Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsmall GTPase binding

PLEKHG1 RAPGEF6 CYFIP1 SGSM2 DOCK9 NPC1L1 PPP6R1 ADCYAP1R1 XPOT PLCE1

9.66e-073218410GO:0031267
GeneOntologyMolecularFunctionGTPase binding

PLEKHG1 RAPGEF6 CYFIP1 SGSM2 DOCK9 NPC1L1 PPP6R1 ADCYAP1R1 XPOT PLCE1

2.71e-063608410GO:0051020
DomainARM-type_fold

PIK3C2A NBEAL2 DOCK9 ASPM PPP6R1 TRRAP GPRASP2 XPOT

1.20e-04339828IPR016024
DomainRASGEF_CAT

RAPGEF6 RAPGEF2 PLCE1

2.74e-0429823PS50009
DomainRasGEF

RAPGEF6 RAPGEF2 PLCE1

3.04e-0430823PF00617
Domain-

RAPGEF6 RAPGEF2 PLCE1

3.04e-04308231.10.840.10
DomainRas_GEF_dom

RAPGEF6 RAPGEF2 PLCE1

3.04e-0430823IPR023578
DomainRASGEF_cat_dom

RAPGEF6 RAPGEF2 PLCE1

3.04e-0430823IPR001895
DomainRasGEF

RAPGEF6 RAPGEF2 PLCE1

3.04e-0430823SM00147
DomainRA

RAPGEF6 RAPGEF2 PLCE1

3.36e-0431823SM00314
DomainRA

RAPGEF6 RAPGEF2 PLCE1

5.25e-0436823PF00788
DomainRA

RAPGEF6 RAPGEF2 PLCE1

5.69e-0437823PS50200
DomainRA_dom

RAPGEF6 RAPGEF2 PLCE1

7.17e-0440823IPR000159
DomainUbiquitin-rel_dom

PIK3C2A FRMPD2 RAPGEF2 ARAF PLCE1

1.30e-03184825IPR029071
Domain-

PIK3C2A TRRAP

2.20e-03168221.10.1070.11
DomainPI3Kc

PIK3C2A TRRAP

2.20e-0316822SM00146
DomainPH_dom-like

PLEKHG1 NBEAL2 DOCK9 FRMPD2 MTMR3 MYO1B PLCE1

2.67e-03426827IPR011993
DomainRUN

SGSM2 RUSC1

2.78e-0318822SM00593
DomainPI3/4_kinase_cat_dom

PIK3C2A TRRAP

2.78e-0318822IPR000403
DomainPI3_PI4_kinase

PIK3C2A TRRAP

2.78e-0318822PF00454
DomainPI3_4_KINASE_3

PIK3C2A TRRAP

2.78e-0318822PS50290
DomainPI3_4_KINASE_1

PIK3C2A TRRAP

2.78e-0318822PS00915
DomainPI3_4_KINASE_2

PIK3C2A TRRAP

2.78e-0318822PS00916
DomainRUN

SGSM2 RUSC1

3.10e-0319822PS50826
DomainRUN

SGSM2 RUSC1

3.10e-0319822PF02759
DomainRun_dom

SGSM2 RUSC1

3.10e-0319822IPR004012
DomainRasGEFN

RAPGEF6 RAPGEF2

3.44e-0320822SM00229
DomainRasGEF_N

RAPGEF6 RAPGEF2

3.79e-0321822PF00618
DomainRas-like_Gua-exchang_fac_N

RAPGEF6 RAPGEF2

4.15e-0322822IPR000651
DomainRASGEF_NTER

RAPGEF6 RAPGEF2

4.15e-0322822PS50212
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

FANCD2 SUPT20H HNRNPM ASPM ZBTB10 PPP6R1 ABHD8 ITGA3 RSRC2 RAPGEF2 EZH1 TRRAP SLC40A1 ARAF MYEF2 ALG13

9.36e-091116841631753913
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

UBE4A NRDE2 SLC7A2 SUPT20H CENPE DOCK9 ASPM PRAMEF1 XPOT

2.46e-0736384914691545
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYP1B1 NRDE2 UXS1 GTF2H3 CYFIP1 SUPT20H POLR1A GTF3C2 PIK3C2A SLC25A1 RSRC2 MICU2 SPEN TRRAP ARAF MYEF2

5.14e-071497841631527615
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

FANCD2 GTF2H3 POLR1A SLC25A1 CHD1L TRRAP

1.79e-0615084630154076
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CYFIP1 SUPT20H POLR1A CENPE NBEAL2 DOCK9 TRRAP ARAF XPOT

3.29e-0649784936774506
Pubmed

Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.

HIGD2A HIGD2B

5.76e-06284232085461
Pubmed

Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress.

HIGD2A HIGD2B

5.76e-06284235008815
Pubmed

The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.

RAPGEF6 RAPGEF2

5.76e-06284224858808
Pubmed

HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.

HIGD2A HIGD2B

5.76e-06284237041638
Pubmed

Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.

RAPGEF6 RAPGEF2

5.76e-06284232600317
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PLEKHG1 RAPGEF6 PIK3C2A MTMR3 PPP6R1 RAPGEF2 ARAF ALG13

1.28e-0544684824255178
Pubmed

Identification of a protein mediating respiratory supercomplex stability.

HIGD2A HIGD2B

1.73e-05384222405070
Pubmed

Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.

RAPGEF6 RAPGEF2

1.73e-05384229747665
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CYFIP1 POLR1A GTF3C2 PIK3C2A SLC25A1 HNRNPM ASPM ZBTB10 MYO1B CHD1L TRRAP MYEF2 XPOT

2.12e-051353841329467282
Pubmed

CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression.

CENPE PLK4

3.45e-05484233176597
Pubmed

Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.

HMCN1 LAMA2

3.45e-05484234504132
Pubmed

BMP1-like proteinases are essential to the structure and wound healing of skin.

TLL1 LAMA2

3.45e-05484227363389
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FAT2 HMCN1 DTX1 ATP9B DNAH11

3.49e-0515284534299191
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLEKHG1 SGSM2 DOCK9 MTMR3 PPP6R1 SPEN PLCE1

5.96e-0540784712693553
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RAPGEF6 GTF3C2 ZBTB10 RUSC1 PPP6R1 ARAF GPRASP2

7.04e-0541884734709266
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLEKHG1 RAPGEF6 RARG SGSM2 NBEAL2 DOCK9 MTMR3 PPP6R1 ITGA3 SPEN TRRAP

7.07e-051105841135748872
Pubmed

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.

TRAP1 HNRNPM

8.59e-05684218790094
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

GTF2H3 POLR1A GTF3C2 HNRNPM ZBTB10 TRRAP MYEF2

9.69e-0544084734244565
Pubmed

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.

ITGA3 RSRC2 TRRAP LPAR1 MYEF2 WDFY1

1.01e-0430684618973680
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

FANCD2 TRAP1 HIGD2A MYO1B CHD1L PPP6R1 ARAF XPOT

1.11e-0460684836538041
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

MTMR3 RAPGEF2 EZH1 MICU2

1.21e-041048449205841
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

FANCD2 GTF3C2 SLC25A1 TRRAP XPOT

1.64e-0421184517314511
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

TRAP1 CYFIP1 SLC25A1 RAPGEF2 XPOT

1.87e-0421784530619736
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

TRAP1 CYFIP1 SLC25A1 HNRNPM MYO1B XPOT

1.91e-0434484636282215
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

HNRNPM ZBTB10 TRRAP MYEF2 XPOT

1.99e-0422084535785414
Pubmed

Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner.

PLEKHG1 TLL1

2.05e-04984224663101
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

HNRNPM MYO1B TRRAP XPOT

2.10e-0412084427320910
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

UBE4A GTF3C2 ZBTB10 CHD1L PPP6R1 RSRC2 SPEN TRRAP MYEF2

2.27e-0485784925609649
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

FANCD2 CYP1B1 HIGD2A FAM20B HNRNPM ITGA3 LPAR1 MYEF2 XPOT ALG13

2.40e-041061841033845483
Pubmed

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.

RAPGEF6 RAPGEF2

2.56e-041084223885123
Pubmed

Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.

LAMA2 ITGA3

2.56e-041084218590826
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

FANCD2 GTF3C2 ASPM PPP6R1 TRRAP GPRASP2

2.58e-0436484624778252
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FAT2 CENPE HNRNPM ASPM MYO1B

2.65e-0423484536243803
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NRDE2 RAPGEF6 KCNJ3 DOCK9 FAM20B ZBTB10 HINT3 PRAMEF1 WDFY1 XPOT

2.84e-041084841011544199
Pubmed

USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma.

HNRNPM MYO1B

3.13e-041184235449157
Pubmed

Gene and microRNA expression in p53-deficient day 8.5 mouse embryos.

RARG ITGA3

3.13e-041184219229884
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

RAPGEF6 CENPE MTMR3 ASPM RSRC2

3.39e-0424784532989298
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

GTF3C2 MTMR3 ASPM ARAF

3.68e-0413984425476789
Pubmed

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.

LAMA2 ITGA3

3.75e-041284211381080
Pubmed

Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.

LAMA2 ITGA3

3.75e-041284212843252
Pubmed

Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex.

RAPGEF6 RAPGEF2

4.42e-041384227390776
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

POLR1A SLC25A1 HNRNPM MYO1B ARAF GPRASP2 XPOT

4.43e-0456584733567341
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CYFIP1 SUPT20H CENPE ASPM MYO1B PPP6R1 SPEN

5.61e-0458884738580884
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

RAPGEF6 RAPGEF2

5.93e-041584222797597
Pubmed

Laminin alpha5 chain is required for intestinal smooth muscle development.

LAMA2 ITGA3

5.93e-041584212921739
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

UBE4A TRAP1 SGSM2 HNRNPM ZBTB10

6.39e-0428484529459677
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA2 ITGA3

6.77e-041684217601529
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

CENPE HNRNPM LAMA2 RUSC1 MYO1B CHD1L RAPGEF2 LPAR1 MYEF2 OPLAH

6.92e-041215841015146197
Pubmed

ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.

FAT2 ASPM

7.66e-041784226581405
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

FANCD2 UBE4A TRAP1 HIGD2A GTF3C2 CENPE PIK3C2A MTMR3 MICU2 ARAF ALG13

9.36e-041496841132877691
Pubmed

Rrn3 becomes inactivated in the process of ribosomal DNA transcription.

GTF2H3 POLR1A

9.60e-041984212646563
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NRDE2 RAPGEF6 TLL1 PPP6R1 MICU2 ARAF PLCE1

1.01e-0365084738777146
Pubmed

Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module.

SUPT20H TRRAP

1.06e-032084227601583
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA2 ITGA3

1.06e-032084222911573
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

NPHP1 DNAH11

1.06e-032084217251353
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

NRDE2 SUPT20H SLC25A1 HNRNPM MYO1B RSRC2 SPEN TRRAP MYEF2

1.20e-03108284938697112
Pubmed

Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex.

LAMA2 ITGA3

1.29e-032284226733533
Pubmed

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.

GTF2H3 POLR1A

1.29e-03228429582279
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

HNRNPM SPEN TRRAP MYEF2

1.30e-0319584419454010
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

FANCD2 TRAP1 GTF3C2 HNRNPM MTMR3 ZBTB10 PPP6R1 TRRAP GPRASP2 OPLAH

1.41e-031335841029229926
Pubmed

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.

EZH1 TRRAP

1.41e-032384231281901
Pubmed

Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter.

GTF2H3 POLR1A

1.41e-032384212393749
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

NRDE2 TRAP1 POLR1A SLC25A1 PPP6R1 ARAF MYEF2

1.55e-0370184730196744
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

NRDE2 GTF2H3 CYFIP1 POLR1A MYO1B TRRAP PLK4 ARAF

1.61e-0391084836736316
Pubmed

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

UXS1 FAM20B

1.80e-032684233905568
Pubmed

VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.

ASPM ADCYAP1R1

1.95e-032784221737879
Pubmed

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.

SUPT20H TRRAP

1.95e-032784218838386
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

HNRNPM TRRAP

1.95e-032784223395962
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TRAP1 PIK3C2A PPP6R1 WDFY1

1.96e-0321884433378226
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

FANCD2 POLR1A SLC25A1 FAM20B HNRNPM PPP6R1 GPRASP2 XPOT

2.00e-0394284831073040
Pubmed

IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

UBE4A CYFIP1 PIK3C2A MYO1B

2.06e-0322184431950832
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

TRRAP ARAF XPOT

2.08e-0310484331240132
Pubmed

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

SUPT20H TRRAP

2.09e-032884219114550
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RAPGEF6 CYFIP1 GTF3C2 SLC25A1 SPEN TRRAP

2.16e-0354984638280479
Pubmed

Identification of cathepsin K as a novel marker of adiposity in white adipose tissue.

NPHP1 TRAP1

2.24e-032984212652657
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

HNRNPM TRRAP MYEF2

2.25e-0310784320508642
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FANCD2 UBE4A TRAP1 CYFIP1 POLR1A GTF3C2 HNRNPM MYO1B SPEN XPOT

2.27e-031425841030948266
Pubmed

CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

SLC25A1 HNRNPM GPRASP2

2.31e-0310884330166453
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

UBE4A TRAP1 CYFIP1 GTF3C2 MYO1B XPOT

2.39e-0356084635241646
Pubmed

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

SUPT20H TRRAP

2.40e-033084218206972
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

SPEN TRRAP

2.40e-033084226593974
Pubmed

Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy.

TRAP1 HNRNPM

2.40e-033084235152003
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SUPT20H GTF3C2 CENPE PIK3C2A DOCK9 MTMR3 MYO1B RAPGEF2 MICU2 SPEN TRRAP LPAR1 PLCE1

3.23e-068568413M4500
CoexpressionGSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP

UBE4A SGSM2 NBEAL2 DOCK9 PPP6R1 SPEN XPOT

3.62e-06199847M3257
CoexpressionGSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP

PRDM8 RARG VSTM2A ASPM PANK1 WDFY1 OPLAH

3.74e-06200847M3529
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

CYP1B1 SLC7A2 HMCN1 CENPE LRFN5 KCNJ3 ASPM LAMA2 SLC41A1 PANK1 SLC40A1 LPAR1 ADCYAP1R1 PLCE1

8.85e-077737914gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

UXS1 MYO1B KCNT1 ADCYAP1R1 PLCE1 DNAH11

1.57e-061898469c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

PLEKHG1 CYP1B1 HMCN1 PIK3C2A TLL1 DOCK9

1.57e-0618984675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

PLEKHG1 CYP1B1 HMCN1 PIK3C2A TLL1 DOCK9

1.57e-06189846c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 PRDM8 HMCN1 LAMA2 LPAR1 ADCYAP1R1

1.72e-06192846d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

PLEKHG1 CYP1B1 HMCN1 PIK3C2A TLL1 DOCK9

1.77e-0619384601c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

PLEKHG1 CYP1B1 HMCN1 PIK3C2A TLL1 DOCK9

1.77e-061938462531266bc57339d4e2b22a88817008e32b8c1598
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE SLC17A2 HMCN1 TLL1 LAMA2

1.31e-05160845c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE SLC17A2 HMCN1 TLL1 LAMA2

1.31e-0516084525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE GUCY2F VSTM2A ASPM PLK4

1.53e-05165845eec2d327c94832d1390314c93ef6a2be4648478b
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 NBEAL2 PRICKLE2 MICU2 MYEF2

1.53e-051658457c771f22b58989572c939ed127e637ec28dc0dca
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC7A2 POLR1A DOCK9 ZBTB10 OPLAH

1.86e-051728453b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 PRDM8 TLL1 DOCK9 PLCE1

2.14e-05177845326fde0734ef0d7272693966d346ca479b9d8147
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 SLC22A10 PLK4 MYEF2 PLCE1

2.32e-051808450c146e80d55d18b6988dd21b1da635801bd3140c
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FANCD2 CENPE ASPM PLK4 MYEF2

2.32e-051808455e1680088065be14447d5d5465f91f7edd071a1e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 SLC22A10 PLK4 MYEF2 PLCE1

2.32e-05180845e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 SLC22A10 PLK4 MYEF2 PLCE1

2.32e-0518084511455ba704ac73f69b474845136cfecec6a88349
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PLEKHG1 DOCK9 PRICKLE2 ITGA3 ITPRID1

2.38e-05181845c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE HMCN1 GUCY2F PLCE1 DNAH11

2.57e-051848452cbed6462fea2622871bb7e49b0df3d984239281
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CYFIP1 PIK3C2A ABHD8 WDFY1 OPLAH

2.57e-051848452c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CYP1B1 HMCN1 LRFN5 TLL1 LAMA2

2.57e-0518484567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE HMCN1 GUCY2F PLCE1 DNAH11

2.57e-05184845ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE HMCN1 GUCY2F PLCE1 DNAH11

2.57e-051848452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC7A2 UXS1 MYO1B ADCYAP1R1 PLCE1

2.64e-05185845a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

FANCD2 CENPE DTX1 ASPM PLK4

2.64e-051858459766216b41ee62bbac4caa25cb98ec5627a24075
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 HMCN1 LAMA2 LPAR1 ADCYAP1R1

2.64e-05185845785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 HMCN1 LAMA2 LPAR1 ADCYAP1R1

2.64e-0518584597a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 HMCN1 LAMA2 LPAR1 ADCYAP1R1

2.71e-0518684594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC7A2 UXS1 MYO1B ADCYAP1R1 PLCE1

2.78e-05187845a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 TLL1 DOCK9 SLC22A10 PRICKLE2

2.85e-051888453953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE HMCN1 NBEAL2 MYO1B ITGA3

2.93e-05189845e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

SLC7A2 LAMA2 MYO1B ADCYAP1R1 PLCE1

2.93e-05189845d7ed96add29f219183c802895fbff519b627f635
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A2 LRFN5 LAMA2 LPAR1 ADCYAP1R1

3.08e-051918452c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FANCD2 CENPE ASPM UGT3A2 PLK4

3.16e-0519284552d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 PRDM8 LAMA2 LPAR1 ADCYAP1R1

3.16e-05192845853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

CYP1B1 PRICKLE2 LAMA2 MYO1B LPAR1

3.16e-0519284560b1312e84f6d6448365a952469c506c00b5fe93
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 PRDM8 LAMA2 LPAR1 ADCYAP1R1

3.16e-0519284549281626ecad0456fdbded2378b7028d7b589686
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A2 LRFN5 LAMA2 LPAR1 ADCYAP1R1

3.23e-0519384509a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRFN5 KCNJ3 LAMA2 GPRASP2 ADCYAP1R1

3.23e-05193845e5016959f24370579a8770787e96869f264cf7b3
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.23e-05193845acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.32e-05194845011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RARG NBEAL2 MYO1B ITGA3

3.32e-0519484546070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RARG NBEAL2 MYO1B ITGA3

3.32e-05194845abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

PLEKHG1 HMCN1 PIK3C2A TLL1 DOCK9

3.40e-05195845fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FANCD2 SLC7A2 CENPE ASPM PLK4

3.40e-05195845c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

FANCD2 CENPE ASPM HINT3 XPOT

3.48e-05196845b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

FANCD2 CENPE ASPM LAMA2 PLK4

3.48e-051968452ce8a787f2731faa913d20342d73041d59468f27
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 TLL1 DOCK9 SLC22A10 ITGA3

3.48e-0519684581278e696d823744267d6315c4d42799c4ea0b2c
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

PLEKHG1 HMCN1 PIK3C2A TLL1 DOCK9

3.57e-05197845ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CENPE ASPM PLK4 MYEF2

3.65e-051988455f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CENPE ASPM PLK4 MYEF2

3.65e-05198845629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

CYP1B1 SLC7A2 LRFN5 LAMA2 LPAR1

3.65e-05198845ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FANCD2 FAT2 CENPE ASPM PLK4

3.65e-05198845f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellproximal-Epithelial-Proliferating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 FAT2 CENPE ASPM PLK4

3.74e-05199845521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCellproximal-Epithelial-Proliferating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 FAT2 CENPE ASPM PLK4

3.74e-05199845e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCellproximal-3-Epithelial-Proliferating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 FAT2 CENPE ASPM PLK4

3.74e-051998452263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UXS1 LAMA2 MYO1B ADCYAP1R1 PLCE1

3.74e-05199845000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UXS1 LAMA2 MYO1B ADCYAP1R1 PLCE1

3.83e-05200845911db29f254bb697610e720ba78816e2c7f57933
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CYP1B1 PIK3C2A TLL1 DOCK9

3.83e-0520084584e145619a500530f42ed0fe72468ae95f4cbf1e
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.83e-05200845389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE HMCN1 LRFN5 LAMA2 SLC40A1

3.83e-05200845e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 HMCN1 LRFN5 LAMA2 LPAR1

3.83e-0520084544317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.83e-05200845cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.83e-05200845cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE HMCN1 LRFN5 LAMA2 LPAR1

3.83e-05200845311fab076f2ceb258e3970eb21e39344b894042a
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 HMCN1 LRFN5 LAMA2 LPAR1

3.83e-052008451c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 HMCN1 LRFN5 LAMA2 LPAR1

3.83e-05200845440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PLEKHG1 HMCN1 LRFN5 LAMA2

3.83e-0520084558b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellLA-10._Endothelium_II|LA / Chamber and Cluster_Paper

PLEKHG1 TLL1 DOCK9 UGT3A2

1.21e-04134844048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 RAPGEF2 ZNF582 OPLAH

1.28e-04136844edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 RAPGEF2 ZNF582 OPLAH

1.28e-0413684403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC7A2 FRMPD2 ASPM PLK4

1.59e-04144844bdd6d00b2d1c9dad989df82367a60e8be79de816
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRHDE CYP1B1 ZNF582 LPAR1

1.68e-0414684486cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRDE2 CENPE FAM20B ASPM

1.68e-0414684445d7cb73776e60d22f335a651845e21e16948fcc
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CENPE ASPM HIGD2B PLK4

1.81e-0414984489faa84af68d4727180f39718964bb3bc65d8fe6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC7A2 LAMA2 MYO1B PLCE1

2.22e-04157844bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PLK4 PLCE1 DNAH11

2.22e-04157844410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 DOCK9 SLC22A10 PRICKLE2

2.38e-04160844958256e3d3836160763b82bb48f794087918d935
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 UGT3A2 PANK1 XPOT

2.38e-04160844c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTX1 DOCK9 SLC41A1 PLCE1

2.44e-04161844133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTX1 DOCK9 SLC41A1 PLCE1

2.44e-041618449466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTX1 DOCK9 SLC41A1 PLCE1

2.44e-04161844cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTX1 DOCK9 SLC41A1 PLCE1

2.50e-0416284496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG1 SLC7A2 ZBTB10 DNAH11

2.62e-04164844eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CENPE ASPM MYEF2

2.68e-041658444297588f809e8a8275ab1a6ed99daac7ad93bd61
ToppCell10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

CYP1B1 CENPE ASPM PLK4

2.80e-0416784482739226347d74897be000f429b73543a031af96
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

CYP1B1 CENPE ASPM PLK4

2.80e-04167844dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CENPE ASPM PLK4

2.80e-04167844bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LAMA2 KCNT1 ADCYAP1R1

2.87e-041688444b2d29a7843bf45922038c093ca7ec0600756adc
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC25A1 UGT3A2 PANK1

2.87e-04168844b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC25A1 UGT3A2 PANK1

2.87e-04168844073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC25A1 UGT3A2 PANK1

2.93e-04169844f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC25A1 UGT3A2 PANK1

2.93e-041698447785cab967a33560830c394c918d6ce625103858
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FANCD2 CENPE ASPM HIGD2B

2.93e-04169844bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 SLC22A10 PLK4 PLCE1

3.00e-04170844f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PRDM8 FRMPD2 LAMA2

3.00e-04170844985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 TRAP1 DOCK9 UGT3A2

3.00e-04170844dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG1 ITGA3 RAPGEF2 DNAH11

3.00e-04170844513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A2 LRFN5 LAMA2 LPAR1

3.07e-04171844972fab891135bd755d5526cbc5a963200067b0a6
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC7A2 CENPE VSTM2A ASPM

3.07e-04171844845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE ASPM LAMA2 PLK4

3.07e-04171844b0373ed8283ee1792b6a490bff93906546978593
DiseaseCakut

TRAP1 CHD1L

5.83e-0413822C1968949
DiseaseNephronophthisis

NPHP1 SLC41A1

5.83e-0413822C0687120
Diseaseascending aortic diameter

PRDM8 HMCN1 LPAR1 PLCE1

6.37e-04140824EFO_0021787
DiseaseMyopia

TRHDE LRFN5 DOCK9 FRMPD2 LAMA2 RAPGEF2

7.21e-04385826HP_0000545
DiseaseAutosomal recessive primary microcephaly

CENPE ASPM

7.82e-0415822cv:C3711387
Diseasetestosterone measurement

SLC17A2 UBE4A NRDE2 POLR1A GTF3C2 HMCN1 CENPE TLL1 SLC22A10 FAM20B ZBTB10

7.89e-0412758211EFO_0004908
Diseasepreeclampsia, hypertension, pregnancy-induced

PRDM8 PLCE1

8.93e-0416822EFO_0000668, MONDO_0024664
DiseaseSeckel syndrome

CENPE PLK4

1.70e-0322822C0265202
DiseasePrimary microcephaly

ASPM PLK4

1.70e-0322822C0431350
DiseaseQRS duration, response to sulfonylurea

LRFN5 DOCK9

1.86e-0323822EFO_0005055, EFO_0007922
Diseaseprostate specific antigen measurement

LAMA2 ATP9B SLC41A1 DNAH11

1.90e-03188824EFO_0004624

Protein segments in the cluster

PeptideGeneStartEntry
ARIFNTFGPRMHMND

UXS1

256

Q8NBZ7
AALIRMLANFMGHSV

TRHDE

531

Q9UKU6
MLANFMGHSVFQRGL

TRHDE

536

Q9UKU6
GMPRNSSRFINRHNM

ALG13

656

Q9NP73
FRMSAQMNRIATHLE

DNAH11

981

Q96DT5
VTMLQRQGFSMRTLF

SLC7A2

466

P52569
MREMHRAATFIQSTF

ASPM

2331

Q8IZT6
FNVSSFVLRAMMSGQ

ABHD8

331

Q96I13
MTFSDGLTLNRTQMH

RARG

286

P13631
RCHFMQSQFLGGTMI

LRFN5

516

Q96NI6
LQVLMGRMESVFNHA

CYFIP1

461

Q7L576
MKTFSSFLQIGRNMH

OR1S1

1

Q8NH92
QHLMGQQALFSRDMS

ITPRID1

886

Q6ZRS4
MHRGLIISTMQAVFS

ATP9B

936

O43861
NNFTDFTNVRMGFHM

HINT3

121

Q9NQE9
MRSHGMTGAQTRFTF

KIAA1109

3006

Q2LD37
ISMFNGQLLFDRPMH

HNRNPM

261

P52272
ELTHPSNMRFMQFRA

KCNT1

901

Q5JUK3
AHIFGYVRQRTMRMS

LPAR1

226

Q92633
MFHMVQSAGVLQTRG

FAT2

2011

Q9NYQ8
MVNHRLQSFFGGTVM

ITGA3

766

P26006
FNHTRAHQVLFMMVL

OR2T8

16

A6NH00
RHNDNIMLRSTGHMF

PIK3C2A

1251

O00443
TGLMHRIQALFENAM

NRDE2

1066

Q9H7Z3
QRIRTLNADLMMFAH

LAMA2

246

P24043
FNHTRAHQVLFMMVL

OR2T33

16

Q8NG76
LQSMHQFRQDTGTMR

DTX1

76

Q86Y01
SFHRGNSQRSQLMMR

HIGD2A

66

Q9BW72
NFIHMNLFVSFMLRA

ADCYAP1R1

186

P41586
TVNDMFIVGSHRYRM

HMCN1

646

Q96RW7
RAFQRRMAGMFQVTF

NPC1L1

601

Q9UHC9
FMRQRSFQESMGHGS

PRICKLE2

726

Q7Z3G6
TRHVNILLFMGFMTR

ARAF

361

P10398
RLMMHTQIAAQGFTI

HIGD2B

76

Q4VC39
HNIRRFMFEMPFTQT

DOCK9

1891

Q9BZ29
HISLEGFTFNMAVRM

FRMPD2

831

Q68DX3
HSRNMQFHGFNQLMR

GUCY2F

381

P51841
SGGHRVLLFSQMTQM

CHD1L

361

Q86WJ1
RAAHSMMRNFFTRQP

CYP1B1

146

Q16678
FTANQRCSMEFHRIM

CENPE

2156

Q02224
RAHGSVFYQIMTMRR

NPHP1

531

O15259
LTRHTFVVFFRVMMA

FANCD2

1226

Q9BXW9
FMGMANIHSIRRSFQ

MTMR3

346

Q13615
AMHRFIQMGSEKNFS

PANK1

316

Q8TE04
TMQAMLHFGGRLAQS

RUSC1

691

Q9BVN2
QYEMARSQTHTQRGM

RSRC2

406

Q7L4I2
HQLPAFANMTMSVRR

RAPGEF6

276

Q8TEU7
MTLNTFHFAGRGEMN

POLR1A

1226

O95602
IMHYARNTFSRGMFL

TLL1

296

O43897
SMFNGQFLFDRPMHV

MYEF2

291

Q9P2K5
HQGLMSFEGFARFLM

PLCE1

1361

Q9P212
NHMGRRISQILFMFL

SLC22A10

401

Q63ZE4
FSHRFMSIAEQMGRI

OPLAH

741

O14841
MGMRSASQFTRDFIR

GPRASP2

621

Q96D09
AAFLLMLRNFLQGHM

NBEAL2

951

Q6ZNJ1
NASFRMTSDLVYHMR

PRDM8

631

Q9NQV8
FAIAMQMFSLAHRPV

MICU2

331

Q8IYU8
AMDTHFANMRSLIQI

SGSM2

876

O43147
VAMGHIMYFRFAQNT

SLC40A1

531

Q9NP59
VQASRISTFLHMNGM

SLC41A1

366

Q8IVJ1
MEAFSRRHFQTLTVM

PRAMEF1

41

O95521
RASFNRMVMHSAASP

PLK4

831

O00444
HQLPAFANMTMSVRR

RAPGEF2

131

Q9Y4G8
NSHARRMQAFEASPM

VSTM2A

151

Q8TAG5
GKAFARSTNLNMHMR

ZNF846

456

Q147U1
VLFHSRFMELTRMQQ

SPEN

1581

Q96T58
LSVNHKARIAMFSMF

OR4E1

21

P0C645
SAANREDQRAFHRMM

FAM20B

31

O75063
LRFLQHQMAMAAAAA

SUPT20H

736

Q8NEM7
GFASQHMLMRSLNTV

EZH1

91

Q92800
ALIMHFSNFTMITQR

SLC17A2

21

O00624
RFGMFEFLSNHMRDA

SLC25A1

101

P53007
FQMQRMTSAFIDHFG

PPP6R1

556

Q9UPN7
IIREFMLASNHMNGS

ZNF582

496

Q96NG8
TVLEMGAARHFLRMQ

TRAP1

611

Q12931
IANDRFINMLLGHMS

XPOT

221

O43592
RMQLESRAHFNAMFQ

GTF3C2

876

Q8WUA4
MSFSEMNRRTLAFRG

ZBTB10

1

Q96DT7
RMTLVSNSHMGLFNQ

PLEKHG1

31

Q9ULL1
LQMFGQLARFHNIMS

UBE4A

836

Q14139
MFFSFCRRQQHMQST

UGT3A2

206

Q3SY77
LVQHMVSAMQRLGFT

TRRAP

1981

Q9Y4A5
MCTRSGNMLGRHFFT

WDFY1

141

Q8IWB7
VMVLGNSHLFMNRSN

GTF2H3

41

Q13889
LMFRVGNLRNSHMVS

KCNJ3

211

P48549
FRTVRNAMQIVGFMD

MYO1B

251

O43795