Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneuron migration

ZNF609 KIF26A GATA3 ULK1 ZMIZ1 ROBO3 RAPGEF2 MAPK8IP3

4.65e-07218668GO:0001764
GeneOntologyBiologicalProcessnegative regulation of developmental growth

MAP2 ATXN2 RTN4 ULK1 ULK2 RAI1

3.10e-06126666GO:0048640
GeneOntologyBiologicalProcesssomatic sensory system development

ULK1 ULK2

1.01e-052662GO:0160038
GeneOntologyBiologicalProcessnegative regulation of axonogenesis

MAP2 RTN4 ULK1 ULK2

4.64e-0562664GO:0050771
GeneOntologyBiologicalProcessregulation of neuron migration

ZNF609 KIF26A RAPGEF2 MAPK8IP3

4.64e-0562664GO:2001222
GeneOntologyBiologicalProcessregulation of cellular component size

FCHSD2 BAIAP2L1 MAP2 RTN4 LRRC8A ULK1 ULK2 HCK

6.25e-05426668GO:0032535
GeneOntologyBiologicalProcesspositive regulation of neuron migration

ZNF609 RAPGEF2 MAPK8IP3

6.84e-0525663GO:2001224
GeneOntologyBiologicalProcessregulation of protein localization to endoplasmic reticulum

RTN4 NACA

1.00e-045662GO:1905550
GeneOntologyBiologicalProcessdevelopmental growth

MAP2 ATXN2 RTN4 NACA GATA3 TNS2 ULK1 ZMIZ1 PPP1R13L ULK2 RAI1

1.36e-049116611GO:0048589
GeneOntologyBiologicalProcessneuron development

MAP2 NRL ATXN2 KIF26A RTN4 GATA3 PCARE ULK1 ZMIZ1 CTNND2 ROBO3 RAPGEF2 ULK2 MAPK8IP3

1.80e-0414636614GO:0048666
GeneOntologyBiologicalProcessneuron projection morphogenesis

MAP2 ATXN2 RTN4 GATA3 ULK1 CTNND2 ROBO3 RAPGEF2 ULK2 MAPK8IP3

2.19e-048026610GO:0048812
GeneOntologyBiologicalProcessnegative regulation of neurogenesis

MAP2 RTN4 ULK1 RAPGEF2 ULK2

2.32e-04173665GO:0050768
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

MAP2 ATXN2 RTN4 GATA3 ULK1 CTNND2 ROBO3 RAPGEF2 ULK2 MAPK8IP3

2.59e-048196610GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

MAP2 ATXN2 RTN4 GATA3 ULK1 CTNND2 ROBO3 RAPGEF2 ULK2 MAPK8IP3

2.78e-048266610GO:0048858
GeneOntologyBiologicalProcessnegative regulation of growth

MAP2 ATXN2 RTN4 ULK1 ULK2 RAI1

2.88e-04283666GO:0045926
GeneOntologyBiologicalProcessnegative regulation of nervous system development

MAP2 RTN4 ULK1 RAPGEF2 ULK2

3.08e-04184665GO:0051961
GeneOntologyBiologicalProcessregulation of developmental growth

MAP2 ATXN2 RTN4 NACA ULK1 ULK2 RAI1

3.88e-04421667GO:0048638
GeneOntologyBiologicalProcessgrowth

MAP2 ATXN2 KIF26A RTN4 NACA GATA3 TNS2 ULK1 ZMIZ1 PPP1R13L ULK2 RAI1

4.89e-0412356612GO:0040007
GeneOntologyBiologicalProcessvasculogenesis

AMOT RTN4 ZMIZ1 RAPGEF2

5.58e-04118664GO:0001570
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

MAP2 RTN4 GATA3 ULK1 CTNND2 ROBO3 RAPGEF2 ULK2 MAPK8IP3

6.02e-04748669GO:0048667
GeneOntologyBiologicalProcessregulation of extent of cell growth

MAP2 RTN4 ULK1 ULK2

6.33e-04122664GO:0061387
GeneOntologyBiologicalProcessnegative regulation of collateral sprouting

ULK1 ULK2

6.52e-0412662GO:0048671
GeneOntologyBiologicalProcessregulation of cell development

FOXN1 ZNF609 MAP2 RTN4 NACA GATA3 CD46 ULK1 ZMIZ1 RAPGEF2 ULK2

6.56e-0410956611GO:0060284
GeneOntologyBiologicalProcessregulation of neuron projection development

MAP2 KIF26A RTN4 GATA3 ULK1 ROBO3 RAPGEF2 ULK2

7.25e-04612668GO:0010975
GeneOntologyBiologicalProcessregulation of cell size

MAP2 RTN4 LRRC8A ULK1 ULK2

7.69e-04225665GO:0008361
GeneOntologyBiologicalProcessregulation of anatomical structure size

FCHSD2 BAIAP2L1 MAP2 RTN4 LRRC8A ULK1 ULK2 HCK

7.72e-04618668GO:0090066
GeneOntologyBiologicalProcessregulation of T cell differentiation

FOXN1 ZNF609 GATA3 CD46 ZMIZ1

7.84e-04226665GO:0045580
GeneOntologyBiologicalProcesspositive regulation of actin filament polymerization

FCHSD2 BAIAP2L1 HCK

8.95e-0459663GO:0030838
GeneOntologyBiologicalProcessnegative regulation of cell projection organization

MAP2 RTN4 ULK1 RAPGEF2 ULK2

8.99e-04233665GO:0031345
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

FOXN1 ZNF609 ATOH8 RTN4 GATA3 LRRC8A CD46 ZMIZ1 RAPGEF2 PPP1R13L MAPK8IP3

9.21e-0411416611GO:0045597
GeneOntologyBiologicalProcessaxon extension

MAP2 RTN4 ULK1 ULK2

9.24e-04135664GO:0048675
GeneOntologyCellularComponentanchoring junction

FCHSD2 BAIAP2L1 AMOT RTN4 LPP TNS2 CD46 CTNND2 RAPGEF2 TRIM29 HCK ZYX

4.80e-059766612GO:0070161
DomainSer/Thr_kinase_C

ULK1 ULK2

1.16e-052642IPR022708
DomainDUF3543

ULK1 ULK2

1.16e-052642PF12063
DomainSer/Thr_kin_STPK_Ulk-1/2

ULK1 ULK2

1.16e-052642IPR016237
DomainCLTH

RANBP10 RANBP9

1.72e-046642PF10607
DomainCRA

RANBP10 RANBP9

1.72e-046642SM00757
DomainCTLH/CRA

RANBP10 RANBP9

1.72e-046642IPR024964
DomainCRA_dom

RANBP10 RANBP9

1.72e-046642IPR013144
Domainzf-MIZ

ZMIZ2 ZMIZ1

2.40e-047642PF02891
DomainZF_SP_RING

ZMIZ2 ZMIZ1

2.40e-047642PS51044
DomainSH3_1

FCHSD2 BAIAP2L1 ARHGEF9 PPP1R13L HCK

2.46e-04164645PF00018
DomainZnf_MIZ

ZMIZ2 ZMIZ1

3.19e-048642IPR004181
DomainCTLH

RANBP10 RANBP9

4.10e-049642SM00668
DomainLisH

RANBP10 RANBP9

4.10e-049642PF08513
DomainSPAN-X_fam

SPANXD SPANXC

5.11e-0410642IPR010007
DomainSPAN-X

SPANXD SPANXC

5.11e-0410642PF07458
DomainCTLH_C

RANBP10 RANBP9

5.11e-0410642IPR006595
DomainCTLH

RANBP10 RANBP9

5.11e-0410642PS50897
DomainSH3

FCHSD2 BAIAP2L1 ARHGEF9 PPP1R13L HCK

8.65e-04216645SM00326
DomainSH3

FCHSD2 BAIAP2L1 ARHGEF9 PPP1R13L HCK

8.65e-04216645PS50002
DomainSH3_domain

FCHSD2 BAIAP2L1 ARHGEF9 PPP1R13L HCK

9.39e-04220645IPR001452
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMKK2 ULK1 ULK2

1.71e-0369643IPR020636
Domain-

LPP SCEL ZYX

1.78e-03706432.10.110.10
DomainZnf_LIM

LPP SCEL ZYX

1.86e-0371643IPR001781
DomainLIM_DOMAIN_1

LPP SCEL ZYX

1.86e-0371643PS00478
DomainLIM_DOMAIN_2

LPP SCEL ZYX

1.86e-0371643PS50023
DomainLIM

LPP SCEL ZYX

1.86e-0371643SM00132
DomainSH3_9

FCHSD2 BAIAP2L1 PPP1R13L

2.43e-0378643PF14604
DomainLisH

RANBP10 RANBP9

4.13e-0328642SM00667
DomainLisH

RANBP10 RANBP9

4.13e-0328642IPR006594
DomainLISH

RANBP10 RANBP9

4.13e-0328642PS50896
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF609 CAMKK2 KIF26A AMOT PLCH2 RNF44 RTN4 NACA LRRC8A BSN KDM6B RGP1 RAI1

2.42e-11529671314621295
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RANBP10 PCNX3 KIF26A ZMIZ2 POLR2A MED14 ULK1 KDM6B POM121C ULK2 PRRC2B RAI1 MAPK8IP3

1.62e-071105671335748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF469 ZNF609 POLR2A RANBP9 SCEL RAPGEF2 SRRM2 POM121C NCKAP5L PDHX AFF4 PRRC2B RAI1

1.81e-071116671331753913
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

FAM168A LPP CTNND2 BSN PPP1R13L NCKAP5L PRRC2B

2.18e-0721867733378226
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FCHSD2 CAMKK2 FAM168A ARHGEF9 ULK1 SRRM2 ULK2 PRRC2B

1.17e-0640767812693553
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ZNF469 ZNF609 BAIAP2L1 ATXN2 PLCH2 ZMIZ2 BSN POM121C

1.76e-0643067835044719
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RANBP10 ATXN2 RANBP9 CTNND2 RAPGEF2 CCDC6 BSN AFF4 PRRC2B RAI1 MAPK8IP3

2.16e-06963671128671696
Pubmed

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).

ULK1 ULK2

3.66e-06267230782972
Pubmed

Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.

ULK1 ULK2

3.66e-0626729600096
Pubmed

Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes.

ULK1 ULK2

3.66e-06267224135897
Pubmed

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy.

ULK1 ULK2

3.66e-06267221460635
Pubmed

Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes.

ULK1 ULK2

3.66e-06267233149253
Pubmed

ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.

ULK1 ULK2

3.66e-06267227153534
Pubmed

Association of LPP and ZMIZ1 Gene Polymorphism with Celiac Disease in Subjects from Punjab, Pakistan.

LPP ZMIZ1

3.66e-06267239062631
Pubmed

Spatial and temporal expression of Zimp7 and Zimp10 PIAS-like proteins in the developing mouse embryo.

ZMIZ2 ZMIZ1

3.66e-06267218053775
Pubmed

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.

ULK1 ULK2

3.66e-06267223291478
Pubmed

Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle.

ULK1 ULK2

3.66e-06267234658916
Pubmed

A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons.

ULK1 ULK2

3.66e-06267210624947
Pubmed

A human MAP kinase interactome.

KIF26A ARHGEF9 RANBP9 RAPGEF2 POM121C NCKAP5L HCK ZYX

4.35e-0648667820936779
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

ZNF469 AMOT RTN4 POLR2A NACA CCDC6 BSN SRRM2 ZYX

4.45e-0665367933742100
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CAMKK2 MAP2 RTN4 CTNND2 BSN SRRM2 MAPK8IP3

4.82e-0634767717114649
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ZNF609 ATXN2 POLR2A LPP TNS2 CCDC6 PPP1R13L SRRM2 NCKAP5L ZYX PRRC2B

4.89e-061049671127880917
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

BAIAP2L1 MAP2 AMOT LPP RAPGEF2 CCDC6 MCRIP1 SRRM2 NCKAP5L ZYX

5.69e-06861671036931259
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP2 CTNND2 BSN SRRM2 PRRC2B MAPK8IP3

5.72e-0623167616452087
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

POLR2A LPP CCDC6 SRRM2 HCK

6.05e-0613367515144186
Pubmed

A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.

NACA RANBP9 RAPGEF2 AFF4

9.33e-066867422779921
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

RANBP10 ATXN2 NACA RANBP9 CCDC6 ZYX PDHX PRRC2B

1.08e-0555167834728620
Pubmed

Long non‑coding RNA growth arrest‑specific 5 (GAS5) acts as a tumor suppressor by promoting autophagy in breast cancer.

ULK1 ULK2

1.10e-05367232705220
Pubmed

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases.

ULK1 ULK2

1.10e-05367221690395
Pubmed

The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion.

SPANXD SPANXC

1.10e-05367226895102
Pubmed

Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β).

CAMKK2 ULK1

1.10e-05367223027865
Pubmed

Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function.

ULK1 ULK2

1.10e-05367235104184
Pubmed

Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer.

ULK1 ULK2

1.10e-05367239213022
Pubmed

Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells.

ULK1 ULK2

1.10e-05367226213203
Pubmed

ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer.

ULK1 ULK2

1.10e-05367232516362
Pubmed

Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling.

CAMKK2 ULK1

1.10e-05367233531625
Pubmed

Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling.

CAMKK2 ULK1

1.10e-05367226103054
Pubmed

AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.

ULK1 AFF4

1.10e-05367237731335
Pubmed

An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.

ULK1 ULK2

1.10e-05367237846507
Pubmed

The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor.

ZMIZ2 ZMIZ1

1.10e-05367217584785
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

ZNF609 AMOT ZMIZ2 ZMIZ1 PRRC2B

1.16e-0515267538360978
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ZNF609 SUGP1 MED14 AFF4 PRRC2B RAI1

1.33e-0526867633640491
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

ZNF609 SUGP1 PRRC2B

1.34e-052467333722704
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

RTN4 POLR2A RANBP9 MED14 SRRM2 PRRC2B

1.42e-0527167625737280
Pubmed

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

MAP2 RTN4 CTNND2 BSN

2.16e-058467419165527
Pubmed

Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy.

ULK1 ULK2

2.19e-05467225925668
Pubmed

Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM.

RANBP10 RANBP9

2.19e-05467212147692
Pubmed

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127.

FOXN1 GATA3

2.19e-05467217013389
Pubmed

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.

LPP ZYX

2.19e-05467222665060
Pubmed

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.

ULK1 ULK2

2.19e-05467230979586
Pubmed

Modeling by disruption and a selected-for partner for the nude locus.

FOXN1 AFF4

2.19e-05467233369874
Pubmed

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death.

ULK1 ULK2

2.19e-05467221475306
Pubmed

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.

ULK1 ULK2

2.19e-05467218443221
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

ZNF609 ATXN2 SUSD2 ZMIZ1 POM121C PRRC2B RAI1

2.85e-0545767732344865
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ZNF609 BAIAP2L1 POLR2A NACA RANBP9 CCDC6 SRRM2

3.49e-0547267738943005
Pubmed

Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma.

ULK1 ULK2

3.64e-05567232203415
Pubmed

The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.

ZMIZ2 ZMIZ1

3.64e-05567216777850
Pubmed

Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.

PPP1R13L RAI1

3.64e-05567215885892
Pubmed

Atg101, a novel mammalian autophagy protein interacting with Atg13.

ULK1 ULK2

3.64e-05567219597335
Pubmed

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death.

ULK1 ULK2

3.64e-05567222493260
Pubmed

Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27.

SPANXD SPANXC

3.64e-05567216251457
Pubmed

Binding of liganded vitamin D receptor to the vitamin D receptor interacting protein coactivator complex induces interaction with RNA polymerase II holoenzyme.

POLR2A MED14

3.64e-05567210753860
Pubmed

Sexually dimorphic gene expression of the Zimp7 and Zimp10 genes in embryonic gonads.

ZMIZ2 ZMIZ1

3.64e-05567219931425
Pubmed

Differential nuclear localization of the cancer/testis-associated protein, SPAN-X/CTp11, in transfected cells and in 50% of human spermatozoa.

SPANXD SPANXC

3.64e-05567211133693
Pubmed

Genomic organization, incidence, and localization of the SPAN-x family of cancer-testis antigens in melanoma tumors and cell lines.

SPANXD SPANXC

3.64e-05567214734458
Pubmed

A role for BCL2L13 and autophagy in germline purifying selection of mtDNA.

ULK1 ULK2

3.64e-05567236608143
Pubmed

SPANX gene variation in fertile and infertile males.

SPANXD SPANXC

3.64e-05567220073942
Pubmed

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.

ULK1 ULK2

3.64e-05567227203176
Pubmed

Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.

FOXN1 GATA3

3.64e-05567227053161
Pubmed

JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains.

MAP2 MAPK8IP3

3.64e-05567221685723
Pubmed

The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines.

SPANXD SPANXC

3.64e-05567212758128
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF609 RAPGEF2 KDM6B SRRM2

5.00e-051046749205841
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AMOT RNF44 TNS2 MAPK8IP3

5.00e-0510467410470851
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

POLR2A GATA3 MED14 SRRM2 POM121C AFF4

5.13e-0534167632971831
Pubmed

Role of Unc51.1 and its binding partners in CNS axon outgrowth.

ULK1 ULK2

5.46e-05667215014045
Pubmed

The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting.

MAP2 BSN

5.46e-05667231787876
Pubmed

A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription.

ZMIZ2 ZMIZ1

5.46e-05667220159969
Pubmed

Annexin A2 Regulates Autophagy in Pseudomonas aeruginosa Infection through the Akt1-mTOR-ULK1/2 Signaling Pathway.

ULK1 ULK2

5.46e-05667226371245
Pubmed

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

ULK1 ULK2

5.46e-05667227046250
Pubmed

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

ULK1 ULK2

5.46e-05667219225151
Pubmed

Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65.

MAP2 BSN

5.46e-05667224554721
Pubmed

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

ULK1 ULK2

5.46e-05667218936157
Pubmed

Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons.

ULK1 ULK2

5.46e-05667217389358
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

POLR2A MED14 SRRM2 PRRC2B

5.59e-0510767420508642
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF609 ZMIZ2 ZMIZ1 POM121C PRRC2B RAI1

6.02e-0535167638297188
Pubmed

Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus.

KIF26A GATA3 ROBO3

6.42e-054067326297811
Pubmed

Next-generation sequencing to generate interactome datasets.

FCHSD2 FAM168A RTN4 RANBP9 SCEL TRIM29 HCK ZYX PDHX PRRC2B

6.59e-051147671021516116
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RTN4 POLR2A LPP NACA SUGP1 POM121C ZYX AFF4 PRRC2B

7.41e-0593467933916271
Pubmed

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.

ULK1 ULK2

7.63e-05767228877469
Pubmed

Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.

ULK1 ULK2

7.63e-05767228389568
Pubmed

Regional localization of the nu mutation on mouse chromosome 11.

FOXN1 POLR2A

7.63e-0576728423056
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZNF609 POLR2A LPP NACA SUGP1 PPP1R13L MCRIP1 NCKAP5L

8.17e-0573367834672954
Pubmed

Human transcription factor protein interaction networks.

ZNF609 ATXN2 ZMIZ2 NACA GATA3 SUGP1 ZMIZ1 MCRIP1 SRRM2 POM121C PRRC2B

8.40e-051429671135140242
Pubmed

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs.

POLR2A PRRC2B

1.02e-04867227365365
Pubmed

Diversity of two forms of DNA methylation in the brain.

MAP2 POLR2A

1.02e-04867224653733
Pubmed

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.

POLR2A AFF4

1.02e-04867221873227
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

BAIAP2L1 RTN4 LPP SCEL PPP1R13L TRIM29 ZYX

1.08e-0456567725468996
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

MAP2 RTN4 NACA CTNND2 SRRM2

1.15e-0424667515345747
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

RTN4 LPP TNS2 CCDC6 PPP1R13L MCRIP1 SRRM2

1.18e-0457367728330616
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF609 FAM168A MAP2 ATXN2 LPP ARHGEF9 ZMIZ1 RAPGEF2 AFF4 RAI1 MAPK8IP3

1.21e-041489671128611215
InteractionTNKS interactions

AMOT PLCH2 RANBP9 TNS2 RAPGEF2 MAPK8IP3

1.34e-06105676int:TNKS
InteractionNEDD4 interactions

RANBP10 CAMKK2 BAIAP2L1 MAP2 AMOT POLR2A NACA TTYH2 ULK1 RAPGEF2 KDM6B

1.64e-065446711int:NEDD4
InteractionLPXN interactions

ATXN2 LPP TNS2 RAPGEF2 CCDC6 ZYX

2.28e-06115676int:LPXN
InteractionUNK interactions

ATXN2 RTN4 POLR2A RANBP9 MED14 CCDC6 MCRIP1 SRRM2 PRRC2B

7.92e-06408679int:UNK
InteractionSEC16A interactions

ATXN2 AMOT ULK1 CCDC6 PPP1R13L TRIM29 ULK2 ZYX PRRC2B

1.12e-05426679int:SEC16A
InteractionCRX interactions

ZNF609 NRL ZMIZ2 TNS2 ZMIZ1 PRRC2B RAI1

2.12e-05254677int:CRX
InteractionPIN1 interactions

FOXN1 AMOT ZMIZ2 POLR2A TNS2 CCDC6 SRRM2 RAI1

3.88e-05383678int:PIN1
InteractionNRXN1 interactions

MAP2 RTN4 CTNND2 BSN TRIM29

6.49e-05127675int:NRXN1
InteractionNR3C1 interactions

RTN4 RANBP9 SUGP1 MED14 CTNND2 CCDC6 BSN MCRIP1 POM121C PDHX PRRC2B RAI1

7.78e-059746712int:NR3C1
CytobandXq27.1

SPANXD SPANXC CXorf66

1.99e-0617673Xq27.1
CytobandEnsembl 112 genes in cytogenetic band chrXq27

SPANXD SPANXC CXorf66

3.29e-0491673chrXq27
GeneFamilyZinc fingers MIZ-type

ZMIZ2 ZMIZ1

1.05e-04741285
GeneFamilyLIM domain containing

LPP SCEL ZYX

3.22e-04594131218
GeneFamilyAutophagy related

ULK1 ULK2

2.53e-03334121022
ToppCellfacs-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 SCEL KDM6B PPP1R13L TRIM29 SRRM2

4.49e-071926761f81b356520b5506051383d37fae204d59795336
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SUSD2 SCEL PPP1R13L

7.87e-06181675b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 POLR2A KDM6B TRIM29 NCKAP5L

8.98e-06186675bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SUSD2 SCEL PPP1R13L

8.98e-061866753aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 POLR2A KDM6B TRIM29 NCKAP5L

9.70e-06189675965e0e388251e7318f8b463816dc96ccb4658677
ToppCellfacs-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 SCEL KDM6B TRIM29 SRRM2

1.10e-05194675842636fcc64eb8f04eb4e30b6eb70410050880e9
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

FCHSD2 ZNF469 TTYH2 NCKAP5L ZYX

1.13e-051956755562665dd3beb70e2358aa32611a337bef5731c1
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HOXD1 BAIAP2L1 MAP2 SUSD2 SCEL

1.21e-05198675691a2f1779225e5519155460eeb6a2aac5f67a92
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HOXD1 BAIAP2L1 MAP2 SUSD2 SCEL

1.21e-05198675aed0476248e9637897eefb1623ec4035f2dacd82
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HOXD1 BAIAP2L1 MAP2 SUSD2 SCEL

1.21e-05198675e115eea04012e9e492e923ed080e1723c38d14fd
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HOXD1 BAIAP2L1 MAP2 SUSD2 SCEL

1.21e-0519867533d1e0b6f57663544bee0ffdde83a65da764d44c
ToppCellSevere_COVID-19-Epithelial-AT1/AT2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

HOXD1 BAIAP2L1 MAP2 SUSD2 SCEL

1.21e-0519867543e33d28d9de5033bd00d39be953542a225236ed
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

FOXN1 GATA3 SCEL PPP1R13L TRIM29

1.24e-051996756be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCellAT1-AT2_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MAP2 HIF3A SCEL CTNND2

6.77e-05145674cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NRL RUBCNL ROBO3

7.41e-055467398b31718fa200432cf86b59a52484da101219f96
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NRL RUBCNL ROBO3

7.41e-0554673872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

HOXD1 MAP2 SCEL CTNND2

8.77e-05155674010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH2 KDM6B SRRM2 SERPINA9

1.02e-04161674d02f8c01b26158a06e109eb603b0fe76372ec983
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BAIAP2L1 MAP2 SCEL HCK

1.20e-041686748c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 SUSD2 SCEL CTNND2

1.22e-04169674cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

BAIAP2L1 ATOH8 SUSD2 SCEL

1.25e-041706744cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

BAIAP2L1 ATOH8 SUSD2 SCEL

1.25e-0417067436c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXN1 SCEL PPP1R13L TRIM29

1.34e-041736741b2508cc890430bd4b2cf232c633928edb86c57e
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXN1 SCEL PPP1R13L TRIM29

1.59e-041816746b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FCHSD2 KIF26A AMOT ATOH8

1.59e-04181674136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXN1 SCEL PPP1R13L TRIM29

1.59e-04181674f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SUSD2 SCEL

1.63e-04182674cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

MAP2 ATOH8 SUSD2 SCEL

1.63e-04182674e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

FCHSD2 RUBCNL TTYH2 HCK

1.66e-04183674703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SUSD2 SCEL

1.66e-04183674274483009b309289e4cb84beedf6806430db6ff6
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SUSD2 SCEL

1.66e-04183674ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATOH8 ZMIZ2 KDM6B RAI1

1.66e-04183674f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

FCHSD2 RUBCNL TTYH2 HCK

1.66e-04183674b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MAP2 ATOH8 SCEL CTNND2

1.66e-041836746821dca076318115d360ff426eb1218cfe104063
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SCEL PPP1R13L

1.73e-041856743bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 SCEL PPP1R13L TRIM29

1.73e-04185674657fd191ed160f8620d57b33820ec7222806f289
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SCEL PPP1R13L

1.73e-04185674c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLR2A LPP TRIM29 AFF4

1.73e-04185674eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

MAP2 ATOH8 SUSD2 SCEL

1.77e-04186674df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL TTYH2 HCK ZYX

1.81e-041876748249b2a69c728e4e04fb14b490c320e644d2252f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 ATOH8 SCEL PPP1R13L

1.81e-0418767458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BAIAP2L1 LRRC8A PPP1R13L TRIM29

1.81e-04187674a6a112689d1c9049f57935ad9d2f4955538427de
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

MAP2 ATOH8 SUSD2 SCEL

1.81e-041876743a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

MAP2 SUSD2 SCEL CTNND2

1.84e-04188674be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellfacs-MAT-Fat-18m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH2 LRRC8A KDM6B ZYX

1.84e-041886747f0cda7aab442aa9511d4c35569ec2389e014a71
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HOXD1 HIF3A RGP1 NCKAP5L

1.88e-04189674bccb3481ffed597c845fe860da658505316105b5
ToppCellCOPD-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

MAP2 ATOH8 SUSD2 SCEL

1.88e-0418967414e8e57e4db336fbef005270647983b4edf407c0
ToppCellSupraBC-Differ-KC|World / shred by cell class for mouse tongue

FOXN1 MAP2 SCEL SERPINA9

1.88e-041896746412741b88e241304033b41effca0c77a374d907
ToppCellfacs-Tongue-nan-3m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXN1 MAP2 SCEL SERPINA9

1.92e-04190674719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 ATOH8 SUSD2 SCEL

1.96e-04191674a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 SCEL PPP1R13L TRIM29

1.96e-04191674ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellfacs-Tongue-nan-18m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXN1 MAP2 SCEL SERPINA9

1.96e-0419167402f24202f9fdd46c648265a5b3b6f9066aa009fc
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 KDM6B TRIM29 NCKAP5L

1.96e-041916742f733d510a4862565a817f59829d8387d7ea26d9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP9 SCEL PPP1R13L TRIM29

1.96e-04191674fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 KDM6B TRIM29 NCKAP5L

1.96e-041916748691eba35793e4e90f93d50c2145847ee51289f7
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAIAP2L1 GATA3 LRRC8A TRIM29

2.00e-0419267418546b4d5e39aafa97186104d47cfda02eb5f4b5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ATXN2 HIF3A SRRM2 AFF4

2.00e-04192674916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MAP2 RTN4 LPP KDM6B

2.00e-041926748b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellfacs-SCAT-Fat-18m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH2 LRRC8A KDM6B SRRM2

2.00e-04192674cd004f8b00ebdb7f6d889f58d2cd6cbab4b809dd
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MAP2 ATOH8 SUSD2 SCEL

2.00e-041926740444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCHSD2 RUBCNL CCDC6 KDM6B

2.04e-04193674bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCHSD2 ZNF609 FAM168A LPP

2.04e-04193674779276e775cb2492e8dd36436295a536084a6415
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAIAP2L1 PLCH2 GATA3 TRIM29

2.04e-04193674268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATOH8 ZMIZ1 TRIM29 ZYX

2.04e-04193674eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ATXN2 HIF3A SRRM2 AFF4

2.04e-04193674e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCH2 GATA3 CTNND2 TRIM29

2.08e-041946741531dcace28a14bd700e909a027426a8cee20337
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATOH8 ZMIZ1 TRIM29 ZYX

2.08e-041946745d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

MAP2 SUSD2 SCEL CTNND2

2.12e-0419567407a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 ATOH8 SUSD2 SCEL

2.12e-0419567468f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

MAP2 ATOH8 SUSD2 SCEL

2.12e-04195674569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MAP2 SUSD2 SCEL CTNND2

2.12e-04195674b65511770ed67f7447847e2187555b362988af45
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 ATOH8 SUSD2 SCEL

2.12e-041956742a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCellAT1|World / shred by cell class for parenchyma

SUSD2 PLCH2 SCEL TRIM29

2.16e-041966742bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PLCH2 LRRC8A PPP1R13L TRIM29

2.16e-041966743b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 ATOH8 SUSD2 SCEL

2.16e-04196674eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MAP2 SUSD2 SCEL CTNND2

2.16e-04196674150554fa06868d29b0608189862eef6505ba757f
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ATOH8 CD46 HIF3A RAPGEF2

2.20e-0419767466339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCelldistal-1-Epithelial-Alveolar_Epithelial_Type_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP2 SUSD2 SCEL CTNND2

2.20e-04197674d44b7dc7c6416ed9466889374c3ae39f43ac8bb6
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF469 ZMIZ1 KDM6B HCK

2.20e-04197674515a2d0ee2bd3fc0a5a0c315e2b0c752e6af7406
ToppCellASK452-Epithelial-Type_1|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

MAP2 SUSD2 SCEL PPP1R13L

2.20e-04197674dc0a6dca4af6b216357b06f67203274f8b2a8bb0
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXN1 LRRC8A PPP1R13L TRIM29

2.20e-0419767461c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF469 ZMIZ1 KDM6B HCK

2.20e-04197674bfa04e5f4156a01df4217b1f59676edb0a7563e1
ToppCellnormal_Lung-Epithelial_cells-AT1|Epithelial_cells / Location, Cell class and cell subclass

MAP2 ATOH8 SUSD2 SCEL

2.20e-041976747d19b93d6853828e2a036e37c4887edb1de4503c
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GREB1L HOXD1 MAP2 BSN

2.20e-0419767449689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF469 ZMIZ1 KDM6B HCK

2.20e-041976744fccdc69ab4b966de6465f06677435e6f6e6abcd
ToppCelldroplet-Skin-nan-21m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NACA GATA3 SCEL TRIM29

2.25e-04198674e2d1ef4a4c89ce53b47d7d5b8a45e71d3117e1b1
ToppCellCOVID-19-Epithelial-AT2,_AT1_cells|COVID-19 / Condition, Lineage and Cell class

BAIAP2L1 MAP2 SUSD2 SCEL

2.25e-041986747e6f089e71e70190ff8486341ab06719d7741467
ToppCelldroplet-Skin-nan-21m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NACA GATA3 SCEL TRIM29

2.25e-0419867438a58e6eaae89ce1cadf2e04169c974e13587e50
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP2 LRRC8A TNS2 HIF3A

2.29e-04199674a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell(08)_Brush+PNEC|World / shred by cell type by condition

ZNF609 GYS2 ZMIZ1 HCK

2.29e-04199674f2e33cb569c25fc2732722cac295647e9bd8738f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

FCHSD2 ZNF609 LPP RAPGEF2

2.29e-0419967494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP2 ATOH8 SUSD2 SCEL

2.33e-04200674b652bc73adfdeccbdcd74497ab6e2085e5c95e88
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

PLCH2 LRRC8A PPP1R13L TRIM29

2.33e-042006745cea84581201cee7ba8141b96e65864f4fd67113
ToppCellproximal-3-Epithelial-Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLCH2 LRRC8A PPP1R13L TRIM29

2.33e-042006748083047c213488e40b975013e3c5c43f7c0c15b2
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP2 ATOH8 SUSD2 SCEL

2.33e-04200674c1345893e6947ccf9b41282d0e4428dbfb8bcc27
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

MAP2 ATOH8 SUSD2 SCEL

2.33e-04200674b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCellproximal-Epithelial-Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLCH2 LRRC8A PPP1R13L TRIM29

2.33e-04200674c6a491d3e2dae6618f25dc3c9aac08f657348168
ToppCellproximal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP2 ATOH8 SUSD2 SCEL

2.33e-0420067451f8fc43c069f2c4e75588d28ae6deb5d7ed2c86
ToppCellproximal-Epithelial-Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLCH2 LRRC8A PPP1R13L TRIM29

2.33e-04200674f5d48f521abbd1e07de05f2b3768ad2f9675f1e1
ComputationalNeighborhood of MAP4K4

RTN4 TTYH2 LRRC8A TNS2 ULK2 MAPK8IP3

1.08e-04172486GCM_MAP4K4
ComputationalNeighborhood of DLG1

RTN4 TNS2 RAPGEF2 MAPK8IP3

4.11e-0479484GCM_DLG1
ComputationalNeighborhood of PTK2

RTN4 TTYH2 TNS2 ULK2 MAPK8IP3

4.48e-04145485GCM_PTK2
Drugyohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA

RANBP10 FAM168A LPP CTNND2 KDM6B PPP1R13L SRRM2 ULK2 ZYX

5.49e-091946791119_UP
DrugMetoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; PC3; HT_HG-U133A

GREB1L HOXD1 LPP SUGP1 CCDC6 TRIM29 HHLA1

1.83e-061976774285_UP
DrugVancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A

FCHSD2 ZNF609 LPP ARHGEF9 SUGP1 TNS2 CTNND2

1.96e-061996772858_DN
DrugDoxylamine succinate [562-10-7]; Up 200; 10.2uM; HL60; HG-U133A

ZNF609 POLR2A SUGP1 MED14 RAPGEF2 KDM6B PPP1R13L

1.96e-061996771973_UP
Drugfullerene C60

FOXN1 RANBP10 ZNF609 FAM168A KIF26A ZMIZ2 POLR2A GYS2 TTYH2 ULK1 HIF3A BSN KDM6B AFF4 PRRC2B MAPK8IP3

5.19e-0614986716ctd:C069837
DrugLuteolin [491-70-3]; Down 200; 14uM; PC3; HT_HG-U133A

FCHSD2 ZNF609 SUGP1 KDM6B SRRM2 MAPK8IP3

2.10e-051916766658_DN
Drug0175029-0000 [211245-78-2]; Up 200; 10uM; PC3; HT_HG-U133A

NACA MED14 CD46 ROBO3 TRIM29 MAPK8IP3

2.16e-051926766875_UP
DrugGraveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A

GREB1L ZNF609 MAP2 SUGP1 CTNND2 HHLA1

2.23e-051936764276_UP
DrugAlbendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A

ZNF609 MAP2 SUGP1 MED14 ZYX AFF4

2.30e-051946767164_UP
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A

GREB1L ZNF609 GATA3 CD46 CTNND2 MAPK8IP3

2.30e-051946763725_DN
DrugMinaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A

GREB1L ZNF609 NRL AMOT ZMIZ2 SUGP1

2.36e-051956764814_UP
DrugAG-028671 [847803-03-6]; Up 200; 10uM; PC3; HT_HG-U133A

GREB1L ZNF609 PLCH2 SUGP1 TNS2 TRIM29

2.36e-051956766557_UP
DrugMidodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A

ZNF609 FAM168A ZMIZ2 SUGP1 TRIM29 PRRC2B

2.36e-051956762087_UP
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

ZNF609 POLR2A NACA CTNND2 KDM6B TRIM29

2.43e-051966765574_DN
DrugIsoxicam [34552-84-6]; Up 200; 12uM; PC3; HT_HG-U133A

FCHSD2 ZNF609 CAMKK2 SUGP1 TNS2 SRRM2

2.43e-051966761820_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

GREB1L ZNF609 ZMIZ2 POLR2A SUGP1 CTNND2

2.43e-051966764281_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A

FAM168A ZMIZ2 ARHGEF9 TNS2 KDM6B SRRM2

2.43e-051966763849_UP
DrugMonocrotaline [315-22-0]; Down 200; 12.2uM; PC3; HT_HG-U133A

RANBP10 FAM168A POLR2A ARHGEF9 ROBO3 SRRM2

2.43e-051966767127_DN
DrugNalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; HL60; HG-U133A

HOXD1 ATXN2 POLR2A CD46 RAPGEF2 PRRC2B

2.43e-051966761379_DN
DrugClorsulon [60200-06-8]; Down 200; 10.6uM; HL60; HG-U133A

FCHSD2 ZNF609 HOXD1 RNF44 POLR2A RGP1

2.43e-051966761735_DN
DrugMidecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A

ZNF609 ZMIZ2 TNS2 KDM6B AFF4 MAPK8IP3

2.50e-051976761526_DN
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

CAMKK2 ZMIZ2 ROBO3 TRIM29 HHLA1 ZYX

2.50e-051976765519_UP
DrugNicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZNF609 ARHGEF9 SUGP1 ULK2 ZYX AFF4

2.50e-051976763215_DN
DrugPiperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A

ZMIZ2 GATA3 SUGP1 MED14 CTNND2 SRRM2

2.50e-051976763763_DN
DrugLithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A

GREB1L CAMKK2 PLCH2 RUBCNL SUGP1 MAPK8IP3

2.50e-051976763899_UP
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A

LPP MED14 RAPGEF2 SRRM2 ZYX MAPK8IP3

2.57e-051986765220_DN
DrugFursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ZNF609 FAM168A NRL ZMIZ2 ARHGEF9 SUGP1

2.57e-051986767349_UP
DrugCP-863187 [668981-07-5]; Up 200; 10uM; MCF7; HT_HG-U133A

RANBP10 ZMIZ2 LPP ARHGEF9 MED14 CTNND2

2.57e-051986767553_UP
DrugViomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A

POLR2A TNS2 HIF3A TRIM29 SRRM2 MAPK8IP3

2.65e-051996763541_UP
DrugAcebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HG-U133A

FAM168A ATXN2 LPP MED14 KDM6B PPP1R13L

2.65e-051996761911_DN
DrugLevodopa [59-92-7]; Down 200; 20.2uM; HL60; HG-U133A

ATXN2 MED14 CD46 RAPGEF2 PDHX MAPK8IP3

2.65e-051996761972_DN
Druggenistein; Down 200; 10uM; MCF7; HT_HG-U133A

CAMKK2 LPP TNS2 RAPGEF2 ULK2 ZYX

2.65e-051996761660_DN
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; PC3; HT_HG-U133A

ZNF609 FAM168A SUGP1 KDM6B RGP1 SRRM2

2.65e-051996765789_DN
DrugProglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A

ZNF609 HOXD1 ZMIZ2 SUGP1 CTNND2 MAPK8IP3

2.65e-051996763780_DN
DrugLY 294002; Down 200; 10uM; PC3; HT_HG-U133A

ZNF609 ARHGEF9 GATA3 SUGP1 ZYX PRRC2B

2.65e-051996761227_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A

FAM168A ARHGEF9 SUGP1 TNS2 RAPGEF2 CCDC6

2.72e-052006762677_DN
DrugEthosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A

ZMIZ2 GATA3 SUGP1 KDM6B TRIM29 MAPK8IP3

2.72e-052006762116_UP
Drugalpha-CaM

CAMKK2 MAP2 CTNND2 ZYX

3.36e-0562674CID000196705
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

FCHSD2 ZNF609 ATXN2 ZMIZ1 RAPGEF2

1.49e-041716757535_DN
DrugNiclosamide [50-65-7]; Up 200; 12.2uM; HL60; HG-U133A

LPP NACA RAPGEF2 SRRM2 HCK

1.54e-041726751998_UP
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ZNF609 GATA3 TNS2 ZMIZ1 SRRM2

1.66e-041756756891_DN
DrugHycanthone [3105-97-3]; Down 200; 11.2uM; HL60; HG-U133A

LPP NACA SUGP1 CD46 PRRC2B

2.27e-041876751614_DN
Drugcelastrol; Down 200; 2.5uM; MCF7; HT_HG-U133A_EA

FCHSD2 CAMKK2 POLR2A MED14 PRRC2B

2.27e-04187675887_DN
Drugtroglitazone; Down 200; 10uM; PC3; HT_HG-U133A

GATA3 SUGP1 MED14 SCEL PPP1R13L

2.32e-041886754456_DN
DrugAmitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; HL60; HT_HG-U133A

RANBP10 ZNF609 SUGP1 KDM6B MAPK8IP3

2.32e-041886751865_DN
DrugPrednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ZMIZ2 SUGP1 ROBO3 TRIM29 ULK2

2.38e-041896754400_DN
DrugProstaglandin E1; Up 200; 10uM; PC3; HT_HG-U133A

ZNF609 LPP SUGP1 TRIM29 MAPK8IP3

2.44e-041906756555_UP
DrugTiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A

GREB1L ZMIZ2 CTNND2 TRIM29 ULK2

2.50e-041916752840_UP
DrugProadifen hydrochloride [62-68-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A

ZNF609 SUGP1 MED14 RAPGEF2 KDM6B

2.50e-041916757165_UP
Drug6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

MAP2 POLR2A ZMIZ1 KDM6B

2.52e-04104674ctd:C000595015
Drugprazosin hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA

SUGP1 CD46 CCDC6 PPP1R13L MAPK8IP3

2.56e-04192675942_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

MED14 TNS2 KDM6B ZYX PRRC2B

2.62e-041936754186_DN
DrugCanrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A

ZNF609 FAM168A SUGP1 TNS2 CTNND2

2.62e-041936756783_DN
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

ZMIZ2 SUGP1 TNS2 KDM6B ZYX

2.62e-041936754241_DN
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A

ZMIZ2 SUGP1 TNS2 TRIM29 MAPK8IP3

2.62e-041936756846_UP
DrugNilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A

CAMKK2 POLR2A LPP RAPGEF2 SRRM2

2.68e-041946755362_UP
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A

GREB1L HOXD1 ATXN2 GATA3 ROBO3

2.68e-041946753807_DN
DrugAdamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

FCHSD2 ZMIZ2 SUGP1 CTNND2 SRRM2

2.68e-041946753280_DN
DrugClobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A

GREB1L POLR2A SRRM2 ULK2 MAPK8IP3

2.68e-041946756835_UP
Drug5194442; Up 200; 20uM; PC3; HT_HG-U133A

LPP ARHGEF9 SUGP1 MED14 RAPGEF2

2.68e-041946756553_UP
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

GREB1L ZNF609 ZMIZ2 CTNND2 ZYX

2.68e-041946752621_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

GREB1L KDM6B TRIM29 SRRM2 MAPK8IP3

2.68e-041946753354_DN
DrugCarbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A

ZNF609 SUGP1 CCDC6 ULK2 AFF4

2.68e-041946751805_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A

ZNF609 ZMIZ2 TNS2 TRIM29 ZYX

2.68e-041946754291_DN
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

ATXN2 SUGP1 RAPGEF2 KDM6B RGP1

2.68e-041946754529_DN
Drugtroglitazone; Down 200; 10uM; MCF7; HT_HG-U133A

SUGP1 CTNND2 KDM6B ZYX MAPK8IP3

2.75e-041956751657_DN
DrugCP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A

MAP2 ZMIZ2 SUGP1 TNS2 AFF4

2.75e-041956753909_DN
DrugSulfaphenazole [526-08-9]; Down 200; 12.8uM; HL60; HT_HG-U133A

FAM168A CD46 KDM6B PRRC2B MAPK8IP3

2.75e-041956751836_DN
DrugGuanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; PC3; HT_HG-U133A

GREB1L ZNF609 GATA3 CTNND2 MAPK8IP3

2.75e-041956754660_DN
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A

GREB1L ZNF609 LPP HIF3A RAPGEF2

2.75e-041956754298_UP
DrugVitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A

FAM168A POLR2A TNS2 RAPGEF2 ZYX

2.75e-041956752810_DN
DrugNialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A

MAP2 ARHGEF9 TNS2 TRIM29 MAPK8IP3

2.75e-041956753871_DN
DrugST021200; Up 200; 10uM; MCF7; HT_HG-U133A

ZNF609 LPP ARHGEF9 MED14 CD46

2.75e-041956757554_UP
DrugProcyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

ZNF609 ZMIZ2 SUGP1 TRIM29 ZYX

2.75e-041956754817_UP
DrugLisinopril [83915-83-7]; Up 200; 9uM; MCF7; HT_HG-U133A

GREB1L FCHSD2 ZNF609 SUGP1 ULK2

2.75e-041956757403_UP
DrugZimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HG-U133A

ATXN2 RANBP9 TNS2 TRIM29 HHLA1

2.81e-041966751930_UP
DrugCefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; MCF7; HT_HG-U133A

RANBP10 ZMIZ2 SUGP1 AFF4 MAPK8IP3

2.81e-041966754718_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A

LPP GATA3 SUGP1 CTNND2 AFF4

2.81e-041966754524_UP
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A

GREB1L FOXN1 ZNF609 SUGP1 RAI1

2.81e-041966753545_UP
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A

PLCH2 ZMIZ2 TRIM29 HHLA1 MAPK8IP3

2.81e-041966753371_UP
DrugProbucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZNF609 ARHGEF9 SUGP1 TNS2 ZYX

2.81e-041966755261_DN
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

RANBP10 ZNF609 ARHGEF9 SUGP1 RAPGEF2

2.81e-041966751629_DN
DrugCorynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; PC3; HT_HG-U133A

SUGP1 MED14 ROBO3 KDM6B ZYX

2.81e-041966754227_DN
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

ZMIZ2 MED14 TNS2 RGP1 ULK2

2.81e-041966751021_DN
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A

ZMIZ2 SUGP1 SRRM2 ULK2 AFF4

2.81e-041966756637_DN
Drugsodium 4-phenylbutyrate; Up 200; 100uM; HL60; HG-U133A

AMOT LPP HIF3A KDM6B TRIM29

2.81e-04196675363_UP
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A

ZMIZ2 SUGP1 RAPGEF2 TRIM29 MAPK8IP3

2.81e-041966755974_DN
DrugPilocarpine nitrate [148-72-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A

ZNF609 SUGP1 CTNND2 ZYX PRRC2B

2.81e-041966755341_UP
Drug6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A

RANBP10 SUGP1 MED14 RAPGEF2 KDM6B

2.81e-041966752925_DN
Drugikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA

GREB1L ZMIZ2 SUGP1 TNS2 SCEL

2.81e-04196675918_UP
DrugBromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; PC3; HT_HG-U133A

ARHGEF9 SUGP1 CTNND2 SRRM2 PRRC2B

2.88e-041976754604_DN
DrugGallamine triethiodide [65-29-2]; Up 200; 4.4uM; PC3; HT_HG-U133A

GATA3 SUGP1 KDM6B TRIM29 AFF4

2.88e-041976752059_UP
DrugEtofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A

NACA CCDC6 KDM6B ZYX PRRC2B

2.88e-041976752093_DN
DrugAjmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ZNF609 FAM168A ZMIZ2 SUGP1 TNS2

2.88e-041976757484_UP
DrugEthisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ZMIZ2 SUGP1 ROBO3 RAPGEF2 SRRM2

2.88e-041976752326_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

ZNF609 HOXD1 KDM6B PPP1R13L SRRM2

2.88e-041976751732_DN
DrugICI 182,780; Up 200; 1uM; MCF7; HG-U133A

GREB1L RANBP10 ZNF609 SUGP1 RGP1

2.88e-04197675367_UP
DrugCiprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A

GATA3 SUGP1 KDM6B SRRM2 MAPK8IP3

2.88e-041976756700_DN
DrugCefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

FAM168A CTNND2 ROBO3 RGP1 ZYX

2.88e-041976752235_DN
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

GREB1L ZMIZ2 TRIM29 SRRM2 ZYX

2.88e-041976753355_DN
Diseaseanthropometric measurement

ZNF469 ATXN2 POLR2A ZMIZ1 BSN

3.28e-05168645EFO_0004302
Diseaseinterleukin-23 measurement

ATXN2 LPP

6.91e-056642EFO_0020501
Diseaseserum gamma-glutamyl transferase measurement

CAMKK2 PCNX3 ZMIZ2 GYS2 ULK1 ZMIZ1 POM121C ZYX PDHX

1.51e-04914649EFO_0004532
Diseasemean platelet volume

PCNX3 ATXN2 ZMIZ2 POLR2A GYS2 NACA LRRC8A ZMIZ1 ULK2

3.40e-041020649EFO_0004584
DiseaseGenetic chronic primary adrenal insufficiency

ATXN2 LPP

3.56e-0413642Orphanet_101960
DiseaseCrohn's disease

FCHSD2 ATXN2 LPP HIF3A ZMIZ1 BSN

3.88e-04441646EFO_0000384
Diseasenodular sclerosis Hodgkin lymphoma

LPP GATA3

4.14e-0414642EFO_0004708
Diseaseobsolete_interleukin-12 subunit B measurement

ATXN2 LPP

4.14e-0414642EFO_0010787
Diseaseneuroimaging measurement

ZNF469 MAP2 ATXN2 ROBO3 RAPGEF2 RGP1 POM121C RAI1 MAPK8IP3

4.78e-041069649EFO_0004346
Diseasesusceptibility to childhood ear infection measurement

GATA3 CTNND2 BSN RAI1

5.28e-04171644EFO_0007904
DiseaseFeeding difficulties

POLR2A ZMIZ1

6.93e-0418642C0232466
Diseasemonocyte percentage of leukocytes

BAIAP2L1 ATXN2 LPP ZMIZ1 CCDC6 KDM6B ZYX

1.02e-03731647EFO_0007989
DiseaseC-reactive protein measurement

ZNF469 CAMKK2 ZMIZ2 GYS2 HIF3A ZMIZ1 BSN AFF4 MAPK8IP3

1.13e-031206649EFO_0004458
Diseaselymphocyte count

RANBP10 ZNF469 BAIAP2L1 ATXN2 RTN4 LPP GATA3 HIF3A ZMIZ1 RAI1

1.15e-0314646410EFO_0004587
DiseaseVitiligo

ATXN2 LPP ZMIZ1

1.39e-03101643EFO_0004208
Diseaseglucose measurement

ATXN2 ZMIZ2 RTN4 BSN PDHX

1.41e-03380645EFO_0004468
DiseaseHashimoto's thyroiditis

ATXN2 LPP

1.46e-0326642EFO_0003779
Diseaseeye measurement

ZNF469 ATXN2

1.57e-0327642EFO_0004731
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

RANBP10 ATXN2 SUGP1 RAI1

1.94e-03243644EFO_0004612, EFO_0020944
DiseaseOvarian Mucinous Adenocarcinoma

ULK1 HCK

2.07e-0331642C1335167
Diseasefear of minor pain measurement

RAPGEF2 HCK

2.07e-0331642EFO_0008340
DiseaseJT interval

LPP NACA ZMIZ1 RAI1

2.08e-03248644EFO_0007885

Protein segments in the cluster

PeptideGeneStartEntry
PPQPNDLYKNPTSSS

AMOT

201

Q4VCS5
PSIPNSAGKLTRPSY

CXorf66

146

Q5JRM2
TSPPTTEGFKYPRPS

GYS2

626

P54840
YTPSPSSSRPISPGL

CCDC6

356

Q16204
TYAAPRGSSPKQSPS

CTNND2

291

Q9UQB3
PSSQTPKYPESNRTP

AFF4

661

Q9UHB7
KGVNSARSVPPSYPP

ARHGEF9

456

O43307
RSPKSQDSYPVSPRP

RANBP9

466

Q96S59
GRSPSYSSTPSPLMP

RAI1

351

Q7Z5J4
PKSQDSYPGSPSLSP

RANBP10

356

Q6VN20
SLPTSPGILATSPYP

RUBCNL

146

Q9H714
YPNSTILPTPDTGPT

LRRC8A

81

Q8IWT6
PAPPTRPGESSYSSI

ATOH8

181

Q96SQ7
ASSASGPRPTYKPPV

CD46

311

P15529
GTPYKVPPTQSNTAP

FAM168A

106

Q92567
SSSSSPPPAKRPYPS

MAPK8IP3

581

Q9UPT6
AQGLPTSPSPCYTTP

NCKAP5L

516

Q9HCH0
ASPAPGTYPKSVSPA

HOXD1

181

Q9GZZ0
CPSPSSRPPSRYQSG

ATXN2

556

Q99700
STRPGPLPTTQYSPG

KDM6B

826

O15054
PDRGSTPTSPYSVPQ

BSN

146

Q9UPA5
PPKRPYGTQRTPSTA

PCNX3

481

Q9H6A9
PTAPSPLQATAGPSY

PDHX

241

O00330
RPGPPTASLGSTPYS

NRL

31

P54845
PYKPRPPQSSTGSTA

LPP

136

Q93052
PPPATRGTSTYPTDF

KIF26A

326

Q9ULI4
SDSNSPPIPYSQKPA

GREB1L

96

Q9C091
KQPGTSGAYPLTSPP

MED14

1011

O60244
SSAKSPLPSYPGANP

POM121C

931

A8CG34
SPGPLSVYPPASSSS

GATA3

126

P23771
YVPDPTSTIKPGPNS

HCK

51

P08631
SPKMPPAPSGRAYTS

BAIAP2L1

281

Q9UHR4
YNGKRTSSPRSPPSS

MCRIP1

11

C9JLW8
LPYSPVSSPQSSPRL

CAMKK2

126

Q96RR4
QPPSSPYPSPDKRSS

FCHSD2

661

O94868
AGPPSRPPRYSSSSI

PPP1R13L

61

Q8WUF5
SLPSSYRPAQPSPSA

PCARE

1011

A6NGG8
GRPQPPTLDPTSTSY

PCARE

1201

A6NGG8
SSSDSPPRPQPAFKY

RTN4

11

Q9NQC3
GTQTPSPTKATAPRY

HHLA1

396

C9JL84
NSGSFTFTPKPAPPS

SUSD2

226

Q9UGT4
TPKGGVRTSYQPSSP

TRIM29

476

Q14134
TPPTAANYPSSSRTP

SRRM2

2316

Q9UQ35
PTSPTLASYAAPGPS

RGP1

371

Q92546
PAGPSVYLSPSSKPV

FOXN1

631

O15353
RAYKPPAQTSPAGSP

HIF3A

196

Q9Y2N7
APSAYPRPSSTKSTP

SERPINA9

26

Q86WD7
PETSSGYSDPQPAPK

SPANXC

26

Q9NY87
SAPPSTPTPSAGKRS

SUGP1

111

Q8IWZ8
SPPTSPQSSPRKGYT

RAPGEF2

1116

Q9Y4G8
PETSSGYSDPQPAPK

SPANXD

26

Q9BXN6
GRASPPPTYSPSMRA

TTYH2

501

Q9BSA4
AVPTSSSQGRPPYPT

PLCH2

1021

O75038
PPPPGYNASSSTGTR

SCEL

166

O95171
PSRRETPSPTPSYGQ

ROBO3

1136

Q96MS0
YSTSAPGPALSPSVP

RNF44

236

Q7L0R7
SPTSPKGSTYSPTSP

POLR2A

1931

P24928
ASQQGSTPSLYPPPR

ZNF609

1396

O15014
VPSPQTYRPSSASPS

PRRC2B

2151

Q5JSZ5
ITPGTPPSYSSRTPG

MAP2

1601

P11137
SRTPGTPGTPSYPRT

MAP2

1611

P11137
SYPRTPHTPGTPKSA

MAP2

1621

P11137
SGPTRSIPGYPSSPL

ZMIZ2

356

Q8NF64
PQSRGTSPLQPGSYP

ZNF469

211

Q96JG9
YSPQPSRPGSLGTSP

ULK2

561

Q8IYT8
GYVPPPVATPFSSKS

ZYX

171

Q15942
KSPPVPVPSYPSSGS

ULK1

286

O75385
ISPGSPPYPQSRKLS

TNS2

831

Q63HR2
TPGSSIPPYLSPSQD

ZMIZ1

521

Q9ULJ6
SPPAVTPSTYKGAPS

NACA

1581

E9PAV3