Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Zfx_Zfy_act	ZNF711 ZFX ZFY	6.22e-08	3	75	3	PF04704
Domain	Transcrp_activ_Zfx/Zfy-dom	ZNF711 ZFX ZFY	6.22e-08	3	75	3	IPR006794
Domain	Znf_C2H2-like	ZNF711 ZNF462 ZNF610 ZNF775 RNF166 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	5.10e-07	796	75	15	IPR015880
Domain	zf-C2H2	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	5.67e-07	693	75	14	PF00096
Domain	Znf_C2H2	ZNF711 ZNF462 ZNF610 ZNF775 RNF166 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	5.88e-07	805	75	15	IPR007087
Domain	ZnF_C2H2	ZNF711 ZNF462 ZNF610 ZNF775 RNF166 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	6.17e-07	808	75	15	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	2.13e-06	775	75	14	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	2.19e-06	777	75	14	PS00028
Domain	-	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	2.74e-06	679	75	13	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	3.48e-06	694	75	13	IPR013087
Domain	KRAB	ZNF610 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519	5.82e-04	358	75	7	PS50805
Domain	KRAB	ZNF610 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519	5.82e-04	358	75	7	PF01352
Domain	KRAB	ZNF610 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519	6.95e-04	369	75	7	SM00349
Domain	KRAB	ZNF610 ZNF234 ZNF684 ZNF43 ZNF552 ZNF350 ZNF519	7.07e-04	370	75	7	IPR001909
Pubmed	Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.	ZNF711 ZFX ZFY	1.04e-08	3	77	3	32406922
Pubmed	Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.	ZFX ZFY	4.84e-06	2	77	2	12716983
Pubmed	Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.	ZFX ZFY	4.84e-06	2	77	2	9126493
Pubmed	Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.	ZFX ZFY	4.84e-06	2	77	2	19329779
Pubmed	Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.	ZFX ZFY	4.84e-06	2	77	2	1970799
Pubmed	Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.	ZFX ZFY	4.84e-06	2	77	2	8487630
Pubmed	Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.	ZFX ZFY	4.84e-06	2	77	2	1691708
Pubmed	The structure of the Zfx gene on the mouse X chromosome.	ZFX ZFY	4.84e-06	2	77	2	8188262
Pubmed	Comparison of human ZFY and ZFX transcripts.	ZFX ZFY	4.84e-06	2	77	2	2308929
Pubmed	Mapping the human ZFX locus to Xp21.3 by in situ hybridization.	ZFX ZFY	4.84e-06	2	77	2	2497060
Pubmed	RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.	ZFX ZFY	4.84e-06	2	77	2	28251288
Pubmed	Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.	ZFX ZFY	4.84e-06	2	77	2	2041734
Pubmed	Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.	ZFX ZFY	4.84e-06	2	77	2	8318216
Pubmed	Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.	ZFX ZFY	4.84e-06	2	77	2	2105457
Pubmed	Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.	ZFX ZFY	4.84e-06	2	77	2	34324278
Pubmed	Zfx mutation results in small animal size and reduced germ cell number in male and female mice.	ZFX ZFY	4.84e-06	2	77	2	9187153
Pubmed	[Expression of Zfx in mouse testicular spermatogenic cells].	ZFX ZFY	4.84e-06	2	77	2	38602753
Pubmed	Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.	ZFX ZFY	4.84e-06	2	77	2	2265557
Pubmed	Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.	ZFX ZFY	1.45e-05	3	77	2	2480529
Pubmed	Genetic dissection of mammalian fertility pathways.	ZFX ZFY	1.45e-05	3	77	2	12479614
Pubmed	Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.	ZFX ZFY	1.45e-05	3	77	2	9060403
Pubmed	Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.	ZFX ZFY	1.45e-05	3	77	2	38310188
Pubmed	Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs.	SIRT6 TET3	1.45e-05	3	77	2	30987683
Pubmed	YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.	ZFX ZFY	1.45e-05	3	77	2	8406471
Pubmed	X chromosome genes and premature ovarian failure.	ZFX ZFY	1.45e-05	3	77	2	11299520
Pubmed	ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.	ZFX ZFY	2.89e-05	4	77	2	24485662
Pubmed	Zfx controls the self-renewal of embryonic and hematopoietic stem cells.	ZFX ZFY	2.89e-05	4	77	2	17448993
Pubmed	The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).	ZFX ZFY	4.82e-05	5	77	2	9244432
Pubmed	Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.	ZFX ZFY	4.82e-05	5	77	2	25164012
Pubmed	Chromosome mapping and expression of a putative testis-determining gene in mouse.	ZFX ZFY	4.82e-05	5	77	2	2563174
Pubmed	MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.	ZFX ZFY	4.82e-05	5	77	2	9721210
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	ZFX ZFY	4.82e-05	5	77	2	7681608
Pubmed	Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.	ZFX ZFY	7.22e-05	6	77	2	7821804
Pubmed	Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.	ZNF462 TRIP11 CDK6	7.68e-05	37	77	3	19266077
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	ZFX ZFY	1.01e-04	7	77	2	8460399
Pubmed	Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.	ZFX ZFY	1.01e-04	7	77	2	8378320
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	ZFX ZFY	1.01e-04	7	77	2	7928394
Pubmed	The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.	ZFX ZFY	1.01e-04	7	77	2	9588208
Pubmed	PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.	TTC7A EFR3A	1.01e-04	7	77	2	23229899
Pubmed	Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.	ZFX ZFY	1.01e-04	7	77	2	9196009
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	ZFX ZFY	1.34e-04	8	77	2	2034279
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	ZFX ZFY	1.34e-04	8	77	2	1974879
Pubmed	Diverse alternative back-splicing and alternative splicing landscape of circular RNAs.	MED13L ZFX	1.34e-04	8	77	2	27365365
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	ZFX ZFY	1.34e-04	8	77	2	1675191
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TTC7A ZNF462 AP2A2 SETBP1 MED13L	1.47e-04	225	77	5	12168954
Pubmed	Identification of G protein-coupled receptor genes from the human genome sequence.	HCAR2 GPRC6A ADGRF3	1.48e-04	46	77	3	12044878
Pubmed	exma: an X-linked insertional mutation that disrupts forebrain and eye development.	ZFX ZFY	1.72e-04	9	77	2	11956759
Pubmed	Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.	ZFX ZFY	1.72e-04	9	77	2	7590750
Pubmed	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.	ZFX ZFY	1.72e-04	9	77	2	7874112
Pubmed	The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.	ZFX ZFY	1.72e-04	9	77	2	9300697
Pubmed	Genetic control of retinal ganglion cell projections.	TYRP1 LYST	1.72e-04	9	77	2	102659
Pubmed	Praja1, a novel gene encoding a RING-H2 motif in mouse development.	ZFX ZFY	1.72e-04	9	77	2	9393880
Pubmed	The fine structure of melanogenesis in coat color mutants of the mouse.	TYRP1 LYST	1.72e-04	9	77	2	4634048
Pubmed	Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen.	TTC7A LYST	2.15e-04	10	77	2	9328433
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	ZFX ZFY	2.15e-04	10	77	2	2055107
Pubmed	Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.	ZFX ZFY	2.15e-04	10	77	2	1973380
Pubmed	Characterization of a murine gene expressed from the inactive X chromosome.	ZFX ZFY	2.63e-04	11	77	2	2034278
Pubmed	Zinc finger protein genes in the mouse genome.	ZFX ZFY	3.15e-04	12	77	2	1797234
Pubmed	The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction.	ZFX ZFY	3.15e-04	12	77	2	1916827
Pubmed	The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.	ZFX ZFY	3.71e-04	13	77	2	7805729
Pubmed	Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.	ZFX ZFY	3.71e-04	13	77	2	2721933
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	ZFX ZFY	3.71e-04	13	77	2	1740345
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	ZFX ZFY	3.71e-04	13	77	2	1772416
Pubmed	Network-Based Combinatorial CRISPR-Cas9 Screens Identify Synergistic Modules in Human Cells.	IL10RB DCC IL18R1	3.77e-04	63	77	3	30762338
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	ZFX ZFY	4.33e-04	14	77	2	8432533
Pubmed	Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population.	IL10RB IL18R1	4.33e-04	14	77	2	18715339
Pubmed	Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.	TYRP1 LYST	4.99e-04	15	77	2	18715234
Pubmed	Molecular phylogenetics and the origins of placental mammals.	ZFX ZFY	4.99e-04	15	77	2	11214319
Pubmed	Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.	ZFX ZFY	4.99e-04	15	77	2	11353388
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	ZFX ZFY	4.99e-04	15	77	2	14762062
Pubmed	Platelet storage pool deficiency in mouse pigment mutations associated with seven distinct genetic loci.	TYRP1 LYST	4.99e-04	15	77	2	6696991
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTK2B WWC2 TRPM7 NHS TRIP11 LYST HDAC7 RUSC2	6.37e-04	861	77	8	36931259
Pubmed	Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.	ZFX ZFY	6.44e-04	17	77	2	19571810
Pubmed	HDAC family: What are the cancer relevant targets?	SIRT6 HDAC7	7.23e-04	18	77	2	18824292
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	ZNF462 WWC2 TRIP11 CDK6	9.97e-04	198	77	4	20881960
Pubmed	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	ZNF462 TRIP11 CDK6	1.10e-03	91	77	3	20546612
Pubmed	Identification of ten loci associated with height highlights new biological pathways in human growth.	TRIP11 CDK6	1.19e-03	23	77	2	18391950
Pubmed	Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.	ZFX ZFY	1.52e-03	26	77	2	10920247
Pubmed	Gene knockouts that cause female infertility: search for novel contraceptive targets.	ZFX ZFY	1.76e-03	28	77	2	15970507
Pubmed	Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.	PTK2B SIRT6	1.89e-03	29	77	2	24105743
Pubmed	Functional proteomics mapping of a human signaling pathway.	RNF123 AP2A2 ZNF451 ZNF350 ASCC3 SKIL	2.01e-03	591	77	6	15231748
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF462 ZNF610 ZNF775 ZNF43 ZNF451 SKIL ZNF710	2.09e-03	808	77	7	20412781
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF711 ZNF462 ZNF610 ZNF775 ZNF234 ZNF684 ZNF43 ZNF451 ZNF552 ZNF350 ZNF519 ZFX ZFY ZNF710	3.37e-08	718	57	14	28
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHPT1 TRPM7 PODN ASCC3 TRIP11 LYST	5.73e-07	176	76	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTC7A PTK2B TEP1 TNFRSF21 ZNF710	1.02e-05	168	76	5	00cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTC7A PTK2B TEP1 TNFRSF21 ZNF710	1.05e-05	169	76	5	90c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TYRP1 ADAMTS6 SETBP1 NHS DCC	1.71e-05	187	76	5	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TRPM7 ETNK1 IL18R1 LYST CDK6	1.89e-05	191	76	5	9454f642c3621370fa23640b631301346b300950
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PTK2B CHPT1 SETBP1 SKIL LYST	2.04e-05	194	76	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TTC7A LYST TET3 WDR49 ZNF710	2.25e-05	198	76	5	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF462 ZNF234 CDK15 ZNF43 TNFRSF21	2.36e-05	200	76	5	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF462 ZNF234 CDK15 ZNF43 TNFRSF21	2.36e-05	200	76	5	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	RNF123 AP2A2 ETNK1 GREB1 MED13L RFNG SKIL ZFX	2.36e-07	190	76	8	7405_DN
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	AP2A2 ZNF350 GREB1 TNFRSF21 LYST HDAC7 ZFX ZNF710	2.66e-07	193	76	8	3614_DN
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A	AP2A2 CTC1 ZNF552 RFNG SKIL TRIP11 RUSC2	4.03e-06	195	76	7	1156_UP
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	TYRP1 AP2A2 HAP1 PPFIBP2 GREB1 UBOX5 HDAC7	4.60e-06	199	76	7	3640_DN
Drug	Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A	ZNF711 AP2A2 GREB1 UBOX5 TRIP11 INO80D ZFX	4.76e-06	200	76	7	6005_DN
Drug	Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	PTK2B AP2A2 HAP1 SETBP1 UBOX5 TRIP11 CDK6	4.76e-06	200	76	7	4837_UP
Drug	Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	AP2A2 PPFIBP2 ZNF350 GREB1 TEP1 RUSC2	4.45e-05	192	76	6	3318_DN
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	ZNF43 ZNF350 GREB1 SKIL TRIP11 LYST	4.58e-05	193	76	6	3258_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	WWC2 ETNK1 MED13L UBOX5 ZFX ZNF710	4.86e-05	195	76	6	6918_UP
Drug	Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; MCF7; HT_HG-U133A	TYRP1 HAP1 TEP1 UBOX5 INO80D HDAC7	4.86e-05	195	76	6	3376_DN
Drug	Sulfaphenazole [526-08-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	MGAT4B AP2A2 ZNF552 ZNF350 DCC UBOX5	5.00e-05	196	76	6	1673_UP
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A	AP2A2 PPFIBP2 GREB1 SKIL TEP1 UBOX5	5.00e-05	196	76	6	3302_DN
Drug	Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT_HG-U133A	TYRP1 GYG2 TEP1 TRIP11 ZNF710 RUSC2	5.00e-05	196	76	6	4125_DN
Drug	Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A	AP2A2 GYG2 RFNG UBOX5 LYST HDAC7	5.00e-05	196	76	6	3342_DN
Drug	Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A	HAP1 ZNF43 PPFIBP2 GYG2 SKIL UBOX5	5.14e-05	197	76	6	3319_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	AP2A2 GYG2 SKIL TEP1 INO80D ZNF710	5.14e-05	197	76	6	5025_DN
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; PC3; HG-U133A	CTC1 ZNF43 GYG2 ETNK1 INO80D HDAC7	5.29e-05	198	76	6	1928_UP
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; PC3; HT_HG-U133A	ZNF350 SIRT6 TEP1 UBOX5 HDAC7 RUSC2	5.29e-05	198	76	6	4592_DN
Drug	Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; HL60; HT_HG-U133A	AP2A2 ZNF43 INO80D HDAC7 ZFX ZNF710	5.29e-05	198	76	6	2714_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	RNF123 AP2A2 HAP1 PPFIBP2 GYG2 UBOX5	5.44e-05	199	76	6	3638_DN
Drug	Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; PC3; HT_HG-U133A	ZNF711 AP2A2 TEP1 UBOX5 INO80D ZNF710	5.44e-05	199	76	6	6640_DN
Drug	Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PPFIBP2 TEP1 UBOX5 INO80D ZNF710 RUSC2	5.44e-05	199	76	6	5280_UP
Drug	Nifurtimox [23256-30-6]; Up 200; 14uM; MCF7; HT_HG-U133A	ZNF711 AP2A2 PPFIBP2 TEP1 HDAC7 RUSC2	5.59e-05	200	76	6	4953_UP
Drug	wortmannin; Up 200; 0.01uM; ssMCF7; HG-U133A	HAP1 DCC UBOX5 TRIP11 TNFRSF21 CDK6	5.59e-05	200	76	6	404_UP
Drug	dihomo-gamma-linolenylethanolamide	TTC7A PTK2B	1.09e-04	5	76	2	CID000002184
Disease	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	SETBP1 ETNK1	1.86e-05	3	74	2	C1292772
Disease	Autistic behavior	ZNF462 TET3	1.72e-04	8	74	2	C0856975
Disease	Mental Retardation, Psychosocial	SETBP1 ASCC3 MED13L DCC	4.20e-04	139	74	4	C0025363
Disease	Profound Mental Retardation	SETBP1 ASCC3 MED13L DCC	4.20e-04	139	74	4	C0020796
Disease	Mental deficiency	SETBP1 ASCC3 MED13L DCC	4.20e-04	139	74	4	C0917816
Disease	cutaneous melanoma, hair color	TYRP1 PPFIBP2 MED13L	5.15e-04	62	74	3	EFO_0000389, EFO_0003924
Disease	Intellectual Disability	ZNF462 SETBP1 ASCC3 MED13L DCC TET3	9.08e-04	447	74	6	C3714756
Disease	hair color	TYRP1 PLB1 RNF166 PPFIBP2 MED13L	1.12e-03	311	74	5	EFO_0003924
Disease	Infiltrating duct carcinoma of female breast	CDK15 TRPM7	1.26e-03	21	74	2	C3165106
Disease	suicidal ideation	SLC25A16 CFAP46	2.41e-03	29	74	2	EFO_0004320
Disease	Myeloid Leukemia, Chronic	SETBP1 ETNK1	2.41e-03	29	74	2	C0023473

Protein segments in the cluster

Peptide	Gene	Start	Entry
LAHQLLFVFHQLAKH	ADGRF3	866	Q8IZF5
LKAPHANRFIFSHDL	ADPGK	221	Q9BRR6
LCPHVLRHHQFLQHS	CTC1	481	Q2NKJ3
NHHHRLQLKAAPASS	ANKRD13C	56	Q8N6S4
QHNLRHHLRKPLAGV	CFAP46	396	Q8IYW2
LHSHRVVHRDLKPQN	CDK6	136	Q00534
NNAVRPVFAHLDHHK	EFR3A	251	Q14156
LPINNTHIHHRQKRS	ADAMTS6	231	Q9UKP5
SSPLIQFHLLHSKFH	AP2A2	516	O94973
QFHLLHSKFHLCSVP	AP2A2	521	O94973
PLDRVKVLLQAHNHH	SLC25A16	56	P16260
LTPAQLHHLLSHYQL	RASIP1	861	Q5U651
RLLHSPLFHSHLENL	RFNG	251	Q9Y644
EIFRLHFGLKQHHQT	ATP23	166	Q9Y6H3
HPLAFQGLKRLHTVH	PODN	351	Q7Z5L7
SLLIQNILHSRHHKP	DCC	96	P43146
VHFLHHNGKLFNITK	IL18R1	186	Q13478
QNQCPLFLKASLHHH	MED13L	2121	Q71F56
HSHLFFPLSLKNHDH	GREB1	1821	Q4ZG55
FHHLPHLLAKESSLQ	MGAT4B	116	Q9UQ53
RFLDLSQNHLHHCPL	LRRIQ4	306	A6NIV6
HPHHALNKISNRTAA	HCAR2	131	Q8TDS4
HFLRSHNLEGQHKAL	OR4X1	221	Q8NH49
NIANNPHLLSLHKFT	LRRC52	131	Q8N7C0
AIHVLHVNKFNPHCL	PPFIBP2	686	Q8ND30
HVNKFNPHCLHRRPA	PPFIBP2	691	Q8ND30
HFQHPSKLHLRVVTL	GRIN3A	506	Q8TCU5
QNLHLLPSDSHKLLH	GPRC6A	341	Q5T6X5
VFQPSLHTHKLLLQH	GYG2	171	O15488
FHHPKLSSLHRENFI	HYKK	161	A2RU49
HHQHVLHRDLKPQNL	CDK15	216	Q96Q40
HFHLLRHKPFAANGR	FNDC1	816	Q4ZHG4
APKLISQEALLHQHH	HAP1	296	P54257
HHRRLLTPAFHFNIL	CYP4F8	146	P98187
PSRHALRKFHITNHA	CARD19	96	Q96LW7
LKEFLGHPHHNTLLF	IL10RB	266	Q08334
KHRRPHLLHHFLTSF	LYST	181	Q99698
LPFTRHCFQHILLNH	INO80D	461	Q53TQ3
ARQLAKIHAIHAHNG	ETNK1	231	Q9HBU6
ALQRPQRLHHHLFLA	HDAC7	21	Q8WUI4
NSLHTPPLHRHNVFK	PTK2B	761	Q14289
IAPVLKLASHHNHFS	OR10K2	181	Q6IF99
HHFPKQLAKARALHS	RUSC2	701	Q8N2Y8
HPSLKARIDHFLLQH	UBOX5	321	O94941
IAHLNLRDHQLSFKH	TRMT5	206	Q32P41
PRQNLHKHFDINEHL	TNFRSF21	336	O75509
HLNPSLKHTLAQFHL	SKIL	81	P12757
LSALHNVLNKPFHHR	NHS	1091	Q6T4R5
NVLNKPFHHRHPLHV	NHS	1096	Q6T4R5
KSANFLQHLLHRHKF	RNF166	196	Q96A37
IHPNQKFHSQLARAL	PLB1	1001	Q6P1J6
LQPTKHDRHADLRIH	SIRT6	241	Q8N6T7
SPHTKAHLLLQAHLS	ASCC3	1886	Q8N3C0
LLTLPNIENHHLHLF	ASCC3	1961	Q8N3C0
HLHLNIFKTACHQAP	CHPT1	376	Q8WUD6
VFNQNPHLSRHRKIH	ZNF610	436	Q8N9Z0
FKKTQRPAHILNPHH	ZNF451	991	Q9Y4E5
HLATHQKIHNGERPF	ZNF684	201	Q5T5D7
PAVRSLHNLAHLFLN	TYRP1	371	P17643
QLRNLHAFLIPHTSK	WWC2	721	Q6AWC2
HLAQHQRIHTGEKPF	ZNF519	306	Q8TB69
FLHKIHTNHLPNGHI	RASGEF1A	391	Q8N9B8
QRLHIHKPAQHVQAL	TEP1	446	Q99973
TLAHIFHHFAPLLRK	RNF123	316	Q5XPI4
AFNQPSHLATHKRIH	ZNF723	321	P0DPD5
AHHVLHPDYQRLLKS	WDR49	316	Q8IV35
HLLKHLRTHLPGAQA	ZNF775	351	Q96BV0
LFKQPSHLQTHLLTH	ZNF710	331	Q8N1W2
TALQQHLHHKRSLFL	TET3	526	O43151
FRNLLSVGHHPFKHD	ZNF234	41	Q14588
LPHLAQHKIIHTRVN	ZNF43	186	P17038
HANHERLHTAIKFPA	ZNF350	166	Q9GZX5
LFNSKSHLLVHQRIH	ZNF552	276	Q9H707
NLFIGHFHTPKNQRH	TRIP11	1786	Q15643
HFHTPKNQRHEVLRL	TRIP11	1791	Q15643
RHLLAVHSKNFPHIC	ZFX	536	P17010
LLALLFSAQKHHQHA	TTC7A	571	Q9ULT0
RVHQQHKHSFCDNLP	ZNF462	616	Q96JM2
LNRHLLAVHSKNFPH	ZNF711	491	Q9Y462
GHRQKHLIVDNFLAH	SETBP1	916	Q9Y6X0
PLSKLNVLNNLHSHF	TRPM7	231	Q96QT4
KPHVSDHNRLLHLAR	THEG	291	Q9P2T0
NRHLLAVHSKNFPHI	ZFY	531	P08048