Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine kinase activity

SMG1 MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4

1.25e-0636311512GO:0106310
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

SMG1 MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4

1.03e-0544611512GO:0004674
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

SMG1 MAP2K4 MARK3 STK17A SPEG NT5C3A TSSK2 HUNK SIK3 PIP4K2A MAPK1 MAPK3 TP53RK MAPK4 FYN

1.38e-0570911515GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

SMG1 MAP2K4 MARK3 STK17A SPEG NT5C3A TSSK2 FPGT HUNK SIK3 PIP4K2A POLI MAPK1 MAPK3 TP53RK MAPK4 FYN

2.61e-0593811517GO:0016772
GeneOntologyMolecularFunctionolfactory receptor activity

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

3.96e-0543111511GO:0004984
GeneOntologyMolecularFunctionprotein kinase activity

SMG1 MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4 FYN

4.23e-0560011513GO:0004672
GeneOntologyMolecularFunctionhydroxyacylglutathione hydrolase activity

HAGHL HAGH

9.83e-0531152GO:0004416
GeneOntologyMolecularFunctionMAP kinase activity

MAPK1 MAPK3 MAPK4

9.87e-05161153GO:0004707
GeneOntologyMolecularFunctionkinase activity

SMG1 MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 PIP4K2A MAPK1 MAPK3 TP53RK MAPK4 FYN

1.27e-0476411514GO:0016301
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK3 SIK3 FYN

2.65e-04221153GO:0050321
GeneOntologyMolecularFunctiondolichyl-diphosphooligosaccharide-protein glycotransferase activity

STT3A STT3B

3.25e-0451152GO:0004579
GeneOntologyMolecularFunctionoligosaccharyl transferase activity

STT3A STT3B

3.25e-0451152GO:0004576
GeneOntologyMolecularFunctionvolume-sensitive anion channel activity

LRRC8E LRRC8A

1.15e-0391152GO:0005225
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

3.02e-0543211511GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

5.88e-0546511511GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

8.56e-0548511511GO:0050907
GeneOntologyBiologicalProcesssensory perception

OR2A14 MYO7A OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 MAPK1 OR2Z1 MAPK3 FYN CNGA1 NIPBL OR4C5 OR2W6P

9.17e-05107211517GO:0007600
GeneOntologyBiologicalProcessco-translational protein modification

STT3A STT3B

9.21e-0531152GO:0043686
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 FYN OR4C5 OR2W6P

9.98e-0558211512GO:0050906
GeneOntologyCellularComponentlysosome

LRRC8E FUT10 MYO7A IST1 APOB BLOC1S1 SLC66A1 AP2A1 PIP4K2A LRRC8A ARRDC3 MAPK1 DNAJC3 HSP90AA1

1.48e-0481111514GO:0005764
GeneOntologyCellularComponentlytic vacuole

LRRC8E FUT10 MYO7A IST1 APOB BLOC1S1 SLC66A1 AP2A1 PIP4K2A LRRC8A ARRDC3 MAPK1 DNAJC3 HSP90AA1

1.48e-0481111514GO:0000323
DomainS_TKc

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4

1.05e-0535911211SM00220
DomainProtein_kinase_ATP_BS

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 MAPK4 FYN

1.75e-0537911211IPR017441
DomainPROTEIN_KINASE_ATP

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4 FYN

2.01e-0545911212PS00107
DomainKinase-like_dom

SMG1 MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4 FYN

2.21e-0554211213IPR011009
DomainMAPK_ERK1/2

MAPK1 MAPK3

3.56e-0521122IPR008349
DomainSTT3

STT3A STT3B

3.56e-0521122PF02516
DomainOligo_trans_STT3

STT3A STT3B

3.56e-0521122IPR003674
DomainProt_kinase_dom

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4 FYN

3.74e-0548911212IPR000719
DomainPROTEIN_KINASE_DOM

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 TP53RK MAPK4 FYN

4.04e-0549311212PS50011
DomainSer/Thr_kinase_AS

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 MAPK4

5.77e-0535711210IPR008271
DomainPROTEIN_KINASE_ST

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 MAPK4

6.48e-0536211210PS00108
DomainPkinase

MAP2K4 MARK3 STK17A SPEG TSSK2 HUNK SIK3 MAPK1 MAPK3 MAPK4

9.90e-0538111210PF00069
DomainOlfact_rcpt

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

1.28e-0439311210IPR000725
DomainLRRC8_Pannexin-like

LRRC8E LRRC8A

3.52e-0451122IPR021040
DomainPannexin_like

LRRC8E LRRC8A

3.52e-0451122PF12534
DomainCRAL-TRIO_dom

PLEKHG4 ATCAY MCF2

6.17e-04281123IPR001251
DomainCUT

CUX2 CUX1

7.34e-0471122PS51042
DomainCUT

CUX2 CUX1

7.34e-0471122PF02376
DomainCUT_dom

CUX2 CUX1

7.34e-0471122IPR003350
DomainCUT

CUX2 CUX1

7.34e-0471122SM01109
DomainCa/CaM-dep_Ca-dep_prot_Kinase

MARK3 STK17A TSSK2 HUNK

7.85e-04691124IPR020636
DomainMAP_kinase_CS

MAPK1 MAPK3

2.26e-03121122IPR003527
DomainCRAL_TRIO_2

ATCAY MCF2

2.26e-03121122PF13716
DomainCullin_repeat-like_dom

CUL2 EXOC8

2.26e-03121122IPR016159
DomainMAPK

MAPK1 MAPK3

2.26e-03121122PS01351
Domain7tm_1

OR2A14 MCHR1 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

2.49e-0367711211PF00001
DomainLactamase_B

HAGHL HAGH

2.66e-03131122PF00753
DomainG_PROTEIN_RECEP_F1_1

OR2A14 MCHR1 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

2.73e-0368511211PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2A14 MCHR1 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

2.91e-0369111211PS50262
DomainGPCR_Rhodpsn

OR2A14 MCHR1 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

2.95e-0369211211IPR000276
DomainLactamase_B

HAGHL HAGH

3.56e-03151122SM00849
PathwayPID_TELOMERASE_PATHWAY

XRCC5 TGFB1 MAPK1 MAPK3 HSP90AA1

8.25e-0567945M105
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA4 FYN HSP90AA1

9.91e-0514943MM15029
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA4 FYN HSP90AA1

1.51e-0416943M16498
PathwaySA_PTEN_PATHWAY

RBL2 MAPK1 MAPK3

1.82e-0417943M12771
PathwayBIOCARTA_MAPK_PATHWAY

MAP2K4 TGFB1 MAPK1 MAPK3 MAPK4

2.03e-0481945M13863
PathwayWP_IL11_SIGNALING

TGFB1 MAPK1 MAPK3 FYN

2.05e-0444944M39716
PathwayPID_ANTHRAX_PATHWAY

MAP2K4 MAPK1 MAPK3

2.18e-0418943M267
PathwayBIOCARTA_ECM_PATHWAY

MAPK1 MAPK3 FYN

2.57e-0419943M6355
PathwayREACTOME_SENSORY_PERCEPTION

OR2A14 MYO7A APOB OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 CNGA1 OR4C5

2.95e-046369413M41834
PathwayWP_IL3_SIGNALING

TGFB1 MAPK1 MAPK3 FYN

3.12e-0449944M39722
PathwayBIOCARTA_ECM_PATHWAY

MAPK1 MAPK3 FYN

3.50e-0421943MM1390
PathwayBIOCARTA_CERAMIDE_PATHWAY

MAP2K4 MAPK1 MAPK3

3.50e-0421943M19943
PathwayWP_GNAQ_PATHWAYS_IN_PORTWINE_STAIN

MAP2K4 MAPK1 MAPK3

3.50e-0421943M48342
PathwayREACTOME_NPAS4_REGULATES_EXPRESSION_OF_TARGET_GENES

MAGED1 MAPK1 MAPK3

4.03e-0422943M46437
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_USP8_TO_EGFR_ERK_ACTH_SIGNALING_PATHWAY

MAPK1 MAPK3

4.34e-045942M49028
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_BRAF_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

4.34e-045942M49016
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

4.34e-045942M49004
PathwayWP_TCA_CYCLE_NUTRIENT_USE_AND_INVASIVENESS_OF_OVARIAN_CANCER

MAPK1 MAPK3

4.34e-045942M39621
PathwayBIOCARTA_PELP1_PATHWAY

MAPK1 MAPK3

4.34e-045942MM1575
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5

4.54e-044179410M4072
PathwayBIOCARTA_CERAMIDE_PATHWAY

MAP2K4 MAPK1 MAPK3

4.62e-0423943MM1367
PathwayWP_CARDIAC_HYPERTROPHIC_RESPONSE

MAP2K4 TGFB1 MAPK1 MAPK3

4.87e-0455944M39685
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

MAP2K4 TGFB1 MAPK1 MAPK3 MAPK4

5.17e-0499945MM15905
PathwayWP_IL6_SIGNALING_PATHWAY

MAP2K4 MAPK1 MAPK3 FYN HSP90AA1

5.41e-04100945MM15826
PathwayPID_LYMPH_ANGIOGENESIS_PATHWAY

MAP2K4 MAPK1 MAPK3

5.94e-0425943M274
PathwayWP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION

MAPK1 MAPK3 MAPK4

5.94e-0425943M39384
PathwayREACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS

LRRC8E SLC66A1 LRRC8A

5.94e-0425943MM15172
PathwayWP_IL7_SIGNALING

MAPK1 MAPK3 FYN

5.94e-0425943M39499
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

MAP2K4 TGFB1 MAPK1 MAPK3 MAPK4

6.47e-04104945M39625
PathwayBIOCARTA_SAM68_PATHWAY

MAPK1 MAPK3

6.48e-046942M22052
PathwayBIOCARTA_PELP1_PATHWAY

MAPK1 MAPK3

6.48e-046942M22062
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

MAPK1 MAPK3

6.48e-046942M27559
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

MAPK1 MAPK3

6.48e-046942MM15273
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY

MAPK1 MAPK3

6.48e-046942M47766
PathwayBIOCARTA_SAM68_PATHWAY

MAPK1 MAPK3

6.48e-046942MM1567
PathwayREACTOME_SCAVENGING_BY_CLASS_F_RECEPTORS

APOB HSP90AA1

6.48e-046942M27222
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

MAPK1 MAPK3

6.48e-046942M47936
PathwayREACTOME_SIGNALING_BY_NODAL

MAPK1 MAPK3

6.48e-046942MM14517
PathwayBIOCARTA_AT1R_PATHWAY

MAP2K4 MAPK1 MAPK3

6.68e-0426943MM1346
PathwayPID_VEGFR1_PATHWAY

MAPK1 MAPK3 HSP90AA1

6.68e-0426943M226
PathwayREACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS

LRRC8E SLC66A1 LRRC8A

6.68e-0426943M27424
PathwayKEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY

MAP2K4 MAPK1 MAPK3

6.68e-0426943M47565
PathwayBIOCARTA_PYK2_PATHWAY

MAP2K4 MAPK1 MAPK3

6.68e-0426943MM1431
PathwayPID_ALK1_PATHWAY

TGFB1 MAPK1 MAPK3

6.68e-0426943M185
PathwayPID_FCER1_PATHWAY

MAP2K4 MAPK1 MAPK3 FYN

6.80e-0460944M7
PathwayBIOCARTA_AT1R_PATHWAY

MAP2K4 MAPK1 MAPK3

7.48e-0427943M14899
PathwayBIOCARTA_PYK2_PATHWAY

MAP2K4 MAPK1 MAPK3

7.48e-0427943M7739
PathwayWP_MAPK_CASCADE

MAP2K4 MAPK1 MAPK3

8.34e-0428943MM15976
PathwayWP_IL19_SIGNALING

TGFB1 MAPK1 MAPK3

8.34e-0428943M48111
PathwayPID_TRAIL_PATHWAY

MAP2K4 MAPK1 MAPK3

8.34e-0428943M79
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

MAPK1 MAPK3

9.04e-047942MM17070
PathwayREACTOME_SIGNALING_BY_LTK_IN_CANCER

MAPK1 MAPK3

9.04e-047942M48255
PathwayREACTOME_RSK_ACTIVATION

MAPK1 MAPK3

9.04e-047942M27369
PathwayREACTOME_SUPPRESSION_OF_APOPTOSIS

MAPK1 MAPK3

9.04e-047942M29815
PathwayBIOCARTA_BIOPEPTIDES_PATHWAY

MAPK1 MAPK3 FYN

9.25e-0429943MM1356
PathwayREACTOME_METALLOPROTEASE_DUBS

MYSM1 H2AC18 H2AC20

9.25e-0429943MM15291
PathwayBIOCARTA_BIOPEPTIDES_PATHWAY

MAPK1 MAPK3 FYN

9.25e-0429943M13494
PathwayKEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY

MAPK1 MAPK3 FYN

9.25e-0429943M47764
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

ARPC2 MAPK1 MAPK3 FYN HSP90AA1

9.81e-04114945MM14814
PathwayREACTOME_M_PHASE

CENPE IST1 PSME1 H2AC18 H2AC20 MAPK1 MAPK3 NIPBL HSP90AA1

1.10e-03387949MM15364
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1

1.14e-03389949M14091
PathwayPID_VEGFR1_2_PATHWAY

MAPK1 MAPK3 FYN HSP90AA1

1.15e-0369944M237
PathwayREACTOME_CELLULAR_SENESCENCE

MAP2K4 H2AC18 H2AC20 MAPK1 MAPK3

1.19e-03119945MM14901
PathwayBIOCARTA_STAT3_PATHWAY

MAPK1 MAPK3

1.20e-038942M22063
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

MAPK1 MAPK3

1.20e-038942M48010
PathwayBIOCARTA_STAT3_PATHWAY

MAPK1 MAPK3

1.20e-038942MM1576
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.20e-038942M47642
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.20e-038942M47643
PathwayKEGG_RENAL_CELL_CARCINOMA

CUL2 TGFB1 MAPK1 MAPK3

1.21e-0370944M13266
PathwayPID_CDC42_PATHWAY

MAP2K4 ARPC2 MAPK1 MAPK3

1.21e-0370944M81
PathwayPID_ALPHA_SYNUCLEIN_PATHWAY

MAPK1 MAPK3 FYN

1.24e-0332943M275
PathwayWP_PRION_DISEASE_PATHWAY

MAPK1 MAPK3 FYN

1.24e-0332943M39636
PathwayPID_NETRIN_PATHWAY

MAPK1 MAPK3 FYN

1.24e-0332943M108
PathwayREACTOME_CELL_CYCLE_MITOTIC

CENPE RBL2 IST1 PSME1 ORC5 H2AC18 H2AC20 MAPK1 MAPK3 NIPBL HSP90AA1

1.25e-035619411M5336
PathwayREACTOME_BACTERIAL_INFECTION_PATHWAYS

MAP2K4 MAPK1 MAPK3 HSP90AA1

1.28e-0371944M48033
PathwayPID_SYNDECAN_2_PATHWAY

TGFB1 MAPK1 MAPK3

1.36e-0333943M240
PathwayWP_MAPK_CASCADE

MAP2K4 MAPK1 MAPK3

1.36e-0333943M39594
PathwayBIOCARTA_INTEGRIN_PATHWAY

MAPK1 MAPK3 FYN

1.36e-0333943MM1426
PathwayBIOCARTA_INTEGRIN_PATHWAY

MAPK1 MAPK3 FYN

1.48e-0334943M3342
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

ARPC2 MAPK1 MAPK3

1.48e-0334943MM15265
PathwaySIG_CD40PATHWAYMAP

MAP2K4 MAPK1 MAPK3

1.48e-0334943M12705
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

MAGED1 MAPK1 MAPK3

1.48e-0334943M46422
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

MAP2K4 H2AC18 H2AC20 MAPK1 MAPK3

1.48e-03125945M27186
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA4 FYN

1.54e-039942MM15030
PathwayKEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.54e-039942M47641
PathwayREACTOME_SIGNALING_BY_NTRKS

AP2A1 MAPK1 MAPK3 FYN

1.57e-0375944MM14652
PathwayWP_2Q112_COPY_NUMBER_VARIATION_SYNDROME

CNNM3 MAPK1 MAPK3

1.61e-0335943M45521
PathwayKEGG_PRION_DISEASES

MAPK1 MAPK3 FYN

1.61e-0335943M13036
PathwayBIOCARTA_MAPK_PATHWAY

MAP2K4 TGFB1 MAPK1 MAPK3

1.65e-0376944MM1433
PathwayREACTOME_SENSORY_PERCEPTION

MYO7A APOB OR2J2 OR2F1 OR2AT4 CNGA1

1.69e-03190946MM15687
PathwayPID_PDGFRB_PATHWAY

MAP2K4 ARPC2 MAPK1 MAPK3 FYN

1.70e-03129945M186
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

ARPC2 MAPK1 MAPK3

1.75e-0336943M27549
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAP2K4 MAPK1 MAPK3

1.75e-0336943M39908
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

ARPC2 AP2A1 PLXNA4 MAPK1 MAPK3 FYN HSP90AA1

1.79e-03261947MM15676
PathwayREACTOME_M_PHASE

CENPE IST1 PSME1 H2AC18 H2AC20 MAPK1 MAPK3 NIPBL HSP90AA1

1.84e-03417949M27662
PathwayREACTOME_METALLOPROTEASE_DUBS

MYSM1 H2AC18 H2AC20

1.89e-0337943M27580
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

MAP2K4 MAPK1 MAPK3

1.89e-0337943MM14899
PathwayWP_NEOVASCULARIZATION_PROCESSES

TGFB1 MAPK1 MAPK3

1.89e-0337943M39506
PathwayKEGG_FC_EPSILON_RI_SIGNALING_PATHWAY

MAP2K4 MAPK1 MAPK3 FYN

1.90e-0379944M11816
PathwayREACTOME_SIGNAL_ATTENUATION

MAPK1 MAPK3

1.91e-0310942M14236
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

1.91e-083401151111875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

1.91e-083401151111802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

2.09e-083431151132295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

2.28e-083461151114611657
Pubmed

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.

DNAAF11 DNALI1 DNAH17 HSP90AA1

2.35e-0810115429916806
Pubmed

TGF-β-mediated sustained ERK1/2 activity promotes the inhibition of intracellular growth of Mycobacterium avium in epithelioid cells surrogates.

TGFB1 MAPK1 MAPK3

3.52e-083115321731758
Pubmed

Heterogeneous expression of four MAP kinase isoforms in human tissues.

MAPK1 MAPK3 MAPK4

3.52e-08311531319925
Pubmed

Paracrine TGF-β1 from breast cancer contributes to chemoresistance in cancer associated fibroblasts via upregulation of the p44/42 MAPK signaling pathway.

TGFB1 MAPK1 MAPK3

3.52e-083115333607074
Pubmed

Differential activation of MAPK signaling pathways by TGF-beta1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis.

TGFB1 MAPK1 MAPK3

3.52e-083115315068691
Pubmed

Genomic loci of human mitogen-activated protein kinases.

MAPK1 MAPK3 MAPK4

3.52e-08311538290275
Pubmed

Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2.

TGFB1 MAPK1 MAPK3

3.52e-083115326096876
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 CUX2 PCDHGA5 APOB XRCC5 SLC4A3 STT3B ARPC2 H2AC18 H2AC20 C6orf118 AP2A1 PIP4K2A STRN4 PLXNA4 IFT122 DNAJC3 NIPBL CUX1 HSP90AA1

5.37e-0814421152035575683
Pubmed

Non-redundant role of Shc in Erk activation by cytoskeletal reorganization.

STT3A MAPK1 MAPK3

1.41e-074115314576154
Pubmed

Biological and prognostic relevance of mitogen-activated protein kinases in pancreatic adenocarcinoma.

MAP2K4 MAPK1 MAPK3

1.41e-074115322158075
Pubmed

Cell type-dependent control of NF-Y activity by TGF-beta.

TGFB1 MAPK1 MAPK3

1.41e-074115316434965
Pubmed

A mechanism in Epstein-Barr virus oncogenesis: inhibition of transforming growth factor-beta 1-mediated induction of MAPK/p21 by LMP1.

TGFB1 MAPK1 MAPK3

1.41e-074115312441075
Pubmed

Sphingosine kinases and sphingosine-1-phosphate are critical for transforming growth factor beta-induced extracellular signal-regulated kinase 1 and 2 activation and promotion of migration and invasion of esophageal cancer cells.

TGFB1 MAPK1 MAPK3

1.41e-074115318426913
Pubmed

Transforming growth factorbeta(1) transactivates EGFR via an H(2)O(2)-dependent mechanism in squamous carcinoma cell line.

TGFB1 MAPK1 MAPK3

1.41e-074115319751964
Pubmed

Breast cancer-derived factors stimulate osteoclastogenesis through the Ca2+/protein kinase C and transforming growth factor-beta/MAPK signaling pathways.

TGFB1 MAPK1 MAPK3

3.50e-075115319801662
Pubmed

Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 Axis.

TGFB1 MAPK1 MAPK3

3.50e-075115326565025
Pubmed

Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.

TGFB1 MAPK1 MAPK3

3.50e-075115315247230
Pubmed

Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose.

TGFB1 MAPK1 MAPK3

3.50e-075115318456735
Pubmed

A G protein-coupled receptor and the intracellular synthase of its agonist functionally cooperate.

MAPK1 MAPK3 HSP90AA1

3.50e-075115324493589
Pubmed

Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.

TGFB1 MAPK1 MAPK3

3.50e-075115312130649
Pubmed

Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways.

MAP2K4 MAPK1 MAPK3

3.50e-075115312456688
Pubmed

VEGF induces proliferation, migration, and TGF-beta1 expression in mouse glomerular endothelial cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase.

TGFB1 MAPK1 MAPK3

3.50e-075115316039615
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

GRWD1 XRCC5 HSP90AA5P CNNM3 H2AC20 STRN4 HAGH MAPK1 MAPK3 DNAJC3 CUX1 HSP90AA1

4.72e-075731151228330616
Pubmed

Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development.

TGFB1 MAPK1 MAPK3

6.99e-076115328825193
Pubmed

Phosphatidylinositol 3-kinase/Akt pathway targets acetylation of Smad3 through Smad3/CREB-binding protein interaction: contribution to transforming growth factor beta1-induced Epstein-Barr virus reactivation.

TGFB1 MAPK1 MAPK3

6.99e-076115319589780
Pubmed

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice.

TGFB1 MAPK1 MAPK3

6.99e-076115321493862
Pubmed

TGF-beta1 induces COX-2 expression and PGE2 synthesis through MAPK and PI3K pathways in human mesangial cells.

TGFB1 MAPK1 MAPK3

6.99e-076115316820791
Pubmed

ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzeta-controlled ERK1/2 activity within the nucleus.

MAPK1 MAPK3 FYN

6.99e-076115316723512
Pubmed

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways.

TGFB1 MAPK1 MAPK3

6.99e-076115321713404
Pubmed

Divergence of epidermal growth factor - transforming growth factor beta signaling in embryonic orofacial tissue.

TGFB1 MAPK1 MAPK3

6.99e-076115312880367
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CUL2 FUT10 MARK3 SIK3 STT3A STT3B NSD3 AP2A1 DNAH17 MAPK1 MAPK3 MAPK4 FYN

9.47e-077301151334857952
Pubmed

The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells.

TGFB1 MAPK1 MAPK3

1.22e-067115337795611
Pubmed

Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma.

TGFB1 MAPK1 MAPK3

1.22e-067115321292498
Pubmed

Lipopolysaccharide inhibits transforming growth factor-beta1-stimulated Smad6 expression by inducing phosphorylation of the linker region of Smad3 through a TLR4-IRAK1-ERK1/2 pathway.

TGFB1 MAPK1 MAPK3

1.22e-067115321295571
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CUL2 POGLUT3 PIGK APOB PSME1 XRCC5 STT3A STT3B NSD3 TGFB1 IVNS1ABP AP2A1 HAGH FYN DNAJC3 NIPBL HSP90AA1

1.30e-0612971151733545068
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

CUL2 MAGED1 HAGHL RBL2 CNNM3 PIP4K2A STRN4 MAPK1 TP53RK HSP90AA1

1.84e-064321151023455922
Pubmed

The human olfactory receptor gene family.

OR2A14 OR2J2 OR2F1 OR10Z1 OR2K2 OR10AG1 OR4C15 OR2AT4 OR2Z1 OR4C5 OR2W6P

1.93e-065411151114983052
Pubmed

Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development.

TGFB1 MAPK1 MAPK3

1.95e-068115319161227
Pubmed

Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.

MAPK1 MAPK3 FYN

2.92e-069115314530346
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

MARK3 SIK3 MAPK1 MAPK3

3.33e-0631115431636950
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAP2K4 MAGED1 CENPE SIK3 XRCC5 ARPC2 AP2A1 STRN4 DOCK7 MAPK1 MAPK3 NIPBL CUX1 HSP90AA1

3.78e-069631151428671696
Pubmed

IRX3/5 regulate mitotic chromatid segregation and limb bud shape.

CUX2 NIPBL CUX1

4.16e-0610115332907847
Pubmed

TGFβ pathway is required for viable gestation of Fanconi anemia embryos.

TGFB1 MAPK1 MAPK3

4.16e-0610115336441774
Pubmed

The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice.

MAPK1 MAPK3 CUX1

5.70e-0611115327504805
Pubmed

Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain.

MAPK1 MAPK3 CUX1

5.70e-0611115327680501
Pubmed

JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

MAPK1 MAPK3 FYN

5.70e-0611115318499741
Pubmed

MAP4K4 is involved in the neuronal development of retinal photoreceptors.

MAPK1 MAPK3 MAPK4

7.58e-0612115337290629
Pubmed

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice.

DNALI1 MAPK1 MAPK3

7.58e-0612115329317443
Pubmed

The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway.

MAPK1 MAPK3 CUX1

9.83e-0613115325698753
Pubmed

A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.

TGFB1 MAPK1 MAPK3

9.83e-0613115318483625
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

SMG1 MAP2K4 HAGHL MARK3 RBL2 STK17A SIK3 STT3B AP2A1 PIP4K2A MAPK1 MAPK3 FYN

1.03e-059101151336736316
Pubmed

Expression and activation of mitogen-activated protein kinase in the human endometrium during the menstrual cycle.

MAPK1 MAPK3

1.08e-052115216796978
Pubmed

Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein.

MAPK1 MAPK3

1.08e-05211529792705
Pubmed

Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2.

MAPK1 MAPK3

1.08e-052115227564099
Pubmed

A role for ERK2 in reconsolidation of fear memories in mice.

MAPK1 MAPK3

1.08e-052115216504549
Pubmed

Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.

CUX2 CUX1

1.08e-052115225059644
Pubmed

MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network.

MAPK1 MAPK3

1.08e-052115237999644
Pubmed

Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.

MAPK1 MAPK3

1.08e-052115218070930
Pubmed

Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells.

MAPK1 MAPK3

1.08e-052115218224451
Pubmed

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.

MAPK1 MAPK3

1.08e-052115223993963
Pubmed

Mechanical stress promotes angiogenesis through fibroblast exosomes.

MAPK1 MAPK3

1.08e-052115232962863
Pubmed

Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells.

MAPK1 MAPK3

1.08e-052115219801509
Pubmed

The ERK phosphorylation levels in the amygdala predict anxiety symptoms in humans and MEK/ERK inhibition dissociates innate and learned defensive behaviors in rats.

MAPK1 MAPK3

1.08e-052115234316004
Pubmed

Inhibition of the ERK pathway prevents HIVgp120-induced REM sleep increase.

MAPK1 MAPK3

1.08e-052115211532249
Pubmed

Fyn is a downstream target of the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta-signaling pathway: regulation of tyrosine phosphorylation of Fyn by pleiotrophin.

PTPRZ1 FYN

1.08e-052115215925565
Pubmed

Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.

MAPK1 MAPK3

1.08e-052115228295277
Pubmed

ERK1/2 controls Na,K-ATPase activity and transepithelial sodium transport in the principal cell of the cortical collecting duct of the mouse kidney.

MAPK1 MAPK3

1.08e-052115215456767
Pubmed

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.

MAPK1 MAPK3

1.08e-052115212810726
Pubmed

Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent.

MAPK1 MAPK3

1.08e-052115212218045
Pubmed

Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2.

MAPK1 MAPK3

1.08e-052115229789577
Pubmed

Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation.

MAPK1 MAPK3

1.08e-052115227528403
Pubmed

Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder.

MAPK1 MAPK3

1.08e-052115221705143
Pubmed

ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis.

MAPK1 MAPK3

1.08e-052115216081808
Pubmed

Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factor.

MAPK1 MAPK3

1.08e-052115215143154
Pubmed

Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK.

MAPK1 MAPK3

1.08e-052115212555071
Pubmed

ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer.

MAPK1 MAPK3

1.08e-052115225085753
Pubmed

ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation.

MAPK1 MAPK3

1.08e-052115220840867
Pubmed

ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.

MAPK1 MAPK3

1.08e-052115219286961
Pubmed

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.

MAPK1 MAPK3

1.08e-052115219147767
Pubmed

Anaplasma phagocytophilum AptA modulates Erk1/2 signalling.

MAPK1 MAPK3

1.08e-052115220716207
Pubmed

Leukaemia inhibitory factor mediated proliferation of HTR-8/SVneo trophoblast cells is dependent on activation of extracellular signal-regulated kinase 1/2.

MAPK1 MAPK3

1.08e-052115221635820
Pubmed

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo.

MAPK1 MAPK3

1.08e-052115217709754
Pubmed

Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways.

MAPK1 MAPK3

1.08e-052115223643895
Pubmed

A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.

MAPK1 MAPK3

1.08e-052115228986121
Pubmed

Calcitonin targets extracellular signal-regulated kinase signaling pathway in human cancers.

MAPK1 MAPK3

1.08e-052115218055485
Pubmed

Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer.

MAPK1 MAPK3

1.08e-052115232444778
Pubmed

Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.

MAPK1 MAPK3

1.08e-052115215322023
Pubmed

MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.

MAPK1 MAPK3

1.08e-052115215096454
Pubmed

Both ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication.

MAPK1 MAPK3

1.08e-052115225803100
Pubmed

Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation.

MAPK1 MAPK3

1.08e-052115220404333
Pubmed

Desialylation of glycoconjugates on the surface of monocytes activates the extracellular signal-related kinases ERK 1/2 and results in enhanced production of specific cytokines.

MAPK1 MAPK3

1.08e-052115214634064
Pubmed

Deletion of ERK1 and ERK2 in the CNS causes cortical abnormalities and neonatal lethality: Erk1 deficiency enhances the impairment of neurogenesis in Erk2-deficient mice.

MAPK1 MAPK3

1.08e-052115221248139
Pubmed

FasL expression in cardiomyocytes activates the ERK1/2 pathway, leading to dilated cardiomyopathy and advanced heart failure.

MAPK1 MAPK3

1.08e-052115226566650
Pubmed

[Effect of ERK1/2 signal pathway on the proliferation of lung fibroblast activated by SiO₂].

MAPK1 MAPK3

1.08e-052115221126445
Pubmed

Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.

MAPK1 MAPK3

1.08e-052115217297454
Pubmed

Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways.

MAPK1 MAPK3

1.08e-052115215542825
InteractionRPS6KA4 interactions

HSP90AA5P H2AC18 H2AC20 MAPK1 MAPK3 MAPK4 HSP90AA1

9.77e-071001067int:RPS6KA4
GeneFamilyOlfactory receptors, family 2

OR2A14 OR2J2 OR2F1 OR2K2 OR2AT4 OR2Z1 OR2W6P

1.10e-06113867149
GeneFamilySTT3 oligosaccharyltransferase catalytic subunits|Oligosaccharyltransferase complex subunits

STT3A STT3B

2.24e-052862444
GeneFamilyMitogen-activated protein kinases

MAPK1 MAPK3 MAPK4

2.87e-0513863651
GeneFamilyVolume regulated anion channel subunits

LRRC8E LRRC8A

2.22e-0458621158
GeneFamilyCUT class homeoboxes and pseudogenes

CUX2 CUX1

7.88e-049862527
GeneFamilyOligosaccharyltransferase complex subunits

STT3A STT3B

1.43e-0312862445
GeneFamilyDyneins, axonemal

DNALI1 DNAH17

2.90e-0317862536
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HAGHL DNALI1 EFHC1 C6orf118 PTPRZ1 ALDH3A1 TMC5 ALOX12B

5.22e-08200115896701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

MYO7A HAGHL DNAAF11 EFHC1 C6orf118 IFT122 TMC5

8.43e-0719811576d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HAGHL DNAAF11 EFHC1 C6orf118 ALDH3A1 TMC5 ALOX12B

8.72e-07199115715f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGSL1 DNALI1 EFHC1 C6orf118 ALDH3A1 TMC5

7.40e-061801156adf5db5bfa9a38b1227ab0beccd8d6f3eea67ac0
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A TGFB1 OR2AT4 PIP4K2A MAPK1 FYN

7.40e-061801156512c005567ad9c78cc5cc83862fc1219bcf49f60
ToppCellmulticiliated|World / shred by cell class for turbinate

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.07e-0519211560f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

STK17A SIK3 TGFB1 PIP4K2A MAPK1 FYN

1.13e-0519411565c58a2d1dd3c8ff77ce44d473239685e6b020909
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.17e-05195115660067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

CUX2 ATCAY HUNK PLXNA4 CUX1 HSP90AA1

1.20e-0519611569401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

STK17A PSME1 ARPC2 C5orf34 PIP4K2A FYN

1.20e-05196115617f17edadafdad9f24e88d708d7e1c765503131c
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

NT5C3A NSD3 FYN DNAJC3 NIPBL HSP90AA1

1.31e-05199115618a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HUNK OR2K2 PTPRZ1 RGS17 TMC5 SDK1

1.35e-052001156b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNALI1 C6orf118 PTPRZ1 ALDH3A1 TMC5 ALOX12B

1.35e-052001156cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNALI1 C6orf118 PTPRZ1 ALDH3A1 TMC5 ALOX12B

1.35e-052001156a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

DNAAF11 DNALI1 EFHC1 C6orf118 ALDH3A1 TMC5

1.35e-0520011563305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

APOB SLC4A3 PTPRZ1 ALDH3A1 CNGA1

5.47e-051571155dd08dc19d434e94a194076c462ee273c682abf55
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

APOB SLC4A3 PTPRZ1 ALDH3A1 CNGA1

5.47e-05157115570fd6c46db4250c7de5c4686a9500689402737f6
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HUNK PTPRZ1 RGS17 TMC5 SDK1

6.16e-0516111552d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUPT3H STK17A PIP4K2A MAPK1 FYN

7.12e-05166115562523e635784512b3261b672beaa7747cb9d114a
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAAF11 DNALI1 EFHC1 ALDH3A1 TMC5

7.33e-05167115526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUPT3H HAGHL STK17A TGFB1 H2AC18

7.53e-051681155235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUPT3H RGSL1 STK17A PIP4K2A FYN

7.53e-051681155b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A H2AC18 PIP4K2A MAPK1 FYN

8.19e-051711155f16cb64b8844c2668922c786888efaa9f873afcc
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A TGFB1 PIP4K2A MAPK1 FYN

9.63e-051771155fcdd71e2a727ae24b726a39216ea02c06df1f593
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARPC2 H2AC18 SF3A3 MAPK1 FYN

1.10e-041821155c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A TGFB1 PIP4K2A MAPK1 FYN

1.10e-041821155feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

STK17A ZBTB14 PIP4K2A MAPK1 FYN

1.10e-0418211559d727ab84da8de33f1021b492c90d8b4c2a8ea23
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

HUNK PTPRZ1 RGS17 TMC5 SDK1

1.10e-0418211553f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

HUNK PTPRZ1 RGS17 TMC5 SDK1

1.13e-041831155940cbe298e9c53b5622af09264586ed823d3141f
ToppCell356C-Lymphocytic-ILC-ILC-1|ILC / Donor, Lineage, Cell class and subclass (all cells)

STK17A ARPC2 TGFB1

1.19e-043711535208860d6b87c6c6fbf6e6c262fb2efc712ec2d3
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

HUNK GTF2IRD1 SDK1 CUX1 ACSS3

1.22e-041861155de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

MYO7A RBL2 STRN4 TP53RK KIF13A

1.22e-041861155f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HUNK GTF2IRD1 SDK1 CUX1 ACSS3

1.22e-0418611550b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

GTF2IRD1 SLC4A3 PGM5 ADPRHL1 MAPK4

1.28e-0418811556d249fe92d51a19da19ec14bb2262d394255d577
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118

1.28e-04188115582c006f43c93f4a867953a446864f02b44536a23
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118

1.28e-041881155da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118

1.31e-04189115557ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118

1.31e-041891155ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HUNK GTF2IRD1 DOCK7 CNGA1 SDK1

1.31e-0418911558ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-gdT|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUPT3H HAGHL STK17A PIP4K2A FYN

1.34e-041901155116314a27064d3005d950c9a9163b79ea438707b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HUNK GTF2IRD1 DOCK7 CNGA1 SDK1

1.34e-0419011554836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNALI1 EFHC1 C6orf118 ALDH3A1 HSP90AA1

1.38e-0419111553e84c453e8a151c42808fe2935f1d732e180008c
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

GTF2IRD1 SLC4A3 PGM5 ADPRHL1 MAPK4

1.38e-0419111555d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellNS-moderate-d_16-33-Lymphoid-Treg|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RBL2 STK17A TGFB1 PIP4K2A FYN

1.41e-04192115548d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SUPT3H NIPBL SDK1 HSP90AA1 ACSS3

1.41e-041921155916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellmoderate-Lymphoid-Treg|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RBL2 STK17A TGFB1 PIP4K2A FYN

1.41e-041921155e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.44e-041931155e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

SUPT3H NIPBL SDK1 HSP90AA1 ACSS3

1.44e-041931155e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 GTF2IRD1 PIP4K2A NIPBL CUX1

1.48e-041941155f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellILEUM-inflamed-(1)_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SUPT3H RBL2 PIP4K2A FYN HSP90AA1

1.48e-041941155cf22bd6afe51c42cb151c37a8b65c98649dae1a4
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 GTF2IRD1 PIP4K2A NIPBL CUX1

1.48e-041941155cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 GTF2IRD1 PIP4K2A NIPBL CUX1

1.48e-04194115566c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellmyeloid-CD16+_Monocyte|myeloid / Lineage and Cell class

SLC7A7 ARPC2 AP2A1 HAGH CUX1

1.48e-041941155aeeadfeb01827dbc7de6576c76fb2e41a3c59247
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|Liver / Manually curated celltypes from each tissue

STK17A SIK3 TGFB1 PIP4K2A FYN

1.52e-041951155972b09697b7b66fb8a27dfc0c0b05a844121f055
ToppCellT/NK_cells-CD8+_Naive_T_cell|World / Lineage and Cell class

STK17A ARPC2 TGFB1 PIP4K2A FYN

1.52e-04195115543f11068beea076e9caeb1572215c3f65c9308e1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.52e-041951155d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.52e-0419511550e763f36786515698b593e5c93f6a56619c1242d
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo|Liver / Manually curated celltypes from each tissue

STK17A SIK3 TGFB1 PIP4K2A FYN

1.52e-041951155c29c4ae95a756e3ced0f0747bbfe343590e5b8ab
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.52e-041951155581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.52e-04195115593b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HAGHL DNALI1 EFHC1 C6orf118 TMC5

1.52e-04195115579dc031258579ea328181dda33710dd897f1064a
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNALI1 EFHC1 C6orf118 ALDH3A1 TMC5

1.52e-04195115534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell(0)_NK_cells-(0)_NK_CD160pos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SUPT3H HAGHL STK17A FYN HSP90AA1

1.52e-0419511556cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.52e-0419511559651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RBL2 STK17A PIP4K2A FYN HSP90AA1

1.55e-041961155ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.55e-0419611551386003f5d885f0ea080934f7e05fe05f142a3d5
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SUPT3H STK17A PIP4K2A MAPK1 FYN

1.55e-0419611558a3a63129adfbe58558af91336f81d397c291ed0
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HAGHL DNAAF11 DNALI1 EFHC1 C6orf118

1.55e-041961155d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IST1 STT3A STT3B IVNS1ABP MAPK1

1.55e-041961155151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HUNK PTPRZ1 RGS17 TMC5 SDK1

1.55e-041961155c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellNS-critical-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNALI1 EFHC1 ALDH3A1 TMC5 HSP90AA1

1.59e-04197115532484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCellNS-critical-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNALI1 EFHC1 ALDH3A1 TMC5 HSP90AA1

1.59e-041971155009dc732c43bfdc0d5a662b2c7d1a7a86b0d1d24
ToppCellcritical-Epithelial-Ciliated-diff|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNALI1 EFHC1 ALDH3A1 TMC5 HSP90AA1

1.59e-04197115534fa5568eb5e5f1ee5d4c7e5d237997eaca573ae
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.59e-041971155d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

STK17A HUNK PTPRZ1 PLXNA4 FYN

1.63e-0419811556d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

STK17A HUNK PTPRZ1 PLXNA4 FYN

1.63e-0419811557943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HUNK PTPRZ1 RGS17 ALDH3A1 SDK1

1.63e-041981155af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

NT5C3A HUNK CNOT8 PTPRZ1 PLXNA4

1.63e-04198115590ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HUNK OR2K2 PTPRZ1 RGS17 TMC5

1.63e-041981155fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellLPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_only / Treatment groups by lineage, cell group, cell type

STK17A ARPC2 TGFB1 PIP4K2A FYN

1.67e-041991155b62a756b5472972156d05051a58671a58bef1f16
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|lymphoid / Lineage, cell class and subclass

HAGHL STK17A PSME1 ARPC2 PIP4K2A

1.67e-04199115522926327c93ede9f3408c99a0d56e373a33240ef
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|T_cell / Lineage, cell class and subclass

HAGHL STK17A PSME1 ARPC2 PIP4K2A

1.67e-0419911559ee40563e840a7fe97e7592539d42e19db438c64
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.71e-0420011556a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.71e-0420011558dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

STK17A PSME1 ARPC2 TGFB1 FYN

1.71e-04200115563077e1f801f1c08bd339f5517f5781da240c04f
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNALI1 EFHC1 C6orf118 PTPRZ1 TMC5

1.71e-042001155da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellSepsis-URO-Lymphocyte-T/NK-CD8+_Tem|URO / Disease, condition lineage and cell class

SUPT3H RBL2 STK17A PIP4K2A FYN

1.71e-042001155e621b46084839700e6dd338fdafc682a07cd698d
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNALI1 C6orf118 ALDH3A1 TMC5 ALOX12B

1.71e-0420011554992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellremission-CD8+_Tem|remission / disease stage, cell group and cell class

PSME1 ARPC2 TGFB1 FYN HSP90AA1

1.71e-042001155f1e4b8fcb422727f665f22b48f34bee23f0fad52
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.71e-042001155f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.71e-042001155d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK17A PSME1 ARPC2 TGFB1 FYN

1.71e-04200115594d4f690bf5b87866c0840715396d360b1737d11
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC4A3 PTPRZ1 LRRC8A ALDH3A1 SDK1

1.71e-0420011558827653738a931e4a4545e0c7d75be12bed40740
ToppCellsevere-NK|World / disease stage, cell group and cell class

ARPC2 TGFB1 PIP4K2A MAPK1 FYN

1.71e-042001155320cb0d79adaa1b43d90d027a876cd74f8b55ec3
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAAF11 DNALI1 EFHC1 C6orf118 TMC5

1.71e-042001155cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNALI1 EFHC1 C6orf118 PTPRZ1 TMC5

1.71e-04200115572c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellLPS-IL1RA-Endothelial-Mes-Like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG MROH2A ATCAY CNOT8

2.40e-0411711545a23770806b4612bed4ae6fd716abdec7f7f56c6
DrugPyridazines

MCHR1 MAPK1 MAPK3

1.19e-0731133ctd:D011724
DrugRo 32-0432

ARPC2 TGFB1 MAPK1 MAPK3

5.54e-07141134ctd:C085989
DrugBacterial Toxins

PTPRZ1 MAPK1 MAPK3

1.18e-0651133ctd:D001427
DrugNSC354462

MAP2K4 MAPK1 MAPK3 HSP90AA1

2.10e-06191134CID000434668
Drugdipropionamide

MAPK1 MAPK3 MAPK4

2.36e-0661133CID000138646
Drugdimethyl selenone

MAPK1 MAPK3 MAPK4

2.36e-0661133CID000176413
Drugoctadec-9-en-1-amine

CNOT8 MAPK1 MAPK3 MAPK4

5.66e-06241134CID000008219
Drugthunberginol B

MAPK1 MAPK3 MAPK4

6.55e-0681133CID005473310
Drugcyanidin 3-O-glucoside

MAP2K4 MAPK1 MAPK3 FYN

9.24e-06271134ctd:C114438
Drug6-anilino-5,8-quinolinedione

MAPK1 MAPK3 HSP90AA1

9.78e-0691133ctd:C041715
Drughomoorientin

TGFB1 MAPK1 MAPK3

9.78e-0691133ctd:C057912
DrugCEP-1347

MAP2K4 TGFB1 MAPK1 MAPK3 MAPK4

1.11e-05591135CID000133005
DrugPeroxides

TGFB1 MAPK1 MAPK3

1.39e-05101133ctd:D010545
Drugdelphinidin

TGFB1 MAPK1 MAPK3 FYN

1.86e-05321134ctd:C017185
Drugvanadyl

MAP2K4 MYO7A PTPRZ1 DNAH17 MAPK1 MAPK3 MAPK4 FYN CUX1

2.29e-053071139CID000061671
DrugN-acetyl glycine cysteine amide

MAPK1 MAPK3

2.44e-0521132ctd:C510898
DrugN-acetyl-Cys-Gly-Pro-Cys-amide

MAPK1 MAPK3

2.44e-0521132ctd:C510899
Drugcysteinyl-leukotriene

MAPK1 MAPK3

2.44e-0521132ctd:C112381
DrugNP00111

MAPK1 MAPK3

2.44e-0521132ctd:C530042
Drugsubstance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)-

MAPK1 MAPK3

2.44e-0521132ctd:C496429
Drug7-methyljuglone

MAPK1 MAPK3

2.44e-0521132ctd:C517013
Drugsodium tetrasulfide

MAPK1 MAPK3

2.44e-0521132ctd:C519323
Drug2,2',4,4',5,5'-hexabrominated diphenyl ether

MAPK1 MAPK3

2.44e-0521132ctd:C478854
DrugCGP 56999A

MAPK1 MAPK3

2.44e-0521132ctd:C102659
DrugAG 127

MAPK1 MAPK3

2.44e-0521132ctd:C069028
DrugNF023

MAPK1 MAPK3

2.44e-0521132ctd:C105374
Drugtyrphostin 51

MAPK1 MAPK3

2.44e-0521132ctd:C118515
DrugL 759656

MAPK1 MAPK3

2.44e-0521132ctd:C118949
Drug4-O-methyl-12-O-tetradecanoylphorbol 13-acetate

TGFB1 MAPK1 MAPK3

2.53e-05121133ctd:C020922
DrugAntigens

MAPK1 MAPK3 FYN

2.53e-05121133ctd:D000941
Drug14,15-epoxy-5,8,11-eicosatrienoic acid

TGFB1 MAPK1 MAPK3

2.53e-05121133ctd:C046782
DrugTetracaine

MAPK1 MAPK3 CNGA1

2.53e-05121133ctd:D013748
Drugoleoyl-lysophosphatidic acid

MAP2K4 MCHR1 RBL2 NT5C3A SLC7A7 TGFB1 MAPK1 MAPK3 MAPK4 CUX1

2.57e-0539111310CID000003987
DrugN-(4-aminobutyl)-1-naphthalenesulfonamide

MAPK1 MAPK3 MAPK4

3.28e-05131133CID000005679
DrugLR-90

TGFB1 MAPK1 MAPK3

4.16e-05141133ctd:C485003
Druginchinko-to

TGFB1 MAPK1 MAPK3

4.16e-05141133ctd:C078038
DrugSB202474

MAPK1 MAPK3 MAPK4

4.16e-05141133CID000005162
DrugQuinoxalines

MAPK1 MAPK3 FYN

4.16e-05141133ctd:D011810
DrugProscillaridin A [466-06-8]; Down 200; 7.6uM; HL60; HT_HG-U133A

FPGT SLC7A7 ZBTB14 IVNS1ABP ORC5 POLI FYN

4.62e-0519011372920_DN
Drug2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate

TGFB1 MAPK1 MAPK3

5.19e-05151133ctd:C101670
DrugPQ 401

MAPK1 MAPK3

7.30e-0531132ctd:C569479
Drugcassine

MAPK1 MAPK3

7.30e-0531132ctd:C426663
Drugmanganese(III) acetate dihydrate

MAPK1 MAPK3

7.30e-0531132ctd:C521134
DrugNipaam-ntbam copolymer

MAPK1 MAPK3

7.30e-0531132CID003080965
Drugdelta(4)-tibolone

MAPK1 MAPK3

7.30e-0531132ctd:C485706
DrugtPA stop

MAPK1 MAPK3

7.30e-0531132ctd:C115645
DrugLBT 613

MAPK1 MAPK3

7.30e-0531132ctd:C514877
DrugAAL 881

MAPK1 MAPK3

7.30e-0531132ctd:C514876
DrugNGB 2904

MAPK1 MAPK3

7.30e-0531132ctd:C116818
Drug19-epi-okadaic acid

MAPK1 MAPK3

7.30e-0531132ctd:C522300
Drugalpha-methyl-4-carboxyphenylglycine

MAPK1 MAPK3

7.30e-0531132ctd:C079694
Drug5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole

MAPK1 MAPK3

7.30e-0531132ctd:C534240
DrugYM-254890

MAPK1 MAPK3

7.30e-0531132ctd:C475455
Drugpoly(N-isopropylacrylamide-N-tert-butylacrylamide)copolymer

MAPK1 MAPK3

7.30e-0531132ctd:C079805
Drugcapsanthin

MAPK1 MAPK3

7.30e-0531132ctd:C006889
Drughispidulin

MAPK1 MAPK3

7.30e-0531132ctd:C055957
Drugbromoxynil octanoate

MAPK1 MAPK3

7.30e-0531132ctd:C028382
Drug3,5-diiodothyropropionic acid

MAPK1 MAPK3

7.30e-0531132ctd:C082182
DrugSB 258585

MAPK1 MAPK3

7.30e-0531132ctd:C418570
Drugconnective tissue-activating peptide

MAPK1 MAPK3

7.30e-0531132ctd:C009862
Drugspectaline

MAPK1 MAPK3

7.30e-0531132ctd:C480880
Drugp38alpha inhibitor CMPD1

MAPK1 MAPK3

7.30e-0531132ctd:C492719
DrugOR486

MAPK1 MAPK3

7.30e-0531132ctd:C057726
Drug20(R)-ginsenoside Rg2

RBL2 NT5C3A

7.30e-0531132CID000157711
DrugGW2974

MAPK1 MAPK3

7.30e-0531132ctd:C506645
Drugkaempferol-7-methyl ether

MAPK1 MAPK3

7.30e-0531132ctd:C541117
Drugwogonoside

MAPK1 MAPK3

7.30e-0531132ctd:C473995
DrugGinkgolides

MAPK1 MAPK3

7.30e-0531132ctd:D046934
DrugML 204

MAPK1 MAPK3

7.30e-0531132ctd:C567966
Drughwanggunchungyitang

MAPK1 MAPK3

7.30e-0531132ctd:C539018
DrugBPC96 peptide

MAPK1 MAPK3

7.30e-0531132ctd:C555919
DrugN,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea

MAPK1 MAPK3

7.30e-0531132ctd:C541384
DrugAC1L18JE

SLC7A7 MAPK1 MAPK3

7.69e-05171133CID000050153
DrugN,N'-bis(salicylideneamino)ethane-manganese(II)

TGFB1 MAPK1 MAPK3

7.69e-05171133ctd:C090577
DrugO(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate

MAP2K4 MAPK1 MAPK3

7.69e-05171133ctd:C474958
Drugcalcium silicate

TGFB1 MAPK1 MAPK3

7.69e-05171133ctd:C031293
Drugbicyclol

TGFB1 MAPK1 MAPK3

7.69e-05171133ctd:C477843
DrugRG-13577

TGFB1 MAPK1 MAPK3

7.69e-05171133CID003081306
DrugEndosulfan

MAP2K4 MCF2 XRCC5 MYSM1 SLCO1B7 MAPK1 ALDH3A1 MAPK3 CNGA1 ALOX12B

7.89e-0544711310ctd:D004726
Drugalpha-ketoisovalerate

APOB GTF2IRD1 MAPK1 MAPK3 MAPK4

8.21e-05891135CID000000049
DrugLy-364947

TGFB1 MAPK1 MAPK3

9.20e-05181133ctd:C520284
Drugdiphenyliodonium

TGFB1 MAPK1 MAPK3

9.20e-05181133ctd:C031291
Drug1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole

TGFB1 MAPK1 MAPK3

9.20e-05181133ctd:C524478
DrugDENSPM

RBL2 MAPK1 MAPK3 MAPK4

9.46e-05481134CID000004282
Drugpyrimidin-2-one beta-ribofuranoside

MAPK1 MAPK3 CUX1 HSP90AA1

9.46e-05481134ctd:C009131
DrugNIH-3

MAP2K4 MAPK1 MAPK3

1.09e-04191133CID009822007
DrugFTI 277

RBL2 MAPK1 MAPK3

1.09e-04191133ctd:C096856
DrugMolPort-016-580-972

RBL2 MAPK3 CUX1 HSP90AA1

1.20e-04511134CID009938589
Drugmepyramine

CYP3A7 MAPK1 ALDH3A1 MAPK3 MAPK4 ALOX12B

1.21e-041541136CID000004992
Drugdihydrolipoic acid

TGFB1 MAPK1 MAPK3

1.28e-04201133ctd:C015144
DrugThenoyltrifluoroacetone

TGFB1 MAPK1 MAPK3

1.28e-04201133ctd:D013804
Druginhibitor of p38 kinase

MAP2K4 APOB MAPK1 MAPK3

1.40e-04531134CID000027933
DrugAC1L9K70

TBPL2 KLHL2 XRCC5 MYSM1 ZBTB14 NIPBL HSP90AA1

1.45e-042281137CID000446871
Drugrhenium sulfide

CUX2 CUX1

1.46e-0441132CID000159414
Drugisosalipurposide

MAPK1 MAPK3

1.46e-0441132ctd:C027321
Drugdiacetylbis(4-methylthiosemicarbazonato)copper(II)

MAPK1 MAPK3

1.46e-0441132ctd:C570445
Drug2-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium

MAPK1 MAPK3

1.46e-0441132ctd:C436083
Drug2,3,4,2',3',4'-hexachlorobiphenyl

MAPK1 MAPK3

1.46e-0441132ctd:C014218
Drug3-(phenylsulfonyl)-4-(2-(4-(2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoyl)piperazin-1-yl)ethoxy)-1,2,5-oxadiazole-2-oxide

MAPK1 MAPK3

1.46e-0441132ctd:C559860
DrugPurvalanol

MAPK1 MAPK3

1.46e-0441132DB02733
Diseasecancer (implicated_via_orthology)

CUX2 RBL2 PIP4K2A MAPK1 MAPK3 FYN NIPBL CUX1 HSP90AA1

8.94e-072681129DOID:162 (implicated_via_orthology)
Diseasecongenital disorder of glycosylation Iw (implicated_via_orthology)

STT3A STT3B

1.43e-0521122DOID:0080572 (implicated_via_orthology)
DiseaseCamurati-Engelmann Syndrome

TGFB1 IFT122

1.43e-0521122C0011989
DiseaseSepticemia

TGFB1 MAPK1 MAPK3

1.02e-04241123C0036690
DiseaseSepsis

TGFB1 MAPK1 MAPK3

1.02e-04241123C0243026
DiseaseSevere Sepsis

TGFB1 MAPK1 MAPK3

1.02e-04241123C1719672
DiseasePyemia

TGFB1 MAPK1 MAPK3

1.02e-04241123C0034189
Diseasecolon adenocarcinoma (is_implicated_in)

TGFB1 MAPK1 MAPK3

1.30e-04261123DOID:234 (is_implicated_in)
Diseaseurethral obstruction (biomarker_via_orthology)

TGFB1 MAPK1

1.42e-0451122DOID:12577 (biomarker_via_orthology)
Diseasepulmonary hypertension (is_implicated_in)

TGFB1 MAPK1 MAPK3

2.01e-04301123DOID:6432 (is_implicated_in)
DiseaseCEROID LIPOFUSCINOSIS, NEURONAL, 6

MAPK1 MAPK3

2.12e-0461122C1866282
DiseaseStreptococcal pneumonia

MAPK1 MAPK3

2.12e-0461122C0155862
Diseaselevel of Phosphatidylcholine (18:2_18:2) in blood serum

DOCK7 PLXNA4

2.12e-0461122OBA_2045106
DiseaseCholestasis, Extrahepatic

TGFB1 MAPK1 MAPK3

2.44e-04321123C0005398
Diseaseendometrial adenocarcinoma (is_implicated_in)

MAPK1 MAPK3

2.96e-0471122DOID:2870 (is_implicated_in)
Diseasetriacylglycerol 52:4 measurement

APOB SIK3 ZBTB14

3.47e-04361123EFO_0010416
Diseasecholesteryl esters to total lipids in very large HDL percentage

APOB SIK3 DOCK7

3.47e-04361123EFO_0022257
Diseasecholesteryl esters to total lipids in medium LDL percentage

APOB SIK3 DOCK7

3.76e-04371123EFO_0022252
DiseaseJT interval

MAP2K4 FAM13B SLC4A3 CNNM3 C6orf118 CUX1

3.78e-042481126EFO_0007885
Diseaseinsulinoma (is_marker_for)

TGFB1 CUX1

3.94e-0481122DOID:3892 (is_marker_for)
Diseaseureteral obstruction (implicated_via_orthology)

MAPK1 MAPK3

5.05e-0491122DOID:5199 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in small LDL percentage

APOB SIK3 DOCK7

5.49e-04421123EFO_0022255
Diseasetriglycerides in large LDL measurement

APOB SIK3 DOCK7

5.88e-04431123EFO_0022319
Diseasecholesteryl esters to total lipids in small HDL percentage

APOB SIK3 DOCK7

5.88e-04431123EFO_0022254
Diseasefree cholesterol to total lipids in very small VLDL percentage

APOB SIK3 DOCK7

5.88e-04431123EFO_0022290
Diseaseobesity (is_marker_for)

APOB TGFB1 MAPK1 MAPK3

6.05e-041011124DOID:9970 (is_marker_for)
Diseaselevel of Triacylglycerol (51:3) in blood serum

APOB SIK3

6.30e-04101122OBA_2045163
Diseasesaturated fatty acids measurement

APOB SIK3 DOCK7

6.73e-04451123EFO_0022304
Diseaselipoprotein measurement

APOB SIK3 NAA25 DOCK7

7.00e-041051124EFO_0004732
Diseasetriacylglycerol 54:4 measurement

APOB SIK3 SDK1

7.18e-04461123EFO_0010422
Diseaseintraocular pressure measurement

SUPT3H PCDHGA5 DNALI1 EFHC1 OR4C15 ADPRHL1 ALDH3A1 FYN

7.37e-045091128EFO_0004695
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

APOB SIK3

7.68e-04111122OBA_2045170
Diseaseendometrial adenocarcinoma (is_marker_for)

MAPK1 MAPK3

7.68e-04111122DOID:2870 (is_marker_for)
Diseasepolyunsaturated fatty acids to total fatty acids percentage

APOB SIK3 DOCK7

9.16e-04501123EFO_0022303
DiseaseTrigeminal Neuralgia

MAPK1 MAPK3

9.19e-04121122C0040997
DiseaseSecondary Trigeminal Neuralgia

MAPK1 MAPK3

9.19e-04121122C0393787
DiseaseTrigeminal Neuralgia, Idiopathic

MAPK1 MAPK3

9.19e-04121122C0393786
Diseasephospholipids in very small VLDL measurement

APOB SIK3 DOCK7

9.71e-04511123EFO_0022300
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

APOB SIK3 DOCK7

9.71e-04511123EFO_0022302
Diseasecholesterol to total lipids in small HDL percentage

APOB SIK3 DOCK7

9.71e-04511123EFO_0022240
Diseasephospholipids in medium VLDL measurement

APOB SIK3 DOCK7

1.03e-03521123EFO_0022154
Diseasehematologic cancer (implicated_via_orthology)

CUX2 CUX1

1.08e-03131122DOID:2531 (implicated_via_orthology)
Diseasetriglycerides in HDL measurement

APOB SIK3 DOCK7

1.09e-03531123EFO_0022317
Diseasefree cholesterol to total lipids in small LDL percentage

APOB SIK3 DOCK7

1.09e-03531123EFO_0022286
Diseasecholesteryl esters to total lipids in very large VLDL percentage

APOB SIK3 DOCK7

1.09e-03531123EFO_0022258
Diseasetotal lipids in medium VLDL

APOB SIK3 DOCK7

1.15e-03541123EFO_0022153
Diseasetriglycerides in medium HDL measurement

APOB SIK3 DOCK7

1.15e-03541123EFO_0022321
Diseasecholesterol to total lipids in very large VLDL percentage

APOB SIK3 DOCK7

1.15e-03541123EFO_0022244
Diseasetriglycerides in medium VLDL measurement

APOB SIK3 DOCK7

1.21e-03551123EFO_0022155
Diseasetriglycerides in very large HDL measurement

APOB SIK3 DOCK7

1.21e-03551123EFO_0022324
Diseasecholesterol to total lipids in large HDL percentage

APOB SIK3 DOCK7

1.21e-03551123EFO_0022234
Diseasegastric ulcer (implicated_via_orthology)

MAPK1 MAPK3

1.26e-03141122DOID:10808 (implicated_via_orthology)
Diseasetriglycerides in large VLDL measurement

APOB SIK3 DOCK7

1.27e-03561123EFO_0022178
Diseasetriglycerides in LDL measurement

APOB SIK3 DOCK7

1.27e-03561123EFO_0022320
Diseasetriglycerides in very large VLDL measurement

APOB SIK3 DOCK7

1.27e-03561123EFO_0022325
Diseasetriglycerides to total lipids in medium HDL percentage

APOB SIK3 DOCK7

1.27e-03561123EFO_0022333
Diseasetriglycerides in chylomicrons and extremely large VLDL measurement

APOB SIK3 DOCK7

1.27e-03561123EFO_0022316
Diseasecholesteryl esters to total lipids in medium HDL percentage

APOB SIK3 DOCK7

1.27e-03561123EFO_0022251
Diseasetriglycerides in IDL measurement

APOB SIK3 DOCK7

1.41e-03581123EFO_0022149
Diseasetriacylglycerol 52:3 measurement

APOB SIK3

1.45e-03151122EFO_0010415
Diseasetriglycerides in VLDL measurement

APOB SIK3 DOCK7

1.48e-03591123EFO_0022326
Diseasetriglycerides to total lipids in small LDL percentage

APOB SIK3 DOCK7

1.48e-03591123EFO_0022337
Diseasephospholipids in VLDL measurement

APOB SIK3 DOCK7

1.48e-03591123EFO_0022301
Diseaseconcentration of chylomicrons and extremely large VLDL particles measurement

APOB SIK3 DOCK7

1.48e-03591123EFO_0022260
Diseasebilirubin measurement

UBR1 CUX2 MROH2A APOB OR10Z1 SLCO1B7 DOCK7

1.52e-034421127EFO_0004570
Diseasephospholipids in small VLDL measurement

APOB SIK3 DOCK7

1.56e-03601123EFO_0022146
Diseasetriglycerides to total lipids in large HDL percentage

APOB SIK3 DOCK7

1.56e-03601123EFO_0022330
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

APOB SIK3 DOCK7

1.56e-03601123EFO_0021898
Diseasetotal lipids in VLDL measurement

APOB SIK3 DOCK7

1.56e-03601123EFO_0022314
Diseasecholesterol to total lipids in medium HDL percentage

APOB SIK3 DOCK7

1.56e-03601123EFO_0022237
Diseasepolyunsaturated fatty acid measurement

APOB SIK3 NAA25 DOCK7

1.59e-031311124EFO_0010733
Diseasetriglycerides in small VLDL measurement

APOB SIK3 DOCK7

1.63e-03611123EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

APOB SIK3 DOCK7

1.63e-03611123EFO_0022274
Diseasefree cholesterol in VLDL measurement

APOB SIK3 DOCK7

1.63e-03611123EFO_0022276
Diseasetriglycerides in small HDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022158
Diseasephospholipids in large VLDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022169
Diseasetriglycerides in medium LDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022322
Diseasetriglycerides to total lipids in very large HDL percentage

APOB SIK3 DOCK7

1.71e-03621123EFO_0022339
Diseasetotal lipids in chylomicrons and extremely large VLDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022306
Diseasetotal lipids in very large VLDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022313
Diseasefree cholesterol in chylomicrons and extremely large VLDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022263
Diseasephospholipids in very large VLDL measurement

APOB SIK3 DOCK7

1.71e-03621123EFO_0022299
Diseaseovarian neoplasm

RBL2 MAPK1 MAPK3 ALOX12B

1.73e-031341124C0919267
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

APOB TGFB1 NAA25

1.79e-03631123EFO_0001645, EFO_0004792
Diseasetriglycerides to total lipids in IDL percentage

APOB SIK3 DOCK7

1.79e-03631123EFO_0022329
Diseasefree cholesterol to total lipids in medium LDL percentage

APOB SIK3 DOCK7

1.79e-03631123EFO_0022283
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

APOB SIK3 DOCK7

1.79e-03631123EFO_0022292
DiseaseAstrocytosis

MAPK1 MAPK3

1.87e-03171122C3887640
DiseaseGliosis

MAPK1 MAPK3

1.87e-03171122C0017639
DiseaseMalignant neoplasm of ovary

RBL2 MAPK1 MAPK3 ALOX12B

1.87e-031371124C1140680
Diseasegestational age

MAP2K4 C6orf118 ZNF561 SDK1

1.93e-031381124EFO_0005112
Diseasetriglycerides in small LDL measurement

APOB SIK3 DOCK7

1.96e-03651123EFO_0022323
Diseasecholesterol in large VLDL measurement

APOB SIK3 DOCK7

1.96e-03651123EFO_0021902
Diseasecholesterol in very large VLDL measurement

APOB SIK3 DOCK7

1.96e-03651123EFO_0022230
DiseaseSchizophrenia

MCHR1 BLOC1S1 TGFB1 PTPRZ1 PIP4K2A HAGH MAPK1 ALDH3A1 MAPK3 FYN

1.99e-0388311210C0036341
DiseaseHypertrophy

MAPK1 MAPK3

2.10e-03181122C0020564
Diseasetotal lipids in small VLDL

APOB SIK3 DOCK7

2.14e-03671123EFO_0022148
Diseasetotal lipids in large VLDL

APOB SIK3 DOCK7

2.14e-03671123EFO_0022175
Diseasecholesterol to total lipids in very small VLDL percentage

APOB SIK3 DOCK7

2.14e-03671123EFO_0022245
Diseasetriglycerides in very small VLDL measurement

APOB SIK3 DOCK7

2.23e-03681123EFO_0022144

Protein segments in the cluster

PeptideGeneStartEntry
ELLEKYMDSYDIVLV

NT5C3A

306

Q9H0P0
ILVMVLVDYSITDTY

SLC4A3

936

P48751
LDMRTIATALEYVYK

BLOC1S1

131

P78537
EVYMYQEVDTIELTR

CUX1

936

P39880
YEEVVYVLEEIEYMI

ALDH3A1

61

P30838
RAVIHYRDDETMYVE

ARPC2

141

O15144
YMAAVLEYLTAEILE

H2AC20

51

Q16777
VSEMLRYLETADYAI

AP2A1

406

O95782
YMYREVDTLELTRQV

CUX2

891

O14529
RAEAYLIEEMYDEAI

DNAJC3

346

Q13217
SIIRVEYSLMVYVDI

ARRDC3

281

Q96B67
FILMYEERAVEVACY

MAP2K4

366

P45985
EKARMIYEDYISILS

RGS17

131

Q9UGC6
DNYMYLVIEELTREA

HAGHL

11

Q6PII5
SLDYEESRFYLMEVV

PCDHGA5

306

Q9Y5G8
RTHVEEGDIVYRLYM

LRRC8A

251

Q8IWT6
KTTYYIMRDLEALVT

PGM5

441

Q15124
EMLYYKVLESVIEQE

RBL2

496

Q08999
VYIVQDLMETDLYKL

MAPK1

101

P28482
CLILVVMSYDRYADI

OR2A14

111

Q96R47
TECLLLTVMAYDRYV

OR10AG1

101

Q8NH19
VIVLTAMAYDRYVAI

OR4C15

111

Q8NGM1
DRYAYRDSMTDVIVQ

IFT122

361

Q9HBG6
EMLRDIIREYTDVYP

MAGED1

496

Q9Y5V3
ELVMDEEAYVLYHRA

GRWD1

46

Q9BQ67
DSLEELMEEVQTLYY

IVNS1ABP

211

Q9Y6Y0
AYIVQEYMETDLARL

MAPK4

101

P31152
TAVYYVLADLVMLTL

SLC66A1

101

Q6ZP29
YMYLVIDDETKEAAI

HAGH

61

Q16775
SLELLVAEDYMIVYL

ATCAY

221

Q86WG3
REIYYITEDMSIRIQ

KIAA1109

86

Q2LD37
IVSRIMAGLLENYYE

FAM13B

196

Q9NYF5
LEVIYMIELIDKYCV

HSP90AA5P

201

Q58FG0
TEDRDRMTSVIAYVY

PLXNA4

426

Q9HCM2
VECVLLAVMAYDRYA

OR2W6P

116

Q8NHA6
EGVLLVLMSYDRYVA

OR2Z1

111

Q8NG97
AEQYYDMLIERILDT

NIPBL

1846

Q6KC79
RDVYIVQDLMETDLY

MAPK3

116

P27361
EEGDILYTMYIRQTV

LRRC8E

246

Q6NSJ5
EFVLLAVMAYDRYVA

OR2F1

111

Q13607
RVVYDTMIEKFAVLY

PTPRZ1

336

P23471
AECVLLVVMSYDRYV

OR2J2

111

O76002
IETAREISYLESEMY

EXOC8

71

Q8IYI6
YMAAVLEYLTAEILE

H2AC18

51

Q6FI13
MDRYTFYVLEFLEEI

PIGK

246

Q92643
YSLERDQLIAMTYTV

OR10Z1

266

Q8NGY1
DEDYTYLILRVIGNM

APOB

481

P04114
ALVAEYLSMLEDRKY

DOCK7

1716

Q96N67
YLAEYIRTEMLEGDV

DNAH17

4106

Q9UFH2
DRDSYVRELMTYIEV

FUT10

226

Q6P4F1
VRELMTYIEVDSYGE

FUT10

231

Q6P4F1
AVVSEEPIYIVTEYM

FYN

331

P06241
LLDILETENSYYLVM

HUNK

126

P57058
VLESEEQVLVMYHRY

CUL2

76

Q13617
VKDEYELYMATLLES

C6orf118

291

Q5T5N4
ELAYVIQRYREVHDM

COQ4

151

Q9Y3A0
LDDLYREMVRCYVEI

ADPRHL1

76

Q8NDY3
QIILDLAVYRYMDTS

DNAAF11

316

Q86X45
LAVYRYMDTSLIDVD

DNAAF11

321

Q86X45
EIRMTIAAYQTLYES

DNALI1

156

O14645
VMVRALSELTYDSLY

ALOX12B

466

O75342
VIETEKTLYLIMEYA

MARK3

121

P27448
VRELYTVLLGYRAEM

MCF2

511

P10911
YILTAMAIDRYLATV

MCHR1

201

Q99705
YYLMDDTVEIREVHE

EFHC1

266

Q5JVL4
REDYLVEAMEILELY

IST1

61

P53990
KIREIVLSYSYIAMD

CNOT8

26

Q9UFF9
LEVIYMIEPIDEYCV

HSP90AA1

516

P07900
TYDTVLQLEYLDMVV

CYP3A7

346

P24462
YLLRKMVEEVFDVLY

GTF2IRD1

126

Q9UHL9
RMILYEDDSVQVQYV

C5orf34

6

Q96MH7
RYREMSYKVTELLEE

POLI

126

Q9UNA4
RRYEVIMTAYNIIGE

SDK1

1671

Q7Z5N4
VMEIRNAYAVLYDII

PSME1

216

Q06323
LLRVSYMEIYNETIT

CENPE

126

Q02224
LIYKDVEDMITYREQ

FPGT

581

O14772
MYRLNVDGVEIYVIV

PIP4K2A

181

P48426
EAFILVVMAYDRYVA

OR2AT4

116

A6NND4
AEDRMIRFVEYYLTS

OSBPL11

421

Q9BXB4
ECVLLAVMAYDRYVA

OR2K2

111

Q8NGT1
VEIILLVVMAYDCYV

OR4C5

131

Q8NGB2
LLCYIMETDYVEALT

MROH2A

526

A6NES4
EVSYMEIYNEKVRDL

KIF13A

146

Q9H1H9
SIDEMDLEVRDYYLS

RGSL1

116

A5PLK6
VATEREYVRALEYTM

PLEKHG4

741

Q58EX7
YIVLDKAEYLRDMEA

ORC5

121

O43913
EAYVTDVLYRVMRCV

SMG1

426

Q96Q15
AYEIMRELDVSYVLV

STT3A

566

P46977
VMETERMIYLVTEYA

SIK3

131

Q9Y2K2
MYVDIGYVDLSTIRI

SLCO1B7

186

G3V0H7
LMEEMILYYSVSEER

TDRD7

941

Q8NHU6
EVYETASEMILVLEY

STK17A

126

Q9UEE5
EGYLYVMSRVDDVIN

ACSS3

546

Q9H6R3
YVSDIVYLIDMFVRT

CNGA1

201

P29973
VYEEERSNIVDMLYL

CNNM3

351

Q8NE01
MYETVDEGLKIEVLY

POGLUT3

106

Q7Z4H8
ALLDTTEKYLYRDVM

ZNF561

56

Q8N587
LRSDIFEEVLNYMYT

ZBTB14

81

O43829
KIEGEVRERMLVSYY

WASHC5

156

Q12768
VAMEILAYLAYETVA

SUPT3H

216

O75486
RYSEDDVATYMVQLL

SPEG

3056

Q15772
YKIMRTLDVDYVLVI

STT3B

646

Q8TCJ2
ADYYAKEVTRVLMVE

TGFB1

101

P01137
LTNVAYYTVLDMRDI

SLC7A7

276

Q9UM01
EEMLQVLIYIVGERY

UBR1

741

Q8IWV7
MTREERIEQYTFIYI

NSD3

381

Q9BZ95
LYMEEIEGSVTVRDY

TP53RK

111

Q96S44
LEMLLEYLQDYTDRV

SF3A3

186

Q12874
YLEEVGYTDTILDMR

STRN4

181

Q9NRL3
VERYEMPRHEVYVLL

TMC5

681

Q6UXY8
MQYLELTKREVEYIA

VWA8

121

A3KMH1
YEIFETSDGRIYIIM

TSSK2

76

Q96PF2
DLDMVAIVRYAYDKR

XRCC5

386

P13010
RSMEQEETYLELYLD

TBPL2

31

Q6SJ96
TLRMLIDYVYTAEIQ

KLHL2

106

O95198
YFVDYGSEMILERLL

MYO7A

1396

Q13402
EAEAEVELYYMILER

NAA25

191

Q14CX7
NRAVIEKMLLEEEYY

MYSM1

61

Q5VVJ2