Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM3 ACSM2A ACSM2B

8.93e-0681103GO:0004321
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

ACSM3 ACSM2A ACSM2B

2.60e-05111103GO:0031956
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

8.99e-0531102GO:0018858
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

1.79e-0441102GO:0102391
GeneOntologyMolecularFunctionC-acyltransferase activity

ACSM3 ACSM2A ACSM2B

2.01e-04211103GO:0016408
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSM3 ACSM2A ACSM2B

3.86e-04261103GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSM3 ACSM2A ACSM2B

4.32e-04271103GO:0016405
GeneOntologyMolecularFunctionacid-thiol ligase activity

ACSM3 ACSM2A ACSM2B

6.53e-04311103GO:0016878
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

PCLO RIMS1

8.24e-0481102GO:0098882
DomainFN3

EPHB4 COL6A3 COL7A1 FN1 VASN IGDCC4 PTPRS TNXB

9.12e-061851048SM00060
DomainFN3

EPHB4 COL6A3 COL7A1 FN1 VASN IGDCC4 PTPRS TNXB

1.55e-051991048PS50853
DomainFN3_dom

EPHB4 COL6A3 COL7A1 FN1 VASN IGDCC4 PTPRS TNXB

2.21e-052091048IPR003961
Domainfn3

EPHB4 COL7A1 FN1 VASN IGDCC4 PTPRS TNXB

3.40e-051621047PF00041
DomainEGF-like_CS

EPHB4 HSPG2 FN1 VASN ADAM29 CELSR2 CNTNAP2 TNXB

1.06e-042611048IPR013032
DomainAMP-bd_C

ACSM3 ACSM2A ACSM2B

1.08e-04171043IPR025110
DomainAMP-binding_C

ACSM3 ACSM2A ACSM2B

1.08e-04171043PF13193
Domain-

IGSF8 EPHB4 HSPG2 COL6A3 COL7A1 FN1 TAPBPL VASN DAG1 IGDCC4 PTPRS TNXB

3.17e-04663104122.60.40.10
DomainAMP-binding_CS

ACSM3 ACSM2A ACSM2B

3.97e-04261043IPR020845
DomainMCM_N

MCM5 MCM7

4.54e-0461042PF14551
DomainMCM_CS

MCM5 MCM7

4.54e-0461042IPR018525
DomainMCM_N

MCM5 MCM7

4.54e-0461042IPR027925
DomainCadherin-like

PCDHB2 DAG1 PCDH17 CELSR2 PCDH7

4.78e-041161045IPR015919
DomainAMP_BINDING

ACSM3 ACSM2A ACSM2B

4.97e-04281043PS00455
DomainIg-like_fold

IGSF8 EPHB4 HSPG2 COL6A3 COL7A1 FN1 TAPBPL VASN DAG1 IGDCC4 PTPRS TNXB

5.57e-0470610412IPR013783
DomainEGF_1

HSPG2 FN1 VASN ADAM29 CELSR2 CNTNAP2 TNXB

5.62e-042551047PS00022
DomainAMP-binding

ACSM3 ACSM2A ACSM2B

6.10e-04301043PF00501
DomainAMP-dep_Synth/Lig

ACSM3 ACSM2A ACSM2B

6.10e-04301043IPR000873
DomainEGF

HSPG2 VASN CELSR2 CNTNAP2 TNXB

6.96e-041261045PF00008
DomainEGF_2

EPHB4 HSPG2 VASN ADAM29 CELSR2 CNTNAP2 TNXB

7.05e-042651047PS01186
DomainMCM_OB

MCM5 MCM7

8.41e-0481042PF17207
DomainMCM_OB

MCM5 MCM7

8.41e-0481042IPR033762
DomainMCM_2

MCM5 MCM7

8.41e-0481042PS50051
DomainMCM_1

MCM5 MCM7

8.41e-0481042PS00847
DomainMFS_1

SPNS1 SLC43A1 SLC16A5 SLC17A8

8.99e-04771044PF07690
DomainMFS

SPNS1 SLC43A1 SLC16A5 SLC17A8

8.99e-04771044IPR011701
DomainMCM

MCM5 MCM7

1.08e-0391042SM00350
DomainMCM_dom

MCM5 MCM7

1.08e-0391042IPR001208
DomainMCM

MCM5 MCM7

1.08e-0391042IPR031327
DomainMCM

MCM5 MCM7

1.08e-0391042PF00493
DomainLAM_G_DOMAIN

HSPG2 CELSR2 CNTNAP2

1.23e-03381043PS50025
DomainLaminin_G_2

HSPG2 CELSR2 CNTNAP2

1.43e-03401043PF02210
DomainLamG

HSPG2 CELSR2 CNTNAP2

1.88e-03441043SM00282
DomainEGF_3

HSPG2 VASN ADAM29 CELSR2 CNTNAP2 TNXB

2.03e-032351046PS50026
DomainuDENN

DENND1A MADD

2.68e-03141042SM00800
DomainEGF-like_dom

HSPG2 VASN ADAM29 CELSR2 CNTNAP2 TNXB

2.70e-032491046IPR000742
DomainuDENN

DENND1A MADD

3.08e-03151042PF03456
DomainCadherin_CS

PCDHB2 PCDH17 CELSR2 PCDH7

3.23e-031091044IPR020894
DomainDENN

DENND1A MADD

3.50e-03161042SM00799
DomainDENN

DENND1A MADD

3.50e-03161042PF02141
DomaindDENN

DENND1A MADD

3.50e-03161042PF03455
DomainUDENN

DENND1A MADD

3.50e-03161042PS50946
DomainDDENN

DENND1A MADD

3.50e-03161042PS50947
DomaindDENN

DENND1A MADD

3.50e-03161042SM00801
DomaindDENN_dom

DENND1A MADD

3.50e-03161042IPR005112
DomainuDENN_dom

DENND1A MADD

3.50e-03161042IPR005113
DomainDENN

DENND1A MADD

3.50e-03161042PS50211
DomainDENN_dom

DENND1A MADD

3.50e-03161042IPR001194
DomainCADHERIN_1

PCDHB2 PCDH17 CELSR2 PCDH7

3.67e-031131044PS00232
DomainCadherin

PCDHB2 PCDH17 CELSR2 PCDH7

3.67e-031131044PF00028
DomainCADHERIN_2

PCDHB2 PCDH17 CELSR2 PCDH7

3.79e-031141044PS50268
Domain-

PCDHB2 PCDH17 CELSR2 PCDH7

3.79e-0311410442.60.40.60
DomainCA

PCDHB2 PCDH17 CELSR2 PCDH7

3.91e-031151044SM00112
DomainLaminin_G

HSPG2 CELSR2 CNTNAP2

4.14e-03581043IPR001791
DomainCadherin

PCDHB2 PCDH17 CELSR2 PCDH7

4.28e-031181044IPR002126
Domain-

COL6A3 COL7A1

4.43e-031810424.10.410.10
DomainPrtase_inh_Kunz-CS

COL6A3 COL7A1

4.43e-03181042IPR020901
DomainBPTI_KUNITZ_1

COL6A3 COL7A1

4.94e-03191042PS00280
DomainBPTI_KUNITZ_2

COL6A3 COL7A1

4.94e-03191042PS50279
DomainKunitz_BPTI

COL6A3 COL7A1

4.94e-03191042PF00014
PathwayREACTOME_ECM_PROTEOGLYCANS

HSPG2 COL6A3 FN1 DAG1 PTPRS TNXB

5.46e-0676836M27219
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 HSPG2 SETD1B MCM5 ANKLE1 KAT2A MED13L DENND1A MADD TAOK2 CELSR2 SLC16A5 ARVCF PTPRS PLEKHO2 MTHFR EIF4G1 PALM SNAPC4

2.55e-0911051121935748872
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZC3H14 NOL6 PUM2 MCM5 KAT2A MORC2 KANK2 ALKBH5 DENND1A MFF TAOK2 MDC1 EIF4G1 PWP2 MIOS PALM3 MACF1 YME1L1 USP6NL MAN1B1

6.24e-0814971122031527615
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

ZC3H14 TBC1D15 TNFSF14 NOL6 SMC6 NASP MORC2 TRIM24 KANK2 PNPT1 MDC1 SYNE2 EIF4G1 YME1L1

1.52e-077541121435906200
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

IGSF8 EPHB4 TAPBPL NHSL2 MADD ACSM3 PLEKHO2 CSNK1G3 OASL PALM MACF1 NBR1 USP6NL

5.89e-077191121335337019
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPHB4 NR2C2 SPNS1 TBC1D15 VARS2 TRIM24 KANK2 TUBGCP6 PNPT1 GLS SYNE2 PWP2 PALM MACF1 YME1L1 PCDH7 NBR1 USP6NL

1.28e-0614871121833957083
Pubmed

Mice develop normally without tenascin.

HSPG2 FN1 TNXB

1.80e-06811231383086
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 COL6A3 COL7A1 FN1 TNXB

2.07e-0664112522261194
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

PUM2 MADD TAOK2 AP2M1 CNTNAP2 MACF1

4.20e-06130112612421765
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

ZC3H14 PUM2 MCM5 MCM7 KANK2 CRYAB EIF4G1 MACF1

8.71e-06315112826777405
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 FN1 NOL6 MCM5 PNPT1 MDC1 SYNE2 EIF4G1 PWP2 OASL MACF1

8.88e-066531121122586326
Pubmed

Timeless links replication termination to mitotic kinase activation.

SMC6 MCM5 MCM7

9.08e-0613112321573113
Pubmed

Type VII collagen specifically binds fibronectin via a unique subdomain within the collagenous triple helix.

COL7A1 FN1

1.03e-05211227963647
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

1.03e-052112219634011
Pubmed

Expression, nuclear localization and interactions of human MCM/P1 proteins.

MCM5 MCM7

1.03e-05211229223437
Pubmed

Differential deposition of basement membrane components during formation of the caudal neural tube in the mouse embryo.

HSPG2 FN1

1.03e-05211223665768
Pubmed

Genome-wide analyses of human perisylvian cerebral cortical patterning.

PCDH17 CNTNAP2

1.03e-052112217978184
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

1.03e-052112216521160
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

1.03e-052112229948332
Pubmed

Deletion of astroglial connexins weakens the blood-brain barrier.

HSPG2 FN1 DAG1

1.15e-0514112322472609
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

VGF NHSL2 KANK2 TAOK2 CELSR2 ARVCF PTPRS SYNE2 EIF4G1 MIOS MACF1 RIMS1 TACC3

1.41e-059631121328671696
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IGSF8 FN1 PCLO KANK2 MADD CRYAB MLXIPL AP2M1 NWD2 ARVCF PTPRS EIF4G1 MIOS PALM MACF1 RIMS1

1.43e-0514311121637142655
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

CAMK1D VASN DAG1 KANK2 ARVCF PLEKHO2 EIF4G1 PALM3 MACF1 USP6NL

1.52e-055651121025468996
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NHSL2 PCLO NOL6 MCM5 KAT2A NEB AP2M1 ACSM3 GLS SYNE2 EIF4G1 PWP2 PALM MACF1 RIMS1 CFAP46

1.57e-0514421121635575683
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

HSPG2 COL6A3 FN1 DAG1 TNXB

1.61e-0597112527559042
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

HSPG2 FN1 DAG1

1.77e-0516112317948866
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MORC2 TAOK2 TTBK2 GLS CNTNAP2

1.87e-05100112510048485
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

ZC3H14 TBC1D15 MORC2 KANK2 MFF TAB3 MADD AP2M1 YME1L1 NBR1

2.68e-056041121038803224
Pubmed

The minichromosome maintenance proteins 2-7 (MCM2-7) are necessary for RNA polymerase II (Pol II)-mediated transcription.

MCM5 MCM7

3.08e-053112219318354
Pubmed

The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids.

MCM5 MCM7

3.08e-053112234449552
Pubmed

Immunohistochemical localization of syndecan-1 in the dental follicle of postnatal mouse teeth.

HSPG2 FN1

3.08e-053112217608588
Pubmed

Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.

HSPG2 FN1

3.08e-053112219553700
Pubmed

Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function.

HSPG2 DAG1

3.08e-053112216098969
Pubmed

Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells.

MCM5 MCM7

3.08e-053112235490917
Pubmed

Reciprocal expressions between α-dystroglycan and integrin β1, perlecan receptors, in the murine enamel organ development.

HSPG2 DAG1

3.08e-053112223722005
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

FN1 TNXB

3.08e-05311227687262
Pubmed

Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung.

AP2M1 EIF4G1

3.08e-053112217290396
Pubmed

Differential expression profiles between α-dystroglycan and integrin β1 in ameloblastoma: two possible perlecan signalling pathways for cellular growth and differentiation.

HSPG2 DAG1

3.08e-053112221255062
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

ZC3H14 KAT2A MORC2 ALKBH5 PWP2 MIOS MACF1

3.67e-05281112724163370
Pubmed

Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways.

FN1 EIF4G1

6.14e-054112215961545
Pubmed

Minichromosome maintenance (MCM) and AgNOR proteins expression in desmoid tumours: a tissue microarray analysis.

MCM5 MCM7

6.14e-054112221478101
Pubmed

MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.

NR2C2 TAB3

6.14e-054112224565101
Pubmed

Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis.

COL7A1 DAG1

6.14e-05411227774920
Pubmed

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins.

MCM5 MCM7

6.14e-05411228265339
Pubmed

PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India.

PNPT1 PTPRQ

6.14e-054112234374074
Pubmed

Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication.

MCM5 MCM7

6.14e-054112219377303
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

6.14e-054112232830538
Pubmed

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

HSPG2 DAG1

6.14e-054112225646087
Pubmed

Deficiency of tenascin-X causes a decrease in the level of expression of type VI collagen.

COL6A3 TNXB

6.14e-054112215194424
Pubmed

Minichromosome Maintenance Proteins MCM-3, MCM-5, MCM-7, and Ki-67 as Proliferative Markers in Adrenocortical Tumors.

MCM5 MCM7

6.14e-054112230842144
Pubmed

Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.

MLXIPL ACSM3 CELSR2 ACSM2B

6.30e-0566112420679960
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DAG1 CELSR2 ARVCF CSNK1G3 PALM MACF1 PCDH7 USP6NL

6.85e-05421112836976175
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

HSPG2 FN1 NEB PLEKHO2 PWP2 PCDH7

7.04e-05214112622199357
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

HSPG2 COL6A3 COL7A1 FN1 TNXB

7.87e-05135112528675934
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

TMEM202 TBC1D15 SETD1B PUM2 KAT2A MED13L GLS SLC17A8

8.06e-05431112833660365
Pubmed

Report and abstracts of the Fourth International Workshop on Human Chromosome 2 Mapping 1996.

COL6A3 FN1 NEB GLS

8.38e-057111248751373
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

FN1 NASP NEB TRIM24 MFF SYNE2 MACF1

8.62e-05322112726514267
Pubmed

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.

KIF24 TTBK2

1.02e-045112230375385
Pubmed

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

MCM5 MCM7

1.02e-045112223405012
Pubmed

Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells.

HSPG2 FN1

1.02e-04511229915576
Pubmed

Disruption of the talin gene arrests mouse development at the gastrulation stage.

HSPG2 FN1

1.02e-045112211084655
Pubmed

TAB3 upregulates PIM1 expression by directly activating the TAK1-STAT3 complex to promote colorectal cancer growth.

NR2C2 TAB3

1.02e-045112232229191
Pubmed

Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.

HSPG2 FN1

1.02e-045112211493006
Pubmed

Molecular architecture of the human GINS complex.

MCM5 MCM7

1.02e-045112217557111
Pubmed

Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin.

COL7A1 FN1

1.02e-04511229169408
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

HSPG2 COL7A1 FN1

1.12e-0429112322613833
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

HSPG2 COL6A3 FN1 DAG1 TNXB

1.14e-04146112527068509
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHB2 PCDH17 CELSR2 PCDH7

1.15e-0477112410835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHB2 PCDH17 CELSR2 PCDH7

1.33e-0480112410716726
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

HSPG2 COL6A3 COL7A1 FN1 TNXB

1.42e-04153112525037231
Pubmed

Human Mcm proteins at a replication origin during the G1 to S phase transition.

MCM5 MCM7

1.53e-046112212364596
Pubmed

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

PCLO RIMS1

1.53e-046112219812333
Pubmed

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

HSPG2 FN1

1.53e-046112211956183
Pubmed

The IA-2 interactome.

MADD PTPRS

1.53e-046112216273344
Pubmed

Pairwise interactions of the six human MCM protein subunits.

MCM5 MCM7

1.53e-046112215236977
Pubmed

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.

MCM5 MCM7

1.53e-046112221220507
Pubmed

A role for USP7 in DNA replication.

MCM5 MCM7

1.53e-046112224190967
Pubmed

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.

PCLO RIMS1

1.53e-046112214734538
Pubmed

The eukaryotic Mcm2-7 replicative helicase.

MCM5 MCM7

1.53e-046112222918583
Pubmed

In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP.

MCM5 MCM7

1.53e-04611229099751
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

HSPG2 COL6A3 FN1 TNXB

1.77e-0486112428327460
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

MADD MLXIPL CELSR2

1.81e-0434112319060911
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

HSPG2 COL6A3 FN1 VASN PTPRS TNXB

1.91e-04257112616335952
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TBC1D15 PCLO NOL6 SMC6 NASP MCM5 MCM7 RIC8B AP2M1 MDC1 GLS EIF4G1 PWP2 NBR1

1.99e-0414251121430948266
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NASP PUM2 MORC2 TUBGCP6 MDC1 EIF4G1 RIMS1 TACC3 SNAPC4 PCDH7

2.07e-047741121015302935
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

HSPG2 COL6A3 FN1 NEB CRYAB SYNE2 MACF1 ZNF417

2.13e-04497112823414517
Pubmed

O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions.

MCM5 MCM7

2.14e-047112230069701
Pubmed

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation.

NR2C2 TAB3

2.14e-047112222158122
Pubmed

Identification and characterization of a novel component of the human minichromosome maintenance complex.

MCM5 MCM7

2.14e-047112217296731
Pubmed

Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17.

MCM5 MCM7

2.14e-047112219150984
Pubmed

alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.

COL7A1 FN1

2.14e-04711229151677
Pubmed

Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma.

MCM5 MCM7

2.14e-047112211248027
Pubmed

The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.

KAT2A TACC3

2.14e-047112214767476
Pubmed

Interaction of chromatin-associated Plk1 and Mcm7.

MCM5 MCM7

2.14e-047112215654075
Pubmed

Binding of human minichromosome maintenance proteins with histone H3.

MCM5 MCM7

2.14e-04711228798650
Pubmed

Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice.

HSPG2 FN1

2.14e-047112212242711
Pubmed

Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.

MCM5 MCM7

2.14e-047112223764002
Pubmed

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.

HSPG2 DAG1

2.14e-047112211802174
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NOL6 NAP1L3 NEB TRIM24 TTBK2 ARVCF GLS SYNE2 YME1L1

2.29e-04638112931182584
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZC3H14 NR2C2 MCM5 MCM7 KAT2A MED13L MORC2 TRIM24 ALKBH5 E2F8 AP2M1 RASGRP2

2.34e-0411031121234189442
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

TBC1D15 MFF MADD SYNE2 TMED8 MIOS YME1L1 PCDH7

2.35e-04504112834432599
InteractionCDH16 interactions

DAG1 TRIM24 CRYAB CELSR2 PTPRS

4.11e-07281115int:CDH16
InteractionACSM2A interactions

ACSM3 ACSM2A ACSM2B

6.48e-0741113int:ACSM2A
InteractionRHOC interactions

EPHB4 ZC3H14 VASN NOL6 DAG1 CCDC187 MFF PCDH17 AP2M1 PTPRS CSNK1G3 SYNE2 PALM MACF1 PCDH7

7.46e-0758411115int:RHOC
InteractionPCDH12 interactions

PCDH17 CELSR2 PTPRS PCDH7

5.91e-06221114int:PCDH12
InteractionTMEM30B interactions

IGSF8 PCDH17 IGDCC4 CELSR2 PTPRS PCDH7

7.48e-06851116int:TMEM30B
InteractionH4C2 interactions

FN1 NASP MCM7 TRIM24 RLIM

1.18e-05541115int:H4C2
InteractionH4C13 interactions

FN1 NASP MCM7 TRIM24 RLIM

1.68e-05581115int:H4C13
InteractionRAC2 interactions

EPHB4 NR2C2 VASN NOL6 DAG1 KANK2 MFF PCDH17 CSNK1G3 SYNE2 PALM MACF1 PCDH7 USP6NL

2.02e-0567411114int:RAC2
InteractionRYK interactions

EPHB4 PCDHB2 DAG1 PCDH17 IGDCC4 CELSR2 PTPRS PCDH7

2.29e-052121118int:RYK
InteractionRHOU interactions

EPHB4 VASN NOL6 MCM5 PCDH17 PTPRS CSNK1G3 GLS PALM MACF1 PCDH7 USP6NL

2.47e-0551011112int:RHOU
InteractionNXPH2 interactions

VGF MADD CELSR2 PCDH7

3.15e-05331114int:NXPH2
InteractionH4C6 interactions

FN1 NASP MCM7 TRIM24 RLIM

3.93e-05691115int:H4C6
InteractionTOP3B interactions

EPHB4 HSPG2 SETD1B MCM5 ANKLE1 KAT2A MED13L KANK2 DENND1A MADD TAOK2 CELSR2 SLC16A5 ARVCF PTPRS PLEKHO2 MTHFR MDC1 EIF4G1 PALM SNAPC4

4.64e-05147011121int:TOP3B
InteractionH3C10 interactions

NASP MCM7 TRIM24 RLIM

5.57e-05381114int:H3C10
InteractionRHOB interactions

EPHB4 VASN NOL6 DAG1 KANK2 PCDH17 AP2M1 ARVCF PTPRS PLEKHO2 CSNK1G3 PALM MACF1 PCDH7 USP6NL

5.73e-0584011115int:RHOB
InteractionLHX3 interactions

NR2C2 TRIM24 KANK2 ZNF587 SYNE2 RLIM ZNF417

7.45e-051851117int:LHX3
InteractionCDH1 interactions

CAMK1D VASN DAG1 KANK2 CRYAB AP2M1 ARVCF PTPRS PLEKHO2 PTPRQ EIF4G1 PALM3 MACF1 USP6NL

8.30e-0576811114int:CDH1
InteractionBBS7 interactions

KANK2 MADD PLEKHO2 PWP2 MIOS

1.07e-04851115int:BBS7
InteractionFLRT1 interactions

VASN PCDH17 CELSR2 PCDH7

1.19e-04461114int:FLRT1
InteractionRHOH interactions

EPHB4 SPNS1 VASN DAG1 KANK2 MFF PCDH17 AP2M1 PTPRS PCDH7 USP6NL

1.23e-0451211111int:RHOH
InteractionH3C1 interactions

NR2C2 SETD1B NOL6 SMC6 NASP MCM5 MCM7 KAT2A NEB MORC2 TRIM24 TMEM132D MDC1 RLIM EIF4G1

1.25e-0490111115int:H3C1
InteractionH3C4 interactions

NASP TRIM24 RLIM

1.48e-04191113int:H3C4
InteractionRAC3 interactions

EPHB4 VASN DAG1 MFF PCDH17 AP2M1 PTPRS CSNK1G3 PALM MACF1 PCDH7 USP6NL

1.57e-0461911112int:RAC3
InteractionRND2 interactions

EPHB4 VASN NOL6 MFF PCDH17 PTPRS CSNK1G3 SYNE2 PCDH7 USP6NL

1.61e-0444011110int:RND2
InteractionH4C3 interactions

FN1 NASP TRIM24 RLIM

1.65e-04501114int:H4C3
InteractionRHOQ interactions

EPHB4 VASN DAG1 PCDH17 PTPRS CSNK1G3 PALM ZNF417 PCDH7 USP6NL

1.67e-0444211110int:RHOQ
InteractionACSM2B interactions

ACSM2A ACSM2B

1.79e-0441112int:ACSM2B
GeneFamilyFibronectin type III domain containing

EPHB4 COL7A1 FN1 IGDCC4 PTPRS PTPRQ TNXB

4.08e-06160747555
GeneFamilyAcyl-CoA synthetase family

ACSM3 ACSM2A ACSM2B

1.60e-042674340
GeneFamilyMCM family

MCM5 MCM7

5.84e-0497421085
GeneFamilyNon-clustered protocadherins

PCDH17 PCDH7

1.06e-031274221
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRS PTPRQ

3.30e-0321742813
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 COL6A3 FN1 NHSL2 DCLRE1B KANK2 TAOK2 ZNF417 TNXB

4.38e-1016611399d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNFSF14 TAPBPL KANK2 KIF24 TUBGCP6 SLC16A5 MACF1 YME1L1

3.32e-081921138930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNFSF14 TAPBPL KANK2 KIF24 TUBGCP6 SLC16A5 MACF1 YME1L1

3.32e-081921138c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP18 NEB DENND1A PNPT1 MLXIPL OASL SLC17A8

1.25e-07152113718194f757d319958f26e5a91f56d89f25711236f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A3 FN1 NHSL2 PTPRS MACF1 PCDH7 TNXB

6.31e-07193113799525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNFSF14 TAPBPL KIF24 TUBGCP6 SLC16A5 MACF1 YME1L1

6.53e-0719411373211d89440a6f4a9b3d4cfb755890816944242ec
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN CRYAB PTPRS MACF1 TNXB

6.99e-0719611379737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN CRYAB PTPRS MACF1 TNXB

6.99e-071961137cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN CRYAB PTPRS MACF1 TNXB

7.24e-07197113794a9603cbd3516fbcce871909693b88f20d41713
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL6A3 FN1 VASN KANK2 CRYAB PALM TNXB

8.01e-0720011372022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL6A3 FN1 VASN KANK2 CRYAB PALM TNXB

8.01e-07200113769b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 FN1 VASN KANK2 CRYAB PCDH7 TNXB

8.01e-0720011375a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAPBPL SLC43A1 NASP MDC1 USP6NL RASGRP2

3.16e-0615811361d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 NAP1L3 PERM1 KANK2 PTPRQ CNTNAP2

4.20e-0616611361f39c7507ac6881aa1a30f8be22f98a1837d926b
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCLO PERM1 ADAM29 NEB MLXIPL TMEM132D

4.98e-061711136fa5cc720bd0045d0307439be547b41d56def5b43
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MCM5 MCM7 ANKLE1 E2F8 TACC3

6.07e-0617711368a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 KANK2 PTPRS RIMS1 PCDH7 TNXB

6.48e-06179113602c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM5 MCM7 ANKLE1 KIF24 E2F8 TACC3

7.35e-06183113642dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 FN1 VASN PALM TNXB ACSM2B

8.06e-061861136a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

COL6A3 FN1 NHSL2 PTPRS MACF1 TNXB

8.31e-06187113692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

USP18 FN1 PNPT1 OASL CNTNAP2 USP6NL

8.31e-06187113672e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 KANK2 CRYAB ACSM3 RIMS1 PCDH7

8.57e-061881136293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 VASN IGDCC4 PTPRS PALM TNXB

8.83e-061891136d531399749409d614adca13d181830c6e3287508
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHB4 MCM7 KANK2 KIF24 E2F8 CNTNAP2

9.10e-0619011367be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A3 NHSL2 PTPRS MACF1 PCDH7 TNXB

9.38e-0619111366688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A3 NHSL2 PTPRS MACF1 PCDH7 TNXB

9.66e-06192113699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

COL6A3 TNFSF14 IGDCC4 PTPRS PALM TNXB

9.66e-061921136d21f0f577156f17c899b08871046a26b88aea011
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

MED13L DENND1A SYNE2 MACF1 ACSM2A ACSM2B

9.66e-061921136e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEB MADD TAOK2 MLXIPL EIF4G1

9.95e-061931136471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 FN1 VASN CRYAB TNXB

9.95e-061931136428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A3 NHSL2 PTPRS MACF1 PCDH7 TNXB

9.95e-061931136b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEB MADD TAOK2 MLXIPL EIF4G1

9.95e-061931136fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 FN1 VASN CRYAB TNXB

9.95e-061931136eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

COL6A3 FN1 NHSL2 PTPRS CNTNAP2 PCDH7

9.95e-061931136acad568621ed677031797b8c2e34dafea798d681
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHB4 MCM7 KANK2 E2F8 CNTNAP2 TACC3

9.95e-061931136b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.02e-0519411368fae8061b350336299aa81f378e07deadbd55123
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.02e-0519411364d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.06e-051951136df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.06e-0519511364243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.09e-05196113642e9828222a9663525d571633e8a454c30bfa7f8
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.09e-051961136bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NASP MCM5 MCM7 ANKLE1 E2F8 TACC3

1.09e-0519611365ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.12e-05197113616758f181ef07c60aee63072e1da9572c5c85414
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 VASN KANK2 CRYAB PALM TNXB

1.12e-051971136c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.12e-05197113613896ec65ccda0b928c91d41112dc01b480036b7
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

HSPG2 KIF24 E2F8 ZNF587 RLIM TACC3

1.12e-051971136038fd92750257d43d5e980fd06d77742b543f11a
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DMGDH CRYAB ACSM3 PALM ACSM2A ACSM2B

1.15e-05198113652e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 DAG1 IGDCC4 CRYAB TNXB

1.15e-0519811365e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 FN1 VASN CRYAB TNXB

1.15e-0519811361b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DMGDH CRYAB ACSM3 PALM ACSM2A ACSM2B

1.15e-051981136eeec789d226171f30799577cc37c07bdced2e3cb
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HSPG2 COL6A3 FN1 KANK2 CRYAB PTPRS

1.18e-05199113640de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

USP18 DAG1 NEB IGDCC4 CRYAB PCDH7

1.18e-051991136e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL6A3 FN1 KANK2 CRYAB ACSM3 TNXB

1.18e-051991136e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 HSPG2 FN1 NHSL2 PCDH17 TNXB

1.18e-051991136da5a88749d859d535daa030d0974485906cc0ba7
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.18e-051991136b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.18e-051991136f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 FN1 CRYAB PTPRS MACF1 TNXB

1.18e-0519911369c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell(2)_Fibroblasts-(24)_Fibro-5|World / Cell class and subclass of bone marrow stroma cells in homeostatis

COL6A3 CAMK1D FN1 KANK2 CRYAB TNXB

1.18e-0519911366c0354f57883330c685a8d9d5d3014ace7eca584
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

USP18 DAG1 NEB IGDCC4 CRYAB PCDH7

1.18e-051991136801887db51ac5dc5b068808ff75e3a46643398e9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

NASP MCM5 MCM7 E2F8 SYNE2 TACC3

1.22e-0520011368f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

NASP MCM5 MCM7 E2F8 SYNE2 TACC3

1.22e-052001136a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 FN1 VASN CRYAB PTPRS MACF1

1.22e-052001136c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell390C-Fibroblasts-Fibroblast-H-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 FN1 VASN KANK2 CRYAB PTPRS

1.22e-052001136ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCell343B-Fibroblasts|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-052001136376c1a77031e090be96948b47c78ac0d393f5775
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-052001136db6281b5d4032116310db379d9175d790994c99c
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.22e-052001136389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.22e-052001136e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell(5)_Fibroblasts|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-05200113622c839f27d3abdf86bfabdfa305f205dd899a9dc
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 FN1 VASN CRYAB PTPRS MACF1

1.22e-052001136cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCellParenchymal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-052001136f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 FN1 VASN CRYAB PTPRS MACF1

1.22e-0520011365c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellParenchyma_Control_(B.)-Stromal-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

COL6A3 VASN KANK2 CRYAB PALM TNXB

1.22e-0520011360a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.22e-052001136cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellTracheal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-052001136f74b9b0e27afedd589e828d30194e8417029817a
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A3 VASN KANK2 CRYAB PALM TNXB

1.22e-0520011363fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 VASN KANK2 CRYAB PALM TNXB

1.22e-05200113674ad0ae592252060ee294d7483327d765a6ba1dd
ToppCelltumor_Lung-Fibroblasts|tumor_Lung / Location, Cell class and cell subclass

COL6A3 FN1 VASN KANK2 CRYAB TNXB

1.22e-052001136073a68b5ce232203ffee86342cba2a00d907e119
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

DAG1 DCLRE1B E2F8 TUBGCP6 TACC3 MAN1B1

1.22e-0520011366e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.22e-052001136311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 FN1 NHSL2 PTPRS PCDH7 TNXB

1.22e-05200113634f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellLung_Parenchyma-Control-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A3 VASN KANK2 CRYAB PALM TNXB

1.22e-0520011361e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCell390C-Fibroblasts-Fibroblast-H|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 FN1 VASN KANK2 CRYAB PTPRS

1.22e-052001136671e731977c58a0c44c36b56422085d93d999aad
ToppCellTracheal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 VASN KANK2 CRYAB PALM TNXB

1.22e-0520011367ba292c30d915e66ebc8026fa76492cedf64700e
ToppCellnormal_Lung-Fibroblasts-COL14A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

COL6A3 VASN CRYAB PTPRS PALM TNXB

1.22e-052001136ee3d06865a6300e1279edf6664320b71647f5efb
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

DAG1 DCLRE1B E2F8 TUBGCP6 TACC3 MAN1B1

1.22e-0520011369769185abae084ffac36420c749625e679b70ca8
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

USP18 TNFRSF10D PNPT1 OASL CNTNAP2

4.45e-051531135859de35b24c5d7d73be1c213b90b43362ee2e0eb
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

COL6A3 FN1 NHSL2 PTPRS TNXB

5.34e-0515911353f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 HSPG2 FN1 NHSL2 ACSM2A

5.50e-05160113533050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 FN1 MED13L CNTNAP2 MACF1

6.01e-051631135f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellControl-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

FN1 THSD8 MED13L MLXIPL OASL

7.33e-0517011359e328e1f904c77dcce8aee4df775d7f0ac725775
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 NASP MCM5 MCM7 MACF1

7.33e-051701135e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A1 MCM5 ANKLE1 E2F8 TACC3

7.54e-051711135ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCM7 FAM170A TAB3 PWP2 TACC3

7.54e-051711135f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A1 MCM5 ANKLE1 E2F8 TACC3

7.75e-05172113595219814e37259e34be053572cc95d4639360c27
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MCM7 ANKLE1 KIF24 E2F8

7.75e-0517211352b6cd84c946b1e800caba452ae70145ea285fec1
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCM5 MCM7 ANKLE1 E2F8 TACC3

7.96e-051731135c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM5 MCM7 ANKLE1 E2F8 TACC3

7.96e-05173113531784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MCM5 E2F8 PCDH17 TACC3

8.18e-051741135c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL7A1 FN1 VASN KANK2 MADD

8.18e-051741135fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MCM5 MCM7 E2F8 PCDH17

8.18e-05174113566555c610251ea04f968c258e312d720c18e7cde
DrugLt 3

FN1 TMEM132D MTHFR

3.89e-0671113CID000217025
DrugAmprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

PCLO DAG1 ADAM29 TAOK2 PTPRS MTHFR CNTNAP2 RASGRP2

5.41e-0619611184825_UP
DiseaseX-21319 measurement

ACSM2A ACSM2B

1.35e-0521092EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

4.05e-0531092EFO_0021242
Diseasedextro-looped transposition of the great arteries (is_implicated_in)

MED13L MTHFR

4.05e-0531092DOID:0060770 (is_implicated_in)
Diseasecholesterol to total lipids in large HDL percentage

DMGDH MADD MLXIPL CELSR2

5.20e-05551094EFO_0022234
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

DMGDH MLXIPL CELSR2 SYNE2 MACF1

8.87e-051211095EFO_0008595, EFO_0020943
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

DMGDH MLXIPL CELSR2 SYNE2 MACF1

1.11e-041271095EFO_0008595, EFO_0020947
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

1.34e-0451092EFO_0800378
Diseasefree cholesterol to total lipids in large LDL percentage

DMGDH MLXIPL CELSR2 MACF1

1.66e-04741094EFO_0022280
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

MADD MLXIPL CELSR2 SYNE2 MACF1

2.01e-041441095EFO_0004611, EFO_0020943
DiseaseCongenital muscular dystrophy (disorder)

DAG1 SYNE2

2.01e-0461092C0699743
Diseaseindoleacetylglutamine measurement

ACSM3 ACSM2A

2.01e-0461092EFO_0800035
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

2.01e-0461092EFO_0800106
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

DMGDH MLXIPL CELSR2 SYNE2 MACF1

2.43e-041501095EFO_0004611, EFO_0020947
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

ZC3H14 CNTNAP2

3.73e-0481092DOID:0060308 (implicated_via_orthology)
DiseaseX-17676 measurement

ACSM3 ACSM2B

3.73e-0481092EFO_0800785
Diseasetriglycerides in large LDL measurement

MLXIPL CELSR2 SYNE2

5.43e-04431093EFO_0022319
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DMGDH MLXIPL CELSR2 SYNE2 MACF1

8.99e-042001095EFO_0004611, EFO_0020945
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

PNPT1 PTPRQ

1.03e-03131092C1846647
DiseaseSmall cell carcinoma of lung

TTBK2 TMEM132D CNTNAP2

1.06e-03541093C0149925
Diseasetriglycerides in LDL measurement

MLXIPL CELSR2 SYNE2

1.18e-03561093EFO_0022320
Diseasebeta-hydroxyisovalerate measurement

ACSM3 ACSM2B

1.20e-03141092EFO_0800125
Disease5-methyluridine (ribothymidine) measurement

PCLO PTPRS

1.20e-03141092EFO_0020013
Diseasetriglycerides to total lipids in small VLDL percentage

DMGDH MLXIPL CELSR2

1.31e-03581093EFO_0022338
Diseasetriglycerides to total lipids in small LDL percentage

DMGDH MLXIPL CELSR2

1.37e-03591093EFO_0022337
Diseasecholesteryl esters to total lipids in large HDL percentage

MADD MLXIPL CELSR2

1.37e-03591093EFO_0022248
DiseaseIntellectual Disability

ZC3H14 MED13L PNPT1 AP2M1 RLIM MACF1 MAN1B1

1.38e-034471097C3714756
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

DMGDH MLXIPL CELSR2 SYNE2 MACF1

1.43e-032221095EFO_0008317, EFO_0020943
Diseasefree cholesterol to total lipids in medium HDL percentage

MADD MLXIPL CELSR2

1.44e-03601093EFO_0022282
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

DMGDH MLXIPL CELSR2 SYNE2 MACF1

1.49e-032241095EFO_0004530, EFO_0008317
Diseasenervousness

DENND1A MADD

1.57e-03161092NCIT_C74532
Diseasephospholipids:total lipids ratio

DMGDH MADD MLXIPL CELSR2 MACF1

1.57e-032271095EFO_0020946
Diseaseserum albumin measurement

COL7A1 KAT2A ALKBH5 MADD MLXIPL CSNK1G3 MACF1 PCDH7

1.62e-035921098EFO_0004535
Diseasetriglycerides to total lipids in IDL percentage

DMGDH MLXIPL CELSR2

1.66e-03631093EFO_0022329
Diseasetriglycerides to total lipids in medium VLDL percentage

DMGDH MLXIPL CELSR2

1.66e-03631093EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

DMGDH MLXIPL CELSR2

1.66e-03631093EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

DMGDH MLXIPL CELSR2

1.73e-03641093EFO_0022253
Diseaseresponse to radiation, Urinary retention

COL6A3 PTPRS

1.77e-03171092GO_0009314, HP_0000016
Diseasetotal lipids in very large HDL measurement

MADD MLXIPL CELSR2

1.89e-03661093EFO_0022312
DiseaseFEV/FEC ratio

HSPG2 COL6A3 CAMK1D NASP MCM7 NEB ARVCF PLEKHO2 CROCC2 SYNE2 CNTNAP2 TNXB

1.95e-03122810912EFO_0004713
Diseasecholesterol to total lipids in very small VLDL percentage

DMGDH MLXIPL CELSR2

1.98e-03671093EFO_0022245
Diseaseserum gamma-glutamyl transferase measurement

DMGDH TNFSF14 PERM1 MLXIPL CELSR2 CSNK1G3 OASL SLC17A8 PALM3 USP6NL

2.08e-0391410910EFO_0004532
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

DMGDH MADD MLXIPL CELSR2 MACF1

2.12e-032431095EFO_0004612, EFO_0020944
Diseasetriglycerides to total lipids in very small VLDL percentage

DMGDH MLXIPL CELSR2

2.15e-03691093EFO_0022341
Diseasecholesterol in very large HDL measurement

MADD MLXIPL CELSR2

2.15e-03691093EFO_0022229
DiseaseX-11470 measurement

VARS2 TNXB

2.22e-03191092EFO_0021241
Diseaseautism spectrum disorder (implicated_via_orthology)

TAOK2 ARVCF CNTNAP2 RIMS1

2.48e-031521094DOID:0060041 (implicated_via_orthology)
Diseaseunipolar depression, bipolar disorder

PCLO DENND1A TUBGCP6 SYNE2

2.72e-031561094EFO_0003761, MONDO_0004985
Diseasefree cholesterol to total lipids in small VLDL percentage

DMGDH MLXIPL CELSR2

2.73e-03751093EFO_0022287
Diseasefat intake measurement

NOL6 MLXIPL

2.98e-03221092EFO_0010809
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DMGDH MLXIPL CELSR2 SYNE2 MACF1

3.03e-032641095EFO_0008317, EFO_0020944
Diseaseapolipoprotein B measurement

FN1 PUM2 KANK2 MLXIPL CELSR2 CSNK1G3 SYNE2 BLOC1S3

3.24e-036631098EFO_0004615
Diseasesquamous cell lung carcinoma

VARS2 NEB RIMS1 TNXB

3.33e-031651094EFO_0000708
Diseasecomplex trait

EPHB4 TAOK2 MLXIPL OASL MACF1

3.39e-032711095EFO_0010578
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

DMGDH MADD MLXIPL CELSR2 MACF1

3.66e-032761095EFO_0004612, EFO_0020943

Protein segments in the cluster

PeptideGeneStartEntry
PDVVIPVRITGTTRG

ADAM29

31

Q9UKF5
RAVPVVSRTTPGIVT

CCDC187

686

A0A096LP49
RTRTRIGAETQEPEP

ANKLE1

136

Q8NAG6
VTTRTVRQVPVGPDG

ARVCF

131

O00192
EPVLSLPVRRGSVTV

ALKBH5

241

Q6P6C2
TAVISSPDPVRGEVV

ACSM2A

491

Q08AH3
APEETVPTGTRQQLI

CFAP46

846

Q8IYW2
VQVREDVTPGAPVLR

CELSR2

406

Q9HCU4
RPRTQGVVFESPEES

DCLRE1B

346

Q9H816
AVVVREGLPSAPTRV

IGDCC4

421

Q8TDY8
ITGTEPRIIRDPEAQ

NWD2

281

Q9ULI1
ISRDQSTPIIEVEGP

NR2C2

346

P49116
TTPSRREITGVQAQP

PALM

266

O75781
PPGTVIALVRVTDRD

PCDH17

366

O14917
VGSRLRIPQVTPADS

HSPG2

2581

P98160
PIRIESSSPTVVEGQ

HSPG2

2631

P98160
QVSGPERTIPITREE

CRYAB

151

P02511
RQIPVESVPGIRETG

KAT2A

701

Q92830
PGSRQASPTEVVERL

PUM2

176

Q8TB72
PITGERVLSPEAVRN

GLS

441

O94925
EIGRVPEVVQTSSPR

PALM3

291

A6NDB9
SPPRSGTALVRIEVV

PCDHB2

221

Q9Y5E7
GREIIQPTVVDPVSF

MTHFR

566

P42898
RSPVPVSGQKRVDIE

MADD

256

Q8WXG6
ESVTERERIGIPTEP

MED13L

1651

Q71F56
SRGPLTVEETPRVQG

MDC1

141

Q14676
SRRETIPQVQSSGVP

PSMG3-AS1

166

Q96PY0
REVPPAVSDIRVTRS

EPHB4

431

P54760
GSRPPEIREEEVQTV

RASGRP2

586

Q7LDG7
PTTPQNEEIRAVGRL

MFF

136

Q9GZY8
TRPRPSGEEVLQDIQ

MCM5

111

P33992
VRGTSENLPERSVPL

SLC43A1

281

O75387
PTVTIRTRGAIIQTP

DAG1

366

Q14118
VQTEPVGTIRTPSIR

PCLO

3526

Q9Y6V0
PVLTLTVEENRPVGT

PCDH7

146

O60245
EVNQRVVRVPSVPET

NOL6

111

Q9H6R4
TPLREVSADGPIQVT

KIF24

1006

Q5T7B8
RATVPAVTVSVPEGT

MACF1

906

O94854
RVGENVSDVAPTRPR

TUBGCP6

1116

Q96RT7
VKPTRTRVVSEVQRP

FMO6P

501

O60774
EVRIPTPLNTSGVQV

AP2M1

321

Q96CW1
GRSNAPITAPTEVEV

CSNK1G3

411

Q9Y6M4
VGDQTPIEPQTSIER

NASP

386

P49321
SDQVPVGNIPRSITV

MCM7

241

P33993
AVIEPEQGTELPSRR

MAN1B1

211

Q9UKM7
EQGTELPSRRAEVPT

MAN1B1

216

Q9UKM7
EVTTRPSTEEPVRRP

MORC2

596

Q9Y6X9
QTRGTAEPITVTIVP

OASL

141

Q15646
EGPPTVLSVRTRQQV

PTPRQ

596

Q9UMZ3
VVVRTDEDVPSAPPR

PTPRS

711

Q13332
SEPQVEIIVSRPIGD

RIMS1

681

Q86UR5
VPEAPVGRSTLQEVV

IGSF8

206

Q969P0
SGIVPVSPRIESVNV

E2F8

756

A0AVK6
TPVPTRIREIVAGSL

CROCC2

56

H7BZ55
EVSPVEIPGQTLRTA

ERICH4

26

A6NGS2
PVVIQQETTGTPRSD

FN1

891

P02751
QGVVTTLENVSPPRR

FN1

1896

P02751
RVSVVANTPSGPVEA

COL6A3

1886

P12111
LRRPETVVPGEATET

BLOC1S3

11

Q6QNY0
GETPQVAVIVRPDDR

EIF4G1

221

Q04637
QPGSIRLATTPVRVD

DMGDH

131

Q9UI17
NIAVEGRRTSVPSPE

DENND1A

511

Q8TEH3
PDSPVRVDTVRVVEG

KANK2

321

Q63ZY3
SVVVRTAPEPVGRVS

COL7A1

766

Q02388
DVGNGPVEIVVRSPT

CNTNAP2

861

Q9UHC6
STPVPVTEQGTDQIR

PERM1

256

Q5SV97
TTRPETLPGDVAVAV

VARS2

336

Q5ST30
PPEVTGRSSVLRVSQ

TACC3

26

Q9Y6A5
TLTRVNLESPGPERV

VGF

191

O15240
STQVVPPERRTALGV

TAPBPL

396

Q9BX59
EEETESRVPGSTRPQ

SYNE2

6811

Q8WXH0
PTVVAGRRKSVDQPE

TMEM132D

206

Q14C87
IEITVEPSQRPGTAI

TAB3

366

Q8N5C8
SIEVEAREISSPGRP

NHSL2

691

Q5HYW2
TIPEVSSVPDQIRGE

NBR1

841

Q14596
PLRDVTNRPEVGSTV

RIC8B

391

Q9NVN3
VPSLVPQERSIVGQE

TAOK2

851

Q9UL54
SNRPVEIVEDPRVVG

SETD1B

61

Q9UPS6
TTATGEIEIQPRVVP

NAP1L3

421

Q99457
PRASRKENGPVVETV

PNPT1

596

Q8TCS8
DPGRIPEQATRAVTE

MLXIPL

831

Q9NP71
VGAERRPRPTTVTAV

CAMK1D

366

Q8IU85
TAVISSPDPVRGEVV

ACSM2B

491

Q68CK6
SAVVSSPDPIRGEVV

ACSM3

506

Q53FZ2
VRVDSATIPRQDEVP

TNFRSF10D

51

Q9UBN6
EEVSPEAVGVTSQRP

TRIM24

206

O15164
RIGVQPSPERRSEVV

nan

21

Q9BTK2
AVTVPGPAEVRVSNV

USP6NL

516

Q92738
GDETEPTIIERSVQP

MIOS

306

Q9NXC5
GAIIRPVATSVAPET

SLC16A5

186

O15375
GPEETITQQGRTPRT

SARG

96

Q9BW04
VRPSVFVVDGQTDIP

TNFSF14

6

O43557
AVPRGEIEVVTSSLP

PWP2

781

Q15269
VVPQRGRSTRVPVAS

SPNS1

511

Q9H2V7
TEALTEVPPTRGQRR

RLIM

196

Q9NVW2
PRRPTQQGTVTFEDV

ZNF587

6

Q96SQ5
GSPIRVRSEITQPDR

TTBK2

421

Q6IQ55
DGPQDLRVVAVTPTT

TNXB

841

P22105
VPVEGPQRSAVITSL

TNXB

1106

P22105
QVVPVEGPERSFVVS

TNXB

1201

P22105
QPQVVPVEGSLREVS

TNXB

1816

P22105
RRVGPVSTVGVTAPQ

TNXB

2486

P22105
RRVGPVSTVGVTAPE

TNXB

2811

P22105
VVRVGTPPSDVSTRN

FAM170A

166

A1A519
PRRPTQQGTVTFEDV

ZNF417

6

Q8TAU3
RIRTENGSILPSVVP

ZNF654

1001

Q8IZM8
EETPSEQRISGERVP

ZNF211

81

Q13398
ERGQTTLPFRPVTQE

SMC6

1071

Q96SB8
GERPVVQRREPVSLE

TBC1D15

306

Q8TC07
RQGTTVPRDVPPDTV

VASN

41

Q6EMK4
QVTVPRPDVKGRTEI

YME1L1

501

Q96TA2
ITVPRGADEQRRSVP

USP41

86

Q3LFD5
QSVSVEGVPQVRTPE

ZNF416

81

Q9BWM5
GEAQVAREIPEPRTS

SNAPC4

1176

Q5SXM2
RVETPVGERAPTPVS

PLEKHO2

221

Q8TD55
ITVPRGADEQRRSVP

USP18

86

Q9UMW8
LSVRQESVEPQPRGV

ZSCAN29

131

Q8IWY8
VTVIPTERSRLGVGP

TMEM202

226

A6NGA9
AEVVQGQSRTPRISP

ZC3H14

396

Q6PJT7
QERSREVVGTAPGPV

THSD8

71

A0A1W2PP97
KRGEVVTIRVPTHPE

TMED8

186

Q6PL24
NVRRVEGTVPPDVLV

USP17L10

451

C9JJH3
IELNEEGRPVQTSRP

SLC17A8

46

Q8NDX2
GTGIPTTVTPEIERV

NEB

6221

P20929