Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H4K20 methyltransferase activity	KMT5C SMYD5 KMT5B	4.34e-05	10	145	3	GO:0042799
GeneOntologyMolecularFunction	adenyl-nucleotide exchange factor activity	HSPH1 GRPEL2 GRPEL1	1.60e-04	15	145	3	GO:0000774
GeneOntologyMolecularFunction	histone H4 methyltransferase activity	KMT5C SMYD5 KMT5B	2.37e-04	17	145	3	GO:0140939
GeneOntologyMolecularFunction	tubulin binding	MAP9 TRAF3IP1 MAP2 HSPH1 CKAP5 WHAMM DST NF1 BRCA2 NAV3 CEP57	2.98e-04	428	145	11	GO:0015631
GeneOntologyMolecularFunction	RNA polymerase III general transcription initiation factor binding	BDP1 ZBTB43	3.11e-04	4	145	2	GO:0001025
GeneOntologyMolecularFunction	histone H4K20me methyltransferase activity	KMT5C KMT5B	3.11e-04	4	145	2	GO:0140941
GeneOntologyMolecularFunction	microtubule binding	MAP9 TRAF3IP1 MAP2 CKAP5 WHAMM DST NF1 NAV3 CEP57	4.27e-04	308	145	9	GO:0008017
GeneOntologyMolecularFunction	histone H4K20 monomethyltransferase activity	KMT5C KMT5B	7.71e-04	6	145	2	GO:0140944
GeneOntologyCellularComponent	microtubule	CUL3 MAP9 DNAH3 SHROOM3 MAP2 HSPH1 CKAP5 WHAMM HID1 TRIP10 DST DPP9 NAV3 CEP57	2.68e-05	533	148	14	GO:0005874
MousePheno	abnormal cell nucleus morphology	MAP9 GLRX3 MCM2 PTPN11 BRCA2 RBM19 ZPR1 CEP57 TP53BP1	1.80e-05	184	113	9	MP:0003111
Domain	GrpE	GRPEL2 GRPEL1	5.74e-05	2	142	2	IPR000740
Domain	GrpE	GRPEL2 GRPEL1	5.74e-05	2	142	2	PF01025
Domain	-	GRPEL2 GRPEL1	5.74e-05	2	142	2	3.90.20.20
Domain	-	GRPEL2 GRPEL1	5.74e-05	2	142	2	2.30.22.10
Domain	GrpE_head	GRPEL2 GRPEL1	5.74e-05	2	142	2	IPR009012
Domain	SAM_MT43_SUVAR420_2	KMT5C KMT5B	5.74e-05	2	142	2	PS51570
Domain	GRPE	GRPEL2 GRPEL1	5.74e-05	2	142	2	PS01071
Domain	Hist-Lys_N-MTase_Suvar4-20	KMT5C KMT5B	5.74e-05	2	142	2	IPR025790
Domain	TOM1	TOM1L2 TOM1	1.71e-04	3	142	2	IPR014645
Domain	ARM-like	SMG1 CAND1 CKAP5 ELMO1 CSE1L NF1 LTN1 NCAPD2 PPP6R3	2.26e-04	270	142	9	IPR011989
Domain	SET	KMT5C SMYD5 KMT2C KMT5B	2.61e-04	41	142	4	PF00856
Domain	ARM-type_fold	SMG1 CAND1 INTS1 CKAP5 ELMO1 CSE1L NF1 LTN1 NCAPD2 PPP6R3	2.72e-04	339	142	10	IPR016024
Domain	SET	KMT5C SMYD5 KMT2C KMT5B	4.08e-04	46	142	4	SM00317
Domain	SET_dom	KMT5C SMYD5 KMT2C KMT5B	5.62e-04	50	142	4	IPR001214
Domain	SET	KMT5C SMYD5 KMT2C KMT5B	5.62e-04	50	142	4	PS50280
Domain	DCN-prot	DCUN1D5 DCUN1D4	5.65e-04	5	142	2	IPR014764
Domain	PONY_dom	DCUN1D5 DCUN1D4	5.65e-04	5	142	2	IPR005176
Domain	DCUN1	DCUN1D5 DCUN1D4	5.65e-04	5	142	2	PS51229
Domain	Cullin_binding	DCUN1D5 DCUN1D4	5.65e-04	5	142	2	PF03556
Domain	ZF_PHD_2	ATRX BPTF KMT2C KDM2A RAI1	7.92e-04	95	142	5	PS50016
Domain	ZF_PHD_1	ATRX BPTF KMT2C KDM2A RAI1	8.31e-04	96	142	5	PS01359
Domain	GAT_dom	TOM1L2 TOM1	8.44e-04	6	142	2	IPR004152
Domain	-	TOM1L2 TOM1	8.44e-04	6	142	2	1.20.58.160
Domain	GAT	TOM1L2 TOM1	8.44e-04	6	142	2	PS50909
Domain	GAT	TOM1L2 TOM1	8.44e-04	6	142	2	PF03127
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYC ABCF1 CAND1 RASA2 LRSAM1 HSPH1 CKAP5 MCM2 PPIB GFPT1 TOE1 BLM TGM3 SAFB CSE1L DST NF1 RBM19 LTN1 NCAPD2 GEMIN4 ZNF638 KDM2A PRR14L MGA TP53BP1	1.16e-10	1353	148	26	29467282
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CUL3 ABCF1 CAND1 MAP2 GLRX3 LRSAM1 HSPH1 TOM1 TBC1D2 MCM2 IDH1 NR3C1 PPIB TRIP10 GFPT1 AKAP12 GRPEL1 PTPN11 MYG1 CSE1L DPP9 RABEP1 ZPR1 NCAPD2 UBA6 PPP6R3	5.47e-10	1455	148	26	22863883
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	TCAF1 ABCF1 CAND1 ZBTB33 HSPH1 TOM1 CKAP5 SMYD5 IDH1 NR3C1 PPIB TRIP10 SLC1A4 GFPT1 AKAP12 TGM3 GRPEL1 PTPN11 SAFB MYG1 RBM19 NCAPD2 UBA6 EPB41 TP53BP1	7.68e-10	1367	148	25	32687490
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ABCF1 INTS1 CKAP5 GFPT1 ITPR3 BLM BPTF TGM3 CSE1L DST NF1 NCAPD2 GEMIN4 ZNF638 TP53BP1 RAI1 PPP6R3	3.17e-09	653	148	17	22586326
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ABCF1 CAND1 ZBTB33 ATRX HSPH1 CKAP5 IDH1 NR3C1 GFPT1 AKAP12 PTPN11 SAFB DST RABEP1 ZNF638 SENP6 PRR14L EPB41 TP53BP1 PPP6R3	3.33e-09	934	148	20	33916271
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG1 ABCF1 ATRX HECTD4 MCM2 TRIP10 GFPT1 LRCH3 ITPR3 BLM NF1 TRMT1L TP53BP1 PPP6R3	6.92e-09	440	148	14	34244565
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CUL3 SMG1 SHROOM3 ZNF609 CAND1 HECTD4 MCM2 KMT2C DST NCAPD2 SENP6 CEP57 RAI1 PPP6R3 ZNF646	9.13e-09	529	148	15	14621295
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	ABCF1 ZBTB33 ATRX CKAP5 BPTF SAFB MYG1 CSE1L NCAPD2 ZNF638 TRMT1L TP53BP1	2.15e-08	332	148	12	32786267
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CUL3 TCAF1 SHROOM3 CAND1 TRAF3IP1 HECTD4 CKAP5 PPIB AKAP12 MAGI2 DST NF1 RABEP1 UBA6 DGKI MGA WNK3 TP53BP1 RAI1	3.12e-08	963	148	19	28671696
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CUL3 MTERF3 ZBTB43 TOM1 INTS1 ZNF316 PPIB ERLEC1 AKAP12 KMT2C PTPN11 FGB DGKI MGA ZNF646 WDR48	4.60e-08	689	148	16	36543142
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MYC GGNBP2 ZNF609 ZBTB33 DCUN1D5 ZC3H8 MTERF3 ZBTB43 NR3C1 DCUN1D4 TOE1 BPTF ZNF638 MGA NFAT5 ZNF513 ZNF646	7.05e-08	808	148	17	20412781
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BDP1 SHROOM3 ZNF609 CAND1 ATRX RASA2 MAP2 ZC3H8 TOM1 HECTD4 LRCH3 FARP2 BPTF KMT2C DPP9 RABEP1 KCNJ3 UBA6 ZNF638 KDM2A NFAT5 EPB41 RAI1	8.78e-08	1489	148	23	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SHROOM3 GGNBP2 ABCF1 CAND1 ATRX HSPH1 TOM1 INTS1 CKAP5 WHAMM TOE1 LRCH3 FARP2 BLM KMT2C DST RBM19 LTN1 NCAPD2 GEMIN4 TRMT1L EPB41 PPP6R3	9.67e-08	1497	148	23	31527615
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GLIPR1 ABCF1 CAND1 VWF TRAF3IP1 ATRX LRSAM1 HSPH1 ZBTB43 HECTD4 CKAP5 DEF8 WHAMM GFPT1 TMED4 MAGI2 DST SACS RABEP1 NAV3 SENP6	1.35e-07	1285	148	21	35914814
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BDP1 ABCF1 MAP2 LRSAM1 HSPH1 PPIB TOE1 BLM KMT2C NCAPD2 UBA6 FGB RAI1	2.35e-07	497	148	13	36774506
Pubmed	Functional proteomics mapping of a human signaling pathway.	TOM1L2 SMG1 ZBTB6 VWF THSD7A ATRX GLRX3 TOM1 MYG1 DST RBM19 UBA6 KDM2A MGA	2.63e-07	591	148	14	15231748
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	MYC CUL3 CAND1 ATRX GLRX3 INTS1 MCM2 SMYD5 GFPT1 BLM BPTF PTPN11 SAFB CSE1L NCAPD2 UBA6 KDM2A TRMT1L	3.50e-07	1014	148	18	32416067
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL3 SMG1 GGNBP2 ZNF609 ABCF1 ATRX NR3C1 FHIP2A FARP2 GRPEL1 DST ZNF638 PZP WDR48	8.16e-07	650	148	14	38777146
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CAND1 ATRX INTS1 MCM2 TOE1 BPTF KMT2C CSE1L NCAPD2 ZNF638 TRMT1L TP53BP1	8.77e-07	469	148	12	27634302
Pubmed	Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.	CUL3 CAND1 DCUN1D5 DCUN1D4	9.20e-07	18	148	4	26906416
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	CUL3 CAND1 MAP2 HSPH1 INTS1 ITPR3 KMT2C CSE1L DST KLHL12	1.33e-06	322	148	10	26514267
Pubmed	A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.	KMT5C KMT5B TP53BP1	1.50e-06	6	148	3	18676810
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	SMG1 TCAF1 ABCF1 MAP2 INTS1 MCM2 GFPT1 DST SACS GEMIN4 EPB41 PPP6R3	1.64e-06	498	148	12	36634849
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	MYC MAP2 NR3C1 AKAP12 LTN1 SENP6 CEP57 TP53BP1	1.75e-06	191	148	8	20195357
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	TOM1L2 CUL3 ABCF1 CAND1 GLRX3 HSPH1 TOM1 CKAP5 MCM2 IDH1 NR3C1 PPIB AKAP12 CSE1L DST NCAPD2 GEMIN4 TRMT1L	2.08e-06	1149	148	18	35446349
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ZBTB33 GLRX3 HSPH1 CKAP5 PPIB GFPT1 AKAP12 PTPN11 CSE1L DST NCAPD2 UBA6 GEMIN4 EPB41	2.21e-06	708	148	14	39231216
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TCAF1 ABCF1 CAND1 GLRX3 HSPH1 CKAP5 MCM2 PPIB TRIP10 GFPT1 TOE1 PTPN11 CSE1L RBM19 NCAPD2 UBA6 GEMIN4 ZNF638 TRMT1L PPP6R3	2.58e-06	1415	148	20	28515276
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	ABCF1 ZBTB33 ATRX MCM2 SAFB RBM19 TRMT1L MGA RAI1 ZNF646	2.73e-06	349	148	10	25665578
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TOM1L2 CUL3 MAP9 ABCF1 CAND1 VWF MAP2 HSPH1 TOM1 CKAP5 BCAS1 PPIB SLC1A4 LRCH3 MAGI2 SAFB CSE1L DST NF1 SACS	3.06e-06	1431	148	20	37142655
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	CUL3 CAND1 DCUN1D5 ZC3H8 ZNF316 ERLEC1 AKAP12 BLM PTPN11 CSE1L LTN1 EPB41	3.28e-06	533	148	12	25544563
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CAND1 ATRX HSPH1 BLM TGM3 PTPN11 SAFB CSE1L BRCA2 MGA	3.33e-06	357	148	10	37059091
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 MAP9 GGNBP2 DRD5 ATRX PCDHGB2 PCDHGA11 HSPH1 MINDY2 PPIB ERLEC1 GRPEL2 BPTF GRPEL1 SAFB DST SACS NCAPD2 CEP57 RAI1	3.43e-06	1442	148	20	35575683
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	VWF AKAP12 ITPR3 BPTF SAFB DST RABEP1 ZNF638 KDM2A TP53BP1	3.59e-06	360	148	10	33111431
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CUL3 ZNF609 ABCF1 TRAF3IP1 ATRX GLRX3 MCM2 AKAP12 TMED4 LRCH3 BLM CSE1L NF1 RABEP1 ZNF638 PRKG2 DNAAF1 TP53BP1 WDR48	3.67e-06	1321	148	19	27173435
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	ABCF1 CAND1 TOM1 PPIB ERLEC1 ITPR3 BLM CSE1L RABEP1	3.98e-06	285	148	9	32838362
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	ABCF1 DCUN1D5 CKAP5 DCUN1D4 ZPR1 TRMT1L MGA EPB41	4.20e-06	215	148	8	35973513
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TCAF1 FARP2 DST SACS LTN1 SENP6	4.87e-06	101	148	6	9872452
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CUL3 ABCF1 ATRX TBC1D2 CKAP5 MCM2 BLM BPTF SAFB NF1 ZNF638 SENP6 TP53BP1 PPP6R3	6.14e-06	774	148	14	15302935
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ZNF609 PPIB BLM BPTF SAFB DST KDM2A TRMT1L EPB41 TP53BP1 PPP6R3	6.18e-06	472	148	11	38943005
Pubmed	Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.	CUL3 CAND1 DCUN1D5	6.23e-06	9	148	3	24192928
Pubmed	Genetic mutations associated with cigarette smoking in pancreatic cancer.	MPL IDH1 PTPN11 NF1 BRCA2	7.51e-06	63	148	5	19351817
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	TCAF1 ATRX HSPH1 INTS1 MCM2 BLM CSE1L ZNF638 TP53BP1 RAI1	7.91e-06	394	148	10	27248496
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SHROOM3 CAND1 ATRX INTS1 CKAP5 BLM CSE1L NF1 NCAPD2 GEMIN4 ZNF638 TRMT1L	7.98e-06	582	148	12	20467437
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ABCF1 CAND1 INTS1 CKAP5 MCM2 PPIB ITPR3 BPTF SAFB CSE1L DST NF1 SACS UBA6 ZNF638 MGA	8.23e-06	1024	148	16	24711643
Pubmed	A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.	KMT5C KMT5B TP53BP1	8.87e-06	10	148	3	27320916
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	CAND1 HSPH1 CKAP5 MCM2 AKAP12 BLM BPTF GRPEL1 CSE1L TP53BP1 PPP6R3	9.46e-06	494	148	11	26831064
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 CAND1 DCUN1D5 HSPH1 CKAP5 MCM2 DCUN1D4 GRPEL1 CSE1L KLHL12 EPB41	9.64e-06	495	148	11	28581483
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ABCF1 CAND1 ATRX HSPH1 CKAP5 MCM2 PPIB GFPT1 TOE1 TGM3 PTPN11 SAFB CSE1L NF1 CLCA2 RBM19 NCAPD2 UBA6 GEMIN4	1.07e-05	1425	148	19	30948266
Pubmed	Human transcription factor protein interaction networks.	MYC SMG1 ZNF609 ZBTB33 ATRX HSPH1 R3HDM2 BLM BPTF KMT2C GRPEL1 CSE1L DST ZNF638 TRMT1L MGA TP53BP1 PPP6R3 WDR48	1.12e-05	1429	148	19	35140242
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	TOM1L2 CUL3 AVEN TCAF1 SHROOM3 LRSAM1 TOM1 TBC1D2 MINDY2 FARP2 RABEP1 PPP6R3	1.16e-05	604	148	12	38803224
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	BDP1 ZBTB33 HECTD4 BPTF RBM19 LTN1 KDM2A TP53BP1	1.26e-05	250	148	8	33536335
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	GGNBP2 ZNF609 CAND1 GJD2 COMP ATRX HSPH1 INTS1 GFPT1 KMT2C PTPN11 SAFB NF1 KMT5B KDM2A MGA PPP6R3 WDR48	1.49e-05	1327	148	18	32694731
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF609 ZBTB33 ATRX PPIB BLM BPTF SAFB BRCA2 RBM19 ZNF638 SENP6 MGA EPB41 TP53BP1 RAI1	1.49e-05	954	148	15	36373674
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	MYC GLIPR1 ZNF609 ZBTB33 INTS1 ZNF316 CKAP5 SLC1A4 BLM SAFB CSE1L NCAPD2 GEMIN4 MGA TP53BP1 PPP6R3 ZNF646	1.55e-05	1203	148	17	29180619
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ABCF1 CAND1 MAP2 ZC3H8 INTS1 HECTD4 PPIB TOE1 BLM BPTF SAFB CSE1L DST SACS ZNF638 PZP	1.62e-05	1082	148	16	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOM1L2 MAP9 TCAF1 ZBTB6 ATRX RASA2 HSPH1 DEF8 AKAP12 KMT2C KCNJ3 LTN1 ZNF638 MGA NFAT5 TP53BP1	1.66e-05	1084	148	16	11544199
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 CCDC73 HSPH1 TBC1D2 INTS1 ZNF316 CKAP5 TSPYL6 ERLEC1 GFPT1 KMT2C DST RAI1	1.71e-05	736	148	13	29676528
Pubmed	The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.	KMT5C KMT5B	1.80e-05	2	148	2	28114273
Pubmed	Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition.	MYC BTK	1.80e-05	2	148	2	28368423
Pubmed	Preferential dimethylation of histone H4 lysine 20 by Suv4-20.	KMT5C KMT5B	1.80e-05	2	148	2	18296440
Pubmed	H3K27M, IDH1, and ATRX expression in pediatric GBM and their clinical and prognostic significance.	ATRX IDH1	1.80e-05	2	148	2	31152217
Pubmed	A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases.	KMT5C KMT5B	1.80e-05	2	148	2	24049080
Pubmed	Preferential binding of ADP-bound mitochondrial HSP70 to the nucleotide exchange factor GRPEL1 over GRPEL2.	GRPEL2 GRPEL1	1.80e-05	2	148	2	39445986
Pubmed	Kaiso represses the expression of glucocorticoid receptor via a methylation-dependent mechanism and attenuates the anti-apoptotic activity of glucocorticoids in breast cancer cells.	ZBTB33 NR3C1	1.80e-05	2	148	2	26424557
Pubmed	GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.	MYC GLIPR1	1.80e-05	2	148	2	22025562
Pubmed	Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.	KMT5C KMT5B	1.80e-05	2	148	2	28778956
Pubmed	Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma.	ATRX IDH1	1.80e-05	2	148	2	29545335
Pubmed	Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma.	MYC MGA	1.80e-05	2	148	2	31862696
Pubmed	Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomas.	ATRX IDH1	1.80e-05	2	148	2	26918938
Pubmed	Expression of granulosa cell microRNAs, AVEN and ATRX are associated with human blastocyst development.	AVEN ATRX	1.80e-05	2	148	2	29693772
Pubmed	Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes.	TOM1L2 RAI1	1.80e-05	2	148	2	10036180
Pubmed	Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.	KMT5C KMT5B	1.80e-05	2	148	2	17846168
Pubmed	Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells.	KMT5C KMT5B	1.80e-05	2	148	2	22022429
Pubmed	Comparative analyses of SUV420H1 isoforms and SUV420H2 reveal differences in their cellular localization and effects on myogenic differentiation.	KMT5C KMT5B	1.80e-05	2	148	2	21206904
Pubmed	Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis.	VWF NFAT5	1.80e-05	2	148	2	24733925
Pubmed	Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.	KMT5C KMT5B	1.80e-05	2	148	2	24396869
Pubmed	NF1 gene mutations represent the major molecular event underlying neurofibromatosis-Noonan syndrome.	PTPN11 NF1	1.80e-05	2	148	2	16380919
Pubmed	Combined ATRX/IDH1 immunohistochemistry predicts genotype of oligoastrocytomas.	ATRX IDH1	1.80e-05	2	148	2	26016385
Pubmed	WD repeat domain 48 promotes hepatocellular carcinoma progression by stabilizing c-Myc.	MYC WDR48	1.80e-05	2	148	2	36403194
Pubmed	Mouse oocyte meiosis is disturbed by knockdown of Suv4-20h.	KMT5C KMT5B	1.80e-05	2	148	2	22951141
Pubmed	The zinc finger protein ZNF297B interacts with BDP1, a subunit of TFIIIB.	BDP1 ZBTB43	1.80e-05	2	148	2	16542149
Pubmed	Noninvasive Prediction of IDH1 Mutation and ATRX Expression Loss in Low-Grade Gliomas Using Multiparametric MR Radiomic Features.	ATRX IDH1	1.80e-05	2	148	2	30194745
Pubmed	Independent NF1 and PTPN11 mutations in a family with neurofibromatosis-Noonan syndrome.	PTPN11 NF1	1.80e-05	2	148	2	19449407
Pubmed	SUV4-20 activity in the preimplantation mouse embryo controls timely replication.	KMT5C KMT5B	1.80e-05	2	148	2	27920088
Pubmed	Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function.	MYC HSPH1	1.80e-05	2	148	2	26887051
Pubmed	A protein interaction landscape of breast cancer.	TOM1L2 AVEN CAND1 HSPH1 TOM1 IDH1 ITPR3 DST BRCA2 TRMT1L PPP6R3 WDR48	1.86e-05	634	148	12	34591612
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	MYC TOM1L2 MAGEA2 CAND1 TOM1 HECTD4 MCM2 CSE1L	1.87e-05	264	148	8	32814769
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	TOM1L2 MAP2 HSPH1 BCAS1 SLC1A4 MAGI2 DST NF1 SACS	1.92e-05	347	148	9	17114649
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SMG1 GGNBP2 RASA2 NR3C1 DCUN1D4 GFPT1 GRPEL2 ITPR3 NBPF15 NF1 DNAAF1 RAI1	1.98e-05	638	148	12	31182584
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	THSD7A CKAP5 MAGI2 DST NFAT5 CEP57	2.07e-05	130	148	6	12421765
Pubmed	Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.	CUL3 DCUN1D5 DCUN1D4	2.09e-05	13	148	3	23201271
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	CAND1 CKAP5 GFPT1 SAFB CSE1L DST MGA PPP6R3	2.25e-05	271	148	8	25737280
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	TOM1L2 CAND1 HSPH1 TOM1 CKAP5 AKAP12 CSE1L RABEP1 NCAPD2 EPB41	2.43e-05	449	148	10	31732153
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ZBTB33 BPTF KMT2C PTPN11 RABEP1 NCAPD2 KDM2A MGA EPB41 TP53BP1 PPP6R3	2.51e-05	549	148	11	38280479
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CUL3 ABCF1 HSPH1 CKAP5 PPIB GFPT1 TOE1 LRCH3 ITPR3 TGM3 SAFB CSE1L DST RBM19 GEMIN4 ZNF638 TRMT1L	2.71e-05	1257	148	17	36526897
Pubmed	A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.	MYC CUL3 CAND1 KLHL12 TP53BP1	3.07e-05	84	148	5	34591642
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	CUL3 ZBTB33 CKAP5 NR3C1 BPTF CSE1L RBM19 ZNF638 TRMT1L	3.17e-05	370	148	9	22922362
Pubmed	Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.	KMT5C KMT2C KMT5B	3.31e-05	15	148	3	35907431
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	ZBTB33 ATRX BPTF ZNF638 MGA	3.44e-05	86	148	5	37253089
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	CUL3 SHROOM3 CAND1 NR3C1 KLHL12	3.64e-05	87	148	5	37495603
Interaction	SUMO2 interactions	MYC CUL3 ABCF1 ZBTB33 ATRX CKAP5 PPIB BLM BPTF SAFB MYG1 CSE1L DST NCAPD2 ZNF638 SENP6 TRMT1L TP53BP1	3.22e-07	591	147	18	int:SUMO2
Interaction	NAA40 interactions	CUL3 ABCF1 CAND1 ZBTB33 ATRX GLRX3 HSPH1 CKAP5 MCM2 IDH1 NR3C1 GFPT1 AKAP12 PTPN11 SAFB DST RABEP1 ZNF638 SENP6 PRR14L EPB41 TP53BP1 PPP6R3	6.60e-07	978	147	23	int:NAA40
Interaction	C3orf18 interactions	SMG1 DCUN1D5 INTS1 CKAP5 NF1 SACS LTN1 GEMIN4	2.03e-06	115	147	8	int:C3orf18
Interaction	FBXO22 interactions	MYC CUL3 BDP1 ABCF1 MAP2 LRSAM1 HSPH1 PPIB TOE1 BLM KMT2C NCAPD2 UBA6 FGB TP53BP1 RAI1	2.17e-06	540	147	16	int:FBXO22
Interaction	ASH2L interactions	MYC CUL3 BDP1 NR3C1 KMT2C BRCA2 SACS KDM2A MGA TP53BP1 PPP6R3	4.04e-06	265	147	11	int:ASH2L
Interaction	DYNLRB1 interactions	MYC CUL3 MAGEA2 ATRX HSPH1 AKAP12 SAFB	4.97e-06	92	147	7	int:DYNLRB1
Interaction	NOSIP interactions	MYC CUL3 MCM2 NR3C1 PTPN11 NF1 TP53BP1	6.15e-06	95	147	7	int:NOSIP
Interaction	CCND1 interactions	MYC CUL3 HSPH1 TBC1D2 MCM2 CSE1L BRCA2 RABEP1 KDM2A MGA CEP57	8.33e-06	286	147	11	int:CCND1
Interaction	KCNA3 interactions	ADCY10 ZBTB33 CCDC73 GLRX3 HSPH1 CKAP5 PPIB GFPT1 AKAP12 KMT2C PTPN11 CSE1L DST NCAPD2 UBA6 GEMIN4 SENP6 EPB41 TDRD12	1.96e-05	871	147	19	int:KCNA3
Interaction	USP21 interactions	CUL3 LRSAM1 CKAP5 PPIB NF1 BRCA2 ZNF638 PPP6R3	2.43e-05	161	147	8	int:USP21
Interaction	UIMC1 interactions	CUL3 BLM NF1 BRCA2 CEP57 TP53BP1 WDR48	3.00e-05	121	147	7	int:UIMC1
Interaction	DRD4 interactions	CUL3 INTS1 KCNJ3 KLHL12	3.05e-05	25	147	4	int:DRD4
Interaction	SIRT7 interactions	ABCF1 INTS1 CKAP5 GFPT1 ITPR3 BLM BPTF TGM3 CSE1L DST NF1 NCAPD2 GEMIN4 ZNF638 TP53BP1 RAI1 PPP6R3	3.11e-05	744	147	17	int:SIRT7
Interaction	RASA2 interactions	MYC RASA2 NR3C1 TOE1	3.59e-05	26	147	4	int:RASA2
Interaction	DCUN1D4 interactions	CUL3 CAND1 NR3C1 DCUN1D4	4.19e-05	27	147	4	int:DCUN1D4
Interaction	H4C2 interactions	CUL3 CAND1 ATRX MCM2 KMT5B	4.57e-05	54	147	5	int:H4C2
Interaction	CDC5L interactions	MYC CUL3 SHROOM3 CAND1 TRAF3IP1 INTS1 CKAP5 ERLEC1 CSE1L DST NF1 ZNF35 NCAPD2 GEMIN4 ZNF638 SENP6 TRMT1L PPP6R3	5.23e-05	855	147	18	int:CDC5L
Interaction	BPIFB4 interactions	BRCA2 BPIFB4	5.28e-05	2	147	2	int:BPIFB4
Interaction	WEE1 interactions	MYC ATRX ZNF316 MCM2 NR3C1 BLM BRCA2	5.50e-05	133	147	7	int:WEE1
Interaction	SIRT6 interactions	SMG1 ABCF1 ATRX HECTD4 MCM2 TRIP10 GFPT1 LRCH3 ITPR3 BLM NF1 NCAPD2 TRMT1L TP53BP1 PPP6R3	5.70e-05	628	147	15	int:SIRT6
Interaction	SMC1A interactions	MYC CUL3 MAGEA9 ATRX CKAP5 MCM2 NR3C1 BLM BPTF BRCA2 MGA TP53BP1	5.84e-05	418	147	12	int:SMC1A
Interaction	GRPEL2 interactions	CUL3 NR3C1 GRPEL2 GRPEL1	6.42e-05	30	147	4	int:GRPEL2
Interaction	RCOR1 interactions	MYC CUL3 ZBTB33 CKAP5 NR3C1 DST BRCA2 RABEP1 NCAPD2 GEMIN4 MGA TP53BP1 PPP6R3	6.93e-05	494	147	13	int:RCOR1
Interaction	RNMT interactions	MYC CUL3 CAND1 ATRX MCM2 TP53BP1	6.93e-05	95	147	6	int:RNMT
Interaction	SHPRH interactions	CUL3 MAGEA9 PPIB BPTF EDARADD NFAT5	7.79e-05	97	147	6	int:SHPRH
Interaction	DHX40 interactions	MYC GLRX3 ZC3H8 NR3C1 BLM SAFB ZNF638 MGA RAI1	9.09e-05	249	147	9	int:DHX40
Interaction	SLFN11 interactions	CUL3 BDP1 ZBTB33 HECTD4 NR3C1 TOE1 BPTF RBM19 LTN1 KDM2A TP53BP1	1.01e-04	376	147	11	int:SLFN11
Interaction	PRNP interactions	MYC TOM1L2 CUL3 GLRX3 MTERF3 ZBTB43 TOM1 INTS1 ZNF316 BCAS1 PPIB ERLEC1 AKAP12 MAGI2 KMT2C PTPN11 FGB DGKI MGA ZNF646 WDR48	1.03e-04	1158	147	21	int:PRNP
Interaction	DNAAF1 interactions	GLRX3 NR3C1 DNAAF1	1.03e-04	13	147	3	int:DNAAF1
Interaction	EED interactions	MYC CUL3 SHROOM3 ABCF1 CAND1 GLRX3 HSPH1 TOM1 INTS1 CKAP5 MCM2 PPIB GFPT1 BPTF SAFB CSE1L RBM19 LTN1 NCAPD2 UBA6 ZNF638 KDM2A MGA TP53BP1	1.23e-04	1445	147	24	int:EED
Interaction	H4C9 interactions	CUL3 CAND1 ATRX MCM2 BPTF KDM2A	1.41e-04	108	147	6	int:H4C9
Interaction	RPL23A interactions	MYC CUL3 CAND1 MAP2 ZC3H8 KMT5C MCM2 TOE1 BLM SAFB DST RBM19 TRMT1L RAI1	1.44e-04	606	147	14	int:RPL23A
Interaction	UBE2L3 interactions	MYC HECTD4 MCM2 NR3C1 ZPR1 LTN1 UBA6 TP53BP1	1.62e-04	211	147	8	int:UBE2L3
Interaction	HDAC1 interactions	MYC CUL3 ZNF609 ZBTB33 ATRX HSPH1 ZBTB43 CKAP5 NR3C1 LRCH3 BPTF DST BRCA2 RABEP1 NCAPD2 GEMIN4 ZNF638 MGA RAI1 PPP6R3	1.63e-04	1108	147	20	int:HDAC1
Interaction	MYO6 interactions	MYC TOM1L2 CUL3 SHROOM3 HSPH1 TOM1 NR3C1 LRCH3 DPP9 GEMIN4 ZNF638	1.67e-04	398	147	11	int:MYO6
Interaction	AMPD1 interactions	CUL3 CAND1 NR3C1	1.99e-04	16	147	3	int:AMPD1
Interaction	ZSWIM8 interactions	CUL3 R3HDM2 TSPYL6 FARP2 PRG2	2.07e-04	74	147	5	int:ZSWIM8
Interaction	TERF2IP interactions	MYC CUL3 ZNF609 INTS1 MCM2 BLM BPTF BRCA2 ZNF638 SENP6 MGA RAI1 PPP6R3	2.08e-04	552	147	13	int:TERF2IP
Interaction	BAP1 interactions	MYC TOM1L2 CUL3 ABCF1 CAND1 GLRX3 HSPH1 TOM1 CKAP5 MCM2 IDH1 NR3C1 PPIB AKAP12 ITPR3 KMT2C CSE1L DST BRCA2 NCAPD2 GEMIN4 TRMT1L	2.18e-04	1314	147	22	int:BAP1
Interaction	H4C8 interactions	CUL3 CAND1 MCM2 CEP57	2.23e-04	41	147	4	int:H4C8
Interaction	CALR interactions	CUL3 BDP1 VWF MCM2 NR3C1 PPIB KMT2C PTPN11 NCAPD2 FGB EPB41	2.34e-04	414	147	11	int:CALR
Interaction	TNFSF13B interactions	CAND1 FHIP2A CSE1L NF1 NCAPD2 GEMIN4	2.40e-04	119	147	6	int:TNFSF13B
GeneFamily	Neuroblastoma breakpoint family	NBPF19 NBPF15 NBPF7P	2.53e-04	23	98	3	662
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT5C KMT2C KMT5B	8.18e-04	34	98	3	487
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	SMG1 CKAP5 BPTF KMT2C NF1 NCAPD2 KDM2A PRR14L NFAT5	8.98e-07	180	148	9	M8239
Coexpression	MURARO_PANCREAS_BETA_CELL	TCAF1 ZBTB33 ATRX MAP2 HSPH1 HECTD4 WHAMM NR3C1 SLC1A4 GFPT1 ELMO1 GRPEL2 ITPR3 KMT2C PTPN11 DST RABEP1 EDARADD KLHL12	1.71e-06	946	148	19	M39169
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	MYC CAND1 ATRX CKAP5 R3HDM2 NR3C1 DCUN1D4 BLM BPTF CSE1L DST BRCA2 SACS LTN1 NAV3 ZNF638 TP53BP1	7.25e-06	856	148	17	M4500
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	CUL3 GLRX3 HSPH1 CKAP5 MCM2 SLC1A4 GFPT1 AKAP12 ITPR3 BLM GRPEL1 PTPN11 SAFB BRCA2 ZPR1 CRLF3 DENND2C NCAPD2 GEMIN4 SENP6 EPB41	1.23e-05	1290	148	21	M80
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	SMG1 ZNF609 ZBTB33 ATRX GLRX3 HSPH1 MTERF3 INTS1 NR3C1 SLC1A4 LRCH3 GRPEL1 PTPN11 CSE1L SACS BTK LTN1 SENP6 NFAT5 CEP57	1.72e-05	1215	148	20	M41122
Coexpression	HALLMARK_MITOTIC_SPINDLE	RASA2 CKAP5 DST NF1 BRCA2 GEMIN4 CEP57 EPB41	1.82e-05	199	148	8	M5893
Coexpression	GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN	MYC CUL3 BDP1 CAND1 RASA2 GFPT1 BLM SENP6	1.82e-05	199	148	8	M6932
Coexpression	GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	ADCY10 ZNF609 ABCF1 INTS1 MCM2 SMYD5 BPTF GEMIN4	1.89e-05	200	148	8	M7256
Coexpression	GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_DN	CKAP5 IDH1 BLM MAGI2 BRCA2 RABEP1 KCNJ3 BTK	1.89e-05	200	148	8	M5225
Coexpression	PUJANA_ATM_PCC_NETWORK	MYC GLIPR1 MYF6 MAGEA9 ZBTB6 ZBTB33 COMP INTS1 MCM2 NR3C1 SLC1A4 TOE1 BLM BPTF SAFB RABEP1 CRLF3 BTK NCAPD2 CEP57 EPB41	3.85e-05	1394	148	21	M9585
Coexpression	PHONG_TNF_RESPONSE_VIA_P38_COMPLETE	GLIPR1 TCAF1 IDH1 NR3C1 GFPT1 RBM19 NAV3 KDM2A	4.24e-05	224	148	8	M2500
Coexpression	GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP	SMG1 MINDY2 ERLEC1 BPTF PTPN11 KMT5B NCAPD2	4.73e-05	167	148	7	M365
Coexpression	WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN	MYC DCUN1D5 HSPH1 MCM2 SLC1A4 TOE1 BLM GEMIN4 ALDH1A3 WDR48	5.17e-05	371	148	10	M2132
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	GLIPR1 BDP1 TCAF1 GGNBP2 ZC3H8 HSPH1 MTERF3 BLM BPTF SACS RABEP1 ZNF638 CEP57	9.33e-05	656	148	13	M18979
Coexpression	PUJANA_CHEK2_PCC_NETWORK	MYC ZBTB33 HSPH1 MCM2 SLC1A4 TOE1 BLM CSE1L NF1 ZNF35 BRCA2 NCAPD2 CEP57 EPB41	1.09e-04	761	148	14	M11961
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN	GLIPR1 ZBTB43 R3HDM2 ITPR3 RABEP1 KDM2A PRR14L	1.33e-04	197	148	7	M3193
Coexpression	GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP	GADD45B ZBTB43 TOM1 NR3C1 LRCH3 TP53BP1 PPP6R3	1.37e-04	198	148	7	M4462
Coexpression	GSE369_IFNG_KO_VS_WT_LIVER_UP	ATRX MINDY2 KMT5B EDARADD NCAPD2 PRR14L RAI1	1.42e-04	199	148	7	M5970
Coexpression	GSE14308_TH17_VS_INDUCED_TREG_UP	GGNBP2 ZBTB33 ATRX ERLEC1 MAGI2 SACS NFAT5	1.46e-04	200	148	7	M3385
Coexpression	GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_DN	TCAF1 HECTD4 CKAP5 IDH1 MINDY2 NCAPD2 CEP57	1.46e-04	200	148	7	M9952
Coexpression	GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN	ATRX HSPH1 BPTF KMT5B CRLF3 LTN1 SENP6	1.46e-04	200	148	7	M4979
Coexpression	GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN	AVEN TCAF1 CAND1 CSE1L BTK TRMT1L ZNF646	1.46e-04	200	148	7	M7686
Coexpression	BROWNE_HCMV_INFECTION_8HR_DN	MYC DST SACS NAV3	1.57e-04	48	148	4	M7846
Coexpression	SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP	MYC GRPEL1 ZPR1 GEMIN4	1.57e-04	48	148	4	M14278
Coexpression	RICKMAN_METASTASIS_UP	CAND1 ZBTB33 ATRX CKAP5 IDH1 FARP2 MAGI2 MGA TP53BP1	1.75e-04	350	148	9	M9752
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	BDP1 ABCF1 THSD7A TRAF3IP1 ATRX HSPH1 CKAP5 DST BRCA2 RABEP1 UBA6 ZNF638 TRMT1L CEP57 EPB41	7.33e-07	469	144	15	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	CUL3 BDP1 ABCF1 HSPH1 CKAP5 SAFB CSE1L BRCA2 RABEP1 UBA6 ZNF638 TRMT1L CEP57 EPB41	1.62e-05	532	144	14	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	BDP1 TRAF3IP1 ATRX HSPH1 CKAP5 SAFB BRCA2 RABEP1	5.09e-05	192	144	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	BDP1 TCAF1 ABCF1 TRAF3IP1 ATRX CKAP5 BLM SAFB BRCA2 RABEP1	5.35e-05	311	144	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	HECTD4 R3HDM2 BPTF CRLF3 EDARADD NFAT5 CCDC65	3.01e-06	186	148	7	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HECTD4 R3HDM2 BPTF CRLF3 EDARADD NFAT5 CCDC65	3.01e-06	186	148	7	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 DNAH3 CFAP251 TRAF3IP1 BCAS1 DNAAF1 CCDC65	3.59e-06	191	148	7	acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZNF609 ELMO1 NBPF19 KMT2C DGKI NFAT5 PPP6R3	3.85e-06	193	148	7	779276e775cb2492e8dd36436295a536084a6415
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MAP9 CAND1 ZBTB33 ATRX CKAP5 BPTF MGA	3.85e-06	193	148	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	BDP1 CKAP5 ERLEC1 CSE1L DPP9 TRMT1L MGA	4.26e-06	196	148	7	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	ATRX HSPH1 PPIB AKAP12 BPTF PTPN11 RABEP1	4.70e-06	199	148	7	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	ZBTB33 CKAP5 SLC1A4 CSE1L RBM19 NCAPD2 TRMT1L	4.86e-06	200	148	7	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BDP1 SMG1 ATRX BPTF KMT2C KDM2A EPB41	4.86e-06	200	148	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF HID1 ELMO1 GRPEL2 BPIFB4 NAV3	1.39e-05	156	148	6	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCNI2 SHROOM3 LRRC9 KCNJ3 EDARADD DGKI	1.84e-05	164	148	6	d847d509bb1791638032ade6755d8164586b5bd5
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-4\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZC3H8 CKAP5 R3HDM2 SAFB CSE1L RBM19	1.97e-05	166	148	6	52293b8a74d46e6161fb6a2e7e86e51fd9e89a5b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCNI2 SHROOM3 LRRC9 KCNJ3 EDARADD DGKI	1.97e-05	166	148	6	6fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCNI2 SHROOM3 THSD7A KCNJ3 EDARADD DGKI	2.74e-05	176	148	6	cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CKAP5 NR3C1 KMT5B KCNJ3 ZNF638	2.74e-05	176	148	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 HSPH1 DENND2C UBA6 ALDH1A3 RAI1	3.01e-05	179	148	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF THSD7A ITPR3 BLM DST CCDC65	3.62e-05	185	148	6	87151ab95530e70d61328b336518df58db584acb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 THSD7A MAP2 DST DGKI NFAT5	3.73e-05	186	148	6	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 TRAF3IP1 ATRX LTN1 TRMT1L NFAT5	3.73e-05	186	148	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 HSPH1 KMT2C NF1 NFAT5 TP53BP1	3.96e-05	188	148	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 THSD7A MAP2 DST DGKI NFAT5	3.96e-05	188	148	6	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CKAP5 BLM CSE1L BRCA2 CRLF3 NCAPD2	4.20e-05	190	148	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 DNAH3 CFAP251 BCAS1 DNAAF1 CCDC65	4.32e-05	191	148	6	1e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 DNAH3 CFAP251 BCAS1 DNAAF1 CCDC65	4.32e-05	191	148	6	8688708c9183ebcb200596501dc30cc12073f151
ToppCell	E16.5-Epithelial-Epithelial_Airway\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 DNAH3 CFAP251 BCAS1 DNAAF1 CCDC65	4.45e-05	192	148	6	bb7eb51bc079acacde42d8e55ba06d03eba2ea28
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAP9 CAND1 LRSAM1 GFPT1 MYG1 KLHL12	4.45e-05	192	148	6	efbd52b3d2b6d3fb9ed6bc3f36aca9f4f1fcbc49
ToppCell	(5)_Epithelial_cells-(5)_Epi_upper\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SHROOM3 BCAS1 TRIP10 GRPEL2 TGM3 ALDH1A3	4.45e-05	192	148	6	69b6b3ceaad6432c46d1bc2a00b8389069a8876e
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 DNAH3 CFAP251 BCAS1 DNAAF1 CCDC65	4.45e-05	192	148	6	a50a6279371b3be682e334082637b7ab76b9a6e5
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP9 DNAH3 CFAP251 TRAF3IP1 DNAAF1 CCDC65	4.58e-05	193	148	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHROOM3 TBC1D2 HID1 BCAS1 ITPR3 CLCA2	4.58e-05	193	148	6	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHROOM3 TBC1D2 HID1 BCAS1 ITPR3 CLCA2	4.58e-05	193	148	6	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 HSPH1 BPTF ZNF638 NFAT5 PPP6R3	4.58e-05	193	148	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP9 DNAH3 CFAP251 TRAF3IP1 DNAAF1 CCDC65	4.85e-05	195	148	6	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 THSD7A MAP2 TBC1D2 DST PRKG2	4.85e-05	195	148	6	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 THSD7A PCDHGA11 AKAP12 KMT2C EPB41	5.14e-05	197	148	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CFAP251 TRAF3IP1 BCAS1 DNAAF1 CCDC65	5.28e-05	198	148	6	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	ATRX HSPH1 BCAS1 PPIB BPTF PTPN11	5.43e-05	199	148	6	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	GPR22 ATRX MAP2 MAGI2 BPTF DST	5.43e-05	199	148	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	GPR22 ATRX MAP2 MAGI2 BPTF DST	5.43e-05	199	148	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VWF ATRX HID1 BPTF KMT2C DST	5.58e-05	200	148	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYC ARHGEF19 TOM1 TOE1 GEMIN4 SDS	5.58e-05	200	148	6	88d713dfc792e7609bf7ecfb28f87cb748088570
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H8 MINDY2 ELMO1 UBA6 TP53BP1	6.63e-05	127	148	5	39fa20a55de3af1a62ab5dfa4877879db3935ac2
Computational	Genes upregulated in subsets of cells of a given type within various tumors	BDP1 PTPN11 DST ZNF638 SENP6	7.89e-05	50	96	5	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Disease	MYELODYSPLASTIC SYNDROME	MPL MYC ATRX BLM PTPN11 BRCA2	8.76e-07	67	142	6	C3463824
Disease	juvenile myelomonocytic leukemia (is_implicated_in)	AKAP12 PTPN11 NF1	3.77e-06	7	142	3	DOID:0050458 (is_implicated_in)
Disease	triglyceride measurement, intermediate density lipoprotein measurement	SHROOM3 R3HDM2 BPTF BRCA2 ZPR1 TP53BP1	1.67e-05	111	142	6	EFO_0004530, EFO_0008595
Disease	cystatin C measurement	CCNI2 SHROOM3 CCDC73 HECTD4 R3HDM2 BCAS1 TGM3 PTPN11 NFAT5 TDRD12	2.65e-05	402	142	10	EFO_0004617
Disease	melanoma	CUL3 RASA2 FHIP2A NF1 BRCA2 ALDH1A3 EPB41 RAI1	2.83e-05	248	142	8	C0025202
Disease	high grade glioma (is_implicated_in)	ATRX IDH1 NF1 BRCA2	4.99e-05	42	142	4	DOID:3070 (is_implicated_in)
Disease	Maffucci Syndrome	IDH1 PTPN11	6.88e-05	3	142	2	C0024454
Disease	JUVENILE MYELOMONOCYTIC LEUKEMIA	PTPN11 NF1	1.37e-04	4	142	2	607785
Disease	Enchondromatosis	IDH1 PTPN11	1.37e-04	4	142	2	C0014084
Disease	Juvenile myelomonocytic leukemia	PTPN11 NF1	1.37e-04	4	142	2	cv:C0349639
Disease	Colorectal Carcinoma	MYC DNAH3 MAP2 IDH1 AKAP12 KMT2C CSE1L NF1 SACS PRG2 KDM2A PZP	1.56e-04	702	142	12	C0009402
Disease	Leukemia, Myelocytic, Acute	MYC IDH1 BLM KMT2C PTPN11 NF1	1.97e-04	173	142	6	C0023467
Disease	Glioblastoma Multiforme	MYC ATRX IDH1 NF1 TP53BP1	2.05e-04	111	142	5	C1621958
Disease	Noonan Syndrome	RASA2 PTPN11 NF1	2.05e-04	24	142	3	C0028326
Disease	Burkitt lymphoma (is_implicated_in)	MYC BTK	2.28e-04	5	142	2	DOID:8584 (is_implicated_in)
Disease	juvenile myelomonocytic leukemia (implicated_via_orthology)	PTPN11 NF1	2.28e-04	5	142	2	DOID:0050458 (implicated_via_orthology)
Disease	Anaplastic astrocytoma	IDH1 PTPN11 NF1	2.93e-04	27	142	3	C0334579
Disease	sexual dimorphism measurement	GADD45B RASA2 NR3C1 DCUN1D4 FARP2 BPTF NF1 ZPR1 CRLF3 ZNF638 KDM2A PRKG2 MGA TP53BP1 PPP6R3	2.97e-04	1106	142	15	EFO_0021796
Disease	triglycerides in very small VLDL measurement	R3HDM2 BPTF ZPR1 TP53BP1	3.30e-04	68	142	4	EFO_0022144
Disease	essential thrombocythemia (is_implicated_in)	MPL VWF	3.41e-04	6	142	2	DOID:2224 (is_implicated_in)
Disease	Acute Myeloid Leukemia, M1	MYC IDH1 KMT2C PTPN11 NF1	3.55e-04	125	142	5	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	MYC IDH1 KMT2C PTPN11 NF1	3.55e-04	125	142	5	C1879321
Disease	Malignant Glioma	ATRX IDH1 NF1 BRCA2	3.68e-04	70	142	4	C0555198
Disease	mixed gliomas	ATRX IDH1 NF1 BRCA2	3.68e-04	70	142	4	C0259783
Disease	Ischemic stroke, von Willebrand factor measurement	VWF HECTD4 FGB	4.03e-04	30	142	3	EFO_0004629, HP_0002140
Disease	Malignant neoplasm of urinary bladder	MYC MAGEA9 BPTF KMT2C BRCA2	6.15e-04	141	142	5	C0005684
Disease	Noonan syndrome (is_implicated_in)	RASA2 PTPN11	6.32e-04	8	142	2	DOID:3490 (is_implicated_in)
Disease	non-high density lipoprotein cholesterol measurement	GGNBP2 BEND5 R3HDM2 BCAS1 BPTF CSE1L BRCA2 RABEP1 ZPR1 FGB RAI1	6.93e-04	713	142	11	EFO_0005689
Disease	Giant Cell Glioblastoma	MYC IDH1 NF1 TP53BP1	7.36e-04	84	142	4	C0334588
Disease	lung adenocarcinoma (is_marker_for)	ATRX IDH1 KMT2C BTK	7.70e-04	85	142	4	DOID:3910 (is_marker_for)
Disease	cysteine measurement	NAV3 SENP6	8.10e-04	9	142	2	EFO_0021000
Disease	Glioma	IDH1 BRCA2	8.10e-04	9	142	2	cv:C0017638
Disease	cataract (implicated_via_orthology)	INTS1 NR3C1 BRCA2	8.14e-04	38	142	3	DOID:83 (implicated_via_orthology)
Disease	Prostatic Neoplasms	MYC CUL3 TBC1D2 BCAS1 IDH1 NR3C1 KMT2C BRCA2 SENP6 MGA	8.27e-04	616	142	10	C0033578
Disease	Malignant neoplasm of prostate	MYC CUL3 TBC1D2 BCAS1 IDH1 NR3C1 KMT2C BRCA2 SENP6 MGA	8.27e-04	616	142	10	C0376358
Disease	Glioma	ATRX IDH1 NF1 BRCA2	8.40e-04	87	142	4	C0017638
Disease	comparative body size at age 10, self-reported	GGNBP2 RASA2 R3HDM2 FARP2 MAGI2 NF1 PRKG2 PPP6R3	1.01e-03	420	142	8	EFO_0009819
Disease	urea measurement	SHROOM3 TGM3	1.01e-03	10	142	2	EFO_0011005
Disease	smoking cessation	TOM1L2 CUL3 TOM1 DEF8 MCM2 ITPR3 NFAT5	1.03e-03	325	142	7	EFO_0004319
Disease	Neurodevelopmental Disorders	CUL3 KMT2C PTPN11 KMT5B	1.08e-03	93	142	4	C1535926
Disease	Childhood Medulloblastoma	MPL MYC BRCA2	1.17e-03	43	142	3	C0278510
Disease	Melanotic medulloblastoma	MPL MYC BRCA2	1.17e-03	43	142	3	C1275668
Disease	Medullomyoblastoma	MPL MYC BRCA2	1.17e-03	43	142	3	C0205833
Disease	Desmoplastic Medulloblastoma	MPL MYC BRCA2	1.17e-03	43	142	3	C0751291
Disease	Adult Medulloblastoma	MPL MYC BRCA2	1.17e-03	43	142	3	C0278876
Disease	risk-taking behaviour	CUL3 MAP2 BCAS1 ERLEC1 MAGI2 BPTF NF1 KCNJ3 RBM19 DGKI NFAT5	1.21e-03	764	142	11	EFO_0008579
Disease	follistatin measurement	R3HDM2 TP53BP1	1.23e-03	11	142	2	EFO_0010614
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	R3HDM2 BPTF BRCA2 ZPR1 TP53BP1	1.28e-03	166	142	5	EFO_0004530, EFO_0004611
Disease	fibrinogen measurement, tissue plasminogen activator measurement	HECTD4 FARP2 FGB	1.34e-03	45	142	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	HECTD4 FARP2 FGB	1.34e-03	45	142	3	EFO_0004623, EFO_0004792
Disease	Adenoid Cystic Carcinoma	ATRX MAGI2 KMT2C MGA	1.41e-03	100	142	4	C0010606
Disease	apolipoprotein B measurement	ARHGEF19 R3HDM2 PPIB FARP2 BPTF PTPN11 NF1 BRCA2 ZPR1 FGB	1.43e-03	663	142	10	EFO_0004615
Disease	Hematologic Neoplasms	MPL IDH1	1.47e-03	12	142	2	C0376545
Disease	Neurobehavioral Manifestations	MAGI2 RAI1	1.47e-03	12	142	2	C0525041
Disease	Neuroblastoma	MYC ATRX PTPN11	1.52e-03	47	142	3	C0027819
Disease	vitamin D measurement, COVID-19	BCAS1 DPP9 ZPR1	1.71e-03	49	142	3	EFO_0004631, MONDO_0100096
Disease	Medulloblastoma	MPL MYC BRCA2	1.81e-03	50	142	3	C0025149
Disease	gallstones	SHROOM3 HID1 FARP2 NFAT5	1.87e-03	108	142	4	EFO_0004210
Disease	retinal drusen	GADD45B AVEN VWF	1.92e-03	51	142	3	EFO_1001155
Disease	Psychosis, Brief Reactive	DRD5 NR3C1	2.01e-03	14	142	2	C0033958
Disease	Schizophreniform Disorders	DRD5 NR3C1	2.01e-03	14	142	2	C0036358
Disease	heart failure	AVEN HECTD4 BPTF ZNF638 NFAT5	2.06e-03	185	142	5	EFO_0003144
Disease	Ischemic stroke, tissue plasminogen activator measurement	HECTD4 FGB	2.32e-03	15	142	2	EFO_0004791, HP_0002140
Disease	RASopathy	PTPN11 NF1	2.32e-03	15	142	2	cv:C5555857
Disease	leukemia	BLM PTPN11 NF1	2.38e-03	55	142	3	C0023418
Disease	Chronic Lymphocytic Leukemia	MYC FARP2 BTK	2.38e-03	55	142	3	C0023434
Disease	triglycerides in LDL measurement	BPTF ZPR1 TP53BP1	2.51e-03	56	142	3	EFO_0022320
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	HECTD4 FARP2 FGB	2.51e-03	56	142	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	HECTD4 FGB	2.64e-03	16	142	2	EFO_0004792, HP_0002140
Disease	idiopathic scoliosis (implicated_via_orthology)	PTPN11 DNAAF1	2.64e-03	16	142	2	DOID:0060250 (implicated_via_orthology)
Disease	glycoprotein measurement	R3HDM2 ZPR1 FGB TP53BP1	2.66e-03	119	142	4	EFO_0004555
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 R3HDM2 ZPR1 TP53BP1	2.83e-03	121	142	4	EFO_0008595, EFO_0020943
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	SHROOM3 R3HDM2 ZPR1 NFAT5 TP53BP1	2.88e-03	200	142	5	EFO_0004611, EFO_0020945
Disease	metabolic syndrome	HECTD4 BPTF ZPR1 NFAT5 WDR48	2.88e-03	200	142	5	EFO_0000195
Disease	MAJOR AFFECTIVE DISORDER 2	TOM1 MAGI2	2.98e-03	17	142	2	C1839839
Disease	factor XI measurement, Ischemic stroke	HECTD4 FGB	2.98e-03	17	142	2	EFO_0004694, HP_0002140
Disease	triglycerides in small VLDL measurement	BPTF ZPR1 TP53BP1	3.20e-03	61	142	3	EFO_0022145
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	R3HDM2 BPTF ZPR1 TP53BP1 RAI1	3.27e-03	206	142	5	EFO_0004612, EFO_0020947
Disease	triglycerides in small HDL measurement	BPTF ZPR1 TP53BP1	3.35e-03	62	142	3	EFO_0022158
Disease	phospholipids in large VLDL measurement	BPTF ZPR1 TP53BP1	3.35e-03	62	142	3	EFO_0022169
Disease	triglycerides in medium LDL measurement	BPTF ZPR1 TP53BP1	3.35e-03	62	142	3	EFO_0022322
Disease	triglycerides to total lipids in very large HDL percentage	BPTF ZPR1 TP53BP1	3.35e-03	62	142	3	EFO_0022339
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 R3HDM2 ZPR1 TP53BP1	3.36e-03	127	142	4	EFO_0008595, EFO_0020947
Disease	Noonan-Like Syndrome With Loose Anagen Hair	RASA2 PTPN11	3.73e-03	19	142	2	C3501846
Disease	Noonan syndrome-like disorder with loose anagen hair	RASA2 PTPN11	3.73e-03	19	142	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	RASA2 PTPN11	3.73e-03	19	142	2	C1275081
Disease	unipolar depression, response to bupropion, mood disorder	CUL3 NAV3	3.73e-03	19	142	2	EFO_0003761, EFO_0004247, EFO_0006326
Disease	Costello syndrome (disorder)	RASA2 PTPN11	3.73e-03	19	142	2	C0587248
Disease	Juvenile Myelomonocytic Leukemia	PTPN11 NF1	3.73e-03	19	142	2	C0349639
Disease	factor VIII measurement, Ischemic stroke	VWF HECTD4	3.73e-03	19	142	2	EFO_0004630, HP_0002140
Disease	triglycerides in small LDL measurement	BPTF ZPR1 TP53BP1	3.83e-03	65	142	3	EFO_0022323
Disease	Adenocarcinoma of prostate	MYC BRCA2	4.13e-03	20	142	2	C0007112
Disease	squamous cell carcinoma	DEF8 TGM3 BRCA2	4.17e-03	67	142	3	EFO_0000707
Disease	venous thromboembolism, fibrinogen measurement	VWF HECTD4 FGB	4.17e-03	67	142	3	EFO_0004286, EFO_0004623
Disease	aspartate aminotransferase measurement	BDP1 ARHGEF19 SHROOM3 THSD7A ZC3H8 HECTD4 R3HDM2 PTPN11 NF1 ZPR1 ZNF638	4.42e-03	904	142	11	EFO_0004736
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	SHROOM3 PTPN11 ZPR1 NFAT5 TP53BP1	4.49e-03	222	142	5	EFO_0008317, EFO_0020943
Disease	Prostate cancer, familial	BCAS1 BRCA2 KDM2A	4.53e-03	69	142	3	C2931456
Disease	bone density, lean body mass	TOM1L2 PPP6R3	4.55e-03	21	142	2	EFO_0003923, EFO_0004995
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	VWF CKAP5	4.55e-03	21	142	2	EFO_0004286, EFO_0004792
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	SHROOM3 R3HDM2 BPTF ZPR1 TP53BP1	4.66e-03	224	142	5	EFO_0004530, EFO_0008317

Protein segments in the cluster

Peptide	Gene	Start	Entry
AIDLEKVKSECLEPE	BEND5	251	Q7L4P6
VESPVICKILDTADE	ERLEC1	461	Q96DZ1
LEECSKIEVKEESPQ	EPB41	176	P11171
EKFCEDIGVEPENVV	DCUN1D4	126	Q92564
DVLLCEQEVVADETP	ABCF1	361	Q8NE71
EVLRTKGPCVVEEND	BDP1	266	A6H8Y1
EILKVGELPSETCND	ELMO1	426	Q92556
SKETEPDCLEVKELT	GJD2	161	Q9UKL4
IDVEKITCVETVVPE	BTK	56	Q06187
PKDLETTICLIDVDT	BPIFB4	511	P59827
EEPEEITCLEKGLAE	AKAP12	571	Q02952
DKVVDKIDVCPENAE	COMP	511	P49747
EICRKFETEEEKVLP	CCDC65	351	Q8IXS2
TREQICEVEEGDKPD	ALDH1A3	56	P47895
KPQDEICDAFEEVVL	CCNI2	141	Q6ZMN8
QESPTVELKDKLECE	CEP57	386	Q86XR8
DIIPLESCQCEEILE	ADCY10	1051	Q96PN6
DVEVLEPLKCELVSG	BPTF	1451	Q12830
EKFCEDIGVEPENII	DCUN1D5	71	Q9BTE7
VKGSEICLEEELPDE	CFAP251	1111	Q8TBY9
ICLEEELPDEITAEI	CFAP251	1116	Q8TBY9
PSKEEIEKECEDTSL	R3HDM2	36	Q9Y2K5
PLICTKEEVEEVLDS	RAI1	896	Q7Z5J4
EEEEESLPGCTLFIK	RBM19	721	Q9Y4C8
LELCGNEVVEVPEIK	PZP	886	P20742
CEIDPIKLKEGDNVE	RASA2	436	Q15283
EEEIKIPVVCALTQE	RABEP1	341	Q15276
ELDCEGEISLDKITP	DRD5	456	P21918
CEKSEPLLIAEDSAI	PCDHGA11	786	Q9Y5H2
DCVSGLSVPEVLEED	ITPR3	2431	Q14573
IVAQDIKEISGLEPC	LRRC9	61	Q6ZRR7
DLVDSCKPGDEIELT	MCM2	401	P49736
EICVAKISEPEADVE	LTN1	496	O94822
EDKEVISEGEDCPQV	ARHGEF19	706	Q8IW93
CAVEPLKAELAELEQ	TRAF3IP1	641	Q8TDR0
CTAEEEEAEVRQPKG	LRCH3	381	Q96II8
PDIENEDFIKDCVRI	GLIPR1	26	P48060
EEIKLEKAETESCPG	KMT2C	3716	Q8NEZ4
LAIIAIEGDCAPEEK	MAGEA2	206	P43356
GVILTKDNCAPEEVI	MAGEA9	206	P43362
EVVDILKDCPIGSET	MAGI2	661	Q86UL8
ITKDEPVCAIKNEEE	MAP9	101	Q49MG5
IVKSLSSEPCDLEEI	NLRC4	811	Q9NPP4
CPEGVTVKQEETDEE	MGA	396	Q8IWI9
GEQCSVEPDLISKVL	INTS1	1531	Q8N201
DDDDVIFCSEILPTK	ZBTB33	191	Q86T24
VCDIPTPLQTADEKE	GGNBP2	386	Q9H3C7
VKVLRDIEPGDEVTC	KMT5C	201	Q86Y97
DDILDISKCELSEIP	LRSAM1	31	Q6UWE0
IKELEASEELDTICP	GLRX3	216	O76003
DVLEKATQCVPKEEI	GRPEL1	116	Q9HAV7
EVEEPSACADTKILI	DST	3161	Q03001
DPEKLASCDIVVDVG	MYG1	81	Q9HB07
VKALRDIEPGEEISC	KMT5B	291	Q4FZB7
FEELCAELLQKIEVP	HSPH1	306	Q92598
IIPLVVKFCNVDDDE	CAND1	256	Q86VP6
CNIPVVSGKECEEII	FGB	231	P02675
EILDDNDCAPEVIVT	PCDHGB2	336	Q9Y5G2
ISSEERKLPCVEEVV	MYF6	226	P23409
AKQCLEEISGEDPET	NAV3	666	Q8IVL0
VDTIEQETIKPLDDC	CRLF3	81	Q8IUI8
EDFIELCTPGVIKQE	NR3C1	281	P04150
EKGVDCDIDVPKTIQ	PTPN11	481	Q06124
GPEITKEEEACQELL	HECTD4	796	Q9Y4D8
CISEESEPEDQKLTL	GRPEL2	126	Q8TAA5
PCKEVDIEGTTVIEV	NFAT5	356	O94916
PEDKLTKIIDCLEVE	PRKG2	291	Q13237
ETIEPVNILDVKDDC	NUTM1	896	Q86Y26
NLTCPEEEDTVKVVG	PRG2	86	P13727
EIVEPELSIEVCEEK	CKAP5	581	Q14008
CPITTKLVLDEDEET	ATRX	1531	P46100
VKCATITPDEKRVEE	IDH1	71	O75874
KLIKCDEIQVDSEEP	KLHL12	181	Q53G59
KCVPTGIEDEDALIA	KDM2A	476	Q9Y2K7
EEAELHSTEKVPCIE	BLM	276	P54132
VAVTFTKCEEEPLDL	BRCA2	2466	P51587
LEKICEEVIVPESTN	DNAH3	3591	Q8TD57
DGEVVQEEEVCAKPS	AVEN	316	Q9NQS1
VVCDGTDLTPKIQEL	DGKI	586	O75912
EDEFKCPIKEEIALT	DPP9	476	Q86TI2
PDSVVLCLLAIDEEE	GADD45B	51	O75293
CLDKSTEEPIVKVVE	CUL3	251	Q13618
DTLEKSELTVPCDIV	CCDC73	691	Q6ZRK6
VKEIESCKEDVLDPE	DENND2C	121	Q68D51
EECKQVILELPEQSE	DEF8	151	Q6ZN54
EEINDPKEICVGSSD	DNAAF1	41	Q8NEP3
IQDTELPKAEECDTI	EDARADD	46	Q8WWZ3
GVESILEPCDEIEQK	FAM102B	246	Q5T8I3
LCPEDKDVVENGLIA	FHIP2A	506	Q5W0V3
EIFDIEPKCDGQVLL	FARP2	56	O94887
FEDSEIREKCLVPQV	GPR22	416	Q99680
VCESPVEIIKSKEVE	BCAS1	396	O75363
EKFVDDEKILVEPAC	SDS	256	P20132
SILEEQLDEETPKVC	SACS	3976	Q9NZJ4
VLTEATPKEKECEEL	PRR14L	261	Q5THK1
SLDKLVSIPDEIFCE	MTERF3	386	Q96E29
VSIPDEIFCEEIAKA	MTERF3	391	Q96E29
PLCKEEEGEETAQVL	MINDY2	216	Q8NBR6
KEILKEADTDVQVCP	TRMT1L	226	Q7Z2T5
IQKDKDIPAEDIICE	THSD7A	161	Q9UPZ6
KIPVLVSCEDDLSDD	TCAF1	201	Q9Y4C2
QGRPVVICDKEDTET	GFPT1	631	Q06210
EKEVPEDSLEECAIT	NBPF7P	216	P0C2Y1
EKEVPEDSLEECAIT	NBPF15	196	Q8N660
EKEVPEDSLEECAIT	NBPF19	196	A0A087WUL8
TCQDIEIKPLTLEEG	TDRD12	46	Q587J7
ICDPDDETFIKNIII	MYC	116	P01106
PQVEKICIDKGLTDE	HID1	706	Q8IV36
KFVECTEQLELLPGE	SMG1	1241	Q96Q15
EAVTVPVCEDQLKEI	SMG1	2731	Q96Q15
DVIIADCGKIEVEKP	PPIB	196	P23284
EEVEALISELCKPNE	SHROOM3	1816	Q8TF72
ENPEELKVIDCVVGL	WHAMM	436	Q8TF30
EPENEKILDILGETC	SAFB	211	Q15424
CKVPDESEVVVERDI	TGM3	576	Q08188
EAELEVVPIIAKCLE	TRIP10	236	Q15642
SVVTEDDCEILKIPA	CNBD1	281	Q8NA66
EEILCEFVQKDELKP	NCAPD2	736	Q15021
PCKIIDLEAVKVEEE	CLCA2	766	Q9UQC9
VDKCTEVLEGNPTVL	ZBTB43	116	O43298
AADIVESLGKPECEE	UBA6	421	A0AVT1
PVKCEGVKVDTEDSL	ZNF513	11	Q8N8E2
TEICEEAEKPLIISE	ZNF35	126	P13682
LKSETCSVEIPELEF	ZPR1	326	O75312
IVEDEPNKICEADRV	CSE1L	76	P55060
EEKIELLCQDQVLDP	WDR48	636	Q8TAF3
KILDELLQTCVDPED	VWF	1181	P04275
NIPIDTCREKEDLVD	RNF34	131	Q969K3
EVKVEAIPNCKSEEE	SLC1A4	491	P43007
ICDIINETEEGPKDA	TOM1	36	O60784
EPESIEGKVKNDICE	ZNF609	931	O15014
EIEPRLETAEKGCQT	ZNF646	1181	O15015
LCPEIIQDISKDVVD	NF1	276	P21359
EKVPIDIIVNCDDSK	SENP6	281	Q9GZR1
ERKVTEETEEPIVEC	TP53BP1	1266	Q12888
VSDTCEEVEPSLLEI	MPL	556	P40238
IQDEIAVKLSVEIPC	MAP2	1161	P11137
EPVIKEDKICAGDTQ	PRSS48	196	Q7RTY5
ETEKRCFIEEIPDET	TMED4	36	Q7Z7H5
VKEVLAEEECPALGT	ZNF316	86	A6NFI3
VIAEGKAEDVKPEEC	TSPYL6	141	Q8N831
ICDIINETEEGPKDA	TOM1L2	36	Q6ZVM7
TALEDIKPGEEICIS	SMYD5	336	Q6GMV2
AECLEDLVSFIIEEP	PPP6R3	51	Q5H9R7
CGDSIKPEETEQEVA	TOE1	371	Q96GM8
TELPEDGCTEEDVRK	ZNF638	681	Q14966
GQEEAELEEFLCPVK	TBC1D2	171	Q9BYX2
CEIIEISEDSPVNID	ZBTB6	161	Q15916
ETQEEKIKLECEQIP	ZC3H8	36	Q8N5P1
NKVTDPEVKEIIEGC	WNK3	371	Q9BYP7
VPATLFEICKLSEDE	GEMIN4	786	P57678
VECLDGLDDITTKLP	KCNJ3	386	P48549