePhenoabnormal periorbital region morphology

CHD7 TP73

2.71e-0410352MP:0030038
MousePhenoperinatal lethality

SOX9 ROBO1 HOXB3 TBXT IFT80 SIK3 KMT2E TCF7L1 RC3H1 KIF21A

3.23e-0411303510MP:0002081
MousePhenoabnormal T follicular helper cell number

BATF RC3H1

3.30e-0411352MP:0010185
MousePhenofusion of glossopharyngeal and vagus nerve

HOXB3 CHD7

3.30e-0411352MP:0004568
MousePhenoabnormal T follicular helper cell morphology

BATF RC3H1

3.96e-0412352MP:0010184
MousePhenoabnormal limb development

SOX9 TBXT CHD7 TCF7L1

3.96e-04140354MP:0006279
DomainIGc2

IGSF10 ROBO1 MALT1 CEACAM1

1.56e-03235404SM00408
DomainIg_sub2

IGSF10 ROBO1 MALT1 CEACAM1

1.56e-03235404IPR003598
DomainbZIP_1

NFE2L3 BATF

2.40e-0334402PF00170
DomainTF_DNA-bd

NFE2L3 BATF

2.84e-0337402IPR008917
DomainIG_LIKE

IGSF10 ROBO1 MALT1 AZGP1 CEACAM1

3.79e-03491405PS50835
DomainIg-like_dom

IGSF10 ROBO1 MALT1 AZGP1 CEACAM1

4.20e-03503405IPR007110
DomainBRLZ

NFE2L3 BATF

5.54e-0352402SM00338
DomainHMG_box

SOX9 TCF7L1

5.75e-0353402PF00505
Domainp53-like_TF_DNA-bd

TBXT TP73

5.75e-0353402IPR008967
DomainBZIP

NFE2L3 BATF

5.75e-0353402PS50217
DomainBZIP_BASIC

NFE2L3 BATF

5.75e-0353402PS00036
DomainbZIP

NFE2L3 BATF

5.97e-0354402IPR004827
DomainHMG_BOX_2

SOX9 TCF7L1

5.97e-0354402PS50118
DomainHMG

SOX9 TCF7L1

5.97e-0354402SM00398
Domain-

SOX9 TCF7L1

6.18e-03554021.10.30.10
DomainC1_1

UNC13B PRKCI

6.63e-0357402PF00130
DomainIg_I-set

IGSF10 ROBO1 CEACAM1

7.77e-03190403IPR013098
DomainI-set

IGSF10 ROBO1 CEACAM1

7.77e-03190403PF07679
DomainZF_DAG_PE_1

UNC13B PRKCI

8.29e-0364402PS00479
DomainZF_DAG_PE_2

UNC13B PRKCI

8.29e-0364402PS50081
DomainC1

UNC13B PRKCI

8.54e-0365402SM00109
DomainHMG_box_dom

SOX9 TCF7L1

8.54e-0365402IPR009071
DomainPE/DAG-bd

UNC13B PRKCI

8.80e-0366402IPR002219
DomainIg_V-set

IGSF10 ROBO1 CEACAM1

8.81e-03199403IPR013106
DomainIg_2

MALT1 CEACAM1

1.07e-0273402PF13895
DomainIGv

IGSF10 ROBO1

1.12e-0275402SM00406
DomainIG

IGSF10 ROBO1 MALT1 CEACAM1

1.23e-02421404SM00409
DomainIg_sub

IGSF10 ROBO1 MALT1 CEACAM1

1.23e-02421404IPR003599
Pubmed

A census of human transcription factors: function, expression and evolution.

NFE2L3 SOX9 HOXB3 TBXT CENPT ASCL3 PAX8 BATF TCF7L1 TP73 SMAD9

1.26e-08908441119274049
Pubmed

NFATc1 balances quiescence and proliferation of skin stem cells.

SOX9 TCF7L1 SMAD9

6.81e-071444318243104
Pubmed

Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.

MALT1 RC3H1

1.56e-06244237988467
Pubmed

The evaluation of SOX9 expression and its relationship with carcinoembryonic antigen-related cell adhesion molecule 1 in gastric neoplastic and nonneoplastic lesions.

SOX9 CEACAM1

1.56e-06244222209504
Pubmed

Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.

SOX9 TCF7L1 TP73

4.26e-062544336196585
Pubmed

Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis.

SOX9 TBXT

4.69e-06344218820665
Pubmed

Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1.

HNRNPL CEACAM1

4.69e-06344229720400
Pubmed

Malignant tumors with clear cell morphology: a comparative immunohistochemical study with renal cell carcinoma antibody, Pax8, steroidogenic factor 1, and brachyury.

TBXT PAX8

4.69e-06344223218904
Pubmed

SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells.

SOX9 CEACAM1

9.37e-06444226885752
Pubmed

Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M.

HNRNPL CEACAM1

9.37e-06444221398516
Pubmed

Axon guidance genes control hepatic artery development.

SOX9 ROBO1 CEACAM1

1.31e-053644337497580
Pubmed

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor.

SOX9 TBXT

1.56e-05544236154671
Pubmed

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.

THSD4 TNS1

1.56e-05544221965014
Pubmed

Generation and characterization of a Dkk4-Cre knock-in mouse line.

SOX9 TBXT

2.34e-05644237435631
Pubmed

ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.

SOX9 PRKCI

2.34e-05644230126902
Pubmed

Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion.

SOX9 SMAD9

2.34e-05644227250101
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 PRKCI CHD7 SIK3 ATXN2 TNS1 ERBIN KIF21A

2.46e-0596344828671696
Pubmed

Formation of the rete testis during mouse embryonic development.

SOX9 PAX8

3.27e-05744232852840
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

NFE2L3 SOX9 PRKCI SIK3 KMT2E RC3H1 CEACAM1

3.40e-0573044734857952
Pubmed

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.

MALT1 RC3H1

4.36e-05844225282160
Pubmed

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5.

HOXB3 KMT2E

4.36e-05844218952892
Pubmed

Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus.

SOX9 SMAD9

4.36e-05844223064761
Pubmed

SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling.

TBXT SMAD9

4.36e-05844230446626
Pubmed

Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.

SOX9 SMAD9

4.36e-05844223458899
Pubmed

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

THSD4 SOX9 TNS1

5.55e-055844323284291
Pubmed

Genome-wide association study identifies five loci associated with lung function.

THSD4 TNS1

5.60e-05944220010834
Pubmed

Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia.

SOX9 TBXT

5.60e-05944217260385
Pubmed

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.

SOX9 SMAD9

5.60e-05944215123739
Pubmed

Human transcription factor protein interaction networks.

SOX9 PRR12 TBXT CHD7 ATXN2 PAX8 ERBIN RC3H1 HNRNPL

6.28e-05142944935140242
Pubmed

TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes.

SOX9 TBXT

6.99e-051044212646629
Pubmed

Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice.

TBXT BATF

6.99e-051044237163450
Pubmed

SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast.

TBXT SMAD9

6.99e-051044212351174
Pubmed

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.

TBXT SMAD9

6.99e-051044211566864
Pubmed

Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiation.

SOX9 SMAD9

6.99e-051044226058470
Pubmed

The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development.

SOX9 SMAD9

6.99e-051044222300732
Pubmed

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.

SOX9 TCF7L1

6.99e-051044222393260
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

PRKCI LARS2 ATXN2 HNRNPL

8.36e-0518244432239614
Pubmed

Wtap is required for differentiation of endoderm and mesoderm in the mouse embryo.

TBXT SMAD9

8.54e-051144218224709
Pubmed

Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification.

SOX9 SMAD9

8.54e-051144220534695
Pubmed

Sox9 is required for notochord maintenance in mice.

SOX9 TBXT

8.54e-051144216678811
Pubmed

SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways.

SOX9 TP73

8.54e-051144234286693
Pubmed

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo.

SOX9 SMAD9

8.54e-051144215781876
Pubmed

Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development.

SOX9 SMAD9

8.54e-051144219501582
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

UNC13B ROBO1 CHD7 ATXN2 RC3H1

8.78e-0535844532460013
Pubmed

BMPR-II is dispensable for formation of the limb skeleton.

SOX9 SMAD9

1.02e-041244221538804
Pubmed

Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice.

SOX9 SMAD9

1.02e-041244223891934
Pubmed

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.

SOX9 PRKCI

1.02e-041244221287656
Pubmed

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

SOX9 TCF7L1

1.02e-041244232414917
Pubmed

Deficiency of Fam20b-Catalyzed Glycosaminoglycan Chain Synthesis in Neural Crest Leads to Cleft Palate.

SOX9 SMAD9

1.02e-041244237298583
Pubmed

Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.

SOX9 SMAD9

1.02e-041244215923624
Pubmed

Impaired Annulus Fibrosus Development and Vertebral Fusion Cause Severe Scoliosis in Mice with Deficiency of c-Jun NH2-Terminal Kinases 1 and 2.

SOX9 SMAD9

1.02e-041244230664861
Pubmed

The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.

CENPT TOP3A

1.21e-041344224699063
Pubmed

Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling.

SOX9 SMAD9

1.21e-041344234557486
Pubmed

Wnt5a is essential for intestinal elongation in mice.

SOX9 PRKCI

1.21e-041344219100728
Pubmed

A branching morphogenesis program governs embryonic growth of the thyroid gland.

SOX9 PAX8

1.21e-041344229361553
Pubmed

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.

SOX9 TCF7L1

1.21e-041344219718027
Pubmed

Dynamics of BMP signaling in limb bud mesenchyme and polydactyly.

SOX9 SMAD9

1.21e-041344225034710
Pubmed

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad.

SOX9 PAX8

1.21e-041344235613264
Pubmed

Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis.

SOX9 SMAD9

1.41e-041444223238123
Pubmed

Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.

SOX9 SMAD9

1.41e-041444230413887
Pubmed

Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties.

SOX9 TBXT

1.41e-041444217289022
Pubmed

Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.

SOX9 PAX8

1.41e-041444231534052
Pubmed

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium.

SOX9 CEACAM1

1.41e-041444218794798
Pubmed

Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5.

TBXT PRKCI

1.41e-041444223690951
Pubmed

Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.

SOX9 SMAD9

1.63e-041544220404326
Pubmed

Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.

SOX9 SMAD9

1.63e-041544231618630
Pubmed

Rap1b Is an Effector of Axin2 Regulating Crosstalk of Signaling Pathways During Skeletal Development.

SOX9 SMAD9

1.63e-041544228520221
Pubmed

β1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs.

SOX9 TBXT

1.63e-041544233051257
Pubmed

Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.

TBXT TCF7L1

1.63e-041544223487311
Pubmed

New semidominant mutations that affect mouse development.

SOX9 TBXT

1.86e-041644215384171
Pubmed

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

TBXT CHD7

1.86e-041644210932191
Pubmed

Mutant Lef1 controls Gata6 in sebaceous gland development and cancer.

SOX9 TCF7L1

1.86e-041644230886049
Pubmed

Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.

SOX9 PRKCI

1.86e-041644226657766
Pubmed

Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii.

SOX9 PAX8

1.86e-041644236165446
Pubmed

Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.

SOX9 SMAD9

1.86e-041644229317485
Pubmed

RAB23 regulates musculoskeletal development and patterning.

SOX9 SMAD9

1.86e-041644236910145
Pubmed

Enhanced BMP signaling leads to enlarged nasal cartilage formation in mice.

SOX9 SMAD9

1.86e-041644237640003
Pubmed

Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain.

TBXT SMAD9

1.86e-041644220730911
Pubmed

Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.

SOX9 SMAD9

2.10e-041744227606421
Pubmed

Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.

SOX9 TBXT

2.10e-041744238865240
Pubmed

SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice.

SOX9 SIK3

2.10e-041744222318228
Pubmed

Disrupted tenogenesis in masseter as a potential cause of micrognathia.

SOX9 SMAD9

2.10e-041744236257937
Pubmed

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

SOX9 TBXT

2.10e-041744219753101
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

SOX9 SMAD9

2.36e-041844235503090
Pubmed

Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice.

SOX9 PAX8

2.36e-041844226776520
Pubmed

Tcf3: a transcriptional regulator of axis induction in the early embryo.

TBXT TCF7L1

2.36e-041844214668413
Pubmed

Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.

SOX9 TCF7L1

2.36e-041844224735878
Pubmed

Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation.

SOX9 SMAD9

2.36e-041844223717575
Pubmed

Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.

SOX9 SMAD9

2.64e-041944227056911
Pubmed

Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.

SOX9 TBXT

2.64e-041944235988542
Pubmed

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.

SOX9 SMAD9

2.64e-041944229618652
Pubmed

EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.

SOX9 PRKCI

2.64e-041944229058721
Pubmed

vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis.

SOX9 PAX8

2.93e-042044220040500
Pubmed

Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode.

SOX9 PAX8

2.93e-042044218495817
Pubmed

Molecular evolution of Sry and Sox gene.

SOX9 TCF7L1

2.93e-042044211404013
Pubmed

Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region.

SOX9 SMAD9

2.93e-042044220660756
Pubmed

Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.

TBXT TCF7L1

2.93e-042044222573616
Pubmed

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.

TBXT SMAD9

2.93e-042044229412136
Pubmed

Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.

SOX9 PRKCI

2.93e-042044227616714
Pubmed

Sox9 is required for invagination of the otic placode in mice.

SOX9 PAX8

2.93e-042044218377888
InteractionZNF609 interactions

THSD4 SOX9 TBXT PRKCI PAX8 HNRNPL

4.76e-07146416int:ZNF609
InteractionKDM6A interactions

SOX9 TBXT PAX8 HNRNPL SMAD9

1.87e-05162415int:KDM6A
InteractionPRR12 interactions

SOX9 PRR12 TBXT PAX8

3.04e-0588414int:PRR12
InteractionNFIA interactions

SOX9 PRR12 TBXT PAX8 HNRNPL

3.82e-05188415int:NFIA
InteractionMAN1C1 interactions

HNRNPL SMAD9

6.03e-056412int:MAN1C1
InteractionNFIC interactions

SOX9 PRR12 TBXT PAX8 HNRNPL

6.47e-05210415int:NFIC
Cytoband15q23

THSD4 CT62

8.28e-044444215q23
Cytoband2p23.3

TMEM214 AGBL5

1.96e-03684422p23.3
CytobandEnsembl 112 genes in cytogenetic band chr15q23

THSD4 CT62

1.96e-0368442chr15q23
Cytoband7q22.1

KMT2E AZGP1

5.31e-031134427q22.1
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

THSD4 PIP5K1B SIK3 TNS1 CLMN

5.44e-06155435M39246
CoexpressionGSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP

NFE2L3 CHD7 IFT80 KMT2E RC3H1

1.87e-05200435M9258
CoexpressionKIM_WT1_TARGETS_UP

SOX9 PRKCI CHD7 TNS1 HNRNPL

2.77e-05217435M9128
CoexpressionMAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP

NFE2L3 MALT1 PRKCI

4.20e-0541433M1422
CoexpressionALCALAY_AML_BY_NPM1_LOCALIZATION_UP

UNC13B NFE2L3 HOXB3 CHD7

8.18e-05140434M9377
CoexpressionBENPORATH_ES_CORE_NINE

NFE2L3 TCF7L1

9.40e-059432M4740
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200

SOX9 ROBO1 CHD7 PAX8

5.02e-0662394gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

THSD4 SOX9 ROBO1 HOXB3 CHD7 PAX8 KIF21A

7.07e-06398397gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlaskidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

THSD4 HOXB3 CHD7 PAX8 TCF7L1

3.28e-05202395gudmap_kidney_P2_CapMes_Crym_k3_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

THSD4 NFE2L3 SOX9 ROBO1 HOXB3 CHD7 PAX8 KIF21A

7.35e-05783398gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4

UNC13B CHD7 LARS2 KIF21A

1.21e-04139394Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

THSD4 ROBO1 CHD7 PAX8

1.54e-04148394gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlaskidney_P2_CapMes_Crym_top-relative-expression-ranked_500

THSD4 HOXB3 CHD7 PAX8 TCF7L1

1.84e-04291395gudmap_kidney_P2_CapMes_Crym_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

ROBO1 CHD7 PAX8

2.31e-0465393gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

SOX9 ROBO1 CHD7 PAX8

2.34e-04165394gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500

UNC13B SOX9 CHD7 LARS2 PAX8 KIF21A

2.67e-04496396Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2

CHD7 CENPT LARS2 KIF21A

2.80e-04173394Facebase_RNAseq_e10.5_Maxillary Arch_1000_K2
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200

SOX9 ROBO1 CHD7 PAX8

2.93e-04175394gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100

SOX9 CHD7

2.95e-0414392gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_100
CoexpressionAtlase10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500_1

CHD7 TCF7L1

3.88e-0416392Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500_1
CoexpressionAtlasgudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0

UNC13B THSD4 SOX9 PRR12 CHD7 CENPT LARS2 PAX8 TOP3A

4.06e-041275399gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
CoexpressionAtlaskidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

HOXB3 CHD7 PAX8 TCF7L1

4.33e-04194394gudmap_kidney_P0_CapMes_Crym_k2_500
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500

HOXB3 CHD7 PAX8 TCF7L1

4.50e-04196394gudmap_kidney_P1_CapMes_Crym_k4_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

THSD4 ROBO1 HOXB3 CHD7 PAX8

5.53e-04370395gudmap_kidney_P3_CapMes_Crym_500
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TANC2 HOXB3 PAX8 TCF7L1

1.02e-06188435e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TANC2 HOXB3 PAX8 TCF7L1

1.08e-0619043511d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

UNC13B THSD4 PIP5K1B PRKCI TCF7L1

1.13e-06192435efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFE2L3 SOX9 PIP5K1B ASCL3 AZGP1

1.16e-061934355879efb38e6b3bf8c33c9a773632b1d726e3c153
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFE2L3 SOX9 PIP5K1B ASCL3 AZGP1

1.16e-06193435725115a5ce3ef520b3ef469e96b8219b4c723fdd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFE2L3 SOX9 PIP5K1B ASCL3 AZGP1

1.16e-06193435abd7bcf318a2d895d8811c2ada8bfb4314fca3b1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PRKCI PAX8 CLMN

1.16e-06193435f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PRKCI PAX8 CLMN

1.16e-0619343542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 TANC2 SOX9 CLMN CEACAM1

1.16e-0619343522ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PRKCI PAX8 CLMN

1.19e-06194435e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

THSD4 TANC2 HOXB3 PAX8 CLMN

1.25e-0619643504f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B THSD4 TANC2 PIP5K1B PRKCI

1.35e-061994358587bd98de7767a575088afbea07a1feb4516b9b
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

HOXB3 AGBL5 PAX8 AZGP1

2.07e-051684341bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

HOXB3 AGBL5 PAX8 AZGP1

2.07e-0516843469f534de0f9a293047bea03cb1b78551087a8df5
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AGBL5 PAX8 CLMN AZGP1

2.07e-05168434c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN TP73

2.07e-05168434100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AGBL5 PAX8 CLMN AZGP1

2.07e-0516843483b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCellNS-critical-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX9 ROBO1 ASCL3 SMAD9

2.07e-051684346a233045638cb83dab64789b996b7598c325001e
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN TP73

2.42e-051754348902c38067f025b094ca9c28c449c32a66eded1c
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN TP73

2.42e-051754346bb8fc2959583644f16b22e906af91af62a3a633
ToppCelldroplet-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN TP73

2.53e-05177434a5b54792ef948a1e1de66301a60e051250189f59
ToppCellNS-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX9 ROBO1 ASCL3 SMAD9

2.65e-0517943465a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

UNC13B TANC2 PIP5K1B TCF7L1

2.71e-05180434198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 PIP5K1B HOXB3 CLMN

2.95e-051844348fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NFE2L3 SOX9 ASCL3 AZGP1

3.01e-051854341fbdc96da0623c3935ae9d29dcb4ba9c474e5c21
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NFE2L3 SOX9 ASCL3 AZGP1

3.01e-05185434b45487daac116e3d3d65ac2b0f81d1bf7d1a1914
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TNS1 PAX8 TCF7L1

3.14e-05187434c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 LARS2 TNS1 CLMN

3.14e-051874349aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HOXB3 TNS1 TCF7L1 CEACAM1

3.41e-051914342f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.41e-051914345a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.41e-0519143455ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PRKCI PAX8

3.41e-051914342fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

UNC13B PIP5K1B PRKCI TCF7L1

3.48e-0519243406013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TANC2 HOXB3 TCF7L1

3.48e-05192434fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHD7 RC3H1 TP73 SMAD9

3.48e-05192434d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

UNC13B TANC2 PIP5K1B TCF7L1

3.55e-05193434738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.55e-0519343480e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.55e-05193434b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B TANC2 PIP5K1B TCF7L1

3.55e-05193434fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 LARS2 TNS1 CLMN

3.55e-05193434c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ROBO1 KMT2E ATXN2 ERBIN

3.55e-05193434e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B TANC2 PIP5K1B TCF7L1

3.55e-05193434f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.55e-05193434263d185af6ed80e639f864e4966268e0862c61dc
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AGBL5 ASCL3 AZGP1 CEACAM1

3.63e-05194434ea5b7727ffef6cb454c501979a51bc1d4108d0e4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.70e-05195434938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 HOXB3 PAX8 CLMN

3.70e-05195434d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 TANC2 PIP5K1B SIK3

3.77e-05196434ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARS2 ERBIN RC3H1 HNRNPL

3.77e-05196434151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 TNS1 KIF21A TP73

3.77e-05196434d4df86ce289835e76763213641989fde77935a16
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 TANC2 ERBIN CLMN

3.85e-051974345bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX9 PIP5K1B TMEM214 AZGP1

3.85e-0519743492a66e3b5ddc3d55527c31e0d9cff15c2203ecfc
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B THSD4 TANC2 SIK3

3.93e-051984341996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B TANC2 PIP5K1B TCF7L1

3.93e-051984342e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B TANC2 PIP5K1B TCF7L1

3.93e-05198434f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B THSD4 PIP5K1B PRKCI

4.00e-051994345f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B THSD4 PIP5K1B PRKCI

4.00e-05199434725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B THSD4 PIP5K1B PRKCI

4.00e-051994345cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

HOXB3 TNS1 PAX8 CLMN

4.08e-052004341f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX9 PIP5K1B AZGP1 CEACAM1

4.08e-05200434a3e044468de437948b63c517e0a4773cc247c906
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 CLMN AZGP1 CEACAM1

4.08e-05200434d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 PIP5K1B AZGP1 CEACAM1

4.08e-052004340eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KMT2E ATXN2 CEACAM1

2.99e-04135433b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellremission-multiplets|World / disease stage, cell group and cell class

IGSF10 TNS1 CEACAM1

3.46e-04142433286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

THSD4 IGSF10 CEACAM1

3.53e-041434334622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

THSD4 IGSF10 CEACAM1

3.53e-041434339836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 SOX9 AGBL5

3.53e-04143433b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B SMAD9

3.91e-04148433f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B SMAD9

3.91e-041484334b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B SMAD9

3.91e-0414843355826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCellremission-multiplets|remission / disease stage, cell group and cell class

IGSF10 TNS1 CEACAM1

3.99e-04149433e9974260a5f2999b363f306cae005698c912893a
ToppCellGoblet|World / Class top

SOX9 AZGP1 CEACAM1

4.64e-04157433b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

UNC13B PIP5K1B PRKCI

4.64e-0415743331d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX9 CLMN AZGP1

5.00e-04161433f5df8c6a340d5026726804b103e32137f363ca40
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

CHD7 KMT2E ASCL3

5.09e-0416243391ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXB3 CHD7 KIF21A

5.18e-0416343399cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXB3 CHD7 KIF21A

5.18e-04163433510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 AZGP1 CEACAM1

5.18e-04163433d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B TCF7L1

5.27e-04164433f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B CLMN

5.37e-04165433e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B CLMN

5.37e-04165433b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellClub-club-16|World / Class top

KIF21A CEACAM1 SMAD9

5.37e-04165433684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PIP5K1B CLMN

5.37e-04165433d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC13B CENPT TCF7L1

5.56e-04167433f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC13B CENPT TCF7L1

5.56e-041674335fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 CLMN AZGP1

5.66e-041684338072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B THSD4 NFE2L3

5.66e-0416843306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B THSD4 NFE2L3

5.66e-041684331002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX9 CLMN AZGP1

5.75e-0416943305e12524d68d409fed386ffad233305683b4575b
ToppCelldroplet-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN

5.75e-0416943353690d6f9712b54aa99a0408aae930d64ae478e5
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

NFE2L3 TP73 CEACAM1

5.85e-0417043361f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SOX9 LARS2 CEACAM1

5.85e-04170433aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN

5.95e-041714335447b78148f7bccb727e2fc108589b2af02a5d31
ToppCelldroplet-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN

5.95e-0417143392ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 TNS1 CLMN

6.06e-04172433a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MALT1 IFT80 BATF

6.06e-04172433d824e46c8040b0bb9235f9b8a2b35386b303caa0
Diseasefree cholesterol to total lipids in medium VLDL percentage

NFE2L3 SIK3 LPAL2 ATXN2

1.46e-0657434EFO_0022284
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

NFE2L3 SIK3 LPAL2 ATXN2

1.56e-05103434EFO_0008595, EFO_0020944
DiseaseLung Neoplasms

SOX9 ROBO1 AZGP1 TP73 CEACAM1

4.10e-05265435C0024121
DiseaseMalignant neoplasm of lung

SOX9 ROBO1 AZGP1 TP73 CEACAM1

4.17e-05266435C0242379
Diseasecholesterol to total lipids in small HDL percentage

NFE2L3 SIK3 LPAL2

5.72e-0551433EFO_0022240
Diseasecholesterol to total lipids in small VLDL percentage

NFE2L3 SIK3 LPAL2

5.72e-0551433EFO_0022242
Diseasecholesteryl esters to total lipids in very large VLDL percentage

NFE2L3 SIK3 LPAL2

6.42e-0553433EFO_0022258
Diseasecholesterol to total lipids in very large VLDL percentage

NFE2L3 SIK3 LPAL2

6.79e-0554433EFO_0022244
Diseaseprostate cancer (is_marker_for)

KMT2E AZGP1 TP73 SMAD9

7.90e-05156434DOID:10283 (is_marker_for)
Diseasetriglycerides to total lipids in small VLDL percentage

NFE2L3 SIK3 LPAL2

8.41e-0558433EFO_0022338
Diseasetriglycerides to total lipids in medium VLDL percentage

NFE2L3 SIK3 LPAL2

1.08e-0463433EFO_0022335
Diseaselung cancer (is_implicated_in)

SOX9 HNRNPL TP73

1.74e-0474433DOID:1324 (is_implicated_in)
Diseasefree cholesterol to total lipids in small VLDL percentage

NFE2L3 SIK3 LPAL2

1.81e-0475433EFO_0022287
Diseaseurate measurement, bone density

THSD4 ROBO1 ERBIN PSMG3-AS1 TCF7L1 RC3H1

2.62e-04619436EFO_0003923, EFO_0004531
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

NFE2L3 SIK3 LPAL2 ATXN2

4.04e-04239434EFO_0008317, EFO_0020945
Diseasebasophil count, eosinophil count

CHD7 SIK3 ATXN2 BATF

4.17e-04241434EFO_0004842, EFO_0005090
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

NFE2L3 SIK3 LPAL2 ATXN2

4.30e-04243434EFO_0004612, EFO_0020944
Diseaseblood urea nitrogen measurement

ROBO1 PIP5K1B ATXN2 PAX8 TCF7L1

4.92e-04452435EFO_0004741
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

NFE2L3 SIK3 LPAL2

5.58e-04110433EFO_0008317, EFO_0008591, EFO_0008596
Diseasecortical surface area measurement

THSD4 TANC2 ROBO1 CHD7 AGBL5 ATXN2 TNS1 TCF7L1

6.37e-041345438EFO_0010736
DiseaseCarcinoma, Granular Cell

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0205644
DiseaseAdenocarcinoma, Tubular

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0205645
DiseaseAdenocarcinoma, Oxyphilic

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0205642
DiseaseCarcinoma, Cribriform

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0205643
DiseaseAdenocarcinoma, Basal Cell

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0205641
DiseaseAdenocarcinoma

ROBO1 AZGP1 CEACAM1

6.51e-04116433C0001418
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

NFE2L3 SIK3 LPAL2 ATXN2

6.94e-04276434EFO_0004612, EFO_0020943
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

NFE2L3 SIK3 LPAL2 ATXN2

8.45e-04291434EFO_0008317, EFO_0020946
Diseasecervical cancer (is_implicated_in)

KMT2E TP73

8.79e-0430432DOID:4362 (is_implicated_in)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

NFE2L3 SIK3 LPAL2 ATXN2

9.81e-04303434EFO_0004612, EFO_0020945
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

NFE2L3 SIK3 LPAL2 ATXN2

1.03e-03307434EFO_0004612, EFO_0020946
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

NFE2L3 LPAL2

1.13e-0334432EFO_0008317, EFO_0008596, EFO_0020944
Diseasechylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

SIK3 LPAL2

1.13e-0334432EFO_0008317, EFO_0008596, EFO_0020947
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

NFE2L3 SIK3 ATXN2

1.22e-03144433EFO_0004611, EFO_0020943
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

NFE2L3 LPAL2 ATXN2

1.37e-03150433EFO_0004611, EFO_0020947
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

NFE2L3 SIK3 LPAL2

1.45e-03153433EFO_0004611, EFO_0020946
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

NFE2L3 SIK3 LPAL2

1.45e-03153433EFO_0004611, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
PENHPTHSSPLDTIY

AGBL5

176

Q8NDL9
PQANYSQIHHPPQAS

ERBIN

1266

Q96RT1
NGLASPHSQYHTPPV

CHD7

96

Q9P2D1
SPYSPHQNIPSQGHF

RC3H1

926

Q5TC82
THQTYPVVADPHSPF

PAX8

291

Q06710
DHAQTVIPYNPSSHE

PRKCI

211

P41743
SSDSSAKPSVYPHPH

PSMG3-AS1

246

Q96PY0
YHSHPGNPSNVTPAD

MALT1

761

Q9UDY8
QQYAHPNATLHPHTP

ATXN2

1131

Q99700
FTIHPSHVQPAYTNP

ATXN2

1226

Q99700
PSEGSNLTPAHHYPD

PIP5K1B

66

O14986
HNHTYHLQPTAPEST

NFE2L3

496

Q9Y4A8
SPYRPHHSQSPQVGT

KMT2E

1476

Q8IZD2
TPEHAASVPTHSPYA

TP73

86

O15350
PSNTDYPGPHHFEVT

TP73

116

O15350
TFPSDPHTAAHSQFP

IGSF10

981

Q6WRI0
PLYNSQPHEHPITSV

IFT80

221

Q9P2H3
PSVSNHTQDHSNDPP

CEACAM1

471

P13688
QSAPHHFPDSFQATP

COLCA2

11

A8K830
PSPPEVVYSAHAFHQ

BATF

101

Q16520
SPNVYHSLPCTPHTG

CENPT

251

Q96BT3
TYTDLSSHHAPPPQG

HOXB3

406

P14651
FHVHPEAPVSSPYSE

ASCL3

36

Q9NQ33
NYDDPHKTPASPVVH

HNRNPL

91

P14866
SPPHLTDQPSAYSHT

CT62

11

P0C5K7
SLSYPQHHVGNSSPT

RBM7

96

Q9Y580
PHNPHSPFNTAVADY

LARS2

536

Q15031
TPHQHSRTPEKYPND

LPAL2

56

Q16609
YSNSHGPSDSNPPHK

NBPF7P

231

P0C2Y1
VSQASSPTPPHGYAH

SIK3

1071

Q9Y2K2
SPALSPTHQNSHYRP

TANC2

1486

Q9HCD6
QLSPSHYSEQQQHSP

SOX9

401

P48436
AAPHPLQSYATNHHP

PRR12

51

Q9ULL5
QHSVDTPPLPYHATE

SMAD9

221

O15198
YTVNHETSHPPPSKV

CLMN

336

Q96JQ2
AYGQSHRSPHPSTEP

SPEM2

356

Q0P670
SAQAQTHSPPHTPEY

SPEM3

301

A0A1B0GUW6
THSPPHTPEYTHSQA

SPEM3

306

A0A1B0GUW6
TYSNDHFSPGSPPTH

TCF7L1

196

Q9HCS4
TVSPTHNFEPPHYDG

KIF21A

1531

Q7Z4S6
PQPVTTSHYAHDPSG

TNS1

601

Q9HBL0
PLSEPTLSQHTHDYP

TMEM214

156

Q6NUQ4
PPYHTASQPNASVHQ

UNC13B

201

O14795
AHYTPLTHPVSAPSS

TBXT

381

O15178
AHPPPHSNSEEYNIS

ROBO1

1191

Q9Y6N7
DQAHPPIHPTKYTNN

TOP3A

411

Q13472
PPQDTAPYSCHVQHS

AZGP1

271

P25311
SARHGYSSPAHQVPQ

THSD4

206

Q6ZMP0