Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inhibitory extracellular ligand-gated monoatomic ion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.85e-10	8	27	4	GO:0005237
GeneOntologyMolecularFunction	extracellularly glycine-gated ion channel activity	GLRA3 GLRA1 GLRA2	4.40e-08	6	27	3	GO:0016933
GeneOntologyMolecularFunction	extracellularly glycine-gated chloride channel activity	GLRA3 GLRA1 GLRA2	4.40e-08	6	27	3	GO:0016934
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	5.85e-07	50	27	4	GO:0099095
GeneOntologyMolecularFunction	glycine binding	GLRA3 GLRA1 GLRA2	7.95e-07	14	27	3	GO:0016594
GeneOntologyMolecularFunction	transmitter-gated channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.70e-06	65	27	4	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.70e-06	65	27	4	GO:0022824
GeneOntologyMolecularFunction	glycine-gated chloride ion channel activity	GLRA3 GLRA2	1.76e-06	2	27	2	GO:0022852
GeneOntologyMolecularFunction	amino acid binding	GLRA3 SLC38A9 GLRA1 GLRA2	2.71e-06	73	27	4	GO:0016597
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	3.35e-06	77	27	4	GO:0005230
GeneOntologyMolecularFunction	chloride channel activity	GLRA3 GLRA1 GLRA2 GABRA6	5.22e-06	86	27	4	GO:0005254
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GLRA3 GLRA1 GLRA2 GABRA6	9.51e-06	100	27	4	GO:0030594
GeneOntologyMolecularFunction	monoatomic anion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.07e-05	103	27	4	GO:0005253
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	GLRA3 GLRA1 GLRA2 GABRA6	2.30e-05	125	27	4	GO:0015108
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	GLRA3 GLRA1 GLRA2	2.62e-05	43	27	3	GO:0005231
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	GLRA3 GLRA1 GLRA2 GABRA6	4.82e-05	151	27	4	GO:0008509
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GLRA1 GLRA2 GABRA6	6.14e-05	57	27	3	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GLRA1 GLRA2 GABRA6	7.17e-05	60	27	3	GO:0099529
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GLRA3 GLRA1 GLRA2 GABRA6	7.81e-05	171	27	4	GO:0015103
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.25e-04	193	27	4	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	GLRA3 GLRA1 GLRA2 GABRA6	1.35e-04	197	27	4	GO:0022834
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GLRA1 GLRA2 GABRA6	1.40e-04	75	27	3	GO:0098960
GeneOntologyMolecularFunction	carboxylic acid binding	GLRA3 SLC38A9 GLRA1 GLRA2	2.83e-04	239	27	4	GO:0031406
GeneOntologyMolecularFunction	organic acid binding	GLRA3 SLC38A9 GLRA1 GLRA2	3.56e-04	254	27	4	GO:0043177
GeneOntologyMolecularFunction	gated channel activity	GLRA3 GLRA1 GLRA2 GABRA6	9.95e-04	334	27	4	GO:0022836
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GLRA3 OR52I1 BMPR2 GLRA1 GLRA2 OR10G7 GABRA6	1.72e-03	1353	27	7	GO:0004888
GeneOntologyMolecularFunction	monoatomic ion channel activity	GLRA3 GLRA1 GLRA2 GABRA6	3.18e-03	459	27	4	GO:0005216
GeneOntologyMolecularFunction	channel activity	GLRA3 GLRA1 GLRA2 GABRA6	5.13e-03	525	27	4	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GLRA3 GLRA1 GLRA2 GABRA6	5.16e-03	526	27	4	GO:0022803
GeneOntologyBiologicalProcess	cellular response to ethanol	GLRA3 GLRA1 GLRA2	4.51e-06	25	27	3	GO:0071361
GeneOntologyBiologicalProcess	cellular response to zinc ion	GLRA3 GLRA1 GLRA2	6.41e-06	28	27	3	GO:0071294
GeneOntologyBiologicalProcess	chloride transmembrane transport	GLRA3 GLRA1 GLRA2 GABRA6	1.31e-05	112	27	4	GO:1902476
GeneOntologyBiologicalProcess	chloride transport	GLRA3 GLRA1 GLRA2 GABRA6	2.22e-05	128	27	4	GO:0006821
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	GLRA3 GLRA1 GLRA2 GABRA6	2.66e-05	134	27	4	GO:0098661
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	GLRA3 GLRA1 GLRA2 GABRA6	4.47e-05	153	27	4	GO:0098656
GeneOntologyBiologicalProcess	cellular response to amino acid stimulus	GLRA3 SLC38A9 GLRA1 GLRA2	5.46e-05	161	27	4	GO:0071230
GeneOntologyBiologicalProcess	response to zinc ion	GLRA3 GLRA1 GLRA2	6.84e-05	61	27	3	GO:0010043
GeneOntologyBiologicalProcess	cellular response to acid chemical	GLRA3 SLC38A9 GLRA1 GLRA2	7.88e-05	177	27	4	GO:0071229
GeneOntologyBiologicalProcess	inorganic anion transport	GLRA3 GLRA1 GLRA2 GABRA6	8.41e-05	180	27	4	GO:0015698
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	GLRA3 GLRA1 GLRA2 GABRA6	8.41e-05	180	27	4	GO:0060078
GeneOntologyBiologicalProcess	monoatomic anion transport	GLRA3 GLRA1 GLRA2 GABRA6	8.97e-05	183	27	4	GO:0006820
GeneOntologyBiologicalProcess	response to amino acid	GLRA3 SLC38A9 GLRA1 GLRA2	1.31e-04	202	27	4	GO:0043200
GeneOntologyBiologicalProcess	cellular response to metal ion	GLRA3 GLRA1 GLRA2 ADD1	1.79e-04	219	27	4	GO:0071248
GeneOntologyBiologicalProcess	response to acid chemical	GLRA3 SLC38A9 GLRA1 GLRA2	2.09e-04	228	27	4	GO:0001101
GeneOntologyBiologicalProcess	ERAD pathway	UBE4A ECPAS RNF103	4.95e-04	119	27	3	GO:0036503
GeneOntologyBiologicalProcess	excitatory postsynaptic potential	GLRA3 GLRA1 GLRA2	6.41e-04	130	27	3	GO:0060079
GeneOntologyBiologicalProcess	cellular response to alcohol	GLRA3 GLRA1 GLRA2	6.41e-04	130	27	3	GO:0097306
GeneOntologyBiologicalProcess	chemical synaptic transmission, postsynaptic	GLRA3 GLRA1 GLRA2	9.15e-04	147	27	3	GO:0099565
GeneOntologyBiologicalProcess	response to ethanol	GLRA3 GLRA1 GLRA2	1.19e-03	161	27	3	GO:0045471
GeneOntologyCellularComponent	chloride channel complex	GLRA3 GLRA1 GLRA2 GABRA6	8.32e-07	57	27	4	GO:0034707
GeneOntologyCellularComponent	glycinergic synapse	GLRA3 GLRA1 GLRA2	2.16e-06	20	27	3	GO:0098690
GeneOntologyCellularComponent	postsynaptic specialization	GLRA3 BMPR2 GLRA1 GLRA2 ADD1 GABRA6	3.63e-05	503	27	6	GO:0099572
GeneOntologyCellularComponent	postsynaptic specialization membrane	GLRA3 GLRA1 GLRA2 GABRA6	1.22e-04	201	27	4	GO:0099634
GeneOntologyCellularComponent	dendrite	GLRA3 BMPR2 ATXN1L GLRA1 ADD1 GABRA6	6.63e-04	858	27	6	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GLRA3 BMPR2 ATXN1L GLRA1 ADD1 GABRA6	6.71e-04	860	27	6	GO:0097447
GeneOntologyCellularComponent	monoatomic ion channel complex	GLRA3 GLRA1 GLRA2 GABRA6	1.33e-03	378	27	4	GO:0034702
GeneOntologyCellularComponent	postsynapse	GLRA3 BMPR2 GLRA1 GLRA2 ADD1 GABRA6	1.61e-03	1018	27	6	GO:0098794
GeneOntologyCellularComponent	postsynaptic membrane	GLRA3 GLRA1 GLRA2 GABRA6	1.71e-03	405	27	4	GO:0045211
GeneOntologyCellularComponent	proteasome complex	PSMD2 ECPAS	3.37e-03	67	27	2	GO:0000502
GeneOntologyCellularComponent	somatodendritic compartment	GLRA3 BMPR2 ATXN1L GLRA1 ADD1 GABRA6	4.14e-03	1228	27	6	GO:0036477
GeneOntologyCellularComponent	transmembrane transporter complex	GLRA3 GLRA1 GLRA2 GABRA6	4.30e-03	523	27	4	GO:1902495
GeneOntologyCellularComponent	transporter complex	GLRA3 GLRA1 GLRA2 GABRA6	5.14e-03	550	27	4	GO:1990351
GeneOntologyCellularComponent	presynaptic membrane	GLRA3 GLRA1 GABRA6	5.32e-03	277	27	3	GO:0042734
GeneOntologyCellularComponent	synaptic membrane	GLRA3 GLRA1 GLRA2 GABRA6	6.31e-03	583	27	4	GO:0097060
GeneOntologyCellularComponent	intracellular protein-containing complex	UBE4A PSMD2 TRAPPC11 ECPAS SLC38A9	7.40e-03	972	27	5	GO:0140535
GeneOntologyCellularComponent	endopeptidase complex	PSMD2 ECPAS	7.64e-03	102	27	2	GO:1905369
Domain	Glycine_rcpt_A	GLRA3 GLRA1 GLRA2	1.08e-08	4	27	3	IPR008127
Domain	GABAA/Glycine_rcpt	GLRA3 GLRA1 GLRA2 GABRA6	3.01e-08	23	27	4	IPR006028
Domain	Neurotransmitter_ion_chnl_CS	GLRA3 GLRA1 GLRA2 GABRA6	4.95e-07	45	27	4	IPR018000
Domain	Neur_chan_memb	GLRA3 GLRA1 GLRA2 GABRA6	5.42e-07	46	27	4	PF02932
Domain	Neur_chan_LBD	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	PF02931
Domain	Neur_channel	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	IPR006201
Domain	Neur_chan_lig-bd	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	IPR006202
Domain	NEUROTR_ION_CHANNEL	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	PS00236
Domain	Neurotrans-gated_channel_TM	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	IPR006029
Domain	-	GLRA3 GLRA1 GLRA2 GABRA6	5.92e-07	47	27	4	2.70.170.10
Domain	UBA-like	VPS13D USP28	3.84e-03	64	27	2	IPR009060
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GLRA3 GLRA1 GLRA2 GABRA6	5.46e-05	144	21	4	MM14501
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GLRA3 GLRA1 GLRA2 GABRA6	2.14e-04	205	21	4	M752
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	GLRA3 GLRA1 GLRA2 GABRA6	2.39e-04	211	21	4	MM14502
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	GLRA3 GLRA1 GLRA2 GABRA6	6.09e-04	270	21	4	M15514
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	GLRA3 GLRA1 GLRA2 GABRA6	6.26e-04	272	21	4	M13380
Pubmed	Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice.	GLRA3 GLRA1 GLRA2	4.17e-10	3	27	3	17920294
Pubmed	Glycinergic input of widefield, displaced amacrine cells of the mouse retina.	GLRA3 GLRA1 GLRA2	1.67e-09	4	27	3	19528249
Pubmed	Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.	GLRA3 GLRA1 GLRA2	1.67e-09	4	27	3	9051263
Pubmed	Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.	GLRA3 GLRA1 GLRA2	1.67e-09	4	27	3	21486797
Pubmed	Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.	GLRA3 GLRA1 GLRA2	4.17e-09	5	27	3	21850450
Pubmed	Native glycine receptor subtypes and their physiological roles.	GLRA3 GLRA1 GLRA2	4.17e-09	5	27	3	18721822
Pubmed	Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.	GLRA3 GLRA1 GLRA2	1.46e-08	7	27	3	22988142
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	GLRA3 GLRA1 GLRA2 GABRA6	4.60e-07	81	27	4	22723691
Pubmed	Selective glycine receptor α2 subunit control of crossover inhibition between the on and off retinal pathways.	GLRA3 GLRA2	5.80e-07	2	27	2	22399754
Pubmed	Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.	GLRA3 GLRA2	5.80e-07	2	27	2	27382060
Pubmed	Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors.	GLRA1 GLRA2	5.80e-07	2	27	2	16144831
Pubmed	Structure of the human alpha 2 subunit gene of the glycine receptor--use of vectorette and Alu-exon PCR.	GLRA1 GLRA2	5.80e-07	2	27	2	8973915
Pubmed	Characterization of the glycinergic input to bipolar cells of the mouse retina.	GLRA3 GLRA1	5.80e-07	2	27	2	16420443
Pubmed	Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain.	GLRA3 GLRA2	5.80e-07	2	27	2	28784756
Pubmed	Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice.	GLRA1 GLRA2	5.80e-07	2	27	2	34378188
Pubmed	Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.	GLRA1 GLRA2	5.80e-07	2	27	2	2155780
Pubmed	Phylogenetic relationships and chromosomal location of five distinct glycine receptor subunit genes in the teleost Danio rerio.	GLRA1 GLRA2	5.80e-07	2	27	2	11685575
Pubmed	Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting.	GLRA3 GLRA1	5.80e-07	2	27	2	19959465
Pubmed	Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism.	GLRA1 GLRA2	5.80e-07	2	27	2	15147510
Pubmed	Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.	GLRA3 GLRA1	5.80e-07	2	27	2	21486794
Pubmed	Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site.	GLRA3 GLRA1	5.80e-07	2	27	2	23834509
Pubmed	Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.	GLRA3 GLRA1 GLRA2	1.21e-06	27	27	3	19723784
Pubmed	Diversity of glycine receptors in the mouse retina: localization of the alpha4 subunit.	GLRA3 GLRA1	1.74e-06	3	27	2	17154252
Pubmed	Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.	GLRA3 GLRA1	3.48e-06	4	27	2	28883437
Pubmed	Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variant.	GLRA1 GLRA2	3.48e-06	4	27	2	7507926
Pubmed	Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents.	GLRA1 GLRA2	8.69e-06	6	27	2	7891186
Pubmed	Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome.	GLRA3 GLRA2	3.81e-05	12	27	2	1679744
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	GLRA3 GLRA1 GLRA2 GABRA6	8.14e-05	300	27	4	19086053
Pubmed	Loss of transforming growth factor-beta 2 leads to impairment of central synapse function.	GLRA1 GLRA2	8.81e-05	18	27	2	18854036
Pubmed	Genetical genomic determinants of alcohol consumption in rats and humans.	GLRA1 GLRA2 GABRA6	1.40e-04	130	27	3	19874574
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	GLRA1 GLRA2	1.59e-04	24	27	2	20826655
Pubmed	The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.	EXTL3 ADD1	2.49e-04	30	27	2	24803591
Pubmed	Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.	GLRA3 GLRA2	2.49e-04	30	27	2	27568567
Pubmed	Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.	PSMD2 ECPAS	4.67e-04	41	27	2	32723828
Pubmed	The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress.	PSMD2 ECPAS	5.88e-04	46	27	2	28821611
GeneFamily	Glycine receptors	GLRA3 GLRA1 GLRA2	1.16e-08	5	20	3	868
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	GLRA3 VPS13D EXTL3 TBC1D1	3.12e-05	177	27	4	M9401
Coexpression	LEIN_MIDBRAIN_MARKERS	GLRA3 GLRA1 GLRA2	8.48e-05	83	27	3	M1720
Coexpression	LEIN_MIDBRAIN_MARKERS	GLRA3 GLRA1 GLRA2	1.01e-04	88	27	3	MM717
Coexpression	LEIN_PONS_MARKERS	GLRA1 GLRA2 SGPP2	1.15e-04	92	27	3	M1721
Coexpression	LEIN_PONS_MARKERS	GLRA1 GLRA2 SGPP2	1.27e-04	95	27	3	MM718
Computational	Neurotransmitter (GABA) receptor.	GLRA3 GLRA1 GLRA2 GABRA6	5.78e-09	15	17	4	MODULE_215
Computational	AcetylCholine receptors.	GLRA3 GLRA1 GLRA2	1.18e-06	14	17	3	MODULE_328
Computational	Genes in the cancer module 267.	GLRA3 GLRA1 GLRA2	1.48e-06	15	17	3	MODULE_267
Computational	Genes in the cancer module 141.	GLRA1 GLRA2 GABRA6	1.82e-06	16	17	3	MODULE_141
Computational	Ion channels.	GLRA3 GLRA1 GLRA2 GABRA6	3.68e-06	70	17	4	MODULE_316
Computational	Ion channels.	GLRA3 GLRA1 GLRA2	9.39e-06	27	17	3	MODULE_214
Computational	Genes in the cancer module 396.	GLRA2 GABRA6	1.54e-04	12	17	2	MODULE_396
Drug	iso-THAZ	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID003047783
Drug	SC-48981	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000126573
Drug	protostrychnine	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID005320746
Drug	7-nitroindoline	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID013566747
Drug	SC-50132	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000195719
Drug	2-(phosphonomethyl)phenylalanine	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000383689
Drug	SC-49648	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000195696
Drug	SR 42641	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000129049
Drug	akuammiline	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID005367018
Drug	NSC381080	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000165497
Drug	N-methyl-THIP	GLRA3 GLRA1 GLRA2	5.94e-09	4	27	3	CID000134373
Drug	R 5135	GLRA3 GLRA1 GLRA2 GABRA6	9.26e-09	21	27	4	CID000119544
Drug	azetidine-3-carboxylic acid	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000093192
Drug	Lindane	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	DB00431
Drug	Cao C	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000166617
Drug	oxanilide	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000069288
Drug	ALX1393	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID016078939
Drug	iso-THAO	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000127199
Drug	pleiocarpamine	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000558637
Drug	mafoprazine	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000071241
Drug	gevotroline	GLRA3 GLRA1 GLRA2	1.48e-08	5	27	3	CID000060546
Drug	SL 75102	GLRA3 GLRA1 GLRA2 GABRA6	1.64e-08	24	27	4	CID005751746
Drug	V-X-A	GLRA3 GLRA1 GLRA2 GABRA6	2.30e-08	26	27	4	CID006369389
Drug	pitrazepin	GLRA3 GLRA1 GLRA2 GABRA6	2.70e-08	27	27	4	CID000146222
Drug	thiomuscimol	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000005448
Drug	THAZ	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000171289
Drug	mV GABA	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000128435
Drug	caged glycine	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000192642
Drug	brometone	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000006424
Drug	thio-THIP	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000656720
Drug	AC1L90PQ	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000436036
Drug	minaxolone	GLRA3 GLRA1 GLRA2	2.97e-08	6	27	3	CID000071960
Drug	propyl methanethiosulfonate	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000529387
Drug	alpha-EMTBL	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000128423
Drug	thiocolchicoside	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000072067
Drug	L-serinamide	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000101138
Drug	Boc-glycine	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000078288
Drug	CID189778	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000189778
Drug	PK 8165	GLRA3 GLRA1 GLRA2	5.19e-08	7	27	3	CID000071219
Drug	WT702	GLRA3 GLRA1 GLRA2	8.30e-08	8	27	3	CID000089643
Drug	isostrychnine	GLRA3 GLRA1 GLRA2	8.30e-08	8	27	3	CID000264626
Drug	Atonik	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID000069471
Drug	nortropanol	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID000068147
Drug	DCQX	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID000001845
Drug	AC1NSJX8	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID005311059
Drug	NSC129536	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID000004815
Drug	SR 57227A	GLRA3 GLRA1 GLRA2	1.24e-07	9	27	3	CID000131746
Drug	5 beta-alphaxalone	GLRA3 GLRA1 GLRA2 GABRA6	1.70e-07	42	27	4	CID000068930
Drug	THBA	GLRA3 GLRA1 GLRA2	1.77e-07	10	27	3	CID000130993
Drug	TPMPA	GLRA3 GLRA1 GLRA2 GABRA6	2.26e-07	45	27	4	CID000005520
Drug	isoguvacine	GLRA3 GLRA1 GLRA2 GABRA6	2.26e-07	45	27	4	CID000003765
Drug	ip 0	GLRA3 GLRA1 GLRA2	2.44e-07	11	27	3	CID000006943
Drug	colchicoside	GLRA3 GLRA1 GLRA2	3.25e-07	12	27	3	CID000092763
Drug	quinoxaline-2,3-dione	GLRA3 GLRA1 GLRA2	5.37e-07	14	27	3	CID011469229
Drug	ABPH	GLRA3 GLRA1 GLRA2	5.37e-07	14	27	3	CID000092377
Drug	nipecotic acid	GLRA3 GLRA1 GLRA2 GABRA6	5.93e-07	57	27	4	CID000004498
Drug	ACEA-1011	GLRA3 GLRA1 GLRA2	6.70e-07	15	27	3	CID000127872
Drug	milacemide	GLRA3 GLRA1 GLRA2	6.70e-07	15	27	3	CID000053568
Drug	SR 95531	GLRA3 GLRA1 GLRA2 GABRA6	6.83e-07	59	27	4	CID000005275
Drug	2-hydroxysaclofen	GLRA3 GLRA1 GLRA2 GABRA6	6.83e-07	59	27	4	CID000001564
Drug	LY233536	GLRA3 GLRA1 GLRA2	8.24e-07	16	27	3	CID000126239
Drug	CGP 35348	GLRA3 GLRA1 GLRA2 GABRA6	8.35e-07	62	27	4	CID000107699
Drug	AP-7	GLRA3 GLRA1 GLRA2 GABRA6	8.90e-07	63	27	4	CID000003122
Drug	7-Cl-Thio-Kyna	GLRA3 GLRA1 GLRA2	1.00e-06	17	27	3	CID003035668
Drug	zatosetron	GLRA3 GLRA1 GLRA2	1.00e-06	17	27	3	CID000060763
Drug	picrotoxinine	GLRA3 GLRA1 GLRA2 GABRA6	1.01e-06	65	27	4	CID000004816
Drug	MNQX	GLRA3 GLRA1 GLRA2	1.20e-06	18	27	3	CID000130818
Drug	enflurane	GLRA3 GLRA1 GLRA2 GABRA6	1.21e-06	68	27	4	CID000003226
Drug	phaclofen	GLRA3 GLRA1 GLRA2 GABRA6	1.36e-06	70	27	4	CID000001641
Drug	felbamate	GLRA3 GLRA1 GLRA2 GABRA6	1.36e-06	70	27	4	CID000003331
Drug	AC1L1CMQ	GLRA3 GLRA1 GLRA2	1.42e-06	19	27	3	CID000001968
Drug	PNU-120596	GLRA3 GLRA1 GLRA2	1.42e-06	19	27	3	CID000311434
Drug	etomidate	GLRA3 GLRA1 GLRA2 GABRA6	1.44e-06	71	27	4	CID000036339
Drug	propanethiol	GLRA3 GLRA1 GLRA2	1.67e-06	20	27	3	CID000007848
Drug	di-Z	GLRA3 GLRA1 GLRA2	1.67e-06	20	27	3	CID000656933
Drug	ethyltrimethylammonium	GLRA3 GLRA1 GLRA2	1.95e-06	21	27	3	CID000033993
Drug	meproadifen	GLRA3 GLRA1 GLRA2	1.95e-06	21	27	3	CID000189752
Drug	Z-Gly	GLRA3 GLRA1 GLRA2	2.26e-06	22	27	3	CID000014349
Drug	DNQX	GLRA3 GLRA1 GLRA2 GABRA6	2.70e-06	83	27	4	CID003899541
Drug	propofol	GLRA3 AK7 GLRA1 GLRA2 GABRA6	2.74e-06	191	27	5	CID000004943
Drug	AC1L1B1W	GLRA3 GLRA1 GLRA2 GABRA6	2.84e-06	84	27	4	CID000001248
Drug	1-chloro-1,2,2-trifluorocyclobutane	GLRA3 GLRA1 GLRA2	2.96e-06	24	27	3	CID000079091
Drug	IPSP	GLRA3 GLRA1 GLRA2 GABRA6	3.26e-06	87	27	4	CID000022083
Drug	pregnanolone	GLRA3 GLRA1 GLRA2 GABRA6	3.74e-06	90	27	4	CID000031402
Drug	NBQX	GLRA3 GLRA1 GLRA2 GABRA6	3.74e-06	90	27	4	CID003272523
Drug	cyanotriphenylborate	GLRA1 GLRA2	4.06e-06	3	27	2	CID000151925
Drug	7-chloro-4-quinolinol	GLRA1 GLRA2	4.06e-06	3	27	2	CID000066593
Drug	L-689,560	GLRA3 GLRA1 GLRA2	4.27e-06	27	27	3	CID000121918
Drug	BN52020	GLRA3 GLRA1 GLRA2	4.78e-06	28	27	3	CID000115221
Drug	AC1NUW3V	GLRA3 GLRA1 GLRA2	5.32e-06	29	27	3	CID005462126
Drug	bilobalide	GLRA3 GLRA1 GLRA2	5.91e-06	30	27	3	CID000073581
Drug	Glycine	GLRA3 GLRA1 GLRA2	5.91e-06	30	27	3	DB00145
Drug	Blue Shield	GLRA3 GLRA1 GLRA2	5.91e-06	30	27	3	CID000014830
Drug	cyclothiazide	GLRA3 GLRA1 GLRA2 GABRA6	6.40e-06	103	27	4	CID000002910
Drug	methanethiosulfonate	GLRA3 GLRA1 GLRA2 GABRA6	6.40e-06	103	27	4	CID004188587
Drug	LY235959	GLRA3 GLRA1 GLRA2	6.54e-06	31	27	3	CID000131938
Drug	eliprodil	GLRA3 GLRA1 GLRA2	6.54e-06	31	27	3	CID000060703
Drug	NPC 12626	GLRA3 GLRA1 GLRA2	6.54e-06	31	27	3	CID000108099
Drug	beta-alanine	GLRA3 GLRA1 GLRA2 GABRA6	6.65e-06	104	27	4	CID000000239
Drug	sevoflurane	GLRA3 GLRA1 GLRA2 GABRA6	6.91e-06	105	27	4	CID000005206
Disease	hydrocephalus (implicated_via_orthology)	AK7 ADD1	1.37e-04	19	27	2	DOID:10908 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	PSMD2 EYS GLRA2 SGPP2	6.92e-04	447	27	4	EFO_0000694, MONDO_0100096
Disease	response to methotrexate, serum alanine aminotransferase measurement	ECPAS SGPP2	7.11e-04	43	27	2	EFO_0004735, GO_0031427
Disease	diastolic blood pressure, systolic blood pressure	GLRA3 TBC1D1 ADD1 GABRA6	3.05e-03	670	27	4	EFO_0006335, EFO_0006336
Disease	alcohol consumption measurement	GLRA3 PSMD2 USP28 TMEM216 SGPP2	4.88e-03	1242	27	5	EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
RQMGYYLIQMYIPSL	GLRA3	251	O75311
RYLAISYPLRYTNMM	OR10G7	121	Q8NGN6
MGNSYIKYIDPNYRM	EYS	2981	Q5T1H1
RMPIYYQMSRLPAGY	ATXN1L	226	P0C7T5
FMLDVLLMPYGYVLN	ECPAS	176	Q5VYK3
IYVMTLNLMYCYFPR	KBTBD2	431	Q8IY47
LQRKMGYFMIQIYTP	GABRA6	236	Q16445
YLYSYVMPQAIRDMV	EXTL3	811	O43909
GRMEYLLVMEYYPNG	BMPR2	271	Q13873
ERQMGYYLIQMYIPS	GLRA2	251	P23416
PMERYLFLFNNMLLY	FGD2	336	Q7Z6J4
YMTDIGIYNMPSYIL	RNF103	276	O00237
MMTVYPLLGYLARVQ	SLC38A9	451	Q8NBW4
VMALYYLPGMASIYA	OR52I1	251	Q8NGK6
YQGMLYSLPQYMIAL	STRIP2	506	Q9ULQ0
YVLYGLVAAMQPRML	PSMD2	816	Q13200
RQMGYYLIQMYIPSL	GLRA1	246	P23415
TMDRYQYPFVLGLVM	SGPP2	181	Q8IWX5
MRMLDNLGYRTGYPY	ADD1	381	P35611
MLYNFYPLMAGYQQL	TRAPPC11	1076	Q7Z392
YRPDMIILQIQMYQL	TBC1D1	926	Q86TI0
MRRMYGTSLYQFIPL	TTLL2	166	Q9BWV7
LEFPQIIYMDRYMYR	USP28	386	Q96RU2
KFNYRRPMYPILRYM	UBE4A	741	Q14139
MMASYYLLLQTYVLR	TMEM216	101	Q9P0N5
IPPGTQNYMVRMRLY	VPS13D	3241	Q5THJ4
RNYLMTYVMPTLIQG	AK7	681	Q96M32