Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of mesenchymal cell apoptotic process	MSX1 MSX2	5.14e-05	4	61	2	GO:2001055
GeneOntologyBiologicalProcess	embryonic nail plate morphogenesis	MSX1 MSX2	5.14e-05	4	61	2	GO:0035880
GeneOntologyBiologicalProcess	embryonic digit morphogenesis	MSX1 MSX2 IFT140 HOXD13	6.82e-05	74	61	4	GO:0042733
GeneOntologyBiologicalProcess	signal transduction involved in regulation of gene expression	MSX1 MSX2 GATA4	7.65e-05	28	61	3	GO:0023019
GeneOntologyBiologicalProcess	cranial skeletal system development	MSX2 IFT140 IRX5 FOXC2	1.12e-04	84	61	4	GO:1904888
GeneOntologyBiologicalProcess	skeletal system morphogenesis	PAPPA2 MSX1 MSX2 IFT140 IRX5 FOXC2	1.66e-04	277	61	6	GO:0048705
GeneOntologyBiologicalProcess	activation of meiosis	MSX1 MSX2	1.79e-04	7	61	2	GO:0090427
GeneOntologyBiologicalProcess	sulfur compound biosynthetic process	ACSBG1 GCLC GLCE ST3GAL3 ELOVL7	1.82e-04	178	61	5	GO:0044272
GeneOntologyBiologicalProcess	cardiac conduction system development	MSX1 MSX2 GATA4	2.25e-04	40	61	3	GO:0003161
GeneOntologyBiologicalProcess	embryonic morphogenesis	MSX1 MSX2 IFT140 IRX5 HOXD13 GATA4 EYA2 IRX2 FOXC2	2.33e-04	713	61	9	GO:0048598
GeneOntologyBiologicalProcess	positive regulation of BMP signaling pathway	MSX1 MSX2 GATA4	2.60e-04	42	61	3	GO:0030513
GeneOntologyBiologicalProcess	cell surface receptor signaling pathway involved in heart development	MSX1 MSX2	3.06e-04	9	61	2	GO:0061311
GeneOntologyBiologicalProcess	tissue morphogenesis	MSX1 MSX2 FLNA HOXD13 MTSS1 GATA4 EYA2 IRX2 FOXC2	3.38e-04	750	61	9	GO:0048729
GeneOntologyBiologicalProcess	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	MSX1 MSX2 GLCE GATA4	3.75e-04	115	61	4	GO:0090100
GeneOntologyBiologicalProcess	skeletal system development	PAPPA2 MSX1 MSX2 IFT140 IRX5 HOXD13 ANO6 FOXC2	4.37e-04	615	61	8	GO:0001501
GeneOntologyBiologicalProcess	nail development	MSX1 MSX2	4.65e-04	11	61	2	GO:0035878
GeneOntologyBiologicalProcess	embryonic cranial skeleton morphogenesis	IFT140 IRX5 FOXC2	4.91e-04	52	61	3	GO:0048701
GeneOntologyBiologicalProcess	regionalization	MSX1 MSX2 IFT140 HOXD13 GATA4 IRX2 FOXC2	5.09e-04	478	61	7	GO:0003002
HumanPheno	Abnormality of the fifth metatarsal bone	FLNA TCF4 HOXD13	1.36e-05	9	29	3	HP:0008089
MousePheno	absent palatine bone horizontal plate	MSX1 PAX9 FOXC2	1.35e-05	14	48	3	MP:0000431
MousePheno	abnormal palatine bone morphology	MSX1 IFT140 PAX9 FOXC2	1.80e-05	46	48	4	MP:0005249
MousePheno	absent alveolar process	MSX1 PAX9	3.46e-05	3	48	2	MP:0000094
MousePheno	absent palatine bone	IFT140 FOXC2	1.15e-04	5	48	2	MP:0004476
MousePheno	abnormal palatine bone horizontal plate morphology	MSX1 PAX9 FOXC2	1.17e-04	28	48	3	MP:0004537
MousePheno	absent molars	MSX1 PAX9	1.72e-04	6	48	2	MP:0003931
MousePheno	abnormal tympanic ring morphology	IFT140 PAX9 FOXC2	1.93e-04	33	48	3	MP:0000030
MousePheno	small malleus	MSX1 FOXC2	2.40e-04	7	48	2	MP:0008372
MousePheno	abnormal middle ear morphology	MSX1 IFT140 PAX9 FOXC2	2.74e-04	92	48	4	MP:0000049
MousePheno	growth retardation of molars	MSX1 PAX9	3.19e-04	8	48	2	MP:0000128
MousePheno	absent lower incisors	MSX1 PAX9	3.19e-04	8	48	2	MP:0004791
MousePheno	interrupted aortic arch	FLNA PAX9 FOXC2	3.70e-04	41	48	3	MP:0004157
MousePheno	palatal shelf hypoplasia	MSX1 IFT140	4.09e-04	9	48	2	MP:0009883
MousePheno	interrupted aorta	FLNA PAX9 FOXC2	4.26e-04	43	48	3	MP:0010544
MousePheno	cleft palate	MSX1 FLNA IFT140 GLCE PAX9 FOXC2	4.38e-04	289	48	6	MP:0000111
MousePheno	oral cleft	MSX1 FLNA IFT140 GLCE PAX9 FOXC2	4.55e-04	291	48	6	MP:0021164
MousePheno	abnormal sperm principal piece morphology	TSSK4 DNAH8 QRICH2	4.87e-04	45	48	3	MP:0009836
MousePheno	abnormal iris morphology	MSX2 FLNA GLCE TSSK4 FOXC2	4.92e-04	192	48	5	MP:0001322
MousePheno	absent maxillary shelf	MSX1 PAX9	5.11e-04	10	48	2	MP:0000430
MousePheno	abnormal anterior uvea morphology	MSX2 FLNA GLCE TSSK4 FOXC2	5.79e-04	199	48	5	MP:0005194
MousePheno	absent facial bone	MSX1 IFT140 FOXC2	6.27e-04	49	48	3	MP:0030385
MousePheno	small mandible	PAPPA2 MSX1 PAX9 FOXC2	6.61e-04	116	48	4	MP:0004592
MousePheno	abnormal palate bone morphology	MSX1 PAX9 FOXC2	7.05e-04	51	48	3	MP:0009891
MousePheno	abnormal molar morphology	MSX1 MSX2 PAX9	7.05e-04	51	48	3	MP:0002689
MousePheno	abnormal aortic arch morphology	FLNA IFT140 PAX9 FOXC2	7.28e-04	119	48	4	MP:0004113
MousePheno	abnormal exoccipital bone morphology	IFT140 FOXC2	7.45e-04	12	48	2	MP:0000080
MousePheno	abnormal palate morphology	MSX1 FLNA IFT140 GLCE PAX9 FOXC2	7.62e-04	321	48	6	MP:0003755
MousePheno	abnormal palatal shelf morphology	MSX1 FLNA IFT140 PAX9	7.74e-04	121	48	4	MP:0031460
MousePheno	abnormal secondary palate development	MSX1 FLNA IFT140 PAX9	8.49e-04	124	48	4	MP:0009655
MousePheno	abnormal third pharyngeal arch artery morphology	PAX9 FOXC2	8.79e-04	13	48	2	MP:0006356
MousePheno	common ventricle	FLNA GATA4	8.79e-04	13	48	2	MP:0010432
MousePheno	cleft secondary palate	MSX1 FLNA PAX9 FOXC2	9.28e-04	127	48	4	MP:0009890
MousePheno	polydactyly	IFT140 HOXD13 GLCE PAX9	9.84e-04	129	48	4	MP:0000562
MousePheno	abnormal palate development	MSX1 FLNA IFT140 PAX9	9.84e-04	129	48	4	MP:0009653
MousePheno	abnormal aorta morphology	FLNA IFT140 GATA4 PAX9 FOXC2	1.01e-03	225	48	5	MP:0000272
MousePheno	decreased molar number	MSX1 PAX9	1.02e-03	14	48	2	MP:0006400
MousePheno	abnormal thoracic aorta morphology	FLNA IFT140 PAX9 FOXC2	1.13e-03	134	48	4	MP:0010468
MousePheno	polysyndactyly	HOXD13 PAX9	1.18e-03	15	48	2	MP:0004083
MousePheno	decreased tympanic ring size	PAX9 FOXC2	1.18e-03	15	48	2	MP:0006020
MousePheno	absent incisors	MSX1 PAX9	1.18e-03	15	48	2	MP:0000125
MousePheno	abnormal uvea morphology	MSX2 FLNA GLCE TSSK4 FOXC2	1.37e-03	241	48	5	MP:0005197
Domain	Homeodomain-like	MSX1 MSX2 TCF4 IRX5 HOXD13 PAX9 IRX2	1.01e-04	332	61	7	IPR009057
Domain	IRO	IRX5 IRX2	1.56e-04	6	61	2	SM00548
Domain	Iroquois_homeo	IRX5 IRX2	1.56e-04	6	61	2	IPR003893
Domain	6hp_glycosidase	PHKA2 LANCL3	2.90e-04	8	61	2	IPR012341
Domain	-	PHKA2 LANCL3	2.90e-04	8	61	2	1.50.10.10
Domain	Homeobox_CS	MSX1 MSX2 IRX5 HOXD13 IRX2	3.52e-04	186	61	5	IPR017970
Domain	IG_FLMN	FLNA FLNC	4.64e-04	10	61	2	SM00557
Domain	Filamin	FLNA FLNC	5.66e-04	11	61	2	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNC	5.66e-04	11	61	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNC	5.66e-04	11	61	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC	5.66e-04	11	61	2	IPR017868
Domain	6-hairpin_glycosidase-like	PHKA2 LANCL3	8.00e-04	13	61	2	IPR008928
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DNAH1	9.31e-04	14	61	2	IPR024317
Domain	Dynein_HC_stalk	DNAH8 DNAH1	9.31e-04	14	61	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH8 DNAH1	9.31e-04	14	61	2	IPR013602
Domain	DHC_N2	DNAH8 DNAH1	9.31e-04	14	61	2	PF08393
Domain	MT	DNAH8 DNAH1	9.31e-04	14	61	2	PF12777
Domain	AAA_8	DNAH8 DNAH1	9.31e-04	14	61	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH8 DNAH1	9.31e-04	14	61	2	IPR011704
Domain	AAA_5	DNAH8 DNAH1	9.31e-04	14	61	2	PF07728
Domain	Homeobox	MSX1 MSX2 IRX5 HOXD13 IRX2	9.94e-04	234	61	5	PF00046
Domain	HOMEOBOX_1	MSX1 MSX2 IRX5 HOXD13 IRX2	1.03e-03	236	61	5	PS00027
Domain	HOX	MSX1 MSX2 IRX5 HOXD13 IRX2	1.05e-03	237	61	5	SM00389
Domain	DHC_fam	DNAH8 DNAH1	1.07e-03	15	61	2	IPR026983
Domain	Dynein_heavy_dom	DNAH8 DNAH1	1.07e-03	15	61	2	IPR004273
Domain	Dynein_heavy	DNAH8 DNAH1	1.07e-03	15	61	2	PF03028
Domain	HOMEOBOX_2	MSX1 MSX2 IRX5 HOXD13 IRX2	1.09e-03	239	61	5	PS50071
Domain	Homeobox_dom	MSX1 MSX2 IRX5 HOXD13 IRX2	1.09e-03	239	61	5	IPR001356
Domain	CH	FLNA FLNC MICALL2	1.25e-03	65	61	3	SM00033
Domain	Homeobox_KN	IRX5 IRX2	1.38e-03	17	61	2	PF05920
Domain	Homeobox_KN_domain	IRX5 IRX2	1.38e-03	17	61	2	IPR008422
Domain	CH	FLNA FLNC MICALL2	1.55e-03	70	61	3	PF00307
Domain	-	FLNA FLNC MICALL2	1.62e-03	71	61	3	1.10.418.10
Domain	CH	FLNA FLNC MICALL2	1.75e-03	73	61	3	PS50021
Domain	CH-domain	FLNA FLNC MICALL2	1.89e-03	75	61	3	IPR001715
Domain	CRAL_TRIO	MOSPD2 ATCAY	2.12e-03	21	61	2	PF00650
Domain	-	MSX1 MSX2 IRX5 HOXD13 IRX2	2.30e-03	283	61	5	1.10.10.60
Domain	GRAM	WBP2 NSMAF	2.32e-03	22	61	2	PF02893
Domain	GRAM	WBP2 NSMAF	2.32e-03	22	61	2	IPR004182
Domain	Actinin_actin-bd_CS	FLNA FLNC	2.54e-03	23	61	2	IPR001589
Domain	-	MOSPD2 ATCAY	2.54e-03	23	61	2	3.40.525.10
Domain	ACTININ_2	FLNA FLNC	2.54e-03	23	61	2	PS00020
Domain	ACTININ_1	FLNA FLNC	2.54e-03	23	61	2	PS00019
Domain	SEC14	MOSPD2 ATCAY	3.00e-03	25	61	2	SM00516
Domain	CRAL_TRIO	MOSPD2 ATCAY	3.49e-03	27	61	2	PS50191
Domain	CRAL-TRIO_dom	MOSPD2 ATCAY	3.76e-03	28	61	2	IPR001251
Pubmed	Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.	MSX1 MSX2 PAX9	5.66e-09	3	63	3	28710291
Pubmed	The incomplete inactivation of Fgf8 in the limb ectoderm affects the morphogenesis of the anterior autopod through BMP-mediated cell death.	MSX1 MSX2 HOXD13 PAX9	6.90e-09	13	63	4	18265010
Pubmed	Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb.	MSX1 MSX2 HOXD13 PAX9	6.90e-09	13	63	4	19422820
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	MSX1 MSX2 IRX5 PAX9 EYA2 IRX2 FOXC2	5.76e-08	191	63	7	24146773
Pubmed	HMGB factors are required for posterior digit development through integrating signaling pathway activities.	MSX1 MSX2 HOXD13 PAX9	6.98e-08	22	63	4	21384471
Pubmed	Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb.	MSX1 MSX2 HOXD13 PAX9	8.43e-08	23	63	4	19783740
Pubmed	Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryos.	MSX1 MSX2 GATA4	1.13e-07	6	63	3	21089072
Pubmed	Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway.	MSX2 IRX5 HOXD13 PAX9	2.24e-07	29	63	4	26959361
Pubmed	In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma.	MSX2 IRX5 IRX2	3.15e-07	8	63	3	33206716
Pubmed	Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.	MSX1 MSX2 PAX9	4.72e-07	9	63	3	19648291
Pubmed	Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development.	MSX1 MSX2 HOXD13	4.72e-07	9	63	3	34584102
Pubmed	Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.	MSX2 IRX5 GATA4 FOXC2	5.51e-07	36	63	4	27606604
Pubmed	GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.	MSX1 MSX2 HOXD13 PAX9	6.17e-07	37	63	4	22465667
Pubmed	Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development.	MSX1 MSX2 PAX9	9.25e-07	11	63	3	32467233
Pubmed	Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4.	MSX1 MSX2 FOXC2	9.25e-07	11	63	3	14512019
Pubmed	Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5.	MSX1 MSX2 IRX5 MUC1	1.26e-06	44	63	4	29463648
Pubmed	Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration.	MSX1 MSX2 PAX9	1.60e-06	13	63	3	14623826
Pubmed	Developmental plasticity of epithelial stem cells in tooth and taste bud renewal.	MSX1 MSX2 PAX9	1.60e-06	13	63	3	31427537
Pubmed	Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero.	MSX1 MSX2 PAX9	1.60e-06	13	63	3	28893947
Pubmed	Molecular markers of cardiac endocardial cushion development.	MSX1 MSX2 FOXC2	1.60e-06	13	63	3	14648841
Pubmed	In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.	MSX1 MSX2 HOXD13	2.03e-06	14	63	3	12217322
Pubmed	Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.	MSX1 MSX2 PAX9	2.03e-06	14	63	3	18022614
Pubmed	Teeth. Where and how to make them.	MSX1 MSX2 PAX9	2.54e-06	15	63	3	10098408
Pubmed	Prx1 and Prx2 cooperatively regulate the morphogenesis of the medial region of the mandibular process.	MSX1 MSX2 PAX9	2.54e-06	15	63	3	19777594
Pubmed	BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning.	MSX1 MSX2 HOXD13	2.54e-06	15	63	3	16630606
Pubmed	Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods.	MSX1 MSX2 HOXD13	3.12e-06	16	63	3	10075839
Pubmed	Hand transcription factors cooperatively regulate development of the distal midline mesenchyme.	MSX1 MSX2 PAX9	3.12e-06	16	63	3	17764670
Pubmed	Smad4 is required to regulate the fate of cranial neural crest cells.	MSX1 MSX2 PAX9	3.12e-06	16	63	3	17964566
Pubmed	Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene.	MSX1 MSX2	3.23e-06	2	63	2	9256350
Pubmed	Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development.	MSX1 MSX2	3.23e-06	2	63	2	9142497
Pubmed	Role of polymorphisms of MSX1 and PAX9 genes in palatal impaction of maxillary canines.	MSX1 PAX9	3.23e-06	2	63	2	31056064
Pubmed	Msx1 and Msx2 gene expression is downregulated in the cadmium-induced omphalocele in the chick model.	MSX1 MSX2	3.23e-06	2	63	2	20620318
Pubmed	MSX-1 gene expression and regulation in embryonic palatal tissue.	MSX1 MSX2	3.23e-06	2	63	2	9870533
Pubmed	Ventral abdominal wall dysmorphogenesis of Msx1/Msx2 double-mutant mice.	MSX1 MSX2	3.23e-06	2	63	2	15803476
Pubmed	Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape.	MSX1 MSX2	3.23e-06	2	63	2	1358591
Pubmed	PAX9 and MSX1 transcription factor genes in non-syndromic dental agenesis.	MSX1 PAX9	3.23e-06	2	63	2	21111400
Pubmed	Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud.	MSX1 MSX2	3.23e-06	2	63	2	7537232
Pubmed	Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian.	MSX1 MSX2	3.23e-06	2	63	2	1673109
Pubmed	Differential impact of MSX1 and MSX2 homeogenes on mouse maxillofacial skeleton.	MSX1 MSX2	3.23e-06	2	63	2	18769023
Pubmed	Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy.	MSX1 MSX2	3.23e-06	2	63	2	8861098
Pubmed	Regulated expression of homeobox genes Msx-1 and Msx-2 in mouse mammary gland development suggests a role in hormone action and epithelial-stromal interactions.	MSX1 MSX2	3.23e-06	2	63	2	8660900
Pubmed	Studies on Pax9-Msx1 protein interactions.	MSX1 PAX9	3.23e-06	2	63	2	15721141
Pubmed	Exclusion of PAX9 and MSX1 mutation in six families affected by tooth agenesis. A genetic study and literature review.	MSX1 PAX9	3.23e-06	2	63	2	24316698
Pubmed	Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth.	MSX1 MSX2	3.23e-06	2	63	2	8101167
Pubmed	Mutational analysis of MSX1 and PAX9 genes in Portuguese families with maxillary lateral incisor agenesis.	MSX1 PAX9	3.23e-06	2	63	2	20660504
Pubmed	Mutational analysis of AXIN2, MSX1, and PAX9 in two Mexican oligodontia families.	MSX1 PAX9	3.23e-06	2	63	2	24222224
Pubmed	Conditional alleles of Msx1 and Msx2.	MSX1 MSX2	3.23e-06	2	63	2	17654563
Pubmed	Msx homeobox gene family and craniofacial development.	MSX1 MSX2	3.23e-06	2	63	2	14728799
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	3.23e-06	2	63	2	7689010
Pubmed	Msh homeobox 1 (Msx1)- and Msx2-overexpressing bone marrow-derived mesenchymal stem cells resemble blastema cells and enhance regeneration in mice.	MSX1 MSX2	3.23e-06	2	63	2	28461333
Pubmed	Concomitant occurrence of canine malposition and tooth agenesis: evidence of orofacial genetic fields.	MSX1 PAX9	3.23e-06	2	63	2	12490878
Pubmed	[Induction phenomena during vertebrate limb development and homeo box gene expression].	MSX1 MSX2	3.23e-06	2	63	2	8099267
Pubmed	The Msh-like homeobox genes define domains in the developing vertebrate eye.	MSX1 MSX2	3.23e-06	2	63	2	1682128
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	3.23e-06	2	63	2	10679933
Pubmed	Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth.	MSX1 PAX9	3.23e-06	2	63	2	28040065
Pubmed	Generation of an Msx2-GFP conditional null allele.	MSX1 MSX2	3.23e-06	2	63	2	18442049
Pubmed	Rescue of the limb deformity in hammertoe mutant mice by retinoic acid-induced cell death.	MSX1 MSX2	3.23e-06	2	63	2	9097019
Pubmed	[Correlation between the phenotype and genotype of tooth agenesis patients by tooth agenesis code].	MSX1 PAX9	3.23e-06	2	63	2	20602873
Pubmed	The function and evolution of Msx genes: pointers and paradoxes.	MSX1 MSX2	3.23e-06	2	63	2	7482767
Pubmed	Loss of homeoprotein Msx1 and Msx2 leading to athletic and kinematic impairment related to the increasing neural excitability of neurons in aberrant neocortex in mice.	MSX1 MSX2	3.23e-06	2	63	2	31221479
Pubmed	Position-dependent expression of two related homeobox genes in developing vertebrate limbs.	MSX1 MSX2	3.23e-06	2	63	2	1677742
Pubmed	Associations between the risk of tooth agenesis and single-nucleotide polymorphisms of MSX1 and PAX9 genes in nonsyndromic cleft patients.	MSX1 PAX9	3.23e-06	2	63	2	23718693
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	3.23e-06	2	63	2	24469451
Pubmed	Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development.	MSX1 MSX2 HOXD13	3.78e-06	17	63	3	19766620
Pubmed	FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart.	MSX1 MSX2 GATA4	3.78e-06	17	63	3	17274974
Pubmed	Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling.	IRX5 HOXD13 PAX9	3.78e-06	17	63	3	24726282
Pubmed	Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract.	MSX1 MSX2 FOXC2	4.53e-06	18	63	3	16839542
Pubmed	Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function.	MSX1 MSX2 HOXD13	4.53e-06	18	63	3	11476582
Pubmed	Wnt/β-catenin promotes gastric fundus specification in mice and humans.	IRX5 GATA4 IRX2	4.53e-06	18	63	3	28052057
Pubmed	Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.	MSX1 PAX9 FOXC2	5.38e-06	19	63	3	15107405
Pubmed	Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4.	MSX1 MSX2 PAX9	5.38e-06	19	63	3	20883686
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	MSX1 MSX2 TCF4 IRX5 HOXD13 GATA4 PAX9 FOXC2	6.19e-06	544	63	8	28473536
Pubmed	Msx1 and Msx2 in limb mesenchyme modulate digit number and identity.	MSX1 MSX2 PAX9	6.32e-06	20	63	3	21465616
Pubmed	Delineating a conserved genetic cassette promoting outgrowth of body appendages.	MSX1 MSX2 HOXD13	6.32e-06	20	63	3	23358455
Pubmed	Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression.	MSX1 MSX2 HOXD13	6.32e-06	20	63	3	10534616
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	MSX1 MSX2 FOXC2	6.32e-06	20	63	3	12812790
Pubmed	The formation and function of the cardiac conduction system.	MSX1 MSX2 GATA4	7.36e-06	21	63	3	26786210
Pubmed	Functions of FGF signalling from the apical ectodermal ridge in limb development.	MSX1 MSX2 HOXD13	7.36e-06	21	63	3	12152071
Pubmed	FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis.	MSX1 MSX2 HOXD13	7.36e-06	21	63	3	16207751
Pubmed	Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development.	MSX1 MSX2 FOXC2	7.36e-06	21	63	3	28794157
Pubmed	Cooperation of BMP and IHH signaling in interdigital cell fate determination.	MSX1 MSX2 HOXD13	7.36e-06	21	63	3	29771958
Pubmed	Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.	MSX1 MSX2 HOXD13	8.51e-06	22	63	3	19223390
Pubmed	Pax6 regulates craniofacial form through its control of an essential cephalic ectodermal patterning center.	MSX1 MSX2 EYA2	8.51e-06	22	63	3	21309073
Pubmed	Characteristic tissue interaction of the diastema region in mice.	MSX1 MSX2	9.68e-06	3	63	2	15812993
Pubmed	Analysis of Msx1 and Msx2 transactivation function in the context of the heat shock 70 (Hspa1b) gene promoter.	MSX1 MSX2	9.68e-06	3	63	2	19338779
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNC	9.68e-06	3	63	2	11252955
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	9.68e-06	3	63	2	12704190
Pubmed	Regulation of proliferation in developing human tooth germs by MSX homeodomain proteins and cyclin-dependent kinase inhibitor p19INK4d.	MSX1 MSX2	9.68e-06	3	63	2	28933666
Pubmed	Influence of FGF4 on digit morphogenesis during limb development in the mouse.	MSX1 HOXD13	9.68e-06	3	63	2	10694418
Pubmed	Msx1CreERT2 knock-In allele: A useful tool to target embryonic and adult cardiac valves.	MSX1 MSX2	9.68e-06	3	63	2	25950518
Pubmed	A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma.	MSX1 MSX2	9.68e-06	3	63	2	32210188
Pubmed	The murine homeobox gene Msx-3 shows highly restricted expression in the developing neural tube.	MSX1 MSX2	9.68e-06	3	63	2	8861099
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	9.68e-06	3	63	2	11038172
Pubmed	Study of rs12532, rs8670 Polymorphism of Msh Homeobox 1 (MSX1), rs61754301, rs4904155 Polymorphism of Paired Box Gene 9 (PAX9), and rs2240308 Polymorphism of Axis Inhibitor Protein 2 (AXIN2) Genes in Nonsyndromic Hypodontia.	MSX1 PAX9	9.68e-06	3	63	2	31781599
Pubmed	Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis.	MSX1 PAX9	9.68e-06	3	63	2	35273362
Pubmed	SNPs and interaction analyses of IRF6, MSX1 and PAX9 genes in patients with non‑syndromic cleft lip with or without palate.	MSX1 PAX9	9.68e-06	3	63	2	23921572
Pubmed	Msx Homeobox Genes Act Downstream of BMP2 to Regulate Endometrial Decidualization in Mice and in Humans.	MSX1 MSX2	9.68e-06	3	63	2	31125045
Pubmed	LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2.	MSX1 MSX2	9.68e-06	3	63	2	25460335
Pubmed	Targeted reduction of vascular Msx1 and Msx2 mitigates arteriosclerotic calcification and aortic stiffness in LDLR-deficient mice fed diabetogenic diets.	MSX1 MSX2	9.68e-06	3	63	2	25056439
Pubmed	Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice.	MSX1 MSX2	9.68e-06	3	63	2	7538067
Cytoband	1q44	OR2T29 OR11L1 OR2T7 OR2T5	1.67e-05	110	63	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2T29 OR11L1 OR2T7 OR2T5	3.02e-05	128	63	4	chr1q44
GeneFamily	WD repeat domain containing\|GRAM domain containing\|BEACH domain containing	WBP2 NSMAF	4.44e-04	13	44	2	1146
GeneFamily	Dyneins, axonemal	DNAH8 DNAH1	7.69e-04	17	44	2	536
GeneFamily	TALE class homeoboxes and pseudogenes	IRX5 IRX2	1.81e-03	26	44	2	526
GeneFamily	Olfactory receptors, family 2	OR2T29 OR2T7 OR2T5	2.61e-03	113	44	3	149
Coexpression	HELLER_HDAC_TARGETS_UP	MSX1 IFT140 SAT1 MICALL2 ACSBG1 GLCE GATA4	7.05e-06	317	59	7	M3335
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500	MSX1 MSX2 TCF4 IRX5 HOXD13	1.69e-06	72	59	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500	MSX1 MSX2 TCF4 IRX5 HOXD13 ERC2	3.05e-05	217	59	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#3_top-relative-expression-ranked_100	MSX1 MSX2 IRX5	5.68e-05	27	59	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_ureter_emap-29479_k-means-cluster#1_top-relative-expression-ranked_500	IRX5 HOXD13 PAX9 IRX2 ELOVL7	5.87e-05	149	59	5	gudmap_developingLowerUrinaryTract_adult_ureter_500_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_100	MSX1 MSX2 IRX5 HOXD13	6.58e-05	78	59	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_ureter_emap-29479_top-relative-expression-ranked_500	IRX5 SAT1 HOXD13 TLCD4 PAX9 IRX2 ELOVL7	7.59e-05	373	59	7	gudmap_developingLowerUrinaryTract_adult_ureter_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	MSX1 MSX2 TCF4 IRX5 MICALL2 HOXD13 ERC2	8.11e-05	377	59	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_200	IRX5 HOXD13 PAX9 IRX2 ELOVL7	1.04e-04	168	59	5	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200	MSX1 MSX2 IRX5 HOXD13 ERC2	1.06e-04	169	59	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_200	MSX1 MSX2 IRX5	1.48e-04	37	59	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000	MSX1 MSX2 TCF4 IRX5	1.60e-04	98	59	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500	MSX1 MSX2 TCF4 IRX5 MICALL2 HOXD13 ERC2	1.78e-04	428	59	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_ureter_emap-29479_top-relative-expression-ranked_1000	LANCL3 IRX5 SAT1 HOXD13 TLCD4 PAX9 EYA2 IRX2 ELOVL7	1.83e-04	736	59	9	gudmap_developingLowerUrinaryTract_adult_ureter_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100	KLHL23 GATA4	2.10e-04	8	59	2	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_100
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_100	KLHL23 GATA4	2.70e-04	9	59	2	gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_100
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_100	KLHL23 GATA4	2.70e-04	9	59	2	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000	MSX1 MSX2 TCF4 IRX5	3.26e-04	118	59	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k3
CoexpressionAtlas	ECTO blastocyst_vs_ECTO fibroblast-Confounder_removed-fold2.0_adjp0.05	MSX1 MSX2 MTSS1 IRX2	3.26e-04	118	59	4	PCBC_ratio_ECTO blastocyst_vs_ECTO fibroblast_cfr-2X-p05
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_100	KLHL23 GATA4	3.37e-04	10	59	2	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_100
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100	KLHL23 GATA4	3.37e-04	10	59	2	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_100
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#3_top-relative-expression-ranked_1000	GCLC MUC1 IRX2 ELOVL7	4.57e-04	129	59	4	gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	MSX1 MSX2 TCF4 IRX5 MOSPD2 HOXD13 TLCD4 ERC2 ELOVL7	4.67e-04	836	59	9	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000	MSX1 MSX2 TCF4 IRX5 MICALL2 HOXD13 TLCD4 ERC2 ELOVL7	5.27e-04	850	59	9	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_100	KLHL23 GATA4	5.80e-04	13	59	2	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k2_100
ToppCell	droplet-Liver-Hepatocytes-21m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C MSX2 IRX5 ACSBG1 EYA2 IRX2	1.99e-07	178	63	6	4289e435d465b7a1490d13bf05278f4ed77d69cd
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 FLNC IRX5 ATCAY EYA2 IRX2	2.34e-07	183	63	6	99ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 FLNC IRX5 ATCAY EYA2 IRX2	2.34e-07	183	63	6	28916f0597690ff534578be2cb715b485cb1de1a
ToppCell	facs-Lung-EPCAM-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 GCLC PAX9 EYA2 MUC1 IRX2	3.10e-07	192	63	6	12096302a3a4d26e21ca04357aa557143f482155
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP\|Cerebellum / BrainAtlas - Mouse McCarroll V32	C1QL1 FLNC CPXM1 EYA2 FOXC2	2.24e-06	149	63	5	3980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell	severe_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	FRMD4A CDHR1 ATCAY KLHL23 MGAT4C	2.47e-06	152	63	5	ab5a4e47b23d16018642d4c9c7f41b30205edf73
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IRX5 GCLC ERC2 EYA2 MUC1	3.69e-06	165	63	5	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRX5 GCLC TLCD4 MUC1 IRX2	4.27e-06	170	63	5	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	droplet-Liver-Npc-21m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C MSX2 IRX5 EYA2 IRX2	4.92e-06	175	63	5	046e841811b22c39f80a9752f3223c1906de6f20
ToppCell	P28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IRX5 GCLC TLCD4 MUC1 IRX2	4.92e-06	175	63	5	8a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSX2 TLCD4 MYOM3 LOXL4 FOXC2	5.06e-06	176	63	5	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MSX1 FLNC CPXM1 EYA2 FOXC2	5.35e-06	178	63	5	cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell	droplet-Lung-nan-21m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 TLCD4 MYOM3 MUC1 IRX2	5.96e-06	182	63	5	40539ade8c3cd12b61f1cd0d493828e58282796b
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 GCLC MUC1 IRX2	6.62e-06	186	63	5	3c4994a1a7db06a61da8170e45e06aaef7896592
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 TLCD4 IRX2 ELOVL7	6.62e-06	186	63	5	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	facs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 GCLC MUC1 IRX2	6.62e-06	186	63	5	a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 TLCD4 IRX2 ELOVL7	6.62e-06	186	63	5	de88fafac51049ec1920695844d8ce8057940272
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 IRX5 ERC2 MUC1 IRX2	6.62e-06	186	63	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 TLCD4 IRX2 ELOVL7	6.62e-06	186	63	5	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 PAX9 EYA2 MUC1 IRX2	6.80e-06	187	63	5	380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCell	droplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 PAX9 EYA2 MUC1 IRX2	6.80e-06	187	63	5	5b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 PAX9 EYA2 MUC1 IRX2	6.80e-06	187	63	5	796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A ZNF608 LOXL4 EYA2 MGAT4C	6.97e-06	188	63	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 GCLC TLCD4 MUC1 IRX2	6.97e-06	188	63	5	b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 GCLC TLCD4 MUC1 IRX2	6.97e-06	188	63	5	3dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A ZNF608 LOXL4 EYA2 MGAT4C	6.97e-06	188	63	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LANCL3 IRX5 ERC2 MUC1 IRX2	6.97e-06	188	63	5	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LANCL3 IRX5 PAX9 MUC1 IRX2	6.97e-06	188	63	5	3cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCell	droplet-Lung-21m-Epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 TLCD4 MYOM3 MUC1 IRX2	7.34e-06	190	63	5	50a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 TLCD4 MUC1 IRX2 DNAH1	7.34e-06	190	63	5	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 ACSBG1 GCLC TLCD4 ELOVL7	7.53e-06	191	63	5	c21e7904e06a5c90176f935f6822dbb5a1aa6755
ToppCell	droplet-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 TLCD4 MUC1 IRX2 DNAH1	7.53e-06	191	63	5	1b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 GCLC TLCD4 MUC1 IRX2	7.72e-06	192	63	5	13e4b17d7a592604140777aca235f795df6b3f91
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 GCLC TLCD4 MUC1 IRX2	7.72e-06	192	63	5	f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 IRX5 MUC1 IRX2 ELOVL7	7.72e-06	192	63	5	b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRX5 GCLC TLCD4 MUC1 IRX2	7.72e-06	192	63	5	6244541688f85917018a057aa0b3e5972934dfbc
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 IRX5 MUC1 IRX2 ELOVL7	8.12e-06	194	63	5	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 ACSBG1 TLCD4 MTSS1 ELOVL7	8.12e-06	194	63	5	715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCF4 GCLC LOXL4 PAX9 EYA2	8.75e-06	197	63	5	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	TCF4 GCLC LOXL4 PAX9 EYA2	8.97e-06	198	63	5	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA FLNC KLHL23 ST3GAL3 MGAT4C	8.97e-06	198	63	5	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	IRX5 MOSPD2 PHPT1 MUC1 IRX2	9.19e-06	199	63	5	ccdde5d4bcc72f230a1dd2544ee7f4dfb98a5e80
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 IRX5 SAT1 MUC1 IRX2	9.19e-06	199	63	5	2e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IRX5 LOXL4 PAX9 EYA2 IRX2	9.41e-06	200	63	5	592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GCLC CDHR1 LOXL4 PAX9 EYA2	9.41e-06	200	63	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IRX5 LOXL4 PAX9 EYA2 IRX2	9.41e-06	200	63	5	8cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCell	distal-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LOXL4 PAX9 EYA2 MUC1 IRX2	9.41e-06	200	63	5	9beb128841c50241aa819261f21bf66f881ea125
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IRX5 LOXL4 PAX9 EYA2 IRX2	9.41e-06	200	63	5	61811380d9252f12f27b7ad4752380b52692677f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACSBG1 GLCE DHX38 DNAH1	3.37e-05	129	63	4	2f30b4897343586c9b49a1d2bec3007ec737085c
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 MUC1 IRX2 TSSK4	3.69e-05	132	63	4	c6bf0b4b9e33b517629faf4559a21d7ba720ee6a
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MSX2 FLNC EYA2 FOXC2	6.55e-05	153	63	4	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MSX1 FLNC EYA2 FOXC2	6.72e-05	154	63	4	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	Basal_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	GCLC CPXM1 DCLRE1A PAX9	7.42e-05	158	63	4	dd069a822e9698e6dddc155d9a5b52383f7879d5
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Thalamus / BrainAtlas - Mouse McCarroll V32	IRX5 IRX2 MGAT4C DNAH1	7.98e-05	161	63	4	0605134a342d74ae81f33700d6ddfcd6e03aeb7b
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-hematologic-erythrocytic-erythrocyte\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MSX1 MICALL2 TLCD4 IRX2	8.18e-05	162	63	4	25a11e4c6304324310b33a33331ebc812d045d4a
ToppCell	Bronchial-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MICALL2 EYA2 MGAT4C ELOVL7	8.18e-05	162	63	4	afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCell	Basal_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MSX1 TCF4 IRX5 PAX9	8.37e-05	163	63	4	679e25e5548d157d49a73057a3b5617dccda260f
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FLNC LOXL4 EYA2 FOXC2	8.78e-05	165	63	4	570483b43ccb5831feec9337b4664814431d40b1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FLNC LOXL4 EYA2 FOXC2	8.78e-05	165	63	4	2026a9a07f4d314cc05c167e491312b373468e46
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	C1QL1 LANCL3 TCF4 MTSS1	9.20e-05	167	63	4	1c1b4722c6c0eff85a9b32ca7b4e281caebf63b0
ToppCell	3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory\|blood / Manually curated celltypes from each tissue	TCF4 IFT140 ATCAY DNAH8	9.41e-05	168	63	4	2ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 EYA2 DNAH8	9.63e-05	169	63	4	3c4c3279cd72f39b5e7ff77741950ed3873c0317
ToppCell	P07-Epithelial-epithelial_progenitor_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IRX5 GCLC MUC1 IRX2	9.63e-05	169	63	4	ec23caecbb0d969307e33e9df8499ddcd1420305
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TLCD4 KLHL23 DCLRE1A FOXC2	9.63e-05	169	63	4	aec97583b23112060437b619cb429dc32f29285f
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 EYA2 DNAH8	9.63e-05	169	63	4	d6437afa298c280d202ba686338c6d8a37bd7ab7
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IRX5 GCLC MUC1 IRX2	9.63e-05	169	63	4	1a47a4892a5e6a69555f5332308503526e5422a7
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 TLCD4 MYOM3 FOXC2	1.05e-04	173	63	4	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 ST3GAL3 EYA2	1.08e-04	174	63	4	aae7ab9df5a78716034ddfd5bd47adc69912d624
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 ST3GAL3 EYA2	1.08e-04	174	63	4	d9489c4196d103ead8cb6279492bbe563a222e45
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MICALL2 GCLC CDHR1 MUC1	1.08e-04	174	63	4	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LANCL3 TLCD4 MYOM3 LOXL4	1.10e-04	175	63	4	f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LANCL3 TLCD4 MYOM3 LOXL4	1.10e-04	175	63	4	7bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell	Endothelial-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	FLNC OVOS2 MGAT4C FOXC2	1.13e-04	176	63	4	b288116a4588a1f9db9d49af92cea118937c9201
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 FLNC GATA4 CPXM1	1.18e-04	178	63	4	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 FLNC GATA4 CPXM1	1.18e-04	178	63	4	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRX5 GCLC MUC1 IRX2	1.20e-04	179	63	4	bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 SAT1 MUC1 IRX2	1.20e-04	179	63	4	7db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 GCLC EYA2	1.23e-04	180	63	4	81c7086399256260e59424b7410feec514ce8027
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACSBG1 GCLC EYA2	1.23e-04	180	63	4	5c649e2b3f5a53c0040b69df6e289fb3427ef2db
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRMD4A SAT1 MTSS1 ERC2	1.23e-04	180	63	4	810c7116007ee6668d3731e7ce1fcf697c7b24f6
ToppCell	-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	C1QL1 FLNC GATA4 CPXM1	1.25e-04	181	63	4	ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1QL1 GCLC MUC1 MGAT4C	1.28e-04	182	63	4	2ef6889321fd0104d277518d130e19143b3af41c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1QL1 GCLC MUC1 MGAT4C	1.28e-04	182	63	4	75608f80fd570da499891dc02f8649d5428b896c
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|bone_marrow / Manually curated celltypes from each tissue	LANCL3 ACSBG1 TLCD4 ELOVL7	1.28e-04	182	63	4	1a755ea44daf8447a3a1c30de7fdb9c3888bcbde
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 SAT1 MUC1 IRX2	1.28e-04	182	63	4	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 ZNF608 MTSS1 DNAH8	1.28e-04	182	63	4	ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	FRMD4A SAT1 ANO6 MTSS1	1.31e-04	183	63	4	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	Pericytes-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	C1QL1 KLHL23 CPXM1 FOXC2	1.31e-04	183	63	4	4617b18da8d699a44e4c47980197b1e7eb951470
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 IRX5 ACSBG1 IRX2	1.31e-04	183	63	4	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSX2 ACSBG1 GCLC TLCD4	1.31e-04	183	63	4	7eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAPPA2 FLNC GATA4 CPXM1	1.31e-04	183	63	4	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MSX1 FLNC EYA2 FOXC2	1.34e-04	184	63	4	235890e8b424f4386b6ea52d173d20a00898df73
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC OVOS2 MGAT4C FOXC2	1.34e-04	184	63	4	15cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 SAT1 MUC1 IRX2	1.34e-04	184	63	4	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC OVOS2 MGAT4C FOXC2	1.34e-04	184	63	4	0087c605c161fd8a39aa394f51994a04e8353bf1
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRX5 GCLC MUC1 IRX2	1.34e-04	184	63	4	49705c8fec565b16216bdf48e83e27521f52d99a
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D10C ACSBG1 GCLC EYA2	1.34e-04	184	63	4	3d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCell	facs-Lung-EPCAM-18m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 GCLC MUC1 IRX2	1.34e-04	184	63	4	04bd8ab5808fcfa923aa4d0edf6a7f88b7980122
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	LANCL3 ANO6 TLCD4 ELOVL7	1.34e-04	184	63	4	10607d7d92edcbb92d992900086b90b307421cc3
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC OVOS2 MGAT4C FOXC2	1.34e-04	184	63	4	968afa6b5ba84169377a24c150bb68749fa674d9
Disease	Hypodontia	MSX1 IRX5 PAX9	2.45e-06	14	57	3	C0020608
Disease	tooth agenesis (implicated_via_orthology)	MSX1 PAX9	3.67e-06	2	57	2	DOID:0050591 (implicated_via_orthology)
Disease	Tooth Agenesis, Familial	MSX1 IRX5	1.10e-05	3	57	2	C3489529
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	1.10e-05	3	57	2	DOID:0080096 (implicated_via_orthology)
Disease	Developmental absence of tooth	MSX1 IRX5	1.10e-05	3	57	2	C0399352
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	1.10e-05	3	57	2	DOID:0111190 (implicated_via_orthology)
Disease	Craniofacial Abnormalities	MSX1 MSX2 TCF4 IRX5 FOXC2	1.30e-05	156	57	5	C0376634
Disease	Retinitis Pigmentosa	IFT140 IRX5 CDHR1 DHX38	4.98e-05	104	57	4	C0035334
Disease	adrenoleukodystrophy (implicated_via_orthology)	ACSBG1 ELOVL7	7.65e-05	7	57	2	DOID:10588 (implicated_via_orthology)
Disease	tooth agenesis (is_implicated_in)	MSX1 PAX9	1.63e-04	10	57	2	DOID:0050591 (is_implicated_in)
Disease	Paranoia	TCF4 DNAH8	1.99e-04	11	57	2	C1456784
Disease	Oligodontia	MSX1 PAX9	2.39e-04	12	57	2	C4082304
Disease	craniosynostosis (is_implicated_in)	MSX2 FLNA	2.39e-04	12	57	2	DOID:2340 (is_implicated_in)
Disease	urate measurement	TCF4 MICALL2 HOXD13 ANO6 DHX38 MUC1 QRICH2 DNAH1	3.08e-04	895	57	8	EFO_0004531
Disease	Tetralogy of Fallot	GATA4 FOXC2	4.32e-04	16	57	2	C0039685
Disease	Congenital hernia of foramen of Morgagni	GATA4 FOXC2	6.14e-04	19	57	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	GATA4 FOXC2	6.14e-04	19	57	2	C0265700
Disease	Congenital diaphragmatic hernia	GATA4 FOXC2	7.52e-04	21	57	2	C0235833
Disease	progression free survival, ovarian serous carcinoma	MSX1 ERC2	8.26e-04	22	57	2	EFO_0004920, EFO_1001516
Disease	treatment-resistant hypertension	MSX2 TCF4 MICALL2	1.24e-03	109	57	3	EFO_1002006

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLSEMHPVDYYSSYT	ARSK	246	Q6UWY0
DMAPVFVGTPYYGYV	CDHR1	241	Q96JP9
PGTYFFTYHVLMRGG	C1QL1	171	O75973
PGDYMVTASAEGYHS	CPXM1	666	Q96SM3
APYHPDGVFMSFEGY	GLCE	166	O94923
LFDSHDSMYPGYRGP	QRICH2	936	Q9H0J4
SYVGSPYDHTPGMAG	IRX5	81	P78411
VPPYGDHTSYTMEGY	ANO6	761	Q4KMQ2
PSLFQHMGYYSSYKG	MGAT4C	306	Q9UBM8
YMTYSAAPSGYVAGH	PAX9	286	P55771
MLGFPSEVPVDSHYY	LOXL4	206	Q96JB6
IRPYMKVVTHGGYYG	ATCAY	171	Q86WG3
SPSRNYGDGTPYDHM	TCF4	66	P15884
MSEYPTYHTHGRYVP	MUC1	1206	P15941
QYYNYFHGRSPIGGM	MICALL2	101	Q8IY33
GYPMYVSPLTTSYLG	PCNX2	1826	A6NKB5
YGAAVYTYMLPSSYH	OR2T5	256	Q6IEZ7
LFYGAAMYTYVLPHS	OR2T7	241	P0C7T2
HLPDYAHYYTIGPGM	MTSS1	386	O43312
AHYYTIGPGMFPSSQ	MTSS1	391	O43312
TSPPGEGVYIYGLYM	DNAH8	4391	Q96JB1
GTYTVSYLPDMSGRY	FLNC	1596	Q14315
EYGSYMIEGTPGQPY	GCLC	96	P48506
YGGVAGVAYMLYHVS	LANCL3	66	Q6ZV70
SPMGVYSGHPEQYSA	FOXC2	36	Q99958
EQYSAGMGRSYAPYH	FOXC2	46	Q99958
YATSGPMYLSDHEGV	ERC2	56	O15083
YYGTMISMYVCPSPH	OR11L1	251	Q8NGX0
MVPSIEPYGYFYHGL	OVOS2	601	Q6IE36
AAGFPSYMGAPYDAH	IRX2	76	Q9BZI1
YGAAVYTYMLPSSYH	OR2T29	256	Q8NH02
VLSPAYYGMPGHTDT	PAPPA2	716	Q9BXP8
YMSIVESLPTYGVHY	FRMD4A	206	Q9P2Q2
GSYSSPYPAYMADVG	GATA4	156	P43694
PSISGGMYEAVNYYV	DNAH1	1886	Q9P2D7
GSARSGPVTVYPYMH	IGSF8	561	Q969P0
STATMYIIGGYYWHP	KLHL23	271	Q8NBE8
HVVMYSYYGLSALGP	ELOVL7	181	A1L3X0
EGYRVTYTPMAPGSY	FLNA	2481	P21333
GGYPVEKFVATMYHY	CRTAP	286	O75718
YTSPYQHVPGYIDMV	HOXD13	196	P35453
YAGYGLSETSGPHFM	ACSBG1	471	Q96GR2
FMYGSHYSSPGYVLF	NSMAF	386	Q92636
IYGIPYSEHSSYLEM	DCLRE1A	986	Q6PJP8
TSHSLLGMEVPYYYF	IFT140	716	Q96RY7
YDSAPSGAYGTMTYL	PHKA2	1201	P46019
PVGLYATPVGYGMYH	MSX2	251	P35548
SPYTYQMHGTTGFYQ	EYA2	131	O00167
YVSVEYLPPHMGGTD	MOSPD2	221	Q8NHP6
SSFTTDYVMYPPHLY	TATDN2	361	Q93075
VAHGPRGPTSYYYML	MRPL4	151	Q9BYD3
APVGLYTAHVGYSMY	MSX1	286	P28360
STVGYGDMYPETHLG	KCNV2	456	Q8TDN2
GFGYDMSTPNAPLHY	ST3GAL3	321	Q11203
PEGHSIVGFAMYYFT	SAT1	66	P21673
YGYSMAYGPAQHAIS	PHPT1	91	Q9NRX4
EHSSDPYHSGYEMPY	SRRT	86	Q9BXP5
PTTTAYHSLMDEYGY	TSSK4	11	Q6SA08
VYLPGYYGPHMEAVR	TBC1D10C	206	Q8IV04
SMLPHYGFMYSVYGT	TLCD4	191	Q96MV1
SLFGMGYTPDYIVYH	DHX38	1106	Q92620
AYLSPGFHYPVYGKM	ZNF608	1376	Q9ULD9
SHTNYLLMRGYYSPG	GTF3C1	1641	Q12789
GEVPSGAYGYSYMPS	WBP2	136	Q969T9
LYMGAGPVTGYHVSF	MYOM3	826	Q5VTT5