Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneuropeptide binding

NPBWR1 PRLHR GALR1 SSTR3 OPRK1 OPRL1 OPRM1

4.97e-1337387GO:0042923
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

NPBWR1 PRLHR GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

2.72e-12133389GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

NPBWR1 PRLHR GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

4.33e-12140389GO:0001653
GeneOntologyMolecularFunctionG protein-coupled opioid receptor activity

NPBWR1 OPRK1 OPRL1 OPRM1

3.89e-107384GO:0004985
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADGRG7 NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 GPR157 EDNRB OPRK1 OPRL1 OPRM1

4.45e-098843813GO:0004930
GeneOntologyMolecularFunctionneuropeptide receptor activity

NPBWR1 PRLHR GALR1 SSTR3 OPRM1

5.10e-0853385GO:0008188
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADGRG7 NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 GPR157 TNFRSF8 EDNRB OPRK1 OPRL1 OPRM1

8.31e-0813533814GO:0004888
GeneOntologyMolecularFunctionpeptide binding

NPBWR1 PRLHR GALR1 OXTR SSTR3 OPRK1 OPRL1 OPRM1

1.22e-07318388GO:0042277
GeneOntologyMolecularFunctionpeptide hormone binding

PRLHR GALR1 OXTR EDNRB

3.55e-0655384GO:0017046
GeneOntologyMolecularFunctionABC-type bile acid transporter activity

ABCC11 ABCC4

2.11e-054382GO:0015432
GeneOntologyMolecularFunctionATPase-coupled organic acid transmembrane transporter activity

ABCC11 ABCC4

2.11e-054382GO:0033283
GeneOntologyMolecularFunctionATPase-coupled monocarboxylic acid transmembrane transporter activity

ABCC11 ABCC4

2.11e-054382GO:0033285
GeneOntologyMolecularFunctionATPase-coupled carboxylic acid transmembrane transporter activity

ABCC11 ABCC4

2.11e-054382GO:0033284
GeneOntologyMolecularFunctionhormone binding

PRLHR GALR1 OXTR EDNRB

4.31e-05103384GO:0042562
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A10 SLC5A2

7.36e-057382GO:0005412
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ABCC11 KCNMB4 ABCC4 SLC5A10 CLCN1 CLDN17 SLC5A2 OPRM1

7.39e-05758388GO:0015318
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC11 ABCC4

9.80e-058382GO:0015431
GeneOntologyMolecularFunctiontransporter activity

TMEM184C ABCC11 GJC2 KCNMB4 ABCC4 SLC5A10 CLCN1 CLDN17 SLC5A2 OPRM1

1.08e-0412893810GO:0005215
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC11 ABCC4

1.26e-049382GO:0034040
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC11 ABCC4

1.57e-0410382GO:0043225
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC11 GJC2 KCNMB4 ABCC4 SLC5A10 CLCN1 CLDN17 SLC5A2 OPRM1

2.92e-041180389GO:0022857
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC11 ABCC4 CLCN1 CLDN17

3.05e-04171384GO:0015103
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC11 ABCC4

3.65e-0415382GO:0008559
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A10 SLC5A2

4.71e-0417382GO:0005402
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC5A10 SLC5A2

1.03e-0325382GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC5A10 SLC5A2

1.03e-0325382GO:0015149
GeneOntologyMolecularFunctionprotein-cysteine S-palmitoyltransferase activity

ZDHHC20 ZDHHC16

1.11e-0326382GO:0019706
GeneOntologyMolecularFunctionprotein-cysteine S-acyltransferase activity

ZDHHC20 ZDHHC16

1.11e-0326382GO:0019707
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC5A10 SLC5A2

1.20e-0327382GO:0015145
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

ABCC11 ABCC4

1.39e-0329382GO:0015216
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC5A10 SLC5A2

1.39e-0329382GO:0051119
GeneOntologyMolecularFunctionS-acyltransferase activity

ZDHHC20 ZDHHC16

1.48e-0330382GO:0016417
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

ABCC11 ABCC4

1.79e-0333382GO:0015215
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

ABCC11 ABCC4

1.90e-0334382GO:0015125
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC11 ABCC4

1.90e-0334382GO:0042910
GeneOntologyMolecularFunctionpalmitoyltransferase activity

ZDHHC20 ZDHHC16

2.25e-0337382GO:0016409
GeneOntologyMolecularFunctionamide binding

PRLHR GALR1 OXTR EDNRB

2.44e-03299384GO:0033218
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

ABCC11 ABCC4

2.50e-0339382GO:0015605
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC5A10 SLC5A2

2.89e-0342382GO:0015144
GeneOntologyMolecularFunctionchannel activity

GJC2 KCNMB4 CLCN1 CLDN17 OPRM1

3.02e-03525385GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GJC2 KCNMB4 CLCN1 CLDN17 OPRM1

3.05e-03526385GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

KCNMB4 SLC5A10 CLCN1 CLDN17 SLC5A2 OPRM1

3.59e-03793386GO:0015075
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC11 ABCC4

3.92e-0349382GO:0140359
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNMB4 CLCN1 OPRM1

4.97e-03182383GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNMB4 CLCN1 OPRM1

5.12e-03184383GO:0022832
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

ABCC11 ABCC4

5.64e-0359382GO:0015932
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC11 ABCC4

6.01e-0361382GO:1901682
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCC11 ABCC4

7.85e-0370382GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC11 ABCC4

8.51e-0373382GO:0170055
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A10 SLC5A2

1.04e-0281382GO:0015370
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNMB4 CLCN1 CLDN17 OPRM1

1.10e-02459384GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNMB4 SLC5A10 SLC5A2 OPRM1

1.15e-02465384GO:0046873
GeneOntologyMolecularFunctionchloride channel activity

CLCN1 CLDN17

1.17e-0286382GO:0005254
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC11 ABCC4 SLC5A10 SLC5A2

1.25e-02477384GO:0022804
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC11 ABCC4

1.27e-0290382GO:0008028
GeneOntologyMolecularFunctionmonoatomic anion channel activity

CLCN1 CLDN17

1.64e-02103382GO:0005253
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC11 ABCC4

1.83e-02109382GO:0042626
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A10 SLC5A2

2.15e-02119382GO:0015294
GeneOntologyBiologicalProcessneuropeptide signaling pathway

NPBWR1 PRLHR GALR1 SSTR3 OPRK1 OPRL1 OPRM1

2.12e-09124377GO:0007218
GeneOntologyBiologicalProcessG protein-coupled opioid receptor signaling pathway

NPBWR1 OPRK1 OPRL1 OPRM1

6.19e-0913374GO:0038003
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

ADGRG7 GALR1 GPR101 P2RY1 GPR157 OPRK1 OPRL1 OPRM1

3.38e-08286378GO:0007188
GeneOntologyBiologicalProcesseating behavior

OXTR P2RY1 OPRK1 OPRL1 OPRM1

5.01e-0856375GO:0042755
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

P2RY1 GPR157 EDNRB OPRK1 OPRL1 OPRM1

1.27e-07133376GO:0007200
GeneOntologyBiologicalProcesscopulation

OXTR P2RY1 EDNRB OPRM1

1.49e-0727374GO:0007620
GeneOntologyBiologicalProcessreproductive behavior

OXTR P2RY1 EDNRB OPRK1 OPRM1

2.07e-0774375GO:0019098
GeneOntologyBiologicalProcessfeeding behavior

PRLHR OXTR P2RY1 OPRK1 OPRL1 OPRM1

4.07e-07162376GO:0007631
GeneOntologyBiologicalProcesspositive regulation of penile erection

OXTR P2RY1 EDNRB

4.43e-079373GO:0060406
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

ADGRG7 NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 GPR157 EDNRB OPRK1 OPRL1 OPRM1

4.50e-0713953713GO:0007186
GeneOntologyBiologicalProcessregulation of penile erection

OXTR P2RY1 EDNRB

8.68e-0711373GO:0060405
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

ADGRG7 GALR1 GPR101 GPR157 OPRL1 OPRM1

1.07e-06191376GO:0007189
GeneOntologyBiologicalProcesspenile erection

OXTR P2RY1 EDNRB

1.16e-0612373GO:0043084
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ABCC11 GJC2 KCNMB4 ABCC4 SLC5A10 CLCN1 CLDN17 EDNRB OPRK1 SLC5A2 OPRM1

2.55e-0611153711GO:0034220
GeneOntologyBiologicalProcessendocrine process

GALR1 OXTR EDNRB OPRK1 OPRM1

2.60e-06123375GO:0050886
GeneOntologyBiologicalProcessmonoatomic ion transport

ABCC11 GJC2 KCNMB4 ABCC4 SLC5A10 CLCN1 P2RY1 CLDN17 EDNRB OPRK1 SLC5A2 OPRM1

2.82e-0613743712GO:0006811
GeneOntologyBiologicalProcessmating behavior

OXTR P2RY1 EDNRB OPRM1

3.23e-0657374GO:0007617
GeneOntologyBiologicalProcessestrous cycle

OXTR OPRK1 OPRL1

5.93e-0620373GO:0044849
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting opioid receptor signaling pathway

OPRK1 OPRM1

9.38e-063372GO:0031635
GeneOntologyBiologicalProcesssignal release

KCNMB4 ABCC4 GALR1 OXTR P2RY1 EDNRB OPRK1 OPRM1

1.66e-05653378GO:0023061
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

P2RY1 OPRK1 OPRL1 OPRM1

1.67e-0586374GO:0007193
GeneOntologyBiologicalProcessregulation of urine volume

EDNRB OPRL1 SLC5A2

2.09e-0530373GO:0035809
GeneOntologyBiologicalProcessorganic hydroxy compound transport

ABCC11 ABCC4 GALR1 OXTR P2RY1 OPRK1

3.87e-05358376GO:0015850
GeneOntologyBiologicalProcessnegative regulation of luteinizing hormone secretion

OPRK1 OPRM1

4.68e-056372GO:0033685
GeneOntologyBiologicalProcessconditioned place preference

OPRK1 OPRL1

4.68e-056372GO:1990708
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

GALR1 OXTR P2RY1 EDNRB OPRM1

4.74e-05224375GO:0007204
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GJC2 KCNMB4 SLC5A10 CLCN1 CLDN17 EDNRB OPRK1 SLC5A2 OPRM1

5.92e-051017379GO:0098660
GeneOntologyBiologicalProcesssperm ejaculation

OXTR OPRM1

6.54e-057372GO:0042713
GeneOntologyBiologicalProcessleukotriene transport

ABCC11 ABCC4

6.54e-057372GO:0071716
GeneOntologyBiologicalProcessregulation of body fluid levels

OXTR P2RY1 EDNRB OPRK1 OPRL1 SLC5A2

1.24e-04442376GO:0050878
GeneOntologyBiologicalProcessregulation of luteinizing hormone secretion

OPRK1 OPRM1

1.40e-0410372GO:0033684
GeneOntologyBiologicalProcessbehavior

PRLHR OXTR P2RY1 GPR157 EDNRB OPRK1 OPRL1 OPRM1

1.49e-04891378GO:0007610
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

ABCC11 ABCC4 CLCN1 CLDN17

1.59e-04153374GO:0098656
GeneOntologyBiologicalProcessnegative regulation of gonadotropin secretion

OPRK1 OPRM1

1.70e-0411372GO:0032277
GeneOntologyBiologicalProcessregulation of endocrine process

GALR1 OPRK1 OPRM1

1.78e-0461373GO:0044060
GeneOntologyBiologicalProcessregulation of catecholamine secretion

OXTR P2RY1 OPRK1

2.35e-0467373GO:0050433
GeneOntologyBiologicalProcessluteinizing hormone secretion

OPRK1 OPRM1

2.81e-0414372GO:0032275
GeneOntologyBiologicalProcessnegative regulation of cAMP-mediated signaling

OPRL1 OPRM1

2.81e-0414372GO:0043951
GeneOntologyBiologicalProcessmonoatomic anion transport

ABCC11 ABCC4 CLCN1 CLDN17

3.15e-04183374GO:0006820
GeneOntologyBiologicalProcesspositive regulation of urine volume

EDNRB OPRL1

3.24e-0415372GO:0035810
GeneOntologyBiologicalProcessvascular process in circulatory system

KCNMB4 ABCC4 OXTR P2RY1 EDNRB

3.52e-04344375GO:0003018
GeneOntologyBiologicalProcessendocrine hormone secretion

GALR1 OPRK1 OPRM1

3.55e-0477373GO:0060986
GeneOntologyBiologicalProcessinsemination

OXTR OPRM1

3.70e-0416372GO:0007320
GeneOntologyBiologicalProcessregulation of gonadotropin secretion

OPRK1 OPRM1

3.70e-0416372GO:0032276
GeneOntologyBiologicalProcesscatecholamine secretion

OXTR P2RY1 OPRK1

3.83e-0479373GO:0050432
GeneOntologyBiologicalProcessblood vessel diameter maintenance

KCNMB4 OXTR P2RY1 EDNRB

4.58e-04202374GO:0097746
GeneOntologyBiologicalProcessregulation of tube diameter

KCNMB4 OXTR P2RY1 EDNRB

4.58e-04202374GO:0035296
GeneOntologyBiologicalProcessregulation of tube size

KCNMB4 OXTR P2RY1 EDNRB

4.66e-04203374GO:0035150
GeneOntologyBiologicalProcessmaternal behavior

OXTR OPRK1

4.70e-0418372GO:0042711
GeneOntologyBiologicalProcessnegative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

OPRL1 OPRM1

4.70e-0418372GO:0106072
GeneOntologyBiologicalProcessnegative regulation of adenylate cyclase activity

GALR1 EDNRB

4.70e-0418372GO:0007194
GeneOntologyBiologicalProcesssecretion by cell

KCNMB4 ABCC4 GALR1 OXTR P2RY1 EDNRB OPRK1 OPRM1

4.95e-041064378GO:0032940
GeneOntologyBiologicalProcesspositive regulation of catecholamine secretion

OXTR OPRK1

5.25e-0419372GO:0033605
GeneOntologyBiologicalProcessnegative regulation of cyclase activity

GALR1 EDNRB

5.25e-0419372GO:0031280
GeneOntologyBiologicalProcessparental behavior

OXTR OPRK1

6.44e-0421372GO:0060746
GeneOntologyBiologicalProcessovulation cycle

OXTR OPRK1 OPRL1

6.57e-0495373GO:0042698
GeneOntologyBiologicalProcesscatecholamine transport

OXTR P2RY1 OPRK1

6.77e-0496373GO:0051937
GeneOntologyBiologicalProcessgonadotropin secretion

OPRK1 OPRM1

7.07e-0422372GO:0032274
GeneOntologyBiologicalProcessnegative regulation of lyase activity

GALR1 EDNRB

7.07e-0422372GO:0051350
GeneOntologyBiologicalProcessrenal tubular secretion

EDNRB SLC5A2

7.74e-0423372GO:0097254
GeneOntologyBiologicalProcessexport from cell

KCNMB4 ABCC4 GALR1 OXTR P2RY1 EDNRB OPRK1 OPRM1

8.40e-041153378GO:0140352
GeneOntologyBiologicalProcesssensory perception of pain

OPRK1 OPRL1 OPRM1

8.78e-04105373GO:0019233
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

OXTR P2RY1

9.90e-0426372GO:0014061
GeneOntologyBiologicalProcessregulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

OPRL1 OPRM1

9.90e-0426372GO:0106070
GeneOntologyBiologicalProcesstransmission of nerve impulse

KCNMB4 CLCN1 OPRM1

1.06e-03112373GO:0019226
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

GJC2 KCNMB4 SLC5A10 EDNRB OPRK1 SLC5A2 OPRM1

1.11e-03922377GO:0098662
GeneOntologyBiologicalProcessnorepinephrine secretion

OXTR P2RY1

1.15e-0328372GO:0048243
GeneOntologyBiologicalProcessmonoamine transport

OXTR P2RY1 OPRK1

1.17e-03116373GO:0015844
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

NPBWR1 KCNMB4 OXTR P2RY1 OPRK1 OPRL1 OPRM1

1.17e-03931377GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

NPBWR1 KCNMB4 OXTR P2RY1 OPRK1 OPRL1 OPRM1

1.17e-03931377GO:0007268
GeneOntologyBiologicalProcesssecretion

KCNMB4 ABCC4 GALR1 OXTR P2RY1 EDNRB OPRK1 OPRM1

1.22e-031221378GO:0046903
GeneOntologyBiologicalProcesspositive regulation of reproductive process

OXTR P2RY1 EDNRB

1.23e-03118373GO:2000243
GeneOntologyBiologicalProcesstrans-synaptic signaling

NPBWR1 KCNMB4 OXTR P2RY1 OPRK1 OPRL1 OPRM1

1.23e-03939377GO:0099537
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

GJC2 KCNMB4 SLC5A10 EDNRB OPRK1 SLC5A2 OPRM1

1.25e-03942377GO:0098655
GeneOntologyBiologicalProcessregulation of hormone levels

PRLHR GALR1 P2RY1 EDNRB OPRK1 OPRM1

1.26e-03684376GO:0010817
GeneOntologyBiologicalProcessvasoconstriction

KCNMB4 OXTR EDNRB

1.32e-03121373GO:0042310
GeneOntologyBiologicalProcessregulation of amine transport

OXTR P2RY1 OPRK1

1.45e-03125373GO:0051952
GeneOntologyBiologicalProcessresponse to alkaloid

OXTR OPRK1 OPRM1

1.45e-03125373GO:0043279
GeneOntologyBiologicalProcesssynaptic signaling

NPBWR1 KCNMB4 OXTR P2RY1 OPRK1 OPRL1 OPRM1

1.54e-03976377GO:0099536
GeneOntologyBiologicalProcessresponse to estradiol

OXTR SSTR3 OPRL1

1.55e-03128373GO:0032355
GeneOntologyBiologicalProcessprotein palmitoylation

ZDHHC20 ZDHHC16

1.60e-0333372GO:0018345
GeneOntologyBiologicalProcessmetal ion transport

GJC2 KCNMB4 SLC5A10 EDNRB OPRK1 SLC5A2 OPRM1

1.77e-031000377GO:0030001
GeneOntologyBiologicalProcesscirculatory system process

KCNMB4 ABCC4 OXTR P2RY1 EDNRB OPRL1

1.79e-03733376GO:0003013
GeneOntologyBiologicalProcessregulation of system process

KCNMB4 GALR1 OXTR EDNRB OPRK1 OPRM1

1.80e-03734376GO:0044057
GeneOntologyBiologicalProcessregulation of secretion by cell

KCNMB4 GALR1 OXTR P2RY1 OPRK1 OPRM1

1.88e-03740376GO:1903530
GeneOntologyBiologicalProcessamine transport

OXTR P2RY1 OPRK1

1.89e-03137373GO:0015837
GeneOntologyBiologicalProcessexcretion

EDNRB SLC5A2

2.00e-0337372GO:0007588
GeneOntologyBiologicalProcessnorepinephrine transport

OXTR P2RY1

2.11e-0338372GO:0015874
GeneOntologyBiologicalProcessresponse to organic cyclic compound

OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

2.31e-031048377GO:0014070
GeneOntologyBiologicalProcessregulation of cAMP-mediated signaling

OPRL1 OPRM1

2.34e-0340372GO:0043949
GeneOntologyBiologicalProcessrenal system process

EDNRB OPRL1 SLC5A2

2.40e-03149373GO:0003014
GeneOntologyBiologicalProcessregulation of secretion

KCNMB4 GALR1 OXTR P2RY1 OPRK1 OPRM1

2.79e-03801376GO:0051046
GeneOntologyBiologicalProcesspurine nucleotide transport

ABCC11 ABCC4

2.82e-0344372GO:0015865
GeneOntologyBiologicalProcessrenal absorption

EDNRB SLC5A2

2.95e-0345372GO:0070293
GeneOntologyBiologicalProcessbile acid and bile salt transport

ABCC11 ABCC4

3.22e-0347372GO:0015721
GeneOntologyCellularComponentapical plasma membrane

ABCC11 ABCC4 SLC5A10 OXTR P2RY1 USH2A SLC5A2

2.41e-05487387GO:0016324
GeneOntologyCellularComponentapical part of cell

ABCC11 ABCC4 SLC5A10 OXTR P2RY1 USH2A SLC5A2

8.29e-05592387GO:0045177
GeneOntologyCellularComponentphotoreceptor connecting cilium

KIAA1549 TMEM237 USH2A

9.06e-0548383GO:0032391
GeneOntologyCellularComponentcilium

KIAA1549 ABCC4 PRLHR SSTR3 P2RY1 TMEM237 USH2A GPR157

1.74e-04898388GO:0005929
GeneOntologyCellularComponentciliary transition zone

KIAA1549 TMEM237 USH2A

4.29e-0481383GO:0035869
GeneOntologyCellularComponentnon-motile cilium

KIAA1549 SSTR3 TMEM237 USH2A

4.31e-04196384GO:0097730
GeneOntologyCellularComponentcell projection membrane

SSTR3 USH2A GPR157 SLC5A2 OPRM1

1.04e-03431385GO:0031253
GeneOntologyCellularComponentphotoreceptor cell cilium

KIAA1549 TMEM237 USH2A

2.05e-03139383GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

KIAA1549 TMEM237 USH2A

2.69e-03153383GO:0097731
MousePhenoabnormal chemically-elicited antinociception

PRLHR OPRK1 OPRL1 OPRM1

4.52e-0729314MP:0001980
MousePhenoimpaired behavioral response to morphine

OPRK1 OPRL1 OPRM1

1.17e-0610313MP:0009757
MousePhenoabnormal behavioral response to morphine

OPRK1 OPRL1 OPRM1

2.78e-0613313MP:0020159
MousePhenodecreased chemically-elicited antinociception

OPRK1 OPRL1 OPRM1

9.34e-0619313MP:0001982
MousePhenoabnormal pain threshold

ABCC4 PRLHR EDNRB OPRK1 OPRL1 OPRM1

2.26e-05267316MP:0001970
MousePhenoimpaired behavioral response to anesthetic

OPRK1 OPRM1

4.74e-055312MP:0009778
MousePhenoabnormal conditioned place preference behavior

PRLHR GALR1 OPRM1

6.16e-0535313MP:0009711
MousePhenoabnormal behavioral response to addictive substance

PRLHR OPRK1 OPRL1 OPRM1

7.23e-05102314MP:0009748
MousePhenoimpaired behavioral response to addictive substance

OPRK1 OPRL1 OPRM1

1.32e-0445313MP:0009750
MousePhenoincreased chemically-elicited antinociception

PRLHR OPRM1

1.32e-048312MP:0001981
MousePhenoabnormal touch/ nociception

ABCC4 PRLHR EDNRB OPRK1 OPRL1 OPRM1

1.52e-04376316MP:0001968
MousePhenodecreased behavioral withdrawal response

PRLHR OPRM1

1.70e-049312MP:0009776
MousePhenoabnormal associative learning

PRLHR GALR1 OXTR OPRK1 OPRL1 OPRM1

1.93e-04393316MP:0002062
MousePhenoabnormal gastrointestinal motility

ADGRG7 EDNRB OPRM1

2.03e-0452313MP:0011082
MousePhenoenhanced conditioned place preference behavior

PRLHR OPRM1

2.12e-0410312MP:0009713
MousePhenoabnormal learning/memory/conditioning

KIAA1549 GJC2 PRLHR GALR1 CLCN1 OXTR PARP8 OPRK1 OPRL1 OPRM1

2.26e-0412393110MP:0002063
MousePhenoabnormal cognition

KIAA1549 GJC2 PRLHR GALR1 CLCN1 OXTR PARP8 OPRK1 OPRL1 OPRM1

2.37e-0412463110MP:0014114
MousePhenoabnormal digestive system physiology

ADGRG7 ABCC4 CLDN17 EDNRB OPRK1 SLC5A2 OPRM1

2.74e-04599317MP:0001663
MousePhenoabnormal behavioral withdrawal response

PRLHR OPRM1

3.10e-0412312MP:0009774
MousePhenoabnormal behavioral response to anesthetic

OPRK1 OPRM1

3.10e-0412312MP:0009777
MousePhenoincreased circulating insulin level

NPBWR1 PRLHR SLC5A10 STOML2 OPRM1

3.62e-04283315MP:0002079
MousePhenoabnormal thermal nociception

ABCC4 PRLHR OPRL1 OPRM1

4.92e-04168314MP:0002733
MousePhenohypoalgesia

ABCC4 PRLHR EDNRB OPRM1

5.14e-04170314MP:0003043
MousePhenoabnormal circulating insulin level

NPBWR1 PRLHR SLC5A10 STOML2 SLC5A2 OPRM1

7.35e-04505316MP:0001560
MousePhenoimpaired behavioral response to xenobiotic

OPRK1 OPRL1 OPRM1

8.05e-0483313MP:0009747
MousePhenoenhanced fertility

CD46 OPRK1

8.82e-0420312MP:0010143
MousePhenoincreased litter size

CD46 OPRK1

8.82e-0420312MP:0001934
MousePhenoincreased circulating chloride level

TMEM237 CLDN17 SLC5A2

1.26e-0397313MP:0003019
MousePhenoimpaired conditioned place preference behavior

GALR1 OPRM1

1.50e-0326312MP:0009712
DomainGPCR_Rhodpsn_7TM

NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 GPR157 EDNRB OPRK1 OPRL1 OPRM1

4.74e-096703812IPR017452
DomainOpioid_rcpt

OPRK1 OPRL1 OPRM1

3.10e-084383IPR001418
Domain7tm_1

NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

6.45e-086773811PF00001
DomainG_PROTEIN_RECEP_F1_1

NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

7.26e-086853811PS00237
DomainG_PROTEIN_RECEP_F1_2

NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

7.94e-086913811PS50262
DomainGPCR_Rhodpsn

NPBWR1 PRLHR GALR1 OXTR GPR101 SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

8.05e-086923811IPR000276
Domain7TM_GPCR_Srsx

PRLHR GALR1 SSTR3 EDNRB OPRK1 OPRL1

9.59e-08112386SM01381
DomainDUF3827

KIAA1549 KIAA1549L

4.03e-062382IPR024606
DomainDUF3827

KIAA1549 KIAA1549L

4.03e-062382PF12877
DomainNa/solute_symporter_CS

SLC5A10 SLC5A2

1.12e-048382IPR018212
DomainSSF

SLC5A10 SLC5A2

2.63e-0412382PF00474
DomainNa/solute_symporter

SLC5A10 SLC5A2

2.63e-0412382IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A10 SLC5A2

2.63e-0412382PS50283
DomainNA_SOLUT_SYMP_2

SLC5A10 SLC5A2

2.63e-0412382PS00457
Domainzf-DHHC

ZDHHC20 ZDHHC16

9.93e-0423382PF01529
DomainABC_membrane

ABCC11 ABCC4

1.08e-0324382PF00664
DomainDHHC

ZDHHC20 ZDHHC16

1.17e-0325382PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC20 ZDHHC16

1.17e-0325382IPR001594
DomainABC_TM1F

ABCC11 ABCC4

1.47e-0328382PS50929
DomainABC1_TM_dom

ABCC11 ABCC4

1.47e-0328382IPR011527
DomainABC_transporter_CS

ABCC11 ABCC4

3.30e-0342382IPR017871
DomainABC_TRANSPORTER_2

ABCC11 ABCC4

4.29e-0348382PS50893
DomainABC_tran

ABCC11 ABCC4

4.29e-0348382PF00005
DomainABC_TRANSPORTER_1

ABCC11 ABCC4

4.46e-0349382PS00211
Domain7tm_2

ADGRG7 GPR157

4.64e-0350382PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRG7 GPR157

4.64e-0350382PS00650
DomainABC_transporter-like

ABCC11 ABCC4

4.64e-0350382IPR003439
DomainGPCR_2-like

ADGRG7 GPR157

6.62e-0360382IPR017981
DomainGPCR_2_secretin-like

ADGRG7 GPR157

6.62e-0360382IPR000832
DomainG_PROTEIN_RECEP_F2_4

ADGRG7 GPR157

6.84e-0361382PS50261
PathwayWP_GPCRS_PEPTIDE

GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

2.11e-1070337MM15959
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

2.44e-102603310M39397
PathwayWP_PEPTIDE_GPCRS

GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

3.47e-1075337M39696
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

3.80e-102723310M13380
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

NPBWR1 PRLHR GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

4.89e-10197339M12289
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

NPBWR1 PRLHR GALR1 OXTR SSTR3 EDNRB OPRK1 OPRL1 OPRM1

4.89e-10197339MM14970
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

2.48e-093303310M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

2.70e-093333310MM14963
PathwayWP_GPCRS_NONODORANT

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRM1

6.88e-09266339MM15843
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

8.27e-09186338MM15994
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

3.10e-084303310MM15160
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

6.22e-084633310M507
PathwayREACTOME_SIGNALING_BY_GPCR

DAGLB NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

1.32e-076463311MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

DAGLB NPBWR1 PRLHR GALR1 OXTR SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

3.06e-077023311M746
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

NPBWR1 GALR1 SSTR3 OPRK1 OPRL1 OPRM1

4.90e-05289336MM15057
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

NPBWR1 GALR1 SSTR3 OPRK1 OPRL1 OPRM1

7.76e-05314336M600
PathwayWP_GPCRS_ODORANT

ADGRG7 GPR101 GPR157 OPRL1

4.71e-04157334MM15872
PathwayREACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS

OPRK1 OPRM1

7.94e-0418332M27901
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC5A10 SLC5A2

8.86e-0419332MM14718
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC5A10 SLC5A2

1.09e-0321332M27058
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

DAGLB OXTR P2RY1 EDNRB

1.40e-03210334MM15043
PathwayWP_GPCRS_OTHER

OPRK1 OPRL1 OPRM1

1.44e-0396333MM15939
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

DAGLB OXTR P2RY1 EDNRB

1.57e-03217334M18437
Pubmed

Dissociation of heterotrimeric g proteins in cells.

NPBWR1 GALR1 SSTR3 P2RY1 EDNRB OPRK1 OPRL1 OPRM1

1.80e-1117938818577758
Pubmed

Multiple opioid receptor-like genes are identified in diverse vertebrate phyla.

OPRK1 OPRL1 OPRM1

4.81e-0943838941707
Pubmed

Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene.

OPRK1 OPRL1 OPRM1

4.81e-09438311430857
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GALR1 SSTR3 OPRK1 OPRL1 OPRM1

2.86e-088138522723691
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

NPBWR1 SSTR3 P2RY1 OPRK1 OPRL1 OPRM1

7.94e-0820038618240029
Pubmed

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

GALR1 EDNRB OPRL1 OPRM1

1.45e-074338423597562
Pubmed

Identification of a novel family of G protein-coupled receptor associated sorting proteins.

OPRK1 OPRL1 OPRM1

4.34e-071438315086532
Pubmed

Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.

OPRL1 OPRM1

1.16e-06238223652222
Pubmed

Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C).

OPRK1 OPRL1

1.16e-0623827802669
Pubmed

Differential stability of the crystallographic interfaces of mu- and kappa-opioid receptors.

OPRK1 OPRM1

1.16e-06238224651466
Pubmed

κ Opioid Receptor 1 Single Nucleotide Polymorphisms were Associated with the Methadone Dosage.

OPRK1 OPRM1

1.16e-06238231940240
Pubmed

Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist.

OPRL1 OPRM1

1.16e-06238215748148
Pubmed

Differential involvement of the mu and kappa opioid receptors in spatial learning.

OPRK1 OPRM1

1.16e-06238212884965
Pubmed

Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors.

OPRK1 OPRM1

1.16e-06238216530171
Pubmed

Involvement of µ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice.

OPRK1 OPRM1

1.16e-06238228512665
Pubmed

Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease.

OPRL1 OPRM1

1.16e-06238230152845
Pubmed

Association of OPRK1 and OPRM1 methylation with mild cognitive impairment in Xinjiang Han and Uygur populations.

OPRK1 OPRM1

1.16e-06238227838450
Pubmed

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

GALR1 OPRM1

1.16e-06238228007761
Pubmed

Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo-optico-neuropathy (SMON).

ABCC11 ABCC4

1.16e-06238234951141
Pubmed

Epistatic effects between variants of kappa-opioid receptor gene and A118G of mu-opioid receptor gene increase susceptibility to addiction in Indian population.

OPRK1 OPRM1

1.16e-06238222138325
Pubmed

Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors.

OPRK1 OPRM1

1.16e-06238216954126
Pubmed

Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11.

ABCC11 ABCC4

1.16e-06238212133003
Pubmed

Opioid Receptors in Psoriatic Skin: Relationship with Itch.

OPRK1 OPRM1

1.16e-06238227958613
Pubmed

Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior.

OPRK1 OPRM1

1.16e-06238217185983
Pubmed

Ligand directed signaling differences between rodent and human κ-opioid receptors.

OPRK1 OPRM1

1.16e-06238223086943
Pubmed

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.

PRLHR SSTR3 P2RY1

2.72e-062538328154160
Pubmed

Modelling the PKPD of oxycodone in experimental pain - Impact of opioid receptor polymorphisms.

OPRK1 OPRM1

3.48e-06338226946441
Pubmed

Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*.

OPRK1 OPRM1

3.48e-06338219032295
Pubmed

OPRM1, OPRK1, and COMT genetic polymorphisms associated with opioid effects on experimental pain: a randomized, double-blind, placebo-controlled study.

OPRK1 OPRM1

3.48e-06338231806881
Pubmed

Nociception increases during opioid infusion in opioid receptor triple knock-out mice.

OPRK1 OPRM1

3.48e-06338217544222
Pubmed

The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice.

OPRK1 OPRM1

3.48e-06338215090050
Pubmed

Endogenous opioid receptor genes and alcohol dependence among Taiwanese Han.

OPRK1 OPRM1

3.48e-06338214745298
Pubmed

Scanning of five chromosomes for alcohol consumption loci.

OPRK1 OPRL1

3.48e-06338211109025
Pubmed

Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

OPRK1 OPRM1

3.48e-0633828114680
Pubmed

Opioid receptor characterisation of neuronally stimulated isolated human vas deferens.

OPRK1 OPRM1

3.48e-06338222752269
Pubmed

Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice.

OPRK1 OPRM1

3.48e-06338211032994
Pubmed

Quantitative autoradiography of mu-,delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice.

OPRK1 OPRM1

3.48e-06338210082819
Pubmed

Systemic morphine treatment derails normal uterine receptivity, leading to embryo implantation failure in mice.

OPRK1 OPRM1

3.48e-06338225855262
Pubmed

Cell-specific actions of HIV-Tat and morphine on opioid receptor expression in glia.

OPRK1 OPRM1

3.48e-06338218338799
Pubmed

Opioid receptors: from binding sites to visible molecules in vivo.

OPRK1 OPRM1

3.48e-06338218718480
Pubmed

Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers.

OPRK1 OPRM1

3.48e-06338218537939
Pubmed

Food reward-sensitive interaction of ghrelin and opioid receptor pathways in mesolimbic dopamine system.

OPRK1 OPRM1

3.48e-06338223220294
Pubmed

Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones.

OPRK1 OPRM1

3.48e-06338212603260
Pubmed

Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice.

OPRK1 OPRM1

3.48e-06338217676326
Pubmed

Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence.

OPRK1 OPRM1

3.48e-06338224874714
Pubmed

Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.

EDNRB SLC5A2

3.48e-06338238747277
Pubmed

Searching for evidence of genetic mediation of opioid withdrawal by opioid receptor gene polymorphisms.

OPRK1 OPRM1

3.48e-06338226692286
Pubmed

Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study.

OPRK1 OPRM1

3.48e-06338217374034
Pubmed

Genetic Variations of OPRM1, OPRK1, and COMT Genes and Their Possible Associations with Oral Pain in a Population from Argentina.

OPRK1 OPRM1

3.48e-06338230365572
Pubmed

Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.

OPRK1 OPRM1

3.48e-06338211826143
Pubmed

Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations.

OPRK1 OPRM1

3.48e-06338218213616
Pubmed

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.

OPRK1 OPRM1

3.48e-06338233555255
Pubmed

Enhanced humoral response in kappa-opioid receptor knockout mice.

OPRK1 OPRM1

3.48e-06338212507774
Pubmed

Neurofilament proteins and cAMP pathway in brains of mu-, delta- or kappa-opioid receptor gene knock-out mice: effects of chronic morphine administration.

OPRK1 OPRM1

3.48e-06338214975676
Pubmed

Quantitative trait loci influencing morphine antinociception in four mapping populations.

OPRK1 OPRM1

3.48e-06338211420618
Pubmed

Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity.

OPRK1 OPRM1

3.48e-06338211504820
Pubmed

No evidence for G-protein-coupled epsilon receptor in the brain of triple opioid receptor knockout mouse.

OPRK1 OPRM1

3.48e-06338215178356
Pubmed

Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice.

OPRK1 OPRM1

3.48e-06338212431223
Pubmed

Differential coupling of mu-, delta-, and kappa-opioid receptors to G alpha16-mediated stimulation of phospholipase C.

OPRK1 OPRM1

3.48e-0633829572309
Pubmed

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation.

OPRK1 OPRM1

3.48e-06338228049031
Pubmed

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy.

OPRK1 OPRM1

3.48e-06338211069979
Pubmed

Formalin-induced pain is reduced in sigma(1) receptor knockout mice.

OPRK1 OPRM1

3.48e-06338215777781
Pubmed

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.

GJC2 GALR1 OXTR

4.79e-063038327568567
Pubmed

Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia.

OPRK1 OPRM1

6.96e-06438217997230
Pubmed

Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells.

OPRK1 OPRM1

6.96e-06438216053916
Pubmed

Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells.

OPRK1 OPRM1

6.96e-06438212413885
Pubmed

Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse.

OPRK1 OPRM1

6.96e-0643829502813
Pubmed

A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.

OPRK1 OPRM1

6.96e-06438230249798
Pubmed

Examining gene-environment interactions in comorbid depressive and disruptive behavior disorders using a Bayesian approach.

OXTR OPRM1

1.16e-05538226228411
Pubmed

Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling.

OPRK1 OPRM1

1.16e-05538220534436
Pubmed

Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms.

OPRK1 OPRM1

1.16e-05538233782947
Pubmed

Variations in opioid receptor genes in neonatal abstinence syndrome.

OPRK1 OPRM1

1.16e-05538226233486
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

CD46 TMEM237 TNFRSF8 MPZL1

1.32e-0513238426439863
Pubmed

Expression of opioid receptors and ligands in pregnant mouse uterus and placenta.

OPRK1 OPRM1

1.74e-0563829746745
Pubmed

Genetic susceptibility to heroin addiction: a candidate gene association study.

OPRK1 OPRM1

1.74e-05638218518925
Pubmed

Evidence of efficient stop codon readthrough in four mammalian genes.

OPRK1 OPRL1

1.74e-05638225013167
Pubmed

Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development.

OPRK1 OPRM1

1.74e-05638212044478
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GALR1 OXTR SSTR3 OPRK1 OPRM1

1.84e-0530038519086053
Pubmed

Preimplantation mouse embryo is a target for opioid ligand-receptor signaling.

OPRK1 OPRM1

3.24e-05838224855103
Pubmed

Misreading of termination codons in eukaryotes by natural nonsense suppressor tRNAs.

OPRK1 OPRL1

4.16e-05938211726686
Pubmed

Murine chromosomal location of the mu and kappa opioid receptor genes.

OPRK1 OPRM1

4.16e-0593827959748
Pubmed

Chromosomal localization of opioid peptide and receptor genes in the mouse.

OPRK1 OPRM1

7.62e-05123827752808
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

GALR1 SSTR3 OPRL1

7.70e-05753832834384
Pubmed

MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens.

OPRK1 OPRM1

1.21e-041538223840749
Pubmed

Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.

PRLHR SSTR3

1.21e-041538226053317
Pubmed

Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.

ZDHHC20 ZDHHC16

1.38e-041638223034182
Pubmed

A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases.

OPRK1 OPRM1

1.56e-041738221483469
Pubmed

Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon.

OPRK1 OPRM1

2.65e-042238211124115
Pubmed

A common variant in DRD3 receptor is associated with autism spectrum disorder.

OPRK1 OPRL1 OPRM1

3.74e-0412838319058789
Pubmed

Genetical genomic determinants of alcohol consumption in rats and humans.

OPRK1 OPRL1 OPRM1

3.91e-0413038319874574
Pubmed

Molecular and anatomical characterization of parabrachial neurons and their axonal projections.

OXTR OPRM1

4.63e-042938236317965
Pubmed

Joint influence of small-effect genetic variants on human longevity.

ABCC4 SSTR3

6.38e-043438220834067
Pubmed

HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.

CD46 TNFRSF8

8.83e-044038225275127
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

GJC2 OXTR PARP8 OPRL1 OPRM1

9.25e-0469738528298427
Pubmed

Association study of 182 candidate genes in anorexia nervosa.

GALR1 OPRK1 OPRM1

1.04e-0318238320468064
InteractionGPRASP1 interactions

OXTR OPRK1 OPRL1 OPRM1

6.78e-0667374int:GPRASP1
InteractionSLC41A1 interactions

GPR101 TMEM237 OPRM1

5.37e-0540373int:SLC41A1
InteractionLAT interactions

ZDHHC20 GPR101 TMEM237 OPRM1

6.15e-05117374int:LAT
InteractionOPRD1 interactions

TMEM237 OPRK1 OPRM1

1.12e-0451373int:OPRD1
GeneFamilyOpioid receptors

OPRK1 OPRL1 OPRM1

2.01e-084323245
GeneFamilyATP binding cassette subfamily C

ABCC11 ABCC4

2.34e-0413322807
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC20 ZDHHC16

8.17e-042432276
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNMB4 OXTR OPRK1 OPRM1

6.83e-0614438471107275767a0728541a3695715c44874b3e5efc
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRLHR KIAA1549L USH2A OPRK1

1.20e-05166384afba41e15478053f11815acf568d29187de75492
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIAA1549 CD46 SLC5A10 MPZL1

1.47e-05175384aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DAGLB GJC2 OXTR TNFRSF8

1.75e-0518338489727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DAGLB GJC2 OXTR TNFRSF8

1.75e-05183384113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

TMEM184C GJC2 EDNRB MPZL1

1.99e-051893843922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NPBWR1 SLC5A10 GPR101

2.03e-0562383a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NPBWR1 SLC5A10 GPR101

2.03e-0562383ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 KCNMB4 EDNRB OPRL1

2.08e-05191384ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 KCNMB4 EDNRB OPRL1

2.08e-05191384478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR1 SSTR3 P2RY1 USH2A

2.12e-051923845b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

TMEM184C GJC2 EDNRB MPZL1

2.21e-05194384927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMB4 GALR1 KIAA1549L EDNRB

2.34e-051973845c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMB4 GALR1 KIAA1549L EDNRB

2.34e-05197384c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ComputationalGenes in the cancer module 367.

OXTR P2RY1 EDNRB

1.95e-0529203MODULE_367
ComputationalGenes in the cancer module 134.

OXTR EDNRB OPRK1

2.17e-0530203MODULE_134
ComputationalGenes in the cancer module 288.

OXTR EDNRB OPRK1

4.11e-0537203MODULE_288
ComputationalGenes in the cancer module 287.

OXTR USH2A EDNRB

1.02e-0450203MODULE_287
ComputationalGenes in the cancer module 27.

OXTR TNFRSF8 EDNRB OPRK1 OPRM1

3.93e-04355205MODULE_27
ComputationalGenes in the cancer module 146.

OXTR EDNRB OPRK1

8.41e-04102203MODULE_146
ComputationalGenes in the cancer module 330.

CLCN1 OXTR

1.21e-0328202MODULE_330
ComputationalMembranal receptors.

OXTR HAS3 EDNRB OPRK1 MPZL1

2.14e-03517205MODULE_64
Drug2-mercaptoacetate

GALR1 OPRK1 OPRL1 OPRM1

2.30e-107384ctd:C017487
DrugNeuropeptide Ff

PRLHR GALR1 GPR101 OPRK1 OPRL1 OPRM1

1.59e-0969386CID000123797
Drug443C81

OXTR OPRK1 OPRL1 OPRM1

6.52e-0914384CID000130949
DrugAC1L1KRB

DAGLB OXTR P2RY1 EDNRB OPRL1

2.94e-0854385CID000005621
DrugFdUMP

ABCC11 ABCC4 TNFRSF8 OPRK1 OPRL1

6.45e-0863385CID000001816
DrugEtorphine

OPRK1 OPRL1 OPRM1

8.55e-086383DB01497
DrugAC1L2OET

OPRK1 OPRL1 OPRM1

8.55e-086383CID000125331
DrugNSC612111

OPRK1 OPRL1 OPRM1

8.55e-086383CID000163346
DrugRX8008M

OPRK1 OPRL1 OPRM1

8.55e-086383CID000162443
Drugcyclamate

CLCN1 OPRK1 OPRL1 OPRM1

1.31e-0728384CID000007533
DrugTyr-ala-phe-gly

OPRK1 OPRL1 OPRM1

1.49e-077383CID005487532
DrugMET-CAMO

OPRK1 OPRL1 OPRM1

1.49e-077383CID006450159
Drugphenylmorphan

OPRK1 OPRL1 OPRM1

1.49e-077383CID000146306
DrugAC1L9PCU

OPRK1 OPRL1 OPRM1

1.49e-077383CID000451042
DrugN-cyclopropylmethylnorazidomorphine

OPRK1 OPRL1 OPRM1

1.49e-077383CID005489191
Drugbeta-naltrexamine

OPRK1 OPRL1 OPRM1

1.49e-077383CID005486948
DrugNDTMB

OPRK1 OPRL1 OPRM1

1.49e-077383CID000134748
DrugKelatorphan

GALR1 OPRK1 OPRL1 OPRM1

1.75e-0730384CID000123982
DrugAC1N8H7N

ABCC4 HAS3 OPRK1 OPRL1 OPRM1

1.90e-0778385CID004318740
Drugdl-Bremazocine

NPBWR1 OPRK1 OPRL1 OPRM1

2.01e-0731384CID000001223
DrugICI 204448

OPRK1 OPRL1 OPRM1

2.39e-078383CID000003683
Drugmetazocine

OPRK1 OPRL1 OPRM1

2.39e-078383CID000062518
DrugAC1L1B1Q

OPRK1 OPRL1 OPRM1

2.39e-078383CID000001246
DrugDIPPA

OPRK1 OPRL1 OPRM1

2.39e-078383CID000127914
Drug14-methoxymetopon

OPRK1 OPRL1 OPRM1

2.39e-078383CID005486940
DrugKT-89

OPRK1 OPRL1 OPRM1

2.39e-078383CID005748450
Drugbinaltorphimine

OPRK1 OPRL1 OPRM1

2.39e-078383CID005484197
DrugN-methyl nalorphine

OPRK1 OPRL1 OPRM1

2.39e-078383CID005748235
DrugAC1LBBLW

OPRK1 OPRL1 OPRM1

2.39e-078383CID000579851
DrugOxymorphone hydrazone

OPRK1 OPRL1 OPRM1

2.39e-078383CID009577748
DrugTyr-D-Ala-Gly-Phe-Leu-chloromethyl ketone

OPRK1 OPRL1 OPRM1

2.39e-078383CID005492572
Drugserotonin

CD46 GALR1 CLCN1 GPR101 P2RY1 POLR2C OPRK1 OPRL1 OPRM1

2.44e-07554389CID000005202
DrugDam K

OPRK1 OPRL1 OPRM1

3.58e-079383CID005487344
DrugAC1LD4H9

OPRK1 OPRL1 OPRM1

3.58e-079383CID000611919
DrugM 285

OPRK1 OPRL1 OPRM1

3.58e-079383CID000020435
Drugmeptazinol

OPRK1 OPRL1 OPRM1

3.58e-079383CID000041049
DrugMRZ 2549

OPRK1 OPRL1 OPRM1

3.58e-079383CID000134837
DrugSyndyphalin

OPRK1 OPRL1 OPRM1

3.58e-079383CID000174117
Drugphenylquinone

EDNRB OPRK1 OPRL1 OPRM1

3.74e-0736384CID000009688
Drugprofadol

OPRK1 OPRL1 OPRM1

5.11e-0710383CID000009882
DrugAC1LCF1O

OPRK1 OPRL1 OPRM1

5.11e-0710383CID000627285
Drugnormetazocine

OPRK1 OPRL1 OPRM1

5.11e-0710383CID000001208
DrugNaloxone-6-hydrazone

OPRK1 OPRL1 OPRM1

5.11e-0710383CID009576788
Drugbeta-FNA

OXTR OPRK1 OPRL1 OPRM1

5.20e-0739384CID005137129
DrugMorphiceptin

SSTR3 OPRK1 OPRL1 OPRM1

5.77e-0740384CID000119303
DrugAC1L1I54

SSTR3 OPRK1 OPRL1 OPRM1

6.39e-0741384CID000004426
DrugPD117302

OPRK1 OPRL1 OPRM1

7.01e-0711383CID000122115
DrugTrimu-5

OPRK1 OPRL1 OPRM1

7.01e-0711383CID005487273
DrugWy-16,225

OPRK1 OPRL1 OPRM1

7.01e-0711383CID000040841
DrugO-desmethyltramadol

OPRK1 OPRL1 OPRM1

7.01e-0711383CID000130829
DrugAC1LCENG

OPRK1 OPRL1 OPRM1

7.01e-0711383CID000626667
DrugAC1L1I4J

OPRK1 OPRL1 OPRM1

7.01e-0711383CID000004419
Drugmethyl (E)-4-[[(4R,4aR,7R,7aR,12bS)-3-(cyclopropylmethyl)-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]amino]-4-oxobut-2-enoate

NPBWR1 OXTR OPRK1 OPRL1

7.77e-0743384CID016072169
Drugcyclazocine

OPRK1 OPRL1 OPRM1

9.34e-0712383CID000019143
Drugdihydroetorphine

OPRK1 OPRL1 OPRM1

9.34e-0712383CID000107765
DrugAC1L1KS5

DAGLB NPBWR1 OXTR P2RY1 EDNRB OPRL1 SLC5A2

1.17e-06334387CID000005631
Drug3-(4-chlorophenyl)-N-[3-(cyclopropylmethyl)-9-hydroxy-7-keto-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]acrylamide

OPRK1 OPRL1 OPRM1

1.21e-0613383CID005149020
Drugetonitazene

OPRK1 OPRL1 OPRM1

1.21e-0613383CID000013493
Drugcyprodime hydrobromide

OPRK1 OPRL1 OPRM1

1.21e-0613383CID005748293
Drugmethadol

OPRK1 OPRL1 OPRM1

1.21e-0613383CID000028397
Drugquadazocine

OPRK1 OPRL1 OPRM1

1.54e-0614383CID000115077
DrugTDAM

OPRK1 OPRL1 OPRM1

1.54e-0614383CID000124899
DrugTRK-820

OPRK1 OPRL1 OPRM1

1.54e-0614383CID006445230
Drugnaltrindole-5'-isothiocyanate

OPRK1 OPRL1 OPRM1

1.54e-0614383CID005487327
DrugTdagp

OPRK1 OPRL1 OPRM1

1.54e-0614383CID005491936
Drug6-.beta.-Naltrexol

OPRK1 OPRL1 OPRM1

1.54e-0614383CID000631219
DrugI06-1317

OPRK1 OPRL1 OPRM1

1.54e-0614383CID003081923
Drugnalmefene HCl

EDNRB OPRK1 OPRL1 OPRM1

1.69e-0652384CID000004422
Drug3-methylfentanyl

OPRK1 OPRL1 OPRM1

1.92e-0615383CID000061996
DrugKetazocina

OPRK1 OPRL1 OPRM1

1.92e-0615383CID000071426
DrugFedotozina

OPRK1 OPRL1 OPRM1

1.92e-0615383CID000060764
DrugTyr-w-mif-1

OPRK1 OPRL1 OPRM1

1.92e-0615383CID000132632
DrugTIPPpsi

OPRK1 OPRL1 OPRM1

1.92e-0615383CID005311481
DrugE-2078

OPRK1 OPRL1 OPRM1

2.37e-0616383CID000122220
DrugDstbulet

OPRK1 OPRL1 OPRM1

2.37e-0616383CID000130662
DrugDynorphin (1-8)

OPRK1 OPRL1 OPRM1

2.37e-0616383CID000108135
DrugIci 154129

OPRK1 OPRL1 OPRM1

2.37e-0616383CID003035055
Drugclonidine

CD46 GALR1 P2RY1 OPRK1 OPRL1 OPRM1

2.68e-06240386CID000002803
Drug3-dadh-ol

OPRK1 OPRM1

2.71e-062382CID000128663
DrugDezocine

OPRK1 OPRM1

2.71e-062382DB01209
DrugGUM1 compound

OPRK1 OPRM1

2.71e-062382ctd:C000611307
DrugP 7521

OPRK1 OPRM1

2.71e-062382CID000146384
DrugN-propargyl

OPRK1 OPRM1

2.71e-062382ctd:C440369
DrugN-(3-iodoprop-(2)-enyl)

OPRK1 OPRM1

2.71e-062382ctd:C440388
Drugmethyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo(2,3-a)quinolizin-2-yl)-3-methoxyacrylate

OPRK1 OPRM1

2.71e-062382ctd:C533093
DrugCyclazocine

OPRK1 OPRM1

2.71e-062382ctd:D003496
Drugpaynantheine

OPRK1 OPRM1

2.71e-062382ctd:C580857
Drugdihydroheroin

OPRK1 OPRM1

2.71e-062382CID005359460
Drugetorphine

SSTR3 OPRK1 OPRL1 OPRM1

2.81e-0659384CID000026721
DrugTyr-mif-1

OPRK1 OPRL1 OPRM1

2.87e-0617383CID000115085
Drugfentanyl isothiocyanate

OPRK1 OPRL1 OPRM1

2.87e-0617383CID000084008
DrugDalce

OPRK1 OPRL1 OPRM1

2.87e-0617383CID005486712
DrugNSC404353

OPRK1 OPRL1 OPRM1

3.44e-0618383CID000273032
DrugMR 2034

OPRK1 OPRL1 OPRM1

3.44e-0618383CID000123980
DrugBUBUC

OPRK1 OPRL1 OPRM1

3.44e-0618383CID006324600
Drugohmefentanyl

OPRK1 OPRL1 OPRM1

3.44e-0618383CID000062279
DrugBuprenorphine

OPRK1 OPRL1 OPRM1

3.44e-0618383ctd:D002047
DrugAC1L1DSH

OPRK1 OPRL1 OPRM1

4.08e-0619383CID000002487
Drugtrimebutine

OPRK1 OPRL1 OPRM1

4.08e-0619383CID000005573
DrugDanmme

OPRK1 OPRL1 OPRM1

4.08e-0619383CID005486529
DiseaseParkinson's disease (implicated_via_orthology)

NPBWR1 PRLHR SSTR3 OPRK1 OPRL1 OPRM1

3.52e-08157366DOID:14330 (implicated_via_orthology)
DiseaseMorphine Dependence

OPRL1 OPRM1

3.03e-057362C0026552
DiseaseMorphine Abuse

OPRL1 OPRM1

3.03e-057362C0600272
DiseaseCardiac Arrhythmia

OPRK1 OPRL1

4.27e-0425362C0003811
DiseaseCocaine Dependence

GALR1 OPRK1 OPRM1

6.52e-04139363C0600427
DiseaseCognition Disorders

ABCC4 OXTR

9.90e-0438362C0009241
Diseasechildhood trauma measurement, smoking behaviour measurement

NPBWR1 OPRK1

1.39e-0345362EFO_0005671, EFO_0007979
DiseaseHepatic fibrosis

OXTR KIAA1549L

1.64e-0349362HP_0001395
DiseaseWithdrawal Symptoms

OPRK1 OPRL1

2.29e-0358362C0087169
DiseaseDrug Withdrawal Symptoms

OPRK1 OPRL1

2.29e-0358362C0086189
DiseaseSubstance Withdrawal Syndrome

OPRK1 OPRL1

2.29e-0358362C0038587
Diseaseserum IgE measurement

NPBWR1 OPRK1

2.78e-0364362EFO_0004579
Diseasemyocardial infarction (implicated_via_orthology)

EDNRB OPRK1

2.96e-0366362DOID:5844 (implicated_via_orthology)
Diseasepentachlorophenol measurement

USH2A OPRK1

3.60e-0373362EFO_0022071
Diseaseparathion measurement

USH2A OPRK1

3.60e-0373362EFO_0022070

Protein segments in the cluster

PeptideGeneStartEntry
VKLVVFVSFWQAVVI

TMEM184C

251

Q9NVA4
EIVLIWVVSVVLAVP

EDNRB

221

P24530
WSFIVPVTIILISNV

ADGRG7

626

Q96K78
IFVLIPVSWTANIII

CLDN17

131

P56750
SNNLWVIVGVVIPVL

KIAA1549

1296

Q9HCM3
ISVLVWLIVVVAISP

P2RY1

171

P47900
VVVAVFIVCWTPIHI

OPRM1

286

P35372
IAVAWEVIRTEPIIV

PARP8

196

Q8N3A8
SLDVWVIAVIVIAIV

CD46

341

P15529
VPWEIFLITLVSVVA

MUC21

476

Q5SSG8
HVRFWVFQIVVISTP

GJC2

76

Q5T442
FIIPTVATAVWVLIH

ABCC11

391

Q96J66
WIIAAVLAPIAVVTV

KIAA1549L

1181

Q6ZVL6
DVETQVPQWVITIII

GPR101

426

Q96P66
ITWITLAVYIVPVIV

OXTR

201

P30559
PVFPVWVVVGIVTAV

MPZL1

161

O95297
VGVVSVAVAVIPWIA

ABCC4

851

O15439
AQTVLVVVVVFGISW

GALR1

246

P47211
WIIIAATVVSIIIVF

DAGLB

141

Q8NCG7
VVSWGVPLVITVAAV

GPR157

126

Q5UAW9
WPLVTFVVGVLIVVL

KCNMB4

176

Q86W47
VNFIGLIPVSIWVAV

HAS3

476

O00219
AVWGIVTLVVLPFAV

NPBWR1

161

P48145
VLVVVAVFVVCWTPI

OPRK1

276

P41145
LVVVAVFVGCWTPVQ

OPRL1

266

P41146
PEVVIINSTAVRVIW

USH2A

3026

O75445
VVIVVVFAVCWLPLH

PRLHR

281

P49683
AVWVASAVVVLPVVV

SSTR3

166

P32745
RVFIAEVPIIAIDWV

POLR2C

36

P19387
SAVWIHPRVNVVIII

CLCN1

446

P35523
EEQILQPWIVVNLVV

TMEM237

351

Q96Q45
QRVVGWVPVLFITFV

ZDHHC20

11

Q5W0Z9
EVWVVVYTIPAVLTL

TMEM220

31

Q6QAJ8
VFIVVVSVAWLPVVQ

SLC5A2

431

P31639
VIVALIGVSVAWIPV

SLC5A10

416

A0PJK1
PVLFWVILVLVVVVG

TNFRSF8

386

P28908
TVVLFVPQQEAWVVE

STOML2

36

Q9UJZ1
IRWFGVVFVVLVIVL

ZDHHC16

76

Q969W1