Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	RNA splicing	DDX23 HTATSF1 ZBTB7A TFIP11 ATXN7 SUPT6H SF3B2 CD2BP2	1.54e-06	502	35	8	GO:0008380
GeneOntologyBiologicalProcess	mRNA metabolic process	DDX23 HTATSF1 ZC3H14 ZBTB7A TFIP11 SSB TAF11 SUPT6H SF3B2 CD2BP2	1.91e-06	917	35	10	GO:0016071
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	DDX23 HTATSF1 ZBTB7A TFIP11 SF3B2 CD2BP2	2.78e-05	358	35	6	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	DDX23 HTATSF1 ZBTB7A TFIP11 SF3B2 CD2BP2	2.78e-05	358	35	6	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	DDX23 HTATSF1 ZBTB7A TFIP11 SF3B2 CD2BP2	2.96e-05	362	35	6	GO:0000375
GeneOntologyBiologicalProcess	mRNA processing	DDX23 HTATSF1 ZBTB7A TFIP11 SUPT6H SF3B2 CD2BP2	3.28e-05	551	35	7	GO:0006397
GeneOntologyBiologicalProcess	protein-RNA complex organization	DDX23 HTATSF1 TFIP11 SF3B2 CD2BP2	6.53e-05	254	35	5	GO:0071826
GeneOntologyBiologicalProcess	RNA processing	THUMPD1 DDX23 HTATSF1 ZBTB7A TFIP11 SSB ATXN7 SUPT6H SF3B2 CD2BP2	1.37e-04	1500	35	10	GO:0006396
GeneOntologyCellularComponent	spliceosomal snRNP complex	DDX23 HTATSF1 SF3B2 CD2BP2	1.96e-05	96	35	4	GO:0097525
GeneOntologyCellularComponent	small nuclear ribonucleoprotein complex	DDX23 HTATSF1 SF3B2 CD2BP2	3.01e-05	107	35	4	GO:0030532
GeneOntologyCellularComponent	Sm-like protein family complex	DDX23 HTATSF1 SF3B2 CD2BP2	4.56e-05	119	35	4	GO:0120114
GeneOntologyCellularComponent	nuclear protein-containing complex	DDX23 HTATSF1 ZBTB7A TFIP11 BOD1L1 TAF11 ATXN7 SUPT6H SF3B2 CD2BP2	5.97e-05	1377	35	10	GO:0140513
GeneOntologyCellularComponent	spliceosomal complex	DDX23 HTATSF1 TFIP11 SF3B2	4.44e-04	215	35	4	GO:0005681
GeneOntologyCellularComponent	catalytic step 2 spliceosome	DDX23 TFIP11 SF3B2	5.69e-04	97	35	3	GO:0071013
GeneOntologyCellularComponent	U2-type spliceosomal complex	HTATSF1 TFIP11 SF3B2	5.69e-04	97	35	3	GO:0005684
GeneOntologyCellularComponent	nuclear body	ZC3H14 DAXX TFIP11 RREB1 RAPH1 SF3B2 CD2BP2	6.38e-04	903	35	7	GO:0016604
GeneOntologyCellularComponent	ribonucleoprotein complex	DDX23 HTATSF1 ZC3H14 TFIP11 SSB GTF3C1 SF3B2 CD2BP2	6.53e-04	1194	35	8	GO:1990904
GeneOntologyCellularComponent	nuclear speck	ZC3H14 TFIP11 RREB1 SF3B2 CD2BP2	7.10e-04	431	35	5	GO:0016607
GeneOntologyCellularComponent	U5 snRNP	DDX23 CD2BP2	7.97e-04	25	35	2	GO:0005682
GeneOntologyCellularComponent	U2 snRNP	HTATSF1 SF3B2	1.00e-03	28	35	2	GO:0005686
GeneOntologyCellularComponent	M band	SMTNL1 ANK2	1.23e-03	31	35	2	GO:0031430
GeneOntologyCellularComponent	I band	HRC SMTNL1 ANK2	2.67e-03	166	35	3	GO:0031674
GeneOntologyCellularComponent	U4/U6 x U5 tri-snRNP complex	DDX23 CD2BP2	2.81e-03	47	35	2	GO:0046540
GeneOntologyCellularComponent	spliceosomal tri-snRNP complex	DDX23 CD2BP2	2.93e-03	48	35	2	GO:0097526
GeneOntologyCellularComponent	A band	SMTNL1 ANK2	3.43e-03	52	35	2	GO:0031672
Pathway	BIOCARTA_RNAPOL3_PATHWAY	SSB GTF3C1	5.80e-05	7	24	2	M22046
Pathway	REACTOME_MRNA_SPLICING	DDX23 HTATSF1 TFIP11 SF3B2	4.17e-04	212	24	4	M14033
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	DDX23 HTATSF1 TFIP11 BOD1L1 SSB RAPH1 ANLN SF3B2	3.17e-08	506	35	8	30890647
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	DDX23 ZC3H14 DAXX TFIP11 BOD1L1 GTF3C1 ANLN SUPT6H SF3B2 CD2BP2	3.18e-08	989	35	10	36424410
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	THUMPD1 DDX23 HTATSF1 ZC3H14 BOD1L1 GTF3C1 NCAPH SUPT6H SF3B2 CD2BP2	4.02e-08	1014	35	10	32416067
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZBTB7A DAXX TFIP11 GTF3C1 RREB1 RAPH1 ATXN7 ANLN SF3B2	5.38e-08	774	35	9	15302935
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	DDX23 HTATSF1 TFIP11 GTF3C1 SF3B2 CD2BP2	1.53e-07	244	35	6	29884807
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DDX23 HTATSF1 ZC3H14 ZBTB7A TFIP11 GTF3C1 RREB1 SUPT6H SF3B2 CD2BP2	3.85e-07	1294	35	10	30804502
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	DDX23 HTATSF1 ZC3H14 TFIP11 SSB GTF3C1 SF3B2 CD2BP2	4.33e-07	713	35	8	29802200
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	HTATSF1 SSB SUPT6H SF3B2 CD2BP2	6.16e-07	163	35	5	22113938
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	DAXX BOD1L1 GTF3C1 RREB1 ANLN SF3B2	9.30e-07	332	35	6	32786267
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GABRG1 DNAJC21 DDX23 BOD1L1 TTC24 ANK2 GTF3C1 RAPH1 NCAPH ATXN7	1.03e-06	1442	35	10	35575683
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	TFIP11 SSB GTF3C1 ATXN7 ANLN SF3B2	1.05e-06	339	35	6	30415952
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ZC3H14 TFIP11 BOD1L1 GTF3C1 RAPH1 NCAPH ANLN	1.08e-06	549	35	7	38280479
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DDX23 HTATSF1 TFIP11 THBS1 SSB GTF3C1 ANLN SF3B2 CD2BP2	1.54e-06	1155	35	9	20360068
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HTATSF1 ZC3H14 TFIP11 BOD1L1 ANK2 RAPH1 NCAPH SF3B2	3.25e-06	934	35	8	33916271
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	DDX23 TFIP11 BOD1L1 SUPT6H CD2BP2	5.12e-06	251	35	5	31076518
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	HTATSF1 ZC3H14 TFIP11 SUPT6H SF3B2	5.12e-06	251	35	5	28077445
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	DDX23 ZC3H14 TFIP11 SSB	5.30e-06	114	35	4	31553912
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	DDX23 HTATSF1 SF3B2 CD2BP2	5.49e-06	115	35	4	17332742
Pubmed	The genomic landscape of core-binding factor acute myeloid leukemias.	ZBTB7A TFIP11	5.90e-06	4	35	2	27798625
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	HTATSF1 ZC3H14 BOD1L1 GTF3C1 NCAPH SUPT6H	6.79e-06	469	35	6	27634302
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	BOD1L1 GTF3C1 SUPT6H SF3B2 CD2BP2	7.56e-06	272	35	5	31010829
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DDX23 HTATSF1 TFIP11 SSB RAPH1 NCAPH SUPT6H SF3B2 CD2BP2	8.06e-06	1415	35	9	28515276
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	THUMPD1 HTATSF1 TFIP11 SSB SUPT6H	2.44e-05	347	35	5	16033648
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DNAJC21 ZC3H14 THBS1 GTF3C1 NCAPH ANLN SF3B2 CD2BP2	2.81e-05	1257	35	8	36526897
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	DDX23 HTATSF1 TFIP11 SUPT6H SF3B2 CD2BP2	2.86e-05	605	35	6	28977666
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HTATSF1 ZC3H14 TFIP11 BOD1L1 RREB1 ANLN SF3B2	3.93e-05	954	35	7	36373674
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DDX23 ZC3H14 SSB GTF3C1 SUPT6H SF3B2	4.37e-05	653	35	6	22586326
Pubmed	Structural basis of branch site recognition by the human spliceosome.	HTATSF1 SF3B2	4.40e-05	10	35	2	34822310
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	DDX23 DAXX SSB GTF3C1 NCAPH	4.46e-05	394	35	5	27248496
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DDX23 TFIP11 GTF3C1 NCAPH MAP4K3 ANLN SF3B2 CCDC93	4.73e-05	1353	35	8	29467282
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	HTATSF1 BOD1L1 SSB NCAPH SF3B2	4.74e-05	399	35	5	35987950
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	HTATSF1 GTF3C1 SUPT6H SF3B2	6.99e-05	220	35	4	34091597
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	DDX23 TFIP11 SF3B2	7.27e-05	80	35	3	11991638
Pubmed	Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.	TAF11 ATXN7	8.89e-05	14	35	2	17375202
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DNAJC21 DDX23 HTATSF1 TFIP11 ANK2 SUPT6H SF3B2 GRAMD1A	9.18e-05	1487	35	8	33957083
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DNAJC21 ZC3H14 ZBTB7A DAXX TFIP11 ATXN7 ANLN SUPT6H	9.62e-05	1497	35	8	31527615
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	DDX23 HTATSF1 ZC3H14 NCAPH SUPT6H SF3B2	9.66e-05	754	35	6	35906200
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RAPH1 NCAPH ANLN SF3B2	1.25e-04	256	35	4	33397691
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	TFIP11 ANK2 ANLN SF3B2	1.56e-04	271	35	4	32433965
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ZBTB7A BOD1L1 THBS1 SSB	1.82e-04	282	35	4	23667531
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZC3H14 TFIP11 SSB GTF3C1 SF3B2 CD2BP2	1.82e-04	847	35	6	35850772
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	DDX23 BOD1L1 NCAPH SUPT6H SF3B2 CCDC93	1.82e-04	847	35	6	35235311
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	DDX23 SF3B2 CD2BP2	1.82e-04	109	35	3	12226669
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TFIP11 BOD1L1 SSB SF3B2	1.84e-04	283	35	4	30585729
Pubmed	Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II.	TAF11 ATXN7	1.85e-04	20	35	2	9603525
Pubmed	Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.	HTATSF1 SF3B2	2.04e-04	21	35	2	36797247
Pubmed	Molecular architecture of the human 17S U2 snRNP.	HTATSF1 SF3B2	2.04e-04	21	35	2	32494006
Pubmed	Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling.	GTF3C1 RAPH1	2.04e-04	21	35	2	19725029
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	DDX23 HTATSF1 SF3B2 CD2BP2	2.30e-04	300	35	4	28561026
Pubmed	Structural and functional modularity of the U2 snRNP in pre-mRNA splicing.	HTATSF1 SF3B2	2.68e-04	24	35	2	31744343
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ZC3H14 TFIP11 BOD1L1 GTF3C1	2.70e-04	313	35	4	38270169
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	DAXX GTF3C1 RREB1	2.73e-04	125	35	3	32891193
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ZC3H14 NCAPH SF3B2	3.34e-04	134	35	3	25452129
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DAXX BOD1L1 GTF3C1 RREB1 ANLN	3.38e-04	608	35	5	36089195
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DDX23 TFIP11 GTF3C1 SF3B2	3.74e-04	341	35	4	32971831
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	DNAJC21 SSB ANK2 GTF3C1 SF3B2 CD2BP2	3.79e-04	971	35	6	33306668
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	HTATSF1 GTF3C1 SUPT6H	4.65e-04	150	35	3	28242625
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	DDX23 DAXX SSB SUPT6H SF3B2	4.68e-04	653	35	5	33742100
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	TFIP11 ANK2 CCDC93	4.74e-04	151	35	3	17043677
Pubmed	Human transcription factor protein interaction networks.	ZBTB7A TFIP11 SSB GTF3C1 RREB1 ATXN7 CD2BP2	4.77e-04	1429	35	7	35140242
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	DDX23 HTATSF1 SF3B2	5.02e-04	154	35	3	16055720
Pubmed	RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.	NCAPH SF3B2 CD2BP2	5.21e-04	156	35	3	26170170
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DDX23 SSB GTF3C1 SUPT6H CD2BP2	5.26e-04	670	35	5	22990118
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	DDX23 ANLN SUPT6H SF3B2	6.19e-04	390	35	4	17643375
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	THUMPD1 HTATSF1 GTF3C1 NCAPH ANLN	6.58e-04	704	35	5	29955894
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DDX23 TFIP11 GTF3C1 SUPT6H SF3B2 CD2BP2	6.70e-04	1082	35	6	38697112
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	DDX23 ZC3H14 SSB GTF3C1 RREB1 ANLN	7.41e-04	1103	35	6	34189442
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	DDX23 HTATSF1 TFIP11 SF3B2 CD2BP2	7.41e-04	723	35	5	34133714
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	ZC3H14 ZBTB7A TFIP11 GTF3C1	7.46e-04	410	35	4	26949251
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	DDX23 TFIP11 SSB SF3B2 CD2BP2	7.79e-04	731	35	5	29298432
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TFIP11 BOD1L1 RREB1 ANLN SF3B2	7.89e-04	733	35	5	34672954
Pubmed	The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.	DDX23 TFIP11	8.26e-04	42	35	2	34244791
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	SUPT6H SF3B2	8.66e-04	43	35	2	34672947
Pubmed	Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.	DDX23 SF3B2	8.66e-04	43	35	2	26030138
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DNAJC21 ZC3H14 SSB GTF3C1 CD2BP2	9.22e-04	759	35	5	35915203
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	THUMPD1 HTATSF1 SSB NCAPH SF3B2 CD2BP2	9.33e-04	1153	35	6	29845934
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	DNAJC21 DAXX ANK2	9.38e-04	191	35	3	20195357
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DAXX SSB GTF3C1 SUPT6H	9.70e-04	440	35	4	34244565
Pubmed	Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat.	HTATSF1 TAF11	9.90e-04	46	35	2	8849451
Interaction	SNRPF interactions	DDX23 HTATSF1 ZC3H14 TFIP11 SSB MAP4K3 ANLN SUPT6H SF3B2 CD2BP2	6.91e-10	385	35	10	int:SNRPF
Interaction	SLU7 interactions	DDX23 HTATSF1 TFIP11 ANLN SUPT6H SF3B2 CD2BP2	8.16e-09	156	35	7	int:SLU7
Interaction	SNRPA1 interactions	HTATSF1 ZC3H14 TFIP11 SSB GTF3C1 ANLN SF3B2 CD2BP2	3.65e-08	300	35	8	int:SNRPA1
Interaction	SNRPB interactions	DDX23 HTATSF1 ZC3H14 TFIP11 SSB ANLN SUPT6H SF3B2 CD2BP2	1.75e-07	517	35	9	int:SNRPB
Interaction	TERF2IP interactions	DDX23 HTATSF1 ZC3H14 BOD1L1 GTF3C1 RREB1 ANLN SUPT6H SF3B2	3.04e-07	552	35	9	int:TERF2IP
Interaction	SF3A1 interactions	DDX23 HTATSF1 ZC3H14 TFIP11 RREB1 ANLN SF3B2 CD2BP2	1.13e-06	471	35	8	int:SF3A1
Interaction	NUP50 interactions	HTATSF1 ZC3H14 TFIP11 BOD1L1 SSB NCAPH SUPT6H	1.67e-06	341	35	7	int:NUP50
Interaction	PYHIN1 interactions	HTATSF1 ZC3H14 DAXX TFIP11 RREB1 SUPT6H SF3B2	2.31e-06	358	35	7	int:PYHIN1
Interaction	CD2BP2 interactions	DDX23 HTATSF1 TFIP11 ANLN SF3B2 CD2BP2	2.68e-06	232	35	6	int:CD2BP2
Interaction	SNRPB2 interactions	DDX23 HTATSF1 SSB MAP4K3 SF3B2 CD2BP2	4.62e-06	255	35	6	int:SNRPB2
Interaction	SNRPD2 interactions	DDX23 HTATSF1 TFIP11 SSB ANLN SF3B2 CD2BP2	6.00e-06	414	35	7	int:SNRPD2
Interaction	H2AX interactions	THUMPD1 DDX23 HTATSF1 SSB GTF3C1 ANLN SUPT6H SF3B2	6.25e-06	593	35	8	int:H2AX
Interaction	MEN1 interactions	DDX23 ZC3H14 DAXX TFIP11 BOD1L1 SSB GTF3C1 ANLN SF3B2 CD2BP2	6.57e-06	1029	35	10	int:MEN1
Interaction	SF3A2 interactions	DDX23 HTATSF1 TFIP11 ANLN SF3B2 CD2BP2	6.83e-06	273	35	6	int:SF3A2
Interaction	SNRPC interactions	DDX23 HTATSF1 ZC3H14 TFIP11 SUPT6H SF3B2 CD2BP2	8.93e-06	440	35	7	int:SNRPC
Interaction	PRPF3 interactions	DDX23 HTATSF1 TFIP11 ANLN SF3B2 CD2BP2	9.82e-06	291	35	6	int:PRPF3
Interaction	DHX8 interactions	DDX23 HTATSF1 ZC3H14 TFIP11 ANLN CD2BP2	1.00e-05	292	35	6	int:DHX8
Interaction	SENP3 interactions	DDX23 ZC3H14 DAXX GTF3C1 NCAPH ANLN	1.19e-05	301	35	6	int:SENP3
Interaction	SNRNP200 interactions	DDX23 HTATSF1 TFIP11 BOD1L1 ANLN SF3B2 CD2BP2	1.19e-05	460	35	7	int:SNRNP200
Interaction	PNN interactions	DDX23 ZC3H14 DAXX TFIP11 ANLN CD2BP2	1.21e-05	302	35	6	int:PNN
Interaction	SNRPE interactions	DDX23 HTATSF1 TFIP11 SSB SF3B2 CD2BP2	1.28e-05	305	35	6	int:SNRPE
Interaction	SNRPA interactions	DDX23 ZC3H14 TFIP11 ANLN SUPT6H SF3B2 CD2BP2	1.61e-05	482	35	7	int:SNRPA
Interaction	SNRPN interactions	DDX23 HTATSF1 TFIP11 SF3B2 CD2BP2	1.65e-05	186	35	5	int:SNRPN
Interaction	ACTC1 interactions	DDX23 HTATSF1 TFIP11 BOD1L1 SSB RAPH1 ANLN SF3B2	1.96e-05	694	35	8	int:ACTC1
Interaction	SNRPG interactions	DDX23 HTATSF1 TFIP11 SF3B2 CD2BP2	2.22e-05	198	35	5	int:SNRPG
Interaction	CHD4 interactions	DDX23 HTATSF1 ZBTB7A DAXX TFIP11 NCAPH SUPT6H SF3B2 CD2BP2	2.33e-05	938	35	9	int:CHD4
Interaction	SF3B2 interactions	HTATSF1 DAXX TFIP11 NCAPH ANLN SF3B2 CD2BP2	2.53e-05	517	35	7	int:SF3B2
Interaction	SNRPD1 interactions	DDX23 SSB MAP4K3 ANLN SF3B2 CD2BP2	2.66e-05	347	35	6	int:SNRPD1
Interaction	SRRM1 interactions	DDX23 HTATSF1 ZC3H14 ANLN SF3B2 CD2BP2	2.70e-05	348	35	6	int:SRRM1
Interaction	WBP4 interactions	DDX23 HTATSF1 TFIP11 SF3B2	3.73e-05	109	35	4	int:WBP4
Interaction	PUF60 interactions	DDX23 ZC3H14 SSB ANLN SF3B2 CD2BP2	3.75e-05	369	35	6	int:PUF60
Interaction	COIL interactions	DDX23 HTATSF1 DAXX GTF3C1 RREB1 ANLN SUPT6H	3.84e-05	552	35	7	int:COIL
Interaction	ERCC6 interactions	DDX23 HTATSF1 ANLN SUPT6H SF3B2	4.01e-05	224	35	5	int:ERCC6
Interaction	RSRC1 interactions	DDX23 TFIP11 SSB CD2BP2	4.14e-05	112	35	4	int:RSRC1
Interaction	SFPQ interactions	DNAJC21 DDX23 HTATSF1 TFIP11 ANLN SF3B2 CD2BP2	4.36e-05	563	35	7	int:SFPQ
Interaction	SF3B1 interactions	DDX23 HTATSF1 ZBTB7A TFIP11 ANLN SF3B2 CD2BP2	4.77e-05	571	35	7	int:SF3B1
Interaction	ZCCHC10 interactions	DAXX TFIP11 GTF3C1 TAF11 SF3B2	5.14e-05	236	35	5	int:ZCCHC10
Interaction	PAXBP1 interactions	DDX23 HTATSF1 TFIP11 CD2BP2	5.61e-05	121	35	4	int:PAXBP1
Interaction	SUMO2 interactions	DAXX BOD1L1 GTF3C1 RREB1 ATXN7 ANLN SF3B2	5.92e-05	591	35	7	int:SUMO2
Interaction	SRSF7 interactions	DDX23 HTATSF1 ZC3H14 TFIP11 GTF3C1 ANLN	8.21e-05	425	35	6	int:SRSF7
Interaction	RNPS1 interactions	DDX23 ZC3H14 DAXX GTF3C1 ANLN SUPT6H	8.21e-05	425	35	6	int:RNPS1
Interaction	CWC15 interactions	DDX23 TFIP11 ANLN SF3B2	8.34e-05	134	35	4	int:CWC15
Interaction	TFIP11 interactions	DDX23 DAXX TFIP11 LYSMD1 SF3B2 CD2BP2	8.42e-05	427	35	6	int:TFIP11
Interaction	SUZ12 interactions	DDX23 HTATSF1 ZC3H14 SSB GTF3C1 NCAPH SF3B2	1.02e-04	644	35	7	int:SUZ12
Interaction	ZC3H18 interactions	DDX23 ZC3H14 DAXX TFIP11 SSB ANLN SF3B2 CD2BP2	1.03e-04	877	35	8	int:ZC3H18
Interaction	MKI67 interactions	ZC3H14 ZBTB7A DAXX TFIP11 GTF3C1 NCAPH ANLN	1.06e-04	648	35	7	int:MKI67
Interaction	PRPF19 interactions	TFIP11 SSB NCAPH ANLN SF3B2 CD2BP2	1.12e-04	450	35	6	int:PRPF19
Interaction	MATR3 interactions	DDX23 GTF3C1 RAPH1 NCAPH ATXN7 ANLN SF3B2	1.13e-04	655	35	7	int:MATR3
Interaction	SMC4 interactions	DDX23 ZBTB7A NCAPH ANLN SF3B2	1.17e-04	281	35	5	int:SMC4
Interaction	SSRP1 interactions	DDX23 ZC3H14 DAXX SSB ANLN SUPT6H CD2BP2	1.49e-04	685	35	7	int:SSRP1
Interaction	SRSF4 interactions	DDX23 HTATSF1 ZC3H14 SF3B2 CD2BP2	1.59e-04	300	35	5	int:SRSF4
Interaction	NAT10 interactions	THUMPD1 DDX23 SSB ANLN CD2BP2	1.64e-04	302	35	5	int:NAT10
Interaction	SAP18 interactions	DDX23 ZC3H14 THBS1 GTF3C1 ANLN	1.72e-04	305	35	5	int:SAP18
Interaction	WEE2-AS1 interactions	DDX23 DAXX THBS1 GTF3C1	1.78e-04	163	35	4	int:WEE2-AS1
Interaction	GCFC2 interactions	DDX23 TFIP11 CD2BP2	1.86e-04	64	35	3	int:GCFC2
Interaction	CSNK2A1 interactions	HTATSF1 DAXX SSB ANLN SUPT6H SF3B2 CD2BP2 GRAMD1A	1.87e-04	956	35	8	int:CSNK2A1
Interaction	H3C3 interactions	DAXX BOD1L1 GTF3C1 RREB1 ANLN SUPT6H	1.89e-04	495	35	6	int:H3C3
Interaction	SRSF6 interactions	DDX23 ZC3H14 DAXX SSB ANLN CD2BP2	2.06e-04	503	35	6	int:SRSF6
Interaction	RPS16 interactions	DNAJC21 DDX23 DAXX SSB NCAPH ANLN SF3B2	2.09e-04	724	35	7	int:RPS16
Interaction	H2AC4 interactions	DDX23 DAXX GTF3C1 NCAPH SUPT6H SF3B2	2.13e-04	506	35	6	int:H2AC4
Interaction	PHF5A interactions	DDX23 HTATSF1 SF3B2 CD2BP2	2.13e-04	171	35	4	int:PHF5A
Interaction	NAA40 interactions	HTATSF1 ZC3H14 TFIP11 BOD1L1 ANK2 RAPH1 NCAPH SF3B2	2.18e-04	978	35	8	int:NAA40
Interaction	DHX16 interactions	DDX23 TFIP11 ANLN SF3B2	2.23e-04	173	35	4	int:DHX16
Interaction	SNRNP70 interactions	DDX23 HTATSF1 ZC3H14 TFIP11 SSB GTF3C1 SF3B2 CD2BP2	2.27e-04	984	35	8	int:SNRNP70
Interaction	NOLC1 interactions	DDX23 HTATSF1 DAXX GTF3C1 ANLN	2.31e-04	325	35	5	int:NOLC1
Interaction	ARGLU1 interactions	DDX23 ZC3H14 SSB ANLN	2.38e-04	176	35	4	int:ARGLU1
Interaction	PDCD4 interactions	DAXX SSB NCAPH ANLN	2.38e-04	176	35	4	int:PDCD4
Interaction	CRNKL1 interactions	TFIP11 ANK2 ANLN SF3B2	2.43e-04	177	35	4	int:CRNKL1
Interaction	KPNA2 interactions	DDX23 BOD1L1 SSB NCAPH ANLN SF3B2	2.44e-04	519	35	6	int:KPNA2
Interaction	PRP4K interactions	DDX23 HTATSF1 TFIP11 SF3B2 CD2BP2	2.44e-04	329	35	5	int:PRP4K
Interaction	TOP2A interactions	DNAJC21 DDX23 DAXX NCAPH ANLN SF3B2	2.46e-04	520	35	6	int:TOP2A
Interaction	SPEN interactions	HTATSF1 DAXX TFIP11 ANLN	2.49e-04	178	35	4	int:SPEN
Interaction	SNW1 interactions	DDX23 DAXX TFIP11 NCAPH ANLN SF3B2 CD2BP2	2.54e-04	747	35	7	int:SNW1
Interaction	H3-3A interactions	DDX23 DAXX BOD1L1 GTF3C1 RREB1 ANLN SF3B2	2.58e-04	749	35	7	int:H3-3A
Interaction	CHD3 interactions	DDX23 HTATSF1 ZBTB7A TFIP11 SUPT6H SF3B2 CD2BP2	2.75e-04	757	35	7	int:CHD3
Interaction	SF3A3 interactions	DDX23 TFIP11 ANLN SF3B2 CD2BP2	2.84e-04	340	35	5	int:SF3A3
Interaction	TRIR interactions	HTATSF1 TFIP11 SF3B2	2.86e-04	74	35	3	int:TRIR
Interaction	PRPF8 interactions	DDX23 TFIP11 BOD1L1 RREB1 ANLN SF3B2 CD2BP2	3.20e-04	776	35	7	int:PRPF8
Interaction	LSM2 interactions	DDX23 SSB SF3B2 CD2BP2	3.25e-04	191	35	4	int:LSM2
Interaction	RBM39 interactions	DDX23 ZC3H14 ZBTB7A TFIP11 SSB ANLN SF3B2 CD2BP2	3.35e-04	1042	35	8	int:RBM39
Interaction	LYSMD1 interactions	TFIP11 LYSMD1	3.46e-04	16	35	2	int:LYSMD1
Interaction	NCL interactions	DDX23 HTATSF1 DAXX SSB GTF3C1 ANLN SUPT6H	3.79e-04	798	35	7	int:NCL
Interaction	SDC4 interactions	DAXX GTF3C1 ANLN	3.87e-04	82	35	3	int:SDC4
Interaction	USP39 interactions	DDX23 GTF3C1 ANLN CD2BP2	3.95e-04	201	35	4	int:USP39
Interaction	DOT1L interactions	ZC3H14 DAXX TFIP11 SSB GTF3C1 SF3B2 CD2BP2	4.05e-04	807	35	7	int:DOT1L
Interaction	SRSF11 interactions	DDX23 ZC3H14 SF3B2 CD2BP2	4.10e-04	203	35	4	int:SRSF11
Interaction	PRPF31 interactions	DDX23 TFIP11 SSB ANLN CD2BP2	4.40e-04	374	35	5	int:PRPF31
Interaction	PALM interactions	PTPRG ANLN CD2BP2	4.60e-04	87	35	3	int:PALM
Interaction	THOC1 interactions	ZC3H14 TFIP11 ANLN SF3B2	4.66e-04	210	35	4	int:THOC1
Interaction	YAP1 interactions	THUMPD1 ZC3H14 TFIP11 BOD1L1 THBS1 GTF3C1 NCAPH SF3B2	4.68e-04	1095	35	8	int:YAP1
Interaction	SNRPD3 interactions	DDX23 SSB ANLN SF3B2 CD2BP2	4.73e-04	380	35	5	int:SNRPD3
Interaction	IK interactions	DDX23 HTATSF1 TFIP11 ANLN	5.09e-04	215	35	4	int:IK
Interaction	THOC2 interactions	DDX23 ZC3H14 TFIP11 ANLN	5.45e-04	219	35	4	int:THOC2
Interaction	RPL23A interactions	DAXX TFIP11 SSB NCAPH ANLN SF3B2	5.57e-04	606	35	6	int:RPL23A
Interaction	THUMPD3 interactions	THUMPD1 ZC3H14 SSB	5.77e-04	94	35	3	int:THUMPD3
Interaction	TMA16 interactions	MAP4K3 ANLN SUPT6H	5.95e-04	95	35	3	int:TMA16
Interaction	DDX46 interactions	DDX23 ANLN SF3B2 CD2BP2	6.24e-04	227	35	4	int:DDX46
Interaction	EFTUD2 interactions	DDX23 HTATSF1 TFIP11 SSB RAPH1 NCAPH ANLN SF3B2 CD2BP2	6.39e-04	1449	35	9	int:EFTUD2
Interaction	CIT interactions	DDX23 ZC3H14 TFIP11 BOD1L1 SSB RREB1 ANLN SUPT6H SF3B2	6.42e-04	1450	35	9	int:CIT
Interaction	SUPT5H interactions	DDX23 HTATSF1 GTF3C1 ANLN SUPT6H	6.53e-04	408	35	5	int:SUPT5H
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	THUMPD1 GTF3C1 APOBR	3.10e-04	172	35	3	chr16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr3p14	PTPRG ATXN7	5.14e-03	140	35	2	chr3p14
Drug	Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; HL60; HG-U133A	THUMPD1 ZC3H14 TFIP11 ATXN7 CD2BP2	1.18e-05	196	35	5	2046_UP
Drug	Loxapine succinate [27833-64-3]; Up 200; 9uM; HL60; HG-U133A	ZBTB7A TFIP11 TAF11 ATXN7 CD2BP2	1.30e-05	200	35	5	2016_UP
Disease	intellectual disability (implicated_via_orthology)	ZC3H14 BOD1L1 ANK2	6.74e-05	75	31	3	DOID:1059 (implicated_via_orthology)
Disease	visceral adipose tissue measurement	ZC3H14 ZBTB7A DAXX PTPRG	1.55e-03	481	31	4	EFO_0004765
Disease	pulse pressure measurement	ZBTB7A ANK2 RREB1 RAPH1 ATXN7 SUPT6H	2.91e-03	1392	31	6	EFO_0005763
Disease	Glioblastoma	ZBTB7A DAXX	3.13e-03	79	31	2	C0017636
Disease	calcium measurement	RREB1 NCAPH MAP4K3 GRAMD1A	4.05e-03	628	31	4	EFO_0004838
Disease	Malignant neoplasm of breast	DNAJC21 BOD1L1 THBS1 ANK2 RAPH1	4.89e-03	1074	31	5	C0006142
Disease	cortical thickness, neuroimaging measurement	THBS1 RREB1	5.97e-03	110	31	2	EFO_0004346, EFO_0004840

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKDEKSESEDGEREH	PTPRG	581	P23470
GEREHEEDGEKDSEK	PTPRG	591	P23470
DEEEEAAAGKDGDKS	DAXX	481	Q9UER7
DADHGAEEDKEEQVD	GRAMD1A	286	Q96CP6
HGAEEDSDKEDQDLD	RAPH1	11	Q70E73
HECAEEDDSENGEKK	ANK2	2566	Q01484
HLEDDEGDDDESKHS	MAP4K3	411	Q8IVH8
GLDSEEEKDGEEKVH	LYSMD1	96	Q96S90
KTKFASDDEHDEHDE	SSB	361	P05455
ENHGEAKNDEKGVED	SLC24A1	836	O60721
DEEHGKGSLEEAEAE	ANLN	746	Q9NQW6
DRDSKKDEEDEHGDK	DDX23	121	Q9BUQ8
HELKDEEDGKDSDEA	DNAJC21	291	Q5F1R6
EEEDEDRKNKGHQAA	ERMN	141	Q8TAM6
EGDDKEESVEKLDCH	ATXN7	496	O15265
LEAADKKAEEGDADE	HTATSF1	656	O43719
DDKDGKEVDSSHEKA	BOD1L1	1041	Q8NFC6
FKGKHSLDSDEEEDD	CD2BP2	41	O95400
KADAHEEDELRAAEE	CCDC93	236	Q567U6
HLGNCVDKADDEDDE	GABRG1	31	Q8N1C3
DGDADVDLKEAAAEE	TAF11	41	Q15544
KEKEEDPGSHEEDDE	HRC	486	P23327
DSKEKEEAAAGEHAG	APOBR	791	Q0VD83
KEADAEANHREAGKE	NCAPH	661	Q15003
DEEEYGKEEHEKEAI	SUPT6H	131	Q7KZ85
KKGFEEEHKDSDDDS	SF3B2	421	Q13435
DKDGKGDACDHDDDN	THBS1	886	P07996
EDEEFEEGHQKKKEE	TTC24	456	A2A3L6
HGAKEEADAKEEAED	SMTNL1	226	A8MU46
HGKDSDKEERGEEDS	RREB1	1571	Q92766
LKEFKRNDHDDDEDE	GTF3C1	336	Q12789
KKFNHDGEEEEEDDD	ZC3H14	306	Q6PJT7
KKGAAEEAELEDSDD	TFIP11	86	Q9UBB9
EDDDAEAALKKEVGD	THUMPD1	91	Q9NXG2
RNGQEKHFKDEDEDE	ZBTB7A	531	O95365
HEFKEGKDELSEQDE	VTCN1	81	Q7Z7D3