Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside binding	POLR3B POLR1B	1.69e-05	3	48	2	GO:0032549
GeneOntologyMolecularFunction	DNA/RNA hybrid binding	POLR3B POLR1B	5.63e-05	5	48	2	GO:0071667
GeneOntologyMolecularFunction	nucleoside binding	POLR3B POLR1B	3.07e-04	11	48	2	GO:0001882
GeneOntologyMolecularFunction	Arp2/3 complex binding	GMFG GMFB	6.65e-04	16	48	2	GO:0071933
GeneOntologyBiologicalProcess	actin filament debranching	GMFG GMFB	5.53e-06	2	49	2	GO:0071846
Domain	GMF	GMFG GMFB	6.20e-06	2	47	2	IPR011171
Domain	-	POLR3B POLR1B	1.86e-05	3	47	2	2.40.270.10
Domain	DNA-dir_RNA_pol_su2	POLR3B POLR1B	1.86e-05	3	47	2	IPR015712
Domain	RNA_pol_RPB2_OB-fold	POLR3B POLR1B	1.86e-05	3	47	2	IPR014724
Domain	RNA_pol_bsu_CS	POLR3B POLR1B	1.86e-05	3	47	2	IPR007121
Domain	DNA-dir_RNA_pol_su2_6	POLR3B POLR1B	1.86e-05	3	47	2	IPR007120
Domain	RNA_pol_Rpb2_6	POLR3B POLR1B	1.86e-05	3	47	2	PF00562
Domain	RNA_pol_Rpb2_7	POLR3B POLR1B	1.86e-05	3	47	2	PF04560
Domain	RNA_pol_Rpb2_2	POLR3B POLR1B	1.86e-05	3	47	2	PF04561
Domain	RNA_pol_Rpb2_5	POLR3B POLR1B	1.86e-05	3	47	2	PF04567
Domain	RNA_pol_Rpb2_1	POLR3B POLR1B	1.86e-05	3	47	2	PF04563
Domain	RNA_pol_Rpb2_3	POLR3B POLR1B	1.86e-05	3	47	2	PF04565
Domain	RNA_pol_Rpb2_5	POLR3B POLR1B	1.86e-05	3	47	2	IPR007647
Domain	RNA_pol_Rpb2_3	POLR3B POLR1B	1.86e-05	3	47	2	IPR007645
Domain	RNA_pol_bsu_protrusion	POLR3B POLR1B	1.86e-05	3	47	2	IPR007644
Domain	RNA_pol_Rpb2_2	POLR3B POLR1B	1.86e-05	3	47	2	IPR007642
Domain	RNA_pol_Rpb2_7	POLR3B POLR1B	1.86e-05	3	47	2	IPR007641
Domain	-	POLR3B POLR1B	1.86e-05	3	47	2	2.40.50.150
Domain	RNA_POL_BETA	POLR3B POLR1B	1.86e-05	3	47	2	PS01166
Domain	-	POLR3B POLR1B	1.86e-05	3	47	2	3.90.1110.10
Domain	Spectrin_repeat	DSP SPTBN1 SYNE2	5.21e-05	29	47	3	IPR002017
Domain	Spectrin/alpha-actinin	DSP SPTBN1 SYNE2	7.04e-05	32	47	3	IPR018159
Domain	SPEC	DSP SPTBN1 SYNE2	7.04e-05	32	47	3	SM00150
Domain	ADF	GMFG GMFB	2.75e-04	10	47	2	SM00102
Domain	Cofilin_ADF	GMFG GMFB	2.75e-04	10	47	2	PF00241
Domain	ADF_H	GMFG GMFB	2.75e-04	10	47	2	PS51263
Domain	ADF-H	GMFG GMFB	2.75e-04	10	47	2	IPR002108
Domain	Actinin_actin-bd_CS	SPTBN1 SYNE2	1.52e-03	23	47	2	IPR001589
Domain	NACHT	NAIP NLRP5	1.52e-03	23	47	2	PS50837
Domain	NACHT_NTPase	NAIP NLRP5	1.52e-03	23	47	2	IPR007111
Domain	Spectrin	SPTBN1 SYNE2	1.52e-03	23	47	2	PF00435
Domain	ACTININ_2	SPTBN1 SYNE2	1.52e-03	23	47	2	PS00020
Domain	ACTININ_1	SPTBN1 SYNE2	1.52e-03	23	47	2	PS00019
Domain	ADF-H/Gelsolin-like_dom	GMFG GMFB	1.65e-03	24	47	2	IPR029006
Domain	-	GMFG GMFB	1.65e-03	24	47	2	3.40.20.10
Domain	Arm	PKP1 CTNNB1	2.75e-03	31	47	2	PF00514
Domain	BROMODOMAIN_1	TRIM66 CECR2	3.90e-03	37	47	2	PS00633
Domain	EGF	ZAN LTBP1 CUBN	3.92e-03	126	47	3	PF00008
Domain	Bromodomain	TRIM66 CECR2	4.11e-03	38	47	2	PF00439
Domain	ARM_REPEAT	PKP1 CTNNB1	4.55e-03	40	47	2	PS50176
Domain	ARM	PKP1 CTNNB1	4.55e-03	40	47	2	SM00185
Domain	BROMODOMAIN_2	TRIM66 CECR2	4.77e-03	41	47	2	PS50014
Domain	BROMO	TRIM66 CECR2	5.01e-03	42	47	2	SM00297
Domain	Bromodomain	TRIM66 CECR2	5.01e-03	42	47	2	IPR001487
Domain	-	TRIM66 CECR2	5.01e-03	42	47	2	1.20.920.10
Domain	Armadillo	PKP1 CTNNB1	6.23e-03	47	47	2	IPR000225
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	DSP PKP1 CTNNB1	1.81e-06	10	36	3	MM14956
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	DSP PKP1 CTNNB1	2.49e-06	11	36	3	M9990
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	FZD4 DSP PKP1 CTNNB1 EZH2	5.17e-05	161	36	5	M39770
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	DSP PKP1 CTNNB1	1.12e-04	37	36	3	MM14488
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	DSP PKP1 CTNNB1	1.21e-04	38	36	3	M495
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	DSP PKP1 CTNNB1	2.60e-04	49	36	3	MM15448
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	DSP PKP1 CTNNB1	3.10e-04	52	36	3	M2341
Pubmed	Antagonistic Regulation of Intercellular Cohesion by Plakophilins 1 and 3.	DSP PKP1 CTNNB1	5.24e-08	6	49	3	27375112
Pubmed	A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.	DSP PKP1 CTNNB1	9.16e-08	7	49	3	17535849
Pubmed	Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.	DSP PKP1 CTNNB1	4.30e-07	11	49	3	11790773
Pubmed	Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease.	EOMES SYNE2 CTNNB1	5.73e-07	12	49	3	29868845
Pubmed	Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.	DSP PKP1 CTNNB1	1.18e-06	15	49	3	9847250
Pubmed	p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.	DSP PKP1 CTNNB1	1.18e-06	15	49	3	23108156
Pubmed	Desmocollin 3 is required for pre-implantation development of the mouse embryo.	DSP PKP1 CTNNB1	1.45e-06	16	49	3	16418220
Pubmed	Coronary veins determine the pattern of sympathetic innervation in the developing heart.	GMFG GMFB CTNNB1	1.45e-06	16	49	3	23462468
Pubmed	RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.	DSP PKP1 CTNNB1	1.45e-06	16	49	3	30689641
Pubmed	Desmoplakin is essential in epidermal sheet formation.	DSP PKP1 CTNNB1	1.76e-06	17	49	3	11781569
Pubmed	FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4.	FZD4 FOXF1	1.94e-06	2	49	2	38589650
Pubmed	Novel truncating mutations in PKP1 and DSP cause similar skin phenotypes in two Brazilian families.	DSP PKP1	1.94e-06	2	49	2	19016709
Pubmed	Genetic inactivation of β-catenin is salubrious, whereas its activation is deleterious in desmoplakin cardiomyopathy.	DSP CTNNB1	1.94e-06	2	49	2	37625794
Pubmed	GMF is an evolutionarily developed Adf/cofilin-super family protein involved in the Arp2/3 complex-mediated organization of the actin cytoskeleton.	GMFG GMFB	1.94e-06	2	49	2	20517925
Pubmed	Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma.	CTNNB1 EZH2	1.94e-06	2	49	2	27385092
Pubmed	Nesprins are mechanotransducers that discriminate epithelial-mesenchymal transition programs.	SYNE2 CTNNB1	1.94e-06	2	49	2	32790861
Pubmed	Isolation of novel human cDNA (hGMF-gamma) homologous to Glia Maturation Factor-beta gene.	GMFG GMFB	1.94e-06	2	49	2	9545571
Pubmed	beta-Catenin and plakoglobin N- and C-tails determine ligand specificity.	DSP CTNNB1	1.94e-06	2	49	2	15381698
Pubmed	N-terminal nesprin-2 variants regulate β-catenin signalling.	SYNE2 CTNNB1	1.94e-06	2	49	2	27321956
Pubmed	Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia.	CTNNB1 EZH2	1.94e-06	2	49	2	19661437
Pubmed	Beta-catenin signaling negatively regulates intermediate progenitor population numbers in the developing cortex.	EOMES CTNNB1	1.94e-06	2	49	2	20811503
Pubmed	Identification and isolation of a full-length clone of mouse GMFB (Gmfb), a putative intracellular kinase regulator, differentially expressed in telencephalon.	GMFG GMFB	1.94e-06	2	49	2	11435704
Pubmed	Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.	EOMES CTNNB1 CPS1	2.95e-06	20	49	3	26033091
Pubmed	Phorbol ester stimulates rapid intracellular phosphorylation of glia maturation factor.	GMFG GMFB	5.83e-06	3	49	2	7598724
Pubmed	miR-98 inhibits hepatocellular carcinoma cell proliferation via targeting EZH2 and suppressing Wnt/β-catenin signaling pathway.	CTNNB1 EZH2	5.83e-06	3	49	2	27890434
Pubmed	Aberrant Activation of β-Catenin Signaling Drives Glioma Tumorigenesis via USP1-Mediated Stabilization of EZH2.	CTNNB1 EZH2	5.83e-06	3	49	2	30425057
Pubmed	In vitro enhancement of p38 mitogen-activated protein kinase activity by phosphorylated glia maturation factor.	GMFG GMFB	5.83e-06	3	49	2	8798479
Pubmed	PI3Kβ-regulated β-catenin mediates EZH2 removal from promoters controlling primed human ESC stemness and primitive streak gene expression.	CTNNB1 EZH2	5.83e-06	3	49	2	36179694
Pubmed	EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling.	CTNNB1 EZH2	5.83e-06	3	49	2	21215703
Pubmed	Low-Dose Tamoxifen Induces Significant Bone Formation in Mice.	CTNNB1 EZH2	5.83e-06	3	49	2	33778320
Pubmed	Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy.	DSP CTNNB1	5.83e-06	3	49	2	16823493
Pubmed	Downregulation of miR-3127-5p promotes epithelial-mesenchymal transition via FZD4 regulation of Wnt/β-catenin signaling in non-small-cell lung cancer.	FZD4 CTNNB1	5.83e-06	3	49	2	29566281
Pubmed	Plakoglobin is required for effective intermediate filament anchorage to desmosomes.	DSP PKP1	5.83e-06	3	49	2	18496566
Pubmed	Growth Retardation, Loss of Desmosomal Adhesion, and Impaired Tight Junction Function Identify a Unique Role of Plakophilin 1 In Vivo.	DSP PKP1	5.83e-06	3	49	2	27033150
Pubmed	lnc-β-Catm elicits EZH2-dependent β-catenin stabilization and sustains liver CSC self-renewal.	CTNNB1 EZH2	5.83e-06	3	49	2	27239797
Pubmed	Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.	DSP PKP1 CTNNB1	1.04e-05	30	49	3	34905516
Pubmed	Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation.	FZD4 CTNNB1	1.16e-05	4	49	2	17428233
Pubmed	Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.	DSP CTNNB1	1.16e-05	4	49	2	8858175
Pubmed	Dual-Regulated Mechanism of EZH2 and KDM6A on SALL4 Modulates Tumor Progression via Wnt/β-Catenin Pathway in Gastric Cancer.	CTNNB1 EZH2	1.16e-05	4	49	2	36877334
Pubmed	Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.	CTNNB1 CPS1	1.16e-05	4	49	2	29426940
Pubmed	EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma.	CTNNB1 EZH2	1.16e-05	4	49	2	27092879
Pubmed	Insulin signaling via Akt2 switches plakophilin 1 function from stabilizing cell adhesion to promoting cell proliferation.	DSP PKP1	1.16e-05	4	49	2	23444369
Pubmed	The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells.	EOMES EZH2	1.16e-05	4	49	2	24238339
Pubmed	In vitro inhibition of MAP kinase (ERK1/ERK2) activity by phosphorylated glia maturation factor (GMF).	GMFG GMFB	1.16e-05	4	49	2	8639570
Pubmed	Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites.	CTNNB1 EZH2	1.16e-05	4	49	2	29445149
Pubmed	Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, β-catenin and EZH2.	CTNNB1 EZH2	1.16e-05	4	49	2	24608043
Pubmed	The Ki67+ proliferation index correlates with increased cellular retinol-binding protein-1 and the coordinated loss of plakophilin-1 and desmoplakin during progression of cervical squamous lesions.	DSP PKP1	1.16e-05	4	49	2	17593084
Pubmed	Genome-wide occupancy links Hoxa2 to Wnt-β-catenin signaling in mouse embryonic development.	FZD4 CTNNB1	1.16e-05	4	49	2	22223247
Pubmed	Mouse embryonic submandibular gland epithelium loses its tissue integrity during early branching morphogenesis.	DSP CTNNB1	1.16e-05	4	49	2	8950514
Pubmed	Defining the interactions between intermediate filaments and desmosomes.	DSP PKP1	1.94e-05	5	49	2	9606214
Pubmed	Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.	CTNNB1 EZH2	1.94e-05	5	49	2	17502350
Pubmed	Plakophilin-1, a Novel Wnt Signaling Regulator, Is Critical for Tooth Development and Ameloblast Differentiation.	PKP1 CTNNB1	1.94e-05	5	49	2	27015268
Pubmed	The fate of desmosomal proteins in apoptotic cells.	DSP PKP1	1.94e-05	5	49	2	11500511
Pubmed	The desmoglein-specific cytoplasmic region is intrinsically disordered in solution and interacts with multiple desmosomal protein partners.	DSP PKP1	1.94e-05	5	49	2	19136012
Pubmed	Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling.	FZD4 CTNNB1	1.94e-05	5	49	2	25373781
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZBTB2 DSP ZNF268 FBXO42 PKP1 CTNNB1 CPS1 FOXF1	2.43e-05	857	49	8	25609649
Pubmed	Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers.	FZD4 CTNNB1	2.91e-05	6	49	2	31066677
Pubmed	Katanin p80 regulates human cortical development by limiting centriole and cilia number.	EOMES CTNNB1	2.91e-05	6	49	2	25521379
Pubmed	PAF and EZH2 induce Wnt/β-catenin signaling hyperactivation.	CTNNB1 EZH2	2.91e-05	6	49	2	24055345
Pubmed	In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis.	EOMES CTNNB1	2.91e-05	6	49	2	15198985
Pubmed	MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways.	CTNNB1 FOXF1	2.91e-05	6	49	2	28131747
Pubmed	The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility.	DSP CTNNB1	2.91e-05	6	49	2	12975353
Pubmed	The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine.	FZD4 CTNNB1	4.07e-05	7	49	2	19001373
Pubmed	Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures.	FZD4 CTNNB1	4.07e-05	7	49	2	30932813
Pubmed	Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.	DSP PKP1	4.07e-05	7	49	2	28507225
Pubmed	Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation.	CTNNB1 EZH2	4.07e-05	7	49	2	24469040
Pubmed	Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.	DSP CTNNB1	4.07e-05	7	49	2	15479741
Pubmed	Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis.	CACNA1A CTNNB1	4.07e-05	7	49	2	37365500
Pubmed	Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex.	EOMES CTNNB1	4.07e-05	7	49	2	23972596
Pubmed	Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation.	DSP CTNNB1	5.42e-05	8	49	2	10801826
Pubmed	PRC2 Is Dispensable in Vivo for β-Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme.	CTNNB1 EZH2	5.42e-05	8	49	2	29223978
Pubmed	Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1.	EOMES CTNNB1	5.42e-05	8	49	2	22095214
Pubmed	Catenin α 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/β-catenin signaling.	FZD4 CTNNB1	5.42e-05	8	49	2	33497368
Pubmed	The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice.	DSP CTNNB1	6.96e-05	9	49	2	18703497
Pubmed	EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells.	CTNNB1 EZH2	6.96e-05	9	49	2	31130994
Pubmed	Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development.	EOMES CTNNB1	6.96e-05	9	49	2	24832538
Pubmed	Transgenic increase of Wnt7b in neural progenitor cells decreases expression of T-domain transcription factors and impairs neuronal differentiation.	EOMES CTNNB1	6.96e-05	9	49	2	24953933
Pubmed	Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation.	CTNNB1 FOXF1	6.96e-05	9	49	2	39052671
Pubmed	Scratch2 modulates neurogenesis and cell migration through antagonism of bHLH proteins in the developing neocortex.	EOMES CTNNB1	6.96e-05	9	49	2	23180754
Pubmed	Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain.	EOMES CTNNB1	6.96e-05	9	49	2	26921468
Pubmed	Alix is required during development for normal growth of the mouse brain.	EOMES CTNNB1	6.96e-05	9	49	2	28322231
Pubmed	A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.	FZD4 CTNNB1	6.96e-05	9	49	2	9707618
Pubmed	Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.	SPTBN1 CTNNB1 EZH2	7.29e-05	57	49	3	21122108
Pubmed	Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.	DSP PKP1	8.69e-05	10	49	2	10852826
Pubmed	Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development†.	EOMES CTNNB1	8.69e-05	10	49	2	32186707
Pubmed	Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.	DSP CTNNB1	8.69e-05	10	49	2	12724416
Pubmed	RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells.	EOMES CTNNB1	8.69e-05	10	49	2	20103535
Pubmed	Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors.	EOMES CTNNB1	8.69e-05	10	49	2	17706960
Pubmed	Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex.	EOMES CTNNB1	8.69e-05	10	49	2	20215343
Pubmed	Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2S252W/+ ) mouse model.	FZD4 CTNNB1	8.69e-05	10	49	2	32822074
Pubmed	USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.	SPTBN1 CPS1	8.69e-05	10	49	2	36653359
Pubmed	Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.	FZD4 CTNNB1	8.69e-05	10	49	2	17532316
Pubmed	Norrie disease protein is essential for cochlear hair cell maturation.	FZD4 CTNNB1	8.69e-05	10	49	2	34544869
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	EOMES ZBTB2 ZBTB48	9.83e-05	63	49	3	34351428
Pubmed	Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.	FZD4 CTNNB1	1.06e-04	11	49	2	24860427
Pubmed	Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice.	EOMES CTNNB1	1.06e-04	11	49	2	37553426
Pubmed	Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause.	EOMES CTNNB1	1.06e-04	11	49	2	33127892
Pubmed	Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.	CTNNB1 CPS1	1.06e-04	11	49	2	20084116
Pubmed	Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.	KDM4D EZH2	1.06e-04	11	49	2	19144645
Pubmed	FASN-dependent de novo lipogenesis is required for brain development.	EOMES CTNNB1	1.06e-04	11	49	2	34996870
GeneFamily	NLR family	NAIP NLRP5	1.00e-03	25	34	2	666
GeneFamily	RNA polymerase subunits	POLR3B POLR1B	1.35e-03	29	34	2	726
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PKP1 CTNNB1	2.95e-03	43	34	2	409
Coexpression	PGF_UP.V1_UP	ZNF268 SYNE2 GMFB CPD LTBP1	2.27e-05	190	47	5	M2674
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN	CACNA1A DSP ZNFX1 EZH2 FOXF1	2.45e-05	193	47	5	M4284
Coexpression	GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_UP	CACNA1A CECR2 CUBN ADAMTSL3 MFSD12	2.71e-05	197	47	5	M3555
Coexpression	TRAVAGLINI_LUNG_PERICYTE_CELL	GMFG ADAMTSL3 PREX2 FOXF1	5.24e-05	114	47	4	M41678
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2K DSP SPTBN1 SYNE2 CTNNB1 SLC4A4	5.72e-08	191	48	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD4 DSP SYNE2 ADAMTSL3 FOXF1	1.22e-06	174	48	5	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD4 DSP SYNE2 ADAMTSL3 FOXF1	1.22e-06	174	48	5	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	FZD4 SPTBN1 SYNE2 PREX2 FOXF1	1.48e-06	181	48	5	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	P07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FZD4 GMFG CTNNB1 PREX2 FOXF1	1.79e-06	188	48	5	ee8ff134a639deca2bb3027c4d3291f48c12d171
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2K DSP SPTBN1 SYNE2 SLC4A4	1.93e-06	191	48	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2K DSP SPTBN1 SYNE2 SLC4A4	1.93e-06	191	48	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	IPF-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	FZD4 SPTBN1 PKP1 PREX2 FOXF1	2.03e-06	193	48	5	d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN1 LTBP1 CSGALNACT1 PREX2 FOXF1	2.19e-06	196	48	5	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	FZD4 SYNE2 CSGALNACT1 PREX2 FOXF1	2.30e-06	198	48	5	531b0f88c95f813e3914c96749f591e80ca321d0
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	FZD4 SPTBN1 SYNE2 CSGALNACT1 PREX2	2.42e-06	200	48	5	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	FZD4 SPTBN1 SYNE2 CSGALNACT1 PREX2	2.42e-06	200	48	5	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	EOMES ZBTB48 CUBN PREX2	2.11e-05	151	48	4	4533bccc996395f74b16af939ce79b6fe253c073
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	EOMES ZBTB48 CUBN PREX2	2.11e-05	151	48	4	edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|Lung / Manually curated celltypes from each tissue	EOMES SYNE2 HSFX3 SLC4A4	2.46e-05	157	48	4	af6eb2214340847bbab7cb209ea27cdc83b62a27
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	CACNA1A DSP PKP1 PGBD5	2.53e-05	158	48	4	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	Club-club-1\|World / Class top	KDM4D FBXO42 ZNFX1	2.72e-05	54	48	3	48f80b20b1c4995a0f7084d31666781dce4009a9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A ZAN CUBN NLRP5	3.14e-05	167	48	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	EOMES KDM4D SYNE2 SLC4A4	3.14e-05	167	48	4	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	CSGALNACT1 PREX2 HEPH FOXF1	3.76e-05	175	48	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FZD4 SPTBN1 SYNE2 FOXF1	4.29e-05	181	48	4	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FZD4 GMFG CSGALNACT1 FOXF1	4.39e-05	182	48	4	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	CACNA1A BMP2K DSP ZNFX1	4.48e-05	183	48	4	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	4.67e-05	185	48	4	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PKP1 CUBN CSGALNACT1 FOXF1	4.77e-05	186	48	4	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	PKP1 CUBN CSGALNACT1 FOXF1	4.77e-05	186	48	4	c3449e54454009973818fc1101933c6f0168258c
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DSP ADAMTSL3 PREX2 FOXF1	4.77e-05	186	48	4	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CECR2 SLC4A4 PREX2 HEPH	4.87e-05	187	48	4	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CECR2 SLC4A4 PREX2 HEPH	4.87e-05	187	48	4	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CECR2 SLC4A4 PREX2 HEPH	4.87e-05	187	48	4	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	FZD4 SPTBN1 PKP1 FOXF1	4.87e-05	187	48	4	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EOMES SYNE2 GMFB SLC4A4	4.87e-05	187	48	4	b426a67b5669019115b58295ce7d304beeb75825
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	4.87e-05	187	48	4	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	FZD4 SPTBN1 NAIP FOXF1	4.98e-05	188	48	4	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD4 SPTBN1 PREX2 FOXF1	5.08e-05	189	48	4	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	SPTBN1 PKP1 PREX2 FOXF1	5.18e-05	190	48	4	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPTBN1 CPD CTNNB1 PREX2	5.18e-05	190	48	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FZD4 SPTBN1 PREX2 FOXF1	5.18e-05	190	48	4	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EOMES CACNA1A GMFB SLC4A4	5.18e-05	190	48	4	600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.29e-05	191	48	4	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LTBP1 SLC4A4 HEPH FOXF1	5.40e-05	192	48	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD4 SPTBN1 CPD FOXF1	5.40e-05	192	48	4	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	E15.5-Endothelial\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FZD4 GMFG PREX2 FOXF1	5.40e-05	192	48	4	88cc7f14d031a0613d032eb01c93e88c72d3938f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EOMES CACNA1A SYNE2 GMFB	5.40e-05	192	48	4	3b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD4 SPTBN1 PREX2 FOXF1	5.51e-05	193	48	4	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD4 DSP PREX2 FOXF1	5.51e-05	193	48	4	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)\|Adult / Lineage, Cell type, age group and donor	FZD4 SPTBN1 PKP1 FOXF1	5.51e-05	193	48	4	39c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.51e-05	193	48	4	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FZD4 SPTBN1 PKP1 FOXF1	5.51e-05	193	48	4	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FZD4 CSGALNACT1 PREX2 FOXF1	5.51e-05	193	48	4	ff6e6b825d6c88148216c601580be3c28851ab5c
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.51e-05	193	48	4	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD4 SPTBN1 PREX2 FOXF1	5.51e-05	193	48	4	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	SYNE2 GMFG ADAMTSL3 PREX2	5.62e-05	194	48	4	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	Endothelial-A-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FZD4 CSGALNACT1 PREX2 FOXF1	5.62e-05	194	48	4	e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCell	COPD-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.62e-05	194	48	4	68705a6eca947c5b42b943d5224a7aef2a744007
ToppCell	IPF-Endothelial-VE_Capillary_B\|IPF / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.62e-05	194	48	4	169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCell	droplet-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SPTBN1 SYNE2 PKP1	5.62e-05	194	48	4	592e8c4b73ba424a52305ac411ea9c0a2dc44467
ToppCell	COPD-Endothelial-VE_Capillary_B\|COPD / Disease state, Lineage and Cell class	FZD4 SPTBN1 PREX2 FOXF1	5.62e-05	194	48	4	18b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell	Endothelial\|World / shred by cell class for bronchial biopsy	FZD4 GMFG CSGALNACT1 PREX2	5.73e-05	195	48	4	f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FZD4 SPTBN1 SYNE2 FOXF1	5.85e-05	196	48	4	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD4 SPTBN1 PREX2 FOXF1	5.85e-05	196	48	4	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	FZD4 SPTBN1 PREX2 FOXF1	5.85e-05	196	48	4	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	FZD4 SPTBN1 SYNE2 FOXF1	5.85e-05	196	48	4	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	Endothelial-capillary_endothelial_cell_(Cap1)\|World / Lineage, Cell type, age group and donor	SPTBN1 CSGALNACT1 PREX2 FOXF1	5.85e-05	196	48	4	0ce3ed27d2b9276390952652c17a8d6de13add36
ToppCell	tumor_Lung-Endothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	FZD4 SPTBN1 PREX2 FOXF1	5.97e-05	197	48	4	6870b311c54a73723768276a58456620f5217d43
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	FZD4 SPTBN1 SYNE2 PREX2	5.97e-05	197	48	4	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EOMES DSP SYNE2 PKP1	5.97e-05	197	48	4	80ffafa9473f4ee7a3a792d11b5541e1c984c9f0
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	FZD4 GMFG CSGALNACT1 PREX2	5.97e-05	197	48	4	1b82979a41ef46c814c82527a585900586d71260
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD4 DSP CUBN PREX2	5.97e-05	197	48	4	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	FZD4 GMFG CSGALNACT1 PREX2	5.97e-05	197	48	4	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EOMES DSP SYNE2 PKP1	5.97e-05	197	48	4	f3dfc22ff63e6173451a0917c5aedcde793fd170
ToppCell	COVID-CD4-exh_CD4\|COVID / Condition, Cell_class and T cell subcluster	SPTBN1 SYNE2 GMFG EZH2	5.97e-05	197	48	4	39ee4b93625c994813044d8dd8854fba2bd99940
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	FZD4 SPTBN1 SYNE2 PREX2	6.20e-05	199	48	4	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FZD4 SPTBN1 CSGALNACT1 PREX2	6.20e-05	199	48	4	b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 SYNE2 GMFG PREX2	6.20e-05	199	48	4	5d976d57872a8a25a11fe8cd53b01aa21a1a519a
ToppCell	Parenchymal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FZD4 CSGALNACT1 PREX2 FOXF1	6.20e-05	199	48	4	a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD4 DSP CUBN PREX2	6.20e-05	199	48	4	c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 SYNE2 GMFG PREX2	6.20e-05	199	48	4	14e09eaa2335d4503de50250eb4258dd5b85b304
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FZD4 SPTBN1 SYNE2 CSGALNACT1	6.33e-05	200	48	4	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	2d962c9d63e9e5f1a06870e383609672e7b1738c
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Capillary\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	FZD4 SPTBN1 PKP1 FOXF1	6.33e-05	200	48	4	6c0498a5868891e8e22c03469d00669b20249b1a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTBN1 SYNE2 CSGALNACT1 PREX2	6.33e-05	200	48	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Biopsy_Other_PF-Endothelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	2989325b0e78ab42f362cfb59e34a4fce7f8e869
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SYNE2 ADAMTSL3 PREX2 FOXF1	6.33e-05	200	48	4	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DSP SPTBN1 SYNE2 PKP1	6.33e-05	200	48	4	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Parenchymal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	0e648e9eb96c83a94505d07323785a7a40997eb0
ToppCell	Parenchyma_COVID-19-Endothelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FZD4 SPTBN1 SYNE2 CSGALNACT1	6.33e-05	200	48	4	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FZD4 SPTBN1 PKP1 FOXF1	6.33e-05	200	48	4	7020045b933cb104fb99b79524cb0d4734b8636d
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SYNE2 LTBP1 CSGALNACT1 PREX2	6.33e-05	200	48	4	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE2 ADAMTSL3 PREX2 FOXF1	6.33e-05	200	48	4	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Biopsy_Other_PF-Endothelial-Endothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	40d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCell	Lung_Parenchyma-Severe-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	d9d0ffa18e5b4647966e19ad9830cbba6120677e
ToppCell	Bronchial-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPTBN1 SYNE2 CSGALNACT1 PREX2	6.33e-05	200	48	4	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FZD4 SPTBN1 PKP1 FOXF1	6.33e-05	200	48	4	e9913511a129bb3cee85e7ebf565b951dab91542
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FZD4 SPTBN1 PREX2 FOXF1	6.33e-05	200	48	4	e9d5ba140cabae11c437012d519b85f5412dcc94
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE2 ADAMTSL3 PREX2 FOXF1	6.33e-05	200	48	4	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD4 DSP SPTBN1 PREX2	6.33e-05	200	48	4	c239e6f5d23caa9a59b83e9b352b2d6a691dcb28
Disease	Persistent Fetal Circulation Syndrome	CPS1 FOXF1	2.27e-06	2	45	2	C0031190
Disease	Ectodermal dysplasia/ skin fragility syndrome	DSP PKP1	2.27e-06	2	45	2	C1858302
Disease	persistent fetal circulation syndrome (is_implicated_in)	CPS1 FOXF1	6.82e-06	3	45	2	DOID:13042 (is_implicated_in)
Disease	Exudative vitreoretinopathy 1	FZD4 CTNNB1	1.36e-05	4	45	2	C1851402
Disease	exudative vitreoretinopathy (implicated_via_orthology)	FZD4 CTNNB1	6.33e-05	8	45	2	DOID:0050535 (implicated_via_orthology)
Disease	hepatitis B (is_marker_for)	CTNNB1 PREX2	4.69e-04	21	45	2	DOID:2043 (is_marker_for)
Disease	myeloid white cell count	EOMES CD300LF SPTBN1 NAIP POLR1B CPS1 PREX2	5.04e-04	937	45	7	EFO_0007988
Disease	cholangiocarcinoma (is_implicated_in)	EZH2 PREX2	5.15e-04	22	45	2	DOID:4947 (is_implicated_in)
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 CPS1 CSGALNACT1	5.27e-04	103	45	3	EFO_0008595, EFO_0020944
Disease	ergothioneine measurement	CACNA1A CPS1	7.22e-04	26	45	2	EFO_0021163
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 CPS1 CSGALNACT1	8.42e-04	121	45	3	EFO_0008595, EFO_0020943
Disease	level of Sphingomyelin (d38:1) in blood serum	SYNE2 SLC4A4	9.63e-04	30	45	2	OBA_2045180
Disease	neutrophil count	CACNA1A CD300LF SPTBN1 NAIP CPS1 SLC4A4 GKN1 PREX2	1.04e-03	1382	45	8	EFO_0004833
Disease	hepatocellular carcinoma (is_marker_for)	CTNNB1 CPS1 EZH2 PREX2	1.14e-03	301	45	4	DOID:684 (is_marker_for)
Disease	nephroblastoma (is_marker_for)	KDM4D CTNNB1	1.24e-03	34	45	2	DOID:2154 (is_marker_for)
Disease	Neoplastic Cell Transformation	CTNNB1 EZH2 PGBD5	1.26e-03	139	45	3	C0007621
Disease	triacylglycerol 58:8 measurement	DSP LTBP1	1.31e-03	35	45	2	EFO_0010442
Disease	lung squamous cell carcinoma (is_marker_for)	CTNNB1 PREX2	1.39e-03	36	45	2	DOID:3907 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAKMQKGYNSQMRSE	NAIP	46	Q13075
QPGAQRMYKQSMAQR	CACNA1A	41	O00555
TCGKADNNMQGNKMY	EOMES	336	O95936
TPEQYKMCMQSKAMN	CSGALNACT1	486	Q8TDX6
CALKRMYVNNMPDLN	BMP2K	76	Q9NSY1
MNKMPAGEQECEYNK	CBLL2	1	Q8N7E2
NDMKTMFRNCRKYNG	CECR2	501	Q9BXF3
VGKPLYQSMNCKPMQ	FBXO42	631	Q6P3S6
NYKNKMMVCQVGGIE	CTNNB1	431	P35222
PSNSPGNKKMMIYCN	HSFX4	151	A0A1B0GTS1
GNKKMMIYCNSNFQR	HSFX4	156	A0A1B0GTS1
CKPEQQMMYAGSKNR	GMFG	96	O60234
VNPNCYAKVMMVNGD	EZH2	691	Q15910
KCPKKPSYHGYNQMM	LTBP1	596	Q14766
METMKSKANCAQNPN	KDM4D	1	Q6B0I6
QNNFSPKGMMKLCSA	NLRP5	1131	P59047
PSNSPGNKKMMIYCN	HSFX3	151	A0A1B0GWH4
GNKKMMIYCNSNFQR	HSFX3	156	A0A1B0GWH4
GQYQIKMKGNMSLIC	PGBD5	391	Q8N414
TRQCVYMMKQPQGEQ	CUBN	731	O60494
SMCQNLGYNVTKMPN	FZD4	51	Q9ULV1
AKTYKMSMANRGQNQ	CPS1	306	P31327
KNIANMCRGIPTYMA	GKN1	136	Q9NS71
MKYQQKAAGMSPEQV	CD300LF	181	Q8TDQ1
REMRQMGQPCDAYQK	DSP	126	P15924
NSQMFQGRPCKNMYP	CPD	711	O75976
LKYQPMMQTIGQKYC	LYG1	66	Q8N1E2
MKPINKCIGRNMTYF	MFSD12	331	Q6NUT3
SYIMKQCVFMENPNK	C2CD5	941	Q86YS7
GYPALMDCMNKLKNN	NIPSNAP1	131	Q9BPW8
NKSDKMMNNNYDCPL	PKP1	516	Q13835
RKCQALKPMYSMMNG	FOXF1	146	Q12946
CKPEQQMMYAGSKNK	GMFB	96	P60983
GECQNINKQYMMVKS	SYNE2	551	Q8WXH0
GMQALYKVKSCSMAP	HEPH	356	Q9BQS7
MKNKMEIQGNPKYRA	MYBPH	416	Q13203
SKMRANNQKVYMPRE	SPTBN1	371	Q01082
MPYKCSSCSQQFMQK	ZBTB48	376	P10074
KSQLMCQQMYMGEKP	ZNF268	261	Q14587
QGEKLYKMMCRQGNL	PREX2	381	Q70Z35
PRNTYQCAMGKQAMG	POLR3B	681	Q9NW08
LSRAKKGMYCIGNMQ	ZNFX1	1221	Q9P2E3
QLNKMPNCMAVSQDY	WDR93	101	Q6P2C0
DKRKNMYSGGENVQM	SLC4A4	401	Q9Y6R1
QMDNMLVQTNKPYKC	ZBTB2	436	Q8N680
QSPRNMYQCQMGKQT	POLR1B	681	Q9H9Y6
MRASPGLSMYDQKKC	TRIM66	1036	O15016
NTEEMKMKNPGRYQI	TBC1D3I	116	A0A087WXS9
MYKMNICNKPSNKTA	ZDHHC1	1	Q8WTX9
GLCGNYDKNRKNDMM	ZAN	2466	Q9Y493
KCMYAPKPKVMQTCN	ADAMTSL3	461	P82987