Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium- and calmodulin-responsive adenylate cyclase activity

ADCY3 ADCY5 ADCY6

1.75e-0552433GO:0008294
GeneOntologyBiologicalProcesscell junction organization

FRMPD4 NUMBL MYCBP2 CSMD2 NPHP4 F2RL1 GRHL2 PTK7 LRFN2 NF1 DLC1 HMCN2 PTPRF PIN1 TLN2 CLDN34 NPHS1 TMIGD1 FLNA IQSEC3 LRFN1 DLGAP4 DVL1 GRID1 IGSF11 IGF1R TIAM1 CNTNAP4 MDGA1 PHLDB2

2.13e-0697424730GO:0034330
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DCHS2 TRO CDH23 PTK7 HMCN2 PTPRF PKD1 EMB FAT3 IGSF11 CELSR1 HMCN1

2.79e-0618724712GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DCHS2 TRO CDH23 PTK7 HMCN2 PTPRF PKD1 EMB FAT3 IGSF11 CELSR1 HMCN1 MDGA1 CRB2

2.68e-0531324714GO:0098742
GeneOntologyBiologicalProcesssynapse organization

FRMPD4 NUMBL MYCBP2 CSMD2 PTK7 LRFN2 NF1 HMCN2 PTPRF PIN1 TLN2 FLNA IQSEC3 LRFN1 DLGAP4 DVL1 GRID1 IGSF11 IGF1R TIAM1 CNTNAP4 MDGA1

2.82e-0568524722GO:0050808
GeneOntologyCellularComponent9+2 non-motile cilium

CDH23 STRC STRCP1 TIAM1

1.85e-05142514GO:0097732
GeneOntologyCellularComponentkinocilium

CDH23 STRC STRCP1 TIAM1

1.85e-05142514GO:0060091
GeneOntologyCellularComponentstereocilium bundle

CDH23 ADGRV1 ADCY6 MYO3B STRC STRCP1 TIAM1

4.60e-05792517GO:0032421
GeneOntologyCellularComponentcluster of actin-based cell projections

CDH23 SLC46A1 ADGRV1 ADCY6 MYO3B STRC STRCP1 SLC6A18 FLNA CUBN TIAM1

8.50e-0522325111GO:0098862
GeneOntologyCellularComponentstereocilium tip

CDH23 MYO3B STRC STRCP1

1.25e-04222514GO:0032426
GeneOntologyCellularComponentstereocilium

CDH23 ADGRV1 ADCY6 MYO3B STRC STRCP1

1.80e-04692516GO:0032420
GeneOntologyCellularComponentpostsynaptic density

FRMPD4 RTN3 CSMD2 LRFN2 PTPRF MIB1 NR3C2 PLCB4 IQSEC3 LRFN1 DVL1 GRIA4 GRID1 IGSF11 TIAM1

3.88e-0445125115GO:0014069
GeneOntologyCellularComponentpostsynaptic specialization

FRMPD4 RTN3 CSMD2 LRFN2 PTPRF MIB1 NR3C2 PLCB4 IQSEC3 LRFN1 DLGAP4 DVL1 GRIA4 GRID1 IGSF11 TIAM1

4.08e-0450325116GO:0099572
GeneOntologyCellularComponentnon-motile cilium

ABCA4 CDH23 ADGRV1 NPHP4 MYO3B STRC STRCP1 TIAM1 CEP250

6.27e-041962519GO:0097730
GeneOntologyCellularComponentasymmetric synapse

FRMPD4 RTN3 CSMD2 LRFN2 PTPRF MIB1 NR3C2 PLCB4 IQSEC3 LRFN1 DVL1 GRIA4 GRID1 IGSF11 TIAM1

6.92e-0447725115GO:0032279
GeneOntologyCellularComponentcell-cell junction

DCHS2 KIRREL2 NPHP4 GRHL2 PTK7 TLN2 CLDN34 PDLIM2 NPHS1 TMIGD1 FLNA IGSF11 HMCN1 TIAM1 CGNL1 CRB2 PDZD2

8.39e-0459125117GO:0005911
GeneOntologyCellularComponentcentrosome

ACADS LRRC49 CCNO CDH23 STOX1 SFR1 NPHP4 ITGB6 MTUS1 MIB1 PLK1 NLRC3 DTL WRN ODF1 TIAM1 CEP250 CKAP2L ATM PDZD2

1.06e-0377025120GO:0005813
GeneOntologyCellularComponentcilium

ABCA4 CDH23 ADGRV1 PFKM NPHP4 ADCY3 ADCY5 ADCY6 PIN1 MYO3B PKD1 TEKT1 STRC STRCP1 TNPO1 ODF1 GPR88 DNAH1 TIAM1 CEP250 SPAG17 CFAP46

1.27e-0389825122GO:0005929
DomainIg_I-set

SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 LRFN1 EMB IGSF11 HMCN1 SIGLEC1 MDGA1

3.28e-0819024515IPR013098
DomainI-set

SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 LRFN1 EMB IGSF11 HMCN1 SIGLEC1 MDGA1

3.28e-0819024515PF07679
DomainEGF_CA

STAB1 HMCN2 UMODL1 FAT3 CUBN CELSR1 HMCN1 SUSD1 SLIT3 ADGRE1 CRB2

6.16e-0712224511SM00179
DomainEGF-like_Ca-bd_dom

STAB1 HMCN2 UMODL1 FAT3 CUBN CELSR1 HMCN1 SUSD1 SLIT3 ADGRE1 CRB2

7.26e-0712424511IPR001881
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN2 UMODL1 FAT3 CUBN CELSR1 HMCN1 SUSD1 SLIT3 ADGRE1 CRB2

1.33e-0610624510IPR000152
DomainIGc2

SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 LRFN1 IGSF11 HMCN1 SIGLEC1 MDGA1

2.86e-0623524514SM00408
DomainIg_sub2

SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 LRFN1 IGSF11 HMCN1 SIGLEC1 MDGA1

2.86e-0623524514IPR003598
DomainEGF_Ca-bd_CS

HMCN2 UMODL1 FAT3 CUBN HMCN1 SUSD1 SLIT3 ADGRE1 CRB2

5.20e-06972459IPR018097
DomainEGF_CA

HMCN2 UMODL1 FAT3 CUBN HMCN1 SUSD1 SLIT3 ADGRE1 CRB2

6.16e-06992459PS01187
DomainASX_HYDROXYL

HMCN2 UMODL1 FAT3 CUBN CELSR1 HMCN1 SUSD1 ADGRE1 CRB2

6.69e-061002459PS00010
DomainEGF_1

ITGB6 STAB1 HMCN2 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

7.35e-0625524514PS00022
DomainEGF-like_CS

ITGB6 STAB1 HMCN2 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

9.58e-0626124514IPR013032
DomainEGF_2

ITGB6 STAB1 HMCN2 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

1.14e-0526524514PS01186
DomainABC_A

ABCA1 ABCA4 ABCA13 ABCA12

1.32e-05122454IPR026082
DomainEGF_3

STAB1 HMCN2 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

1.44e-0523524513PS50026
DomainIg-like_fold

HLA-B MYCBP2 SPEG ISLR KIRREL2 PTK7 FNDC7 LRFN2 HMCN2 PTPRF UMODL1 NPHS1 TMIGD1 FLNA COL7A1 FLT3 LRFN1 EMB IGSF11 IGF1R HMCN1 KIR3DL3 SIGLEC1 MDGA1

2.07e-0570624524IPR013783
DomainEGF-like_dom

STAB1 HMCN2 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

2.65e-0524924513IPR000742
DomainL_dom-like

NLRP12 LRRC49 ISLR LRFN2 TONSL PKD1 NLRC3 NLRP5 LRFN1 SKP2 LRRC55 CMIP IGF1R LRRC25 SLIT3

3.03e-0532824515IPR032675
DomainGrowth_fac_rcpt_

STAB1 HMCN2 UMODL1 CUBN CELSR1 IGF1R HMCN1 SUSD1 SLIT3 ADGRE1

4.13e-0515624510IPR009030
DomainLeu-rich_rpt

NLRP12 LRRC49 ISLR LRFN2 TONSL PKD1 NLRC3 NLRP5 LRFN1 SKP2 LRRC55 LRRC25 SLIT3

6.35e-0527124513IPR001611
Domain-

HLA-B MYCBP2 SPEG ISLR KIRREL2 PTK7 FNDC7 LRFN2 PTPRF UMODL1 NPHS1 TMIGD1 FLNA COL7A1 FLT3 LRFN1 EMB IGSF11 IGF1R HMCN1 SIGLEC1 MDGA1

6.61e-05663245222.60.40.10
DomainEGF

STAB1 UMODL1 FAT3 ADAM32 CUBN CELSR1 HMCN1 SUSD1 SLIT3 CNTNAP4 ADGRE1 CRB2

6.71e-0523524512SM00181
DomainGPS

ADGRV1 PKD1 CELSR1 ADGRG2 ADGRE1

7.60e-05342455SM00303
DomainGPS

ADGRV1 PKD1 CELSR1 ADGRG2 ADGRE1

8.78e-05352455PF01825
DomainIG_LIKE

HLA-B SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 FLT3 LRFN1 EMB IGSF11 HMCN1 KIR3DL3 SIGLEC1 MDGA1

9.03e-0549124518PS50835
Domain-

NLRP12 LRRC49 ISLR LRFN2 TONSL PKD1 NLRC3 NLRP5 LRFN1 SKP2 LRRC55 CMIP LRRC25 SLIT3

9.27e-05321245143.80.10.10
DomainGPS

ADGRV1 PKD1 CELSR1 ADGRG2 ADGRE1

1.01e-04362455PS50221
DomainGPS

ADGRV1 PKD1 CELSR1 ADGRG2 ADGRE1

1.15e-04372455IPR000203
DomainAC_N

ADCY3 ADCY5 ADCY6

1.19e-0482453IPR032628
DomainAdcy

ADCY3 ADCY5 ADCY6

1.19e-0482453IPR030672
DomainAC_N

ADCY3 ADCY5 ADCY6

1.19e-0482453PF16214
DomainLAM_G_DOMAIN

FAT3 CELSR1 SLIT3 CNTNAP4 CRB2

1.31e-04382455PS50025
DomainEGF_CA

HMCN2 UMODL1 FAT3 CUBN HMCN1 SUSD1 ADGRE1

1.37e-04862457PF07645
DomainIG

SPEG KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 FLT3 LRFN1 EMB IGSF11 HMCN1 KIR3DL3 SIGLEC1 MDGA1

1.48e-0442124516SM00409
DomainIg_sub

SPEG KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 FLT3 LRFN1 EMB IGSF11 HMCN1 KIR3DL3 SIGLEC1 MDGA1

1.48e-0442124516IPR003599
DomainLaminin_G_2

FAT3 CELSR1 SLIT3 CNTNAP4 CRB2

1.69e-04402455PF02210
DomainFN3

SPEG FNDC7 LRFN2 PTPRF UMODL1 NPHS1 COL7A1 LRFN1 IGF1R MDGA1

1.71e-0418524510SM00060
DomainDVL-1

DVL1P1 DVL1

1.71e-0422452IPR008340
DomainLamG

FAT3 CELSR1 SLIT3 CNTNAP4 CRB2

2.67e-04442455SM00282
Domainfn3

SPEG FNDC7 LRFN2 PTPRF UMODL1 NPHS1 COL7A1 LRFN1 IGF1R

2.94e-041622459PF00041
DomainFN3

SPEG FNDC7 LRFN2 PTPRF UMODL1 NPHS1 COL7A1 LRFN1 IGF1R MDGA1

3.08e-0419924510PS50853
DomainGFP-like

STAB1 HMCN1 SUSD1

3.40e-04112453IPR023413
Domain-

STAB1 HMCN1 SUSD1

3.40e-041124532.40.155.10
DomainIg-like_dom

HLA-B SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF NPHS1 TMIGD1 FLT3 LRFN1 EMB IGSF11 HMCN1 SIGLEC1 MDGA1

3.66e-0450324517IPR007110
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

4.49e-04122453PF15371
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

4.49e-04122453IPR027970
DomainFN3_dom

SPEG FNDC7 LRFN2 PTPRF UMODL1 NPHS1 COL7A1 LRFN1 IGF1R MDGA1

4.54e-0420924510IPR003961
DomainATPase_dyneun-rel_AAA

VWA8 MDN1 DNAH1

7.29e-04142453IPR011704
DomainAAA_5

VWA8 MDN1 DNAH1

7.29e-04142453PF07728
DomainVWFA

VWA8 ITGB6 MDN1 HMCN2 COL7A1 HMCN1

7.30e-04822456PS50234
DomainVWA

VWA8 ITGB6 MDN1 HMCN2 COL7A1 HMCN1

8.30e-04842456SM00327
DomainLaminin_G

FAT3 CELSR1 SLIT3 CNTNAP4 CRB2

9.70e-04582455IPR001791
DomainPecanex_C

PCNX2 PCNX1

1.01e-0342452PF05041
DomainG2F

HMCN2 HMCN1

1.01e-0342452PF07474
DomainDishevelled

DVL1P1 DVL1

1.01e-0342452PF02377
DomainNIDOGEN_G2

HMCN2 HMCN1

1.01e-0342452PS50993
DomainGFP

HMCN2 HMCN1

1.01e-0342452IPR009017
DomainDishevelled_fam

DVL1P1 DVL1

1.01e-0342452IPR008339
DomainPecanex

PCNX2 PCNX1

1.01e-0342452IPR007735
DomainDishevelled_protein_dom

DVL1P1 DVL1

1.01e-0342452IPR003351
DomainG2_nidogen/fibulin_G2F

HMCN2 HMCN1

1.01e-0342452IPR006605
DomainCys-rich_flank_reg_C

ISLR LRFN2 PKD1 LRFN1 LRRC55 SLIT3

1.19e-03902456IPR000483
DomainLRRCT

ISLR LRFN2 PKD1 LRFN1 LRRC55 SLIT3

1.19e-03902456SM00082
DomainA/G_cyclase_CS

ADCY3 ADCY5 ADCY6

1.32e-03172453IPR018297
DomainEGF

STAB1 CUBN CELSR1 HMCN1 SLIT3 CNTNAP4 CRB2

1.38e-031262457PF00008
Domain-

ADCY3 ADCY5 ADCY6

1.57e-031824533.30.70.1230
DomainNucleotide_cyclase

ADCY3 ADCY5 ADCY6

1.57e-03182453IPR029787
Domain-

ADGRV1 FAT3 CELSR1 SLIT3 CNTNAP4 CRB2

1.57e-039524562.60.120.200
DomainGuanylate_cyc

ADCY3 ADCY5 ADCY6

1.85e-03192453PF00211
DomainGUANYLATE_CYCLASE_2

ADCY3 ADCY5 ADCY6

1.85e-03192453PS50125
DomainA/G_cyclase

ADCY3 ADCY5 ADCY6

1.85e-03192453IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY3 ADCY5 ADCY6

1.85e-03192453PS00452
DomainCYCc

ADCY3 ADCY5 ADCY6

1.85e-03192453SM00044
DomainVWF_A

VWA8 ITGB6 MDN1 HMCN2 COL7A1 HMCN1

1.94e-03992456IPR002035
DomainRCC1

MYCBP2 SERGEF HERC4

2.16e-03202453PF00415
DomainAdcy_conserved_dom

ADCY5 ADCY6

2.48e-0362452IPR009398
DomainDUF1053

ADCY5 ADCY6

2.48e-0362452PF06327
DomainRCC1_1

MYCBP2 SERGEF HERC4

2.49e-03212453PS00625
DomainRCC1_2

MYCBP2 SERGEF HERC4

2.49e-03212453PS00626
DomainRCC1_3

MYCBP2 SERGEF HERC4

2.49e-03212453PS50012
DomainPDZ

DVL1P1 FRMPD4 TIAM2 PDLIM2 DVL1 TIAM1 PDZD2

2.62e-031412457PF00595
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

RTN3 LRFN2 PTPRF LRFN1 GRIA4

4.03e-06201785MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

RTN3 LRFN2 PTPRF LRFN1 GRIA4

5.24e-06211785M27736
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

SPEG ISLR KIRREL2 PTK7 LRFN2 PTPRF FLT3 LRFN1 EMB IGSF11 HMCN1 SIGLEC1 MDGA1

2.33e-101622531325826454
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NUMBL MYCBP2 KIAA0232 MAP3K3 NF1 DLC1 MDN1 MTUS1 SEC16A RBM14 NR3C2 PLK1 DRG2 KIF26B DTL ARFGEF3 ZNF106 IGF1R RESF1 TIAM1 NCOA7 USP54 CGNL1 PHLDB2

2.41e-088612532436931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 SETD1B MYCBP2 VWA8 SPEG SREBF1 NPHP4 CASZ1 TIAM2 PCNX2 TNRC18 MDN1 PTPRF PKD1 SEC16A TLN2 DGCR2 FLNA LRFN1 DVL1 GRID1 FAAP100 CELSR1 IGF1R KANSL1 PCNX1 NUP188

4.67e-0811052532735748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1B FRMPD4 TRO KIAA0232 SPEG ADCY3 ADCY6 LRFN2 XPO5 SEC16A KATNIP IQSEC3 DLGAP4 ARFGEF3 KANSL1 PDZD2

6.16e-084072531612693553
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

CDH23 ADGRV1 ADCY3 ADCY5 ADCY6

8.01e-0816253517567809
Pubmed

Chromosomal mapping of human adenylyl cyclase genes type III, type V and type VI.

ADCY3 ADCY5 ADCY6

3.80e-07325338034296
Pubmed

RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1.

ADAR XPO5 TNPO1

3.80e-073253319124606
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 BRPF3 VWA8 ADGRV1 TIAM2 STAB1 MTUS1 SEMA5B MIB1 DGCR2 SLC7A6 FOXJ3 SLIT3 PCNX1 NUP188 EDEM1 HERC4

4.14e-075292531714621295
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CPAMD8 BRPF3 LRFN2 MTUS1 XPO5 GRID1 ARFGEF3 KANSL1

9.20e-07103253810574462
Pubmed

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.

ABCA1 SREBF1 NR1H3

1.51e-064253312897148
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

ISLR PTK7 LRFN2 SEMA5B LRFN1 SEMA5A CUBN MDGA1

2.42e-06117253817145500
Pubmed

Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury.

SREBF1 CCR2 ADGRE1

3.76e-065253318395093
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

CDH23 STRC STRCP1

3.76e-065253324920589
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ATRX MYCBP2 ADCY6 PRDM2 NF1 MDN1 SEC16A RBM14 TLN2 CLUH TLK2 FLNA STRN3 SEMA5A ZNF106 UTP18 KANSL1 ATM PHLDB2

4.67e-067742531915302935
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

FRMPD4 VWA8 KATNIP CLUH FOXJ3 RESF1 CNTNAP4 PDZD2

5.31e-06130253812421765
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 MYCBP2 KIAA0232 ADGRV1 ADCY6 STAB1 XPO5 SEC16A TLN2 PCNX1

6.62e-062252531012168954
Pubmed

Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.

ADCY3 ADCY5 ADCY6

7.49e-06625337766992
Pubmed

Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.

ADCY3 ADCY5 ADCY6

7.49e-066253311549699
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ATRX TRO CCNO STOX1 PFKM F2RL1 ADCY6 DNTTIP2 RYR2 PTK7 TNRC18 MDN1 UMODL1 ALAS2 PLIN1 ZNF541 FLNA STRN3 DTL GRIA4 UTP18 SUSD1 IRAK3 ATM POLQ SPAG17 CFAP46

7.64e-0614422532735575683
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MYCBP2 ADAR DNTTIP2 TNRC18 MDN1 SEC16A RBM14 WDR36 CCT7 UTP18 TRMT61A

9.99e-062892531123752268
Pubmed

Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.

ADCY3 ADCY5 ADCY6

1.30e-057253312613887
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

CDH23 ADGRV1 ADAR FLT3 DLGAP4 HMCN1 NUP188 CGNL1

1.67e-05152253834299191
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

KCNMB2 ABCA4 WDR64 CSMD2 TMEM200A CASZ1 RYR2 NF1 MDN1 MIB1 ZDBF2 FOXJ3 PIGT ADAMTS6 IRAK3 SOAT1

2.06e-056382531631182584
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

CDH23 STRC STRCP1

2.07e-058253321165971
Pubmed

Role of the calcium modulated cyclases in the development of the retinal projections.

ADCY3 ADCY5 ADCY6

3.09e-059253317229090
Pubmed

Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.

ADCY3 ADCY5 ADCY6

3.09e-059253312503609
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CPAMD8 ATRX NUMBL MYCBP2 KIAA0232 RTN3 ADGRV1 GRHL2 ADCY3 CASZ1 PTK7 PCNX2 TNRC18 LRFN2 KATNIP PLCB4 FOXJ3 DNAH1 ARFGEF3 CMIP IGF1R NACC2 MICAL2 GREB1 PDZD2 SOS2

3.71e-0514892532628611215
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

USP34 ACADS TRO KIAA0232 SLC46A1 ADCY6 NF1 MDN1 PTPRF XPO5 SEC16A LRFN1 SGCD DLGAP4 WDR83 SLC7A6 PIGT CMIP NUP188 ATM ALG13

3.73e-0510612532133845483
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ATRX NUMBL MYCBP2 CDH23 NPHP4 ADCY6 MAP3K3 NF1 XPO5 SEC16A RBM14 KATNIP PLK1 CLUH TNPO1 TLK2 LRFN1 WRN WDR83 FAAP100 PIGT TIAM1 SOAT1 PHLDB2

4.05e-0513212532427173435
Pubmed

Purification and characterization of a soluble form of mammalian adenylyl cyclase.

ADCY3 ADCY5 ADCY6

4.40e-051025338663304
Pubmed

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.

ADCY3 ADCY5 ADCY6

4.40e-0510253316615126
Pubmed

Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development.

IGF1R ADGRE1 EMCN

4.40e-0510253335388142
Pubmed

Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.

ADCY3 ADCY5 ADCY6

4.40e-0510253311884542
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 ATRX ADCY3 SDR39U1 DNTTIP2 TIAM2 PRDM2 MAP3K3 SEC16A TNPO1 TLK2 NRDE2 FLNA DTL CUBN FOXJ3 ZSCAN10 RESF1 NUP188 HERC4 TRIM37

5.07e-0510842532111544199
Pubmed

Adenylyl cyclase 6 deficiency ameliorates polycystic kidney disease.

ADCY6 PKD1

5.27e-052253224158982
Pubmed

Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation.

HLA-B EDEM1

5.27e-052253225132672
Pubmed

DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.

FLT3 POLQ

5.27e-052253236580665
Pubmed

Homocysteine-mediated cholesterol efflux via ABCA1 and ACAT1 DNA methylation in THP-1 monocyte-derived foam cells.

ABCA1 SOAT1

5.27e-052253223305686
Pubmed

No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model.

ABCA1 TIAM1

5.27e-052253216192287
Pubmed

Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes.

KIRREL2 NPHS1

5.27e-052253224219158
Pubmed

Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β1-adrenoceptor-mediated inotropic response.

ADCY5 ADCY6

5.27e-052253231009605
Pubmed

The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.

ATM POLQ

5.27e-052253215542845
Pubmed

WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.

WRN ATM

5.27e-052253218596239
Pubmed

The Filamin-A is a partner of Tc-mip, a new adapter protein involved in c-maf-dependent Th2 signaling pathway.

FLNA CMIP

5.27e-052253215128042
Pubmed

Association between LXR-α and ABCA1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus in a Chinese Han Population.

ABCA1 NR1H3

5.27e-052253233426085
Pubmed

Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.

ATRX ATM

5.27e-052253229378238
Pubmed

Genetic variations in SREBP-1 and LXRα are not directly associated to PCOS but contribute to the physiological specifics of the syndrome.

SREBF1 NR1H3

5.27e-052253222311022
Pubmed

Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.

SPEG RYR2

5.27e-052253232683896
Pubmed

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia.

ADCY5 ADCY6

5.27e-052253231162142
Pubmed

Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology.

TIAM2 TIAM1

5.27e-052253214550769
Pubmed

Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.

ADCY5 ADCY6

5.27e-052253220431059
Pubmed

Genes of cholesterol metabolism in human atheroma: overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression.

ABCA1 PLIN1

5.27e-052253215961705
Pubmed

Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.

SREBF1 PLIN1

5.27e-052253223734208
Pubmed

Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2.

OR1A2 OR1A1

5.27e-052253217601748
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

5.27e-05225328644734
Pubmed

Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2.

TIAM2 TIAM1

5.27e-052253218997336
Pubmed

Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23ahl.

CDH23 EMB

5.27e-052253237854703
Pubmed

Pecanex functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer.

SKP2 PCNX1

5.27e-052253228789966
Pubmed

NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.

NF1 ATM

5.27e-052253231664505
Pubmed

Filamin a binds to CCR2B and regulates its internalization.

CCR2 FLNA

5.27e-052253220808917
Pubmed

Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

ABCA1 NR1H3

5.27e-052253212105210
Pubmed

The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.

PIN1 IRAK3

5.27e-052253229686383
Pubmed

AMPK activates LXRα and ABCA1 expression in human macrophages.

ABCA1 NR1H3

5.27e-052253227343431
Pubmed

Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytes.

ADCY5 ADCY6

5.27e-052253223609114
Pubmed

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

ADCY5 ADCY6

5.27e-052253219734365
Pubmed

Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease.

SREBF1 NR1H3

5.27e-052253219360318
Pubmed

Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice.

USP34 ATM

5.27e-052253237043976
Pubmed

Decreased mRNA expression of NR1H3 and ABCA1 in pulmonary tuberculosis patients from population of Punjab, India.

ABCA1 NR1H3

5.27e-052253238740636
Pubmed

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.

ABCA1 NR1H3

5.27e-052253226173179
Pubmed

LXR driven induction of HDL-cholesterol is independent of intestinal cholesterol absorption and ABCA1 protein expression.

ABCA1 NR1H3

5.27e-052253224163219
Pubmed

The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy.

SREBF1 NR1H3

5.27e-052253232144382
Pubmed

On the regulatory importance of 27-hydroxycholesterol in mouse liver.

SREBF1 NR1H3

5.27e-052253226851362
Pubmed

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.

ABCA1 ADGRE1

5.27e-052253210878804
Pubmed

CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01.

CCR2 FLT3

5.27e-052253233519816
Pubmed

Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines.

SREBF1 NR1H3

5.27e-052253222415588
Pubmed

A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1.

ADAR TNPO1

5.27e-052253224753571
Pubmed

The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.

CDH23 ADGRV1

5.27e-052253215820310
Pubmed

Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression.

ABCA1 NR1H3

5.27e-052253226452260
Pubmed

Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis.

SREBF1 NR1H3

5.27e-052253220005944
Pubmed

Lipoxin A4 promotes ABCA1 expression and cholesterol efflux through the LXRα signaling pathway in THP-1 macrophage-derived foam cells.

ABCA1 NR1H3

5.27e-052253226261553
Pubmed

Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 model.

ADCY6 PKD1

5.27e-052253224994926
Pubmed

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.

SREBF1 NR1H3

5.27e-052253216054077
Pubmed

Expression of multiple adenylyl cyclase isoforms in human and dog thyroid.

ADCY3 ADCY6

5.27e-052253211162902
Pubmed

Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development.

PIN1 PKD1

5.27e-052253219367327
Pubmed

The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6.

ADCY5 ADCY6

5.27e-052253217068292
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

5.27e-052253234910522
Pubmed

Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1.

IGF1R ATM

5.27e-052253215345673
Pubmed

Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.

PKD1 ATM

5.27e-052253233802342
Pubmed

Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells.

ADCY3 ADCY6

5.27e-052253222952279
Pubmed

Oleic acid modulates mRNA expression of liver X receptor (LXR) and its target genes ABCA1 and SREBP1c in human neutrophils.

ABCA1 SREBF1

5.27e-052253224722912
Pubmed

Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.

PLK1 ATM

5.27e-052253217121863
Pubmed

Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure.

ADCY3 ADCY6

5.27e-052253224431204
Pubmed

IRAK-M Regulates Monocyte Trafficking to the Lungs in Response to Bleomycin Challenge.

CCR2 IRAK3

5.27e-052253232253243
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

5.27e-052253211687802
Pubmed

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.

SREBF1 SOAT1

5.27e-052253227281560
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

5.27e-052253232035013
Pubmed

Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages.

ABCA1 NR1H3

5.27e-052253220506155
Pubmed

Inhibition of Plk1 and Pin1 by 5'-nitro-indirubinoxime suppresses human lung cancer cells.

PIN1 PLK1

5.27e-052253222115795
Pubmed

STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/β-catenin signaling pathway.

SREBF1 STAMBPL1

5.27e-052253239150093
Pubmed

Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.

TIAM2 TIAM1

5.27e-052253211707441
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SPEG ISLR KIRREL2 PTK7 LRFN2 HMCN2 PTPRF TMIGD1 LRFN1 EMB IGSF11 HMCN1 SIGLEC1 MDGA1

5.10e-1016117414593
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA4 ABCA13 ABCA12

7.69e-06141744805
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY3 ADCY5 ADCY6

1.00e-0410174353
GeneFamilyCadherin related

DCHS2 CDH23 FAT3

5.39e-0417174324
GeneFamilyImmunoglobulin like domain containing

KIRREL2 PTK7 HMCN2 NPHS1 TMIGD1 FLT3 EMB MDGA1

5.71e-041931748594
GeneFamilyFibronectin type III domain containing

FNDC7 LRFN2 PTPRF NPHS1 COL7A1 LRFN1 IGF1R

9.20e-041601747555
GeneFamilyWD repeat domain containing|UTPB complex

WDR36 UTP18

1.35e-03617421225
GeneFamilyNLR family

NLRP12 NLRC3 NLRP5

1.72e-03251743666
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB1 CD163L1 CD68

2.16e-032717431253
GeneFamilyFibulins

HMCN2 HMCN1

2.48e-0381742556
GeneFamilyPDZ domain containing

FRMPD4 TIAM2 PDLIM2 DVL1 TIAM1 PDZD2

3.55e-0315217461220
CoexpressionGSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP

CCR2 NF1 TTC7B PLK1 CAMP DTL CELSR1 ELL2 CD68 EDEM1 ADGRE1

1.09e-0617625011M8881
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 FRMPD4 ABCA13 ABCA12 ADGRV1 RYR2 PIK3C2G TLN2 MGAM KIF26B FAT3 GRID1 DNAH1 ARFGEF3 HMCN1 CNTNAP4 SPAG17

5.54e-16184252172cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 FRMPD4 ABCA13 ABCA12 ADGRV1 RYR2 PIK3C2G TLN2 MGAM KIF26B FAT3 GRID1 DNAH1 ARFGEF3 HMCN1 CNTNAP4 SPAG17

5.54e-16184252172b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 FRMPD4 ABCA13 ABCA12 ADGRV1 RYR2 PIK3C2G TLN2 MGAM KIF26B FAT3 GRID1 DNAH1 ARFGEF3 HMCN1 CNTNAP4 SPAG17

5.54e-1618425217ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 PTPRF MTUS1 LIPH NR3C2 ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

5.61e-1219225214499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ABCA12 ADGRV1 RYR2 PIK3C2G MYO3B ALAS2 FAT3 CAMP GRIA4 CUBN KCNH4 DNAH1

1.66e-111692521312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ADGRV1 GRHL2 ITGB6 CASZ1 PTPRF MTUS1 LIPH ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

6.33e-1118825213c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 PTPRF MTUS1 LIPH ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

8.23e-1119225213efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRV1 GRHL2 ITGB6 DLC1 PTPRF MTUS1 LIPH ARFGEF3 MICAL2 NCOA7 USP54 CGNL1 PDZD2

9.99e-11195252139406866f99555198a9be311fbd65751b70f35446
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 LIPH ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

1.05e-0919125212e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 WDR64 ABCA12 ADGRV1 RYR2 PIK3C2G KLF18 FAT3 GRIA4 HMCN1 CNTNAP4

2.04e-0916025211c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NLRP12 MGAM LRFN1 TCN1 EMB CAMP CUBN ZNF792 SLIT3 IRAK3 ADGRE1

2.04e-091602521176f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 WDR64 ABCA12 ADGRV1 RYR2 PIK3C2G KLF18 FAT3 GRIA4 HMCN1 CNTNAP4

2.04e-091602521125c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NLRP12 MGAM LRFN1 TCN1 EMB CAMP CUBN ZNF792 SLIT3 IRAK3 ADGRE1

2.04e-0916025211bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK7 DLC1 SEMA5B PLCB4 EMB SEMA5A CELSR1 SLIT3 CNTNAP4 CGNL1 PHLDB2

7.87e-091822521172e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK7 DLC1 SEMA5B PLCB4 EMB SEMA5A CELSR1 SLIT3 CNTNAP4 CGNL1 PHLDB2

7.87e-091822521105c167158815bf25d509df59ab386e1990712765
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 GRHL2 ITGB6 PTPRF MTUS1 LIPH NR3C2 ARFGEF3 CELSR1 USP54

1.45e-0819325211a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRV1 GRHL2 ITGB6 MTUS1 LIPH ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

1.99e-08199252115f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRV1 GRHL2 ITGB6 MTUS1 LIPH ARFGEF3 CELSR1 MICAL2 USP54 CGNL1 PDZD2

1.99e-08199252115cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRHL2 CASZ1 LIPH PLCB4 TCN1 SLC26A5 ARFGEF3 CELSR1 SLIT3 BPIFB2 CGNL1

2.09e-0820025211c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

ADGRV1 GRHL2 ITGB6 CASZ1 PTPRF LIPH MICAL2 USP54 CGNL1 PDZD2

8.00e-0817925210a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APCDD1 ISLR PTK7 MFAP4 COL7A1 KIF26B SGCD CAMK2N2 HMCN1 PCOLCE

8.43e-0818025210935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APCDD1 ISLR PTK7 MFAP4 COL7A1 KIF26B SGCD CAMK2N2 HMCN1 PCOLCE

8.43e-08180252103dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK7 DLC1 PIK3C2G PLCB4 EMB SEMA5A CELSR1 SLIT3 CNTNAP4 CGNL1

8.43e-0818025210e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APCDD1 ISLR PTK7 MFAP4 COL7A1 KIF26B SGCD CAMK2N2 HMCN1 PCOLCE

9.84e-0818325210803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APCDD1 ISLR PTK7 MFAP4 COL7A1 KIF26B SGCD CAMK2N2 HMCN1 PCOLCE

9.84e-08183252106d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APCDD1 ISLR PTK7 MFAP4 COL7A1 KIF26B SGCD CAMK2N2 HMCN1 PCOLCE

9.84e-0818325210cc7f5a17b40e8d901885174922e5fa8877643071
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY3 DLC1 PLCB4 FLNA SEMA5A GRID1 MICAL2 SLIT3

9.84e-0818325210667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRHL2 ITGB6 PTPRF MTUS1 SCNN1G SLC26A5 CELSR1 USP54 CGNL1 PHLDB2

1.04e-071842521042ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 GRHL2 ITGB6 MTUS1 LIPH NR3C2 ARFGEF3 CELSR1 USP54

1.15e-07186252102ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRHL2 ITGB6 PTPRF MTUS1 SCNN1G SLC26A5 CELSR1 USP54 CGNL1 PHLDB2

1.15e-07186252104e94158db52df41d71e67b02b9895a358eebee0f
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 GRHL2 PTPRF MTUS1 PIK3C2G MYO3B TMEM59L NR3C2 ADAMTS6 MICAL2

1.20e-0718725210db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRV1 GRHL2 ITGB6 PTPRF MTUS1 SLC26A5 CELSR1 USP54 CGNL1 PHLDB2

1.20e-071872521058d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY5 RYR2 DLC1 ALPP FLNA GRID1 MICAL2 SLIT3

1.33e-0718925210127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY5 RYR2 DLC1 ALPP FLNA GRID1 MICAL2 SLIT3

1.33e-07189252102cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 PIK3C2G NR3C2 ELL2 USP54

1.47e-071912521034cc997e4e5c727495f321e6807a84aa124da486
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 LIPH NR3C2 USP54 CGNL1

1.47e-0719125210d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

ADGRV1 GRHL2 PTPRF MTUS1 LIPH TEKT1 ARFGEF3 USP54 SPAG17 CFAP46

1.54e-07192252100644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RYR2 PTK7 MFAP4 KIF26B SGCD FAT3 SEMA5A GRID1 SLIT3 PCOLCE

1.54e-0719225210deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 RTN3 GRHL2 ITGB6 PTPRF PIK3C2G MYO3B NR3C2 MGAM SUSD1

1.70e-071942521004bfc555743f7d8821439d05ae442d15e9886c59
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRV1 ITGB6 DLC1 MTUS1 ARFGEF3 MICAL2 NCOA7 USP54 CGNL1 PDZD2

1.70e-071942521053f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

KCNMB2 GRHL2 PTPRF LIPH TEKT1 ARFGEF3 CELSR1 USP54 SPAG17 CFAP46

1.87e-071962521087d9881cfec461a5d89b688a83749b618c519485
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG ADCY5 RYR2 HMCN2 PLCB4 STAMBPL1 FLNA SGCD FAT3 SLIT3

1.96e-0719725210bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

GLDN CDH23 TMEM200A RYR2 MFAP4 KIF26B FAT3 HMCN1 SLIT3 PCOLCE

2.05e-07198252103ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 LIPH MICAL2 USP54 CGNL1 PDZD2

2.15e-07199252108587bd98de7767a575088afbea07a1feb4516b9b
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 ATRX MYCBP2 ADAR PRDM2 TLK2 RESF1 KANSL1 SIGLEC1 ATM

2.25e-072002521012f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG ADCY5 RYR2 HMCN2 PLCB4 STAMBPL1 FLNA SGCD FAT3 SLIT3

2.25e-0720025210a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

DCHS2 NLRP12 ADCY5 COL7A1 CAMK2N2 LRRC55 HMCN1 SLIT3 CGNL1

3.22e-0715925294f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 NXPE2 F2RL1 SLC25A43 CD163L1 ALAS2 TG ELL2 EDEM1

4.40e-071652529361a605d8f833d9ec54b120480dce397da35f9c3
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA8 LRRC49 CCR2 SLC25A43 TLK2 FLT3 ZNF106 ADGRE1 SOAT1

4.63e-0716625295c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ABCA1 ADGRV1 DLC1 SEMA5A SLCO2A1 NCOA7 USP54 PHLDB2 PDZD2

5.66e-071702529e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCHS2 ADCY3 ADCY5 RYR2 PLCB4 FAT3 GRIA4 SLIT3 PCOLCE

5.66e-0717025295570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 SCNN1G EMB CAMP HMCN1 CGNL1 TRIM37 PHLDB2 EMCN

6.88e-07174252942dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 SCNN1G EMB CAMP HMCN1 CGNL1 TRIM37 PHLDB2 EMCN

6.88e-071742529f04edf2ca6788875c9918611e416fb739924382e
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG NPHP4 TONSL PCYOX1 DTL ACVR1C KCNH4 CKAP2L CLSPN

8.32e-071782529de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA4 GRHL2 ITGB6 PTPRF SCNN1G SLC26A5 CELSR1 CGNL1 PHLDB2

8.72e-07179252904ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SPEG ADCY5 RYR2 TLN2 STAMBPL1 FLNA SGCD FAT3 SLIT3

9.13e-071802529d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRHL2 ITGB6 PTPRF SCNN1G SLC26A5 SEMA5A CELSR1 CGNL1 PHLDB2

9.56e-071812529b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

SPEG ADCY5 DLC1 HMCN2 PLCB4 STAMBPL1 FLNA FAT3 SLIT3

1.05e-061832529818fd886e0188091310825f9145fa53328f2c979
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRHL2 ITGB6 PTPRF SCNN1G SLC26A5 CELSR1 USP54 CGNL1 PHLDB2

1.15e-061852529c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

ADCY6 PTK7 TNRC18 TLN2 PLCB4 KIF26B CMIP KANSL1 GREB1

1.20e-061862529de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRHL2 ITGB6 PTPRF SCNN1G SLC26A5 CELSR1 USP54 CGNL1 PHLDB2

1.20e-0618625293aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADCY6 PTK7 TNRC18 TLN2 PLCB4 KIF26B CMIP KANSL1 GREB1

1.20e-0618625290b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 GRHL2 ITGB6 MTUS1 LIPH ARFGEF3 CELSR1 USP54

1.25e-06187252981cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

SPEG ADCY5 RYR2 PLCB4 STAMBPL1 KIF26B SEMA5A SLIT3 PHLDB2

1.25e-061872529464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ADCY3 RYR2 DLC1 PLCB4 FLNA GRID1 MICAL2 SLIT3

1.31e-061882529b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 ITGB6 DLC1 SCNN1G PCYOX1 SERTM1 SEMA5A NCOA7 PHLDB2

1.31e-061882529e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 ARFGEF3 MICAL2 USP54 PDZD2

1.31e-061882529707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

HLA-B PTPN12 DLC1 CMIP HMCN1 SLCO2A1 IRAK3 CGNL1 EMCN

1.37e-061892529c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY3 ADCY5 RYR2 DLC1 FLNA MICAL2 SLIT3

1.37e-0618925297fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY3 ADCY5 RYR2 DLC1 FLNA MICAL2 SLIT3

1.37e-06189252906b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 NR3C2 ARFGEF3 CGNL1 PDZD2

1.49e-061912529a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

GLDN ACP5 STAB1 CD163L1 TG TIAM1 CD68 IRAK3 SIGLEC1

1.49e-0619125299c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ADCY5 RYR2 MFAP4 SGCD FAT3 GRID1 SLIT3 PCOLCE

1.49e-06191252914057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ADCY3 ADCY5 RYR2 DLC1 FLNA GRID1 MICAL2 SLIT3

1.49e-06191252904c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

GLDN ACP5 SPOCD1 IQSEC3 NR1H3 TIAM1 IRAK3 SIGLEC1 SOAT1

1.49e-061912529dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ITGB6 DLC1 MTUS1 LIPH NR3C2 ARFGEF3 MICAL2 USP54 CGNL1

1.56e-0619225291bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellmild-Myeloid-Immature_Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GLDN ABCA13 PLK1 TCN1 CAMP DTL CKAP2L CLSPN POLQ

1.56e-0619225290445fdc670fa7b847dcd0a061d7736ddcf3519ba
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

GLDN ACP5 SPOCD1 IQSEC3 NR1H3 TIAM1 IRAK3 SIGLEC1 SOAT1

1.56e-061922529bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ISLR CSMD2 PTK7 TLN2 COL7A1 KIF26B SGCD HMCN1 PCOLCE

1.56e-06192252967e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 NR3C2 ARFGEF3 MICAL2 PDZD2

1.56e-06192252958c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

CCNO ADGRV1 GRHL2 PTPRF LIPH SCNN1G TCN1 ARFGEF3 CELSR1

1.56e-06192252959261098ccb52306f837f632ebaea45b90ad30fe
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRV1 GRHL2 ITGB6 DLC1 MTUS1 PIK3C2G NR3C2 MICAL2 PDZD2

1.56e-061922529fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

CPAMD8 CCNO ADGRV1 MTUS1 LIPH SCNN1G ARFGEF3 CELSR1 USP54

1.63e-0619325292bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 ACP5 FLNA CAMP NR1H3 SUSD1 CD68 SIGLEC1 ADGRE1

1.63e-06193252950c2832de75b6469f649355c6b9a75e910d32db3
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CCNO ADGRV1 GRHL2 LIPH MYO3B TMEM59L SCNN1G ARFGEF3 CELSR1

1.63e-061932529b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 ACP5 FLNA CAMP NR1H3 SUSD1 CD68 SIGLEC1 ADGRE1

1.63e-061932529222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 CASZ1 DLC1 MTUS1 NR3C2 ARFGEF3 MICAL2 USP54 PDZD2

1.70e-06194252997534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLDN SPEG ADCY3 ADCY5 DLC1 FLNA GRID1 MICAL2 SLIT3

1.70e-061942529ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

KCNMB2 GRHL2 LIPH TEKT1 PLCB4 ARFGEF3 USP54 SPAG17 CFAP46

1.77e-061952529fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

KCNMB2 GRHL2 LIPH TEKT1 PLCB4 ARFGEF3 USP54 SPAG17 CFAP46

1.77e-061952529eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

ADGRV1 GRHL2 ITGB6 PTPRF MTUS1 LIPH ARFGEF3 USP54 CGNL1

1.77e-0619525291798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG RYR2 DLC1 HMCN2 FLNA SGCD FAT3 MICAL2 SLIT3

1.85e-0619625291522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ISLR ADCY5 TMEM200A RYR2 MFAP4 HMCN2 TMEM59L TLN2 SEMA5A

1.85e-061962529614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG RYR2 DLC1 HMCN2 FLNA SGCD FAT3 MICAL2 SLIT3

1.85e-0619625291c8294014713684b50885e638668f2ce75f357f0
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 EMB KIF26B CELSR1 HMCN1 MICAL2 SLCO2A1 CGNL1 EMCN

1.85e-061962529dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell10x_3'_v3-blood_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NLRP12 RTN3 ALAS2 MGAM FLT3 LRRC25 NACC2 MICAL2 IRAK3

1.93e-0619725292d3547107c88c7443fc6425742694e13368a71f5
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

ITGB6 DLC1 SCNN1G PCYOX1 ALPP SERTM1 SEMA5A CGNL1 PHLDB2

2.01e-06198252975bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GLDN SPEG ADCY3 ADCY5 RYR2 DLC1 FLNA GRID1 PHLDB2

2.01e-0619825297dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCNO ADGRV1 GRHL2 MTUS1 LIPH SCNN1G ARFGEF3 CELSR1 USP54

2.01e-0619825295fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCNO ADGRV1 GRHL2 MTUS1 LIPH SCNN1G ARFGEF3 CELSR1 USP54

2.01e-0619825296ba5e5970109a04ed968bac7ff099ae250c579dc
Diseasecortical thickness

CPAMD8 ABCA4 HLA-B MYCBP2 LRRC49 SREBF1 ADGRV1 STOX1 STAB1 DLC1 PTPRF XPO5 UMODL1 PKD1 CLUH STRN3 FAT3 TG ZNF106 CELSR1 IGF1R KANSL1 CD68 SOAT1 CRB2 PDZD2 SOS2

6.44e-07111324427EFO_0004840
DiseaseColorectal Carcinoma

CPAMD8 ABCA1 ABCA4 ABCA13 ABCA12 ISLR NF1 DLC1 SCNN1G NR3C2 COL7A1 WRN GRID1 CUBN KCNH4 TIAM1 SLCO2A1 BPIFB2 SPAG17

7.00e-0670224419C0009402
Diseasebrain disease (implicated_via_orthology)

MYCBP2 TIAM2 TIAM1

1.10e-0562443DOID:936 (implicated_via_orthology)
Diseasecortical surface area measurement

USP34 DCHS2 CPAMD8 HLA-B APCDD1 MYCBP2 SREBF1 ADGRV1 STOX1 PTPRF PKD1 TLN2 NR3C2 STRN3 KIF26B FAT3 SEMA5A TG ZNF106 CELSR1 KANSL1 SPAG17 SOAT1 TRMT61A PDZD2 SOS2

5.59e-05134524426EFO_0010736
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

6.81e-0522442DOID:0110471 (implicated_via_orthology)
Diseasemicrofibril-associated glycoprotein 4 measurement

STAB1 MFAP4

6.81e-0522442EFO_0802744
Diseasecataract 48 (implicated_via_orthology)

TIAM2 TIAM1

6.81e-0522442DOID:0070354 (implicated_via_orthology)
DiseaseGlioma

IL12A HLA-B ATRX NF1 PLK1 ATM

8.68e-05872446C0017638
Diseaseprotocadherin alpha-4 measurement

ODF1 SIGLEC1

2.03e-0432442EFO_0801972
Diseaseglucose-6-phosphate isomerase measurement

NLRP12 CD163L1

2.03e-0432442EFO_0020407
DiseaseMalignant Glioma

IL12A HLA-B ATRX NF1 PLK1

2.90e-04702445C0555198
Diseasemixed gliomas

IL12A HLA-B ATRX NF1 PLK1

2.90e-04702445C0259783
Diseasecopine-1 measurement

NLRP12 DLGAP4 CEP250

3.49e-04172443EFO_0008102
Diseaseurate measurement

USP34 ABCA1 ISLR ADGRV1 ITGB6 STAB1 PTPRF LIPH MYO3B COL7A1 ODF1 CUBN DNAH1 CMIP IGF1R NCOA7 HERC4 SOS2

5.09e-0489524418EFO_0004531
DiseaseColorectal Neoplasms

CPAMD8 ABCA1 ABCA4 ABCA13 ABCA12 DLC1 COL7A1 GRID1 SLCO2A1

5.33e-042772449C0009404
DiseaseNonsyndromic Deafness

CDH23 ADGRV1 GRHL2 STRC SLC26A5

5.70e-04812445C3711374
Diseasewaist-hip ratio

CPAMD8 ABCA1 APCDD1 MYCBP2 F2RL1 ADCY3 ADCY5 MAP3K3 PTK7 STAB1 LRFN2 DLC1 MYO3B PKD1 SGCD ACVR1C CMIP UTP18 IGF1R ADAMTS6 PCNX1 PHLDB2

5.83e-04122624422EFO_0004343
Diseaseneuroimaging measurement, brain volume measurement

USP34 NF1 EEF1AKMT4-ECE2 STRN3 KIF26B FAT3 KANSL1 NCOA7 CRB2

6.69e-042862449EFO_0004346, EFO_0006930
DiseaseAnemia, Megaloblastic

TCN1 CUBN

6.70e-0452442C0002888
Diseasejuvenile myelomonocytic leukemia (implicated_via_orthology)

NF1 FLT3

6.70e-0452442DOID:0050458 (implicated_via_orthology)
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

6.70e-0452442DOID:11198 (is_implicated_in)
Diseaseblood rubidium measurement

ABCA13 SGCD MDGA1

1.26e-03262443EFO_0021529
Diseaseflavin adenine dinucleotide (FAD) measurement

HLA-B PCYOX1

1.39e-0372442EFO_0800177
Diseaselethal congenital contracture syndrome (is_implicated_in)

GLDN ADCY6

1.39e-0372442DOID:0060558 (is_implicated_in)
DiseaseHypotrichosis simplex

APCDD1 LIPH

1.39e-0372442C1854310
Diseaselung small cell carcinoma (is_implicated_in)

ATRX XPO5 ATM

1.57e-03282443DOID:5409 (is_implicated_in)
Diseasediffuse plaque measurement

SLC17A2 DCHS2 VWA8 ABCA13 DLC1 MYO3B TEKT1 KIF26B GRID1 ZDBF2 ARFGEF3 CMIP SLCO2A1 ADGRE1 EMCN

1.73e-0375824415EFO_0010699
Diseasesuicidal ideation

CDH23 WDR36 CFAP46

1.74e-03292443EFO_0004320
Diseasebipolar II disorder

SLIT3 ADGRE1

1.85e-0382442EFO_0009964
Diseasepremature menopause (biomarker_via_orthology)

ABCA1 NR1H3

1.85e-0382442DOID:10787 (biomarker_via_orthology)
Diseasediastolic blood pressure, self reported educational attainment

PIK3C2G SLIT3

1.85e-0382442EFO_0004784, EFO_0006336
Diseasepseudohypoaldosteronism (is_implicated_in)

SCNN1G NR3C2

1.85e-0382442DOID:4479 (is_implicated_in)
DiseaseVentricular Dysfunction, Left

ADCY5 NR3C2 ATM

1.92e-03302443C0242698
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

XPO5 NPHS1 CRB2

1.92e-03302443C1868672
Diseasesexual dimorphism measurement

BRPF3 ABCA1 ISLR ADCY3 MAP3K3 NF1 PKD1 SEC16A SPOCD1 SLC22A20P TMIGD1 MGAM COL7A1 DLGAP4 CMIP IGF1R CEP250 SLIT3 PARN

2.25e-03110624419EFO_0021796
DiseaseSquamous cell carcinoma of lung

PLK1 ACVR1C IGF1R

2.32e-03322443C0149782
Diseasehealth-related quality of life measurement

SGCD SEMA5A

2.36e-0392442EFO_0011014
Diseasemitral valve prolapse (is_implicated_in)

HLA-B FLNA

2.36e-0392442DOID:988 (is_implicated_in)
Diseaseimmunoglobulin M measurement

ODF1 SIGLEC1

2.36e-0392442EFO_0020466
Diseaseendometrial carcinoma

CSMD2 NF1 DLC1 MDN1 KIF26B

2.52e-031132445EFO_1001512
Diseasesusceptibility to mononucleosis measurement

RYR2 MDN1 WDR36 CMIP

2.59e-03692444EFO_0008403
Diseasereticulocyte count

USP34 ABCA1 ACADS VWA8 PFKM F2RL1 ADCY3 PKD1 TLN2 SPOCD1 EEF1AKMT4-ECE2 ACVR1C KANSL1 SUSD1 ZNF792 MICAL2 NCOA7 PDZD2

2.84e-03104524418EFO_0007986
DiseaseHyperpotassemia and Hypertension, Familial

SCNN1G NR3C2

2.93e-03102442C2713447
DiseasePseudohypoaldosteronism, Type I, Autosomal Recessive

SCNN1G NR3C2

2.93e-03102442C1449843
DiseasePseudohypoaldosteronism, Type II

SCNN1G NR3C2

2.93e-03102442C1449844
DiseasePseudohypoaldosteronism, Type I, Autosomal Dominant

SCNN1G NR3C2

2.93e-03102442C1449842
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

SLC46A1 TG

2.93e-03102442EFO_0008321
DiseasePseudohypoaldosteronism, Type I

SCNN1G NR3C2

2.93e-03102442C0268436
Diseasemyelodysplastic syndrome

HLA-B GRID1

2.93e-03102442EFO_0000198
DiseasePseudohypoaldosteronism

SCNN1G NR3C2

2.93e-03102442C0033805
Diseasecognitive function measurement, self reported educational attainment

GLDN HLA-B MYCBP2 STAB1 PTPRF WRN KANSL1 CNTNAP4 TRIM37

2.95e-033552449EFO_0004784, EFO_0008354
Diseasecoronary aneurysm

CSMD2 MYO3B MDGA1

3.01e-03352443EFO_1000881
DiseaseAutoinflammatory disorder

NLRP12 ACP5 ADAR

3.01e-03352443C3860213
Diseasereticulocyte measurement

USP34 ABCA1 ACADS VWA8 PFKM ADCY3 TLN2 SPOCD1 FLNA ACVR1C KANSL1 SUSD1 ZNF792 MICAL2 NCOA7 SIGLEC1 SOAT1 PDZD2

3.08e-03105324418EFO_0010700
DiseaseLiver carcinoma

SREBF1 MTUS1 TONSL PLK1 NLRC3 DTL SKP2 IGF1R CNTNAP4 CKAP2L ATM

3.52e-0350724411C2239176
Diseasesleep disorder (implicated_via_orthology)

NF1 IGF1R

3.57e-03112442DOID:535 (implicated_via_orthology)
Diseasesenile cataract (is_implicated_in)

WRN ATM

3.57e-03112442DOID:9669 (is_implicated_in)
DiseaseHyperhomocysteinemia

SLC46A1 NPHS1

3.57e-03112442C0598608
DiseaseNonsyndromic genetic hearing loss

CDH23 GRHL2 STRC SLC26A5

3.67e-03762444cv:C5680182
Diseasecreatinine measurement

SPEG ADGRV1 GRHL2 CASZ1 MFAP4 PTPN12 DLC1 LIPH NLRC3 NPHS1 KIF26B NR1H3 CUBN IGF1R NCOA7 CGNL1 SOS2

4.00e-0399524417EFO_0004518
Diseasemelanoma

ADGRV1 HMCN2 DLGAP4 CNTNAP4 ATM

4.03e-031262445EFO_0000756
Diseaseage at menarche

USP34 NXPE2 ADCY3 PRDM2 PTK7 EEF1AKMT4-ECE2 FLT3 FOXJ3 CMIP IGF1R SLIT3 GREB1

4.15e-0359424412EFO_0004703
Diseasefeeling miserable measurement

HLA-B CLUH NR1H3 KANSL1

4.22e-03792444EFO_0009598
Diseasecheekbone morphology measurement

RYR2 SERTM1

4.26e-03122442EFO_0007847
Diseasekidney disease (implicated_via_orthology)

KIRREL2 NPHS1 CUBN

4.72e-03412443DOID:557 (implicated_via_orthology)
DiseaseJT interval

KIAA0232 CASZ1 TTC7B CLUH DTL IGF1R NCOA7

4.75e-032482447EFO_0007885
Diseasetestosterone measurement

SLC17A2 DCHS2 ADAR ADCY6 NF1 PTPRF SPOCD1 NRDE2 DRG2 SGCD CAMP DLGAP4 CMIP HMCN1 SUSD1 CD68 GREB1 HERC4 SOAT1 SOS2

4.82e-03127524420EFO_0004908
Diseaseelectrocardiography

MYCBP2 SPEG ADAR CASZ1 PTPN12 HMCN2 NR3C2 EMB IGF1R NCOA7 PCNX1

4.89e-0353024411EFO_0004327
DiseaseFamilial idiopathic steroid-resistant nephrotic syndrome

NPHS1 CRB2

5.00e-03132442cv:C4273714
Diseasehigh grade glioma (is_implicated_in)

ATRX NF1 IGF1R

5.05e-03422443DOID:3070 (is_implicated_in)
Diseaserenal cell carcinoma

SLC6A18 ATM PDZD2

5.05e-03422443EFO_0000681
Diseasehormone measurement

RYR2 MYO3B SGCD RESF1

5.25e-03842444EFO_0004730
Diseaseejection fraction measurement

GRIA4 HMCN1 EMCN

5.40e-03432443EFO_0005527
Diseaseschizophrenia, type 2 diabetes mellitus

MYCBP2 EMB TRMT61A

5.40e-03432443MONDO_0005090, MONDO_0005148
DiseaseDystonia

SLC46A1 ADAR ADCY5 ATM

5.70e-03862444C0013421
Diseaseurate measurement, bone density

WDR64 ITGB6 CASZ1 TIAM2 SEC16A NR3C2 SGCD SLC26A5 GRID1 DNAH1 TG PDZD2

5.72e-0361924412EFO_0003923, EFO_0004531
Diseaseage-related hearing impairment

CDH23 TMEM200A LRFN2 DLC1 SPOCD1 SLC26A5 SPAG17 MDGA1

5.79e-033242448EFO_0005782
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

ABCA1 NPHS1

5.80e-03142442DOID:10976 (biomarker_via_orthology)
DiseaseKuhnt-Junius degeneration (is_marker_for)

CCR2 IGF1R

5.80e-03142442DOID:10873 (is_marker_for)
Diseaseglycodeoxycholate measurement

SERTM1 COL7A1

5.80e-03142442EFO_0010493
Diseasepimelic acid measurement, 3-methyladipic acid measurement

ABCA1 KIAA0232

5.80e-03142442EFO_0010449, EFO_0010524
DiseaseGastric Adenocarcinoma

SPEG TLK2 ATM

6.14e-03452443C0278701
Diseasechenodeoxycholate measurement

SLC22A20P HMCN1

6.66e-03152442EFO_0010471
Diseaselow density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor

CSMD2 ADAMTS6

6.66e-03152442EFO_0004611, EFO_0005658
Disease3-hydroxyanthranilic acid measurement

PCNX2 TG

6.66e-03152442EFO_0010447
Diseaseglycerate measurement

ZSCAN10 HMCN1

6.66e-03152442EFO_0021029
DiseaseGraves' disease (is_marker_for)

TG IGF1R

6.66e-03152442DOID:12361 (is_marker_for)
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

HLA-B KIR3DL3

6.66e-03152442EFO_0801746
Diseasechronotype measurement

USP34 MYCBP2 VWA8 NXPE2 ADCY3 ADCY5 PLCB4 PCYOX1 SGCD SLC26A5 DNAH1 KANSL1 MDGA1 TRIM37 SOAT1

6.97e-0388224415EFO_0008328
Diseasestroke

CASZ1 PTPRF C4orf54 ZNF106 MICAL2

7.04e-031442445EFO_0000712
Diseasevital capacity

SLC17A2 USP34 GLDN ACADS ADCY3 CASZ1 RYR2 TIAM2 PIN1 STRN3 IGSF11 ZNF106 CMIP IGF1R KANSL1 HMCN1 ADAMTS6 PDZD2 SOS2

7.32e-03123624419EFO_0004312
DiseaseKidney Failure, Chronic

ABCA1 SREBF1 CD68

7.34e-03482443C0022661
DiseaseObesity

APCDD1 ACP5 SREBF1 ADCY3 PLIN1 CD68

7.37e-032052446C0028754
Diseaselung small cell carcinoma (is_marker_for)

ATRX SKP2

7.57e-03162442DOID:5409 (is_marker_for)
Diseasesarcoidosis (is_implicated_in)

HLA-B CCR2

7.57e-03162442DOID:11335 (is_implicated_in)
Diseasebody surface area

BRPF3 TIAM2 MAP3K3 LRFN2 DLC1 EEF1AKMT4-ECE2 DTL GRID1 UTP18 IGF1R SLIT3 NCOA7

7.63e-0364324412EFO_0022196
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

SETD1B ADCY5 NF1

7.78e-03492443EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Diseasealbuminuria

NXPE2 NR3C2 SERTM1 CUBN

7.78e-03942444EFO_0004285
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

ABCA1 HLA-B SLC46A1 LRFN2 NR1H3 DNAH1 CMIP

8.05e-032742447EFO_0004530, EFO_0004612
Diseasemonocyte percentage of leukocytes

NLRP12 HLA-B KIAA0232 NBPF4 CDH23 ADCY5 CCR2 NF1 SEC16A FLT3 GPR88 LRRC25 KANSL1

8.22e-0373124413EFO_0007989

Protein segments in the cluster

PeptideGeneStartEntry
CAFQNDLLTSSGFTL

UMODL1

1081

Q5DID0
DLFSTLCNDLVNSAQ

TMEM59L

151

Q9UK28
LCNDLVNSAQGFVSS

TMEM59L

156

Q9UK28
RATADTCQSIQNLFG

C2orf16

916

Q68DN1
SCNLFSGNESSKLEN

CCDC186

26

Q7Z3E2
SFDCIQQTFSSSGAS

ELL2

96

O00472
QQTFSSSGASQLNCL

ELL2

101

O00472
SSGASQLNCLGFIQD

ELL2

106

O00472
CQDSAALTSTAFSGL

ALG13

146

Q9NP73
SLQLGSSISFLCDEG

CSMD2

706

Q7Z408
QFGLSFESLCLTVNT

CCNO

146

P22674
SCANLFIGINSSAIT

ABCA4

1796

P78363
ASQALGIAQTALDCA

ACADS

276

P16219
DVISAAGFCQFSSSA

CASZ1

1541

Q86V15
EGFTSLASQCTAQEL

ADCY6

386

O43306
SFSTISQALCSQGIT

ABCA12

721

Q86UK0
SCNFLATVVASVGAQ

GTPBP3

346

Q969Y2
ISTLFSRANLAAACG

ABCA1

736

O95477
CATAEAQSTLNCTFT

ADGRG2

176

Q8IZP9
LLCDSSNFTCQTEGA

ACVR1C

31

Q8NER5
TENFAFSLLTNVTCG

ADGRV1

5716

Q8WXG9
NLSLAFTNVTSACAE

CMIP

666

Q8IY22
TCQFLALSQSCSASE

CFAP46

2081

Q8IYW2
LGNFSDLQIDSCGIS

CNTNAP4

536

Q9C0A0
FFSQANTAALCTSLV

ABCA13

3671

Q86UQ4
VNQTFLCLLSTTAFG

ABCA13

3706

Q86UQ4
SSGAQQSLIDEDAFC

BRPF3

201

Q9ULD4
SLSFCLAQLAAAAGE

ARMC5

11

Q96C12
LSALNAAGTVFALCQ

GLDN

26

Q6ZMI3
SCSLRSFQNFISNVG

ADAM32

361

Q8TC27
ATLLTRSLNCNTTFG

CELSR1

2731

Q9NYQ6
SLILDSTGSTLFANC

DTL

276

Q9NZJ0
STGSTLFANCTDDNI

DTL

281

Q9NZJ0
EGFTSLASQCTAQEL

ADCY5

476

O95622
LLNSCFLISSFNGTD

CD163L1

31

Q9NR16
SDADSGCNARLTFNI

CDH23

1876

Q9H251
SDSLNDSSCISQIFG

DLGAP4

441

Q9Y2H0
DSSCISQIFGQASLI

DLGAP4

446

Q9Y2H0
GTALAIDSNSCFEIQ

GKN3P

151

P0CG01
SCSINEDIGLGSAFT

ADAMTS6

386

Q9UKP5
NALCTQISSSFASAG

NUMBL

361

Q9Y6R0
NGLAQRGLSSTTCSF

NBPF4

526

Q96M43
IFVGNVSAACTSQEL

RBM14

81

Q96PK6
GTLQSNFCASSLVVT

PCOLCE

326

Q15113
EVPQSSNTSLASFCN

PIK3C2G

236

O75747
FVCQSSSIDFLASQG

PARN

106

O95453
CSSLTDFFLLGITNN

OR5W2

6

Q8NH69
QDASSQAQGGSSCIL

NR1H3

26

Q13133
LGQSFSCSNSSIILS

CD68

271

P34810
SVSNDVGSAACLFQV

MDGA1

616

Q8NFP4
CSSNSTGVLEAANNS

EMCN

16

Q9ULC0
ALFTCTATNALGSDQ

NPHS1

916

O60500
LLTASLSFCGNQEVA

OR1A2

161

Q9Y585
TEQGALFSAVACVNS

SLC46A1

386

Q96NT5
ASVATNFLLGITANC

LRRC55

271

Q6ZSA7
NLASQSVLEGLNACF

MDN1

1826

Q9NU22
LLNASITETFNCSFS

KCNMB2

86

Q9Y691
SNAFIVNGCAADLSV

GPR88

66

Q9GZN0
FSSSCLGGNSKINSD

NR3C2

406

P08235
GATESATIRNDFLCN

MCMDC2

171

Q4G0Z9
SDACAQEANLSLSLS

NLRC3

611

Q7RTR2
CSIADSSTQNLDLGS

GREB1

676

Q4ZG55
SNSACETGSVSALFQ

MTUS1

621

Q9ULD2
ISSAQLGDATFAGCL

CRB2

566

Q5IJ48
SSSAESFGLFSCIIN

MAPK8IP1

471

Q9UQF2
NTSLTQCNFLSECGF

FNDC7

331

Q5VTL7
QLQALSTADSGDYSC

HMCN2

3651

Q8NDA2
FELCGDVTLQANNTS

KATNIP

161

O60303
AEFSATCLNFSGLSL

LRRC25

36

Q8N386
TLRDSGTFTCIASNA

LRFN1

361

Q9P244
FVDGSVSGCSTNNLN

MGAM

536

O43451
ISFNSDCSARALASG

KIF26B

1211

Q2KJY2
FCANILSAESSDSEG

IGF1R

281

P08069
SCLATNELGSAESSV

ISLR

326

O14498
IETANSFAVTNAFCS

GRIA4

71

P48058
LSLDSGTVACLNDSN

PCNX1

691

Q96RV3
DLEASSCSSTQGKFN

PCNX2

791

A6NKB5
INAFVGAVSLSCSDS

PCYOX1

231

Q9UHG3
LASQFSDCSSAKARG

PIN1

106

Q13526
LNLSFTAICNNGTLF

ITGB6

386

P18564
SDINEGSGINSCFSV

KIAA0232

636

Q92628
LNSVASTDSISFLGC

OR14K1

81

Q8NGZ2
CGQNSSLGSFSIITE

MUC2

891

Q02817
SLSSCSENQSEAGTL

PDZD2

2396

O15018
SDFSVGADTALNTIC

PFKM

536

P08237
SSSGCLNGSFLAVSN

HERC4

431

Q5GLZ8
AGENVTLSCSSRSLF

KIR3DL3

236

Q8N743
FCVGSITSLSQQTEA

NRDE2

31

Q9H7Z3
SGIANLRCSEQAFDS

KANSL1

386

Q7Z3B3
SLTSVGFGNVCANTD

KCNH4

436

Q9UQ05
LSFNNISSFDSVSCL

LRRC49

251

Q8IUZ0
LTCAQTINSSAFGNL

LIPH

51

Q8WWY8
TATGCQSLASALVSN

NLRP5

936

P59047
CLNSRETSFITNGSC

IL12A

96

P29459
CGSISSANILLDDQF

IRAK3

291

Q9Y616
FANSSAELTGCLVRS

OSTM1

91

Q86WC4
LASSCCSSNILGSVN

ODF1

116

Q14990
TCVLENSSSFSLDQG

FAAP100

526

Q0VG06
QAACSDSAQGSDVSL

HLA-B

346

P01889
SSTALSVANCLGAQT

IQSEC3

501

Q9UPP2
SALLFSSCFVANDST

ALAS2

251

P22557
DGNAASVTSLSNLAC

NPHP4

371

O75161
CLASNSAGTDKQNST

HMCN1

681

Q96RW7
SAASIACFLAANGAD

MIB1

751

Q86YT6
SIFSGNEDGVLSLCS

DCHS2

2176

Q6V1P9
STQFTAANELACRGL

PLIN1

81

O60240
TIGLSAAARFNQCNT

ALPP

131

P05187
LAASLSCSGTIQGTN

F2RL1

16

P55085
RNLSLQVAFSGATAC

PDP2

256

Q9P2J9
TISFEDFNLQNSSGC

CUBN

2376

O60494
VLAEASASQASCFSD

FLT3

441

P36888
QDSLASFSQFISDTC

DNAH1

616

Q9P2D7
SFSQFISDTCCSVLN

DNAH1

621

Q9P2D7
QTCISNTDDALGFAL

EEF1AKMT4-ECE2

546

P0DPD8
NSSASQSTDLCDFSG

ATM

1356

Q13315
ENLVLSSHTGFCQSS

ATRX

1231

P46100
SALSSGLYQCVASNA

IGSF11

206

Q5DX21
ASQTQCNSSSDGKLA

GRHL2

441

Q6ISB3
NAEFLTCNIPTSNAS

ADAR

386

P55265
VLNNTERCLAGTSFS

CGNL1

56

Q0VF96
FQVDCSSAGSAELTI

FLNA

1181

P21333
ADLCSSLNQFFTQTG

FOXJ3

506

Q9UPW0
QGDRFLTDVTCASSA

FRMPD4

1146

Q14CM0
VDTALQNFASTFCSG

ARFGEF3

696

Q5TH69
SCQADLASSLSNAVQ

POLQ

246

O75417
GGFSSTQDTCVALQA

CPAMD8

1411

Q8IZJ3
ASTATLQASLDACQA

CEP250

1996

Q9BV73
VLFTISDGNTDSCFN

FAT3

761

Q8TDW7
VGFTQLSSACSAQEL

ADCY3

326

O60266
AATASLLNVFNGNEC

APCDD1

376

Q8J025
FFGLSNCESTSQLDQ

CCR2

271

P41597
TVTLNQARGSFDISC

CAMP

111

P49913
DTNNETCTAGAGSLL

EDEM1

296

Q92611
AAQTCQRLNGSLATF

DGCR2

141

P98153
VTSTGCASANALQSL

GRID1

91

Q9ULK0
ISGTQESDFSRSFNC

KIRREL2

471

Q6UWL6
GNASNSCTVLSLLGA

KHK

41

P50053
LCGDQVTFSSDQTLT

KLF18

181

A0A0U1RQI7
VSGLATALCQASFTT

COL7A1

1226

Q02388
CSNLATLNLNSGSSG

DVL1

501

O14640
LTCQFTTSGDLNAVN

EMB

86

Q6PCB8
SSATNAEFAQTLGAA

SDR39U1

221

Q9NRG7
CSNLATLNLNSGSSG

DVL1P1

476

P54792
AAAASSCGSAASQIL

C4orf54

506

D6RIA3
QSEFASVCTSNSILD

SLC22A20P

316

A6NK97
VVGFQLCSNDTSDCA

SCNN1G

201

P51170
GFGNRLCFLESTSNS

RYR2

41

Q92736
ENSLSGSCQSLDRSA

MAP3K3

221

Q99759
NFSSRSLGSNQECGS

MICAL2

691

O94851
ASSAFSSVCNQQPLD

PRDM2

811

Q13029
CFISSVTFCGSNVLN

OR6B2

161

Q6IFH4
SAFCFSTGQGLAALS

PKD1

211

P98161
ECTATNSLGEINTSA

PTPRF

106

P10586
SLSTLGSANCFLDSL

HSPA14

271

Q0VDF9
SLQDFSVFSTDSCLQ

HOXA2

321

O43364
LLTASLSFCGNQEVA

OR1A1

161

Q9P1Q5
ANLSLTDACFTSASI

OR1N2

81

Q8NGR9
LFSTSQEGLSSLCSD

RTN3

61

O95197
ACFSANGEEVLATST

UTP18

301

Q9Y5J1
VLSLAISSNGEQCFS

STRN3

536

Q13033
LTENGQVLSCGSNSF

SERGEF

116

Q9UGK8
TSLFSADQAALAACG

TRIM37

711

O94972
SLDNGGCALTTFSVL

SOAT1

86

P35610
SVFLDVDLNSSCGSN

SOS2

1101

Q07890
ATCSVQVISGQFLSD

PLCB4

701

Q15147
CASRLAANTIASFSG

TMEM200A

201

Q86VY9
LDSSLESTLDNSCQG

NCOA7

606

Q8NI08
NGLAQRGLSSTTCSF

NBPF6

526

Q5VWK0
ANRSSNVFTECGLTL

NXPE2

221

Q96DL1
STSNVSGRVLDNSFC

RESF1

636

Q9HCM1
CNSIGSLFQTFSISC

SLC26A5

381

P58743
DQDLFVQNCAALSSG

MFAP4

191

P55083
LSSDLNVGDTSQNSC

PTPN12

481

Q05209
NCSSATFTGNLSFLA

SIMC1

141

Q8NDZ2
ALTIDDICFSLNNNS

TEKT1

181

Q969V4
CGGSIQTSVNALSAD

CCT7

326

Q99832
NTIFSFGSTLCQDIS

SPATA31D4

266

Q6ZUB0
SSFTGSCDSDLLKFN

SETD1B

1806

Q9UPS6
NELFSSHLVSNTCGL

MYCBP2

1681

O75592
ACFLGSAQSENVLTD

WRN

616

Q14191
ANVCLAAAVTQTLSF

SLC25A43

206

Q8WUT9
SDAGSSFTNLEVCSI

SERTM1

81

A2A2V5
GISFNSTVTLTQCSE

DRG2

186

P55039
LILCNSFSDTSIFNQ

SPG21

131

Q9NZD8
CFISSVTFCGSNVLN

OR6B3

161

Q8NGW1
DADLASCGSLSQSSA

PHLDB2

516

Q86SQ0
ESQSLDSGSCSALQN

SFR1

126

Q86XK3
VISVCSSSNLAGNDD

DLC1

621

Q96QB1
TGEAAISRSFQSLAC

PDLIM2

146

Q96JY6
LDAICSNLSFSALSG

STRC

421

Q7RTU9
SFSATLENGICLSIS

SPAG17

1121

Q6Q759
VCFLSATCFTLQSGN

SLC6A18

451

Q96N87
VNSIAASAVCVFNLS

SEMA5A

311

Q13591
FLSSARQACLAQSGS

SREBF1

741

P36956
NSESSNQSLCSVGSL

TLK2

31

Q86UE8
GNFSCTDINECLTSS

ADGRE1

126

Q14246
VVSISACSLFSGHAN

BPIFB2

131

Q8N4F0
NSADCQFSVFALTTI

CLDN34

6

H7C241
FQQCEAGSSTTGELS

CKAP2L

121

Q8IYA6
CLELSLQSGNSTDFT

CLSPN

131

Q9HAW4
DAFNGVDCNSLSFLS

CLUH

146

O75153
GSDLSFSCRLQDTNS

CAMK2N2

21

Q96S95
LIGCVSNDTFAGLSS

SLIT3

616

O75094
CTFSSVIAGLSTFLN

SLCO2A1

336

Q92959
NLSGCSGFSEFALQT

SKP2

236

Q13309
SGFSEFALQTLLSSC

SKP2

241

Q13309
SGDTGSLSCDNALFV

DNTTIP2

476

Q5QJE6
LEAQALSATGQSCAE

TNRC18

1201

O15417
NTIFSFGSTLCQDIS

SPATA31D3

266

P0C874
SCQACGRSFTQSSQL

ZSCAN10

496

Q96SZ4
SISENDNGISFTCRL

TMIGD1

91

Q6UXZ0
CLSNSLGDAFLFQTT

TIAM1

516

Q13009
ITALCRSFNDSQANG

TIAM2

1061

Q8IVF5
GIFCASLNFIDSTNT

PIGT

136

Q969N2
AQLAQACATSGSSRL

SEC16A

2331

O15027
LGDRLSSGSCQAFNS

SPATA46

231

Q5T0L3
ATNELGQATCAASLT

SPEG

796

Q15772
GALNTNASFGCAVST

TRO

1061

Q12816
SLCFGSASNTNLCFG

TRO

1156

Q12816
FLSQAGAGSTCQINT

SGCD

271

Q92629
NLSAESCGLNSGAQF

STOX1

816

Q6ZVD7
SFSACSLALDQAQLT

TONSL

1046

Q96HA7
LSLNTIFSFGSTLCQ

SPATA31D1

266

Q6ZQQ2
IFSFGSTLCQDISQA

SPATA31D1

271

Q6ZQQ2
AALCLGASAQASAEQ

SPOCD1

326

Q6ZMY3
GLSEQIDGSALSCFS

STAMBPL1

201

Q96FJ0
LALQSTFSCDSEGAS

SUSD1

626

Q6UWL2
ECSECGKSFSQSSNL

ZNF256

576

Q9Y2P7
EECGQAFSRSSTLAN

ZNF679

271

Q8IYX0
TCQALAARGFSELST

TRMT61A

216

Q96FX7
TSNLCDSGFIINTLD

SLC17A2

386

O00624
SSCVSASGNFNISAD

TCN1

306

P20061
KSCQSSASAVDFGAS

ZDBF2

1701

Q9HCK1
STFLDAGSVNSCSAV

XPO5

471

Q9HAV4
NSASGVLFSLSCNNF

NF1

136

P21359
LLQSLASGGNDCTTS

NUP188

361

Q5SRE5
DTVTLCGNSDDFLSQ

ACP5

156

P13686
LVSINSNASAGCFAF

STAB1

306

Q9NY15
LYLCEASNALGNAST

SIGLEC1

686

Q9BZZ2
CEATNVLGSSNTSLF

SIGLEC1

876

Q9BZZ2
ICEASNTLGQASASA

SIGLEC1

1066

Q9BZZ2
TTNVNSIAASAVCAF

SEMA5B

376

Q9P283
SIAASAVCAFNLSAI

SEMA5B

381

Q9P283
LDAAGSFDNSSLCSG

WDR83

71

Q9BRX9
ECLSSVATALQSGFL

TNPO1

596

Q92973
LSCFGGLNASIFASS

SLC7A6

326

Q92536
EECGRAFSQSSTLTA

ZNF492

256

Q9P255
QGNDAAATECFLTAL

TTC7B

811

Q86TV6
NECGKLFSQSSSLNS

ZNF792

481

Q3KQV3
VAAATSSLCEAANAS

TLN2

2401

Q9Y4G6
LDAICSNLSFSALSG

STRCP1

421

A6NGW2
SQVFSEANCANLIST

USP34

3246

Q70CQ2
QDTGACLFTLSLDGS

WDR31

311

Q8NA23
FATTLCSQESSTLGL

VWA8

296

A3KMH1
FGQACSSQNFTLSIA

PTK7

206

Q13308
STAATSNFSAVRDLC

TG

2116

P01266
GANSTLRCNFSDSVN

TRAV22

36

A0A0B4J277
EGNCLSSSASSALAI

ZNF106

976

Q9H2Y7
FSESQGLNCSDTLNR

ZNF541

21

Q9H0D2
ISALNCFGSCSLDSN

WDR64

286

B1ANS9
SLYQASLQASQAGCS

USP54

1321

Q70EL1
TATAVDITSCGNFAV

WDR36

496

Q8NI36
QLCDNSVGVLFNDST

PLK1

426

P53350
SQDSGAFTCIAANAA

LRFN2

351

Q9ULH4
AACDELASTLSVNQS

NLRP12

871

P59046
VNSLVEAFGNSCTAI

MYO3B

471

Q8WXR4
ATFFDRNTLANSCGT

NACC2

381

Q96BF6