| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF502 ZNF717 ZNF133 ZNF136 ZNF142 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF722 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF840P ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 KDM6A ZNF287 ZNF445 | 9.16e-35 | 1459 | 109 | 56 | GO:0000977 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | ZNF502 ZNF717 ZNF133 ZNF136 ZNF142 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF722 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF840P ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF160 ZNF287 ZNF445 | 6.38e-30 | 1412 | 109 | 51 | GO:0000981 |
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | ZNF502 ZNF717 ZNF136 ZNF493 ZNF473 PATZ1 ZSCAN4 ZNF722 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF840P ZNF284 ZNF2 ZNF331 ZNF7 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 KDM6A ZNF287 ZNF445 | 5.82e-24 | 1244 | 109 | 43 | GO:0000978 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | ZNF502 ZNF717 ZNF136 ZNF493 ZNF473 PATZ1 ZSCAN4 ZNF722 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF840P ZNF284 ZNF2 ZNF331 ZNF7 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 KDM6A ZNF287 ZNF445 | 1.36e-23 | 1271 | 109 | 43 | GO:0000987 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | ZNF717 ZNF493 ZNF473 VEZF1 PATZ1 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 YY1 ZNF840P ZNF836 ZNF33A ZNF197 ZNF778 ZNF445 | 9.66e-09 | 560 | 109 | 17 | GO:0001228 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | ZNF717 ZNF493 ZNF473 VEZF1 PATZ1 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 YY1 ZNF840P ZNF836 ZNF33A ZNF197 ZNF778 ZNF445 | 1.13e-08 | 566 | 109 | 17 | GO:0001216 |
| GeneOntologyMolecularFunction | prostanoid receptor binding | RPGRIP1L FEM1A | 8.83e-05 | 3 | 109 | 2 | GO:0031862 |
| GeneOntologyBiologicalProcess | atrial cardiac muscle cell membrane repolarization | CACNA1D FLNA KCNJ5 | 2.30e-05 | 11 | 109 | 3 | GO:0099624 |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | ZNF717 ZNF142 ZNF493 ZNF473 VEZF1 PATZ1 ZNF780B ZNF485 ZNF224 ZNF225 ZNF229 YY1 ZNF840P ZNF836 ZNF33A CCDC62 ZNF197 CKAP2 KDM6A ZNF445 | 3.63e-05 | 1390 | 109 | 20 | GO:0045944 |
| GeneOntologyCellularComponent | procentriole | CEP192 CEP152 | 8.20e-05 | 3 | 110 | 2 | GO:0120098 |
| GeneOntologyCellularComponent | procentriole replication complex | CEP192 CEP152 | 4.06e-04 | 6 | 110 | 2 | GO:0120099 |
| HumanPheno | Patent foramen ovale | CACNA1D FLNA POLR1A YY1 NF1 KDM6A | 2.16e-05 | 135 | 23 | 6 | HP:0001655 |
| HumanPheno | Facial asymmetry | FLNA POLR1A YY1 NF1 KCNJ5 CEP152 | 3.79e-05 | 149 | 23 | 6 | HP:0000324 |
| Domain | Znf_C2H2/integrase_DNA-bd | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 2.77e-53 | 694 | 106 | 57 | IPR013087 |
| Domain | - | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF222 ZNF445 | 2.58e-52 | 679 | 106 | 56 | 3.30.160.60 |
| Domain | zf-C2H2 | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 8.18e-52 | 693 | 106 | 56 | PF00096 |
| Domain | ZINC_FINGER_C2H2_2 | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 1.55e-50 | 775 | 106 | 57 | PS50157 |
| Domain | ZINC_FINGER_C2H2_1 | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 1.80e-50 | 777 | 106 | 57 | PS00028 |
| Domain | Znf_C2H2-like | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 7.12e-50 | 796 | 106 | 57 | IPR015880 |
| Domain | Znf_C2H2 | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 1.35e-49 | 805 | 106 | 57 | IPR007087 |
| Domain | ZnF_C2H2 | ZNF502 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF654 ZNF287 ZNF222 ZNF445 | 1.67e-49 | 808 | 106 | 57 | SM00355 |
| Domain | KRAB | ZNF133 ZNF136 ZNF234 ZNF155 ZNF473 ZNF337 ZNF875 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF251 ZIM3 ZKSCAN5 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF33A ZNF334 ZNF732 ZNF436 ZNF197 ZNF778 ZNF528 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 1.39e-44 | 358 | 106 | 42 | PS50805 |
| Domain | KRAB | ZNF133 ZNF136 ZNF234 ZNF155 ZNF473 ZNF337 ZNF875 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF251 ZIM3 ZKSCAN5 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF33A ZNF334 ZNF732 ZNF436 ZNF197 ZNF778 ZNF528 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 1.39e-44 | 358 | 106 | 42 | PF01352 |
| Domain | KRAB | ZNF133 ZNF136 ZNF234 ZNF155 ZNF473 ZNF337 ZNF875 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF251 ZIM3 ZKSCAN5 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF33A ZNF334 ZNF732 ZNF436 ZNF197 ZNF778 ZNF528 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 5.17e-44 | 369 | 106 | 42 | SM00349 |
| Domain | KRAB | ZNF133 ZNF136 ZNF234 ZNF155 ZNF473 ZNF337 ZNF875 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF251 ZIM3 ZKSCAN5 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF33A ZNF334 ZNF732 ZNF436 ZNF197 ZNF778 ZNF528 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 5.81e-44 | 370 | 106 | 42 | IPR001909 |
| Domain | zf-C2H2_6 | ZNF502 ZNF133 ZNF136 ZNF234 ZNF155 ZNF493 ZNF473 PATZ1 ZNF780B ZNF224 ZNF225 ZNF229 ZNF236 ZNF865 ZNF251 ZIM3 ZKSCAN5 ZNF284 ZNF404 ZNF331 ZNF836 ZNF182 ZNF497 ZNF334 ZNF732 ZNF197 ZNF778 ZNF649 ZNF160 ZNF564 ZNF445 | 4.04e-30 | 314 | 106 | 31 | PF13912 |
| Domain | SCAN | ZSCAN4 ZKSCAN5 ZNF197 ZNF287 ZNF445 | 1.63e-05 | 56 | 106 | 5 | SM00431 |
| Domain | SCAN_BOX | ZSCAN4 ZKSCAN5 ZNF197 ZNF287 ZNF445 | 1.93e-05 | 58 | 106 | 5 | PS50804 |
| Domain | SCAN | ZSCAN4 ZKSCAN5 ZNF197 ZNF287 ZNF445 | 1.93e-05 | 58 | 106 | 5 | PF02023 |
| Domain | SCAN_dom | ZSCAN4 ZKSCAN5 ZNF197 ZNF287 ZNF445 | 1.93e-05 | 58 | 106 | 5 | IPR003309 |
| Domain | Retrov_capsid_C | ZSCAN4 ZKSCAN5 ZNF197 ZNF287 ZNF445 | 2.10e-05 | 59 | 106 | 5 | IPR008916 |
| Domain | Aminotrans_3 | OAT AGXT2 | 3.16e-04 | 5 | 106 | 2 | IPR005814 |
| Domain | Aminotran_3 | OAT AGXT2 | 3.16e-04 | 5 | 106 | 2 | PF00202 |
| Domain | AA_TRANSFER_CLASS_3 | OAT AGXT2 | 3.16e-04 | 5 | 106 | 2 | PS00600 |
| Pathway | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | ZNF717 ZNF133 ZNF136 ZNF234 ZNF155 ZNF493 ZNF473 ZNF337 ZNF875 KMT5A ZNF180 ZNF485 ZNF223 ZNF224 ZNF225 YY1 ZIM3 ZKSCAN5 ZNF248 ZNF2 ZNF331 ZNF563 ZNF599 ZNF610 ZNF33A ZNF334 ZNF732 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 3.10e-19 | 1387 | 75 | 38 | M734 |
| Pathway | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | ZNF136 ZNF493 ZNF473 KMT5A ZNF180 ZNF780B ZKSCAN5 ZNF284 ZNF248 ZNF2 ZNF563 ZNF836 ZNF610 ZNF778 ZNF664 ZNF160 ZNF445 | 4.14e-07 | 768 | 75 | 17 | MM14851 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS | ZNF136 ZNF224 ZNF331 ZNF610 ZNF33A ZNF778 ZNF649 TASOR | 8.31e-07 | 142 | 75 | 8 | M48257 |
| Pathway | REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION | ZNF136 POLR1A ZNF224 ZNF331 ZNF610 ZNF33A ZNF778 ZNF649 TASOR KDM6A | 8.96e-07 | 254 | 75 | 10 | M27131 |
| Pathway | REACTOME_GENE_EXPRESSION_TRANSCRIPTION | ZNF136 POLR1A ZNF493 ZNF473 KMT5A ZNF180 ZNF780B ZKSCAN5 ZNF284 ZNF248 ZNF2 ZNF563 ZNF836 ZNF610 ZNF778 ZNF664 ZNF160 KDM6A ZNF445 | 1.09e-06 | 1022 | 75 | 19 | MM15436 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS | ZNF136 ZNF224 ZNF331 ZNF610 ZNF33A ZNF778 ZNF649 | 1.55e-06 | 107 | 75 | 7 | M48260 |
| Pubmed | Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. | ZNF234 ZNF155 ZNF180 ZNF223 ZNF224 ZNF225 ZNF229 ZNF284 ZNF404 ZNF222 | 1.43e-20 | 20 | 112 | 10 | 12743021 |
| Pubmed | Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells. | ZNF136 ZNF493 ZNF485 ZNF229 ZNF563 ZNF7 ZNF182 ZNF33A ZNF197 ZNF778 ZNF649 ZNF160 ZNF564 ZNF445 | 9.90e-16 | 181 | 112 | 14 | 37372979 |
| Pubmed | Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. | ZNF493 ZNF7 ZNF836 ZNF610 ZNF778 ZNF160 ZNF287 ZNF445 | 3.62e-12 | 49 | 112 | 8 | 9630514 |
| Pubmed | Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. | ZNF473 VEZF1 PATZ1 ZNF180 ZNF236 ZNF623 YY1 ZNF2 ZNF7 ZNF836 ZNF610 ZNF334 ZNF160 KDM6A ZNF654 ZNF445 | 7.43e-09 | 808 | 112 | 16 | 20412781 |
| Pubmed | Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease. | ZNF133 ZNF234 ZNF473 OAT NCKAP5 ZNFX1 ZNF224 CMYA5 ZNF251 ZKSCAN5 STAB1 ZNF331 ZNF7 ZNF836 ZNF334 ZNF197 ZNF528 CKAP2 KDM6A | 2.87e-08 | 1285 | 112 | 19 | 35914814 |
| Pubmed | Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. | ZNF133 ZNF136 ZNF142 ZNF155 | 2.35e-07 | 17 | 112 | 4 | 7557990 |
| Pubmed | A GO catalogue of human DNA-binding transcription factors. | ZNF234 ZNF155 ZNF223 ZNF654 ZNF222 | 2.45e-07 | 42 | 112 | 5 | 34673265 |
| Pubmed | Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7. | ZNF155 ZNF223 ZKSCAN5 | 1.13e-06 | 7 | 112 | 3 | 8617494 |
| Pubmed | The DNA sequence and biology of human chromosome 19. | ZNF155 ZNF180 ZNF780B ZNF225 ZNF229 ZNF865 CD22 ZNF222 | 4.09e-06 | 284 | 112 | 8 | 15057824 |
| Pubmed | Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma. | CACNA1D KCNJ5 | 1.03e-05 | 2 | 112 | 2 | 24866132 |
| Pubmed | Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury. | CACNA1D KCNJ5 | 1.03e-05 | 2 | 112 | 2 | 37593151 |
| Pubmed | Cellular and Genetic Causes of Idiopathic Hyperaldosteronism. | CACNA1D KCNJ5 | 1.03e-05 | 2 | 112 | 2 | 30354720 |
| Pubmed | Identification of breast cancer associated variants that modulate transcription factor binding. | ANKLE1 ZNF404 | 1.03e-05 | 2 | 112 | 2 | 28957321 |
| Pubmed | Distinct roles of Cep192 and Cep152 in acentriolar MTOCs and spindle formation during mouse oocyte maturation. | CEP192 CEP152 | 1.03e-05 | 2 | 112 | 2 | 28970258 |
| Pubmed | Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults. | CACNA1D KCNJ5 | 1.03e-05 | 2 | 112 | 2 | 35779252 |
| Pubmed | Aldosterone-Producing Adenomas: Histopathology-Genotype Correlation and Identification of a Novel CACNA1D Mutation. | CACNA1D KCNJ5 | 3.08e-05 | 3 | 112 | 2 | 28584016 |
| Pubmed | NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone. | CACNA1D KCNJ5 | 3.08e-05 | 3 | 112 | 2 | 28584012 |
| Pubmed | G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. | CACNA1D KCNJ5 | 3.08e-05 | 3 | 112 | 2 | 26831068 |
| Pubmed | Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152. | CEP192 CEP152 | 3.08e-05 | 3 | 112 | 2 | 24277814 |
| Pubmed | KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia. | YY1 KDM6A | 3.08e-05 | 3 | 112 | 2 | 33456567 |
| Pubmed | Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. | CEP192 CEP152 | 3.08e-05 | 3 | 112 | 2 | 23641073 |
| Pubmed | Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | ZNF473 ZNF623 ZKSCAN5 ZNF836 ZNF610 ZNF436 CEP152 ZNF160 TASOR | 3.25e-05 | 493 | 112 | 9 | 15368895 |
| Pubmed | Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | ZNF136 ZNF234 ZNF160 | 4.14e-05 | 21 | 112 | 3 | 7865130 |
| Pubmed | Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. | ZNF836 ZNF610 ZNF778 ZNF160 | 4.32e-05 | 60 | 112 | 4 | 18023262 |
| Pubmed | Positional cloning of cDNAs from the human chromosome 3p21-22 region identifies a clustered organization of zinc-finger genes. | ZNF197 ZNF445 | 6.14e-05 | 4 | 112 | 2 | 7814019 |
| Pubmed | STIL binding to Polo-box 3 of PLK4 regulates centriole duplication. | CEP192 CEP152 | 6.14e-05 | 4 | 112 | 2 | 26188084 |
| Pubmed | Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma. | CACNA1D KCNJ5 | 6.14e-05 | 4 | 112 | 2 | 26351028 |
| Pubmed | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis. | CEP192 CEP152 | 6.14e-05 | 4 | 112 | 2 | 24997597 |
| Pubmed | Identification of differentially expressed genes in mouse spermatogenesis. | ZNF836 ZNF610 ZNF160 | 8.99e-05 | 27 | 112 | 3 | 14581517 |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | ZNF502 POLR1A ZNF473 ZSCAN4 ZNF180 ZNF236 ZNF623 YY1 ZKSCAN5 ZNF2 ZNF436 | 1.28e-04 | 877 | 112 | 11 | 20211142 |
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | ZNF502 FLNA ZNF142 ZNF473 VEZF1 PDLIM7 KMT5A ZNF485 YY1 MGAT2 ZNF436 ZNF664 ZNF160 | 1.36e-04 | 1203 | 112 | 13 | 29180619 |
| Pubmed | Multiple genes encoding zinc finger domains are expressed in human T cells. | ZNF224 ZNF7 ZNF182 | 1.37e-04 | 31 | 112 | 3 | 2288909 |
| Pubmed | Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. | ZNF133 ZNF136 | 1.53e-04 | 6 | 112 | 2 | 7649249 |
| Pubmed | DDB1 Regulates Sertoli Cell Proliferation and Testis Cord Remodeling by TGFβ Pathway. | KMT5A PLEKHA5 | 1.53e-04 | 6 | 112 | 2 | 31779270 |
| Pubmed | High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization. | PATZ1 ZNF2 FEM1A ZNF445 | 2.49e-04 | 94 | 112 | 4 | 16325481 |
| Pubmed | Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. | PCSK5 WDR7 NCKAP5 | 2.73e-04 | 39 | 112 | 3 | 19010793 |
| Pubmed | The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. | KMT5A MTRFR ZNF664 | 3.91e-04 | 44 | 112 | 3 | 20178780 |
| Pubmed | Genome-wide association analysis identifies 13 new risk loci for schizophrenia. | KMT5A PHF7 STAB1 MTRFR | 4.37e-04 | 109 | 112 | 4 | 23974872 |
| Pubmed | Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. | KMT5A YY1 | 4.55e-04 | 10 | 112 | 2 | 12411495 |
| Pubmed | Hundreds of variants clustered in genomic loci and biological pathways affect human height. | PCSK5 ZNF142 NCKAP5 ZNFX1 TASOR | 4.66e-04 | 198 | 112 | 5 | 20881960 |
| Pubmed | The in vivo Interaction Landscape of Histones H3.1 and H3.3. | ZNF136 VEZF1 KMT5A YY1 FSIP2 ANLN RAD54B ZNF649 | 8.07e-04 | 608 | 112 | 8 | 36089195 |
| Pubmed | A Y2H-seq approach defines the human protein methyltransferase interactome. | KMT5A LCA5L ZKSCAN5 ZNF2 ZNF436 ZNF649 | 8.64e-04 | 342 | 112 | 6 | 23455924 |
| Pubmed | Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. | ZNF182 ZNF33A | 9.12e-04 | 14 | 112 | 2 | 2014798 |
| Pubmed | CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion. | CEP192 CEP152 | 9.12e-04 | 14 | 112 | 2 | 32060285 |
| Pubmed | Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. | ZNF7 CSF3R ZNF778 | 1.02e-03 | 61 | 112 | 3 | 8662221 |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | ZNF133 POLR1A ZNF875 FBXL17 CEP192 ZNF236 ZNF248 ZNF331 ZNF33A ZNF528 CKAP2 KDM6A MTARC1 | 1.02e-03 | 1489 | 112 | 13 | 28611215 |
| Pubmed | Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells. | CEP192 CEP152 | 1.20e-03 | 16 | 112 | 2 | 25833693 |
| Pubmed | Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. | RPGRIP1L CEP192 CEP152 CKAP2 | 1.30e-03 | 146 | 112 | 4 | 21399614 |
| Pubmed | Detailed comparative map of human chromosome 19q and related regions of the mouse genome. | ZNF836 ZNF610 ZNF160 | 1.34e-03 | 67 | 112 | 3 | 8812484 |
| Pubmed | Serological detection of cutaneous T-cell lymphoma-associated antigens. | CKAP2 TASOR | 1.52e-03 | 18 | 112 | 2 | 11149944 |
| Pubmed | Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation. | PATZ1 ZNF182 | 1.70e-03 | 19 | 112 | 2 | 26389696 |
| Pubmed | Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. | ZNF7 ZNF778 | 1.88e-03 | 20 | 112 | 2 | 2542606 |
| Pubmed | Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. | ZNF7 ZNF778 | 1.88e-03 | 20 | 112 | 2 | 7479878 |
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | CAMKK1 PATZ1 CEP192 FSIP2 NF1 ANLN PLEKHA5 CEP152 CKAP2 | 1.90e-03 | 861 | 112 | 9 | 36931259 |
| Pubmed | Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. | PCSK5 ZNF142 | 2.07e-03 | 21 | 112 | 2 | 22959728 |
| Pubmed | Characterization and mapping of human genes encoding zinc finger proteins. | ZNF7 ZNF436 | 2.28e-03 | 22 | 112 | 2 | 1946370 |
| Pubmed | The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification. | ZNF136 ZNF649 | 2.28e-03 | 22 | 112 | 2 | 31403225 |
| Pubmed | A census of human transcription factors: function, expression and evolution. | PATZ1 ZNF180 ZNFX1 ZNF236 YY1 ZNF7 ZNF182 ZNF197 ZNF160 | 2.72e-03 | 908 | 112 | 9 | 19274049 |
| Pubmed | Proteomic characterization of the human centrosome by protein correlation profiling. | CEP192 CEP152 | 3.18e-03 | 26 | 112 | 2 | 14654843 |
| Pubmed | Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice. | ZSCAN4 USP17L10 | 3.18e-03 | 26 | 112 | 2 | 35816173 |
| Interaction | TRIM28 interactions | ZNF133 ZNF136 POLR1A ZNF493 VEZF1 ZNF674 ZNF485 ZNF223 ZNF224 ZNF229 ZNF284 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF182 ZNF33A ZNF732 ANLN ZNF197 ZNF778 ZNF649 ZNF160 ZNF564 ZNF287 ZNF445 | 1.35e-08 | 1474 | 109 | 27 | int:TRIM28 |
| Interaction | LTBP2 interactions | ZNF136 ZNF865 ZNF251 ZNF497 ZNF778 ZNF664 ZNF564 | 3.89e-07 | 85 | 109 | 7 | int:LTBP2 |
| Interaction | NOTCH2 interactions | ZNF136 ZNF142 VEZF1 PATZ1 FBXL17 ZNF623 ZNF865 ZNF7 ZNF497 ZNF664 ZNF649 ZNF445 | 3.13e-06 | 423 | 109 | 12 | int:NOTCH2 |
| Interaction | TRIM41 interactions | RPGRIP1L ZNF473 PHF7 ZNF223 ZNF251 ZNF2 ZNF497 ZNF648 ZNF564 | 3.46e-06 | 223 | 109 | 9 | int:TRIM41 |
| Interaction | CCDC136 interactions | LCA5L ZNF223 ZNF865 ZNF599 ZNF497 ZNF648 ZNF197 ZNF564 | 3.83e-06 | 169 | 109 | 8 | int:CCDC136 |
| Interaction | KRTAP10-7 interactions | PCSK5 ZNF133 ZNF155 ZNF337 ZNF180 ZNF223 ZNF491 ZNF2 ZNF778 ZNF564 | 4.34e-06 | 293 | 109 | 10 | int:KRTAP10-7 |
| Interaction | KRTAP10-9 interactions | PCSK5 ZNF155 ZNF473 YY1 ZNF251 ZNF491 ZNF599 ZNF497 ZNF564 | 6.50e-06 | 241 | 109 | 9 | int:KRTAP10-9 |
| Interaction | LRP4 interactions | ZNF224 ZNF248 ZNF331 ZNF563 ZNF778 | 7.80e-05 | 81 | 109 | 5 | int:LRP4 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | ZNF234 ZNF155 ZNF473 ZNF875 ZSCAN4 ZNF180 ZNF780B ZNF223 ZNF224 ZNF225 ZNF229 ZNF865 ZIM3 ZNF284 ZNF404 ZNF331 ZNF599 SCAF1 ZNF836 ZNF610 ZNF497 CD22 ZNF528 ZNF649 ZNF160 ZNF222 | 1.09e-17 | 1192 | 112 | 26 | chr19q13 |
| Cytoband | 19q13.31 | ZNF234 ZNF229 ZNF284 ZNF404 | 7.60e-07 | 29 | 112 | 4 | 19q13.31 |
| Cytoband | 19q13.2 | ZNF180 ZNF780B ZNF223 ZNF224 ZNF225 ZNF222 | 3.32e-06 | 164 | 112 | 6 | 19q13.2 |
| Cytoband | 12q24.31 | KMT5A CCDC62 MTRFR ZNF664 | 4.60e-05 | 80 | 112 | 4 | 12q24.31 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3p21 | ZNF502 CACNA1D PHF7 STAB1 ZNF197 ZNF445 | 1.32e-04 | 316 | 112 | 6 | chr3p21 |
| Cytoband | 10p11.2 | ZNF248 ZNF33A | 1.64e-04 | 8 | 112 | 2 | 10p11.2 |
| Cytoband | 19q13.41 | ZNF836 ZNF610 ZNF649 | 9.41e-04 | 78 | 112 | 3 | 19q13.41 |
| Cytoband | Xp21.3 | DCAF8L2 DCAF8L1 | 2.29e-03 | 29 | 112 | 2 | Xp21.3 |
| Cytoband | 3p14.3 | CACNA1D TASOR | 2.45e-03 | 30 | 112 | 2 | 3p14.3 |
| Cytoband | 19p13.2 | ZNF136 ZNF491 ZNF563 ZNF564 | 2.46e-03 | 229 | 112 | 4 | 19p13.2 |
| Cytoband | 19q13.42 | ZNF865 ZNF331 ZNF160 | 3.62e-03 | 125 | 112 | 3 | 19q13.42 |
| Cytoband | 3p21.1 | PHF7 STAB1 | 4.77e-03 | 42 | 112 | 2 | 3p21.1 |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | ZNF502 ZNF717 ZNF133 ZNF136 ZNF142 ZNF234 ZNF155 ZNF493 ZNF473 VEZF1 ZNF337 PATZ1 ZNF875 ZSCAN4 ZNF674 ZNF180 ZNF780B ZNF485 ZNF223 ZNF224 ZNF225 ZNF229 ZNF236 ZNF623 ZNF865 YY1 ZNF251 ZIM3 ZKSCAN5 ZNF491 ZNF284 ZNF404 ZNF248 ZNF2 ZNF331 ZNF563 ZNF7 ZNF599 ZNF836 ZNF182 ZNF610 ZNF497 ZNF33A ZNF334 ZNF732 ZNF648 ZNF436 ZNF197 ZNF778 ZNF528 ZNF664 ZNF649 ZNF160 ZNF564 ZNF287 ZNF222 ZNF445 | 9.98e-59 | 718 | 87 | 57 | 28 |
| Coexpression | ZWANG_DOWN_BY_2ND_EGF_PULSE | ZNF717 ZNF493 ZNF875 ZNF780B ZNF225 ZKSCAN5 ZNF33A ZNF732 MTRFR ZNF564 ZNF287 | 9.40e-08 | 321 | 108 | 11 | M2615 |
| Coexpression | GSE2706_UNSTIM_VS_2H_LPS_DC_UP | ZNF493 ZNF473 ZNF224 ZNF284 ZNF7 MTRFR ZNF564 | 1.79e-05 | 197 | 108 | 7 | M4695 |
| Disease | Auriculo-Ventricular Dissociation | CACNA1D KCNJ5 | 7.21e-05 | 4 | 103 | 2 | C0004331 |
| Disease | Heart Block | CACNA1D KCNJ5 | 7.21e-05 | 4 | 103 | 2 | C0018794 |
| Disease | Sick Sinus Syndrome | CACNA1D KCNJ5 | 1.79e-04 | 6 | 103 | 2 | C0037052 |
| Disease | Adenoma, Microcystic | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205648 |
| Disease | Adenoma, Monomorphic | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205649 |
| Disease | Adenoma, Basal Cell | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205646 |
| Disease | Follicular adenoma | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205647 |
| Disease | Papillary adenoma | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205650 |
| Disease | Adenoma, Trabecular | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0205651 |
| Disease | Adenoma | CACNA1D NF1 KCNJ5 | 2.71e-04 | 36 | 103 | 3 | C0001430 |
| Disease | age at onset, multiple sclerosis | PCSK5 NCKAP5 | 5.33e-04 | 10 | 103 | 2 | EFO_0004847, MONDO_0005301 |
| Disease | atrial fibrillation (is_implicated_in) | AGXT2 KCNJ5 | 1.07e-03 | 14 | 103 | 2 | DOID:0060224 (is_implicated_in) |
| Disease | Sinus Node Dysfunction (disorder) | CACNA1D KCNJ5 | 1.23e-03 | 15 | 103 | 2 | C0428908 |
| Disease | apolipoprotein B measurement | PCSK5 ZNF180 ZNF224 ZNF229 ZNF284 ZNF404 NF1 ZNF664 | 2.28e-03 | 663 | 103 | 8 | EFO_0004615 |
| Disease | stem Cell Growth Factor beta measurement | PCSK5 ZNF563 ZNF197 | 2.32e-03 | 75 | 103 | 3 | EFO_0008292 |
