Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	receptor tyrosine kinase binding	NRTN EIF3A	1.52e-03	90	13	2	GO:0030971
GeneOntologyMolecularFunction	protein tyrosine kinase binding	NRTN EIF3A	4.09e-03	149	13	2	GO:1990782
GeneOntologyCellularComponent	bicellular tight junction	MFRP C19orf84	2.91e-03	131	13	2	GO:0005923
GeneOntologyCellularComponent	tight junction	MFRP C19orf84	3.26e-03	139	13	2	GO:0070160
GeneOntologyCellularComponent	apical junction complex	MFRP C19orf84	4.19e-03	158	13	2	GO:0043296
Domain	LDLR_class-A_CS	MFRP MAMDC4	2.91e-04	40	12	2	IPR023415
Domain	Ldl_recept_a	MFRP MAMDC4	3.69e-04	45	12	2	PF00057
Domain	-	MFRP MAMDC4	3.86e-04	46	12	2	4.10.400.10
Domain	LDLRA_1	MFRP MAMDC4	4.20e-04	48	12	2	PS01209
Domain	LDLa	MFRP MAMDC4	4.38e-04	49	12	2	SM00192
Domain	LDLRA_2	MFRP MAMDC4	4.38e-04	49	12	2	PS50068
Domain	LDrepeatLR_classA_rpt	MFRP MAMDC4	4.38e-04	49	12	2	IPR002172
Domain	CUB_dom	MFRP MGAT3	5.92e-04	57	12	2	IPR000859
Pubmed	The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.	GIGYF2 EIF3A SRSF3	2.60e-06	74	13	3	35102251
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	GIGYF2 HCFC1 EIF3A SRSF3	6.10e-05	615	13	4	31048545
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	GIGYF2 HCFC1 EIF3A	1.21e-04	267	13	3	33417871
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	GIGYF2 EIF3A	1.21e-04	44	13	2	26471122
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	GIGYF2 EIF3A SRSF3	2.26e-04	330	13	3	32529326
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GIGYF2 HCFC1 EIF3A SRSF3	3.04e-04	934	13	4	33916271
Coexpression	BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN	NRTN HCFC1 MGAT3	6.10e-05	160	13	3	M9556
Computational	Neighborhood of TDG	EIF3A SRSF3	2.85e-04	35	8	2	GNF2_TDG
Computational	Neighborhood of DEK	EIF3A SRSF3	7.85e-04	58	8	2	GNF2_DEK
Disease	N-glycan measurement	NRTN MGAT3	2.91e-05	22	11	2	EFO_0004999
Disease	body surface area	GIGYF2 ZBTB4	2.29e-02	643	11	2	EFO_0022196

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAGGPERPSWPRRDH	MAMDC4	291	Q6UXC1
PGAVRRPPRGRGGWE	C19orf84	96	I3L1E1
RPPRGRGGWEVRHRP	C19orf84	101	I3L1E1
WAGRPPGPRRRAGPR	NRTN	76	Q99748
SVPAPWHGRRPRGLR	MFRP	46	Q9BY79
RVVGWSGPVPRPRHG	HCFC1	21	P51610
PSAPPARWGHGARRR	MAP3K10	656	Q02779
GGWRHRGPEGRPPAR	MGAT3	511	Q09327
KPRGRSLPRRRNPGW	C5orf60	251	A6NFR6
RRDGERWRPHSPDGP	GIGYF2	226	Q6Y7W6
RFPRRGDDSRPGPWR	EIF3A	1156	Q14152
ARVHGWLRRGPGGPP	CCDC166	266	P0CW27
RSRNRGPPPSWGRRP	SRSF3	86	P84103
GSGLPRGRRPPRWRQ	ZBTB4	686	Q9P1Z0
RPLQRRRPGTGPWRP	SCAND2P	226	Q9GZW5
RRPGTGPWRPGRQRG	SCAND2P	231	Q9GZW5