Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRR2 CHRNA6 CHRNB3

1.47e-0457363GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRR2 CHRNA6 CHRNB3

1.72e-0460363GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRR2 CHRNA6 CHRNB3

2.18e-0465363GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRR2 CHRNA6 CHRNB3

2.18e-0465363GO:0022824
GeneOntologyMolecularFunctiongated channel activity

ANO4 GABRR2 CHRNA6 TMC2 CHRNB3

3.13e-04334365GO:0022836
GeneOntologyMolecularFunctionchannel activity

ANO4 GABRR2 CHRNA6 PANX2 TMC2 CHRNB3

3.20e-04525366GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO4 GABRR2 CHRNA6 PANX2 TMC2 CHRNB3

3.23e-04526366GO:0022803
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRR2 CHRNA6 CHRNB3

3.32e-0475363GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRR2 CHRNA6 CHRNB3

3.59e-0477363GO:0005230
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ANO4 GABRR2 CHRNA6 CHRNB3

3.91e-04193364GO:0015276
GeneOntologyMolecularFunctionacetylcholine-gated monoatomic cation-selective channel activity

CHRNA6 CHRNB3

4.23e-0417362GO:0022848
GeneOntologyMolecularFunctionligand-gated channel activity

ANO4 GABRR2 CHRNA6 CHRNB3

4.23e-04197364GO:0022834
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRR2 CHRNA6 CHRNB3

7.72e-04100363GO:0030594
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRNA6 CHRNB3

7.81e-0423362GO:0015464
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO4 GABRR2 CHRNA6 ABCA4 PANX2 ATP7B TMC2 CHRNB3

9.95e-041180368GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO4 GABRR2 CHRNA6 TMC2 CHRNB3

1.31e-03459365GO:0005216
GeneOntologyMolecularFunctiontransporter activity

ANO4 GABRR2 CHRNA6 ABCA4 PANX2 ATP7B TMC2 CHRNB3

1.76e-031289368GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO4 GABRR2 CHRNA6 ATP7B TMC2 CHRNB3

2.71e-03793366GO:0015075
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

CHRNA6 CHRNB3

2.72e-0343362GO:0005231
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

ANO4 GABRR2

3.67e-0350362GO:0099095
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO4 ABCA4

3.81e-0351362GO:0140303
GeneOntologyMolecularFunctionMHC protein binding

MARCHF1 MARCHF8

4.90e-0358362GO:0042287
GeneOntologyCellularComponentacetylcholine-gated channel complex

CHRNA6 CHRNB3

4.34e-0418362GO:0005892
GeneOntologyCellularComponentdopaminergic synapse

CHRNA6 CHRNB3

6.52e-0422362GO:0098691
DomainTeashirt_fam

TSHZ3 TSHZ2

1.08e-053362IPR027008
DomainNeurotransmitter_ion_chnl_CS

GABRR2 CHRNA6 CHRNB3

8.83e-0545363IPR018000
DomainNeur_chan_memb

GABRR2 CHRNA6 CHRNB3

9.43e-0546363PF02932
DomainMARCH-like

MARCHF1 MARCHF8

1.00e-048362IPR033275
DomainNeur_chan_LBD

GABRR2 CHRNA6 CHRNB3

1.01e-0447363PF02931
DomainNeur_channel

GABRR2 CHRNA6 CHRNB3

1.01e-0447363IPR006201
DomainNeur_chan_lig-bd

GABRR2 CHRNA6 CHRNB3

1.01e-0447363IPR006202
DomainNEUROTR_ION_CHANNEL

GABRR2 CHRNA6 CHRNB3

1.01e-0447363PS00236
DomainNeurotrans-gated_channel_TM

GABRR2 CHRNA6 CHRNB3

1.01e-0447363IPR006029
Domain-

GABRR2 CHRNA6 CHRNB3

1.01e-04473632.70.170.10
DomainRINGv

MARCHF1 MARCHF8

1.97e-0411362PF12906
DomainZF_RING_CH

MARCHF1 MARCHF8

1.97e-0411362PS51292
DomainRhoGAP

ARHGAP25 TAGAP SYDE2

2.30e-0462363SM00324
DomainRhoGAP

ARHGAP25 TAGAP SYDE2

2.41e-0463363PF00620
DomainRHOGAP

ARHGAP25 TAGAP SYDE2

2.53e-0464363PS50238
DomainRhoGAP_dom

ARHGAP25 TAGAP SYDE2

2.53e-0464363IPR000198
Domain-

ARHGAP25 TAGAP SYDE2

2.53e-04643631.10.555.10
DomainNicotinic_acetylcholine_rcpt

CHRNA6 CHRNB3

4.26e-0416362IPR002394
DomainZnf_RING-CH

MARCHF1 MARCHF8

4.82e-0417362IPR011016
DomainRINGv

MARCHF1 MARCHF8

4.82e-0417362SM00744
DomainRho_GTPase_activation_prot

ARHGAP25 TAGAP SYDE2

6.45e-0488363IPR008936
DomainAcetylcholine_rcpt_TM

CHRNA6 CHRNB3

8.91e-0423362IPR027361
Domain-

CHRNA6 CHRNB3

8.91e-04233621.20.120.370
DomainHomeobox

TSHZ3 TSHZ2 IRX4

1.02e-02234363PF00046
DomainHOMEOBOX_1

TSHZ3 TSHZ2 IRX4

1.05e-02236363PS00027
DomainHOX

TSHZ3 TSHZ2 IRX4

1.06e-02237363SM00389
DomainHomeobox_dom

TSHZ3 TSHZ2 IRX4

1.08e-02239363IPR001356
DomainHOMEOBOX_2

TSHZ3 TSHZ2 IRX4

1.08e-02239363PS50071
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA6 CHRNB3

7.56e-059212MM15313
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA6 CHRNB3

7.56e-059212M27597
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA6 CHRNB3

1.15e-0411212M883
PathwayREACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA6 CHRNB3

1.38e-0412212M48008
PathwayREACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNA6 CHRNB3

1.38e-0412212MM15312
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA6 CHRNB3

1.90e-0414212M757
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA6 CHRNB3

2.19e-0415212MM14704
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRR2 CHRNA6 CHRNB3

1.21e-03144213MM14501
PathwayREACTOME_NEURONAL_SYSTEM

GABRR2 CHRNA6 PANX2 CHRNB3

1.36e-03335214MM14503
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARHGAP25 TAGAP SYDE2

2.12e-03175213MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARHGAP25 TAGAP SYDE2

2.45e-03184213M41809
PathwayREACTOME_NEURONAL_SYSTEM

GABRR2 CHRNA6 PANX2 CHRNB3

2.87e-03411214M735
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRR2 CHRNA6 CHRNB3

3.32e-03205213M752
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

GABRR2 CHRNA6 CHRNB3

3.60e-03211213MM14502
Pubmed

Modulation of gain-of-function α6*-nicotinic acetylcholine receptor by β3 subunits.

CHRNA6 CHRNB3

1.10e-06237222315221
Pubmed

SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample.

CHRNA6 CHRNB3

1.10e-06237219500157
Pubmed

Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence.

CHRNA6 CHRNB3

1.10e-06237227085880
Pubmed

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.

CHRNA6 CHRNB3

1.10e-06237224401102
Pubmed

MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.

MARCHF1 MARCHF8

1.10e-06237221757542
Pubmed

A genetic variant in CHRNB3-CHRNA6 increases risk of esophageal squamous cell carcinoma in Chinese populations.

CHRNA6 CHRNB3

1.10e-06237225823894
Pubmed

Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy.

CHRNA6 CHRNB3

1.10e-06237224675634
Pubmed

Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.

CHRNA6 CHRNB3

1.10e-06237218704094
Pubmed

[Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population].

CHRNA6 CHRNB3

1.10e-06237221831805
Pubmed

The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.

CHRNA6 CHRNB3

1.10e-06237218055561
Pubmed

Nicotinic receptor gene variants interact with attention deficient hyperactive disorder symptoms to predict smoking trajectories from early adolescence to adulthood.

CHRNA6 CHRNB3

1.10e-06237223899432
Pubmed

Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population.

CHRNA6 CHRNB3

1.10e-06237228851948
Pubmed

Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.

TSHZ3 TSHZ2

1.10e-06237221423795
Pubmed

Combined effect between CHRNB3-CHRNA6 region gene variant (rs6474412) and smoking in psoriasis vulgaris severity.

CHRNA6 CHRNB3

1.10e-06237224792900
Pubmed

Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research.

CHRNA6 CHRNB3

1.10e-06237227327258
Pubmed

Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.

MARCHF1 MARCHF8

3.30e-06337223606747
Pubmed

Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development.

TSHZ3 TSHZ2

3.30e-06337216631416
Pubmed

Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens.

CHRNA6 CHRNB3

3.30e-06337221911393
Pubmed

Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.

TSHZ3 TSHZ2

3.30e-06337214973285
Pubmed

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.

MARCHF1 MARCHF8

3.30e-06337227503069
Pubmed

Efficient expression of functional (α6β2)2β3 AChRs in Xenopus oocytes from free subunits using slightly modified α6 subunits.

CHRNA6 CHRNB3

3.30e-06337225068303
Pubmed

Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.

TSHZ3 TSHZ2

3.30e-06337219745106
Pubmed

Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.

MARCHF1 MARCHF8

3.30e-06337223300075
Pubmed

Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.

MARCHF1 MARCHF8

3.30e-06337238299743
Pubmed

Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers.

CHRNA6 CHRNB3

3.30e-06337220923852
Pubmed

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.

MARCHF1 MARCHF8

6.60e-06437227503071
Pubmed

CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences.

CHRNA6 CHRNB3

6.60e-06437220854418
Pubmed

Striatal α5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum.

CHRNA6 CHRNB3

6.60e-06437222396410
Pubmed

The HLA-DRalpha chain is modified by polyubiquitination.

MARCHF1 MARCHF8

6.60e-06437219117940
Pubmed

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

CHRNA6 CHRNB3

1.10e-05537220418888
Pubmed

FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

TSHZ3 TSHZ2

2.30e-05737219343227
Pubmed

Why do young women smoke? VI. A controlled study of nicotine effects on attention: pharmacogenetic interactions.

CHRNA6 CHRNB3

2.30e-05737220231857
Pubmed

Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain.

TSHZ3 TSHZ2

3.07e-05837215834955
Pubmed

Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

CHRNA6 CHRNB3

3.95e-0593728906617
Pubmed

Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release.

CHRNA6 CHRNB3

3.95e-05937219228980
Pubmed

Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.

CHRNA6 CHRNB3

4.93e-051037220736995
Pubmed

Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus.

CHRNA6 CHRNB3

6.02e-051137212225896
Pubmed

Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission.

CHRNA6 CHRNB3

6.02e-051137229791835
Pubmed

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.

CHRNA6 CHRNB3

7.22e-051237220584212
Pubmed

Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.

CHRNA6 CHRNB3

9.94e-051437219059502
Pubmed

Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.

CHRNA6 CHRNB3

9.94e-051437223213462
Pubmed

Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.

CHRNA6 CHRNB3

1.15e-04153728838678
Pubmed

Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.

MARCHF1 MARCHF8

1.31e-041637214722266
Pubmed

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

CHRNA6 CHRNB3

1.31e-041637219259974
Pubmed

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.

MARCHF1 MARCHF8

1.67e-041837235411049
Pubmed

No evidence for association between 19 cholinergic genes and bipolar disorder.

CHRNA6 CHRNB3

1.86e-041937217373692
Pubmed

Multimodal Hox5 activity generates motor neuron diversity.

TSHZ3 TSHZ2

4.39e-042937239289460
Pubmed

AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay.

EEF2 TRRAP

4.39e-042937220371770
Pubmed

The tumor suppressor PP2A Abeta regulates the RalA GTPase.

EEF2 MARCHF1

5.35e-043237217540176
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

TSHZ3 TSHZ2

5.35e-043237216516881
Pubmed

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

TSHZ2 MARCHF8

6.41e-043537219862010
Cytoband19q12

UBA2 TSHZ3

1.19e-042037219q12
GeneFamilyRing finger proteins|Membrane associated ring-CH-type fingers

MARCHF1 MARCHF8

1.45e-041130260
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ3 TSHZ2

2.76e-0415302529
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA6 CHRNB3

3.15e-0416302173
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP25 TAGAP

3.10e-0350302721
CoexpressionGSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_DN

NTN4 TSHZ3 MARCHF1 CHRNB3

2.83e-05128364M340
CoexpressionDESCARTES_FETAL_EYE_GANGLION_CELLS

CHRNA6 IRX4 CHRNB3

4.46e-0550363M40185
CoexpressionGSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP

ANO4 MARCHF8 SYDE2 AHNAK2

5.40e-05151364M6760
ToppCelldroplet-Bladder-nan-3m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGB ARHGAP25 TAGAP MARCHF1

9.75e-061623740cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 TSHZ2 MARCHF1 DNAH7

1.51e-051813746a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 TSHZ2 CHRNB3

1.51e-051813742f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 TSHZ2 CHRNB3

1.57e-051833746e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 TSHZ2 CHRNB3

1.64e-05185374487fa382232564f075960899d50afa0edae5d258
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ANO4 ADGB UBA2 DNAH7

1.64e-05185374d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 ABCA4 SEMA4A TSHZ2

1.71e-051873749225caf66e06ebe57e90d677122acb6498607f36
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANO4 CHRNA6 TSHZ3 TSHZ2

1.71e-05187374a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TSHZ2 DNAH7 AHNAK2

1.94e-05193374ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANO4 TSHZ3 EEF2 TSHZ2

1.98e-0519437428c5482da199bcee9e85258a88af453d9fdbd56a
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EEF2 SEMA4A TAGAP MARCHF1

2.02e-05195374bf750c516e67c45c6b511909dcff934168a7bbef
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))--|Thalamus / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

3.88e-05793735c37af70dca7e9847f44d7f5969d4b06c32b4ca0
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))-|Thalamus / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

3.88e-0579373d4f9297084aea33203dd98d7f6f837b6eb00b6c3
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))|Thalamus / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

3.88e-057937375d8cbf8c7a6a4a825143f7d04a604e97bab0fe5
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

9.06e-05105373c7528276fee8f6d2cb4639069bc87413b0288025
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

9.06e-051053737bcf3345a21a1ade717128be127e9fe12ae40011
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GABRR2 CHRNA6 CHRNB3

9.06e-0510537362e89b92bb8c5187ab0205aebd018b4178710bb0
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ABCA4 DGKK AHNAK2

1.13e-0411337334ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ABCA4 DGKK AHNAK2

1.13e-0411337379ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ABCA4 DGKK AHNAK2

1.13e-0411337391d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NACC2 CHRNB3 FHIP2B

1.99e-04137373ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NACC2 CHRNB3 FHIP2B

1.99e-0413737347859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

GABRR2 TSHZ2 FHIP2B

2.12e-04140373b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TSGA13 MARCHF1 WDR87

2.21e-04142373f720f13b339589fa924a42e89393e5db0b26300b
ToppCellPND07-Immune-Immune_Myeloid-DC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 SEMA4A MARCHF1

2.45e-04147373bbc52cbea37a38058436e3fc6fc0777f83404524
ToppCellfacs-GAT-Fat-3m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A ATP7B TAGAP

2.65e-041513733d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ETV3 ATP7B MARCHF8

2.91e-041563730f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ETV3 ATP7B MARCHF8

2.91e-04156373cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TSHZ3 ARHGAP25 TSHZ2

3.20e-0416137366554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NTN4 TSHZ3 DGKK

3.25e-04162373f0a92c92c3a6cf9fa11fb279a584e7f328cb7d43
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA4A TSHZ2 AHNAK2

3.31e-041633736ed2a71385e85508ed513282c06440add7cc010c
ToppCellFrontal_cortex|World / BrainAtlas - Mouse McCarroll V32

TSHZ3 ARHGAP25 TAGAP

3.37e-04164373e09291711abf8680e78170328313719092b0142f
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 SEMA4A DGKK

3.43e-041653731c3709ac9f96ace1f3b28e1f2f15b4a8d65885ca
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 SEMA4A DGKK

3.43e-04165373fbc7d97e6f30975d35c76a7c97947a34cf5975d2
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSGA13 ABCA4 AHNAK2

3.56e-04167373d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 TAGAP MARCHF1

3.56e-041673731a6a48180481f0c13c15bb93d6ff4eeb96a5b9a0
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSGA13 ABCA4 AHNAK2

3.56e-041673737abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

ETV3 NTN4 TSHZ2

3.68e-04169373dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellfacs-Heart-LV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

3.75e-041703734eaa22040e475100061475123aefa32b56481464
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MTHFSD TSHZ3 SYDE2

3.75e-04170373aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

3.75e-0417037360041b2e57e958f300a5bc76851705c8baf297c2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 ARHGAP25 TSHZ2

3.75e-0417037387cac555f16b6c2ef3d1b3a00f992d8bf2237b50
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

3.75e-04170373793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP25 SEMA4A TSHZ2

4.01e-04174373ccc59416548ed3b783fd7a050ab32076c4296254
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

4.01e-0417437330c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

4.01e-0417437346d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF1

4.01e-041743731802a52552256d1e25d8b328ba62dcfe41671900
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 TSHZ2 MARCHF1

4.08e-04175373030f93af5a96848b9118e2a8116e19ddae438d92
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 MARCHF1 DNAH7

4.08e-04175373284fdc7a9d303636a637041846850d19d114861a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.15e-04176373cd4b9211652596c42e7af318bcd464681daebb10
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANO4 ADGB DNAH7

4.15e-041763738e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ADGB UBA2 DNAH7

4.15e-041763731c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

SEMA4A MARCHF1 PGBD3

4.15e-04176373b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NACC2 CHRNB3

4.22e-04177373fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP25 SEMA4A TSHZ2

4.22e-0417737357033ee0d49a4a50fc25328a4a44d4de2b35f505
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ADGB UBA2 DNAH7

4.22e-04177373c38138fb5ad9766c2d240811210c854338cd612e
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF8

4.29e-0417837341745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 SEMA4A MARCHF1

4.29e-04178373c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A TAGAP MARCHF8

4.29e-04178373eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.29e-041783735522b179c2e7dd707de01e2df10556349d0382a6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.29e-04178373f7f88879a05b2b5fa92cf5317b76f7a3064d1358
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB UBA2 DNAH7

4.29e-04178373255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.29e-04178373731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.43e-041803732ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 ABCA4 MARCHF1

4.43e-04180373b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 ABCA4 MARCHF1

4.43e-04180373f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A ATP7B SYDE2

4.50e-041813734e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A ATP7B SYDE2

4.50e-04181373ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A ATP7B SYDE2

4.50e-041813733a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.50e-041813736e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ADGB UBA2 DNAH7

4.57e-04182373e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.65e-04183373b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 ABCA4 TSHZ2

4.65e-04183373274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 NTN4 TSHZ3

4.65e-041833737961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-1|TCGA-Skin / Sample_Type by Project: Shred V9

ARHGAP25 TAGAP MARCHF1

4.65e-04183373cd00e2cd901df4b3f5f7aed747cc0b47f6d3c811
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.65e-04183373e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 TSHZ2 MARCHF1

4.65e-04183373cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 NTN4 DGKK

4.65e-04183373439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 ABCA4 MARCHF1

4.65e-0418337392fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 TSHZ2

4.65e-041833735e361be3ae3fe05098968e58427630127bd12675
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.79e-0418537316e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 ABCA4 SEMA4A

4.79e-041853736da9a06e1514d5d5f47359a14637f02539846096
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 TSHZ2 AHNAK2

4.79e-041853736712512100ccef456d2e2bd201d0987986c92ac9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.79e-041853734c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 ABCA4 SEMA4A

4.79e-041853734a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.79e-0418537308fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell10x5'-Liver-Myeloid_Dendritic-DC2|Liver / Manually curated celltypes from each tissue

ADGB SEMA4A MARCHF1

4.87e-0418637392ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCelltumor_Lung-B_lymphocytes|tumor_Lung / Location, Cell class and cell subclass

EEF2 TAGAP MARCHF1

4.87e-04186373a54b368d7921185c583e35b532a6898c5486c2fc
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.87e-04186373fef543f188edb0d1704d9c6ace366a0f8017bf53
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSHZ3 TSHZ2 AHNAK2

4.87e-04186373cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 NTN4 CHRNB3

4.95e-0418737302105c82a9ba79d2f19e002188377fc3440770c2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP25 TAGAP MARCHF1

4.95e-0418737383582c499cda6306fe5f66f2ac97e27ff420e228
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EEF2 ARHGAP25 PANX2

5.02e-041883730a47de24812c619f6756c9351a413b109128d54f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 NTN4 NACC2

5.10e-0418937399a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 MARCHF1 DNAH7

5.10e-04189373904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5-_Mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP25 TAGAP MARCHF1

5.18e-04190373ade43d1d1f8909b8526a23152acf3c26f160f836
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 NTN4 TSHZ3

5.18e-04190373d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell368C-Lymphocytic-B_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP25 TAGAP MARCHF1

5.18e-04190373b9abf773525f7bbc87b8c0d4e94e9d18017de82b
ToppCell368C-Lymphocytic-B_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP25 TAGAP MARCHF1

5.18e-041903731a016ae2603be5d024ba024faafd725787db8c48
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

ARHGAP25 MARCHF1 MARCHF8

5.18e-041903731e85ee686ff6dd27c69415d524d54fa825b1daad
Drugdimethylphenylpiperazinium

CHRNA6 ATP7B CHRNB3

1.21e-0459373CID000001316
DrugDns-C6-Cho

CHRNA6 CHRNB3

1.40e-0411372CID000124728
DrugAC1L9NC9

CHRNA6 CHRNB3

1.40e-0411372CID000449642
DrugDDMU

ETV3 ABCA4

1.40e-0411372CID000098491
Drugdihydronereistoxin

CHRNA6 CHRNB3

1.40e-0411372CID000121232
Drugbipinnatin-B

CHRNA6 CHRNB3

1.40e-0411372CID000127363
DrugLJP 1082

CHRNA6 CHRNB3

1.40e-0411372CID003037609
DrugAC1L9P8C

CHRNA6 CHRNB3

1.68e-0412372CID000450864
DrugSureCN373116

CHRNA6 CHRNB3

1.68e-0412372CID010085732
Drugnereistoxin

CHRNA6 CHRNB3

1.98e-0413372CID000015401
Drug1-acetyl-4-methylpiperazine methiodide

CHRNA6 CHRNB3

1.98e-0413372CID004392675
DrugC-toxiferine-I

CHRNA6 CHRNB3

1.98e-0413372CID005089093
Drugbipinnatin-C

CHRNA6 CHRNB3

1.98e-0413372CID000129977
Drugbipinnatin-A

CHRNA6 CHRNB3

1.98e-0413372CID000196603
Drug2,3-dichlorooctafluorobutane

CHRNA6 CHRNB3

2.31e-0414372CID000078982
DrugLNF 209

CHRNA6 CHRNB3

2.31e-0414372CID000132666
Drugaa373

CHRNA6 CHRNB3

2.66e-0415372CID000191672
Drug(-)-pictamine

CHRNA6 CHRNB3

2.66e-0415372CID006918623
Drug(-)-lepadin B

CHRNA6 CHRNB3

2.66e-0415372CID006918624
DrugSAD-128

CHRNA6 CHRNB3

2.66e-0415372CID000162008
Druganatoxin-a hydrochloride

CHRNA6 CHRNB3

2.66e-0415372CID000135265
DrugUB-165

CHRNA6 CHRNB3

2.66e-0415372CID004694339
DrugN-methylcytisine

CHRNA6 CHRNB3

2.66e-0415372CID000234566
DrugLynestrenol [52-76-6]; Up 200; 14uM; PC3; HT_HG-U133A

GABRR2 CHRNA6 MARCHF1 DNAH7

2.82e-041963746756_UP
DrugMetergoline [17692-51-2]; Down 200; 10uM; HL60; HG-U133A

CHRNA6 GBF1 NACC2 TRRAP

2.82e-041963741606_DN
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A

ADGB GABRR2 CHRNA6 ATP7B

2.98e-041993746324_UP
DrugMoxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A

ADGB CHRNA6 ARHGAP25 IRX4

2.98e-041993744648_UP
DrugAC1L2SVN

CHRNA6 CHRNB3

3.04e-0416372CID000127922
Drugbenzoquinonium

CHRNA6 CHRNB3

3.04e-0416372CID000009393
Drug3-(trifluoromethyl)-3-(m-iodophenyl)diazirine

CHRNA6 CHRNB3

3.04e-0416372CID000123866
DrugPNU-282,987

CHRNA6 CHRNB3

3.04e-0416372CID004655349
Drugscopolamine

ETV3 GABRR2 CHRNA6 CHRNB3

3.04e-04200374CID000005184
DrugNsc36388

CHRNA6 CHRNB3

3.44e-0417372CID000014954
Drugneostigmine

GABRR2 CHRNA6 CHRNB3

3.81e-0487373CID000004456
DrugABT-594

CHRNA6 CHRNB3

3.87e-0418372CID003075702
DrugAC1O8PVM

CHRNA6 CHRNB3

3.87e-0418372CID000004989
DrugAC1LCVGE

CHRNA6 CHRNB3

3.87e-0418372CID000656712
Drugbenzetimide

CHRNA6 CHRNB3

3.87e-0418372CID000021846
Drugisoarecolone

CHRNA6 CHRNB3

4.32e-0419372CID000146970
Drugbeta-erythroidine

CHRNA6 CHRNB3

4.32e-0419372CID000010074
DrugAC1L9P88

CHRNA6 CHRNB3

4.32e-0419372CID000450860
Drugperhydrohistrionicotoxin

CHRNA6 CHRNB3

4.32e-0419372CID000107881
DrugPNU-120596

CHRNA6 CHRNB3

4.32e-0419372CID000311434
Drug4-(N-maleimido)benzyltrimethylammonium

CHRNA6 CHRNB3

4.32e-0419372CID000162425
Drugpyridostigmine

CHRNA6 CHRNB3 PGBD3

4.64e-0493373CID000004991
DrugAC1Q5X7V

CHRNA6 CHRNB3

4.79e-0420372CID000050190
Drug3-(2-azetidinylmethoxy)pyridine

CHRNA6 CHRNB3

4.79e-0420372CID000001962
DrugDichloride, Alcuronium

CHRNA6 CHRNB3

4.79e-0420372CID003032788
Drugdinotefuran

CHRNA6 CHRNB3

5.29e-0421372CID000197701
Drugmeproadifen

CHRNA6 CHRNB3

5.29e-0421372CID000189752
Drugsuberyldicholine

CHRNA6 CHRNB3

5.82e-0422372CID000123989
Drugclothianidin

CHRNA6 CHRNB3

5.82e-0422372CID000213027
DrugAR-R17779

CHRNA6 CHRNB3

5.82e-0422372CID005310971
Drughistrionicotoxin

CHRNA6 CHRNB3

5.82e-0422372CID005282247
Drugivermectin

GABRR2 CHRNA6 CHRNB3

5.90e-04101373CID006435110
DrugABT-418

CHRNA6 CHRNB3

6.36e-0423372CID000119380
DrugAC1L3BL8

CHRNA6 CHRNB3

6.36e-0423372CID000086457
Drugalpha-conotoxin SI

CHRNA6 CHRNB3

6.36e-0423372CID000163979
DrugSkpymrfamide

CHRNA6 CHRNB3

6.36e-0423372CID000132661
Drugalpha-conotoxin ImI

CHRNA6 CHRNB3

6.36e-0423372CID000133011
DrugCID6325740

CHRNA6 CHRNB3

6.36e-0423372CID006325740
Drugprocyclidine

CHRNA6 CHRNB3

6.93e-0424372CID000004919
DrugAC1L2IZE

CHRNA6 CHRNB3

6.93e-0424372CID000072928
Drugintruder

CHRNA6 CHRNB3

6.93e-0424372CID000213021
Druganabaseine

CHRNA6 CHRNB3

6.93e-0424372CID000018985
Drugmidazolam

GABRR2 CHRNA6 CHRNB3

6.98e-04107373CID000004192
Druganabasine

CHRNA6 CHRNB3

7.53e-0425372CID000002181
Drugpempidine

CHRNA6 CHRNB3

7.53e-0425372CID000006603
DrugCys-pro

EEF2 ATP7B

7.53e-0425372CID000194366
Drugvarenicline

CHRNA6 CHRNB3

7.53e-0425372CID000170361
DrugPrBCM

CHRNA6 CHRNB3

7.53e-0425372CID000037396
Diseasecocaine use

CHRNA6 CHRNB3

8.35e-0511372C3496069
DiseaseTOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)

CHRNA6 CHRNB3

1.00e-0412372C1861063
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNA6 CHRNB3

1.82e-0416372DOID:3635 (implicated_via_orthology)
DiseaseCone-Rod Dystrophy 2

ABCA4 SEMA4A

6.08e-0429372C3489532
DiseaseLiver Dysfunction

GABRR2 ATP7B

3.70e-0372372C0086565
DiseaseLiver diseases

GABRR2 ATP7B

3.70e-0372372C0023895
DiseaseRetinitis pigmentosa

ABCA4 SEMA4A

3.90e-0374372cv:C0035334
Diseasenicotine dependence

ARHGAP25 CHRNB3

4.33e-0378372EFO_0003768
Diseasemultiple sclerosis

ETV3 TAGAP MARCHF1 SYDE2

6.34e-03594374MONDO_0005301
Diseaseovarian carcinoma

ADGB ABCA4 MARCHF1

7.54e-03321373EFO_0001075
DiseaseRetinitis Pigmentosa

ABCA4 SEMA4A

7.56e-03104372C0035334

Protein segments in the cluster

PeptideGeneStartEntry
MAPWVKRLFLQKLPK

CHRNB3

331

Q05901
PLTKIAWRAAKPLLM

ABCA4

381

P78363
LWRLMKKVQITKPPP

ADGB

846

Q8N7X0
KLSLPTRAWEPAMKK

ATP7B

21

P35670
EDALMPPKLRLKRRW

ETV3

466

P41162
RWLPKKPMRLDKETL

ANO4

211

Q32M45
ARRRLKKENKMTWPP

IRX4

196

P78413
WSRIKKILKEGPMLK

DGKK

211

Q5KSL6
PSRLPVKMWGRTLEK

GLOD5

6

A6NK44
PAKKTDIPWRLKQML

FHIP2B

46

Q86V87
IMETKLKPLRKWEKL

MARCHF8

131

Q5T0T0
IMETKLKPLRKWEKL

MARCHF1

131

Q8TCQ1
TMPRWVKTVFLKLLP

CHRNA6

336

Q15825
VMWLKPCKRADIPKR

DNAH7

3956

Q8WXX0
KWKKQKRSPRPPRHM

GBF1

226

Q92538
EGKPLLKAVMRRWLP

EEF2

331

P13639
RKPKRKRWTGQVEMP

GABRR2

21

P28476
PVVKRPRKKMKWIPT

PANX2

421

Q96RD6
VPTIMLLPLTWLSKK

MT-ND4

6

P03905
PSRRRKMTKILCKWK

PGBD3

101

Q8N328
LRPPAVTVKKLQKWM

SYDE2

181

Q5VT97
VKKRKKVLSWPFLMR

TAGAP

51

Q8N103
WKPSLGRKVMDILKR

NTN4

611

Q9HB63
RLKNMIPWPASDRKK

SEMA4A

96

Q9H3S1
LLTMDKLWRKRKPPV

UBA2

266

Q9UBT2
LKKRPKWKRVLPSLL

SPATA31E1

571

Q6ZUB1
SPLKMPKIKLPSFRW

AHNAK2

4951

Q8IVF2
LPRELKPNKKYSWMR

TNRC18

1446

O15417
LWLPRMPQKKKLRSK

TSGA13

141

Q96PP4
RPIKMGWLKKQRSIV

ARHGAP25

46

P42331
KRPKPMGITWFKISL

MTHFSD

216

Q2M296
LTNKLRPIAPKWKVM

TSHZ2

571

Q9NRE2
PKRWSKPRKRSLLEM

TSHZ3

251

Q63HK5
IERKKWMNIRPLPTK

ZC3H7A

751

Q8IWR0
RSKPWPMAKKLTELR

TMC2

171

Q8TDI7
MSSPRLIPLWKDLKL

WDR87

1

Q6ZQQ6
KTALRPDMWPKSELK

TRRAP

2131

Q9Y4A5
RVRKRWLPKIKSMLP

NACC2

446

Q96BF6