Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesshypothalamus development

NDNF RAX PITX2

3.90e-0531443GO:0021854
GeneOntologyCellularComponentcochlear hair cell ribbon synapse

BSN OTOF

7.07e-056462GO:0098683
DomainZnF_U1

ZFHX2 RBM20 MATR3

4.27e-0529443SM00451
DomainZnf_U1

ZFHX2 RBM20 MATR3

4.27e-0529443IPR003604
DomainZnf_C2H2_matrin

RBM20 MATR3

3.53e-0412442IPR000690
DomainCarboxyPept_regulatory_dom

CPXM2 AEBP1

4.16e-0413442IPR014766
Domain-

CPXM2 AEBP1

4.16e-04134422.60.40.1120
DomainOAR

RAX PITX2

5.59e-0415442PF03826
DomainOAR

RAX PITX2

6.37e-0416442PS50803
DomainOAR_dom

RAX PITX2

6.37e-0416442IPR003654
DomainCarboxyPept-like_regulatory

CPXM2 AEBP1

7.21e-0417442IPR008969
DomainZn_pept

CPXM2 AEBP1

8.10e-0418442SM00631
DomainZF_MATRIN

RBM20 MATR3

8.10e-0418442PS50171
DomainCARBOXYPEPT_ZN_1

CPXM2 AEBP1

1.00e-0320442PS00132
DomainFA58C

CPXM2 AEBP1

1.11e-0321442SM00231
DomainFA58C_3

CPXM2 AEBP1

1.11e-0321442PS50022
DomainFA58C_1

CPXM2 AEBP1

1.11e-0321442PS01285
DomainFA58C_2

CPXM2 AEBP1

1.11e-0321442PS01286
DomainPeptidase_M14

CPXM2 AEBP1

1.33e-0323442PF00246
DomainPeptidase_M14

CPXM2 AEBP1

1.33e-0323442IPR000834
DomainF5_F8_type_C

CPXM2 AEBP1

1.45e-0324442PF00754
DomainFA58C

CPXM2 AEBP1

1.45e-0324442IPR000421
Pubmed

A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a.

TFAP2A PITX2

1.71e-06246227866707
Pubmed

Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

TFAP2A RAX PITX2

1.26e-053446320301552
Pubmed

Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium.

TFAP2A PITX2

1.71e-05546216836994
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SCAMP3 BCAR1 TMEM92 BSN AEBP1 NFATC4

2.13e-0543046635044719
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

ZFHX2 IRF4 TFAP2A RAX PITX2

2.53e-0526346520932939
Pubmed

Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas.

DOK1 BCAR1

2.56e-05646211278335
Pubmed

Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation.

TFAP2A PITX2

3.58e-05746223307821
Pubmed

Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors.

VOPP1 TMEM92

3.58e-05746222120523
Pubmed

Eye formation in the absence of retina.

RAX PITX2

6.12e-05946218675797
Pubmed

Acquisition of neural fate by combination of BMP blockade and chromatin modification.

TFAP2A RAX

6.12e-05946237771660
Pubmed

Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling.

TFAP2A PITX2

6.12e-05946215070745
Pubmed

Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation.

TFAP2A PITX2

6.12e-05946239052671
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

LAPTM4A ADCY4 NFATC4 AFAP1L1

6.51e-0516346435364055
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SCRT2 IRF4 NFATC4 TFAP2A RAX PITX2

7.85e-0554446628473536
Pubmed

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway.

TFAP2A PITX2

9.34e-051146215475956
Pubmed

AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis.

TFAP2A PITX2

1.12e-041246220150232
Pubmed

Pitx2-mediated cardiac outflow tract remodeling.

TFAP2A PITX2

1.12e-041246223361844
Pubmed

Lens induction requires attenuation of ERK signaling by Nf1.

TFAP2A PITX2

1.32e-041346221233129
Pubmed

Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1.

TFAP2A RAX

1.78e-041546236924502
Pubmed

GATA3 is essential for separating patterning domains during facial morphogenesis.

TFAP2A PITX2

1.78e-041546234383890
Pubmed

A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.

BSN CPXM2

2.03e-041646225082827
Pubmed

AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.

TFAP2A PITX2

2.03e-041646226968737
Pubmed

Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis.

TFAP2A PITX2

2.03e-041646225242040
Pubmed

Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.

TFAP2A PITX2

2.30e-041746218832393
Pubmed

Multiple essential roles for primary cilia in heart development.

TFAP2A PITX2

2.30e-041746223351706
Pubmed

Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences.

NDNF TFAP2A

2.58e-041846220016822
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

CPXM2 AEBP1 LOXL1

3.30e-0410146320551380
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

PARP4 TFAP2A RBM20 RC3H1 MATR3

3.37e-0445746532344865
Pubmed

Global landscape of HIV-human protein complexes.

DOK1 PARP4 SCAMP3 VIRMA MATR3

3.37e-0445746522190034
Pubmed

The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus.

BSN PITX2

3.89e-042246237532091
Pubmed

Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis.

TFAP2A PITX2

4.25e-042346223112163
Pubmed

Cascade diversification directs generation of neuronal diversity in the hypothalamus.

RAX PITX2

4.64e-042446233887179
Pubmed

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.

BSN TFAP2A

4.64e-042446235179492
Pubmed

Tbx3 is required for outflow tract development.

TFAP2A PITX2

4.64e-042446218723448
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PARP4 UBN2 REXO1 RC3H1 GNPTAB

4.76e-0449346515368895
Pubmed

Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.

SCAMP3 BSN

5.04e-042546215935055
Pubmed

The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.

TFAP2A RAX

5.45e-042646227697904
Pubmed

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.

VIRMA RC3H1

5.88e-042746235709258
Pubmed

Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.

RAX PITX2

5.88e-042746230063881
Pubmed

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

TFAP2A RAX

6.33e-042846223595746
Pubmed

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi.

TFAP2A PITX2

6.33e-042846238344749
Pubmed

Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.

TFAP2A RAX

6.79e-042946219474320
Pubmed

Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.

RAX PITX2

7.27e-043046223426374
Pubmed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

DOK1 BCAR1

8.28e-043246222974441
Pubmed

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.

BSN PITX2

9.35e-043446225915474
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

IRF4 AEBP1 NFATC4 TFAP2A RAX PITX2

1.00e-0387746620211142
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

TIMM50 CHERP NFATC4 MATR3 PITX2

1.01e-0358346529844126
Pubmed

Gene expression in pharyngeal arch 1 during human embryonic development.

MATR3 PITX2

1.05e-033646215703188
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

UBN2 RC3H1 PITX2

1.08e-0315246338360978
Pubmed

A census of human transcription factors: function, expression and evolution.

ZFHX2 IRF4 NFATC4 TFAP2A RAX PITX2

1.20e-0390846619274049
Pubmed

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.

TIMM50 CNN2 MATR3

1.23e-0315946331332168
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

BCAR1 NFATC4 CNN2 ABCC10 MATR3 PITX2

1.32e-0392546628986522
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SCAF1 AMER1 OTOF MATR3

1.32e-0336146426167880
GeneFamilyPRD class homeoboxes and pseudogenes

RAX PITX2

6.57e-0392242521
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

C11orf91 TMEM92 RBM20 MATR3 AFAP1L1

6.61e-071574752c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAPTM4A AEBP1 TFAP2A LOXL1 CNN2

1.01e-061714752e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAPTM4A AEBP1 TFAP2A LOXL1 CNN2

1.01e-06171475e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

SCRT2 ZFHX2 LRRC43 RSPH4A

1.53e-05142474369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOK1 ADCY4 LRRC43 AFAP1L1

2.10e-05154474212c340a096a3a9669d1aebd61c045cf1402a868
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFHX2 CPXM2 OTOF PITX2

2.82e-051664749a341dc7b756252caeaac1e934384911c880a634
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFHX2 CPXM2 OTOF PITX2

2.82e-05166474390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPXM2 OTOF RBM20 PITX2

3.09e-05170474da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPXM2 OTOF RBM20 PITX2

3.09e-05170474cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 TFAP2A LOXL1 CNN2

3.62e-05177474599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 ARRDC2 RSPH4A AFAP1L1

3.70e-051784744ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 ARRDC2 RSPH4A AFAP1L1

3.70e-05178474c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

3.78e-0517947435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

3.78e-05179474ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDNF CPXM2 AEBP1 LOXL1

3.95e-05181474269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDNF CPXM2 AEBP1 LOXL1

3.95e-05181474cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDNF CPXM2 AEBP1 LOXL1

3.95e-05181474c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AEBP1 NFATC4 TFAP2A LOXL1

4.21e-05184474235890e8b424f4386b6ea52d173d20a00898df73
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.30e-051854743be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.30e-05185474fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.30e-05185474c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPXM2 AEBP1 RBM20 LOXL1

4.39e-051864747c1807fca590cdccf7f5734460bac228d33964ca
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.39e-051864749d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF4 ERN1 OTOF GNPTAB

4.48e-05187474d17352f769c3c66601b65d060626eecff41b0482
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IRF4 VOPP1 BCAR1 RAX

4.58e-051884748cf135da4d1d2500755d2809d60b41509af9fa8b
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LAPTM4A ADCY4 NFATC4 CNN2

4.67e-05189474ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellwk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.77e-05190474279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCellwk_08-11-Endothelial-Lymph_endothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADCY4 ARRDC2 RSPH4A AFAP1L1

4.77e-05190474d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 BSN AFAP1L1

4.87e-05191474dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAPTM4A CPXM2 AEBP1 LOXL1

5.17e-05194474889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.49e-051974744e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell(2)_Fibroblasts-(22)_Fibro-3|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

CPXM2 AEBP1 LOXL1 CNN2

5.49e-05197474d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.60e-05198474307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAPTM4A AEBP1 LOXL1 PITX2

5.60e-05198474d4f74320ea6c1a7e568ee5bc48bb66cb45e1004d
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.60e-05198474122215d9288533ad03562cf777e846504863df9a
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.71e-0519947441f046646fff65b7e51b63d3204f76ef32054781
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

AEBP1 NFATC4 LOXL1 CNN2

5.71e-05199474fcbb3a9c0f4c5b4c1f09db24b9f50cc1166fa43b
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.71e-05199474ef7f7f7c861827574b120f48cf4052c563929081
ToppCell10x5'v1-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.82e-052004742488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell10x5'v1-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 BCAR1 RSPH4A AFAP1L1

5.82e-05200474e786544cf6f891550c4be55ebb4928c92297b504
ToppCellPBMC-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

ADCY4 OTOF MATR3

8.61e-05814736d1e524f000b71c935359afc801a1d31f218fec8
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn-Endothelial_Tip.Dcn.Nenf_(Nenf)|Thalamus / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

2.37e-041144737be16e7f7b9c9dbd68933ace3b7f8f661bed41a7
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn|Thalamus / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

2.37e-04114473f4bdfc47418d22a49e0c4a6c3bd0663e15fb53bb
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

2.82e-041214735035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

2.82e-04121473c96115bd33455296378a257583b49442d00b39ca
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

AMER1 TMEM92 MATR3

2.89e-04122473a2f343962069253a08faa80fd70723b8488a99ec
ToppCellHippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

C11orf91 MFRP TENT5D

3.25e-04127473ca77f85502dd66f3cb4b15cf80f755104ca1e6ff
ToppCellHippocampus-Macroglia-CSF_related-CHOROID_PLEXUS|Hippocampus / BrainAtlas - Mouse McCarroll V32

C11orf91 MFRP TENT5D

3.25e-0412747325d0b28c9df2d10fbcdb0aca47b75bf5c7c9c430
ToppCellHippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

C11orf91 MFRP TENT5D

3.25e-04127473b27d5141e661a4c6924aa6d7c5b046f9ae49955d
ToppCellHippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)|Hippocampus / BrainAtlas - Mouse McCarroll V32

C11orf91 MFRP TENT5D

3.25e-04127473352d44233a93c926aeb7c5fad49965fd82b873ca
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

3.40e-04129473856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Thalamus / BrainAtlas - Mouse McCarroll V32

C11orf91 ADCY4 FAM217A

3.72e-0413347329b0c2c682c6b97823e7d8d8ba1f5114044b30ba
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

CPXM2 NFATC4 TFAP2A

3.81e-04134473b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCellCerebellum-Macroglia-CSF_related|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC43 MFRP RSPH4A

4.06e-04137473f004199b654143e9e766e5c5f56858089e98cf5f
ToppCellCerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC43 MFRP RSPH4A

4.06e-041374736a5599af9d0ee1be6cac17af09aa4cd50774c683
ToppCellCerebellum-Macroglia-CSF_related-CHOROID_PLEXUS|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC43 MFRP RSPH4A

4.06e-04137473ce7c57dad201bd2164fc8b1172aca709f3f7def2
ToppCellCerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC43 MFRP RSPH4A

4.06e-0413747301cbc9082e10ef51a1763a8b2d708eea0434490f
ToppCellCerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC43 MFRP RSPH4A

4.06e-04137473a22730b6f78b66bb3c46155af37c34e554672dee
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TOP1MT RSPH4A REXO1

5.39e-041514732dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TOP1MT RSPH4A REXO1

5.39e-0415147322afd8201eff8471da3456be065f2790de5e4bfe
ToppCellAdult-Epithelial-basal_cell-D175|Adult / Lineage, Cell type, age group and donor

CPXM2 TFAP2A LOXL1

5.60e-041534739ee3e7f3f19a2474283c1c79045269686f35a541
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AEBP1 TFAP2A LOXL1

5.71e-0415447365dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOK1 CPXM2 LOXL1

5.82e-0415547393f21b09f6f7755991d67886361b1c42a50fbbfc
ToppCellCOVID-19-kidney-Plasma|COVID-19 / Disease (COVID-19 only), tissue and cell type

IRF4 VOPP1 ERN1

6.38e-04160473f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF4 VOPP1 ERN1

6.61e-04162473ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF4 VOPP1 ERN1

6.61e-041624738ed9149ff53b285591354057055d072b203a47c8
ToppCell5'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CPXM2 RAX PITX2

6.61e-04162473472194eccc29c905010e2d8faa67c1a07d5e7118
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF1 VOPP1 GNPTAB

6.61e-0416247375df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF4 VOPP1 ERN1

6.61e-041624737a05b05a33e1309fb5c0a8171db105ae68491815
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF4 VOPP1 ERN1

6.61e-041624739e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF4 ERN1 ABCC10

6.73e-041634735efecdd8a069a822bc9d35b407092925a865e629
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF4 ERN1 ABCC10

6.73e-041634730d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VOPP1 BSN CNN2

6.85e-04164473dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF4 ERN1 ABCC10

6.85e-04164473b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell367C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IRF4 ERN1 AEBP1

6.85e-0416447395b800c78871354c859abaa832d778786ef7bcc0
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF4 ERN1 ABCC10

6.85e-04164473a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 BCAR1 AFAP1L1

6.85e-041644735ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VOPP1 BSN CNN2

6.85e-04164473f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

6.98e-04165473570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CPXM2 TFAP2A LOXL1

6.98e-041654732026a9a07f4d314cc05c167e491312b373468e46
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRF4 VOPP1 ERN1

6.98e-0416547379c6ad394266ff092029375883660028e944a3c8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MFRP RAX PITX2

6.98e-04165473e460e03992781073cd836a655f15dda3157cea55
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

AMER1 TMEM92 MATR3

7.10e-04166473f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IRF4 ERN1 CPXM2

7.10e-04166473c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX2 VOPP1 LRRC43

7.10e-04166473da10d0be6b616199d49dd922591c2901f9681583
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AEBP1 TFAP2A LOXL1

7.22e-04167473805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

IRF4 CHERP ERN1

7.22e-041674731e2fc1637769405a61f4c7e44945712a1888a299
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AEBP1 TFAP2A LOXL1

7.22e-0416747331cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AEBP1 TFAP2A LOXL1

7.22e-041674733acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

AEBP1 TFAP2A LOXL1

7.35e-0416847326aa96b2b547d11941cb803995ea3d302ee0518c
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 TFAP2A LOXL1

7.35e-041684739930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPXM2 AEBP1 LOXL1

7.35e-04168473d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellHealthy_Control-Lymphoid-pDC|Healthy_Control / Condition, Lineage, Cell class and cell subclass

IRF4 ERN1 AEBP1

7.48e-04169473a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCellHealthy_Control-Lymphoid-pDC-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

IRF4 ERN1 AEBP1

7.48e-04169473338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDNF ARRDC2 NFATC4

7.61e-04170473054360a3b05f5e41221c98b122d241b1affad26a
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

IRF4 ERN1 AEBP1

7.61e-04170473fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDNF ARRDC2 NFATC4

7.61e-04170473f0b0d2d0402de3ed7322284a599646db43475761
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BSN TFAP2A CNN2

7.61e-04170473bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

IRF4 VOPP1 ERN1

7.74e-04171473a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

IRF4 ERN1 AEBP1

7.74e-041714731f8e66073088fc1969782e443bf00f8c1877ea91
DiseaseAnophthalmia-microphthalmia syndrome

TFAP2A RAX PITX2

4.62e-0621463cv:C5680330
DiseaseDeafness

RSPH4A OTOF

6.97e-0425462C0011053
Diseaselymphocyte measurement

IRF4 ERN1 RBM20

8.14e-04117463EFO_0803546

Protein segments in the cluster

PeptideGeneStartEntry
VYDVPPPAPDLYDVP

BCAR1

361

P56945
YYFGPPPPQKPDAER

AEBP1

316

Q8IUX7
ADFQPPYFPPPYQPI

TFAP2A

51

P05549
PRRAYPTYSPPEDPE

AMER1

741

Q5JTC6
SPRPPPSEDLFYETY

ADCY4

6

Q8NFM4
RYRPPPLYSEEDPNP

ARRDC2

381

Q8TBH0
YYARPEPELETFSPP

CPXM2

46

Q8N436
VYYQDPRGAAPPFEP

RC3H1

591

Q5TC82
PPHNQPYELYDPEEP

RBM20

341

Q5T481
PRGFFSSPNYPDPYP

MFRP

151

Q9BY79
NPQAYYSPDPPAEPS

ABCC10

581

Q5T3U5
DFDEFIPPLPPPPYY

FAM189A1

236

O60320
PDEYRIGPYQPNVPV

MATR3

776

P43243
IPPTQESYYDPNLPP

GNPTAB

1071

Q3T906
YVPDQPHPEIPYQCP

IRF4

181

Q15306
PEIAVYPAFEAPPQY

LAPTM4A

196

Q15012
EELPEYPPQGFYPAP

LOXL1

241

Q08397
FYGPRDPEPPEPPTY

BSN

1941

Q9UPA5
FYSYEPPSENPPPET

PDCD2

106

Q16342
TPESDQPYPELPYDP

NDNF

166

Q8TB73
NYDPYKPLDITPPPD

PARP4

91

Q9UKK3
PYNPATDDYAVPPPR

DOK1

401

Q99704
PFERPPYPHRFDYPQ

CHERP

561

Q8IWX8
LFQPYYFHEPPEPQP

ERN1

956

O75460
EPNEVFPYPDFLPPP

FAM217A

241

Q8IXS0
YNPFETREPPPAYEP

SCAMP3

41

O14828
DPEPRPEGPFITYNY

LRRC43

326

Q8N309
DEAYCPPRFPPQLEY

OTOF

1061

Q9HC10
PPVEETVFYPSPYPI

PARL

81

Q9H300
NYTPPVPPPVYQEYP

RSPH4A

656

Q5TD94
VPPPVYQEYPSGPEI

RSPH4A

661

Q5TD94
YDPYNPELPKPPAQR

REXO1

56

Q8N1G1
PAYPPAAPEEYSDPE

SCRT2

71

Q9NQ03
TDMDFSPPRPPYPSY

NFATC4

711

Q14934
YPIYVIPEPPPVSFQ

TENT5D

361

Q8NEK8
ACPYAPPTPPYVYRD

PITX2

261

Q99697
PAPEYEAPRPYCPKE

RAX

91

Q9Y2V3
PLPNKPPPEDYYEEA

AFAP1L1

116

Q8TED9
PPPEDYYEEALPLGP

AFAP1L1

121

Q8TED9
PDPGEVPEYPPYYQE

CNN2

291

Q99439
PQEPYGDYRPPALTP

C11orf53

61

Q8IXP5
IPYEPLRFFYSPPPG

C11orf91

101

Q3C1V1
PPPPYSFRPEEYTGD

TMEM92

136

Q6UXU6
YPPPLIEEPAFNVSY

VOPP1

86

Q96AW1
PDPLQEPYYQPPYTL

TIMM50

136

Q3ZCQ8
EYPGPEREPEYPREP

UBN2

21

Q6ZU65
DPSDPPQPYRLADDY

ZFHX2

411

Q9C0A1
PQPYRLADDYTPAPA

ZFHX2

416

Q9C0A1
EAYSPPPAPEQKYDP

SCAF1

236

Q9H7N4
PYFAPPYEPLPDGVR

TOP1MT

61

Q969P6
SPPLYEEYRPPPLDS

SMIM44

16

A0A286YF18
GPPERDDPYPVLFRY

VIRMA

661

Q69YN4