Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

MYT1L ZNF823 ZNF355P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF772 THAP1 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 GTF2IRD2B ZNF716 ZNF676 THRB ZNF425 NFKB2 ZNF347 GTF2IRD2 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

2.02e-21141210642GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

MYT1L ZNF823 ZNF355P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF772 THAP1 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 THRB ZNF425 NFKB2 ZNF347 ZNF624 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF44

2.79e-17145910638GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

MYT1L ZNF355P ZNF586 ZNF493 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF772 THAP1 ZBTB14 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF716 ZNF676 THRB NFKB2 ZNF347 ZNF624 ZNF721 ZNF860 ZNF107

2.13e-10124410627GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

MYT1L ZNF355P ZNF586 ZNF493 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF772 THAP1 ZBTB14 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF716 ZNF676 THRB NFKB2 ZNF347 ZNF624 ZNF721 ZNF860 ZNF107

3.43e-10127110627GO:0000987
GeneOntologyMolecularFunctionextracellularly glycine-gated ion channel activity

GLRA3 GLRA1 GLRA2

2.87e-0661063GO:0016933
GeneOntologyMolecularFunctionextracellularly glycine-gated chloride channel activity

GLRA3 GLRA1 GLRA2

2.87e-0661063GO:0016934
GeneOntologyMolecularFunctioninhibitory extracellular ligand-gated monoatomic ion channel activity

GLRA3 GLRA1 GLRA2

7.99e-0681063GO:0005237
GeneOntologyMolecularFunctionglycine-gated chloride ion channel activity

GLRA3 GLRA2

2.79e-0521062GO:0022852
GeneOntologyMolecularFunctionglycine binding

GLRA3 GLRA1 GLRA2

5.07e-05141063GO:0016594
GeneOntologyMolecularFunctionamino acid binding

MAT1A GLRA3 GLRA1 GLRA2

6.16e-04731064GO:0016597
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

MYT1L ZNF493 WT1 ZFY NFKB2 ZNF624 PLAGL2 ZNF721 ZNF107 ZNF292

7.94e-0456010610GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

MYT1L ZNF493 WT1 ZFY NFKB2 ZNF624 PLAGL2 ZNF721 ZNF107 ZNF292

8.61e-0456610610GO:0001216
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

GLRA3 GLRA1 GLRA2

1.54e-03431063GO:0005231
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

MYT1L ZNF493 THAP1 ZBTB14 ZBTB37 ZNF721 ZNF107

1.60e-033201067GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

MYT1L ZNF493 THAP1 ZBTB14 ZBTB37 ZNF721 ZNF107

1.78e-033261067GO:0001217
GeneOntologyCellularComponentglycinergic synapse

GLRA3 GLRA1 GLRA2

1.32e-04201053GO:0098690
Domainzf-C2H2

ZNF823 ZNF137P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

8.80e-2869310538PF00096
DomainZnF_C2H2

ZNF823 ZNF137P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 GTF2IRD2B ZNF716 ZNF676 ZNF425 ZNF347 GTF2IRD2 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

1.21e-2780810540SM00355
DomainZnf_C2H2-like

ZNF823 ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 GTF2IRD2B ZNF716 ZNF676 ZNF425 ZNF347 GTF2IRD2 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

9.78e-2779610539IPR015880
DomainZINC_FINGER_C2H2_2

ZNF823 ZNF137P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

5.12e-2677510538PS50157
DomainZINC_FINGER_C2H2_1

ZNF823 ZNF137P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

5.62e-2677710538PS00028
Domain-

ZNF823 ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

9.79e-26679105363.30.160.60
DomainZnf_C2H2

ZNF823 ZNF137P ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

2.01e-2580510538IPR007087
DomainZnf_C2H2/integrase_DNA-bd

ZNF823 ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

2.08e-2569410536IPR013087
DomainKRAB

ZNF823 ZNF586 ZNF560 ZNF674 ZNF254 ZNF429 ZFP28 ZNF571 ZNF214 ZNF772 ZNF441 ZNF419 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 ZNF860 ZNF700 ZNF791 ZNF669 ZNF44

2.06e-1935810524PS50805
DomainKRAB

ZNF823 ZNF586 ZNF560 ZNF674 ZNF254 ZNF429 ZFP28 ZNF571 ZNF214 ZNF772 ZNF441 ZNF419 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 ZNF860 ZNF700 ZNF791 ZNF669 ZNF44

4.16e-1936910524SM00349
DomainKRAB

ZNF823 ZNF586 ZNF560 ZNF674 ZNF254 ZNF429 ZFP28 ZNF571 ZNF214 ZNF772 ZNF441 ZNF419 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 ZNF860 ZNF700 ZNF791 ZNF669 ZNF44

4.43e-1937010524IPR001909
DomainKRAB

ZNF823 ZNF586 ZNF560 ZNF674 ZNF254 ZNF429 ZFP28 ZNF571 ZNF214 ZNF772 ZNF441 ZNF419 ZNF34 ZNF19 ZNF716 ZNF425 ZNF347 ZNF624 ZNF860 ZNF700 ZNF791 ZNF669 ZNF44

3.29e-1835810523PF01352
Domainzf-C2H2_6

ZNF823 ZNF586 ZNF493 ZNF560 ZNF429 ZFP28 ZNF571 ZNF419 ZNF676 ZNF425 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF44

1.12e-1431410519PF13912
DomainGlycine_rcpt_A

GLRA3 GLRA1 GLRA2

6.88e-0741053IPR008127
DomainKinesin_light_repeat

KLC2 KLC1

9.36e-0531052IPR015792
DomainKINESIN_LIGHT

KLC2 KLC1

9.36e-0531052PS01160
Domain-

GTF2IRD2B GTF2IRD2

1.86e-04410523.90.1460.10
DomainFAM47

FAM47C FAM47B

1.86e-0441052PF14642
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.86e-0441052PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.86e-0441052PF02946
DomainFAM47

FAM47C FAM47B

1.86e-0441052IPR032743
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.86e-0441052IPR004212
DomainKinesin_light

KLC2 KLC1

1.86e-0441052IPR002151
DomainGABAA/Glycine_rcpt

GLRA3 GLRA1 GLRA2

2.82e-04231053IPR006028
DomainRab5-bind

KLC2 KLC1

4.63e-0461052PF09311
DomainRabaptin_Rab5-bd_dom

KLC2 KLC1

4.63e-0461052IPR015390
DomainTPR_10

KLC2 KLC1

4.63e-0461052PF13374
DomainNeurotransmitter_ion_chnl_CS

GLRA3 GLRA1 GLRA2

2.06e-03451053IPR018000
DomainNeur_chan_memb

GLRA3 GLRA1 GLRA2

2.20e-03461053PF02932
DomainNeur_chan_LBD

GLRA3 GLRA1 GLRA2

2.34e-03471053PF02931
DomainNEUROTR_ION_CHANNEL

GLRA3 GLRA1 GLRA2

2.34e-03471053PS00236
DomainNeurotrans-gated_channel_TM

GLRA3 GLRA1 GLRA2

2.34e-03471053IPR006029
Domain-

GLRA3 GLRA1 GLRA2

2.34e-034710532.70.170.10
DomainNeur_channel

GLRA3 GLRA1 GLRA2

2.34e-03471053IPR006201
DomainNeur_chan_lig-bd

GLRA3 GLRA1 GLRA2

2.34e-03471053IPR006202
DomainKelch_2

LZTR1 ATRNL1

2.35e-03131052IPR011498
DomainKelch_2

LZTR1 ATRNL1

2.35e-03131052PF07646
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF586 ZNF493 ZNF560 ZNF254 ZNF429 ZFP28 ZNF571 ZNF214 ZNF772 ITGA4 RFC3 ZNF441 ZNF419 HIVEP3 ZNF34 ZNF19 ZNF716 ZNF676 THRB ZNF425 ZNF347 ZNF624 ZNF721 ZNF860 ZNF700 ZNF791 ZNF669

1.70e-0913877727M734
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

ZNF823 ZNF355P ZNF493 ZNF254 ZNF429 ZFP28 RFC3 ZNF419 THRB ZNF347 ZNF624 ZNF721 ZNF107 ZNF44

6.15e-057687714MM14851
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF355P ZNF493 ZNF254 ZNF429 ZNF716 ZNF721 ZNF107

3.37e-1229108714563677
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF355P ZNF493 ZNF254 ZNF429 ZNF721 ZNF107

3.81e-1215108615885501
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF355P ZNF493 ZNF429 ZNF347 ZNF624 ZNF721 ZNF107

1.76e-104910879630514
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF493 ZNF441 ZNF419 ZNF34 ZNF624 ZNF721 ZNF107 ZNF791 ZNF669 ZNF44

2.83e-101811081037372979
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MYT1L LZTR1 ZNF254 WT1 ZNF429 ZFP28 ZNF322 ZFP36 ZNF419 HIVEP3 ZBTB37 ZNF716 NFKB2 ZNF347 PLAGL2 ZNF721 ZNF292

5.43e-108081081720412781
Pubmed

Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice.

GLRA3 GLRA1 GLRA2

2.91e-083108317920294
Pubmed

Glycinergic input of widefield, displaced amacrine cells of the mouse retina.

GLRA3 GLRA1 GLRA2

1.16e-074108319528249
Pubmed

Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.

GLRA3 GLRA1 GLRA2

1.16e-07410839051263
Pubmed

Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.

GLRA3 GLRA1 GLRA2

1.16e-074108321486797
Pubmed

Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.

GLRA3 GLRA1 GLRA2

2.90e-075108321850450
Pubmed

Calsyntenin-1 docks vesicular cargo to kinesin-1.

KLC2 CLSTN1 KLC1

2.90e-075108316760430
Pubmed

Native glycine receptor subtypes and their physiological roles.

GLRA3 GLRA1 GLRA2

2.90e-075108318721822
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF355P ZNF254 ZNF429 ZNF624

4.10e-072010847479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF355P ZNF254 ZNF429 ZNF624

4.10e-072010842542606
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF355P ZNF254 ZNF429

5.78e-076108330846446
Pubmed

A census of human transcription factors: function, expression and evolution.

MYT1L NSD2 ZNF254 WT1 ZNF322 THAP1 ZBTB14 ZFY HIVEP3 ZNF19 THRB NFKB2 PLAGL2 ZNF44

8.91e-079081081419274049
Pubmed

The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.

KLC2 CLSTN1 KLC1

1.01e-067108317332754
Pubmed

Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.

GLRA3 GLRA1 GLRA2

1.01e-067108322988142
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF493 ZNF721 ZNF107

3.44e-0610108318588511
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF493 ZNF721 ZNF107

4.72e-0611108315469996
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF493 ZNF721 ZNF107

8.14e-0613108319850934
Pubmed

Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors.

GLRA1 GLRA2

9.55e-062108216144831
Pubmed

Characterization of the glycinergic input to bipolar cells of the mouse retina.

GLRA3 GLRA1

9.55e-062108216420443
Pubmed

Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice.

GLRA1 GLRA2

9.55e-062108234378188
Pubmed

Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.

KLC2 KLC1

9.55e-062108229036226
Pubmed

Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.

GLRA3 GLRA1

9.55e-062108221486794
Pubmed

Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site.

GLRA3 GLRA1

9.55e-062108223834509
Pubmed

The Wilms tumor suppressor Wt1 promotes cell adhesion through transcriptional activation of the alpha4integrin gene.

WT1 ITGA4

9.55e-062108216920711
Pubmed

Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.

GLRA3 GLRA2

9.55e-062108227382060
Pubmed

Structure of the human alpha 2 subunit gene of the glycine receptor--use of vectorette and Alu-exon PCR.

GLRA1 GLRA2

9.55e-06210828973915
Pubmed

Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

GLRA1 GLRA2

9.55e-06210822155780
Pubmed

Selective glycine receptor α2 subunit control of crossover inhibition between the on and off retinal pathways.

GLRA3 GLRA2

9.55e-062108222399754
Pubmed

Phylogenetic relationships and chromosomal location of five distinct glycine receptor subunit genes in the teleost Danio rerio.

GLRA1 GLRA2

9.55e-062108211685575
Pubmed

Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism.

GLRA1 GLRA2

9.55e-062108215147510
Pubmed

Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms.

KLC2 KLC1

9.55e-062108222470497
Pubmed

Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain.

GLRA3 GLRA2

9.55e-062108228784756
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

9.55e-062108215388857
Pubmed

Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting.

GLRA3 GLRA1

9.55e-062108219959465
Pubmed

Constitutive cleavage of the single-pass transmembrane protein alcadeinα prevents aberrant peripheral retention of Kinesin-1.

CLSTN1 KLC1

9.55e-062108222905201
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RTEL1 ZFP28 CLSTN1 HIVEP3 PLEKHG3 ATRNL1 ZNF347 TAOK1 PUS7

2.43e-05493108915368895
Pubmed

Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy.

DSP WT1

2.86e-053108233726497
Pubmed

Structural basis for kinesin-1:cargo recognition.

KLC2 CLSTN1

2.86e-053108223519214
Pubmed

Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.

HIVEP3 ZNF292

2.86e-053108225849321
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.86e-053108215100712
Pubmed

Diversity of glycine receptors in the mouse retina: localization of the alpha4 subunit.

GLRA3 GLRA1

2.86e-053108217154252
Pubmed

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.

CLSTN1 KLC1

2.86e-053108221385839
Pubmed

Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.

ZNF355P ZNF254 ZNF429 ZNF624

4.00e-056110848662221
Pubmed

Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variant.

GLRA1 GLRA2

5.71e-05410827507926
Pubmed

Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains.

KLC2 KLC1

5.71e-054108219861499
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2IRD2

5.71e-054108217823943
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2IRD2

5.71e-054108223229069
Pubmed

Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.

KLC2 KLC1

5.71e-054108211106729
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2IRD2

5.71e-054108222899722
Pubmed

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.

GLRA3 GLRA1

5.71e-054108228883437
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2IRD2

5.71e-054108221328569
Pubmed

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

GLRA3 GLRA1 GLRA2

8.07e-0527108319723784
Pubmed

The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).

ZBTB14 ZFY

9.50e-05510829244432
Pubmed

Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility.

KLC2 KLC1

9.50e-055108221750526
Pubmed

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.

KLC2 KLC1

9.50e-055108219164528
Pubmed

Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization.

OTUB1 NFKB2

9.50e-055108231086255
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF254 ZNF429

9.50e-055108224190968
Pubmed

The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse.

SCRN3 WT1

9.50e-055108233442887
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF254 ZNF429

9.50e-055108220042539
Pubmed

Defective kinesin heavy chain behavior in mouse kinesin light chain mutants.

KLC2 KLC1

9.50e-055108210491391
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

VPS13C ZFP28 ZNF624 TAOK1 LRP2BP

1.19e-04153108510718198
Pubmed

Unique functions of Gata4 in mouse liver induction and heart development.

WT1 ITGA4

1.42e-046108226687508
Pubmed

Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents.

GLRA1 GLRA2

1.42e-04610827891186
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF254 ZNF429

1.99e-047108222801370
Pubmed

Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.

KLC2 KLC1

1.99e-047108221335237
Pubmed

Specific and ubiquitous expression of different Zn finger protein genes in the mouse.

ZFP28 ZNF624

1.99e-04710823143103
Pubmed

RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.

KLC2 KLC1

2.64e-048108234432492
Pubmed

Origin of congenital coronary arterio-ventricular fistulae from anomalous epicardial and myocardial development.

WT1 ITGA4

2.64e-048108236653444
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYT1L RTEL1 NSD2 USP24

3.18e-04104108410470851
Pubmed

Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.

KLC2 KLC1

3.39e-04910829624122
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

USP24 USP54

3.39e-049108237149635
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF254 ZNF429

3.39e-049108210360839
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

MYT1L LZTR1 OTUB1 WT1 ZFP28 ZBTB14 ZFY PLAGL2 ZNF292

3.76e-04709108922988430
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF137P LZTR1 WT1 ZFP28 ZFP36 ZFY THRB NFKB2 PLAGL2 ZNF292

4.13e-048771081020211142
Pubmed

A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.

KLC2 KLC1

4.23e-0410108221915095
Pubmed

Generation and characterization of a Myh6-driven Cre knockin mouse line.

DSP WT1

4.23e-0410108234542814
Pubmed

Dynein and kinesin regulate stress-granule and P-body dynamics.

KLC2 KLC1

4.23e-0410108219825938
Pubmed

WT1 regulates expression of DNA repair gene Neil3 during nephrogenesis.

WT1 NEIL3

4.23e-0410108236546838
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

MAT1A RPS5 ZNF571 ZNF716 THRB ZNF107 KLB

5.33e-04451108736168627
Pubmed

Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome.

GLRA3 GLRA2

6.18e-041210821679744
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

MYT1L HIVEP3

6.18e-0412108227824329
Pubmed

Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling.

MRC1 WT1

6.18e-0412108233130914
Pubmed

Zinc finger protein genes in the mouse genome.

WT1 ZFY

6.18e-041210821797234
Pubmed

The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.

KLC2 KLC1

6.18e-0412108216018997
Pubmed

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.

KLC2 KLC1

6.18e-0412108216301330
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

SCRN3 MYO9A NSD2 KLC2 ZBTB14 GTF2IRD2B TM2D2 TMPRSS3 PUS7 KLC1

6.24e-049251081028986522
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L DSP ZNF214 PREPL ZFP36 ZNF34 PTPN13 ATRNL1 ZNF624 TAOK1 USP54 ZNF292

6.55e-0412851081235914814
Pubmed

PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.

WT1 ITGA4

7.29e-0413108216510507
Pubmed

Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart.

DSP WT1

7.29e-0413108234737300
Pubmed

Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.

OTUB1 USP24

7.29e-0413108235913115
Pubmed

Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.

ZFY GLRA2

8.48e-041410828432533
Pubmed

CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane.

WT1 ITGA4

9.77e-0415108228465335
Pubmed

The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.

WT1 ITGA4

1.11e-0316108221350012
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF137P ZNF19

1.26e-031710827557990
Pubmed

Loss of transforming growth factor-beta 2 leads to impairment of central synapse function.

GLRA1 GLRA2

1.42e-0318108218854036
Pubmed

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.

VPS13C PUS7

1.42e-0318108227984743
Cytoband19p13.2

ZNF823 ZNF560 ZNF414 ZNF491 ZNF441 ZNF700 ZNF791 ZNF44

8.36e-08229109819p13.2
CytobandXp21.1

FAM47C FAM47B FAM47DP

7.38e-05341093Xp21.1
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF493 ZNF254 ZNF429 ZNF676

2.13e-041221094chr19p12
CytobandEnsembl 112 genes in cytogenetic band chr3p23

GADL1 ZNF860

2.48e-04101092chr3p23
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF137P ZNF586 RPS5 ZFP28 ZNF571 ZNF772 ZFP36 ZNF419 ZNF347 VSTM1

5.61e-04119210910chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ZNF823 ZNF560 ZNF414 ZNF491 ZNF441 ZNF700 ZNF791 ZNF44

6.49e-047971098chr19p13
CytobandEnsembl 112 genes in cytogenetic band chrXp21

FAM47C FAM47B FAM47DP

1.08e-03841093chrXp21
Cytoband19q13.43

ZNF586 ZNF772 ZNF419

1.19e-0387109319q13.43
Cytoband19p12

ZNF493 ZNF254 ZNF676

1.32e-0390109319p12
Cytoband14q23.3

FNTB PLEKHG3

1.75e-0326109214q23.3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF823 ZNF586 ZNF493 ZNF560 ZNF674 ZNF254 WT1 ZNF429 ZFP28 ZNF571 ZNF322 ZNF214 ZNF772 ZNF414 ZNF491 ZBTB14 ZNF441 ZFY ZNF419 HIVEP3 ZBTB37 ZNF34 ZNF19 ZNF716 ZNF676 ZNF425 ZNF347 ZNF624 PLAGL2 ZNF721 ZNF860 ZNF700 ZNF107 ZNF791 ZNF669 ZNF292 ZNF44

4.52e-29718873728
GeneFamilyGlycine receptors

GLRA3 GLRA1 GLRA2

1.07e-065873868
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF586 ZNF254 APOBEC3H PLEKHG3 ZNF624 USP54

2.86e-061611096f470b662566131dfe69a2fd01186ac8491196396
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RTEL1 ZNF429 PREPL ZNF107 NOL8 LRP2BP

3.41e-061661096f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCNJL MYO9A CPM PTPN13 THRB EDEM1

8.33e-061941096df835578d86a49ae5af5632152fbab9548c0a448
ToppCellcellseq2-Epithelial-Epithelial_Alveolar|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCNJL MYO9A CPM PTPN13 THRB EDEM1

8.33e-0619410960715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCNJL MYO9A CPM PTPN13 THRB EDEM1

8.33e-061941096a4f7cd507eba40985d82635bbae28c7f5703f883
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYT1L OTUB1 KLC2 CLSTN1 TAOK1 KLC1

9.63e-061991096f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ComputationalAcetylCholine receptors.

GLRA3 GLRA1 GLRA2

4.43e-0514553MODULE_328
ComputationalNeurotransmitter (GABA) receptor.

GLRA3 GLRA1 GLRA2

5.52e-0515553MODULE_215
ComputationalGenes in the cancer module 267.

GLRA3 GLRA1 GLRA2

5.52e-0515553MODULE_267
ComputationalIon channels.

GLRA3 GLRA1 GLRA2

3.40e-0427553MODULE_214
ComputationalNeighborhood of BUB1B

NSD2 MRPS18B RFC3 PLAGL2

3.49e-0466554MORF_BUB1B
Drugip 0

GLRA3 THRB GLRA1 GLRA2

1.37e-07111054CID000006943
Drugcolchicoside

GLRA3 PPIG GLRA1 GLRA2

2.05e-07121054CID000092763
Drugprotostrychnine

GLRA3 GLRA1 GLRA2

3.80e-0741053CID005320746
Drug7-nitroindoline

GLRA3 GLRA1 GLRA2

3.80e-0741053CID013566747
DrugSC-49648

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000195696
Drugakuammiline

GLRA3 GLRA1 GLRA2

3.80e-0741053CID005367018
DrugN-methyl-THIP

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000134373
DrugSC-48981

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000126573
Drugiso-THAZ

GLRA3 GLRA1 GLRA2

3.80e-0741053CID003047783
Drug2-(phosphonomethyl)phenylalanine

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000383689
DrugNSC381080

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000165497
DrugSC-50132

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000195719
DrugSR 42641

GLRA3 GLRA1 GLRA2

3.80e-0741053CID000129049
DrugLindane

GLRA3 GLRA1 GLRA2

9.47e-0751053DB00431
Drugpleiocarpamine

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000558637
Drugazetidine-3-carboxylic acid

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000093192
DrugCao C

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000166617
Drugoxanilide

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000069288
Drugiso-THAO

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000127199
DrugALX1393

GLRA3 GLRA1 GLRA2

9.47e-0751053CID016078939
Drugmafoprazine

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000071241
Druggevotroline

GLRA3 GLRA1 GLRA2

9.47e-0751053CID000060546
DrugTHAZ

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000171289
Drugthiomuscimol

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000005448
Drugthio-THIP

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000656720
DrugAC1L90PQ

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000436036
DrugmV GABA

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000128435
Drugcaged glycine

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000192642
Drugbrometone

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000006424
Drugminaxolone

GLRA3 GLRA1 GLRA2

1.89e-0661053CID000071960
DrugL-serinamide

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000101138
DrugBoc-glycine

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000078288
Drugalpha-EMTBL

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000128423
DrugCID189778

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000189778
Drugpropyl methanethiosulfonate

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000529387
Drugthiocolchicoside

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000072067
DrugPK 8165

GLRA3 GLRA1 GLRA2

3.29e-0671053CID000071219
DrugWT702

GLRA3 GLRA1 GLRA2

5.25e-0681053CID000089643
Drugisostrychnine

GLRA3 GLRA1 GLRA2

5.25e-0681053CID000264626
DrugNSC129536

GLRA3 GLRA1 GLRA2

7.85e-0691053CID000004815
DrugAtonik

GLRA3 GLRA1 GLRA2

7.85e-0691053CID000069471
Drugnortropanol

GLRA3 GLRA1 GLRA2

7.85e-0691053CID000068147
DrugAC1NSJX8

GLRA3 GLRA1 GLRA2

7.85e-0691053CID005311059
DrugSR 57227A

GLRA3 GLRA1 GLRA2

7.85e-0691053CID000131746
DrugDCQX

GLRA3 GLRA1 GLRA2

7.85e-0691053CID000001845
DrugAC1NUW3V

GLRA3 APOH GLRA1 GLRA2

9.28e-06291054CID005462126
Drugbilobalide

GLRA3 PPIG GLRA1 GLRA2

1.07e-05301054CID000073581
DrugTHBA

GLRA3 GLRA1 GLRA2

1.12e-05101053CID000130993
DrugNPC 12626

GLRA3 BTC GLRA1 GLRA2

1.22e-05311054CID000108099
DrugABPH

GLRA3 GLRA1 GLRA2

3.34e-05141053CID000092377
Drugquinoxaline-2,3-dione

GLRA3 GLRA1 GLRA2

3.34e-05141053CID011469229
DrugProcyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A

EML4 ZNF254 CPM RFC3 NEIL3 ZNF107 ZNF669

3.87e-0519910574817_DN
DrugACEA-1011

GLRA3 GLRA1 GLRA2

4.17e-05151053CID000127872
Drugmilacemide

GLRA3 GLRA1 GLRA2

4.17e-05151053CID000053568
DrugLY233536

GLRA3 GLRA1 GLRA2

5.11e-05161053CID000126239
Drug7-Cl-Thio-Kyna

GLRA3 GLRA1 GLRA2

6.18e-05171053CID003035668
Drugzatosetron

GLRA3 GLRA1 GLRA2

6.18e-05171053CID000060763
Drugcyanotriphenylborate

GLRA1 GLRA2

6.30e-0531052CID000151925
Drug7-chloro-4-quinolinol

GLRA1 GLRA2

6.30e-0531052CID000066593
DrugMNQX

GLRA3 GLRA1 GLRA2

7.39e-05181053CID000130818
DrugAC1L1CMQ

GLRA3 GLRA1 GLRA2

8.75e-05191053CID000001968
DrugPNU-120596

GLRA3 GLRA1 GLRA2

8.75e-05191053CID000311434
Drugpropanethiol

GLRA3 GLRA1 GLRA2

1.03e-04201053CID000007848
Drugdi-Z

GLRA3 GLRA1 GLRA2

1.03e-04201053CID000656933
Drugethyltrimethylammonium

GLRA3 GLRA1 GLRA2

1.19e-04211053CID000033993
Drugmeproadifen

GLRA3 GLRA1 GLRA2

1.19e-04211053CID000189752
DrugR 5135

GLRA3 GLRA1 GLRA2

1.19e-04211053CID000119544
DrugPicrotoxin

GLRA3 GLRA2

1.26e-0441052DB00466
DrugZ-Gly

GLRA3 GLRA1 GLRA2

1.38e-04221053CID000014349
Drug1-chloro-1,2,2-trifluorocyclobutane

GLRA3 GLRA1 GLRA2

1.80e-04241053CID000079091
DrugSL 75102

GLRA3 GLRA1 GLRA2

1.80e-04241053CID005751746
DrugMitoxantrone dihydrochloride [70476-82-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZNF254 PLEKHG3 PLAGL2 NEIL3 ZNF107 ZNF292

2.07e-0418310563232_DN
DrugV-X-A

GLRA3 GLRA1 GLRA2

2.29e-04261053CID006369389
DrugSulfaphenazole [526-08-9]; Up 200; 12.8uM; PC3; HT_HG-U133A

DSP NSD2 USP24 THRB C1QTNF1 AKAP7

2.32e-0418710561794_UP
Drugpitrazepin

GLRA3 GLRA1 GLRA2

2.57e-04271053CID000146222
DrugL-689,560

GLRA3 GLRA1 GLRA2

2.57e-04271053CID000121918
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; PC3; HT_HG-U133A

NSD2 ZNF254 USP24 ZNF34 NFKB2 ZNF107

2.68e-0419210562101_DN
DrugLynestrenol [52-76-6]; Down 200; 14uM; PC3; HT_HG-U133A

CCNJL NSD2 EML4 WT1 AKAP7 ZNF44

2.83e-0419410566756_DN
DrugBN52020

GLRA3 GLRA1 GLRA2

2.87e-04281053CID000115221
DrugSulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A

USP24 RFC3 PREPL ZNF419 NFRKB AKAP7

2.91e-0419510561815_UP
DrugCisapride [81098-60-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A

ZNF586 ZNF571 THAP1 PLAGL2 NEIL3 ZNF292

2.91e-0419510565305_DN
DrugBetaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ZNF586 LZTR1 VPS13C ZNF571 NFKB2 TMPRSS3

2.99e-0419610563208_DN
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A

RTEL1 KLC2 NFKB2 NFRKB ZNF721 AKAP7

2.99e-0419610564645_DN
DrugSulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A

CCNJL NSD2 EML4 USP24 ZNF34 THRB

2.99e-0419610561810_UP
Drugprochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A

NSD2 WT1 CLSTN1 NFRKB NEIL3 PUS7

2.99e-0419610561156_DN
DrugNapelline [5008-52-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A

LZTR1 RTEL1 ZNF34 PLEKHG3 NFKB2 ZNF292

3.08e-0419710566824_DN
Drug(+,-)-Synephrine [94-07-5]; Down 200; 24uM; PC3; HT_HG-U133A

WT1 KLC2 THAP1 ZFP36 ZNF107 AKAP7

3.08e-0419710567150_DN
Drugfelbamate

GLRA3 PPIG GLRA1 GLRA2

3.10e-04701054CID000003331
DrugAsp-Amp

GLRA1 GLRA2

3.12e-0461052CID000146213
DrugDB06918

RTEL1 APOH

3.12e-0461052CID009547940
DrugNadide [53-84-9]; Down 200; 6uM; HL60; HT_HG-U133A

OTUB1 CPM APOH GLRA1 AKAP7 ZNF44

3.16e-0419810562529_DN
DrugClonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A

SCRN3 RTEL1 ZNF34 NFKB2 PLAGL2 AKAP7

3.25e-0419910566814_DN
DrugIodipamide [606-17-7]; Down 200; 3.6uM; MCF7; HT_HG-U133A

ZNF586 OTUB1 ZNF254 RFC3 HIVEP3 NEIL3

3.25e-0419910566490_DN
DrugGlycine

GLRA3 GLRA1 GLRA2

3.53e-04301053DB00145
DrugBlue Shield

GLRA3 GLRA1 GLRA2

3.53e-04301053CID000014830
DiseaseWriter's Cramp

THAP1 GLRA1

2.09e-047942C4316810
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

KLC2 KLC1

2.09e-047942DOID:0080348 (implicated_via_orthology)
DiseaseDystonia Disorders

THAP1 GLRA1

2.09e-047942C0393593
DiseaseIdiopathic familial dystonia

THAP1 GLRA1

2.09e-047942C0393598
DiseaseAdult-Onset Idiopathic Focal Dystonias

THAP1 GLRA1

2.09e-047942C0752198
DiseaseAdult-Onset Dystonias

THAP1 GLRA1

2.09e-047942C0752197
DiseaseAdult-Onset Idiopathic Torsion Dystonias

THAP1 GLRA1

2.09e-047942C0752199
DiseaseAutosomal Dominant Familial Dystonia

THAP1 GLRA1

2.09e-047942C0752200
DiseaseChildhood Onset Dystonias

THAP1 GLRA1

2.09e-047942C0752202
DiseaseAutosomal Recessive Familial Dystonia

THAP1 GLRA1

2.09e-047942C0752201
DiseaseDystonia, Primary

THAP1 GLRA1

2.09e-047942C0752203
DiseaseDystonias, Sporadic

THAP1 GLRA1

2.09e-047942C0752206
DiseaseDystonia, Secondary

THAP1 GLRA1

2.09e-047942C0752205
DiseasePseudodystonia

THAP1 GLRA1

2.09e-047942C0752208
DiseaseFamilial Dystonia

THAP1 GLRA1

2.09e-047942C0752207
DiseaseFocal Dystonia

THAP1 GLRA1

2.09e-047942C0743332
Diseaseidiopathic pulmonary fibrosis

ACTRT3 RTEL1 DSP

8.09e-0457943EFO_0000768
DiseaseHamman-Rich syndrome

RTEL1 DSP

8.91e-0414942C0085786
DiseaseMicrocephaly

NSD2 PUS7 ZNF292

1.29e-0367943C0025958
Diseaselevel of Sphingomyelin (d34:1) in blood serum

USP24 BTC

1.49e-0318942OBA_2045175
DiseaseUsual Interstitial Pneumonia

RTEL1 DSP

1.66e-0319942C4721509
DiseaseHamman-Rich Disease

RTEL1 DSP

1.66e-0319942C4721508
DiseaseCongenital Myasthenic Syndromes, Presynaptic

MYO9A PREPL

1.66e-0319942C0751884
DiseaseFamilial Idiopathic Pulmonary Fibrosis

RTEL1 DSP

1.84e-0320942C4721952
DiseaseIdiopathic Pulmonary Fibrosis

RTEL1 DSP

2.03e-0321942C1800706
DiseaseIntellectual Disability

MYT1L NSD2 PREPL TAOK1 PUS7 ZNF292

3.10e-03447946C3714756
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

USP24 BTC

3.10e-0326942OBA_2045191
DiseaseUterine leiomyoma

ACTRT3 WT1 THRB

3.11e-0391943HP_0000131

Protein segments in the cluster

PeptideGeneStartEntry
KPTLYYKDKATFGCH

APOH

221

P02749
KHIYDYNLKLKPCDG

ACTRT3

86

Q9BYD9
LKKKQSNGYYHCESS

AKAP7

266

Q9P0M2
YCDKPPSKYIAKRKH

FAM47DP

21

A6NHR8
TPTRGYFENKKKCHA

APOBEC3H

41

Q6NTF7
CPRKTKECLKEYAHY

CCNJL

221

Q8IV13
HQYKLTVTAYDCGKK

CLSTN1

231

O94985
KDLRYCTKHYNTGKF

GLRA3

226

O75311
YDERGKKVKCTAPQY

MOB2

96

Q70IA6
YCDKPPSKYFAKRKH

FAM47C

21

Q5HY64
QFLYTDKIKYPRKGH

LZTR1

526

Q8N653
HYEKDPCVKYDIGRK

NFRKB

631

Q6P4R8
ALSKHYKVYKRPNCG

NEIL3

241

Q8TAT5
SSYSCGRKKKVNPYE

MGME1

31

Q9BQP7
GKFYHEACVKKYPLT

NSD2

736

O96028
YCDKPPSKYFAKRKH

FAM47B

21

Q8NA70
LKKPIYQKTACYGHF

MAT1A

366

Q00266
KHYYSKACRLNPALA

LRP2BP

321

Q9P2M1
RKIIKYDPSKYCHNL

NOL8

161

Q76FK4
YDPSKYCHNLKKIGE

NOL8

166

Q76FK4
LYGKRGKYKEAEPLC

KLC2

291

Q9H0B6
HYGCASIIYLRPKSK

OR10T2

251

Q8NGX3
GKSTQKPLHYKSCLF

PPIG

51

Q13427
HKKYSYIRKTRPDGN

OTUB1

76

Q96FW1
CKSHYAAFSVGRKKP

C1QTNF1

141

Q9BXJ1
DRKHICPYRTNKYGE

CPM

336

P14384
YLKGLQDSIRKKYPC

DSP

391

P15924
LTDGPINYKYKTKCT

ATRNL1

106

Q5VV63
LEKYTKVKCGYATLH

EDEM1

521

Q92611
EKELGYCTKHYNTGK

GLRA2

226

P23416
LSKRIAPCYQDYVKK

ITGA4

176

P13612
HSCPKMKYKGQYRPS

ATE1

411

O95260
LDKPGKSRDFYHTCY

FNTB

351

P49356
KPKSSAHYYKQIIRE

KLB

491

Q86Z14
FQYPCSKAKAPSHKY

EML4

816

Q9HC35
ARYKYCPDIKEKGLS

GADL1

191

Q6ZQY3
GSYPKYKHHCAKILS

GTF2IRD2

896

Q86UP8
GSYPKYKHHCAKILS

GTF2IRD2B

896

Q6EKJ0
FSRCPKQYKHYCIKG

BTC

66

P35070
LYGKRGKYKEAEPLC

KLC1

306

Q07866
EISYPKGKCSTYQIK

PTPN13

2016

Q12923
DKYRPCSLGRLDYHK

RFC3

6

P40938
HCSSYKGYICKRPKI

MRC1

1346

P22897
DLVKSGSKHRVCPYY

RTEL1

196

Q9NZ71
VKEKYAKYLPHSAGR

RPS5

41

P46782
KKRGDHFVYKGNIPC

PLEKHG3

331

A1L390
SSGRYCEGYKLLNKH

SCRN3

236

Q0VDG4
KDLRYCTKHYNTGKF

GLRA1

221

P23415
PKSRGSYCHFVLYKE

PUS7

251

Q96PZ0
YPEKSRGCLKKAYDL

SLC5A4

591

Q9NY91
QRIKHPNSIEYKGCY

TAOK1

81

Q7L7X3
PQLHCGKAFASKYKL

PLAGL2

71

Q9UPG8
KKNKYRPISHTPSYC

RITA1

96

Q96K30
VYHSKYKPKRLGNDI

TMPRSS3

291

P57727
YAPYTGVCVKQHKRL

MRPS18B

136

Q9Y676
KEHLKIHTGYKPYSC

ZBTB14

321

O43829
YGEKPYTHKQRGKAI

ZNF823

131

P16415
NHRKIYSGEKPYKCE

ZNF107

401

Q9UII5
QKIHTGVKPYKCYDC

ZNF624

631

Q9P2J8
SKLHYKPNRYFKCEN

ZNF414

166

Q96IQ9
KPYKCDVCHKSFRYG

ZFP28

531

Q8NHY6
PYECSKYGKLFHQKP

ZNF586

121

Q9NXT0
RTHSGKKPYECKQYG

ZNF700

326

Q9H0M5
LRENKPCIKYTGHYF

TM2D2

136

Q9BX73
HKRTHTGEKPYECKY

ZNF441

326

Q8N8Z8
YYKSIHTGEKPYKCE

ZNF676

186

Q8N7Q3
SHTGYELFEKPYKCK

ZNF791

121

Q3KP31
CGKKYTRKDQLEYHI

ZBTB37

406

Q5TC79
IHTGEKPYECSKYEK

ZNF19

406

P17023
TSGKYPNCRYKEKHL

RNASE8

111

Q8TDE3
NEYKKIHTGDKPYKC

ZNF721

421

Q8TF20
QKNLHPSYSCKYEGK

THRB

136

P10828
SAYGCKNRYDKDKPV

THAP1

6

Q9NVV9
KYKTELCHKFYLQGR

ZFP36

141

P26651
PYSLKRGKHVYSIKA

ZNF292

2356

O60281
HKKYYCSELQIAKPI

HIVEP3

661

Q5T1R4
RIHNYEKPYKCSKCE

ZNF322

91

Q6U7Q0
KPYKYHDCGKVFSQA

ZNF137P

126

P52743
TYHKRTHTGEKPYKC

ZNF716

396

A6NP11
AYPGCNKRYFKLSHL

WT1

326

P19544
TYRYHCAIPGSKKTI

VPS13C

3631

Q709C8
SSDEKHKNYIKRYCP

PREPL

611

Q4J6C6
QKHYICPIKKAASYH

TRIM60

126

Q495X7
LKPKDAGRYFCAYKT

VSTM1

86

Q6UX27
RSHTKEKPYKCYECG

ZNF347

281

Q96SE7
TKLKHPYYPCMAKVS

USP24

2151

Q9UPU5
DRYKTRHTGKKPFQC

ZNF429

161

Q86V71
KLIHTREKPYKCEQY

ZNF493

156

Q6ZR52
THTGEKPYECKLYGK

ZNF491

236

Q8N8L2
TIYKKIHAGEKPYNC

ZNF355P

251

Q9NSJ1
RKHQIIYLGGKQYKC

ZNF860

246

A6NHJ4
DKCPKAFKSSYHLIR

ZNF674

311

Q2M3X9
GYAGPYKHTKDKLLC

SLC27A6

436

Q9Y2P4
RPYKCSECGKFYSHK

ZNF419

341

Q96HQ0
SHSKSQLCRYPKYKN

ZNF425

211

Q6IV72
QKAKLYCAPIKGHSY

TRBV16

36

A0A087WV62
YHQRIHTGEKPYKCK

ZNF571

491

Q7Z3V5
SECGKYFGHKYRLIK

ZNF772

381

Q68DY9
EKSYTHKQCGKGLSY

ZNF44

186

P15621
HAGEKPYKCREYYKG

ZNF214

576

Q9UL59
TNHRKIYTEEKPYKC

ZNF254

226

O75437
RHTGDKPYEYKDCGK

ZNF560

621

Q96MR9
HSGYKPYGEKQYKCE

ZNF669

211

Q96BR6
DQKIPTGKKLHYCSY

ZNF34

241

Q8IZ26
YCKKGFRRPSEKNQH

ZFY

776

P08048
KDKRKHCGYTQLSPF

USP54

591

Q70EL1
PQLYKYLSQGHCAKE

MYO1H

226

Q8N1T3
ILHLGNICYKKKTYR

MYO9A

426

B2RTY4
YARHRSVYGCPLAKK

MYT1L

46

Q9UL68
EKGRKTYPTVKICNY

NFKB2

71

Q00653