Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEE POTEF ACTB ACTG1	8.11e-08	11	81	4	GO:0098973
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEE POTEF ACTB ACTG1	8.29e-06	32	81	4	GO:0099186
GeneOntologyMolecularFunction	cysteine-S-conjugate N-acetyltransferase activity	NAT8B NAT8	1.63e-05	2	81	2	GO:0047198
GeneOntologyMolecularFunction	structural constituent of synapse	POTEE POTEF ACTB ACTG1	2.50e-05	42	81	4	GO:0098918
GeneOntologyMolecularFunction	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8B NAT8	2.41e-04	6	81	2	GO:0004468
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEE POTEF ACTB ACTG1	7.41e-06	31	84	4	GO:0098974
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEE POTEF ACTB ACTG1	1.22e-05	35	84	4	GO:0099188
GeneOntologyBiologicalProcess	peptidyl-lysine N6-acetylation	NAT8B NAT8	1.64e-05	2	84	2	GO:0018003
GeneOntologyBiologicalProcess	regulation of transepithelial transport	ACTB ACTG1	9.78e-05	4	84	2	GO:0150111
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEE POTEF ACTB ACTG1	7.63e-06	32	83	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEE POTEF ACTB ACTG1	7.63e-06	32	83	4	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEE POTEF ACTB ACTG1	3.04e-05	45	83	4	GO:1902562
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEE POTEF ACTB ACTG1 ING4	3.64e-05	94	83	5	GO:0000123
GeneOntologyCellularComponent	late recombination nodule	NAT8B NAT8	4.66e-05	3	83	2	GO:0005715
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEE POTEF ACTB ACTG1 ING4	5.90e-05	104	83	5	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEE POTEF ACTB ACTG1 ING4	7.39e-05	109	83	5	GO:1902493
GeneOntologyCellularComponent	recombination nodule	NAT8B NAT8	9.30e-05	4	83	2	GO:0005713
GeneOntologyCellularComponent	tight junction	USP53 SIPA1L3 ACTB ASH1L WNK4	2.32e-04	139	83	5	GO:0070160
GeneOntologyCellularComponent	dense body	ACTB ACTG1	3.23e-04	7	83	2	GO:0097433
GeneOntologyCellularComponent	apical junction complex	USP53 ACTB ASH1L ACTG1 WNK4	4.18e-04	158	83	5	GO:0043296
GeneOntologyCellularComponent	postsynaptic actin cytoskeleton	ACTB ACTG1	2.55e-03	19	83	2	GO:0098871
GeneOntologyCellularComponent	blood microparticle	POTEE POTEF ACTB ACTG1	2.60e-03	144	83	4	GO:0072562
GeneOntologyCellularComponent	plasma membrane signaling receptor complex	TRBV29-1 TRA HTR3E ITGAL TRAV38-2DV8 TRAV38-1	2.70e-03	350	83	6	GO:0098802
GeneOntologyCellularComponent	actin filament	POTEE POTEF ACTB ACTG1	2.74e-03	146	83	4	GO:0005884
Domain	Actin_CS	POTEE POTEF ACTB ACTG1	4.44e-07	16	76	4	IPR004001
Domain	ACTINS_2	POTEE POTEF ACTB ACTG1	5.79e-07	17	76	4	PS00432
Domain	Actin/actin-like_CS	POTEE POTEF ACTB ACTG1	7.42e-07	18	76	4	IPR020902
Domain	ACTINS_ACT_LIKE	POTEE POTEF ACTB ACTG1	9.37e-07	19	76	4	PS01132
Domain	Actin	POTEE POTEF ACTB ACTG1	7.33e-06	31	76	4	IPR004000
Domain	Actin	POTEE POTEF ACTB ACTG1	7.33e-06	31	76	4	PF00022
Domain	ACTIN	POTEE POTEF ACTB ACTG1	7.33e-06	31	76	4	SM00268
Domain	AWS	ASH1L NSD3	1.62e-04	5	76	2	SM00570
Domain	AWS	ASH1L NSD3	1.62e-04	5	76	2	PS51215
Domain	AWS_dom	ASH1L NSD3	1.62e-04	5	76	2	IPR006560
Domain	ACTINS_1	ACTB ACTG1	4.50e-04	8	76	2	PS00406
Domain	Post-SET_dom	ASH1L NSD3	1.89e-03	16	76	2	IPR003616
Domain	PostSET	ASH1L NSD3	1.89e-03	16	76	2	SM00508
Domain	POST_SET	ASH1L NSD3	1.89e-03	16	76	2	PS50868
Domain	Zinc_finger_PHD-type_CS	ASH1L ING4 NSD3	2.36e-03	65	76	3	IPR019786
Domain	PHD	ASH1L ING4 NSD3	3.54e-03	75	76	3	PF00628
Domain	Acetyltransf_1	NAT8B NAT8	3.91e-03	23	76	2	PF00583
Domain	Znf_PHD-finger	ASH1L ING4 NSD3	4.10e-03	79	76	3	IPR019787
Domain	GNAT	NAT8B NAT8	4.61e-03	25	76	2	PS51186
Domain	GNAT_dom	NAT8B NAT8	4.61e-03	25	76	2	IPR000182
Domain	PHD	ASH1L ING4 NSD3	5.72e-03	89	76	3	SM00249
Domain	Znf_PHD	ASH1L ING4 NSD3	6.09e-03	91	76	3	IPR001965
Domain	ZF_PHD_2	ASH1L ING4 NSD3	6.85e-03	95	76	3	PS50016
Domain	ZF_PHD_1	ASH1L ING4 NSD3	7.06e-03	96	76	3	PS01359
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEE POTEF ACTB ACTG1	4.66e-08	15	86	4	16824795
Pubmed	Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.	IGHV1-69-2 IGHV1-38-4 IGHV1-69D	5.07e-07	7	86	3	23541343
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	USP53 NCOA6 PTPN13 DRG2 IKBKE POTEF SIPA1L3 GRB10 ARHGEF17 WNK4 PHLDB2 NSD3	1.40e-06	861	86	12	36931259
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEE KRT34 POTEF ACTB ACTG1	4.21e-06	96	86	5	23580065
Pubmed	Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.	ACTB ACTG1	6.04e-06	2	86	2	19638415
Pubmed	Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.	ACTB ACTG1	6.04e-06	2	86	2	21778137
Pubmed	The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides.	NAT8B NAT8	6.04e-06	2	86	2	25301944
Pubmed	De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.	ACTB ACTG1	6.04e-06	2	86	2	22366783
Pubmed	Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.	ACTB ACTG1	6.04e-06	2	86	2	3335520
Pubmed	Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.	ACTB ACTG1	6.04e-06	2	86	2	9288906
Pubmed	High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.	ACTB ACTG1	6.04e-06	2	86	2	1577857
Pubmed	Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.	ACTB ACTG1	6.04e-06	2	86	2	32588558
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome.	ACTB ACTG1	6.04e-06	2	86	2	27625340
Pubmed	Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors.	ACTB PDE10A	6.04e-06	2	86	2	32610130
Pubmed	Baraitser-Winter Cerebrofrontofacial Syndrome	ACTB ACTG1	6.04e-06	2	86	2	26583190
Pubmed	Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.	ACTB ACTG1	6.04e-06	2	86	2	32326615
Pubmed	M1 muscarinic acetylcholine receptor-mediated inhibition of GABA release from striatal medium spiny neurons onto cholinergic interneurons.	ACTB PDE10A	6.04e-06	2	86	2	33270289
Pubmed	Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.	ACTB ACTG1	6.04e-06	2	86	2	23756437
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEE POTEF	6.04e-06	2	86	2	19669888
Pubmed	Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.	ACTB ACTG1	6.04e-06	2	86	2	8482333
Pubmed	Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.	ACTB ACTG1	6.04e-06	2	86	2	3221869
Pubmed	Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.	ACTB ACTG1	6.04e-06	2	86	2	29265728
Pubmed	The role of N-acetyltransferase 8 in mesenchymal stem cell-based therapy for liver ischemia/reperfusion injury in rats.	NAT8B NAT8	6.04e-06	2	86	2	25057902
Pubmed	Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.	ACTB ACTG1	6.04e-06	2	86	2	22246323
Pubmed	Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity.	ACTB PDE10A	6.04e-06	2	86	2	28167674
Pubmed	Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.	ACTB ACTG1	6.04e-06	2	86	2	2837653
Pubmed	Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.	ACTB ACTG1	6.04e-06	2	86	2	32349449
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.	ACTB ACTG1	6.04e-06	2	86	2	32506774
Pubmed	Inhibition of the dorsomedial striatal direct pathway is essential for the execution of action sequences.	ACTB PDE10A	6.04e-06	2	86	2	37553985
Pubmed	Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism.	NAT8B NAT8	6.04e-06	2	86	2	33846551
Pubmed	Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.	ACTB ACTG1	6.04e-06	2	86	2	20847274
Pubmed	Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.	ACTB ACTG1	6.04e-06	2	86	2	21502360
Pubmed	The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.	ACTB ACTG1	6.04e-06	2	86	2	6686106
Pubmed	Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.	ACTB ACTG1	6.04e-06	2	86	2	213279
Pubmed	The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.	ACTB ACTG1	6.04e-06	2	86	2	33334799
Pubmed	Striatonigral direct pathway activation is sufficient to induce repetitive behaviors.	ACTB PDE10A	6.04e-06	2	86	2	28939413
Pubmed	β-Actin specifically controls cell growth, migration, and the G-actin pool.	ACTB ACTG1	6.04e-06	2	86	2	21900491
Pubmed	Functional proteomics mapping of a human signaling pathway.	SCYL2 NCOA6 AP2A2 ACTB ASH1L ACTG1 TDG PLIN3 RYR2	1.60e-05	591	86	9	15231748
Pubmed	Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.	ACTB ACTG1	1.81e-05	3	86	2	9245787
Pubmed	Impact of altered actin gene expression on vinculin, talin, cell spreading, and motility.	ACTB ACTG1	1.81e-05	3	86	2	7646816
Pubmed	Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.	ACTB ACTG1	1.81e-05	3	86	2	19008859
Pubmed	Identification of optogenetically activated striatal medium spiny neurons by Npas4 expression.	ACTB PDE10A	1.81e-05	3	86	2	23300775
Pubmed	Angiostatin and plasminogen share binding to endothelial cell surface actin.	ACTB ACTG1	1.81e-05	3	86	2	15746964
Pubmed	Interaction of Receptor-Binding Domain of the SARS-CoV-2 Omicron Variant with hACE2 and Actin.	ACTB ACTG1	1.81e-05	3	86	2	39195208
Pubmed	Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses.	ACTB ACTG1	1.81e-05	3	86	2	27840001
Pubmed	Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.	ACTB ACTG1	1.81e-05	3	86	2	22403730
Pubmed	Functional molecular complexes of human N-formyl chemoattractant receptors and actin.	ACTB ACTG1	1.81e-05	3	86	2	8228254
Pubmed	CTGF/Hcs24 interacts with the cytoskeletal protein actin in chondrocytes.	ACTB ACTG1	1.81e-05	3	86	2	12470643
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEE POTEF	1.81e-05	3	86	2	17101985
Pubmed	Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.	NAT8B NAT8	1.81e-05	3	86	2	24556617
Pubmed	Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.	ACTB ACTG1	1.81e-05	3	86	2	6865942
Pubmed	Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation.	ACTB ACTG1	1.81e-05	3	86	2	17192268
Pubmed	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.	NAT8B NAT8	1.81e-05	3	86	2	11397015
Pubmed	Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.	NAT8B NAT8	1.81e-05	3	86	2	19011241
Pubmed	L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.	ACTB ACTG1	3.61e-05	4	86	2	12082080
Pubmed	β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance.	ACTB ACTG1	3.61e-05	4	86	2	20976199
Pubmed	Functional analyses of placental protein 13/galectin-13.	ACTB ACTG1	3.61e-05	4	86	2	15009185
Pubmed	The formin-homology-domain-containing protein FHOD1 enhances cell migration.	ACTB ACTG1	3.61e-05	4	86	2	12665555
Pubmed	Molecular cloning and functional characterization of mouse coactosin-like protein.	ACTB ACTG1	3.61e-05	4	86	2	11785969
Pubmed	IQGAP1 regulates reactive oxygen species-dependent endothelial cell migration through interacting with Nox2.	ACTB ACTG1	3.61e-05	4	86	2	16179592
Pubmed	Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes.	ACTB ACTG1	3.61e-05	4	86	2	6893015
Pubmed	The proline-rich domain of tau plays a role in interactions with actin.	ACTB ACTG1	3.61e-05	4	86	2	19895707
Pubmed	Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation.	NAT8B NAT8	3.61e-05	4	86	2	22267734
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	POTEE AP2A2 SIPA1L3 ACTB NOL11 ACTG1 MSH3 CPSF3 PHLDB2	3.79e-05	660	86	9	32780723
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KNTC1 POTEE AP2A2 TTC16 KRT34 POTEF SIPA1L3 ACTB ASH1L ACTG1 PDE10A C2orf78 RYR2	5.27e-05	1442	86	13	35575683
Pubmed	HIV-1 Gag-RNA interaction occurs at a perinuclear/centrosomal site; analysis by confocal microscopy and FRET.	ACTB ACTG1	6.01e-05	5	86	2	16101678
Pubmed	Microtubule associated protein MAP1A is an actin-binding and crosslinking protein.	ACTB ACTG1	6.01e-05	5	86	2	7820861
Pubmed	Monitoring of S protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute respiratory syndrome coronavirus.	ACTB ACTG1	6.01e-05	5	86	2	22915798
Pubmed	Nonredundant roles of cytoplasmic β- and γ-actin isoforms in regulation of epithelial apical junctions.	ACTB ACTG1	6.01e-05	5	86	2	22855531
Pubmed	Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.	ASH1L NSD3	6.01e-05	5	86	2	39390582
Pubmed	Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance.	ING4 TDG	6.01e-05	5	86	2	26544625
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	SCYL2 DENND5B OR2T29 ACTB ACTG1 OR2T5	6.67e-05	277	86	6	30745168
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTB ACTG1	9.01e-05	6	86	2	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTB ACTG1	9.01e-05	6	86	2	1540415
Pubmed	Mammalian CAP interacts with CAP, CAP2, and actin.	ACTB ACTG1	9.01e-05	6	86	2	8761950
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTB ACTG1	9.01e-05	6	86	2	11709093
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTB ACTG1	9.01e-05	6	86	2	9971772
Pubmed	A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.	TP53BP1 MEOX2	9.01e-05	6	86	2	18676810
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTB ACTG1	9.01e-05	6	86	2	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTB ACTG1	9.01e-05	6	86	2	12009869
Pubmed	FISH localization of human cytoplasmic actin genes ACTB to 7p22 and ACTG1 to 17q25 and characterization of related pseudogenes.	ACTB ACTG1	9.01e-05	6	86	2	8941379
Pubmed	Rapid, redox-mediated mechanical susceptibility of the cortical microtubule lattice in skeletal muscle.	ACTB ACTG1	9.01e-05	6	86	2	33002761
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTB ACTG1	9.01e-05	6	86	2	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTB ACTG1	9.01e-05	6	86	2	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTB ACTG1	9.01e-05	6	86	2	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTB ACTG1	9.01e-05	6	86	2	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTB ACTG1	9.01e-05	6	86	2	23017337
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTB ACTG1	9.01e-05	6	86	2	10074138
Pubmed	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.	ACTB ACTG1	9.01e-05	6	86	2	12679033
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTB ACTG1	9.01e-05	6	86	2	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTB ACTG1	9.01e-05	6	86	2	9841925
Pubmed	The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.	POTEE POTEF ACTB ACTG1	1.14e-04	100	86	4	21800051
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTB ACTG1	1.26e-04	7	86	2	17504171
Pubmed	Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine.	AP2A2 MEOX2	1.26e-04	7	86	2	20351096
Pubmed	Synaptic, transcriptional and chromatin genes disrupted in autism.	DSCAM ASH1L	1.26e-04	7	86	2	25363760
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTB ACTG1	1.26e-04	7	86	2	22535526
Pubmed	A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.	NCOA6 TP53BP1	1.26e-04	7	86	2	19433796
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTB ACTG1	1.26e-04	7	86	2	22465675
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTB ACTG1	1.26e-04	7	86	2	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTB ACTG1	1.26e-04	7	86	2	22640593
Interaction	ZSCAN26 interactions	TDG MSH3 PLIN3 KRTAP10-4 KRTAP10-3	2.85e-06	59	76	5	int:ZSCAN26
Interaction	EFNA3 interactions	POTEE ACTB ASH1L ARHGEF17 MEOX2 KRTAP10-3	3.32e-06	108	76	6	int:EFNA3
Interaction	ACBD4 interactions	PEX3 ACBD5 MEOX2	2.27e-05	15	76	3	int:ACBD4
Interaction	ACTG2 interactions	POTEE POTEF ACTB ACTG1	3.48e-05	49	76	4	int:ACTG2
Interaction	MORF4L2 interactions	DSCAM ACTB ASH1L ACTG1 MBD6 MEOX2	4.14e-05	168	76	6	int:MORF4L2
GeneFamily	Actins	ACTB ACTG1	1.72e-04	6	62	2	929
GeneFamily	Olfactory receptors, family 2	OR2T29 OR2T7 OR2T5 OR2Z1	6.10e-04	113	62	4	149
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEE POTEF	8.81e-04	13	62	2	685
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PIEZO2 CD7 TRA SCARA5 RYR2 MEOX2	2.16e-06	195	86	6	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	COVID-19_Mild-PLT_3\|World / Disease Group and Platelet Clusters	FAM106A ACTB ACTG1 PDE10A ITGAL	9.79e-06	147	86	5	9d3271aa735ddb6f32ab864d7afcfb0f8754383b
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 DSCAM ACTB ACTG1 PHLDB2	2.89e-05	184	86	5	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 DSCAM ACTB ACTG1 PHLDB2	2.89e-05	184	86	5	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	TYW1B IKBKE ING4 TRAV38-2DV8 TRMT2B	3.04e-05	186	86	5	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB ELAPOR1 GRB10 ACTG1 ZDBF2	3.28e-05	189	86	5	ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN13 PIEZO2 PDE10A RYR2 MEOX2	3.28e-05	189	86	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB ELAPOR1 GRB10 ACTG1 ZDBF2	3.36e-05	190	86	5	db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP53 PIEZO2 RYR2 PHLDB2 MEOX2	3.71e-05	194	86	5	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	BLOOD--(1)_EM_CTLs\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TTC16 TRA MBL2 ACTB ITGAL	3.71e-05	194	86	5	66583c6cff3814902d6babdea3a2ae962decde65
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 PIEZO2 SCARA5 PHLDB2 GLP2R	3.81e-05	195	86	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytotoxic_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CD7 ATP8A1 TTC16 ACTB ITGAL	3.81e-05	195	86	5	730c613cf6f4d16ca51fd44de1f5a883f615c5c5
ToppCell	ILEUM-inflamed-(1)_Cytotoxic_T_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD7 ATP8A1 TTC16 TRA ACTB	3.90e-05	196	86	5	42d807605c6103fc80f038f4a351e89981533669
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP53 PIEZO2 SCARA5 RYR2 MEOX2	3.90e-05	196	86	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	(1)_T_cells-(1)_T_CD8_CytT\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	TTC16 MBL2 ACTB ACTG1 ITGAL	3.90e-05	196	86	5	3a4ba9ca84ce6b35038765da8c55812587b58bc2
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 PIEZO2 SCARA5 RYR2 MEOX2	3.90e-05	196	86	5	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	USP53 PIEZO2 RYR2 PHLDB2 MEOX2	4.00e-05	197	86	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRY ACTB ARHGEF17 RYR2 PHLDB2	4.09e-05	198	86	5	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	remission-NK\|World / disease stage, cell group and cell class	STK10 CD7 ACTB ACTG1 ITGAL	4.09e-05	198	86	5	383ed78164ad37826100d3de6c3cc14f62e01813
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POTEE ACTB SMOX ARHGEF17 WNK4	4.09e-05	198	86	5	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 PIEZO2 SCARA5 RYR2 MEOX2	4.09e-05	198	86	5	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	PIEZO2 ACTG1 PDE10A RYR2 MEOX2	4.19e-05	199	86	5	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	af43f6d0e03b77f5eca1762e7b2be1d244d47664
ToppCell	remission-CD8+_Tem\|World / disease stage, cell group and cell class	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	0ebf0dda91fc7adb9ea69734ad9dcc65d0082c6d
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD8+_Tem\|COVID-19_Convalescent / Disease, condition lineage and cell class	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	7c8a5465b478f430495942151c36020023d9bac9
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIEZO2 SCARA5 RYR2 PHLDB2 MEOX2	4.29e-05	200	86	5	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	63077e1f801f1c08bd339f5517f5781da240c04f
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	f0452dc1056b5ea492e61b20bb52815a5d2f705e
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD7 TTC16 ITGAL TRAV38-2DV8 TRAV38-1	4.29e-05	200	86	5	dc719c7f0ffee0db4f56f1991e47974dc7bef11b
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	024eafabb576bfb835452def941237a35eebb912
ToppCell	remission-CD8+_Tem\|remission / disease stage, cell group and cell class	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	f1e4b8fcb422727f665f22b48f34bee23f0fad52
ToppCell	Caecum-(1)_T_cell-(17)_gd_T\|Caecum / shred on region, Cell_type, and subtype	CD7 ATP8A1 ACTB ACTG1 MSH3	4.29e-05	200	86	5	2aaa6b37e9f8d95de53f284a42a3ac14e6351b40
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	64c2399c78e4ce0f05893d856bf90b1d3f5dba03
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIEZO2 SCARA5 RYR2 PHLDB2 MEOX2	4.29e-05	200	86	5	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	94d4f690bf5b87866c0840715396d360b1737d11
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-CD8+_Tem\|COVID-19_Convalescent / Disease group, lineage and cell class	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	3f00839697183a1066548930b9ec3664b3568afc
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD7 TTC16 ITGAL TRAV38-1 C2orf78	4.29e-05	200	86	5	b76f000582b38f4c61b44081eba9ae213382cb6f
ToppCell	Caecum-T_cell-gd_T\|Caecum / Region, Cell class and subclass	CD7 ATP8A1 ACTB ACTG1 MSH3	4.29e-05	200	86	5	eaacd14b6d4a1c7d52deab110ed3a6c7d3dc1f8e
ToppCell	COVID-19_Convalescent-CD8+_Tem\|COVID-19_Convalescent / Disease condition and Cell class	STK10 TTC16 ACTB ACTG1 ITGAL	4.29e-05	200	86	5	1cf2234d5add07e1cd560ca3efa8aafd0851921d
ToppCell	(17)_gd_T\|World / shred on Cell_type and subtype	CD7 ATP8A1 ACTB ACTG1 MSH3	4.40e-05	201	86	5	7fcfe48758acf07cb3dda939ce589ae1518e41c9
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KNTC1 CD7 ITGAL	1.47e-04	53	86	3	2147787ed3de18b49f51a8518984c7b6ba9a8cef
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KNTC1 TTC16 TBC1D9 GLP2R	2.14e-04	152	86	4	5ce8920aedd39a4daf7082153b5e213707c14227
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD7 ACTB ITGAL WNK4	2.25e-04	154	86	4	886e7cd01cb48ca3e97debeea2b1f100b09d47e6
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|367C / Donor, Lineage, Cell class and subclass (all cells)	POTEE CD7 ATP8A1 TTC16	2.25e-04	154	86	4	a39877cdf7b441b5c953f744ed30f1d5acf4ea19
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	POTEE ATP8A1 TTC16 ASH1L	2.37e-04	156	86	4	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	PND07-28-samps\|World / Age Group, Lineage, Cell class and subclass	STK10 ACTB ITGAL TBC1D9	2.43e-04	157	86	4	a2005768a6d268879e3fd6dbd8cf674dc98be587
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	CD7 ATP8A1 TTC16 ITGAL	2.61e-04	160	86	4	ab633295cb4de88fdbc076295e1352769f47cc00
ToppCell	Mild-MAIT\|Mild / Disease group and Cell class	TEAD2 FRY PTPN13 SMOX	2.67e-04	161	86	4	0c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 FRY PIEZO2 ARHGEF17	2.67e-04	161	86	4	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FAM106A TTC16 TRAV38-2DV8 TRAV38-1	2.73e-04	162	86	4	4b9f80f701dcbb2508f497095cb8a7a2ca51cb5e
ToppCell	T_cells-Tph_and_Tfh\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PTPN13 CD7 ELAPOR1 ITGAL	2.73e-04	162	86	4	146058f2d60846376078916055d08f68562e3a7c
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B2\|390C / Donor, Lineage, Cell class and subclass (all cells)	CD7 ACTB ACBD5 ITGAL	2.80e-04	163	86	4	036e65de0f8fc391f3e4d299bf4c05ee5c3b5a37
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD8 CD7 DSCAM ITGAL	2.93e-04	165	86	4	e24621c8d4dbafb407033d832fe9337f13feae34
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM SIPA1L3 ZDBF2 RYR2	2.93e-04	165	86	4	6d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM SIPA1L3 ZDBF2 RYR2	2.93e-04	165	86	4	84f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell	ILEUM-non-inflamed-(1)_Cytotoxic_T_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TTC16 TRA ACTB ITGAL	3.00e-04	166	86	4	67f9d88329724cdda11bf76e964f66456ff6fb46
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MSH3 RFXAP RYR2 CES2	3.14e-04	168	86	4	c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MSH3 RFXAP RYR2 CES2	3.14e-04	168	86	4	83b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN13 CD7 SCARA5 PEX3	3.14e-04	168	86	4	1dfe87129fdf4cef71dbc17cf39692f0b8dc3345
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FNDC7 CD7 ZDBF2 TBC1D9	3.21e-04	169	86	4	b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCell	-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	PIEZO2 CD7 TRA TRAV38-1	3.28e-04	170	86	4	601630644f09133ee4c5e64499460b55cf3e80a0
ToppCell	droplet-Liver-Npc\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK10 CD7 ACTB ITGAL	3.28e-04	170	86	4	09c836840216905d545a25a4fc1bbd0699576c77
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK10 TRBV29-1 TTC16 ITGAL	3.36e-04	171	86	4	187b396059f8802265f54bad2b4882cebb809419
ToppCell	droplet-Liver-Npc-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK10 CD7 ACTB ITGAL	3.36e-04	171	86	4	e9c42ce444d42cbb4f97e81393756531bfe61637
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POTEE CD7 POTEF ITGAL	3.43e-04	172	86	4	c74c1d47b133eb5d0f762a06e421252a76b4672b
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B USP53 KNTC1 NAT8	3.51e-04	173	86	4	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B USP53 KNTC1 NAT8	3.51e-04	173	86	4	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	ILEUM-inflamed-(1)_T_(gd)\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD7 ATP8A1 ACTB ACTG1	3.51e-04	173	86	4	85c3e227c81c6ab70148639381389fba3ac5e088
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK10 CD7 TCP11L2 TRAV38-2DV8	3.51e-04	173	86	4	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK10 CD7 ACTB ITGAL	3.58e-04	174	86	4	7ebf06076946729c1af25109df6066731097c3b1
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK10 CD7 ACTB ITGAL	3.58e-04	174	86	4	90961e8839514985712b8b986aec3391bb249ba7
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	STK10 CD7 TTC16 ITGAL	3.58e-04	174	86	4	33d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK10 CD7 ACTB ITGAL	3.58e-04	174	86	4	c4b0987d9394f977fe6bc6a4214a6d8d73d0abcc
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRY GRB10 ARHGEF17 RYR2	3.58e-04	174	86	4	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD7 ZDBF2 ITGAL PHLDB2	3.66e-04	175	86	4	06eace2e681980456299167b48bd49bcfea5e940
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B1\|343B / Donor, Lineage, Cell class and subclass (all cells)	STK10 CD7 ACTG1 ITGAL	3.66e-04	175	86	4	b1003230c39b2a9ceb43cb80728061d906ed0835
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-tDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD7 SCARA5 ACTB ACTG1	3.74e-04	176	86	4	fb07a047a3a7a8d03bfcc28eea3da2eaa0f6b733
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	CD7 TTC16 TRAV38-2DV8 TRAV38-1	3.74e-04	176	86	4	9399e174d14e81cc977fcb48facf844ee6726603
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZSWIM3 ELAPOR1 ZDBF2 SLC38A6	3.82e-04	177	86	4	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEAD2 ACTG1 ARHGEF17 RYR2	3.91e-04	178	86	4	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	droplet-Liver-LIVER-NPC-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8B MBL2 BDH1 MOCS2	3.99e-04	179	86	4	10baf575f06f9a15384bcdc751446b4670acf942
ToppCell	-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	PIEZO2 CD7 TRA RYR2	3.99e-04	179	86	4	e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-tDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TRBV29-1 CD7 SCARA5 TRAV38-2DV8	4.07e-04	180	86	4	3d9f3e6f13e558279b4ef43e2c44c7c50d761745
ToppCell	RSV-Healthy-0\|RSV / Virus stimulation, Condition and Cluster	NCOA6 ZSWIM3 ACTB PLIN3	4.07e-04	180	86	4	974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE NAT8B POTEF ACTB	4.07e-04	180	86	4	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STK10 CD7 TTC16 ITGAL	4.07e-04	180	86	4	bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE NAT8B POTEF ACTB	4.07e-04	180	86	4	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC7 DSCAM MBD6 TBC1D9	4.07e-04	180	86	4	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	ILEUM-non-inflamed-(1)_T_(gd)\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD7 ATP8A1 ACTB ACTG1	4.07e-04	180	86	4	44c37644973c4fc555dc966f8cfe1f4f81fef300
ToppCell	ICU-NoSEP-Myeloid-tDC\|ICU-NoSEP / Disease, Lineage and Cell Type	SCARA5 ZDBF2 SMOX TRAV38-2DV8	4.07e-04	180	86	4	be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC7 DSCAM MBD6 TBC1D9	4.07e-04	180	86	4	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	RSV-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	NCOA6 ZSWIM3 ACTB PLIN3	4.07e-04	180	86	4	703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STK10 CD7 TTC16 ITGAL	4.07e-04	180	86	4	c62417f205bcbf3b212ae177f63562ec6467c855
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STK10 CD7 ATP8A1 ITGAL	4.16e-04	181	86	4	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	PTPN13 PDE10A ARHGEF17 MEOX2	4.16e-04	181	86	4	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	PTPN13 PDE10A ARHGEF17 MEOX2	4.25e-04	182	86	4	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD7 ZSWIM3 TYW1B ING4	4.25e-04	182	86	4	69b5cae6fe3bbb0fc60bd2f71b6cfa6cbb0b00ee
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CD7 ACTB ACTG1 ITGAL	4.25e-04	182	86	4	c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell	wk_08-11-Hematologic-Myeloid-pre-pDC/DC5\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD7 IGHV1-69-2 ITGAL IGHV1-69D	4.25e-04	182	86	4	fec8a2d6d4099722b8e1bb41222108ed74268fcf
ToppCell	severe_influenza-gd_T\|severe_influenza / disease group, cell group and cell class (v2)	FNDC7 CD7 ATP8A1 TTC16	4.25e-04	182	86	4	b6b44c90af3f0c0dddb2b171087865d8c15a3973
Disease	Liver Cirrhosis, Experimental	FZD8 STK10 FRY CD7 NAT8 ITGAL BDH1 PLIN3 TBC1D9 CES2 MEOX2	3.50e-06	774	74	11	C0023893
Disease	Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation	ACTB ACTG1	6.20e-06	2	74	2	C1855722
Disease	Baraitser-Winter syndrome	ACTB ACTG1	6.20e-06	2	74	2	cv:C1853623
Disease	Fryns-Aftimos Syndrome	ACTB ACTG1	6.20e-06	2	74	2	C1853623
Disease	Uveoretinal Coloboma	ACTB ACTG1	1.29e-04	7	74	2	C4554007
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTB ACTG1	1.72e-04	8	74	2	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTB ACTG1	1.72e-04	8	74	2	DOID:0081112 (implicated_via_orthology)
Disease	Moyamoya disease (implicated_via_orthology)	ACTB ACTG1	1.72e-04	8	74	2	DOID:13099 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTB ACTG1	1.72e-04	8	74	2	DOID:14004 (implicated_via_orthology)
Disease	Congenital ocular coloboma (disorder)	ACTB ACTG1	2.21e-04	9	74	2	C0009363
Disease	Congenital neurologic anomalies	ACTB ACTG1	2.76e-04	10	74	2	C0497552
Disease	intestinal atresia (implicated_via_orthology)	ACTB ACTG1	2.76e-04	10	74	2	DOID:10486 (implicated_via_orthology)
Disease	Cranioschisis	ACTB ACTG1	2.76e-04	10	74	2	C0265541
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTB ACTG1	2.76e-04	10	74	2	DOID:13832 (implicated_via_orthology)
Disease	N-acetylphenylalanine measurement	NAT8 C2orf78	3.36e-04	11	74	2	EFO_0800019
Disease	N-acetyl-2-aminooctanoate measurement	NAT8B NAT8	4.03e-04	12	74	2	EFO_0800567
Disease	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	ARHGEF17 GLP2R	5.54e-04	14	74	2	EFO_0004307, EFO_0008464
Disease	triacylglycerol 48:4 measurement	DSCAM MBL2	5.54e-04	14	74	2	EFO_0010407
Disease	N-acetylarginine measurement	MBL2 NAT8	7.28e-04	16	74	2	EFO_0021429
Disease	Lymphatic Metastasis	ING4 TP53BP1	1.94e-03	26	74	2	C0024232

Protein segments in the cluster

Peptide	Gene	Start	Entry
DTETLCYVMPSSSAR	TDG	261	Q13569
SSMCVSSDLLSDIYK	ASH1L	811	Q9NR48
VYEDMSHSRCNTLSS	CD7	221	P09564
SAVDVSSSLTMSEYF	C2orf78	21	A6NCI8
SPCDLSNYTDLAMST	CPSF3	496	Q9UKF6
CTLTFSSFLYTVDSM	HTR3E	176	A5X5Y0
IAKMETYCSSGSTDT	BDH1	281	Q02338
LTSDSDSEVYCDSME	ACBD5	301	Q5T8D3
EMATAASSSSLEKSY	ACTB	226	P60709
EMATAASSSSLEKSY	ACTG1	226	P63261
AYCLMSSVSTSSEAI	FAM106A	71	Q4KMX7
SSEAIMSTELLANYC	FAM106A	81	Q4KMX7
SLSSSEPQAMCYIET	ATP8A1	171	Q9Y2Q0
YLALESMCTLASSEF	AP2A2	346	O94973
STDSSMEFSISTECL	KIAA1107	216	Q9UPP5
ISLMSLSSDGCIYET	NOL11	216	Q9H8H0
LMCIVYGSSLDTTSS	OOSP3	111	A0A2R8YFM6
SMSLYTAASVIDTAS	ARHGEF17	1331	Q96PE2
VDEIMTDTSTSYLLC	MSH3	356	P20585
EMATVASSSSLEKSY	POTEF	926	A5A3E0
AYCLMSSVSTSSEAI	FAM106C	71	P0CH98
SSEAIMSTELLANYC	FAM106C	81	P0CH98
ATLYRSMETTCSHSS	MBD6	111	Q96DN6
YTVMALSDSSELTCS	FNDC7	231	Q5VTL7
IASNTDECTATLMYA	ELAPOR1	166	Q6UXG2
MEYCSSGSLLSVLES	IKBKE	86	Q14164
LSCSDTSLYETLMYL	OR2T5	191	Q6IEZ7
LKLSCTDTSAYETAM	OR2T7	176	P0C7T2
DTCAYEMALSTSGVL	OR2Z1	191	Q8NG97
TMEKLSYHSICTSEE	PDE10A	431	Q9Y233
SFTRSTVAVYSTCML	PEX3	111	P56589
SDSMSEDCLYLSIYT	CES2	116	O00748
LLSMVAASYSETVTC	MBL2	11	P11226
DMDTSLILEYCSTFQ	KNTC1	1441	P50748
TTAYTDLSSLTSEDM	IGHV1-38-4	96	P0DTW3
MSYPELSTSSSSCII	MEOX2	36	P50222
ADTSTDTAYMELSSL	IGHV1-69-2	91	A0A0G2JMI3
ADESTSTAYMELSSL	IGHV1-69D	91	A0A0B4J2H0
LSCSDTSLYETLMYL	OR2T29	191	Q8NH02
DIYTSLCSSTMEDSE	NCOA6	11	Q14686
EMATAASSSSLEKSY	POTEE	926	Q6S8J3
TLCMDYNRTDLTTAA	FZD8	146	Q9H461
SYLSEMSTSCRSVQV	GLP2R	251	O95838
SVYASSSCSMDSLAS	DENND5B	146	Q6ZUT9
ASLESLYSACSMQSD	GRB10	61	Q13322
MATSTMSVCSSAYSD	KRTAP10-3	1	P60369
MSVCSSDLSYSSRVC	KRTAP10-4	1	P60372
FDQVISSMSSLSEYC	FRY	106	Q5TBA9
RMCASYSELELVTSA	DPEP3	166	Q9H4B8
MLEKLSDTYTCFSTE	HPS1	61	Q92902
MYLHTVSDCDTSSIC	SCARA5	6	Q6ZMJ2
SGMYLCCLSTSRSST	RYR2	126	Q92736
ATEYMSSARSLSSEE	ING4	46	Q9UNL4
SNLSLMDLCYSSVIT	OR8A1	81	Q8NGG7
SSMDLLCTADRDFSS	PTPN13	301	Q12923
MVSTESASSTYEELA	DSCAM	1801	O60469
LTSLYFQESTMTRCS	TRMT2B	276	Q96GJ1
SRFSESMASLSDYEC	TCP11L2	21	Q8N4U5
QLTCFSITCSSTMSY	KRT34	31	O76011
MSSLEISSSCFSLET	MOCS2	1	O96007
SSTCDMVSAAYASTK	PLIN3	36	O60664
LLSMCIQTAVTSYED	SLC38A6	96	Q8IZM9
IDTTLYTSSPSCMSL	SIPA1L3	1311	O60292
VSCETASDMYSLGTV	SCYL2	241	Q6P3W7
SQYESLEHMTLTCSS	TEAD2	331	Q15562
SMSKTCTYEGCSETT	RFXAP	136	O00287
LMTSTASEAASYEFT	DRG2	81	P55039
GEIEASSMFSLCSSL	ITGAL	1041	P20701
LDSSDSMETSISACS	PHLDB2	1006	Q86SQ0
FLSMLSSVDACYSSV	OR5T2	101	Q8NGG2
ETVSLTTYFSVDSCM	USP53	1031	Q70EK8
TTYFSVDSCMTDTYR	USP53	1036	Q70EK8
MSVQEAETVTLSCTY	TRA	31	P0DTU3
SVSSMSEFESLLDCS	SOGA1	926	O94964
DCSSLCTSESMDYGT	STK10	486	O94804
TKDDSSMSSYSVLSA	TBC1D9	1156	Q6ZT07
YMALTTCLDTSPSEE	PRRG2	11	O14669
YLKVESCESSSHSMD	SMOX	201	Q9NWM0
DSISSEPTQCTMLYS	PIEZO2	1746	Q9H5I5
IDMEVRSYDCSSSEL	ZDBF2	736	Q9HCK1
DSCKLMLSTSEYSQS	TP53BP1	511	Q12888
SNMSPEDSSIYLCSV	TRBV29-1	96	A0A5B7
ASTDVEMTSSAYRDT	NSD3	636	Q9BZ95
LACNTYMDSLDIVTS	ZSWIM3	386	Q96MP5
MSVQEAETVTLSCTY	TRAV38-2DV8	31	A0JD32
TEMSAICQEYRSTSA	TTC16	626	Q8NEE8
LSTEMTPCYISLSED	TRIM64C	291	A6NLI5
MNYSYSSLCLSSEES	WNK4	1111	Q96J92
VTYCRESSASSLTMA	TYW1B	541	Q6NUM6
MSVQEAETVTLSCTY	TRAV38-1	31	A0A0B4J264
RTDMSDITKSYLSEC	NAT8B	91	Q9UHF3
CTDMSDITKSYLSER	NAT8	91	Q9UHE5