Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontrace-amine receptor activity

TAAR6 TAAR3P TAAR9

6.95e-098113GO:0001594
GeneOntologyMolecularFunctionG protein-coupled photoreceptor activity

OPN1MW2 OPN1MW OPN1MW3

5.64e-0815113GO:0008020
GeneOntologyMolecularFunctionphotoreceptor activity

OPN1MW2 OPN1MW OPN1MW3

8.42e-0817113GO:0009881
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

TAAR6 TAAR3P TAAR9

1.31e-0641113GO:0008227
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OPN1MW2 TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

2.82e-06884116GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OPN1MW2 TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

3.29e-051353116GO:0004888
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP8B4 ATP8B2

1.03e-0428112GO:0140326
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP8B4 ATP8B2

3.47e-0451112GO:0140303
GeneOntologyMolecularFunctiontransporter activity

SCN11A ATP8B4 SLC16A1 ATP8B2

3.95e-031289114GO:0005215
GeneOntologyMolecularFunctionlipid transporter activity

ATP8B4 ATP8B2

4.97e-03196112GO:0005319
GeneOntologyMolecularFunctionmagnesium ion binding

ATP8B4 ATP8B2

7.79e-03247112GO:0000287
GeneOntologyBiologicalProcessdetection of external stimulus

SCN11A OPN1MW2 OPN1MW OPN1MW3

1.51e-06173114GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN11A OPN1MW2 OPN1MW OPN1MW3

1.58e-06175114GO:0009582
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

SCN11A OPN1MW2 TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

1.65e-061395117GO:0007186
GeneOntologyBiologicalProcessphototransduction

OPN1MW2 OPN1MW OPN1MW3

2.61e-0653113GO:0007602
GeneOntologyBiologicalProcessdetection of visible light

OPN1MW2 OPN1MW OPN1MW3

3.25e-0657113GO:0009584
GeneOntologyBiologicalProcessdetection of light stimulus

OPN1MW2 OPN1MW OPN1MW3

8.08e-0677113GO:0009583
GeneOntologyBiologicalProcessresponse to light stimulus

SCN11A OPN1MW2 OPN1MW OPN1MW3

3.45e-05382114GO:0009416
GeneOntologyBiologicalProcesscellular response to light stimulus

OPN1MW2 OPN1MW OPN1MW3

3.89e-05130113GO:0071482
GeneOntologyBiologicalProcessresponse to radiation

SCN11A OPN1MW2 OPN1MW OPN1MW3

1.01e-04503114GO:0009314
GeneOntologyBiologicalProcesscellular response to radiation

OPN1MW2 OPN1MW OPN1MW3

1.28e-04194113GO:0071478
GeneOntologyBiologicalProcesssensory perception

SCN11A OPN1MW2 TAAR3P OPN1MW OPN1MW3

1.33e-041072115GO:0007600
GeneOntologyBiologicalProcessvisual perception

OPN1MW2 OPN1MW OPN1MW3

2.11e-04230113GO:0007601
GeneOntologyBiologicalProcesssensory perception of light stimulus

OPN1MW2 OPN1MW OPN1MW3

2.20e-04233113GO:0050953
GeneOntologyBiologicalProcesspositive regulation of cytokinesis

OPN1MW2 OPN1MW

3.78e-0455112GO:0032467
GeneOntologyBiologicalProcessphospholipid translocation

ATP8B4 ATP8B2

3.78e-0455112GO:0045332
GeneOntologyBiologicalProcessdetection of stimulus

SCN11A OPN1MW2 OPN1MW OPN1MW3

4.04e-04722114GO:0051606
GeneOntologyBiologicalProcessresponse to abiotic stimulus

SCN11A OPN1MW2 SLU7 OPN1MW OPN1MW3

4.10e-041361115GO:0009628
GeneOntologyBiologicalProcesslipid translocation

ATP8B4 ATP8B2

4.50e-0460112GO:0034204
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ATP8B4 ATP8B2

5.28e-0465112GO:0097035
GeneOntologyBiologicalProcesscellular response to abiotic stimulus

OPN1MW2 OPN1MW OPN1MW3

8.56e-04371113GO:0071214
GeneOntologyBiologicalProcesscellular response to environmental stimulus

OPN1MW2 OPN1MW OPN1MW3

8.56e-04371113GO:0104004
GeneOntologyBiologicalProcessregulation of cytokinesis

OPN1MW2 OPN1MW

1.22e-0399112GO:0032465
GeneOntologyBiologicalProcesspositive regulation of cell division

OPN1MW2 OPN1MW

1.34e-03104112GO:0051781
GeneOntologyBiologicalProcessphospholipid transport

ATP8B4 ATP8B2

1.40e-03106112GO:0015914
GeneOntologyBiologicalProcessresponse to heat

SCN11A SLU7

1.81e-03121112GO:0009408
GeneOntologyBiologicalProcessorganophosphate ester transport

ATP8B4 ATP8B2

3.22e-03162112GO:0015748
GeneOntologyBiologicalProcessGolgi organization

ATP8B4 ATP8B2

3.46e-03168112GO:0007030
GeneOntologyBiologicalProcessregulation of cell division

OPN1MW2 OPN1MW

4.90e-03201112GO:0051302
GeneOntologyBiologicalProcesscytokinesis

OPN1MW2 OPN1MW

5.05e-03204112GO:0000910
GeneOntologyBiologicalProcessresponse to temperature stimulus

SCN11A SLU7

5.24e-03208112GO:0009266
GeneOntologyBiologicalProcesspositive regulation of cell cycle process

OPN1MW2 OPN1MW

1.11e-02307112GO:0090068
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN1MW2 OPN1MW OPN1MW3

2.80e-0726113GO:0097381
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP8B4 ATP8B2

2.28e-0514112GO:1990531
GeneOntologyCellularComponentphotoreceptor outer segment

OPN1MW2 OPN1MW OPN1MW3

2.33e-05111113GO:0001750
GeneOntologyCellularComponentphotoreceptor cell cilium

OPN1MW2 OPN1MW OPN1MW3

4.57e-05139113GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

OPN1MW2 OPN1MW OPN1MW3

6.08e-05153113GO:0097731
GeneOntologyCellularComponentnon-motile cilium

OPN1MW2 OPN1MW OPN1MW3

1.27e-04196113GO:0097730
GeneOntologyCellularComponenttransporter complex

SCN11A ATP8B4 ATP8B2

2.55e-03550113GO:1990351
MousePhenoincreased bone mineral content

ATP8B4 TAAR6 ATP8B2

4.81e-0425893MP:0010123
MousePhenodecreased b-wave amplitude

OPN1MW2 OPN1MW3

1.19e-038292MP:0012144
MousePhenoabnormal b-wave shape

OPN1MW2 OPN1MW3

1.28e-038592MP:0012035
MousePhenoabnormal b-wave amplitude

OPN1MW2 OPN1MW3

1.28e-038592MP:0012031
MousePhenoabnormal vision

OPN1MW2 OPN1MW3

1.40e-038992MP:0002090
MousePhenoabnormal electroretinogram waveform feature

OPN1MW2 OPN1MW3

1.98e-0310692MP:0012029
DomainTAAR_fam

TAAR6 TAAR3P TAAR9

3.86e-097103IPR009132
DomainOpsin_red/grn

OPN1MW OPN1MW3

7.74e-073102IPR000378
DomainOPSIN

OPN1MW OPN1MW3

1.16e-0510102PS00238
Domain7tm_1

TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

1.34e-05677105PF00001
DomainG_PROTEIN_RECEP_F1_1

TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

1.41e-05685105PS00237
DomainOpsin

OPN1MW OPN1MW3

1.42e-0511102IPR001760
DomainG_PROTEIN_RECEP_F1_2

TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

1.47e-05691105PS50262
DomainGPCR_Rhodpsn

TAAR6 TAAR3P OPN1MW TAAR9 OPN1MW3

1.49e-05692105IPR000276
DomainP_typ_ATPase_c

ATP8B4 ATP8B2

2.34e-0514102IPR032630
DomainPhoLip_ATPase_C

ATP8B4 ATP8B2

2.34e-0514102PF16212
DomainPhoLip_ATPase_N

ATP8B4 ATP8B2

2.34e-0514102PF16209
DomainP-type_ATPase_N

ATP8B4 ATP8B2

2.34e-0514102IPR032631
DomainP-type_ATPase_IV

ATP8B4 ATP8B2

2.34e-0514102IPR006539
Domain7TM_GPCR_Srsx

TAAR6 TAAR9 OPN1MW3

2.44e-05112103SM01381
Domain-

ATP8B4 ATP8B2

1.27e-04321022.70.150.10
Domain-

ATP8B4 ATP8B2

1.27e-04321023.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP8B4 ATP8B2

1.52e-0435102IPR023299
DomainATPASE_E1_E2

ATP8B4 ATP8B2

1.61e-0436102PS00154
DomainATPase_P-typ_P_site

ATP8B4 ATP8B2

1.61e-0436102IPR018303
DomainP_typ_ATPase

ATP8B4 ATP8B2

1.61e-0436102IPR001757
DomainATPase_P-typ_transduc_dom_A

ATP8B4 ATP8B2

1.70e-0437102IPR008250
DomainE1-E2_ATPase

ATP8B4 ATP8B2

1.70e-0437102PF00122
DomainGPCR_Rhodpsn_7TM

TAAR6 OPN1MW TAAR9 OPN1MW3

2.90e-04670104IPR017452
Domain-

ATP8B4 ATP8B2

5.11e-04641023.40.50.1000
DomainHAD-like_dom

ATP8B4 ATP8B2

7.78e-0479102IPR023214
PathwayWP_GPCRS_ODORANT

OPN1MW2 TAAR6 TAAR3P TAAR9 OPN1MW3

7.04e-08157115MM15872
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OPN1MW2 TAAR6 TAAR3P TAAR9 OPN1MW3

2.93e-06333115MM14963
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

TAAR6 TAAR3P TAAR9

3.99e-0642113MM14971
PathwayREACTOME_GPCR_LIGAND_BINDING

OPN1MW2 TAAR6 TAAR3P TAAR9 OPN1MW3

1.02e-05430115MM15160
PathwayREACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION

OPN1MW2 OPN1MW3

1.55e-058112MM14880
PathwayREACTOME_OPSINS

OPN1MW2 OPN1MW3

2.48e-0510112MM15063
PathwayREACTOME_SIGNALING_BY_GPCR

OPN1MW2 TAAR6 TAAR3P TAAR9 OPN1MW3

7.30e-05646115MM14962
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

TAAR6 TAAR3P TAAR9

1.59e-04143113MM15055
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

TAAR6 TAAR9

4.69e-0442112M5868
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP8B4 ATP8B2

8.04e-0455112M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP8B4 ATP8B2

8.63e-0457112MM15643
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

TAAR6 OPN1MW TAAR9

1.82e-03330113M18334
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

OPN1MW2 OPN1MW3

2.23e-0392112MM14881
PathwayREACTOME_GPCR_LIGAND_BINDING

TAAR6 OPN1MW TAAR9

4.77e-03463113M507
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

TAAR6 TAAR9

6.35e-03157112M4904
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B4 ATP8B2

7.92e-03176112MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B4 ATP8B2

8.53e-03183112M997
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OPN1MW2 OPN1MW3

8.81e-03186112MM15994
PathwayREACTOME_SENSORY_PERCEPTION

OPN1MW2 OPN1MW3

9.17e-03190112MM15687
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP8B4 SLC16A1 ATP8B2

1.38e-02681113MM14985
PathwayREACTOME_SIGNALING_BY_GPCR

TAAR6 OPN1MW TAAR9

1.50e-02702113M746
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP8B4 SLC16A1 ATP8B2

1.71e-02736113M27287
Pubmed

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

OPN1MW2 OPN1MW OPN1MW3

9.41e-11411329386880
Pubmed

Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

OPN1MW2 OPN1MW OPN1MW3

2.35e-1051132937147
Pubmed

A second class of chemosensory receptors in the olfactory epithelium.

TAAR6 TAAR3P TAAR9

1.97e-09911316878137
Pubmed

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

TAAR6 TAAR3P TAAR9

1.97e-09911315718104
Pubmed

Expression of trace amine-associated receptors in the Grueneberg ganglion.

TAAR6 TAAR3P TAAR9

2.82e-091011317556730
Pubmed

Discovery of a null mutation in a human trace amine receptor gene.

TAAR3P TAAR9

9.09e-08211214559210
Pubmed

Defective colour vision associated with a missense mutation in the human green visual pigment gene.

OPN1MW2 OPN1MW

9.09e-0821121302020
Pubmed

Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.

OPN1MW2 OPN1MW

9.09e-08211228402104
Pubmed

Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.

OPN1MW2 OPN1MW

9.09e-08211210319869
Pubmed

Emergence of novel color vision in mice engineered to express a human cone photopigment.

OPN1MW2 OPN1MW3

2.73e-07311217379811
Pubmed

Co-expression of murine opsins facilitates identifying the site of cone adaptation.

OPN1MW2 OPN1MW3

2.73e-07311212511072
Pubmed

Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).

OPN1MW2 OPN1MW3

2.73e-07311210567724
Pubmed

Multiple hypothalamic cell populations encoding distinct visual information.

OPN1MW2 OPN1MW3

2.73e-07311221224225
Pubmed

Molecular determinants of human red/green color discrimination.

OPN1MW2 OPN1MW

2.73e-0731128185948
Pubmed

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.

OPN1MW2 OPN1MW3

2.73e-07311228751656
Pubmed

Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.

OPN1MW2 OPN1MW3

2.73e-07311236216501
Pubmed

X-linked cone dystrophy caused by mutation of the red and green cone opsins.

OPN1MW2 OPN1MW

2.73e-07311220579627
Pubmed

Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.

OPN1MW2 OPN1MW3

2.73e-07311231469404
Pubmed

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.

OPN1MW2 OPN1MW3

2.73e-0731127958444
Pubmed

Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.

OPN1MW2 OPN1MW3

2.73e-07311214500905
Pubmed

Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

OPN1MW2 OPN1MW3

2.73e-07311238410159
Pubmed

Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.

OPN1MW2 OPN1MW3

2.73e-07311223350963
Pubmed

The molecular genetics and evolution of red and green color vision in vertebrates.

OPN1MW2 OPN1MW3

2.73e-07311211545071
Pubmed

Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.

OPN1MW2 OPN1MW3

2.73e-07311234111401
Pubmed

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.

OPN1MW2 OPN1MW3

2.73e-07311220471354
Pubmed

Mechanisms of spectral tuning in the mouse green cone pigment.

OPN1MW2 OPN1MW3

2.73e-0731129238068
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

OPN1MW2 TAAR6 TAAR3P TAAR9

3.39e-0720011418240029
Pubmed

Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.

OPN1MW2 OPN1MW3

5.45e-07411216567464
Pubmed

Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.

OPN1MW2 OPN1MW3

5.45e-07411226438865
Pubmed

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.

OPN1MW2 OPN1MW3

5.45e-07411231461375
Pubmed

S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.

OPN1MW2 OPN1MW3

5.45e-07411224801621
Pubmed

Molecular biology of the visual pigments.

OPN1MW2 OPN1MW

5.45e-0741123303660
Pubmed

Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.

OPN1MW2 OPN1MW3

5.45e-0741128088841
Pubmed

FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body.

ATP8B4 ATP8B2

5.45e-07411212880872
Pubmed

Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.

OPN1MW2 OPN1MW3

5.45e-07411231846668
Pubmed

Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.

OPN1MW2 OPN1MW3

5.45e-07411217249565
Pubmed

Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.

OPN1MW2 OPN1MW3

5.45e-07411228103478
Pubmed

Melanopsin Contributions to the Representation of Images in the Early Visual System.

OPN1MW2 OPN1MW3

5.45e-07411228528909
Pubmed

Melanopsin-driven light adaptation in mouse vision.

OPN1MW2 OPN1MW3

5.45e-07411225308073
Pubmed

Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.

OPN1MW2 OPN1MW3

5.45e-07411238060327
Pubmed

Contribution of M-opsin-based color vision to refractive development in mice.

OPN1MW2 OPN1MW3

5.45e-07411234126082
Pubmed

Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.

OPN1MW2 OPN1MW3

9.09e-07511226818794
Pubmed

Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.

OPN1MW2 OPN1MW3

9.09e-07511234099749
Pubmed

Trace amines: identification of a family of mammalian G protein-coupled receptors.

TAAR6 TAAR9

9.09e-07511211459929
Pubmed

Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.

OPN1MW2 OPN1MW3

9.09e-07511236631163
Pubmed

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

OPN1MW2 OPN1MW3

9.09e-07511211055434
Pubmed

Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.

OPN1MW2 OPN1MW3

9.09e-07511227033727
Pubmed

A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.

OPN1MW2 OPN1MW3

9.09e-07511222090509
Pubmed

Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.

OPN1MW2 OPN1MW3

9.09e-07511210723722
Pubmed

Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.

OPN1MW2 OPN1MW3

9.09e-07511224058409
Pubmed

A common integration locus in type B retrovirus-induced thymic lymphomas.

OPN1MW2 OPN1MW3

9.09e-0751121333116
Pubmed

Melanopsin-based brightness discrimination in mice and humans.

OPN1MW2 OPN1MW3

9.09e-07511222633808
Pubmed

Structural basis of amine odorant perception by a mammal olfactory receptor.

TAAR6 TAAR9

9.09e-07511237225986
Pubmed

An olfactory subsystem that mediates high-sensitivity detection of volatile amines.

TAAR3P TAAR9

1.36e-06611222840399
Pubmed

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

OPN1MW2 OPN1MW3

1.36e-06611223288843
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

OPN1MW2 OPN1MW3

1.36e-0661128872469
Pubmed

Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.

OPN1MW2 OPN1MW3

1.36e-06611217436273
Pubmed

A thyroid hormone receptor that is required for the development of green cone photoreceptors.

OPN1MW2 OPN1MW3

1.36e-06611211138006
Pubmed

GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina.

OPN1MW2 OPN1MW

1.36e-06611212853434
Pubmed

Telomere-related markers for the pseudoautosomal region of the mouse genome.

OPN1MW2 OPN1MW3

1.36e-0661121549575
Pubmed

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.

OPN1MW2 OPN1MW3

1.36e-06611210395695
Pubmed

NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.

OPN1MW2 OPN1MW3

1.91e-06711218199774
Pubmed

CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.

ATP8B4 ATP8B2

1.91e-06711220961850
Pubmed

Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.

ATP8B4 ATP8B2

1.91e-06711220947505
Pubmed

Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

OPN1MW2 OPN1MW3

1.91e-06711216574740
Pubmed

Rods progressively escape saturation to drive visual responses in daylight conditions.

OPN1MW2 OPN1MW3

1.91e-06711229180667
Pubmed

Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.

OPN1MW2 OPN1MW3

1.91e-06711218974269
Pubmed

Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.

OPN1MW2 OPN1MW3

1.91e-0671129880679
Pubmed

Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.

OPN1MW2 OPN1MW3

1.91e-06711230799247
Pubmed

Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.

OPN1MW2 OPN1MW3

1.91e-06711219332056
Pubmed

Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.

OPN1MW2 OPN1MW3

1.91e-0671128001979
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

OPN1MW2 OPN1MW3

1.91e-0671128378320
Pubmed

Tubby is required for trafficking G protein-coupled receptors to neuronal cilia.

OPN1MW2 OPN1MW3

2.54e-06811223351594
Pubmed

A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3).

OPN1MW2 OPN1MW3

2.54e-06811210725384
Pubmed

X-chromosome gene order in different Mus species crosses.

OPN1MW2 OPN1MW3

2.54e-0681123416629
Pubmed

Localization of the mdx mutation within the mouse dystrophin gene.

OPN1MW2 OPN1MW3

2.54e-0681122903046
Pubmed

Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.

OPN1MW2 OPN1MW3

2.54e-06811216043864
Pubmed

The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.

OPN1MW2 OPN1MW3

2.54e-06811212651948
Pubmed

Genetic mapping on the mouse X chromosome of human cDNA clones for the fragile X and Hunter syndromes.

OPN1MW2 OPN1MW3

2.54e-0681121572654
Pubmed

Nr2e3 functional domain ablation by CRISPR-Cas9D10A identifies a new isoform and generates retinitis pigmentosa and enhanced S-cone syndrome models.

OPN1MW2 OPN1MW3

2.54e-06811233007388
Pubmed

Linkage of amelogenin (Amel) to the distal portion of the mouse X chromosome.

OPN1MW2 OPN1MW3

2.54e-0681121675194
Pubmed

Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation.

OPN1MW2 OPN1MW3

2.54e-06811231163126
Pubmed

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors.

OPN1MW2 OPN1MW3

2.54e-06811220203194
Pubmed

Two transcription factors can direct three photoreceptor outcomes from rod precursor cells in mouse retinal development.

OPN1MW2 OPN1MW3

2.54e-06811221813673
Pubmed

Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network.

OPN1MW2 OPN1MW3

3.27e-06911228370415
Pubmed

Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium.

OPN1MW2 OPN1MW3

3.27e-06911214742273
Pubmed

Feedback induction of a photoreceptor-specific isoform of retinoid-related orphan nuclear receptor β by the rod transcription factor NRL.

OPN1MW2 OPN1MW3

3.27e-06911225296752
Pubmed

IFT20 is required for opsin trafficking and photoreceptor outer segment development.

OPN1MW2 OPN1MW3

3.27e-06911221307337
Pubmed

Comparative mapping of the actin-binding protein 280 genes in human and mouse.

OPN1MW2 OPN1MW3

3.27e-0691128088838
Pubmed

Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.

OPN1MW2 OPN1MW3

3.27e-06911212407160
Pubmed

A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction.

OPN1MW2 OPN1MW3

3.27e-06911227669145
Pubmed

Multilocus molecular mapping of the mouse X chromosome.

OPN1MW2 OPN1MW3

3.27e-0691122906327
Pubmed

Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.

OPN1MW2 OPN1MW3

3.27e-0691121973136
Pubmed

ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse.

OPN1MW2 OPN1MW3

3.27e-06911221850176
Pubmed

Comparative mapping on the mouse and human X chromosomes of a human cDNA clone encoding the vasopressin renal-type receptor (AVP2R).

OPN1MW2 OPN1MW3

4.09e-06101128449515
Pubmed

The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.

OPN1MW2 OPN1MW3

4.09e-061011232236127
Pubmed

Mapping of ornithine aminotransferase gene sequences to mouse chromosomes 7, X, and 3.

OPN1MW2 OPN1MW3

4.09e-06101121349842
Pubmed

Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.

OPN1MW2 OPN1MW3

4.09e-061011231949211
Pubmed

Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye.

OPN1MW2 OPN1MW3

4.09e-061011221148184
Pubmed

Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28.

OPN1MW2 OPN1MW3

4.09e-06101121684949
InteractionATP8B4 interactions

ATP8B4 ATP8B2

2.07e-06682int:ATP8B4
InteractionATP8B2 interactions

ATP8B4 ATP8B2

1.24e-044382int:ATP8B2
InteractionCHCHD10 interactions

SLC16A1 ATP8B2

3.77e-047582int:CHCHD10
CytobandEnsembl 112 genes in cytogenetic band chr6q23

TAAR6 TAAR3P TAAR9

2.76e-06119113chr6q23
Cytoband6q23.2

TAAR6 TAAR9

1.56e-05251126q23.2
CytobandEnsembl 112 genes in cytogenetic band chrXq28

OPN1MW2 OPN1MW OPN1MW3

1.58e-05213113chrXq28
CytobandXq28

OPN1MW2 OPN1MW

7.86e-04176112Xq28
GeneFamilyTrace amine receptors

TAAR6 TAAR3P TAAR9

1.02e-089103188
GeneFamilyOpsin receptors

OPN1MW2 OPN1MW OPN1MW3

2.01e-0811103215
GeneFamilyATPase phospholipid transporting

ATP8B4 ATP8B2

2.88e-05151021210
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SCN11A ATP8B4

1.32e-0478102869fcbc0c308164101c0e4e0494c6a75c2f6f94e
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SCN11A ATP8B4

1.32e-047810246e31ebb3afc08bf414a5793cd9b4320bf4375c5
ToppCell(05)_Ciliated-(2)_48hpi|(05)_Ciliated / shred by cell type and Timepoint

SCN11A OPN1MW

3.34e-04124102fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 SLU7

4.50e-041441021efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 SLU7

4.50e-04144102c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 ATP8B2

4.82e-0414910248fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4|TCGA-Bladder / Sample_Type by Project: Shred V9

SCN11A TAAR6

4.88e-04150102bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SCN11A ATP8B2

4.95e-04151102d19fc363ba1d7ff77e0adcaacafa4c64e1143f40
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-3|TCGA-Endometrium / Sample_Type by Project: Shred V9

TAAR6 TAAR9

5.35e-04157102ef70abc999be3a2c1eed7d21aef4b484f69d8567
ToppCellCOVID-19_Severe-Treg|World / disease group, cell group and cell class

SLC16A1 ATP8B2

5.62e-04161102c6eade2c60c572d823e6e81b5e8d47078671e9b0
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP8B4 ATP8B2

5.90e-0416510294a5211072464fc24592bb107a853ce832e816fe
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC16A1 ATP8B2

5.90e-041651029ccce713d4122054bf4bef4a7126d90cf9141b84
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC16A1 ATP8B2

5.90e-04165102dbe231d00843cae917efd1abea6079ace3b45cdf
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

SLC16A1 ATP8B2

5.97e-041661024ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 ATP8B2

6.12e-0416810293b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 SLC16A1

6.12e-04168102fa0d251693935116adf633d02b7ec4a295100865
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 ATP8B2

6.12e-04168102e393553208617a023f1646169c892a87c95db3f5
ToppCellCOVID-19_Severe-Treg|COVID-19_Severe / disease group, cell group and cell class

SLC16A1 ATP8B2

6.26e-04170102d61269a51283125835884c4aa50623756c4fdda2
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ATP8B4 SLC16A1

6.41e-04172102dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ATP8B4 SLC16A1

6.41e-0417210204fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

SCN11A ATP8B4

6.41e-04172102a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A ATP8B4

6.56e-0417410287fa5deff5c1aabb342d674f05ad17c4c0e50d01
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A OPN1MW

7.33e-041841023da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC16A1 ATP8B2

7.56e-041871029fdfca5b70f585843ef9d810154674a8e561e765
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC16A1 ATP8B2

7.56e-04187102a525753a8a908ee1ef0b8f06e68855e4af27bf86
ToppCellEndothelial-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SLC16A1 ATP8B2

7.65e-04188102ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCellCOVID-19_Severe-Treg|COVID-19_Severe / Disease condition and Cell class

SLC16A1 ATP8B2

7.89e-0419110206fdd76ea13b93e29959c745698b57af6746aaeb
ToppCellCOVID-19_Severe-Lymphoid_T/NK-Treg|COVID-19_Severe / Disease group, lineage and cell class

SLC16A1 ATP8B2

7.97e-041921023fb4c148dadcf5e79094e55c6bb53ec7bf9d44c8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC16A1 ATP8B2

7.97e-04192102d883b91bbab71673de4858346d3ab33e5fbbf842
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC16A1 ATP8B2

7.97e-041921027a90ec9fc8f29216c4828e0cf5d040906456e53b
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 SLC16A1

8.05e-0419310244ba79db566d0fa3bbcfe3adf9164bf8c3cb0bc3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 SLC16A1

8.05e-04193102f92bbe70e6c725bfb8c08bfc2a94e375528151a3
ToppCellsevere-Treg|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC16A1 ATP8B2

8.47e-041981024935b40fc848037a06055f30d90bde940b9d5321
ToppCellmild-Treg|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC16A1 ATP8B2

8.47e-041981020269617c0628003d2a13dab98abfd2d15775d16a
ToppCellsevere-Treg|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC16A1 ATP8B2

8.47e-04198102377980b9f7d02818e1d145e6884604f8bfacc4f2
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-Treg|COVID-19_Severe / Disease, condition lineage and cell class

SLC16A1 ATP8B2

8.64e-042001022b363f2a1d08019b6ff0b10419870049063cc1cf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Glia_progenitor_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ATP8B4 SLC16A1

8.64e-042001020b91c8da21ba488109f15c9b927c1dcaf8c6b0ae
Diseaseblue cone monochromacy (implicated_via_orthology)

OPN1MW2 OPN1MW OPN1MW3

1.54e-104113DOID:0050679 (implicated_via_orthology)
Diseasemigraine disorder

SCN11A TAAR6

7.47e-03357112MONDO_0005277
Diseaseeosinophil percentage of leukocytes

OPN1MW2 OPN1MW3

3.02e-02746112EFO_0007991

Protein segments in the cluster

PeptideGeneStartEntry
VHFWFGFFCGFSAQT

ATP8B4

886

Q8TF62
FTMVHFWFGFFCGFS

ATP8B2

901

P98198
FWFGFFCGFSAQTVY

ATP8B2

906

P98198
AFCFCWGPYAFFACF

OPN1MW3

276

P0DN78
AFCFCWGPYAFFACF

OPN1MW2

276

P0DN77
FCVYAGFFGFAFGWL

SLC16A1

356

P53985
AFCFCWGPYAFFACF

OPN1MW

276

P04001
CWYFGDGFCKFHTSF

TAAR3P

96

Q9P1P4
SCWYFGRSFCTFHTC

TAAR6

96

Q96RI8
SCWYFGDSYCKFHTC

TAAR9

96

Q96RI9
WGYKCCHSFFKYSYC

SLU7

441

O95391
AFGFGKYFTSAWCCL

SCN11A

1111

Q9UI33