Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 IRF8 ZNF226 ZNF626 GRHL2 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 NFYB ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.59e-07	1459	100	24	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF410 ZBTB38 ZNF146 IRF8 ZNF226 ZNF626 GRHL2 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 NFYB ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.70e-07	1244	100	22	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF410 ZBTB38 ZNF146 IRF8 ZNF226 ZNF626 GRHL2 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 NFYB ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	2.45e-07	1271	100	22	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZBTB38 ZNF146 ZNF674 PEG3 IRF8 ZNF226 ZNF626 GRHL2 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 NFYB ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	3.63e-07	1412	100	23	GO:0000981
GeneOntologyMolecularFunction	zinc ion binding	ZFAND2A TRAF3 TRAF5 USP45 ZNF146 ADAMTS3 TUT1 TRIM29 ZNF675 PHF2 AFG3L2 ERVK-5 ALB ZMYM1	1.39e-04	891	100	14	GO:0008270
GeneOntologyMolecularFunction	collagen binding involved in cell-matrix adhesion	ITGA1 ITGB1	2.46e-04	5	100	2	GO:0098639
GeneOntologyMolecularFunction	ErbB-3 class receptor binding	NRG1 NRG2	3.68e-04	6	100	2	GO:0043125
GeneOntologyMolecularFunction	uridylyltransferase activity	TUT1 UAP1L1	5.13e-04	7	100	2	GO:0070569
GeneOntologyMolecularFunction	5'-flap endonuclease activity	FAN1 GEN1	5.13e-04	7	100	2	GO:0017108
GeneOntologyMolecularFunction	flap endonuclease activity	FAN1 GEN1	6.82e-04	8	100	2	GO:0048256
GeneOntologyMolecularFunction	cell-matrix adhesion mediator activity	ITGA1 ITGB1	8.74e-04	9	100	2	GO:0098634
GeneOntologyMolecularFunction	thioesterase binding	TRAF3 TRAF5	1.09e-03	10	100	2	GO:0031996
GeneOntologyMolecularFunction	ATP-dependent diacylglycerol kinase activity	DGKA DGKE	1.33e-03	11	100	2	GO:0004143
GeneOntologyMolecularFunction	RNA polymerase III general transcription initiation factor activity	GTF3C6 GTF3C4	1.87e-03	13	100	2	GO:0000995
GeneOntologyCellularComponent	integrin alpha1-beta1 complex	ITGA1 ITGB1	2.18e-05	2	98	2	GO:0034665
GeneOntologyCellularComponent	transcription factor TFIIIC complex	GTF3C6 GTF3C4	3.22e-04	6	98	2	GO:0000127
GeneOntologyCellularComponent	integrin complex	ITGA1 ITGB1 ITGB4	4.49e-04	32	98	3	GO:0008305
MousePheno	centrally nucleated skeletal muscle fibers	NRG1 COL6A3 FLNC SYNE1 FBN2 AFG3L2	3.36e-06	80	72	6	MP:0009404
MousePheno	abnormal skeletal muscle fiber morphology	NRG1 COL6A3 FLNC SYNE1 ITGB1 FBN2 AFG3L2 FST	1.28e-05	212	72	8	MP:0003084
Domain	Znf_C2H2	ZNF410 ZBTB38 ZNF146 RBM10 ZNF674 PEG3 TUT1 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	5.68e-13	805	100	25	IPR007087
Domain	ZnF_C2H2	ZNF410 ZBTB38 ZNF146 RBM10 ZNF674 PEG3 TUT1 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	6.17e-13	808	100	25	SM00355
Domain	-	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	9.66e-13	679	100	23	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.51e-12	694	100	23	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF410 ZBTB38 ZNF146 RBM10 ZNF674 PEG3 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.92e-12	775	100	24	PS50157
Domain	Znf_C2H2-like	ZNF410 ZBTB38 ZNF146 RBM10 ZNF674 PEG3 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	3.39e-12	796	100	24	IPR015880
Domain	zf-C2H2	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 ZNF226 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.17e-11	693	100	22	PF00096
Domain	ZINC_FINGER_C2H2_1	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 ZNF226 ZNF831 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 MTF1 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	1.51e-11	777	100	23	PS00028
Domain	KRAB	ZNF674 ZNF226 ZNF626 ZNF568 ZNF675 ZNF34 ZNF182 ZNF716 ZNF257 ZNF197 ZNF737 ZNF808 ZNF543 ZNF738 ZNF726 ZNF426	7.43e-11	358	100	16	PS50805
Domain	KRAB	ZNF674 ZNF226 ZNF626 ZNF568 ZNF675 ZNF34 ZNF182 ZNF716 ZNF257 ZNF197 ZNF737 ZNF808 ZNF543 ZNF738 ZNF726 ZNF426	7.43e-11	358	100	16	PF01352
Domain	KRAB	ZNF674 ZNF226 ZNF626 ZNF568 ZNF675 ZNF34 ZNF182 ZNF716 ZNF257 ZNF197 ZNF737 ZNF808 ZNF543 ZNF738 ZNF726 ZNF426	1.16e-10	369	100	16	SM00349
Domain	KRAB	ZNF674 ZNF226 ZNF626 ZNF568 ZNF675 ZNF34 ZNF182 ZNF716 ZNF257 ZNF197 ZNF737 ZNF808 ZNF543 ZNF738 ZNF726 ZNF426	1.21e-10	370	100	16	IPR001909
Domain	zf-C2H2_6	PEG3 ZNF626 ZNF568 ZNF675 ZNF182 ZNF197 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	9.54e-07	314	100	11	PF13912
Domain	Neuregulin_C	NRG1 NRG2	8.48e-05	3	100	2	IPR002154
Domain	Neuregulin	NRG1 NRG2	8.48e-05	3	100	2	PF02158
Domain	ZF_CR	DNAJA2 DNAJA4	1.69e-04	4	100	2	PS51188
Domain	DnaJ	DNAJA2 DNAJA4	1.69e-04	4	100	2	IPR012724
Domain	DnaJ_CXXCXGXG	DNAJA2 DNAJA4	1.69e-04	4	100	2	PF00684
Domain	-	DNAJA2 DNAJA4	1.69e-04	4	100	2	2.10.230.10
Domain	HSP_DnaJ_Cys-rich_dom	DNAJA2 DNAJA4	2.81e-04	5	100	2	IPR001305
Domain	TNF_rcpt--assoc_TRAF	TRAF3 TRAF5	4.20e-04	6	100	2	IPR012227
Domain	Integrin_bsu_tail	ITGB1 ITGB4	5.86e-04	7	100	2	IPR012896
Domain	Integrin_B_tail	ITGB1 ITGB4	5.86e-04	7	100	2	SM01242
Domain	Integrin_B_tail	ITGB1 ITGB4	5.86e-04	7	100	2	PF07965
Domain	Integrin_beta	ITGB1 ITGB4	7.78e-04	8	100	2	PF00362
Domain	INB	ITGB1 ITGB4	7.78e-04	8	100	2	SM00187
Domain	Integrin_bsu_VWA	ITGB1 ITGB4	7.78e-04	8	100	2	IPR002369
Domain	zf-TRAF	TRAF3 TRAF5	7.78e-04	8	100	2	PF02176
Domain	VWFA	COL6A3 ITGA1 ITGB1 ITGB4	9.83e-04	82	100	4	PS50234
Domain	Integrin_bsu	ITGB1 ITGB4	9.97e-04	9	100	2	IPR015812
Domain	DnaJ_C	DNAJA2 DNAJA4	9.97e-04	9	100	2	IPR002939
Domain	DnaJ_C	DNAJA2 DNAJA4	9.97e-04	9	100	2	PF01556
Domain	Integin_beta_N	ITGB1 ITGB4	9.97e-04	9	100	2	IPR033760
Domain	TB	FBN2 FST	9.97e-04	9	100	2	PS51364
Domain	HSP40/DnaJ_pept-bd	DNAJA2 DNAJA4	9.97e-04	9	100	2	IPR008971
Domain	TB_dom	FBN2 FST	9.97e-04	9	100	2	IPR017878
Domain	INTEGRIN_BETA	ITGB1 ITGB4	9.97e-04	9	100	2	PS00243
Domain	PSI_integrin	ITGB1 ITGB4	9.97e-04	9	100	2	PF17205
Domain	VWA	COL6A3 ITGA1 ITGB1 ITGB4	1.08e-03	84	100	4	SM00327
Domain	DAGK_acc	DGKA DGKE	1.24e-03	10	100	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKA DGKE	1.24e-03	10	100	2	IPR000756
Domain	DAGKa	DGKA DGKE	1.24e-03	10	100	2	SM00045
Domain	MATH/TRAF_dom	TRAF3 TRAF5	1.81e-03	12	100	2	IPR002083
Domain	MATH	TRAF3 TRAF5	1.81e-03	12	100	2	PS50144
Domain	MATH	TRAF3 TRAF5	1.81e-03	12	100	2	SM00061
Domain	Znf_TRAF	TRAF3 TRAF5	1.81e-03	12	100	2	IPR001293
Domain	MATH	TRAF3 TRAF5	1.81e-03	12	100	2	PF00917
Domain	VWF_A	COL6A3 ITGA1 ITGB1 ITGB4	1.97e-03	99	100	4	IPR002035
Domain	ZF_TRAF	TRAF3 TRAF5	2.13e-03	13	100	2	PS50145
Domain	-	TRAF3 TRAF5	2.48e-03	14	100	2	3.90.890.10
Domain	-	TRAF3 TRAF5	2.48e-03	14	100	2	2.60.210.10
Domain	DAGKc	DGKA DGKE	2.48e-03	14	100	2	SM00046
Domain	EGF_1	NRG1 DLL4 NRG2 ITGB1 ITGB4 FBN2	2.50e-03	255	100	6	PS00022
Domain	EGF-like_CS	NRG1 DLL4 NRG2 ITGB1 ITGB4 FBN2	2.80e-03	261	100	6	IPR013032
Domain	Diacylglycerol_kinase_cat_dom	DGKA DGKE	2.85e-03	15	100	2	IPR001206
Domain	DAGK_cat	DGKA DGKE	2.85e-03	15	100	2	PF00781
Domain	DAGK	DGKA DGKE	2.85e-03	15	100	2	PS50146
Domain	SIAH-type	TRAF3 TRAF5	3.24e-03	16	100	2	IPR013323
Domain	Channel_four-helix_dom	KCNA4 KCNB1 SCN2A	3.53e-03	57	100	3	IPR027359
Domain	-	KCNA4 KCNB1 SCN2A	3.53e-03	57	100	3	1.20.120.350
Domain	NAD/diacylglycerol_kinase	DGKA DGKE	3.66e-03	17	100	2	IPR016064
Domain	Retrov_capsid_C	PEG3 ZNF197 ERVK-5	3.90e-03	59	100	3	IPR008916
Domain	EGF_extracell	DLL4 ITGB1 ITGB4	4.09e-03	60	100	3	IPR013111
Domain	EGF_2	DLL4 ITGB1 ITGB4	4.09e-03	60	100	3	PF07974
Domain	KAZAL_1	FST RECK	4.11e-03	18	100	2	PS00282
Domain	PLAC	ADAMTS3 PCSK6	4.57e-03	19	100	2	PS50900
Domain	PLAC	ADAMTS3 PCSK6	4.57e-03	19	100	2	IPR010909
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	2.47e-04	23	76	3	M47537
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	2.47e-04	23	76	3	M47720
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ERBB4_TO_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	NRG1 NRG2	2.84e-04	5	76	2	M48991
Pathway	REACTOME_GRB7_EVENTS_IN_ERBB2_SIGNALING	NRG1 NRG2	2.84e-04	5	76	2	M26937
Pathway	KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_PI3K_SIGNALING_PATHWAY	TRAF3 TRAF5	2.84e-04	5	76	2	M49020
Pathway	PID_INTEGRIN_CS_PATHWAY	ITGA1 ITGB1 ITGB4	3.58e-04	26	76	3	M47
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	3.58e-04	26	76	3	M47719
Pathway	PID_MYC_REPRESS_PATHWAY	IRF8 ITGB1 ITGB4 NFYB	3.65e-04	63	76	4	M254
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	4.48e-04	28	76	3	M47655
Pathway	REACTOME_LAMININ_INTERACTIONS	ITGA1 ITGB1 ITGB4	5.51e-04	30	76	3	M27216
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	5.51e-04	30	76	3	M47724
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY	ITGA1 ITGB1 ITGB4	5.51e-04	30	76	3	M47718
Pathway	BIOCARTA_AGR_PATHWAY	NRG1 NRG2 ITGB1	7.31e-04	33	76	3	M6220
Pathway	WP_13Q1212_COPY_NUMBER_VARIATION	FLNC TRAF3 TRAF5	7.99e-04	34	76	3	M48103
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF626 ZNF34 ZNF182 ZNF257 ZNF197 ZNF737 ZNF543 ZNF738 ZNF726	2.90e-09	181	100	9	37372979
Pubmed	Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI.	COL6A3 ITGA1 ITGB1	4.58e-07	6	100	3	8387021
Pubmed	Characterization of integrin engagement during defined human embryonic stem cell culture.	ITGA1 ITGB1 ITGB4	1.91e-06	9	100	3	19933311
Pubmed	Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.	ITGA1 ITGB1 ITGB4	1.91e-06	9	100	3	1693624
Pubmed	Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells.	ITGA1 ITGB1 ITGB4	1.91e-06	9	100	3	25808196
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF410 RBM10 PEG3 IRF8 ZNF626 GRHL2 PHF2 ZNF716 MTF1 NFYB ZNF726 ZNF426	3.69e-06	808	100	12	20412781
Pubmed	Immunolocalization of extracellular matrix components and integrins during mouse liver development.	ITGA1 ITGB1 ITGB4	3.74e-06	11	100	3	15368439
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GATD3 ZBTB38 SYNE1 DNAJA2 PEG3 GTF3C4 FAN1 WDR47 ZNF34 SF3B1 PCSK6 ZNF197 GEN1 UAP1L1 RECK	4.02e-06	1285	100	15	35914814
Pubmed	Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells.	ITGB1 ITGB4 BMPR1B	4.98e-06	12	100	3	15913604
Pubmed	Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system.	NRG1 ITGB1 ITGB4	4.98e-06	12	100	3	24687281
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	FLNC RANBP2 ERCC6L ICE2 ITGB1 GTF3C4 SF3B1 BRCA2 ZMYM1	5.67e-06	444	100	9	34795231
Pubmed	K+ channel alterations in the progression of experimental autoimmune encephalomyelitis.	KCNA4 KCNB1	8.18e-06	2	100	2	22560931
Pubmed	Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population.	NRG1 ITGB4	8.18e-06	2	100	2	32418639
Pubmed	Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease.	TRAF3 TRAF5	8.18e-06	2	100	2	23329887
Pubmed	Plumieribetin, a fish lectin homologous to mannose-binding B-type lectins, inhibits the collagen-binding alpha1beta1 integrin.	ITGA1 ITGB1	8.18e-06	2	100	2	19850917
Pubmed	Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5.	TRAF3 TRAF5	8.18e-06	2	100	2	23150880
Pubmed	Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis.	ITGA1 ITGB1	8.18e-06	2	100	2	9885280
Pubmed	Expression of native and truncated forms of the human integrin alpha 1 subunit.	ITGA1 ITGB1	8.18e-06	2	100	2	8428973
Pubmed	α1β1 integrin-mediated adhesion inhibits macrophage exit from a peripheral inflammatory lesion.	ITGA1 ITGB1	8.18e-06	2	100	2	23509351
Pubmed	Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.	ITGA1 ITGB1	8.18e-06	2	100	2	17660399
Pubmed	A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy.	ITGB1 ITGB4	8.18e-06	2	100	2	29700202
Pubmed	The group B streptococcal alpha C protein binds alpha1beta1-integrin through a novel KTD motif that promotes internalization of GBS within human epithelial cells.	ITGA1 ITGB1	8.18e-06	2	100	2	18048918
Pubmed	NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis.	NRG1 NRG2	8.18e-06	2	100	2	34996744
Pubmed	Integrin alpha1beta1 is involved in the differentiation into myofibroblasts in adult reactive tissues in vivo.	ITGA1 ITGB1	8.18e-06	2	100	2	19397781
Pubmed	Deletion of diacylglycerol kinase ε confers susceptibility to obesity via reduced lipolytic activity in murine adipocytes.	DGKA DGKE	8.18e-06	2	100	2	29509511
Pubmed	Very late antigen-1 mediates corneal lymphangiogenesis.	ITGA1 ITGB1	8.18e-06	2	100	2	21372020
Pubmed	Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis.	ITGA1 ITGB1	8.18e-06	2	100	2	12488427
Pubmed	Integrin α1β1 participates in chondrocyte transduction of osmotic stress.	ITGA1 ITGB1	8.18e-06	2	100	2	24495803
Pubmed	Analysis of albumin-associated peptides and proteins from ovarian cancer patients.	BRCA2 ALB	8.18e-06	2	100	2	16099937
Pubmed	Immunohistochemical localization of beta1 and beta4 integrins in mouse endometrium during implantation and early pregnancy.	ITGB1 ITGB4	8.18e-06	2	100	2	16268053
Pubmed	Integrators of epidermal growth and differentiation: distinct functions for beta 1 and beta 4 integrins.	ITGB1 ITGB4	8.18e-06	2	100	2	9388785
Pubmed	Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association.	RBM10 TUT1	8.18e-06	2	100	2	34576144
Pubmed	Alpha1 and beta1 integrins enhance the homing and differentiation of cultured prostate cancer stem cells.	ITGA1 ITGB1	8.18e-06	2	100	2	20531279
Pubmed	Bioactive recombinant neuregulin-1, -2, and -3 expressed in Escherichia coli.	NRG1 NRG2	8.18e-06	2	100	2	15039062
Pubmed	Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.	ITGA1 ITGB1	8.18e-06	2	100	2	16775606
Pubmed	Crystal structure of the alpha1beta1 integrin I domain in complex with an antibody Fab fragment.	ITGA1 ITGB1	8.18e-06	2	100	2	12662928
Pubmed	Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.	KCNA4 KCNB1	8.18e-06	2	100	2	20643768
Pubmed	Key role of alpha(1)beta(1)-integrin in the activation of PI3-kinase-Akt by flow (shear stress) in resistance arteries.	ITGA1 ITGB1	8.18e-06	2	100	2	18245559
Pubmed	Dendrofalconerol A suppresses migrating cancer cells via EMT and integrin proteins.	ITGA1 ITGB4	8.18e-06	2	100	2	25550552
Pubmed	Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1.	ITGA1 ITGB1	8.18e-06	2	100	2	15485856
Pubmed	Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase.	DGKA DGKE	8.18e-06	2	100	2	18702510
Pubmed	Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.	ITGA1 ITGB1 ITGB4	1.02e-05	15	100	3	15366018
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	COL6A3 ITGA1 ITGB1 FBN2	1.34e-05	50	100	4	23658023
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	COL6A3 FLNC RANBP2 ZBTB38 SYNE1 PEG3 ITGB1 AFG3L2 ZNF426	1.39e-05	497	100	9	23414517
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP45 PEG3 DGKA DEPDC1 ITGB1 ITGB4 ZNF568 SIAE ZNF182 ZMYM1 GEN1 ZNF726 LMBRD1	1.41e-05	1084	100	13	11544199
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RANBP2 RBM10 GTF3C4 PHF2 SF3B1 ALB WDR48	1.43e-05	272	100	7	31010829
Pubmed	TSC2 modulates cell adhesion and migration via integrin-α1β1.	ITGA1 ITGB1	2.45e-05	3	100	2	22923640
Pubmed	TRAF2 regulates peripheral CD8(+) T-cell and NKT-cell homeostasis by modulating sensitivity to IL-15.	IL15 TRAF3	2.45e-05	3	100	2	25931426
Pubmed	Responses of endothelial cell and astrocyte matrix-integrin receptors to ischemia mimic those observed in the neurovascular unit.	ITGA1 ITGB1	2.45e-05	3	100	2	18032737
Pubmed	Crystal structure of α5β1 integrin ectodomain: atomic details of the fibronectin receptor.	ITGA1 ITGB1	2.45e-05	3	100	2	22451694
Pubmed	Variants of the alpha 6 beta 1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin alpha 6 subunit.	ITGB1 ITGB4	2.45e-05	3	100	2	8081870
Pubmed	Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.	ITGA1 ITGB1	2.45e-05	3	100	2	17237400
Pubmed	IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells.	IL15 ITGA1	2.45e-05	3	100	2	28952190
Pubmed	Expression of estrogen receptor beta increases integrin alpha1 and integrin beta1 levels and enhances adhesion of breast cancer cells.	ITGA1 ITGB1	2.45e-05	3	100	2	19780039
Pubmed	Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.	ITGA1 ITGB1	2.45e-05	3	100	2	24939421
Pubmed	The crucial role of collagen-binding integrins in maintaining the mechanical properties of human scleral fibroblasts-seeded collagen matrix.	ITGA1 ITGB1	2.45e-05	3	100	2	21647271
Pubmed	Salivary gland tumours: immunoexpression of integrins beta 1, beta 3 and beta 4.	ITGB1 ITGB4	2.45e-05	3	100	2	12694355
Pubmed	Integrin alpha1beta1 mediates collagen induction of MMP-13 expression in MC615 chondrocytes.	ITGA1 ITGB1	2.45e-05	3	100	2	16198011
Pubmed	Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin.	ITGA1 ITGB1	2.45e-05	3	100	2	18587047
Pubmed	The ß1-integrin-dependent function of RECK in physiologic and tumor angiogenesis.	ITGB1 RECK	2.45e-05	3	100	2	20407016
Pubmed	An interstitial telomere array proximal to the distal telomere of mouse chromosome 13.	ETFA ITGA1	2.45e-05	3	100	2	9166585
Pubmed	Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells.	ITGA1 ITGB1	2.45e-05	3	100	2	12960301
Pubmed	Determination of the ligand-binding specificities of the alpha2beta1 and alpha1beta1 integrins in a novel 3-dimensional in vitro model of pancreatic cancer.	ITGA1 ITGB1	2.45e-05	3	100	2	17312461
Pubmed	RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in Mice.	ITGB1 RECK	2.45e-05	3	100	2	26247610
Pubmed	Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer.	ITGA1 ITGB1	2.45e-05	3	100	2	18676835
Pubmed	Semaphorin7A aggravates coxsackievirusB3-induced viral myocarditis by increasing α1β1-integrin macrophages and subsequent enhanced inflammatory response.	ITGA1 ITGB1	2.45e-05	3	100	2	29108785
Pubmed	Timing of gene expression and oolemma localization of mouse alpha6 and beta1 integrin subunits during oogenesis.	ITGA1 ITGB1	2.45e-05	3	100	2	9698453
Pubmed	Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines.	ITGB1 ITGB4	2.45e-05	3	100	2	2649503
Pubmed	The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties.	ITGB1 ITGB4	2.45e-05	3	100	2	1698797
Pubmed	Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction.	ITGA1 ITGB1	2.45e-05	3	100	2	18832573
Pubmed	Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.	ITGA1 ITGB1	2.45e-05	3	100	2	17339338
Pubmed	Genetic deletion or antibody blockade of alpha1beta1 integrin induces a stable plaque phenotype in ApoE-/- mice.	ITGA1 ITGB1	2.45e-05	3	100	2	15976328
Pubmed	Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.	TRAF3 TRAF5	2.45e-05	3	100	2	26454171
Pubmed	Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.	ITGA1 ITGB1	2.45e-05	3	100	2	17377534
Pubmed	Plakophilin 2 affects cell migration by modulating focal adhesion dynamics and integrin protein expression.	ITGB1 ITGB4	2.45e-05	3	100	2	23884246
Pubmed	TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4.	ITGB1 ITGB4	2.45e-05	3	100	2	37221403
Pubmed	Integrin α1/β1 and α2/β1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy.	ITGA1 ITGB1	2.45e-05	3	100	2	22298882
Pubmed	Integrin alpha 6B beta 1 is involved in kidney tubulogenesis in vitro.	ITGB1 ITGB4	2.45e-05	3	100	2	9013328
Pubmed	The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone.	NRG1 NRG2	2.45e-05	3	100	2	16446434
Pubmed	Impact of integrin-matrix interaction and signaling on insulin gene expression and the mesenchymal transition of human beta-cells.	ITGA1 ITGB1	2.45e-05	3	100	2	20232313
Pubmed	The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol.	DGKA DGKE	2.45e-05	3	100	2	15544348
Pubmed	Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.	NRG1 ADAMTS3 DLL4	4.47e-05	24	100	3	29791855
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNC RANBP2 DOCK11 ICE2 DNAJA2 LRRC59 ZFP91 ZMYM1 GEN1 WDR48	4.62e-05	724	100	10	36232890
Pubmed	Cross-talk of SFRP4, integrin α1β1, and Notch1 inhibits cardiac differentiation of P19CL6 cells.	ITGA1 ITGB1	4.89e-05	4	100	2	27542621
Pubmed	A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1.	ITGA1 ITGB1	4.89e-05	4	100	2	16043429
Pubmed	Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.	NRG1 NRG2	4.89e-05	4	100	2	17598910
Pubmed	Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation.	ITGA1 ITGB1	4.89e-05	4	100	2	23284937
Pubmed	TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.	TRAF3 TRAF5	4.89e-05	4	100	2	15708970
Pubmed	Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.	ITGB1 ITGB4	4.89e-05	4	100	2	9660880
Pubmed	Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis.	ITGA1 ITGB1	4.89e-05	4	100	2	20864678
Pubmed	Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes.	ITGB1 ITGB4	4.89e-05	4	100	2	16707493
Pubmed	The alpha 1 beta 1 and alpha E beta 7 integrins define a subset of dendritic cells in peripheral lymph nodes with unique adhesive and antigen uptake properties.	ITGA1 ITGB1	4.89e-05	4	100	2	14688336
Pubmed	Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.	ITGB1 ITGB4	4.89e-05	4	100	2	24505282
Pubmed	CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.	TRAF3 TRAF5	4.89e-05	4	100	2	9582383
Pubmed	Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.	ITGA1 ITGB1	4.89e-05	4	100	2	27929375
Pubmed	Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development.	ITGB1 ITGB4	4.89e-05	4	100	2	8834471
Pubmed	Alpha 6 integrins participate in pro-T cell homing to the thymus.	ITGB1 ITGB4	4.89e-05	4	100	2	7621877
Pubmed	Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains.	ITGA1 ITGB1	4.89e-05	4	100	2	16754661
Pubmed	Human fallopian tube epithelium constitutively expresses integrin endometrial receptivity markers: no evidence for a tubal implantation window.	ITGA1 ITGB1	4.89e-05	4	100	2	22002573
Pubmed	The laminin alpha2-chain short arm mediates cell adhesion through both the alpha1beta1 and alpha2beta1 integrins.	ITGA1 ITGB1	4.89e-05	4	100	2	9361014
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF626 ZNF675 ZNF257 ZNF737 ZNF738 ZNF726	3.02e-07	122	100	6	chr19p12
Cytoband	19p12	ZNF626 ZNF675 ZNF737 ZNF738 ZNF726	1.68e-06	90	100	5	19p12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF410 ZBTB38 ZNF146 ZNF674 PEG3 ZNF226 ZNF626 ZNF568 ZFX ZNF675 ZNF34 ZNF182 ZNF716 ZNF257 ZNF197 ZFP91 ZNF737 ZNF808 ZNF543 ZNF726 ZNF426	4.69e-14	718	66	21	28
GeneFamily	TNF receptor associated factors	TRAF3 TRAF5	2.72e-04	7	66	2	1056
GeneFamily	CD molecules\|Integrin beta subunits	ITGB1 ITGB4	4.65e-04	9	66	2	1159
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKA DGKE	5.80e-04	10	66	2	1178
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TRAF3 LYAR	1.34e-03	15	66	2	26
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	RANBP2 RBM10	2.64e-03	21	66	2	89
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	GTF3C6 GTF3C4	3.73e-03	25	66	2	565
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	ERCC6L NSD2 DEPDC1 ZNF831 RTKN2 SASS6 ZMYM1	9.15e-06	194	99	7	M7467
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNC CCDC73 DEPDC1 ZNF831 BRCA2 SASS6 GEN1	3.36e-09	103	99	7	eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 ZNF257 GEN1 ZNF726	2.06e-07	187	99	7	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	ASK440-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	TRAF5 THEMIS DGKA ITGA1 ZNF831 TRIM29 RTKN2	2.22e-07	189	99	7	868a387d19eb02bf41933e786b7d23e920a5d433
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8\|bone_marrow / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831 ITGB1	2.30e-07	190	99	7	be281c7c717c11ef3c5cbccd22628acf1bd9727f
ToppCell	COVID-CD8\|COVID / Condition, Cell_class and T cell subcluster	TRAF5 THEMIS SYNE1 PARP8 ITGA1 LYAR ZNF831	2.94e-07	197	99	7	4c61ea7eba706bdc7345745941ae8b9f6a21e844
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERCC6L DEPDC1 CD5L BRCA2 SASS6 GEN1	1.75e-06	163	99	6	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC1 RTKN2 BRCA2 ZNF257 GEN1 ZNF726	3.31e-06	182	99	6	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	3.31e-06	182	99	6	f857b32de19240a8aca1685f7a78b4e53b04875c
ToppCell	Healthy/Control-CD4+_CTL\|Healthy/Control / Disease group and Cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	3.52e-06	184	99	6	6c6ffa150f81e456f88e9065de90c2dcda417589
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8\|blood / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	3.99e-06	188	99	6	21730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERCC6L NSD2 DEPDC1 BRCA2 SASS6 GEN1	4.11e-06	189	99	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Tem/emra_CD8\|blood / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	4.24e-06	190	99	6	5624f711b34132081f93fa70702316962e3e3c64
ToppCell	facs-Thymus-Epithelium-24m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 TRIM29 GRHL2 KCNB1 PCSK6 FST	4.37e-06	191	99	6	eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 TRIM29 GRHL2 KCNB1 PCSK6 FST	4.37e-06	191	99	6	1730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS PARP8 ITGA1 LYAR ZNF831 ITGB1	4.37e-06	191	99	6	142f98cabf8737b28369315b3d7a0797ded88e03
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8\|bone_marrow / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	4.37e-06	191	99	6	db7b8f8826bf19d6eeee14319570a9e6e99ab2cb
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 TRIM29 GRHL2 KCNB1 PCSK6 FST	4.37e-06	191	99	6	4b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	4.37e-06	191	99	6	4a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	4.50e-06	192	99	6	7a122505d7adf236e0cbd9bcbc98e7c537600ca3
ToppCell	IIH-CD8\|IIH / Condition, Cell_class and T cell subcluster	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	4.64e-06	193	99	6	343ac8c6dc6d7c7a944a14de65f1d4ea3dfafe86
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NSD2 DEPDC1 RTKN2 BRCA2 SASS6 GEN1	4.64e-06	193	99	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 THEMIS SYNE1 PARP8 ITGA1 LYAR	4.64e-06	193	99	6	778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERCC6L NSD2 DEPDC1 BRCA2 PCSK6 SASS6	4.64e-06	193	99	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	4.64e-06	193	99	6	523e2541f9f8d22b3c5263839a57cc1ab23d4963
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 THEMIS SYNE1 PARP8 ITGA1 LYAR	4.78e-06	194	99	6	b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	4.92e-06	195	99	6	42382653e977714bff453bece26a6cd66ea2cc1f
ToppCell	T_cells-GZMK+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	IL15 ZBTB38 SYNE1 PARP8 ITGA1 LYAR	4.92e-06	195	99	6	003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	5.07e-06	196	99	6	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	5.07e-06	196	99	6	093fb240e72911dfd360aa6edf8ed2d611c78a1e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	5.07e-06	196	99	6	c06caba0c91b8ee66f42bc43ec75eb2475f07056
ToppCell	COVID-19_Severe-CD8+_Tem\|COVID-19_Severe / disease group, cell group and cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ZNF831	5.07e-06	196	99	6	1bc1ec3351319c5d2daa0808cf161a7327e1758e
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	ERCC6L NSD2 DEPDC1 BRCA2 ZNF808 GEN1	5.22e-06	197	99	6	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THEMIS SYNE1 PARP8 LYAR ZNF831 ITGB1	5.53e-06	199	99	6	db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERCC6L NSD2 DEPDC1 BRCA2 SASS6 GEN1	5.53e-06	199	99	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	ERCC6L NSD2 DEPDC1 BRCA2 SASS6 GEN1	5.69e-06	200	99	6	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_Tem\|Control / Disease, condition lineage and cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	5.69e-06	200	99	6	fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCell	severe-CD8+_Tem\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	5.69e-06	200	99	6	aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF5 THEMIS DOCK11 PARP8 DGKA ZNF831	5.69e-06	200	99	6	e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCell	severe-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	5.69e-06	200	99	6	6aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCell	mild-CD8+_Tem\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 THEMIS SYNE1 PARP8 LYAR ITGB1	5.69e-06	200	99	6	a7870c5728b2c17d1d0e4fe728599f186966861b
ToppCell	3'_v3-Lung-Lymphocytic_T_CD8-Trm_gut_CD8\|Lung / Manually curated celltypes from each tissue	TRAF5 THEMIS PARP8 ITGA1 TXNDC16	1.59e-05	141	99	5	7cbe8abdd004430d58ce31e0b613894a4cf6726e
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17\|blood / Manually curated celltypes from each tissue	C9orf85 ZNF674 NRG2 ZNF726 RECK	2.67e-05	157	99	5	c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ZNF410 ZNF675 ZNF197 RECK WDR48	2.83e-05	159	99	5	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ZNF410 ZNF675 ZNF197 RECK WDR48	2.83e-05	159	99	5	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRIM29 ITGB4 BMPR1B ZNF543 FST	3.10e-05	162	99	5	112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ZBTB38 PEG3 SLC7A14 FBN2	3.28e-05	164	99	5	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAND2A DOCK11 IRF8 BRCA2 ZNF808	3.58e-05	167	99	5	881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 THEMIS SYNE1 LYAR ITGB1	3.68e-05	168	99	5	b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 ZFP91	3.79e-05	169	99	5	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 SCN2A	3.79e-05	169	99	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	COVID-19_Severe-CD4+_CTL\|World / disease group, cell group and cell class	THEMIS SYNE1 PARP8 ITGB1 ANGPTL7	3.79e-05	169	99	5	8c8168ac93a808d7b4756e4491db2b2979df1c1f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 ZFP91	4.24e-05	173	99	5	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK11 PARP8 LYAR ZNF257 ZNF426	4.24e-05	173	99	5	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERCC6L NSD2 DEPDC1 RTKN2 BRCA2	4.35e-05	174	99	5	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TRIM29 ITGB4 BMPR1B TXNRD3 ZNF426	4.35e-05	174	99	5	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT\|blood / Manually curated celltypes from each tissue	USP45 THEMIS PARP8 LYAR KCNB1	4.47e-05	175	99	5	b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 GEN1	4.47e-05	175	99	5	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS3 DEPDC1 ITGA1 FST RECK	4.72e-05	177	99	5	2b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCell	COVID-19_Severe-CD4+_CTL\|COVID-19_Severe / disease group, cell group and cell class	THEMIS SYNE1 PARP8 LYAR ANGPTL7	4.72e-05	177	99	5	34e9455790bae905dd91923792f4109d18b7686e
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERCC6L NSD2 PEG3 DEPDC1 SASS6	4.72e-05	177	99	5	8a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP2 ZBTB38 SYNE1 IRF8 ITGA1	4.85e-05	178	99	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	NRG1 TRIM29 GRHL2 ITGB4 BMPR1B	4.98e-05	179	99	5	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS3 ITGA1 ITGB1 FST RECK	4.98e-05	179	99	5	56db12467b445f2b8ef92af50779eeab10413eb2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 SCN2A	5.12e-05	180	99	5	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NRG1 TRIM29 GRHL2 ITGB4 BMPR1B	5.25e-05	181	99	5	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 ADAMTS3 DOCK11 GRHL2 FBN2	5.39e-05	182	99	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG2 TRIM29 GRHL2 ITGB4 FBN2	5.53e-05	183	99	5	ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCell	facs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG2 TRIM29 GRHL2 ITGB4 FBN2	5.53e-05	183	99	5	f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	NSD2 IRF8 DEPDC1 BRCA2 GEN1	5.82e-05	185	99	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 SYNE1 PARP8 LYAR ANGPTL7	5.82e-05	185	99	5	097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 GEN1	5.82e-05	185	99	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 ADAMTS3 DOCK11 GRHL2 FBN2	5.98e-05	186	99	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	Healthy/Control-CD4+_CTL\|World / Disease group and Cell class	THEMIS SYNE1 PARP8 LYAR ITGB1	6.13e-05	187	99	5	d54d3214d77a9469e94a16c00a80626fd4953e2b
ToppCell	mild_COVID-19-CD4+_CTL\|mild_COVID-19 / disease group, cell group and cell class (v2)	ZBTB38 THEMIS SYNE1 LYAR ITGB1	6.13e-05	187	99	5	49196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCell	Control-Lymphocyte-T_NK-CD8_TEM\|Control / Disease, Lineage and Cell Type	ZBTB38 THEMIS SYNE1 LYAR ITGB1	6.13e-05	187	99	5	7fdff970a9397305d0b8194c00a043cc69dcca12
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS SYNE1 NRG2 LYAR ITGB1	6.13e-05	187	99	5	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 DEPDC1 RTKN2 BRCA2 GEN1	6.13e-05	187	99	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	NRG1 TRIM29 GRHL2 ITGB4 BMPR1B	6.13e-05	187	99	5	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS SYNE1 PARP8 LYAR ZNF831	6.29e-05	188	99	5	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL15 ADAMTS3 DOCK11 SYNE1 FBN2	6.29e-05	188	99	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF5 IRF8 DGKA TXNDC16 LMBRD1	6.29e-05	188	99	5	1f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF5 IRF8 DGKA TXNDC16 LMBRD1	6.29e-05	188	99	5	85746f95319e494efdc1bbc24331698688d3a900
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL15 ADAMTS3 DOCK11 SYNE1 FBN2	6.29e-05	188	99	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS SYNE1 PARP8 LYAR ZNF831	6.29e-05	188	99	5	8155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCell	COVID-19-kidney-T-cells-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THEMIS PARP8 DGKE ZNF831 DNAJA4	6.29e-05	188	99	5	15484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCell	NS-critical-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TRAF5 THEMIS PARP8 ITGA1 ZNF831	6.44e-05	189	99	5	fb7572fb4c7c43886d57a025decad076f32a14c4
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8-Trm/em_CD8\|bone_marrow / Manually curated celltypes from each tissue	ZBTB38 THEMIS PARP8 LYAR ZNF831	6.44e-05	189	99	5	17733be6ead1d24149d478023f731d23876b4f54
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS3 ITGA1 ITGB1 FST RECK	6.44e-05	189	99	5	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	3'_v3-blood-Lymphocytic_T_CD8\|blood / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR	6.61e-05	190	99	5	5dca8654964c41580fa3b094579fe7cb296d406f
ToppCell	control-CD8+_Tem\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 THEMIS SYNE1 LYAR ITGB1	6.61e-05	190	99	5	1200074e358f164d36bf22800a17ce0fca319560
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERCC6L DEPDC1 BRCA2 PCSK6 GEN1	6.61e-05	190	99	5	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	facs-Skin-Anagen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKA TRIM29 PCSK6 TXNRD3 ALB	6.61e-05	190	99	5	888ded899f0513d41bf655896d59ae8ef74e0978
ToppCell	10x5'-blood-Lymphocytic_T_CD8-Trm/em_CD8\|blood / Manually curated celltypes from each tissue	ZBTB38 THEMIS SYNE1 PARP8 LYAR	6.61e-05	190	99	5	e1f474dc36bf9eaf457b14a8761d287904754cdc
ToppCell	facs-Skin-Anagen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKA TRIM29 PCSK6 TXNRD3 ALB	6.61e-05	190	99	5	3466cebab16964e94da130d0673fa32e7d90b5ed
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ZBTB38 SYNE1 PARP8 LYAR ITGB1	6.61e-05	190	99	5	66d29f53f129fc18771f6214316a913eeaccd55e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS3 ITGA1 ITGB1 FST RECK	6.61e-05	190	99	5	10b02c62e72bfea9767e3e751011436925da823e
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 THEMIS SYNE1 LYAR ITGB1	6.77e-05	191	99	5	b2d0ea24970da09209da9d9dda76e30fbfe22917
ToppCell	COVID-19-kidney-T-cells-2\|kidney / Disease (COVID-19 only), tissue and cell type	THEMIS PARP8 DGKE ZNF831 DNAJA4	6.77e-05	191	99	5	698e6a28276704f8baa082d028db2345b973c4bc
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 THEMIS SYNE1 PARP8 LYAR	6.77e-05	191	99	5	752e31a4b8aab9243b0451f4c40c2940ae9a5252
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS SYNE1 PARP8 LYAR ZNF831	6.77e-05	191	99	5	b9ef6d82b86271b7e0875a399bb9aae84ef5bad3
Disease	Astrocytosis	ITGA1 ITGB1 ITGB4	2.20e-05	17	96	3	C3887640
Disease	Gliosis	ITGA1 ITGB1 ITGB4	2.20e-05	17	96	3	C0017639
Disease	gamma wave measurement	NRG2 ZFX	1.04e-04	5	96	2	EFO_0008388
Disease	Membranoproliferative Glomerulonephritis, Type I	DGKE ALB	1.56e-04	6	96	2	C0268742
Disease	Membranoproliferative Glomerulonephritis, Type III	DGKE ALB	1.56e-04	6	96	2	C1720821
Disease	Aplasia Cutis Congenita	DLL4 ITGB4	1.56e-04	6	96	2	C0282160
Disease	immunoglobulin isotype switching measurement	TRAF3 PARP8 IRF8	4.01e-04	44	96	3	EFO_0010128
Disease	Hemolytic-Uremic Syndrome	DGKE ALB	5.65e-04	11	96	2	C0019061
Disease	middle cerebral artery infarction (is_implicated_in)	NRG1 ALB	6.77e-04	12	96	2	DOID:3525 (is_implicated_in)
Disease	brain disease (is_implicated_in)	RANBP2 TRAF3	6.77e-04	12	96	2	DOID:936 (is_implicated_in)
Disease	acute myeloid leukemia (implicated_via_orthology)	SF3B1 ZFP91	6.77e-04	12	96	2	DOID:9119 (implicated_via_orthology)
Disease	fructose measurement	NRG1 BMPR1B	7.98e-04	13	96	2	EFO_0010477
Disease	Diverticular Bleeding	ETFA BMPR1B	7.98e-04	13	96	2	C4505353
Disease	transmembrane protein 87B measurement	NRG1 PCSK6	7.98e-04	13	96	2	EFO_0802158
Disease	Diverticular Diseases	ETFA BMPR1B	7.98e-04	13	96	2	C4317009
Disease	muscular dystrophy (is_implicated_in)	COL6A3 SYNE1	1.38e-03	17	96	2	DOID:9884 (is_implicated_in)
Disease	Non-Small Cell Lung Carcinoma	LRRC59 ITGB1 ITGB4 RECK	1.71e-03	156	96	4	C0007131
Disease	amblyopia	PARP8 ZNF675	2.32e-03	22	96	2	MONDO_0001020
Disease	Malignant neoplasm of breast	NRG1 DLL4 NSD2 SYNE1 IRF8 DGKE TRIM29 BRCA2 FST GEN1	2.61e-03	1074	96	10	C0006142
Disease	Nephritis, Interstitial	FAN1 ALB	2.76e-03	24	96	2	C0027707
Disease	Liver Failure, Acute	ALB FST	2.76e-03	24	96	2	C0162557

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAFVEKCCKADDKET	ALB	576	P02768
KFKDVAGCEEAKLEI	AFG3L2	306	Q9Y4W6
KKELEVDCGLDKSNC	DLL4	591	Q9NR61
KEDQVVCKQLGCGKS	CD5L	276	O43866
KLALQKNVICEKCEG	DNAJA4	126	Q8WW22
KNILVKKNGTCCIAD	BMPR1B	336	O00238
TKEVADCFKKTFEEC	RANBP2	3026	P49792
EKCFKCGVPKSEAEQ	RBM10	231	P98175
ICKSDCVEILKKCGD	RECK	431	O95980
CVQCRAFNKGEKKDT	ITGB1	646	P05556
AFNKGEKKDTCTQEC	ITGB1	651	P05556
KCAEKEKTFCVNGGE	NRG1	181	Q02297
KAANCCEEVKELKAQ	ANGPTL7	41	O43827
CCLSIKSKLQKENGE	PARP8	101	Q8N3A8
KVAGDCLDEKQCKQC	LRRC59	126	Q96AG4
SGCKECEELEEKNIK	IL15	131	P40933
VSCCKGKKSVIEGVD	LMBRD1	511	Q9NUN5
CVKVQSIEGDNCKIE	FAM185A	161	Q8N0U4
FAVDGKDCKVNKEVE	GATD3B	146	A0A0B4J2D5
KCVDEPEKCTVCKEG	PCSK6	806	P29122
EEQKCKLGVATAGCV	IRF8	116	Q02556
GVTAKKEYVCQLCEK	NSD2	661	O96028
LKKEVGKILCTDCAT	NRG2	221	O14511
KAEITCKDNKDGTCT	FLNC	1901	Q14315
CKKLEESLTVEICGK	DGKA	571	P23743
VQDQEELCNGKCKSK	DEPDC1	491	Q5TB30
GKIAKDAKECVQECV	NFYB	76	P25208
EGKCIKAKSCEDIQC	FST	236	P19883
KQCKDGEAVKDTCKN	DEFB118	36	Q96PH6
KDCGNKEKCISDLSL	ITGA1	806	P56199
GEKKGRTCEECNFKV	ITGB4	641	P16144
QKSQVGGKRFECKDC	PEG3	496	Q9GZU2
DCCKIGVAQKSEIKE	HFM1	1156	A2PYH4
GEGEVINEKDRCKKC	DNAJA2	191	O60884
CVIDCNEKTGRKSQK	ERVK-5	111	Q9HDB9
KEIGSNKVEDKCGVC	ADAMTS3	691	O15072
CDNEKTGCKARELKS	CEP104	101	O60308
CKNKDDQGFESCEKV	ICE2	481	Q659A1
CQIKVFCDKGAERKI	GRHL2	411	Q6ISB3
EEFDNTCCAEKRKKL	KCNB1	161	Q14721
LSGKKQGCIEEQCKR	DOCK11	1871	Q5JSL3
KSCKGEKEIDDQKNC	BRCA2	3251	P51587
IKDKICLEKDNGCTE	CCDC73	516	Q6ZRK6
KFGSQKECEKVCAPV	COL6A3	3151	P12111
CNACGESVKKIQVEK	LYAR	6	Q9NX58
FAVDGKDCKVNKEVE	GATD3	146	P0DPI2
EVENNIKKKACCCEG	GEN1	311	Q17RS7
GTKDCLVQECKDLNK	DGKE	411	P52429
DGKTCKDLDECQTKQ	FBN2	2526	P35556
DVEIKKFLAGCLKCS	SASS6	146	Q6UVJ0
CELEVCAKCGKKEDI	C9orf85	91	Q96MD7
KECGKIQEALNCLVK	ERCC6L	1211	Q2NKX8
ECKDCGKAFIQKSNL	ZNF146	101	Q15072
QKENVFKCDSLKEEC	FAN1	211	Q9Y2M0
CDVKFESKERTACKG	RTKN2	86	Q8IZC4
VLCDSCIGNKQKAVK	TRIM29	171	Q14134
IDSDFLSKCENKCKV	GTF3C6	31	Q969F1
LSKCENKCKVLGIDT	GTF3C6	36	Q969F1
ADQVDKCYKCIVKQG	PHF2	296	O75151
CQENCKKTLTLIEKG	SYNE1	861	Q8NF91
KEKPFECDVQGCEKA	MTF1	196	Q14872
AGTKCDKVAQDLCKV	ETFA	56	P13804
GNALCTVKCDEKVKV	ETFA	151	P13804
VQKKDNKIFEISCCS	SIAE	431	Q9HAT2
EVIKSQEVFKDNCCK	TRAF5	86	O00463
KGDYTCCDLVVKIKE	C10orf90	511	Q96M02
KKEGILADCEKEACS	SLC7A14	451	Q8TBB6
LPVKCDACKQDFCKD	ZFAND2A	21	Q8N6M9
CEGIKKVVNVLACEK	THEMIS	401	Q8N1K5
KGEEDDKSKKQFVCI	WDR47	586	O94967
KVNCVKEEISRYCGK	TXNDC16	81	Q9P2K2
KGCKSVNECNVQKEG	ZNF738	146	Q8NE65
CQESIVKDKVFKDNC	TRAF3	91	Q13114
CNECGKAFREKSKLI	ZNF182	516	P17025
ECNECGKVFILKKSL	ZNF197	651	O14709
ECDECGKCFILKKSL	ZNF197	791	O14709
EKCETDEIQKGGKCR	USP45	171	Q70EL2
KACKVEDLGKVDFED	WDR48	391	Q8TAF3
ECKECGKAFSRKENL	ZNF568	251	Q3ZCX4
KIVLKVVKQCCGTDG	SF3B1	786	O75533
LKVDGQKNCCEEGKE	TUT1	661	Q9H6E5
EKKLKCTVEGCDRTF	ZNF410	216	Q86VK4
VRKFKCCQISIEEGK	SCN2A	1176	Q99250
EDLQVKKCCKSVGEC	ZNF716	121	A6NP11
CVLQGADCGAKVVEK	UAP1L1	271	Q3KQV9
KCEACDKVFGQKSAL	ZNF808	596	Q8N4W9
CLLKVGSKTEVAECK	GTF3C4	116	Q9UKN8
KVNFCKCEECEKAVN	ZNF675	196	Q8TD23
LQLKKGCISVDECKV	ZNF626	111	Q68DY1
KLKCDECGKEFSQGA	ZNF226	306	Q9NYT6
LQLRKGCKSVDECKV	ZNF726	111	A6NNF4
CEECGKVFKKNALLV	ZNF543	201	Q08ER8
TSKAEKAIECDECGK	ZFX	481	P17010
CCGLSEEKAIEVYKK	TXNRD3	526	Q86VQ6
SCNICGKKFEKKDSV	ZFP91	431	Q96JP5
TEEICQKITCKGFKV	ZMYM1	916	Q5SVZ6
FCITEKGVVKEEKNE	ZBTB38	136	Q8NAP3
ETKSDKKDCAAFAIC	TEX15	2446	Q9BXT5
KKDCAAFAICDQKSV	TEX15	2451	Q9BXT5
CGKEEKKEGDCRQTL	ZNF831	1361	Q5JPB2
KDESGQECKICRKII	ZNF674	116	Q2M3X9
EEKACECKICGKVFG	ZNF426	416	Q9BUY5
CNECEKAFIQKTKLV	ZNF34	421	Q8IZ26
LQLRKGCKSVDECKV	ZNF257	111	Q9Y2Q1
LQFKKGCESVDECKV	ZNF737	111	O75373
EGVKESLCAKEEKCQ	KCNA4	616	P22459