Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	SMAD_FHA_domain	KIF1B IRF4 SLC4A1AP SLMAP	2.48e-04	52	110	4	IPR008984
Domain	Guanylate_kin	MPP3 MAGI1 CACNB3	4.68e-04	26	110	3	PF00625
Domain	GK/Ca_channel_bsu	MPP3 MAGI1 CACNB3	4.68e-04	26	110	3	IPR008145
Domain	Guanylate_kin-like_dom	MPP3 MAGI1 CACNB3	4.68e-04	26	110	3	IPR008144
Domain	GuKc	MPP3 MAGI1 CACNB3	4.68e-04	26	110	3	SM00072
Domain	FHA	KIF1B SLC4A1AP SLMAP	5.85e-04	28	110	3	SM00240
Domain	Znf_MYM	PHC1 ZMYM6	7.08e-04	7	110	2	IPR010507
Domain	zf-FCS	PHC1 ZMYM6	7.08e-04	7	110	2	PF06467
Domain	FHA_DOMAIN	KIF1B SLC4A1AP SLMAP	7.92e-04	31	110	3	PS50006
Domain	FHA	KIF1B SLC4A1AP SLMAP	7.92e-04	31	110	3	PF00498
Domain	G_TR_CS	GFM2 GSPT1	1.20e-03	9	110	2	IPR031157
Domain	-	KIF1B SLC4A1AP SLMAP	1.23e-03	36	110	3	2.60.200.20
Domain	FHA_dom	KIF1B SLC4A1AP SLMAP	1.23e-03	36	110	3	IPR000253
Domain	JAMM/MPN+_dom	MYSM1 EIF3H	2.18e-03	12	110	2	IPR000555
Domain	JAB_MPN	MYSM1 EIF3H	2.18e-03	12	110	2	SM00232
Domain	JAB	MYSM1 EIF3H	2.18e-03	12	110	2	PF01398
Domain	G_TR_1	GFM2 GSPT1	2.57e-03	13	110	2	PS00301
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH12	2.99e-03	14	110	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH1 DNAH12	2.99e-03	14	110	2	IPR013602
Domain	DHC_N2	DNAH1 DNAH12	2.99e-03	14	110	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH12	2.99e-03	14	110	2	IPR011704
Domain	AAA_8	DNAH1 DNAH12	2.99e-03	14	110	2	PF12780
Domain	AAA_5	DNAH1 DNAH12	2.99e-03	14	110	2	PF07728
Domain	DHC_fam	DNAH1 DNAH12	3.43e-03	15	110	2	IPR026983
Domain	Dynein_heavy	DNAH1 DNAH12	3.43e-03	15	110	2	PF03028
Domain	Dynein_heavy_dom	DNAH1 DNAH12	3.43e-03	15	110	2	IPR004273
Domain	Guanylate_kinase_CS	MPP3 MAGI1	3.91e-03	16	110	2	IPR020590
Domain	P-loop_NTPase	MPP3 MAGI1 CACNB3 TDRD9 ZGRF1 KIF1B ABCC6 GFM2 GSPT1 DNAH1 TRANK1 DNAH12	4.22e-03	848	110	12	IPR027417
Domain	EFTu-like_2	GFM2 GSPT1	4.95e-03	18	110	2	IPR004161
Domain	GTP_EFTU_D2	GFM2 GSPT1	4.95e-03	18	110	2	PF03144
Domain	G_TR_2	GFM2 GSPT1	4.95e-03	18	110	2	PS51722
Domain	Ig_I-set	HSPG2 LRIG3 PXDNL SIGLEC1 CNTN2	5.35e-03	190	110	5	IPR013098
Domain	I-set	HSPG2 LRIG3 PXDNL SIGLEC1 CNTN2	5.35e-03	190	110	5	PF07679
Domain	TF_GTP-bd_dom	GFM2 GSPT1	5.51e-03	19	110	2	IPR000795
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	MAP4 TRIM21 SUCLG2 LGALS1 IBTK CLUH SDHA	4.49e-06	203	112	7	35012549
Pubmed	Prognostic impact of MUM1 expression by immunohistochemistry on primary mediastinal large B-cell lymphoma.	IRF4 BCL6	1.03e-05	2	112	2	21623692
Pubmed	TBC proteins: GAPs for mammalian small GTPase Rab?	TBC1D24 TBCK	1.03e-05	2	112	2	21250943
Pubmed	Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis.	MYOF APPL1	1.03e-05	2	112	2	35984564
Pubmed	Whole Exome Sequencing Identifies Novel Genetic Alterations in Patients with Pheochromocytoma/Paraganglioma.	KIF1B SDHA	1.03e-05	2	112	2	33397043
Pubmed	IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-dependent STAT3 pathway.	IRF4 BCL6	1.03e-05	2	112	2	38164749
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MPP3 HSPG2 RALGAPA2 FHIP1B NPHP4 ELAC2 TBC1D24 ITPR3 JAK3 MYOF LLGL2 IGF2R ARHGEF2 SDHA	1.31e-05	1105	112	14	35748872
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	TEF NPHP4 ATF6B ITPR3 IBTK IGF2R TGFBRAP1 SLMAP	2.82e-05	371	112	8	15747579
Pubmed	Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements.	IRF4 BCL6	3.08e-05	3	112	2	34654055
Pubmed	Immunophenotyping of diffuse large B-cell lymphoma (DLBCL) defines multiple sub-groups of germinal centre-like tumours displaying different survival characteristics.	IRF4 BCL6	3.08e-05	3	112	2	19787248
Pubmed	CD10, BCL6, and MUM1 expression in diffuse large B-cell lymphoma on FNA samples.	IRF4 BCL6	3.08e-05	3	112	2	26414904
Pubmed	Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism.	IRF4 BCL6	3.08e-05	3	112	2	24591370
Pubmed	Immunohistochemical expression of Mum-1, Oct-2 and Bcl-6 in systemic anaplastic large cell lymphomas.	IRF4 BCL6	3.08e-05	3	112	2	22158496
Pubmed	Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing.	SMO CNTN2	3.08e-05	3	112	2	19946319
Pubmed	Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4.	IRF4 BCL6	3.08e-05	3	112	2	10601358
Pubmed	Immunohistochemical Expression of CD10, BCL6 and MUM1 in Differentiating Diffuse Large B Cell Lymphoma Subtypes.	IRF4 BCL6	3.08e-05	3	112	2	29056123
Pubmed	Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation.	AMER1 LRP6	3.08e-05	3	112	2	21304492
Pubmed	Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.	IRF4 BCL6	3.08e-05	3	112	2	22464170
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	IL10RB MAP4 NCAPH2 VPS26A SLC38A2 LRIG3 MYOF IGF2R TM9SF2 LTN1 TTI1 ARHGEF2 PCCB	3.85e-05	1061	112	13	33845483
Pubmed	MUM1 expression dichotomises follicular lymphoma into predominantly, MUM1-negative low-grade and MUM1-positive high-grade subtypes.	IRF4 BCL6	6.14e-05	4	112	2	17296585
Pubmed	Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era.	IRF4 BCL6	6.14e-05	4	112	2	19656156
Pubmed	Whole exome sequencing identifies mutations in 10% of patients with familial non-syndromic cleft lip and/or palate in genes mutated in well-known syndromes.	TP63 LRP6	6.14e-05	4	112	2	29500247
Pubmed	Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteins.	IRF4 BCL6	6.14e-05	4	112	2	11342629
Pubmed	Clinicopathological and prognostic significance of BCL2, BCL6, MYC, and IRF4 copy number gains and translocations in follicular lymphoma: a study by FISH analysis.	IRF4 BCL6	6.14e-05	4	112	2	32921221
Pubmed	A role for Blimp1 in the transcriptional network controlling natural killer cell maturation.	IRF4 BCL6	6.14e-05	4	112	2	21131593
Pubmed	Lacrimal gland pleomorphic adenoma and carcinoma ex pleomorphic adenoma: genomic profiles, gene fusions, and clinical characteristics.	CRTC1 PLAG1	6.14e-05	4	112	2	24468654
Pubmed	Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.	IRF4 TRIM21	6.14e-05	4	112	2	23975864
Pubmed	Evaluation of BCL-6, CD10, CD138 and MUM-1 expression in diffuse large B-cell lymphoma patients: CD138 is a marker of poor prognosis.	IRF4 BCL6	6.14e-05	4	112	2	22994707
Pubmed	Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins.	MAGI1 KIF1B	6.14e-05	4	112	2	12097473
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	IL10RB SUCLG2 JAK3 PXDNL TTI1 SIGLEC1 GEN1	7.23e-05	313	112	7	20800603
Pubmed	Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.	KIF1B FHIP1B APPL1 SDHA	8.86e-05	72	112	4	34882091
Pubmed	The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.	SLIT1 CNTN2	1.02e-04	5	112	2	15084255
Pubmed	CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability.	IRF4 PROX1	1.02e-04	5	112	2	26999610
Pubmed	A T follicular helper cell origin for T regulatory type 1 cells.	IRF4 BCL6	1.02e-04	5	112	2	36973489
Pubmed	β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein.	AMER1 LRP6	1.02e-04	5	112	2	24265322
Pubmed	Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2.	VPS26A IGF2R	1.02e-04	5	112	2	16214895
Pubmed	Prognostic impact of activated B-cell focused classification in diffuse large B-cell lymphoma patients treated with R-CHOP.	IRF4 BCL6	1.02e-04	5	112	2	19448593
Pubmed	B-cell transcription factors Pax-5, Oct-2, BOB.1, Bcl-6, and MUM1 are useful markers for the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma.	IRF4 BCL6	1.02e-04	5	112	2	21424034
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	HSPG2 MAP4 NCAPH2 ATF6B ELAC2 SLC38A2 MYOF IGF2R TM9SF2 LTN1 TPX2 LRP6 TTI1	1.34e-04	1201	112	13	35696571
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	DNAH1 SLC38A2 IBTK APPL1 ZMYM6	1.42e-04	153	112	5	10718198
Pubmed	An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.	VPS26A MYOF TGFBRAP1	1.51e-04	32	112	3	28388416
Pubmed	Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.	IRF4 CSF3R	1.53e-04	6	112	2	25446897
Pubmed	cDNA cloning, mapping and expression of the mouse propionyl CoA carboxylase beta (pccb), the gene for human type II propionic acidaemia.	MAP4 PCCB	1.53e-04	6	112	2	11245989
Pubmed	The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.	IRF4 BCL6	1.53e-04	6	112	2	25288399
Pubmed	The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance.	SMO CNTN2	1.53e-04	6	112	2	12679031
Pubmed	LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.	CSF3R SIGLEC1	1.53e-04	6	112	2	27596364
Pubmed	Prognostic immunophenotypic biomarker studies in diffuse large B cell lymphoma with special emphasis on rational determination of cut-off scores.	IRF4 BCL6	1.53e-04	6	112	2	19925052
Pubmed	Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors.	VPS26A IGF2R	1.53e-04	6	112	2	17101778
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HSPG2 CACNB3 ZGRF1 RALGAPA2 MYOF TBCK SMO	1.81e-04	363	112	7	14691545
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH1 DNAH12	2.14e-04	7	112	2	9256245
Pubmed	Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation.	IRF4 BCL6	2.14e-04	7	112	2	25484301
Pubmed	Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis.	FANCC PROX1	2.14e-04	7	112	2	35703178
Pubmed	Mediator CDK subunits are platforms for interactions with various chromatin regulatory complexes.	CDK19 BCL6	2.14e-04	7	112	2	22668559
Pubmed	Pax6 is required for the normal development of the forebrain axonal connections.	SEMA5A CNTN2	2.14e-04	7	112	2	12397112
Pubmed	Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.	SUCLG2 SMO SDHA	2.33e-04	37	112	3	26697723
Pubmed	Characterization of murine BCAT genes: Bcat1, a c-Myc target, and its homolog, Bcat2.	CAPZA3 KLK1	2.84e-04	8	112	2	9657861
Pubmed	Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP.	KIF1B CNTN2	2.84e-04	8	112	2	19776380
Pubmed	Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons.	SLIT1 CNTN2	2.84e-04	8	112	2	17581972
Pubmed	Conserved roles for Slit and Robo proteins in midline commissural axon guidance.	SLIT1 CNTN2	2.84e-04	8	112	2	15091338
Pubmed	Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.	MAP4 ARHGEF2	2.84e-04	8	112	2	22298430
Pubmed	SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation.	BCL6 LRP6	2.84e-04	8	112	2	32820125
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BRPF3 CRTC1 TBC1D24 SLC38A2 LRIG3 IBTK TRANK1 SLMAP	3.24e-04	529	112	8	14621295
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CRTC1 NPHP4 ARHGEF2 CLUH	3.40e-04	102	112	4	9734811
Pubmed	Acquisition of neural fate by combination of BMP blockade and chromatin modification.	PHC1 PROX1	3.65e-04	9	112	2	37771660
Pubmed	MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.	AMER1 LRP6	3.65e-04	9	112	2	20128690
Pubmed	The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.	LRP6 PROX1	3.65e-04	9	112	2	16102745
Pubmed	Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma.	TRIM21 TGFBRAP1	3.65e-04	9	112	2	30836988
Pubmed	Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance.	SLIT1 CNTN2	3.65e-04	9	112	2	20631173
Pubmed	Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.	TRIM21 LGALS1 LLGL2 EIF3H	3.79e-04	105	112	4	29491746
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	HSPG2 MAP4 ELAC2 TPX2 ARHGEF2 SDHA	4.21e-04	298	112	6	30737378
Pubmed	Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections.	CNTN2 PROX1	4.55e-04	10	112	2	10707971
Pubmed	Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.	LRP6 PROX1	4.55e-04	10	112	2	14715945
Pubmed	Role of p63 and the Notch pathway in cochlea development and sensorineural deafness.	TP63 PROX1	4.55e-04	10	112	2	23589895
Pubmed	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.	RBL1 FHIP1B	4.55e-04	10	112	2	18799622
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 AMER1 MAP4 KIF1B CRTC1 LARP1B SLC38A2 NKD2 ARHGEF2 GEN1	4.79e-04	861	112	10	36931259
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MAP4 ITPR3 MYOF LTN1 ARHGEF2	5.10e-04	202	112	5	33005030
Pubmed	Absence of Nkx2-3 homeodomain transcription factor induces the formation of LYVE-1-positive endothelial cysts without lymphatic commitment in the spleen.	SIGLEC1 PROX1	5.55e-04	11	112	2	21705651
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	LRP6 CNTN2	5.55e-04	11	112	2	23968836
Pubmed	Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.	TP63 PROX1	5.55e-04	11	112	2	24038357
Pubmed	Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons.	SLIT1 PROX1	5.55e-04	11	112	2	26520399
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MAP4 LARP1B GSPT1 MYOF IBTK EIF3H PCCB GEN1 CLUH	5.71e-04	724	112	9	36232890
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	FANCC PPP1R3A TCHHL1 CEP295 EIF3H PROX1	5.92e-04	318	112	6	16919269
Pubmed	TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.	VWA5A TP63 SMO	6.05e-04	51	112	3	30478225
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	HSPG2 TRIM21 ITPR3 LRIG3 PCCB	6.62e-04	214	112	5	22199357
Pubmed	Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.	LRP6 PROX1	6.64e-04	12	112	2	24140542
Pubmed	Creation of bladder assembloids mimicking tissue regeneration and cancer.	TP63 SMO	6.64e-04	12	112	2	33328632
Pubmed	Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.	AMER1 LRP6	6.64e-04	12	112	2	22682247
Pubmed	Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.	KIF1B TRPM3	6.64e-04	12	112	2	23342162
Pubmed	A census of human transcription factors: function, expression and evolution.	IRF4 BCL6 TEF PRDM4 ATF6B MYSM1 TP63 PLAG1 ZNF541 PROX1	7.21e-04	908	112	10	19274049
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR7D4 OR4K14 OR4K1 OR4K3 OR4F15	7.35e-04	219	112	5	12213199
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	LGALS1 GSPT1 TBC1D24 IBTK IGF2R TM9SF2 LTN1 TTI1 EIF3H	7.62e-04	754	112	9	33060197
Pubmed	Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery.	SUCLG2 SDHA	7.83e-04	13	112	2	24606901
Pubmed	IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.	BBS9 SMO	7.83e-04	13	112	2	25446516
Pubmed	Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons.	SLIT1 PROX1	7.83e-04	13	112	2	31070778
Pubmed	Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling.	LRP6 PROX1	7.83e-04	13	112	2	30332639
Pubmed	Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition.	HSPG2 TP63	7.83e-04	13	112	2	33144400
Pubmed	14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing.	SMO CNTN2	7.83e-04	13	112	2	23177959
Pubmed	Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.	IGF2R PROX1	9.12e-04	14	112	2	22159122
Pubmed	DSCAM promotes axon fasciculation and growth in the developing optic pathway.	SLIT1 CNTN2	9.12e-04	14	112	2	28137836
Pubmed	Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.	LRP6 PROX1	9.12e-04	14	112	2	18985738
Cytoband	Ensembl 112 genes in cytogenetic band chr3p14	MAGI1 SUCLG2 DNAH12 SLMAP APPL1	2.53e-05	140	112	5	chr3p14
Cytoband	16p13.1	ABCC6 GSPT1	3.53e-05	4	112	2	16p13.1
Cytoband	3p14.1	MAGI1 SUCLG2	1.57e-03	24	112	2	3p14.1
Cytoband	20q11.2	RBL1 TPX2	1.99e-03	27	112	2	20q11.2
GeneFamily	Olfactory receptors, family 4	OR4C45 OR4K14 OR4S1 OR4K1 OR4K3 OR4F15	2.29e-05	129	80	6	151
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MPP3 MAGI1 CACNB3	2.02e-04	26	80	3	904
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 LRIG3 PXDNL SIGLEC1 CNTN2	7.39e-04	161	80	5	593
Coexpression	GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN	KCTD9 KIF1B BBS9 RFWD3 GSPT1 IBTK LRP6 SDHA	3.72e-07	165	106	8	M8121
Coexpression	WANG_CLIM2_TARGETS_UP	MAGI1 MAP4 RALGAPA2 GFM2 GSPT1 TGFBRAP1 TP63 GEN1	1.44e-05	270	106	8	M10334
Coexpression	GSE14308_TH1_VS_NATURAL_TREG_DN	RBL1 VPS26A TEF ATF6B TM9SF2 TGFBRAP1 TTI1	1.69e-05	199	106	7	M3381
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RBL1 ZGRF1 RFWD3 FANCC GSTCD TPX2 CEP295 GEN1	3.00e-08	193	111	8	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4 BCL6 FANCC SLC38A2 TM9SF2 VWA5A LRP6	4.68e-07	188	111	7	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	normal-na-Lymphocytic_B-B_plasma-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	HSPG2 MACC1 ZC2HC1B IRF4 TP63 CPXM1	4.34e-06	170	111	6	c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MPP3 HSPG2 SEMA5A MYOF LLGL2 TRPM3	6.22e-06	181	111	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	AMER1 TRANK1 TGFBRAP1 LTN1 SLMAP CEP295	7.27e-06	186	111	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 HSPG2 MACC1 MYOF LLGL2 SLMAP	7.73e-06	188	111	6	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RBL1 ZGRF1 RFWD3 TPX2 CEP295 GEN1	8.21e-06	190	111	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MACC1 ABCC6 ITPR3 LLGL2 ARHGEF2	8.46e-06	191	111	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MACC1 ABCC6 ITPR3 LLGL2 ARHGEF2	8.72e-06	192	111	6	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 SEMA5A BCL6 MYOF TP63 SMO	8.72e-06	192	111	6	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	MAGI1 ABCC6 LLGL2 LRP6 PLAG1 PROX1	8.98e-06	193	111	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TDRD9 KIF1B BCL6 JAK3 IGF2R CSF3R	1.07e-05	199	111	6	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	ZGRF1 SLC38A2 MYOF SIGLEC1 CNTN2 PROX1	1.07e-05	199	111	6	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SUSD4 SEMA5A SLC38A2 MYOF TP63 EIF3H	1.10e-05	200	111	6	1fa29a9f42987549a75dffeb177099458f7cca88
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SUSD4 SEMA5A SLC38A2 MYOF TP63 EIF3H	1.10e-05	200	111	6	7595eb2a8af3de879ecaa71f3d96f890e13b59ce
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	AZU1 SEMA5A RFWD3 TPX2 CEP295 SDHA	1.10e-05	200	111	6	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 AMER1 TRIM21 JAK3 ARHGEF33	1.49e-05	124	111	5	a7b7d8b14d1218194da8fcf69b4780b6e9469332
Disease	brain cancer (implicated_via_orthology)	VPS26A LLGL2 PROX1	1.17e-04	26	108	3	DOID:1319 (implicated_via_orthology)
Disease	arecaidine measurement	MYOF SLIT1	1.32e-04	5	108	2	EFO_0801112
Disease	post-operative stroke, response to surgery	BBS9 TP63	1.32e-04	5	108	2	EFO_0009951, EFO_0009956
Disease	free cholesterol change measurement, high density lipoprotein cholesterol measurement	TM9SF2 SLIT1	3.66e-04	8	108	2	EFO_0004612, EFO_0020905
Disease	diffuse large B-cell lymphoma (is_marker_for)	IRF4 BCL6	3.66e-04	8	108	2	DOID:0050745 (is_marker_for)
Disease	primary ovarian insufficiency (is_implicated_in)	BBS9 TP63	3.66e-04	8	108	2	DOID:5426 (is_implicated_in)
Disease	cancer (implicated_via_orthology)	RBL1 PHC1 LLGL2 TP63 TTI1 PROX1	4.69e-04	268	108	6	DOID:162 (implicated_via_orthology)
Disease	Fanconi anemia (is_implicated_in)	RFWD3 FANCC	5.86e-04	10	108	2	DOID:13636 (is_implicated_in)
Disease	forced expiratory volume	TDRD9 SUCLG2 BBS9 LLGL2 DNAH12 GSTCD SLMAP PLAG1 EIF3H PHIP	6.47e-04	789	108	10	EFO_0004314
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	KIF1B IGF2R	1.01e-03	13	108	2	DOID:332 (biomarker_via_orthology)
Disease	phospholipids in VLDL measurement	MPP3 IGF2R PCCB	1.34e-03	59	108	3	EFO_0022301
Disease	total lipids in VLDL measurement	MPP3 IGF2R PCCB	1.40e-03	60	108	3	EFO_0022314
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	MPP3 DNAH1 LLGL2 IGF2R PCCB	1.43e-03	224	108	5	EFO_0004530, EFO_0008317
Disease	cholesterol in very large VLDL measurement	MPP3 IGF2R PCCB	1.77e-03	65	108	3	EFO_0022230
Disease	total lipids in small VLDL	MPP3 IGF2R PCCB	1.93e-03	67	108	3	EFO_0022148
Disease	non-word reading	MACC1 SLIT1 PCCB	1.93e-03	67	108	3	EFO_0005299
Disease	Bone marrow hypocellularity	MYSM1 FANCC	1.95e-03	18	108	2	C1855710
Disease	gait measurement	CRTC1 PPP1R3A TGFBRAP1 PCCB	2.28e-03	150	108	4	EFO_0007680
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KIF1B SDHA	3.19e-03	23	108	2	C1708353

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAPPGEFVNAFDDLC	CAPZA3	21	Q96KX2
EIFGPVTCVVPFDSE	ALDH8A1	391	Q9H2A2
VVEDRLEITNCFPFP	EIF3H	71	O15372
QEDPLPTLDVFAGCQ	CDK19	336	Q9BWU1
VQCPPESFDVILDEN	CACNB3	326	P54284
LEPGVVQGLFPCVDE	ARHGEF2	271	Q92974
EEPFQAPALFENCSP	ARHGEF33	631	A8MVX0
RVTFEEGPFPCNFVL	CPXM1	686	Q96SM3
IPEVCFANTVFLEPI	BRPF3	296	Q9ULD4
APQVPCFEETFQAPR	AMER1	211	Q5JTC6
ELNCEEPVLGISPTF	HSPG2	231	P98160
LPLEPGGCIDFQTEN	RFWD3	631	Q6PCD5
QEVLQPFCDFPEIVD	JAK3	286	P52333
IVFPVPGICQFLTEE	ITPR3	2136	Q14573
DNPPIFLIGFCEILQ	LTN1	1041	O94822
CVAQEPSLLEFFLQP	FHIP1B	186	Q8N612
QAQGIEHFFCDVPPV	OR10W1	161	Q8NGF6
VLFVCEGEPFIDPQT	KCTD9	61	Q7L273
EREINSTNFGECPIP	MAGI1	821	Q96QZ7
EDTNFCFQPEQVVDP	MAP4	121	P27816
IEPENFSFPDDLQCV	KLK1	161	P06870
VRFEPGFQPFVLVQC	LLGL2	571	Q6P1M3
AVFPFQPGSVAEVCI	LGALS1	76	P09382
FVELTEDIGPQFPCQ	NMUR2	371	Q9GZQ4
FQVTLCFGEEFPDPQ	IRF4	381	Q15306
FVCDDFPKPQITVQP	LRIG3	491	Q6UXM1
FGNPEEFVIVERTPQ	IBTK	1326	Q9P2D0
RASSPCPEFEQFQIV	KIF1B	1656	O60333
CPEFEQFQIVPAVET	KIF1B	1661	O60333
TPIQFDIISPVCEDQ	APPL1	451	Q9UKG1
LFIAQLPFCGPNVID	OR4C45	156	A6NMZ5
AFTVDLPFCGPNEVD	OR4K1	161	Q8NGD4
PNEVDSFFCDLPLVI	OR4K1	171	Q8NGD4
AFTVNLPFCGPNEVD	OR4K3	161	Q96R72
PNEVDSFFCDLPLVI	OR4K3	171	Q96R72
GPNEVDSFFCDLPLV	OR4K14	171	Q8NGD5
TVQLPFCGPNEIDNF	OR4S1	161	Q8NGB4
GAQPPIELLRQFFDC	DNAH12	1971	Q6ZR08
PQQFTCFTGEIDCIP	LRP6	1251	O75581
GEVQPESACENPAFF	GDPD4	256	Q6W3E5
VFVVDLPFCGPNIFD	OR4F15	161	Q8NGB8
EVFVPENNRPGDLLC	PCDHGC4	461	Q9Y5F7
EEQVLIFACLVPGFP	RALGAPA2	146	Q2PPJ7
EGPFREDQCPLQVAL	NKD2	56	Q969F2
EEEILPGFILCDPNN	GSPT1	371	P15170
VQPPLELTCDQFTFE	BBS9	461	Q3SYG4
CETQNVGPGEPRDIF	NPHP4	1181	O75161
GNCLFPLLEEDPNIF	METTL6	91	Q8TCB7
CEDEEVTFQPGFSPQ	PPP1R3A	26	Q16821
CDAFNIPLITFVDVP	PCCB	381	P05166
GTEIPHFFCEPAQVL	OR7D4	171	Q8NG98
ICSVQPIDLNFVDEP	TP63	66	Q9H3D4
VEEFNCQSPRITFEP	PXDNL	226	A1KZ92
FEGVEIPLVPSCAVF	DNAH1	1666	Q9P2D7
CEVPGINIFPSADQE	CRTC1	216	Q6UUV9
CHGREPQEILQPEFF	FANCC	206	Q00597
QVTLECFAFGNPVPR	CNTN2	256	Q02246
VINLDPEINPEGFCI	BCL6	71	P41182
SQEDDCVFGPLLNFP	CSF3R	806	Q99062
VNITFCPVDDTIIGP	IL10RB	101	Q08334
HLFDFCVQVEPPNGE	MACC1	481	Q6ZN28
IPDGFENIPEQLSCE	GEN1	621	Q17RS7
FPRFVNVTVTPEDQC	AZU1	166	P20160
VCSEQAEPSFPFQVA	CEP295	986	Q9C0D2
NEFPLCSLPEGVDQE	POLI	516	Q9UNA4
LCEVPGVEEQSDPLF	GSTCD	356	Q8NEC7
SQLIDCPEFVPGQAF	LARP1B	311	Q659C4
FFCTSQDIPPENELL	PRDM4	511	Q9UKN5
EDRAIPCQEAGLPFQ	MPP3	241	Q13368
ETDDGVPCVFPFIFN	IGF2R	1896	P11717
CPQPLFEDPEFTQEN	RTP3	96	Q9BQQ7
AGVEIPEPVFFCTIE	GFM2	481	Q969S9
PCQDLEFVQFHPTGI	SDHA	286	P31040
EIPCQFLELPFQALE	TDRD9	996	Q8NDG6
SVVENVCFGQELDPP	ABCC6	706	O95255
PTCEEVIFPNNFETG	RBL1	586	P28749
CFGDVIIPNPLDTFG	PROX1	411	Q92786
CVEVDVNFNPDPADL	TEF	176	Q10587
ESRPCVFDSNFIPEV	SEMA5A	936	Q13591
TQLFRCPEQDVPFDG	ATF6B	46	Q99941
PFAELVAGQPAFEVC	NCAPH2	536	Q6IBW4
IFSPGVRFPESCQDE	CLUH	721	O75153
EPVDFLDPFTCNVSV	PLAG1	246	Q6DJT9
GTGECFVFRLQPEVQ	TBC1D24	426	Q9ULP9
CQENELFPGPVRIFV	TMEM92	46	Q6UXU6
EVNPFGETPEGQVVC	SUCLG2	241	Q96I99
ENPVSGDPFCVEVCI	TGFBRAP1	126	Q8WUH2
EIPFTCPTGGNFLEE	ZNF132	261	P52740
FVVVECPDESFIQPI	ELAC2	306	Q9BQ52
LIFQCEDSEPFRQPV	PHIP	1331	Q8WWQ0
FQVPCPVEAALIINE	SLC38A2	241	Q96QD8
VFADQIDPPCGQNET	TRPM3	1081	Q9HCF6
ESPPCEILSGDIIQF	SLMAP	91	Q14BN4
FDDLQVCADPGIPEN	SUSD4	51	Q5VX71
PEDQPSNTCGEFIFL	VWA5A	271	O00534
FVIQEGAEPFPVGCS	PHC1	741	P78364
CIFSFPADVEVPDGI	SIGLEC1	41	Q9BZZ2
PICTLPNFLFEDGES	TBCK	351	Q8TEA7
QVPPCQVGIFLDYEA	TRIM21	401	P19474
PDRFPEGCTNEVQNI	SMO	171	Q99835
PFLADGNQELFPCEV	ZC2HC1B	6	Q5TFG8
DVEDGQRFCNPGFPI	TM9SF2	166	Q99805
LEGLSQVFSDCFPPE	ZMYM6	1191	O95789
GFFGPICEIDIVLND	VPS26A	6	O75436
FSPSFQINPEVLCEE	ZGRF1	196	Q86YA3
LIQGEFGDFFQPCVL	TCHHL1	36	Q5QJ38
IQQVEVDPSFPEDCL	TRANK1	696	O15050
QIPLQDVAFPDFRCE	SLIT1	706	O75093
TPEEAFGVLRPVCVQ	TTI1	6	O43156
QEPQVFGTEFCKPLR	ZNF541	871	Q9H0D2
QIPEARTVEICPFSF	TPX2	526	Q9ULW0
FCPPAPDQIDRFVQI	DUSP23	66	Q9BVJ7
PQPDCGDFRSLQEEQ	SLC4A1AP	121	Q9BWU0
QFRELPDSVPQECTV	MYOF	1541	Q9NZM1
LIPCNFFSEEKQEPF	MYSM1	561	Q5VVJ2