Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein dephosphorylation

PTPN9 FCRL3 SBF1 MFHAS1 MTOR PPP1R2C PTPRU

9.21e-06256607GO:0006470
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

2.49e-053602GO:0071228
GeneOntologyBiologicalProcessdephosphorylation

PTPN9 FCRL3 SBF1 MFHAS1 MTOR PPP1R2C PTPRU

6.45e-05347607GO:0016311
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH2 NOTCH3

8.98e-0530603GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH2 NOTCH3

9.93e-0531603GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH2 NOTCH3

9.93e-0531603GO:0061437
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

1.24e-046602GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

1.24e-046602GO:0072104
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

1.73e-047602GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

1.73e-047602GO:0061439
MousePhenoabnormal mononuclear phagocyte morphology

MPO KL TRIB2 MTOR PIK3CG CCR4 ABCD2 SLC48A1 NOTCH2 NOTCH3 OCSTAMP

2.03e-057054811MP:0008248
MousePhenoabnormal macrophage morphology

KL TRIB2 PIK3CG CCR4 ABCD2 SLC48A1 NOTCH2 NOTCH3 OCSTAMP

2.36e-05463489MP:0002446
MousePhenoabnormal phagocyte morphology

MPO KL TRIB2 METRN SBF1 MTOR PIK3CG CCR4 ABCD2 SLC48A1 NOTCH2 NOTCH3 OCSTAMP

3.06e-0510334813MP:0008251
MousePhenodecreased thymocyte number

MTOR PIK3CG NOTCH1 NOTCH3 DNMT3B

7.16e-05127485MP:0000715
MousePhenodecreased skeletal muscle weight

MYH3 MTOR RYR1

7.31e-0524483MP:0010239
MousePhenoabnormal myeloid leukocyte morphology

MPO KL TRIB2 METRN SBF1 MTOR PIK3CG CCR4 HAS1 ABCD2 SLC48A1 NOTCH2 NOTCH3 OCSTAMP

7.37e-0512924814MP:0008250
MousePhenoabnormal respiratory motile cilium morphology

CFAP54 DNAH5 DNAH9

1.30e-0429483MP:0011050
MousePhenoabnormal skeletal muscle weight

MYH3 MTOR RYR1

1.30e-0429483MP:0010237
MousePhenoabnormal professional antigen presenting cell morphology

KL TRIB2 MTOR PIK3CG CCR4 ABCD2 SLC48A1 NOTCH2 NOTCH3 OCSTAMP

1.45e-047264810MP:0008195
MousePhenodecreased skeletal muscle size

MYH3 MTOR RYR1 NOTCH3

1.68e-0481484MP:0010240
MousePhenodomed cranium

PTPN9 CFAP54 DNAH5 RYR1

2.02e-0485484MP:0000440
MousePhenodecreased muscle weight

MYH3 MTOR RYR1

2.11e-0434483MP:0004232
MousePhenocalcified aortic valve

KL NOTCH1

2.40e-047482MP:0006116
MousePhenoabnormal skeletal muscle size

MYH3 MTOR RYR1 NOTCH3

2.86e-0493484MP:0009458
MousePhenoabnormal macrophage cell number

KL PIK3CG CCR4 SLC48A1 NOTCH2 NOTCH3

3.57e-04278486MP:0020202
MousePhenodecreased lymphocyte cell number

KL TRIB2 SBF1 MTOR PIK3CG ASB7 CCR4 NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.30e-049924811MP:0005016
MousePhenodecreased leukocyte cell number

KL TRIB2 SBF1 MTOR PIK3CG ASB7 CCR4 HAS1 SLC48A1 NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.35e-0413424813MP:0000221
MousePhenoabnormal muscle weight

MYH3 MTOR RYR1

4.56e-0444483MP:0004233
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.31e-083613PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2 NOTCH3

3.31e-083613IPR024600
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.31e-083613SM01334
DomainNotch

NOTCH1 NOTCH2 NOTCH3

1.32e-074613IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH3

1.32e-074613PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH3

1.32e-074613IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH3

1.32e-074613IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH3

1.32e-074613PF06816
DomainNOD

NOTCH1 NOTCH2 NOTCH3

1.32e-074613SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH3

1.32e-074613SM01339
DomainLNR

NOTCH1 NOTCH2 NOTCH3

3.30e-075613PS50258
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH3

1.15e-067613IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH3

1.15e-067613PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH3

1.15e-067613SM00004
DomainhEGF

NOTCH1 NOTCH2 NOTCH3

1.02e-0428613PF12661
Domain2OG-FeII_Oxy_2

ALKBH7 ALKBH6

2.18e-047612PF13532
DomainDHC_N1

DNAH5 DNAH9

2.90e-048612PF08385
DomainAlkB-like

ALKBH7 ALKBH6

2.90e-048612IPR027450
DomainDynein_heavy_dom-1

DNAH5 DNAH9

2.90e-048612IPR013594
Domain-

ALKBH7 ALKBH6

2.90e-0486122.60.120.590
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH9

9.31e-0414612IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH9

9.31e-0414612IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH9

9.31e-0414612IPR013602
DomainDHC_N2

DNAH5 DNAH9

9.31e-0414612PF08393
DomainMT

DNAH5 DNAH9

9.31e-0414612PF12777
DomainAAA_8

DNAH5 DNAH9

9.31e-0414612PF12780
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH9

9.31e-0414612IPR011704
DomainAAA_5

DNAH5 DNAH9

9.31e-0414612PF07728
DomainDHC_fam

DNAH5 DNAH9

1.07e-0315612IPR026983
DomainDynein_heavy_dom

DNAH5 DNAH9

1.07e-0315612IPR004273
DomainDynein_heavy

DNAH5 DNAH9

1.07e-0315612PF03028
DomainPI3/4_kinase_CS

MTOR PIK3CG

1.07e-0315612IPR018936
Domain-

MTOR PIK3CG

1.22e-03166121.10.1070.11
DomainPI3Kc

MTOR PIK3CG

1.22e-0316612SM00146
DomainPI3/4_kinase_cat_dom

MTOR PIK3CG

1.55e-0318612IPR000403
DomainPI3_PI4_kinase

MTOR PIK3CG

1.55e-0318612PF00454
DomainPI3_4_KINASE_3

MTOR PIK3CG

1.55e-0318612PS50290
DomainPI3_4_KINASE_1

MTOR PIK3CG

1.55e-0318612PS00915
DomainPI3_4_KINASE_2

MTOR PIK3CG

1.55e-0318612PS00916
Domain2OG-FeII_Oxy

P4HA3 ALKBH6

1.73e-0319612PF03171
DomainFE2OG_OXY

P4HA3 ALKBH6

2.12e-0321612PS51471
DomainOxoglu/Fe-dep_dioxygenase

P4HA3 ALKBH6

2.54e-0323612IPR005123
DomainEGF_CA

NOTCH1 NOTCH2 NOTCH3

2.80e-0386613PF07645
DomainTYR_PHOSPHATASE_dom

PTPN9 SBF1 PTPRU

2.89e-0387613IPR000387
DomainEGF_Ca-bd_CS

NOTCH1 NOTCH2 NOTCH3

3.93e-0397613IPR018097
DomainProt-tyrosine_phosphatase-like

PTPN9 SBF1 PTPRU

4.16e-0399613IPR029021
DomainEGF_CA

NOTCH1 NOTCH2 NOTCH3

4.16e-0399613PS01187
DomainASX_HYDROXYL

NOTCH1 NOTCH2 NOTCH3

4.28e-03100613PS00010
Domain-

CFAP54 MTOR P4HA3 NAA16

4.67e-032076141.25.40.10
DomainARM-type_fold

USP34 MTOR PIK3CG MROH2B AP1G2

4.96e-03339615IPR016024
DomainEGF-type_Asp/Asn_hydroxyl_site

NOTCH1 NOTCH2 NOTCH3

5.04e-03106613IPR000152
DomainAnk_2

ASB7 NOTCH1 NOTCH2 NOTCH3

5.34e-03215614PF12796
DomainGal_Oxidase_b-propeller

KBTBD11 KLHL26

5.50e-0334612IPR015916
DomainPTPc

PTPN9 PTPRU

6.15e-0336612SM00194
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH3

2.27e-075413M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH3

4.54e-076413M27068
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH3

3.71e-0611413M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 NOTCH3

4.93e-0612413M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH3

4.93e-0612413M47533
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

6.40e-0613413M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2 NOTCH3

6.40e-0613413M47534
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH3

1.81e-0518413M614
PathwayWP_NOTCH_SIGNALING_WP61

MTOR NOTCH1 NOTCH2 NOTCH3

2.85e-0561414M39540
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH3

4.43e-0524413M11190
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

MTOR PIK3CG NOTCH1 NOTCH2

6.12e-0574414M39857
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3

6.36e-0527413M39545
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH3

7.11e-0528413M6177
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

8.21e-055412MM14733
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH3

1.28e-0434413M39390
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3

1.72e-047412MM14734
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 NOTCH2 NOTCH3

2.98e-0445413M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

3.18e-0446413MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

3.39e-0447413M7946
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

MTOR PIK3CG PKM

3.39e-0447413M19708
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

PIK3CG NOTCH1 NOTCH2 NOTCH3

3.72e-04118414M39852
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

H2BC1 NOTCH1 NOTCH2 NOTCH3

3.84e-04119414M607
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.35e-0412412MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.35e-0412412M22042
PathwayWP_RESOLVIN_E1_AND_RESOLVIN_D1_SIGNALING_DECREASE_INFLAMMATION

MTOR PIK3CG

5.35e-0412412M45559
PathwayPID_NOTCH_PATHWAY

NOTCH1 NOTCH2 NOTCH3

6.63e-0459413M17
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

MTOR PIK3CG

8.46e-0415412M4835
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

NOTCH1 NOTCH2 NOTCH3

1.00e-0368413M27303
PathwayWP_BREAST_CANCER_PATHWAY

MTOR NOTCH1 NOTCH2 NOTCH3

1.01e-03154414M39739
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

MTOR PIK3CG

1.09e-0317412MM1353
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

PIK3CG NOTCH1

1.09e-0317412M39443
PathwayWP_INSULIN_SIGNALING

MTOR PIK3CG ARHGAP33 SGK3

1.17e-03160414MM15956
PathwayWP_INSULIN_SIGNALING

MTOR PIK3CG ARHGAP33 SGK3

1.17e-03160414M39482
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2

1.52e-0320412M27881
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

1.72e-0382413MM15922
Pubmed

NOTCH knockdown affects the proliferation and mTOR signaling of leukemia cells.

MTOR NOTCH1 NOTCH2

5.13e-09361324122995
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH2 NOTCH3

5.13e-0936138645602
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH2 NOTCH3

5.13e-09361327697639
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH2 NOTCH3

5.13e-0936137615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

5.13e-0936137918097
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH2 NOTCH3

5.13e-09361321471519
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH2 NOTCH3

5.13e-09361329767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH2 NOTCH3

5.13e-0936137698746
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461328669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461310551863
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461311401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH3

2.05e-0846138898100
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461311978185
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461317920003
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461328061457
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461324151014
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461323999936
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461310194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461318156632
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461311459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461318184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH3

2.05e-08461315917835
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 MAN2A2 SBF1 MFHAS1 MTOR KBTBD11 GEMIN5 AP1G2 ALKBH6 NOTCH1 NOTCH2 RYR1 ARHGAP33

5.00e-081105611335748872
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561319211676
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561321562564
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561311101851
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561327040987
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561321124806
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561315064243
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH2 NOTCH3

5.12e-08561323675950
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561315076712
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561312242712
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 NOTCH3

5.12e-08561315882997
Pubmed

Genetic variation in healthy oldest-old.

KL MTOR NOTCH1 DNMT3B

8.86e-082461419680556
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH2 NOTCH3

1.02e-0766139111338
Pubmed

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661326062937
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661312244553
Pubmed

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661319573812
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661318299578
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

NOTCH1 NOTCH2 NOTCH3

1.02e-0766139882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661322615412
Pubmed

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661327460529
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661320870902
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661324671051
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661322526456
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661319503073
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661311731257
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661319603167
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH1 NOTCH2 NOTCH3

1.02e-0766139108364
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH2 NOTCH3

1.02e-07661321991352
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761310383933
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761312846471
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761324711412
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761311518718
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

NOTCH1 NOTCH2 NOTCH3

1.79e-07761316169548
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

NOTCH1 NOTCH2 NOTCH3

2.86e-07861322652674
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

NOTCH1 NOTCH2 NOTCH3

2.86e-07861315465493
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH2 NOTCH3

2.86e-0786139858718
Pubmed

Notch/Delta expression in the developing mouse lung.

NOTCH1 NOTCH2 NOTCH3

2.86e-07861311044610
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH2 NOTCH3

2.86e-07861322156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH2 NOTCH3

2.86e-07861312242716
Pubmed

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.

NOTCH1 NOTCH2 NOTCH3

4.28e-07961317573339
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH2 NOTCH3

4.28e-07961311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH2 NOTCH3

4.28e-07961316245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH2 NOTCH3

4.28e-07961312370315
Pubmed

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

NOTCH1 NOTCH2 NOTCH3

4.28e-07961318507503
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH2 NOTCH3

6.11e-071061323665443
Pubmed

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.

NOTCH1 NOTCH2 NOTCH3

6.11e-071061328489825
Pubmed

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.

NOTCH1 NOTCH2 NOTCH3

6.11e-071061315525534
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

NOTCH1 NOTCH2 NOTCH3

6.11e-071061324015274
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH2 NOTCH3

6.11e-071061333915108
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH2 NOTCH3

8.39e-07116139187150
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH1 NOTCH2 NOTCH3

8.39e-071161316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH2 NOTCH3

8.39e-071161315499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 NOTCH2 NOTCH3

8.39e-071161310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 NOTCH2 NOTCH3

8.39e-071161312866128
Pubmed

The notch pathway positively regulates programmed cell death during erythroid differentiation.

MPO NOTCH1 NOTCH2 NOTCH3

1.10e-064461417476283
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH1 NOTCH2 NOTCH3

1.12e-061261315465494
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH1 NOTCH2 NOTCH3

1.12e-061261310952889
Pubmed

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

NOTCH1 NOTCH2 NOTCH3

1.12e-061261332147304
Pubmed

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.

NOTCH1 NOTCH2 NOTCH3

1.12e-061261314732396
Pubmed

Notch signaling coordinates the patterning of striatal compartments.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361316120638
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361331202705
Pubmed

Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.

DNAH5 DNAH9 NOTCH1

1.45e-061361335942101
Pubmed

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361323132245
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361332929274
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361311578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH1 NOTCH2 NOTCH3

1.45e-061361320558824
Pubmed

Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.

MTOR NOTCH1 NOTCH3

1.84e-061461321349854
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

NOTCH1 NOTCH2 NOTCH3

1.84e-061461334824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

NOTCH1 NOTCH2 NOTCH3

1.84e-061461314757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

NOTCH1 NOTCH2 NOTCH3

2.30e-061561312971992
Pubmed

FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.

MTOR NOTCH1 NOTCH2

2.30e-061561331285543
InteractionDLL1 interactions

FIBP NOTCH1 NOTCH2 NOTCH3

4.54e-0638594int:DLL1
InteractionIGSF5 interactions

NOTCH1 NOTCH2 NOTCH3

8.48e-0614593int:IGSF5
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH3

1.57e-0517593int:MAML2
InteractionMAML3 interactions

NOTCH1 NOTCH2 NOTCH3

2.62e-0520593int:MAML3
InteractionCASR interactions

NOTCH1 NOTCH2 NOTCH3

3.53e-0522593int:CASR
InteractionNTN5 interactions

NOTCH1 NOTCH2 NOTCH3

4.62e-0524593int:NTN5
InteractionMFNG interactions

MAN2A2 NOTCH1 NOTCH2

6.63e-0527593int:MFNG
InteractionZNF707 interactions

USP34 NOTCH1 NOTCH2 NOTCH3

8.45e-0579594int:ZNF707
GeneFamilyAlkylation repair homologs

ALKBH7 ALKBH6

2.06e-049442401
GeneFamilyDyneins, axonemal

DNAH5 DNAH9

7.69e-0417442536
GeneFamilyAnkyrin repeat domain containing

ASB7 NOTCH1 NOTCH2 NOTCH3

2.79e-03242444403
GeneFamilyClustered protocadherins

PCDHB5 PCDHB4

1.06e-026444220
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP

MPO MYH3 AP1G2 GRIA3 SH2B1 RPL8 ARHGAP33

4.03e-07199617M4521
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3

6.57e-0616613MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3

6.57e-0616613M2207
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ALKBH6 DNAH5 DNAH9 CFAP65

2.24e-061546159ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ALKBH6 DNAH5 DNAH9 CFAP65

2.24e-0615461558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP54 KCNK12 DNAH5 DNAH9 CFAP65

4.43e-061776153cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP54 KCNK12 DNAH5 DNAH9 CFAP65

4.43e-0617761512a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellHSPCs-Mono_prog.|World / Lineage and Cell class

MPO PKM GRIA3 KCNK12 ABCD2

5.21e-061836151b73070baa9e5d5ada4ce25a77741630af9c1a3a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 METRN DNAH5 DNAH9 CFAP65

6.75e-06193615e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellsevere-Lymphocytic-CD4_T_cells_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TRIB2 FCRL3 MFHAS1 CCR4 RPL8

7.10e-0619561590136f65e3e72cf2b2e0a13b48a7c9d60628b396
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

CFAP54 KCNK12 DNAH5 DNAH9 CFAP65

7.46e-06197615fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

CFAP54 DNAH5 DNAH9 ARHGAP33 CFAP65

7.64e-061986156d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellSigmoid-T_cell-Tfh|T_cell / Region, Cell class and subclass

MYH3 CFAP54 TRIB2 KBTBD11 NOTCH1

8.02e-06200615dd7dcf25520f065bf0d33d589f3c176f63875dc9
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHB5 PCDHB4 RYR1 DNMT3B

1.32e-05105614c7528276fee8f6d2cb4639069bc87413b0288025
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHB5 PCDHB4 RYR1 DNMT3B

1.32e-051056147bcf3345a21a1ade717128be127e9fe12ae40011
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHB5 PCDHB4 RYR1 DNMT3B

1.32e-0510561462e89b92bb8c5187ab0205aebd018b4178710bb0
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCNK12 DNAH9 RYR1 CFAP65

4.56e-0514461408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

5.07e-05148614d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

5.07e-05148614c8e93b87212f55774223caa385859c566fa1981f
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

5.92e-051546144e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

5.92e-051546147556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

6.07e-051556145f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

6.07e-051556140944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellCD8+_Memory_T_cell-RSV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

FCRL3 P2RY11 PKM SLC48A1

7.03e-05161614f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 DNAH5 DNAH9 CFAP65

7.55e-05164614e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM132E GEMIN5 KCNK12 RYR1

7.73e-051656141b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM132E GEMIN5 KCNK12 RYR1

7.73e-05165614b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CFAP54 METRN DNAH5 DNAH9

8.10e-0516761426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 DNAH5 DNAH9 CFAP65

8.48e-0516961414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 NOTCH1 NOTCH3 DNMT3B

9.50e-051746140fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 NOTCH1 NOTCH3 DNMT3B

9.50e-05174614b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-Treg|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TRIB2 FCRL3 CCR4 ABCD2

9.92e-051766142eb1827171e9c19f945e87824215721f8cf22258
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 DNAH5 DNAH9 CFAP65

9.92e-05176614dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 NOTCH1 NOTCH3 DNMT3B

9.92e-05176614d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 DNAH9 NOTCH3 CFAP65

1.01e-04177614e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 DNAH5 DNAH9 CFAP65

1.01e-04177614ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCelldroplet-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO GRIA3 KCNK12 ABCD2

1.01e-041776145f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 DNAH5 DNAH9 CFAP65

1.01e-04177614bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO GRIA3 KCNK12 ABCD2

1.04e-04178614be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 DNAH5 DNAH9 CFAP65

1.04e-04178614de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 DNAH5 DNAH9 CFAP65

1.06e-041796145e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIB2 KBTBD11 CCR4 RPL8

1.08e-0418061403e3067ee313e8c40b702b9bc9981f9859d045a2
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK12 DNAH5 DNAH9 CFAP65

1.08e-04180614cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 DNAH5 DNAH9 CFAP65

1.08e-04180614bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO RNF112 KCNK12 RYR1

1.08e-041806146ac62bf1251978c8c12e715f7b73144fca619794
ToppCell(2)_NK/T-(230)_CD4+/CD25+_Reg_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

TRIB2 FCRL3 CCR4 RPL8

1.11e-04181614ad14c7111d4fb924afd233cb114447f195373a7c
ToppCellHSPCs-Mono_prog.|HSPCs / Lineage and Cell class

MPO PKM GRIA3 ABCD2

1.11e-04181614a188f0d22426d8723ba394d94d20431afa6722a7
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.11e-041816141ea21d860d4d7abab3e21e130a16d044006656ee
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIB2 KBTBD11 CCR4 RPL8

1.11e-041816148bab8be68611e49c8aad39b4df0ba0f1c143d118
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.11e-0418161460a91587c59029a34e7bec1255083337fe21b72a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 DNAH5 DNAH9 CFAP65

1.11e-04181614c1b1e62440805800a3a600b1ddd79be1c9762598
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 DNAH5 DNAH9 CFAP65

1.11e-04181614dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP54 DNAH5 DNAH9 CFAP65

1.13e-04182614fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

METRN DNAH5 DNAH9 CFAP65

1.15e-0418361458847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.18e-04184614a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO AP1G2 GRIA3 DNMT3B

1.18e-04184614185b49630da61cbf45c0926d1b992943296d2a54
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.18e-04184614ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.18e-04184614797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.18e-0418461477d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 DNAH5 DNAH9 CFAP65

1.20e-0418561405bc89a566b0db90ae06506e067190a4739a0974
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO KCNK12 PTPRU ABCD2

1.20e-0418561453854a9ec87c24c360541c83d86d8fafb303ad58
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO KCNK12 PTPRU ABCD2

1.20e-04185614a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 DNAH5 DNAH9 CFAP65

1.20e-041856145e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell(230)_CD4+/CD25+_Reg_T_cell|World / immune cells in Peripheral Blood (logTPM normalization)

TRIB2 FCRL3 CCR4 RPL8

1.20e-04185614f846166cec84985d6a09a45d045acd686174b6d9
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 DNAH5 DNAH9 CFAP65

1.20e-041856143e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP54 DNAH5 DNAH9 CFAP65

1.20e-0418561418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 DNAH5 DNAH9 CFAP65

1.23e-0418661476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP54 DNAH5 DNAH9 CFAP65

1.25e-04187614f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO AP1G2 GRIA3 DNMT3B

1.25e-04187614e53471c3e146a6f54788d81ecc469aba55b051bb
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP1B1 OLFML2B P4HA3 HAS1

1.25e-041876140d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO AP1G2 GRIA3 DNMT3B

1.25e-041876143d7d51fbadb20dc884d0b3c0d61b80f022b19d09
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.25e-04187614a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 DNAH5 DNAH9 CFAP65

1.25e-041876149e10ed56090d82589bc457788282f664b70ace4b
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

GEMIN5 PTPRU MED23 KLHL26

1.28e-04188614c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

CFAP54 DNAH5 DNAH9 CFAP65

1.28e-041886148f30535a32968a81a304315a49c0d90a77d36948
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

GEMIN5 PTPRU MED23 KLHL26

1.28e-041886149155b9a92496e75646778c025b02947e9e9ec73a
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DNAH5 DNAH9 CFAP65

1.28e-04188614e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614b55de812043b670cbde810d7d42f45909b6d66ef
ToppCelldroplet-Marrow-BM-1m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO GRIA3 KCNK12 DNMT3B

1.31e-04189614b81540e097e95158851e07bfd78640ed6e64c2cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-0418961402c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614407d8a59969d83f014600aae1a55092283a13970
ToppCelldroplet-Marrow-BM-1m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO GRIA3 KCNK12 DNMT3B

1.31e-041896140fda1a3f1e87fadf5309c8267beaa4501983b1dd
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-041896140bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

METRN OLFML2B RPL8 NOTCH3

1.31e-041896149c2492c38f27e4c699b40680652e4c64911cce52
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-041896149f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-0418961427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-041896144e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.31e-04189614e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellHSPCs-Gran/Mono_prog.|World / Lineage and Cell class

MPO PKM GRIA3 KCNK12

1.33e-0419061494547c1cc2c3f2ac28a6d07317e50e1e3fd20267
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.33e-04190614088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.33e-0419061435248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.33e-041906145f5206f9e725070d865f4c891ff08bb750e58582
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.36e-04191614acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.36e-04191614bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellHSPCs-Gran/Mono_prog.|HSPCs / Lineage and Cell class

MPO PKM GRIA3 KCNK12

1.36e-0419161454620502e6aea0a615b664e861e0044dd9e0ad91
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP54 DNAH5 DNAH9 CFAP65

1.36e-041916146880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 DNAH5 DNAH9 CFAP65

1.36e-04191614e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 DNAH5 DNAH9 CFAP65

1.36e-041916149d31c8424d35bdc0c27188b68bfd0f731af3600b
Drugbaicalein

MPO CYP1B1 MTOR PKM NOTCH1

3.36e-0687605ctd:C006680
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.13e-077553DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.13e-077553DOID:3620 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

MTOR NOTCH1 NOTCH2

2.74e-0615553C0496930
DiseaseBenign neoplasm of bladder

MTOR NOTCH1 NOTCH2

2.74e-0615553C0154017
DiseaseCarcinoma in situ of bladder

MTOR NOTCH1 NOTCH2

2.74e-0615553C0154091
DiseaseCarcinoma of bladder

MTOR NOTCH1 NOTCH2

4.90e-0618553C0699885
DiseaseGlioblastoma

MTOR NOTCH1 NOTCH2 NOTCH3

1.46e-0579554C0017636
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.55e-0526553DOID:1319 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

MTOR NOTCH1 NOTCH2 NOTCH3

1.87e-0584554C0334588
DiseaseMultiple pterygium syndrome

MYH3 RYR1

2.04e-054552C0265261
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.40e-0530553DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.93e-0532553DOID:10155 (implicated_via_orthology)
Diseasecervical cancer

MTOR NOTCH1 NOTCH2

3.52e-0534553C4048328
DiseaseUterine Cervical Neoplasm

MTOR NOTCH1 NOTCH2

3.84e-0535553C0007873
DiseaseGlioblastoma Multiforme

MTOR NOTCH1 NOTCH2 NOTCH3

5.58e-05111554C1621958
DiseaseSquamous cell carcinoma

CYP1B1 NOTCH1 NOTCH2 NOTCH3

8.58e-05124554C0007137
DiseaseBladder Neoplasm

MPO MTOR NOTCH1 NOTCH2

1.37e-04140554C0005695
DiseaseMalignant neoplasm of urinary bladder

MPO MTOR NOTCH1 NOTCH2

1.41e-04141554C0005684
DiseaseMalignant neoplasm of breast

CYP1B1 FCRL3 MTOR DNAH9 NOTCH1 NOTCH2 NOTCH3 DNMT3B SGK3

1.53e-041074559C0006142
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH2 NOTCH3

1.85e-0459553C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH2 NOTCH3

1.85e-0459553C0037286
DiseaseQRS duration

USP34 MFHAS1 OLFML2B KBTBD11 NOTCH2

2.34e-04298555EFO_0005055
Diseasemyocardial infarction (implicated_via_orthology)

CYP1B1 MTOR RYR1

2.58e-0466553DOID:5844 (implicated_via_orthology)
DiseaseSitus ambiguus

DNAH5 DNAH9

3.53e-0415552C0266642
DiseaseLiver carcinoma

MPO MTOR OLFML2B KBTBD11 PKM NOTCH3

3.55e-04507556C2239176
Diseasecentral nervous system disease (implicated_via_orthology)

GEMIN5 GRIA3

4.03e-0416552DOID:331 (implicated_via_orthology)
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

MTOR NOTCH1

4.03e-0416552C0334634
DiseaseMammary Carcinoma, Human

CYP1B1 MTOR NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.27e-04525556C4704874
DiseaseMammary Neoplasms, Human

CYP1B1 MTOR NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.27e-04525556C1257931
DiseaseMammary Neoplasms

CYP1B1 MTOR NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.36e-04527556C1458155
Diseaseelectrocardiography

TRIB2 MFHAS1 OLFML2B KBTBD11 SLC48A1 SGK3

4.49e-04530556EFO_0004327
Diseasealcohol use disorder (implicated_via_orthology)

NOTCH1 NOTCH2 RYR1 NOTCH3

4.85e-04195554DOID:1574 (implicated_via_orthology)
DiseaseBreast Carcinoma

CYP1B1 MTOR NOTCH1 NOTCH2 NOTCH3 DNMT3B

4.86e-04538556C0678222
DiseaseSquamous cell carcinoma of esophagus

NOTCH1 NOTCH2 NOTCH3

7.51e-0495553C0279626
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3

9.17e-0424552C0887833
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0750936
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0334583
DiseaseAstrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0280785
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0547065
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

9.96e-0425552C0338070
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

1.08e-0326552C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

1.08e-0326552C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

1.08e-0326552C0334582
DiseaseEncephalopathies

MPO NOTCH3

1.16e-0327552C0085584
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

1.16e-0327552C0334579
Diseaseacute kidney failure (implicated_via_orthology)

MPO MTOR

1.16e-0327552DOID:3021 (implicated_via_orthology)
Diseaselung small cell carcinoma (is_implicated_in)

MTOR DNMT3B

1.25e-0328552DOID:5409 (is_implicated_in)
DiseaseLung Neoplasms

MPO CYP1B1 NOTCH2 NOTCH3

1.51e-03265554C0024121
DiseaseMalignant neoplasm of lung

MPO CYP1B1 NOTCH2 NOTCH3

1.53e-03266554C0242379
Diseasecancer (implicated_via_orthology)

MTOR NOTCH1 NOTCH2 NOTCH3

1.58e-03268554DOID:162 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
AYTRLLHGIAAARVD

ALKBH6

176

Q3KRA9
AVALQRHRAAYSAAI

CFAP54

2311

Q96N23
RHRAAYSAAIVFSTL

CFAP54

2316

Q96N23
LHVAAHYGRDSFVRL

ASB7

121

Q9H672
IDAIKVSAAHRARYF

DNMT3B

721

Q9UBC3
LALAFRTRLVDHAYE

ABCD2

171

Q9UBJ2
ELHAYSVRRLYNALA

AP1G2

451

O75843
YLAIVHAVFSLRART

CCR4

136

P51679
HLFALRSLDYEALQA

PCDHB5

511

Q9Y5E4
FDVLRAIELFHSYRE

PTPN9

56

P43378
LEDALDHLAFAYFRA

P4HA3

226

Q7Z4N8
LHLAARYSRADAAKR

NOTCH2

1881

Q04721
DHGLAAYRAYSLVLA

P2RY11

196

Q96G91
ALHLAARYSRSDAAK

NOTCH1

1931

P46531
ARDFELRSASPHAAY

MFHAS1

581

Q9Y4C4
QEFRRAYEAARAAHL

METRN

271

Q9UJH8
LTARAHATDYFLANF

CFAP65

1616

Q6ZU64
SILAAHRATYRDYDL

PPP1R2C

51

O14990
NYLRAFHALSEAAEV

BAIAP2L2

36

Q6UXY1
HDAILVIAEAFRYLR

GRIA3

311

P42263
RAFLRHYEAALAAGV

KCNK12

91

Q9HB15
YAHVAAAVLRIRSAE

OR3A4P

221

P47883
VAATRTAVRAADYLH

MPO

106

P05164
TAVRAADYLHVALDL

MPO

111

P05164
DILRRHAFYFKAARS

NAA16

546

Q6N069
ARALVAHVRTFADFL

MED23

816

Q9ULK4
TALHLAARYARADAA

NOTCH3

1841

Q9UM47
IAREAEAAIYHLQLF

PKM

381

P14618
AARLRAVDFAERHGY

RPL8

26

P62917
HRYRADFADISILSD

SLC48A1

131

Q6P1K1
HVSRRFRTFLLDSDY

SBF1

1516

O95248
LTFEAALARGLVHYF

PTPRU

651

Q92729
HLFALRSLDYEALQA

PCDHB4

511

Q9Y5E5
VLRSYDDFRSLDAHL

ARHGAP33

96

O14559
IFERIASEASRLAHY

H2BC1

71

Q96A08
ARGLRHIIDFAYSAE

KLHL26

111

Q53HC5
RSFALEAHLYAEVDR

DBF4B

321

Q8NFT6
ALAARRHYSEAVADR

GLUD1

46

P00367
TADLRFADYLVRHVT

AVL9

471

Q8NBF6
RAQFAVYIHALLAAT

AVL9

506

Q8NBF6
SLFAYLEHRRVAAAA

HAS1

71

Q92839
VLAAAAALLHYARAR

FCRL3

586

Q96P31
RGAEVLYSLAAAHAR

MAN2A2

526

P49641
ALADHFRDYAELCFR

KL

211

Q9UEF7
HLSFARLARRYGDVF

CYP1B1

71

Q16678
LFALCYFHAVVAERR

DNAH9

4051

Q9NYC9
LQHRVESLAAFAERY

RYR1

1951

P21817
HRARFYAAEIASALG

SGK3

261

Q96BR1
ALLDARHNYLFAIVA

DNAH5

31

Q8TE73
YRAVLALHQDLFSLA

MTOR

1546

P42345
QHFLLSDRLARDYAA

FIBP

161

O43427
AAALDFARRFRLYLA

SH2B1

36

Q9NRF2
SYRLSHTRLAFFLRE

TMEM132E

46

Q6IEE7
RLLAHLYATFATADA

MYH3

616

P11055
YARRLRHAIAASFFT

OCSTAMP

421

Q9BR26
TVSLLLHREDFRGYA

MROH2B

216

Q7Z745
RSALQRDAAAAYAHP

OLFML2B

226

Q68BL8
LRAHKAVLAARSDYF

KBTBD11

151

O94819
AVLAARSDYFRARAS

KBTBD11

156

O94819
ILRGSARYDFSHEIL

ALKBH7

166

Q9BT30
LRALETSVAADFYHR

PIK3CG

76

P48736
FRHLLGAYVSDVLSA

RNF112

381

Q9ULX5
EAARLFYQIASAVAH

TRIB2

151

Q92519
NHFYREAIAIAKARL

GEMIN5

1001

Q8TEQ6
FLLAHNYPRVRTSAA

USP34

2671

Q70CQ2