Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionheparan sulfate N-deacetylase activity

NDST1 NDST3

1.20e-0431272GO:0102140
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST1 NDST3

2.39e-0441272GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST1 NDST3

2.39e-0441272GO:0050119
GeneOntologyCellularComponentcytoplasmic region

PCLO GAS8 AMBRA1 SEPTIN2 SPTBN5 KIF3C KIF5C DNAAF1 DNAH5 HTT

6.22e-0536012510GO:0099568
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

GAS8 AMBRA1 SEPTIN2 SPTBN5 KIF3C KIF5C DNAAF1 DNAH5 HTT

1.24e-043171259GO:0032838
GeneOntologyCellularComponentmicrotubule organizing center

SLAIN2 VPS37A GAS8 SFI1 SPECC1L HNMT FRY NDRG1 ATM TNKS2 SCLT1 ZBED1 MTUS2 WDR62 HTT

3.93e-0491912515GO:0005815
DomainZINC_FINGER_C2H2_1

BNC2 HIC1 ZBTB17 ZNF280D ZNF618 ZNF521 ZNF280B POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 CIZ1 ZNF749 SUZ12

1.21e-0577712217PS00028
DomainZnf_C2H2-like

BNC2 HIC1 ZBTB17 ZNF280D ZNF618 ZNF521 ZNF280B POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 CIZ1 ZNF749 SUZ12

1.65e-0579612217IPR015880
DomainZnF_C2H2

BNC2 HIC1 ZBTB17 ZNF280D ZNF618 ZNF521 ZNF280B POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 CIZ1 ZNF749 SUZ12

1.99e-0580812217SM00355
DomainZINC_FINGER_C2H2_2

BNC2 HIC1 ZBTB17 ZNF280D ZNF618 ZNF521 ZNF280B POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 ZNF749 SUZ12

4.48e-0577512216PS50157
DomainZnf_C2H2

BNC2 HIC1 ZBTB17 ZNF280D ZNF618 ZNF521 ZNF280B POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 CIZ1 ZNF749

7.02e-0580512216IPR007087
DomainHeparan_SO4_deacetylase

NDST1 NDST3

2.52e-0441222IPR021930
DomainDUF4195

ZNF280D ZNF280B

2.52e-0441222IPR025243
DomainDUF4195

ZNF280D ZNF280B

2.52e-0441222PF13836
DomainHSNSD

NDST1 NDST3

2.52e-0441222PF12062
DomainSpectrin

DRP2 SPTB SPTBN5

4.38e-04231223PF00435
Domainzf-C2H2

BNC2 HIC1 ZBTB17 ZNF280D ZNF521 POGZ ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 ZNF749

6.04e-0469312213PF00096
DomainSpectrin_repeat

DRP2 SPTB SPTBN5

8.78e-04291223IPR002017
Domainzf-TRAF

TRAF7 PDZRN3

1.15e-0381222PF02176
DomainCalx_beta

FRAS1 FREM3

1.15e-0381222SM00237
DomainSPEC

DRP2 SPTB SPTBN5

1.17e-03321223SM00150
DomainSpectrin/alpha-actinin

DRP2 SPTB SPTBN5

1.17e-03321223IPR018159
DomainCalx_beta

FRAS1 FREM3

1.48e-0391222IPR003644
DomainCalx-beta

FRAS1 FREM3

1.48e-0391222PF03160
DomainKinesin_motor_CS

KIF3C KIF5C KIF11

2.42e-03411223IPR019821
DomainZnf_TRAF

TRAF7 PDZRN3

2.68e-03121222IPR001293
DomainGRIP_dom

TRIP11 GOLGA4

2.68e-03121222IPR000237
DomainGRIP

TRIP11 GOLGA4

2.68e-03121222PS50913
DomainKinesin-like_fam

KIF3C KIF5C KIF11

2.77e-03431223IPR027640
Domain-

KIF3C KIF5C KIF11

2.96e-034412233.40.850.10
DomainKinesin

KIF3C KIF5C KIF11

2.96e-03441223PF00225
DomainKISc

KIF3C KIF5C KIF11

2.96e-03441223SM00129
DomainKINESIN_MOTOR_1

KIF3C KIF5C KIF11

2.96e-03441223PS00411
DomainKinesin_motor_dom

KIF3C KIF5C KIF11

2.96e-03441223IPR001752
DomainKINESIN_MOTOR_2

KIF3C KIF5C KIF11

2.96e-03441223PS50067
DomainZF_TRAF

TRAF7 PDZRN3

3.15e-03131222PS50145
Domain-

TRAF7 PDZRN3

3.66e-031412223.90.890.10
DomainFerritin-like_SF

MOB1A COQ7

3.66e-03141222IPR009078
DomainSIAH-type

TRAF7 PDZRN3

4.78e-03161222IPR013323
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NDST1 PTGES2 DCAF6 WAPL DNAJA2 SPTB ZNF521 POGZ TRIP12 TRIP11 SEPTIN2 NEFM FRY NDRG1 CTR9 OSBPL1A RNF38 CD74 EXOC1 ATM KIF5C TNKS2 MTUS2 CAP2

4.36e-1112851272435914814
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ZNF618 DNAJA2 SPECC1L TRIP11 ZBTB1 SEPTIN2 NEFM FRY PBRM1 SPHKAP DGKI KIF5C BUB3 CNOT1 GOLGA4 GOLGB1 CAP2 KIF11

1.50e-089631271828671696
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

WAPL ZNF280D POLE PCLO DNAJA2 POGZ IDH3B SEPTIN2 CKB JARID2 PBRM1 CTR9 UTP20 KIF3C ATM SUZ12 BUB3 DNAH5 CNOT1 GOLGA4 KIF11

5.11e-0814251272130948266
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

ADCY10 DOCK10 SPECC1L CKB TRPM1 DNAH5 CNOT1 GOLGB1 KIF11

7.93e-08208127933230847
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TRAF7 SLAIN2 DCAF6 WAPL ZNF618 DNAJA2 AMBRA1 POGZ IDH3B ZNF526 PBRM1 CIZ1 SDF4 SUZ12 ANKRD52 PDZRN3 WDR62

6.94e-0711161271731753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO TAB2 SPECC1L CTR9 KIF5C MTUS2

8.34e-0787127612465718
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

TAB2 ZNF490 NEFM ZNF17 EXOC1 KIF3C GOLGA4

1.46e-06151127717043677
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TRMT9B DCAF6 VPS37A NRF1 SPTB ZSWIM6 TSNAX ZHX2 NPLOC4 NDRG1 KIF5C MBD5 NFAT5 CNOT1 GOLGA4 GOLGB1 CAP2 HTT XPO7

2.04e-0614891271928611215
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF280D ICE1 POGZ ZBTB1 NEFM ANKRD52 CNOT1 GOLGB1 WDR62 KIF11

3.39e-064181271034709266
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

PBRM1 CTR9 SUZ12 MED17 CNOT1

5.59e-0669127528481362
Pubmed

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

COL6A3 FRAS1 FREM3

5.60e-0610127315345741
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

WAPL DNAJA2 IDH3B SEPTIN2 PBRM1 CNOT1 KIF11

1.03e-05203127722083510
Pubmed

Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation.

ADCY10 NOS3

1.32e-052127216144836
Pubmed

Re-routing of the invariant chain to the direct sorting pathway by introduction of an AP3-binding motif from LIMP II.

SCARB2 CD74

1.32e-052127216542748
Pubmed

Dual-functional significance of ATM-mediated phosphorylation of spindle assembly checkpoint component Bub3 in mitosis and the DNA damage response.

ATM BUB3

1.32e-052127235085551
Pubmed

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

ATM HTT

1.32e-052127225540325
Pubmed

Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease.

CKB HTT

1.32e-052127221403395
Pubmed

Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.

ATM HTT

1.32e-052127228017939
Pubmed

Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.

ATM HTT

1.32e-052127224277524
Pubmed

Ataxia telangiectasia-mutated, a DNA damage-inducible kinase, contributes to high NaCl-induced nuclear localization of transcription factor TonEBP/OREBP.

ATM NFAT5

1.32e-052127215840767
Pubmed

Phosphorylation of HIC1 (Hypermethylated in Cancer 1) Ser694 by ATM is essential for DNA repair.

HIC1 ATM

1.32e-052127233756345
Pubmed

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.

NRF1 ATM

1.32e-052127230642892
Pubmed

Heparin cofactor II, a serine protease inhibitor, promotes angiogenesis via activation of the AMP-activated protein kinase-endothelial nitric-oxide synthase signaling pathway.

SERPIND1 NOS3

1.32e-052127222904320
Pubmed

ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

ATM NFAT5

1.32e-052127215173573
Pubmed

A central role of TRAX in the ATM-mediated DNA repair.

TSNAX ATM

1.32e-052127226096928
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

WAPL DNAJA2 POGZ TRIP12 PBRM1 CIZ1 SUZ12 CNOT1 KIF11

1.53e-05394127927248496
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRAF7 PCLO DNAJA2 JARID2 PBRM1 SDF4 TRPM1 SUZ12 KIF11

1.60e-05396127926687479
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

PCLO POGZ ZHX2 PBRM1 CIZ1 SUZ12 TNKS2 MVK KIF11

1.66e-05398127935016035
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 DOCK10 POGZ ZSWIM6 ZHX2 SPHKAP SUZ12 NFAT5 XPO7

1.98e-05407127912693553
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SLAIN2 WAPL AMBRA1 ICE1 POGZ SFI1 NPLOC4 SEPTIN2 FTO CNOT1

2.60e-055291271014621295
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

POLE POGZ TRIP12 CKB NEFM PBRM1 UTP20 ATM ANKRD52 CNOT1 XPO7

2.92e-056531271122586326
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

STARD13 WAPL POLE DNAJA2 DOCK10 AMBRA1 POGZ IDH3B TRIP12 CTR9 UTP20 EXOC1 BUB3 ANKRD52 GOLGA4 KIF11

3.55e-0513531271629467282
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SLAIN2 WAPL POGZ SPECC1L NEFM CIZ1 BUB3 MED17 CNOT1 HTT

3.56e-055491271038280479
Pubmed

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

TRIP12 TRIP11 KIF11

3.73e-051812737776974
Pubmed

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

ICE1 JARID2 SUZ12

3.73e-0518127320064376
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TRMT9B SLAIN2 FRAS1 NPLOC4 MBD5

3.94e-05103127510819331
Pubmed

Racial Disparities in Methylation of NRF1, FTO, and LEPR Gene in Childhood Obesity.

NRF1 FTO

3.96e-053127236360268
Pubmed

PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells.

JARID2 SUZ12

3.96e-053127223333148
Pubmed

Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.

NDST1 NDST3

3.96e-05312729915799
Pubmed

Evaluation of the possible association of body mass index and four metabolic gene polymorphisms with longevity in an Italian cohort: a role for APOE, eNOS and FTO gene polymorphisms.

FTO NOS3

3.96e-053127231446792
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FRAS1 FREM3

3.96e-053127221993971
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

WAPL TSNAX IDH3B CTR9 SCARB2 EXOC1 SUZ12 MED17 CNOT1 KIF11

4.20e-055601271035241646
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

TAB2 SEPTIN2 CKB SDF4 EXOC1 KIF3C KIF5C BUB3 NFAT5 CNOT1 WDR62 KIF11

4.33e-058091271232129710
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

POLE ICE1 SPECC1L ZHX2 ZBTB1 SDF4 ATM BUB3 MED17

4.55e-05453127929656893
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

HIC1 NDRG1 SPHKAP SUZ12 SERPIND1 GOLGB1 WDR62

4.66e-05257127730945288
Pubmed

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.

KIF5C MED17 WDR62

5.18e-0520127336551904
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

WAPL POLE SFI1 TRIP12 EXOC1 ATM BUB3 CNOT1 GOLGB1 KIF11

5.79e-055821271020467437
Pubmed

Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.

SLAIN2 DNAJA2 TAB2 TEX15 OSBPL1A KIF11

6.15e-05184127623402259
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

COL6A3 ZNF618 SPTB SPTBN5 NEFM KIF11

6.72e-05187127626460568
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SLAIN2 DNAJA2 TAB2 CKB NDRG1 ARHGAP29 KIF5C SCLT1 ANKRD52 CNOT1 PDZRN3 WDR62

7.17e-058531271228718761
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

TRAF7 DCAF6 WAPL MAN2B1 TAB2 MOB1A KIF3C ZBED1

7.88e-05378127834315543
Pubmed

Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.

NDST1 NDST3

7.90e-054127222049073
Pubmed

Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.

FRAS1 FREM3

7.90e-054127218563433
Pubmed

Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses.

NDST1 NDST3

7.90e-054127216056228
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FRAS1 FREM3

7.90e-054127224101214
Pubmed

Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.

NDST1 NDST3

7.90e-054127212070138
Pubmed

Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation.

NDST1 NDST3

7.90e-054127229688404
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ZNF618 PCLO CST11 ICE1 SLFN5 TRIP12 IGSF10 FRY UTP20 ATM CNOT1

8.53e-057361271129676528
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

STARD13 NRF1 AMBRA1 TRIP11 NEFM CTR9 OSBPL1A CIZ1 EXOC1 KIF3C KIF5C BUB3 DNAAF1 CNOT1 WDR62

9.94e-0513211271527173435
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF3C KIF5C KIF11

1.03e-042512739275178
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

DRP2 POLE TAB2 IDH3B TRIP11 PBRM1 MED17 DNAAF1 ANKRD52 CNOT1

1.23e-046381271031182584
Pubmed

Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex.

GAS8 DNAH5

1.31e-045127226387594
Pubmed

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

FRAS1 FREM3

1.31e-045127217251066
Pubmed

Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.

NDST1 NDST3

1.31e-045127211087757
Pubmed

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

FRAS1 FREM3

1.31e-045127217596926
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

WAPL POGZ TRIP12 NDRG1 CTR9 UTP20 ATM SUZ12 BUB3 GOLGA4 WDR62

1.33e-047741271115302935
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

WAPL SPECC1L TRIP12 TRIP11 MED17 ANKRD52

1.34e-04212127633853758
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FRAS1 WAPL MAN2B1 POLE DOCK10 AMBRA1 NPLOC4 CTR9 ZBED1 RBM47

1.43e-046501271038777146
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

WAPL ICE1 TSNAX TRIP11 NPLOC4 SEPTIN2 CKB NDRG1 CIZ1 GOLGB1 WDR62 KIF11

1.67e-049341271233916271
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

WAPL NFKBIZ TAB2 TSNAX TRIP12 CTR9 RNF38 SDF4 NFAT5 SUCO CNOT1 GOLGB1 KIF11

1.75e-0410841271311544199
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

BNC2 ZBTB17 ZNF280D NFKBIZ ZNF280B POGZ ZUP1 JARID2 PBRM1 CIZ1 NFAT5

1.92e-048081271120412781
Pubmed

EZH2 K63-polyubiquitination affecting migration in extranodal natural killer/T-cell lymphoma.

TRIP12 SUZ12

1.97e-046127238031139
Pubmed

Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins.

HIC1 SUZ12

1.97e-046127222315224
Pubmed

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

JARID2 SUZ12

1.97e-046127227892467
Pubmed

Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.

PCLO PBRM1

1.97e-046127225636086
Pubmed

Digital quantification of human eye color highlights genetic association of three new loci.

LYST NPLOC4

1.97e-046127220463881
Pubmed

Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.

FRAS1 FREM3

1.97e-046127217462874
Pubmed

Nitric-oxide synthase 2 interacts with CD74 and inhibits its cleavage by caspase during dendritic cell development.

CD74 NOS3

1.97e-046127218003616
Pubmed

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.

JARID2 SUZ12

1.97e-046127220064375
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRAF7 NDST1 FRAS1 MAN2B1 NRF1 POLE AMBRA1 ICE1 SFI1 LYST SDF4 MBD5 HTT

2.10e-0411051271335748872
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CCDC110 DNAJA2 GAS8 CKB NEFM SDF4 EXOC1 GOLGA4 GOLGB1

2.37e-04564127921565611
Pubmed

A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype.

TRIP11 NEFM

2.75e-047127221214893
Pubmed

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

PBRM1 FTO

2.75e-047127222763110
Pubmed

Altered heparan sulfate structure in mice with deleted NDST3 gene function.

NDST1 NDST3

2.75e-047127218385133
Pubmed

Jarid2 and PRC2, partners in regulating gene expression.

JARID2 SUZ12

2.75e-047127220123894
Pubmed

ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.

NPLOC4 ATM

2.75e-047127234144977
Pubmed

Jarid2 regulates mouse epidermal stem cell activation and differentiation.

JARID2 SUZ12

2.75e-047127221811233
Pubmed

Mediator CDK subunits are platforms for interactions with various chromatin regulatory complexes.

SUZ12 MED17

2.75e-047127222668559
Pubmed

BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.

DNAJA2 IDH3B BUB3 CNOT1 WDR62

2.79e-04156127532850835
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DCAF6 MAN2B1 TSNAX NPLOC4 SEPTIN2 CKB NDRG1 CTR9 FTO BUB3 CNOT1 MVK CAP2 HTT XPO7

2.83e-0414551271522863883
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

AMBRA1 ICE1 TSNAX TRIP12 NPLOC4 CKB SDF4 BUB3 SCLT1 ANKRD52 CNOT1 KIF11

3.26e-0410051271219615732
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 TAB2 TRIP12 TRIP11 LYST NDRG1 KIF5C GOLGA4 GOLGB1 WDR62 KIF11

3.30e-048611271136931259
Pubmed

Functional proteomics mapping of a human signaling pathway.

STARD13 MAN2B1 TRIP12 PBRM1 CTR9 SDF4 TNKS2 GOLGB1 CAP2

3.34e-04591127915231748
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

POLE NFKBIZ TRIP12 JARID2 PBRM1 SUZ12 BUB3 CNOT1

3.41e-04469127827634302
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

COL6A3 LYST LRIG1 FZD10 NOS3

3.41e-04163127535364055
Pubmed

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

ZHX2 LRIG1

3.65e-048127221909108
Pubmed

Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.

STARD13 FRY

3.65e-04812728812419
Pubmed

Huntingtin facilitates polycomb repressive complex 2.

SUZ12 HTT

3.65e-048127219933700
Pubmed

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.

COL6A3 FRAS1

3.65e-048127212766770
Pubmed

K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.

TAB2 NPLOC4

3.65e-048127225752573
Cytoband2q23.1

KIF5C MBD5

1.13e-04612722q23.1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

BNC2 HIC1 ZBTB17 ZNF618 ZNF521 ZHX2 ZBTB1 ZUP1 ZNF490 ZNF17 ZNF526 ZNF749 SUZ12

3.73e-05718871328
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN5

4.73e-0478721113
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF3C KIF5C KIF11

1.41e-0346873622
GeneFamilyWD repeat domain containing

TRAF7 DCAF6 AMBRA1 LYST BUB3 WDR62

1.66e-03262876362
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PCLO NPLOC4

2.31e-031587226
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF6 AMBRA1

3.33e-0318872498
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

STARD13 WAPL TAB2 SPECC1L ZHX2 TRIP12 JARID2 ARHGAP29 KIF5C SUZ12 FTO GOLGA4 CAP2 KIF11

6.45e-0846612714M13522
CoexpressionSHEN_SMARCA2_TARGETS_UP

DCAF6 TAB2 TSNAX HNMT TRIP12 SEPTIN2 CTR9 OSBPL1A ARHGAP29 RNF38 EXOC1 FTO BUB3

1.77e-0742912713M29
CoexpressionMURARO_PANCREAS_BETA_CELL

SLAIN2 VPS37A PCLO DOCK10 TAB2 SPECC1L TRIP11 LYST NEFM NDRG1 KIF5C TNKS2 SUCO DNAH5 PDZRN3 MTUS2 GOLGA4 GOLGB1

7.39e-0794612718M39169
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

STARD13 WAPL TAB2 SPECC1L ZHX2 TRIP12 JARID2 LRIG1 ARHGAP29 UTP20 KIF5C SUZ12 FTO SUCO GOLGA4 CAP2 KIF11

8.63e-0785612717M4500
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

SLAIN2 BNC2 VPS37A WAPL ZBTB17 ZNF280D ZNF618 POLE TAB2 SFI1 COA4 ZBTB1 ZUP1 ZNF490 IGSF10 NEFM JARID2 CTR9 ATM KIF5C SUZ12 MBD5 SCLT1 PDZRN3

2.58e-07125212524facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

BNC2 COL6A3 HIC1 WAPL ZNF521 TEX15 TRIP12 NEFM LRIG1 OSBPL1A FTO TNKS2 NFAT5 SUCO PDZRN3 CAP2

1.67e-0579112516gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SLAIN2 NFKBIZ SLFN5 TRIP12 TRIP11 OSBPL1A SUZ12 DNAH5 GOLGA4 GOLGB1

3.05e-1019912710fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SLAIN2 NFKBIZ SLFN5 TRIP12 TRIP11 OSBPL1A GOLGA4 GOLGB1

1.09e-07199127853ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

SLAIN2 ZNF618 NFKBIZ SLFN5 TRIP12 TRIP11 GOLGB1

1.44e-071381277817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AMBRA1 ZSWIM6 ZHX2 JARID2 DGKI NFAT5 RBM47

1.39e-061931277779276e775cb2492e8dd36436295a536084a6415
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 JARID2 NDRG1 MBD5 NFAT5 GOLGA4 GOLGB1

1.39e-061931277e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SLAIN2 NFKBIZ SLFN5 TRIP12 TRIP11 GOLGA4 GOLGB1

1.70e-06199127761b1ed2db71b96157b92b7535d1955a4033098da
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TRMT9B PCLO PLPPR5 NEFM NDRG1 KIF3C CAP2

1.76e-0620012770cb0755a101ec655359d051d6a8807408d727c55
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

STARD13 AARD CCDC110 DOCK10 SLFN5 HNMT

5.99e-0615712762c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLE SPECC1L SLFN5 TRIP11 FTO ANKRD52

9.12e-0616912765f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 POLE PLPPR5 OAF LRIG1 MTUS2

1.19e-0517712763e149bff1f1b393a7abe98984e37981c8296f95d
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 TRIP11 LYST ZUP1 CD74 SUCO

1.39e-051821276eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DRP2 PCLO SFI1 MYH15 DNAH5

1.48e-0518412762cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 NFKBIZ SLFN5 TRIP11 LYST GOLGA4

1.48e-0518412761154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DRP2 PCLO SFI1 MYH15 DNAH5

1.48e-051841276ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DRP2 PCLO SFI1 MYH15 DNAH5

1.48e-0518412762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 COL6A3 ZNF521 NDST3 KLK8 SERPIND1

1.53e-051851276ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-2|TCGA-Bladder / Sample_Type by Project: Shred V9

BNC2 DRP2 ZNF521 CST11 PCDHB18P

1.67e-051111275aeb2c06beda62f9a79fc73788dd1c5cf9a2f35fe
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRMT9B FRAS1 CCDC110 NDST3 NEFM

1.67e-0511112751847dde68d349114286bc3317be6339666df4aa2
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 TEX15 FREM3 IGSF10 LRIG1 PDZRN3

1.77e-051901276c7bd087f36321cec61b98657433b4d19d135791f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 TEX15 FREM3 IGSF10 LRIG1 PDZRN3

1.77e-051901276834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 PLPPR5 NEFM JARID2 KIF5C BUB3

1.88e-051921276d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 JARID2 NDRG1 MBD5 NFAT5 GOLGA4

1.88e-051921276916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIC1 SLFN5 LYST ZBTB1 BUB3 DTHD1

1.88e-051921276189477c44040cf0ee16c3932fa49fbd9e3acaa3c
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 PLPPR5 NEFM JARID2 KIF5C BUB3

1.94e-0519312769661ea0ee7273928c7de2a9f49e853595fa77699
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 ZNF521 LYST NDRG1 ARHGAP29 NOS3

2.05e-05195127681a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO CKB SPHKAP TNKS2 GOLGA4 GOLGB1

2.05e-0519512763e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO TRIP11 CKB SPHKAP GOLGA4 GOLGB1

2.05e-0519512767796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.11e-051961276676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL6A3 FRAS1 DOCK10 PLPPR5 IGSF10 SPHKAP

2.17e-0519712760034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.24e-051981276c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.24e-0519812766d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.24e-0519812768ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

NFKBIZ SLFN5 TRIP11 SUZ12 GOLGA4 GOLGB1

2.24e-05198127676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.24e-0519812760ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BNC2 SFI1 ATM DTHD1 GOLGA4 GOLGB1

2.30e-051991276f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 AMBRA1 ZSWIM6 ZHX2 FTO MBD5

2.30e-05199127694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

SLAIN2 PCLO SLFN5 TRIP11 GOLGA4 GOLGB1

2.30e-051991276c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

SLAIN2 NFKBIZ SLFN5 TRIP11 GOLGA4 GOLGB1

2.30e-051991276d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

PCLO FRY DGKI KIF5C MTUS2 CAP2

2.37e-05200127648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NFKBIZ SLFN5 TRIP12 ATM GOLGA4 GOLGB1

2.37e-05200127612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK10 RNF38 ATM SUZ12 MED17

2.74e-051231275511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FRAS1 NEFM CD74 DNAH5 PDZRN3

9.02e-051581275c8af8964a140acb2987e3b4906d72c546108d229
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 NFKBIZ TEX15 LYST XPO7

1.08e-041641275f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

WAPL DOCK10 TAB2 SCARB2 GOLGB1

1.17e-041671275ced6ed9b412739c6ced622523347c10295edbf53
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 PCLO KLK8 RASL10B RBM47

1.20e-041681275e870d2e69316406f45112ed0bf324b24f902a99e
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

STARD13 BNC2 ZHX2 SERPIND1 NOS3

1.20e-041681275c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 PCLO KLK8 RASL10B RBM47

1.20e-041681275403aba73a0f9ffb32252288d075fad8a588ca440
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PCLO DGKI MYH15 DNAH5

1.24e-04169127512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 SLFN5 CKB PTCHD1 CD74

1.27e-041701275545c755b057871b7a22221a049a63a61713dad1d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 SPTB DGKI SUCO DNAH5

1.27e-04170127517bd7fd25a2657cb536ad47e294332920f759e95
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 HIC1 MYH15 WDR62 KIF11

1.31e-041711275b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 HIC1 MYH15 WDR62 KIF11

1.31e-041711275b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellHealthy_donor-MAIT|World / disease group, cell group and cell class (v2)

CCDC110 ZBTB1 KIF5C RASL10B CAP2

1.34e-0417212756524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 COL6A3 ZNF521 DGKI PDZRN3

1.38e-0417312751f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 PCLO KLK8 DGKI RASL10B

1.38e-041731275e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 PCLO KLK8 DGKI RASL10B

1.38e-04173127574ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CCDC110 ZNF521 OAF ARHGAP29 FZD10

1.38e-041731275a81992965137195d20fc498f750975303961a828
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TRMT9B PCLO OTUD3 WDR62 KIF11

1.46e-041751275fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB DGKI FZD10 SUCO DNAH5

1.46e-041751275f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCelldroplet-Liver-Npc-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 DOCK10 SLFN5 CKB CD74

1.46e-04175127592a4a3fd323ee8360edd659f9e16dfddc8788e2f
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

TRMT9B PCLO OTUD3 WDR62 KIF11

1.46e-04175127536c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAN2B1 DOCK10 CKB CD74 RBM47

1.50e-0417612757d1e2627d7ec5ddd6c87c55d2a6879255b76949e
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

SFI1 LYST OTUD3 NFAT5 HTT

1.54e-04177127582fdd6185b368f54f03de389427cbe3071d21a99
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL SLFN5 TRIP11 LYST ARHGAP29

1.58e-04178127501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 DGKI KIF3C SUCO DNAH5

1.58e-04178127509a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STARD13 ZNF618 CKB OTUD3 SCLT1

1.62e-041791275163f5430d72ea0c1b239ea5d21e53be536636d3d
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PCLO ZNF521 NDST3 FRY ARHGAP29

1.62e-04179127599777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STARD13 ZNF618 CKB OTUD3 SCLT1

1.62e-0417912750624dd537a68736f4d7b8b4de2c56168ed0e60a9
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 HIC1 DRP2 DGKI PDZRN3

1.66e-041801275935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 HIC1 DRP2 DGKI PDZRN3

1.66e-0418012753dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPTB FRY SPHKAP PDZRN3 MTUS2

1.70e-041811275719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 COL6A3 FRAS1 IGSF10 PDZRN3

1.70e-0418112759ede19228ba5c0668a9c06c915510b95585216ef
ToppCellHealthy_donor-MAIT|Healthy_donor / disease group, cell group and cell class (v2)

CCDC110 ZBTB1 KIF5C RASL10B CAP2

1.75e-041821275ac7c83464487ecde3df6804a99551307bd768f21
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 NFKBIZ SLFN5 TRIP11 LYST

1.75e-041821275f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFM PTCHD1 LRIG1 RASL10B CAP2

1.75e-041821275eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 HIC1 DRP2 DGKI PDZRN3

1.79e-041831275803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 HIC1 DRP2 DGKI PDZRN3

1.79e-0418312756d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 FRAS1 DRP2 PTCHD1 CAP2

1.79e-04183127561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 HIC1 DRP2 DGKI PDZRN3

1.79e-041831275cc7f5a17b40e8d901885174922e5fa8877643071
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 COL6A3 NDST3 SPHKAP PDZRN3

1.79e-04183127512daaea821e49bc94a01e2496331e92a80d27339
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

WAPL NPLOC4 CIZ1 GOLGA4 HTT

1.84e-041841275ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEFM SPHKAP KIF5C MTUS2

1.84e-0418412757d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPTB FRY SPHKAP PDZRN3 MTUS2

1.89e-041851275549eeb521c3985bff396ea0f202db21822efa51f
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

BNC2 COL6A3 ZNF521 OAF PDZRN3

1.89e-041851275fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 COL6A3 DOCK10 SPHKAP PDZRN3

1.89e-0418512753b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 NFKBIZ SLFN5 TRIP11 LYST

1.89e-0418512757adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 SLFN5 LRIG1 ATM DTHD1

1.93e-0418612759d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 SLFN5 LRIG1 ATM DTHD1

1.93e-041861275bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB NDST3 SPHKAP KIF5C RASL10B

1.93e-041861275a1ab273b01971d6a892912560d387685dd657179
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 SLFN5 LRIG1 ATM DTHD1

1.93e-041861275924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB NDST3 SPHKAP KIF5C RASL10B

1.98e-041871275ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NDST3 PTCHD1 SPHKAP KIF5C

1.98e-0418712751b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 FRAS1 NDST3 FRY NDRG1

1.98e-041871275f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

TRMT9B DOCK10 PTCHD1 FRY PDZRN3

2.03e-04188127534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 COL6A3 CKB PDZRN3 CAP2

2.03e-041881275293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRMT9B BNC2 ZHX2 ARHGAP29 DGKI

2.03e-041881275af740fa78542438fdff627ea1f74f4eee43316be
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 CKB NDRG1 KLK8 CAP2

2.03e-041881275e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 FRAS1 FRY NDRG1 NFAT5

2.03e-041881275e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB FRY ARHGAP29 HCFC1R1 CAP2

2.03e-041881275c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

BNC2 ZNF521 JARID2 KIF5C SCLT1

2.08e-0418912753922135d1f6fc768d71ba3b465585fead6ea68a8
DrugLY 294002; Up 200; 10uM; HL60; HT_HG-U133A

TRMT9B PTGES2 AMBRA1 SCARB2 MOB1A MYH15 MVK WDR62 HTT

1.03e-0618612791177_UP
Diseaseintellectual disability (implicated_via_orthology)

NDST1 ZNF280D ZNF280B POGZ NDST3

1.46e-05751215DOID:1059 (implicated_via_orthology)
DiseaseHypertension, Goldblatt

TRIP11 NOS3

1.67e-0521212C0018036
DiseaseMalformations of Cortical Development

NDST1 KIF5C WDR62

2.37e-05141213C1955869
DiseaseCortical Dysplasia

NDST1 KIF5C WDR62

2.37e-05141213C0431380
Diseasehair colour measurement

BNC2 FRAS1 ZBTB17 ZNF618 GAS8 DOCK10 TRIP11 LYST NPLOC4 PTCHD1 FTO

4.75e-0561512111EFO_0007822
Diseaseneck circumference

FTO ANKRD52 PDZRN3

6.21e-05191213EFO_0011043
DiseaseIntellectual Disability

NDST1 POGZ SPECC1L PTCHD1 FRY ZNF526 SUZ12 WDR62 HTT

9.81e-054471219C3714756
DiseaseMacrostomia

FRAS1 SPECC1L

9.95e-0541212C0024433
DiseaseStrabismus

ZNF618 NPLOC4 DNAH5

2.27e-04291213HP_0000486
DiseaseProfound Mental Retardation

NDST1 PTCHD1 FRY ZNF526 WDR62

2.77e-041391215C0020796
DiseaseMental Retardation, Psychosocial

NDST1 PTCHD1 FRY ZNF526 WDR62

2.77e-041391215C0025363
DiseaseMental deficiency

NDST1 PTCHD1 FRY ZNF526 WDR62

2.77e-041391215C0917816
Diseasediet measurement

BNC2 WAPL NRF1 ZNF618 ZNF521 ZSWIM6 TEX15 DGKI FTO MBD5 DNAH5 CNOT1 MVK

3.81e-04104912113EFO_0008111
Diseaseage-related hearing impairment

BNC2 DOCK10 SFI1 NPLOC4 NDRG1 FZD10 FTO

3.91e-043241217EFO_0005782
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST1 ZNF280D ZNF280B POGZ NDST3

4.18e-041521215DOID:0060041 (implicated_via_orthology)
Diseasechronic kidney disease

COL6A3 NDST3 LRIG1 FTO NFAT5 PDZRN3

4.29e-042351216EFO_0003884
DiseasePrimary ciliary dyskinesia

GAS8 DNAAF1 DNAH5

4.35e-04361213cv:C0008780
DiseaseDystonia

COL6A3 VPS37A CIZ1 ATM

4.41e-04861214C0013421
Diseasecleft palate (implicated_via_orthology)

SPECC1L GOLGB1

4.59e-0481212DOID:674 (implicated_via_orthology)
DiseaseParoxysmal atrial fibrillation

LRIG1 KIF3C MBD5 NOS3 XPO7

4.70e-041561215C0235480
Diseasefamilial atrial fibrillation

LRIG1 KIF3C MBD5 NOS3 XPO7

4.70e-041561215C3468561
DiseasePersistent atrial fibrillation

LRIG1 KIF3C MBD5 NOS3 XPO7

4.70e-041561215C2585653
DiseaseFEV/FEC ratio

STARD13 BNC2 COL6A3 FRAS1 NPLOC4 SEPTIN2 SPTBN5 TTC23 RNF38 SUZ12 FTO DTHD1 DNAH5 PDZRN3

5.19e-04122812114EFO_0004713
DiseaseAtrial Fibrillation

LRIG1 KIF3C MBD5 NOS3 XPO7

5.28e-041601215C0004238
Diseasechronic obstructive pulmonary disease

BNC2 COL6A3 FRAS1 DOCK10 FREM3 TTC23 FTO DTHD1 SCLT1 DNAH5

5.53e-0468812110EFO_0000341
Diseasedietary approaches to stop hypertension diet

ZSWIM6 FTO

5.89e-0491212EFO_0803365
Diseaseosteoarthritis, knee, body mass index

BNC2 FTO NFAT5

6.40e-04411213EFO_0004340, EFO_0004616
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

BNC2 TRIP12 LRIG1 SPHKAP FTO NFAT5 HTT

7.78e-043641217EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseBipolar Disorder

PCLO TSNAX NDST3 NEFM PBRM1 KLK8 MBD5 NOS3

8.05e-044771218C0005586
DiseasePrimary Ciliary Dyskinesia

GAS8 DNAAF1 DNAH5

9.56e-04471213C4551720
Diseasekynurenic acid measurement

TRMT9B BUB3

1.26e-03131212EFO_0010506
Diseasechromosome-type aberration frequency

SUZ12 FTO

1.47e-03141212EFO_0009861
Diseasechronic lymphocytic leukemia

ZNF280D SFI1 SEPTIN2 FTO

1.49e-031191214EFO_0000095
DiseaseQT interval

PTGES2 FRAS1 ICE1 MBD5 CNOT1 PDZRN3 CAP2 XPO7

1.65e-035341218EFO_0004682
Diseasehypertension

COL6A3 HIC1 TAB2 PBRM1 RBM47 NOS3

1.71e-033071216EFO_0000537
Diseasepulse pressure measurement

TRAF7 SLAIN2 BNC2 COL6A3 HIC1 ZNF618 POGZ PBRM1 LRIG1 FTO MBD5 NFAT5 CNOT1 GOLGA4

1.72e-03139212114EFO_0005763
Diseasealcohol consumption measurement

WAPL ZNF280D ZNF618 PCLO ZNF521 NDST3 SPTBN5 SPHKAP FTO NFAT5 DNAH5 HTT XPO7

1.78e-03124212113EFO_0007878
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

ARHGAP29 ATM

1.93e-03161212C0334634
DiseaseBenign neoplasm of stomach

POLE ATM

2.18e-03171212C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE ATM

2.18e-03171212C0496905
DiseaseDystonia, Limb

COL6A3 CIZ1

2.18e-03171212C0751093
DiseaseDystonia, Diurnal

COL6A3 CIZ1

2.18e-03171212C0393610
DiseaseCarcinoma in situ of stomach

POLE ATM

2.18e-03171212C0154060
DiseaseDystonia, Paroxysmal

COL6A3 CIZ1

2.44e-03181212C0393588
Diseaseessential hypertension (is_implicated_in)

FTO NOS3

2.44e-03181212DOID:10825 (is_implicated_in)
Diseasedisease free survival

TRMT9B ICE1

2.44e-03181212EFO_0000409
Diseasecardiomyopathy (is_implicated_in)

TAB2 NOS3

2.72e-03191212DOID:0050700 (is_implicated_in)
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

NFKBIZ ATM

2.72e-03191212C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

NFKBIZ ATM

2.72e-03191212C2936783
DiseaseAlzheimer disease, polygenic risk score

FRAS1 NRF1 DNAJA2 GAS8 ZSWIM6 RNF38 NFAT5 MVK

2.92e-035861218EFO_0030082, MONDO_0004975
Diseasegrip strength measurement

PTGES2 ZNF280D TRIP12 JARID2 FTO NFAT5

3.27e-033501216EFO_0006941
Diseaseskin hydration measurement

FZD10 DTHD1

3.33e-03211212EFO_0009586
DiseaseStomach Carcinoma

POLE ATM

3.33e-03211212C0699791
Diseaseactivities of daily living score measurement

HNMT FZD10

3.33e-03211212EFO_0008451
DiseaseBronchiectasis

DNAAF1 DNAH5

3.65e-03221212C0006267
Diseasepsoriasis, type 2 diabetes mellitus

NFKBIZ FTO ANKRD52

3.66e-03751213EFO_0000676, MONDO_0005148
DiseaseParkinson's disease (is_implicated_in)

HNMT ATM HTT

3.80e-03761213DOID:14330 (is_implicated_in)
Diseaseclinical and behavioural ideal cardiovascular health

FTO NFAT5

3.99e-03231212EFO_0007654
DiseaseHuntington's disease (is_implicated_in)

NRF1 HTT

3.99e-03231212DOID:12858 (is_implicated_in)
DiseaseMental Depression

PCLO NEFM FTO NOS3 HTT

4.02e-032541215C0011570
Diseasetransient cerebral ischemia (biomarker_via_orthology)

NEFM FTO NOS3 HTT

4.05e-031571214DOID:224 (biomarker_via_orthology)
Diseasebody fat percentage

BNC2 TRIP12 LRIG1 SPHKAP FTO NFAT5 HTT

4.06e-034881217EFO_0007800

Protein segments in the cluster

PeptideGeneStartEntry
SFETDQVLLQHMKDH

ZNF280B

381

Q86YH2
SFETEHVLLQHMKDN

ZNF280D

396

Q6N043
AELVEMHFQNHQLAR

AARD

106

Q4LEZ3
QMIAVADENQNHHLE

SDF4

321

Q9BRK5
VVNDMSHDNHCHSQE

BNC2

666

Q6ZN30
LSQDENTLMDHQHSN

SPECC1L

326

Q69YQ0
HQMEENQHSTSEELQ

SPECC1L

401

Q69YQ0
DHQLKMHDLNTDQEN

BUB3

76

O43684
MHDLNTDQENLVGTH

BUB3

81

O43684
AEHLMLLEADNHVVN

DCAF6

751

Q58WW2
HHFTVNIRLNALDMD

ADCY10

976

Q96PN6
TEHMVAQVFRLQQAH

AMBRA1

971

Q9C0C7
MLLQHQAEVNATDHT

ANKRD52

876

Q8NB46
QVTDHLEYHLNVEMQ

CST11

76

Q9H112
HDAALLEMENNHTVA

MTUS2

1141

Q5JR59
QPHLFHNESSLVEQM

NDST3

386

O95803
DMLEEQHHQAMQFTA

PDZRN3

526

Q9UPQ7
VHFTSREDAVHAMNN

RBM47

286

A0AV96
DINDHTPTFLNNHML

PCDHB18P

71

Q96TA0
EMTHNHNFRLNEREV

SERPIND1

306

P05546
LIHNLFVSVMSHQDD

PBRM1

781

Q86U86
HMDIEQANLHQLATE

KIAA0100

1141

Q14667
DMDHNHLDNQIFTIM

FRAS1

1811

Q86XX4
HMLDIKEHNGQSAFQ

NFKBIZ

471

Q9BYH8
VLTNADMENFVHVHA

LRIG1

536

Q96JA1
AEDEFPDLSAHNNHM

CKB

16

P12277
KQHEDQSMIGHLQEE

GOLGA4

1786

Q13439
VVHDNLLNLDHDMVS

HIC1

76

Q14526
FMLDDLNATHQHCVL

FTO

296

Q9C0B1
AAHEKQHNIFLDQMT

KIF11

871

P52732
VETHAEMVHSAFQAQ

CAP2

71

P40123
FSHDQEQDPRALHME

KIF3C

726

O14782
RFLNHSTEHQCMQEF

HNMT

21

P50135
NMLSDSENSQHLELH

PCLO

4591

Q9Y6V0
GRQAENEHIHMDNLA

PLPPR5

276

Q32ZL2
DMQEITQHFAVCHVD

NDRG1

81

Q92597
RHVDNIMFENHTVAD

NPLOC4

221

Q8TAT6
HMATIEAHAVAQQVQ

NRF1

11

Q16656
PHLFHNQSVLAEQMA

NDST1

396

P52848
LQDFLLSQMSQHQVH

MED17

521

Q9NVC6
VNTILQSHHVNDMEG

POLE

1736

Q07864
MNTEAEQQLLHHARN

OSBPL1A

1

Q9BXW6
EAEIDMELFHQNHLI

NFAT5

491

O94916
HAATASFMKHLENEQ

NOS3

421

P29474
PAHLQTDFQMLHQDE

OTUD3

196

Q5T2D3
NLFHMQHLQAASLAD

ARHGAP29

431

Q52LW3
EHEVFQRDGNDLHMT

DNAJA2

256

O60884
MGHENQREAAIQLHE

FZD10

56

Q9ULW2
QFLADNHHQVRMLAA

ATM

1076

Q13315
QQMHIDSHEALGVLN

HTT

1621

P42858
QEHHLSEVQNMASEE

IDH3B

81

O43837
LTRLHMDHNNIEFIN

IGSF10

131

Q6WRI0
RENSNLHHQVEEMLQ

ICE1

66

Q9Y2F5
DFHVDLNHAAVRQML

DOCK10

441

Q96BY6
IEDRKTDFEMHHNIN

DOCK10

1961

Q96BY6
QEHLHFVMEISQDEI

DGKI

836

O75912
AHHYNNQIRTLMEED

COQ7

146

Q99807
HMFNLENFTSLHDIV

COL6A3

196

P12111
LALHAFHNTEVEAMQ

CTR9

291

Q6PD62
HMTVENINGNREETH

DTHD1

101

Q6ZMT9
FSQAMDLVQEFIQHH

LYST

426

Q99698
LNEAMAVLQHHDAVS

MAN2B1

436

O00754
NNHLEAAIHEAMSEL

MBD5

1451

Q9P267
QMAHNHLETVEDIQH

DNAAF1

201

Q8NEP3
SSDVEDHNHDLMLLQ

KLK8

111

O60259
EENMATHFSQLSLHN

HCFC1R1

61

Q9NWW0
KEQMDQISESNHLIH

EXOC1

246

Q9NV70
RAESLEHQVQSHLNM

nan

91

Q6ZN92
FTNFLLREVNDMHHT

FRY

666

Q5TBA9
NMTEDHVMHLLQNAD

CD74

136

P04233
AHQLAISDVHLSMEN

DRP2

296

Q13474
NEHDLQASEHVMDVV

DRP2

431

Q13474
RELLSHFNHQNMDAL

DNAH5

956

Q8TE73
LNDEMRFVTQIQHIH

JARID2

601

Q92833
QSVMVQLAFHVQDDH

FREM3

666

P0C091
VVMNGHVHDLQILDF

RASL10B

46

Q96S79
QNEMAERFHHVTVLQ

SFI1

306

A8K8P3
ELISSHAHEMENKQF

UTP20

741

O75691
DEVHHKNMIIDPNDN

SPHKAP

681

Q2M3C7
QSRMHEFHSQENLVV

STARD13

381

Q9Y3M8
NAVMVDIHDQLHQGT

RNF38

181

Q9H0F5
AQSLDDEDDNMHHAV

SLAIN2

321

Q9P270
MAQGSHQIDFQVLHD

TAB2

1

Q9NYJ8
KALEQQMESHREAHQ

KIF5C

701

O60282
FQKANMLDQHHTDLI

PTCHD1

101

Q96NR3
HFDSVMQLQEEAHLN

MOB1A

166

Q9H8S9
MQLQEEAHLNTSFKH

MOB1A

171

Q9H8S9
HIFAVANNAFQDMLH

MYH15

171

Q9Y2K3
VQEAHQQTLDDLHME

MYH15

1011

Q9Y2K3
NHMKHHVELDQQNGE

POGZ

511

Q7Z3K3
MHPNQEDHETFVDIN

SCARB2

356

Q14108
GLDAFDDLMQHTHIQ

PTGES2

346

Q9H7Z7
GLEHLHMDVAVNFSQ

OAF

136

Q86UD1
HQAFEAEVQAHEEVM

SPTBN5

2191

Q9NRC6
LQEQHQNLESEMSSH

SPTBN5

2931

Q9NRC6
QEENLSMEKSHHFED

CCDC110

121

Q8TBZ0
ASHFAVQECMAQHQD

COA4

36

Q9NYJ1
QEFQDHMSEPQHQQR

CIZ1

606

Q9ULV3
AIMNVLAELHQEHDL

CNOT1

1261

A5YKK6
NLLEHMQSHAADNEN

ZNF618

406

Q5T7W0
NDAQRHLHSNVMLEN

ZNF749

26

O43361
DVLQMQNSEHHGQSI

ZNF490

36

Q9ULM2
MNEFTVHILETVNAH

RPA4

151

Q13156
ELIDMNQHHLNALGV

MVK

296

Q03426
MEHVQADHELFLQAF

SUZ12

76

Q15022
QVHVANHMIDEGLNH

ZNF521

1211

Q96K83
LQQTDDRFHEMHVAL

TRAF7

291

Q6Q0C0
AMVFKTLDDSQHHQN

WAPL

701

Q7Z5K2
QEHMTEAQIHVFESQ

SCLT1

166

Q96NL6
AHLEQIFQEAHGMVA

SPTB

691

P11277
MHQDDLVNHTVDAVE

SUCO

706

Q9UBS9
VSEENHNHANERMLF

TNKS2

1016

Q9H2K2
AEHKEQFADMQDEHH

TRPM1

1496

Q7Z4N2
QFADMQDEHHVAEAI

TRPM1

1501

Q7Z4N2
FPNNEQLEQHMDVHL

ZBTB1

671

Q9Y2K1
ENDIQHLQDMSHFPD

WDR62

466

O43379
NEFTEHVDMQHPNVI

ZHX2

91

Q9Y6X8
QELSGEDMHQFHRAI

TSNAX

106

Q99598
MDFPQHSQHVLEQLN

ZBTB17

1

Q13105
MAHDGHIQFTQFIDN

ZSWIM6

1181

Q9HCJ5
HVDLHLEENSFQQGM

ZUP1

211

Q96AP4
SQEIDDHQHEMSVLQ

TRIP11

226

Q15643
QHEQMNATHTQLFLE

TRIP11

946

Q15643
LNQESDRFLHIMQQH

XPO7

961

Q9UIA9
MDHEAAQLEKQHVHN

TRMT9B

1

Q9P272
YNTLEEVLSHQEQHM

ZNF526

66

Q8TF50
ITHMQDLQEVTQDLH

SEPTIN2

281

Q15019
EQSHDMLVHVDNEAS

SNAPC5

56

O75971
MQESQETHISNHLDE

TTC23

1

Q5W5X9
FQQDTHSHENMLCEE

TEX15

691

Q9BXT5
VEDSNNHHLMLEASE

ZBED1

376

O96006
ITLLQMEHNFDIMNH

TRIP12

486

Q14669
MKNNFEHIQHIIIDD

SLFN5

636

Q08AF3
NDVQRHLHSDVMLEN

ZNF17

26

P17021
EKLQQAIAMHSQFHA

VPS37A

381

Q8NEZ2
NGQIHTLMQRHEEAF

GAS8

216

O95995
HNLQEEMHHLLEQFE

GOLGB1

336

Q14789
EMHHLLEQFEQAGQA

GOLGB1

341

Q14789
QLESHSDQNMHQAEE

NEFM

276

P07197