Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter binding	ANK1 ANK2 ANK3 ITPR1 ITPR2 PACS1 USP10 AKAP9 PACS2 LYN	4.78e-06	172	185	10	GO:0044325
GeneOntologyMolecularFunction	protein kinase activity	ANKK1 STK36 PDK1 NTRK2 CDK10 JAK1 STK10 PIK3C3 MAP4K5 TBK1 ROCK1 ATM STK40 MAPK8 LYN POMK EPHA8	4.53e-05	600	185	17	GO:0004672
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3 LYN	8.95e-05	10	185	3	GO:0140031
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA13 SMC1A RNF213 CHD9 ATP13A5 CHD4 HELQ MDN1 ACIN1 CHD6 CARNS1 DYNC1H1 VCP	2.49e-04	441	185	13	GO:0016887
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	2.55e-04	3	185	2	GO:0005220
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ANKK1 STK36 PDK1 NTRK2 CDK10 JAK1 STK10 PIK3C3 MAP4K5 TBK1 ROCK1 ATM STK40 MAPK8 LYN POMK EPHA8	3.33e-04	709	185	17	GO:0016773
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD9 CHD4 HLTF CHD6	3.71e-04	37	185	4	GO:0140658
GeneOntologyMolecularFunction	mediator complex binding	SMC1A NIPBL	5.06e-04	4	185	2	GO:0036033
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	STK36 ANK3 STAG1 SMC1A CNTRL NUMA1 CDC20B MEI1 HAUS2 DST AKAP9 ARHGEF10 TTC12 CFAP206 ROCK1 CFAP74 MAPK8 DYNC1H1 VCP DEUP1	7.21e-06	720	184	20	GO:0000226
GeneOntologyBiologicalProcess	organelle assembly	KNTC1 STK36 NRAP TBC1D30 STAG1 SYNE1 SMC1A CNTRL NUMA1 CDC20B RNF213 HAUS2 CDK10 USP10 MDN1 ARHGEF10 PIK3C3 TTC12 PACS2 CFAP206 CFAP74 ATM TRAPPC14 MAPK8 DYNC1H1 DEUP1	9.82e-06	1138	184	26	GO:0070925
GeneOntologyBiologicalProcess	establishment of mitotic sister chromatid cohesion	STAG1 SMC1A NIPBL	2.38e-05	7	184	3	GO:0034087
GeneOntologyCellularComponent	microtubule organizing center	CEP104 RAPGEF6 GPAA1 TBC1D30 CNTRL NUMA1 EVC CHD4 HAUS2 CDK10 AKAP9 ARHGEF10 CROCC2 TTC12 LRP1 NLRC5 CFAP206 ROCK1 ATM TRAPPC14 DYNC1H1 DEUP1	2.23e-05	919	185	22	GO:0005815
HumanPheno	Disinhibition	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	1.93e-05	807	72	26	HP:0000734
HumanPheno	Inappropriate behavior	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	1.93e-05	807	72	26	HP:0000719
HumanPheno	Abnormal response to social norms	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	1.93e-05	807	72	26	HP:5200123
HumanPheno	Social disinhibition	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	1.93e-05	807	72	26	HP:5200029
HumanPheno	Perseverative thought	ANK3 NTRK2 SMC1A KAT6A ZSWIM6 HUWE1 ITPR1 TRANK1 TBK1 PACS2 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP	5.17e-05	377	72	16	HP:0030223
HumanPheno	Abnormal social development	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 ITPR1 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	5.44e-05	908	72	27	HP:0025732
HumanPheno	Disordered formal thought process	ANK3 NTRK2 SMC1A KAT6A ZSWIM6 HUWE1 ITPR1 TRANK1 TBK1 PACS2 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP	6.89e-05	386	72	16	HP:0025769
HumanPheno	Abnormally increased volition	CEP104 PSAT1 ANK3 NRCAM NTRK2 SMC1A ZSWIM6 HUWE1 SHOC2 CDK10 PACS1 TRANK1 ANAPC1 ASL TBK1 PACS2 FTL ATM TRAPPC14 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP ZNF292	7.24e-05	869	72	26	HP:5200263
HumanPheno	Abnormal thought pattern	ANK3 NTRK2 SMC1A KAT6A ZSWIM6 HUWE1 ITPR1 TRANK1 TBK1 PACS2 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP	1.19e-04	404	72	16	HP:5200269
HumanPheno	Motor stereotypy	ANK3 NTRK2 SMC1A KAT6A ZSWIM6 HUWE1 ITPR1 TRANK1 PACS2 KCNT1 TRAPPC9 PUS7 VCP	1.20e-04	280	72	13	HP:0000733
HumanPheno	Restricted or repetitive behaviors or interests	ANK3 NTRK2 SMC1A KAT6A ZSWIM6 HUWE1 ITPR1 TRANK1 PACS2 NIPBL KCNT1 MED12 TRAPPC9 PUS7 VCP	1.47e-04	368	72	15	HP:0031432
Domain	ARM-type_fold	CEP104 STK36 STAG1 VEPH1 RICTOR HUWE1 MEI1 CWC22 ITPR1 ITPR2 ARFGEF3 THADA PIK3C3 TTC12 ATM NIPBL EIF3M GPRASP2	8.02e-09	339	185	18	IPR016024
Domain	Kinase-like_dom	ANKK1 STK36 NTRK2 CHD9 CDK10 JAK1 STK10 DST PIK3C3 MAP4K5 TBK1 ROCK1 ATM STK40 MAPK8 LYN POMK EPHA8	7.77e-06	542	185	18	IPR011009
Domain	TPR	RGPD2 RANBP2 CNOT10 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	4.38e-05	129	185	8	SM00028
Domain	TPR_repeat	RGPD2 RANBP2 CNOT10 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	5.44e-05	133	185	8	IPR019734
Domain	SAM_1	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	5.73e-05	68	185	6	PF00536
Domain	ZU5	ANK1 ANK2 ANK3	7.69e-05	9	185	3	SM00218
Domain	Phosphofurin_acidic_CS-1	PACS1 PACS2	9.76e-05	2	185	2	IPR019381
Domain	Pacs-1	PACS1 PACS2	9.76e-05	2	185	2	PF10254
Domain	ZU5	ANK1 ANK2 ANK3	1.09e-04	10	185	3	PS51145
Domain	Ank_3	ANK1 ANK3 ANKRD27	1.09e-04	10	185	3	PF13606
Domain	ZU5	ANK1 ANK2 ANK3	1.97e-04	12	185	3	PF00791
Domain	ZU5_dom	ANK1 ANK2 ANK3	1.97e-04	12	185	3	IPR000906
Domain	-	RGPD2 RANBP2 CNOT10 PSMD11 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	2.27e-04	207	185	9	1.25.40.10
Domain	SAM	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	2.41e-04	88	185	6	SM00454
Domain	SNF2_N	CHD9 CHD4 HLTF CHD6	2.70e-04	32	185	4	IPR000330
Domain	SNF2_N	CHD9 CHD4 HLTF CHD6	2.70e-04	32	185	4	PF00176
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	2.91e-04	3	185	2	IPR000493
Domain	LRR_1	NTRK2 CNTRL SHOC2 RSU1 LRRC31 PRELP NLRC5 LGR6 SLITRK6	3.44e-04	219	185	9	PF00560
Domain	SAM_DOMAIN	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	3.65e-04	95	185	6	PS50105
Domain	ARM-like	CEP104 STK36 STAG1 RICTOR HUWE1 MEI1 TTC12 NIPBL MED12 GPRASP2	3.72e-04	270	185	10	IPR011989
Domain	Prot_kinase_dom	ANKK1 STK36 NTRK2 CDK10 JAK1 STK10 MAP4K5 TBK1 ROCK1 STK40 MAPK8 LYN POMK EPHA8	3.80e-04	489	185	14	IPR000719
Domain	Leu-rich_rpt	NTRK2 CNTRL SHOC2 RSU1 LRRC31 PRELP NLRC5 LGR6 SLITRK6 NLRP8	3.83e-04	271	185	10	IPR001611
Domain	SAM	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	4.08e-04	97	185	6	IPR001660
Domain	PROTEIN_KINASE_DOM	ANKK1 STK36 NTRK2 CDK10 JAK1 STK10 MAP4K5 TBK1 ROCK1 STK40 MAPK8 LYN POMK EPHA8	4.13e-04	493	185	14	PS50011
Domain	TPR-like_helical_dom	RGPD2 RANBP2 CNOT10 PSMD11 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	5.39e-04	233	185	9	IPR011990
Domain	BK_channel_a	KCNU1 KCNT1	5.78e-04	4	185	2	PF03493
Domain	K_chnl_Ca-activ_BK_asu	KCNU1 KCNT1	5.78e-04	4	185	2	IPR003929
Domain	-	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	6.55e-04	106	185	6	1.10.150.50
Domain	PROTEIN_KINASE_ATP	ANKK1 STK36 NTRK2 CDK10 JAK1 STK10 MAP4K5 TBK1 ROCK1 STK40 MAPK8 LYN EPHA8	6.79e-04	459	185	13	PS00107
Domain	TPR-contain_dom	RGPD2 RANBP2 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	7.47e-04	150	185	7	IPR013026
Domain	SAM/pointed	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	1.10e-03	117	185	6	IPR013761
Domain	TPR_REGION	RGPD2 RANBP2 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	1.30e-03	165	185	7	PS50293
Domain	TPR	RGPD2 RANBP2 TRANK1 TMTC4 IFIT1B TTC12 LONRF3	1.30e-03	165	185	7	PS50005
Domain	-	NTRK2 CNTRL SHOC2 RSU1 LRRC31 PRELP NLRC5 LGR6 SLITRK6 NLRP8	1.40e-03	321	185	10	3.80.10.10
Domain	BRK	CHD9 CHD6	1.43e-03	6	185	2	SM00592
Domain	RIH_assoc-dom	ITPR1 ITPR2	1.43e-03	6	185	2	IPR013662
Domain	BRK_domain	CHD9 CHD6	1.43e-03	6	185	2	IPR006576
Domain	Ins145_P3_rec	ITPR1 ITPR2	1.43e-03	6	185	2	PF08709
Domain	RIH_assoc	ITPR1 ITPR2	1.43e-03	6	185	2	PF08454
Domain	RIH_dom	ITPR1 ITPR2	1.43e-03	6	185	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR2	1.43e-03	6	185	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR2	1.43e-03	6	185	2	IPR015925
Domain	-	ITPR1 ITPR2	1.43e-03	6	185	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR2	1.43e-03	6	185	2	PF01365
Domain	Liprin	PPFIA1 PPFIA3	1.43e-03	6	185	2	IPR029515
Domain	BRK	CHD9 CHD6	1.43e-03	6	185	2	PF07533
Domain	L_dom-like	NTRK2 CNTRL SHOC2 RSU1 LRRC31 PRELP NLRC5 LGR6 SLITRK6 NLRP8	1.64e-03	328	185	10	IPR032675
Domain	Chromo_domain	CHD9 CHD4 CHD6	1.66e-03	24	185	3	IPR023780
Domain	Pkinase_Tyr	ANKK1 NTRK2 JAK1 LYN POMK EPHA8	1.81e-03	129	185	6	PF07714
Pathway	KEGG_MEDICUS_REFERENCE_COHESIN_LOADING	STAG1 SMC1A NIPBL	7.07e-05	9	136	3	M47868
Pathway	KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2 LYN	7.07e-05	9	136	3	M47852
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	STAG1 SMC1A NIPBL	1.00e-04	10	136	3	M27178
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	STAG1 SMC1A NIPBL	1.00e-04	10	136	3	MM14892
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 RGPD2 RANBP2 STAG1 SMC1A NUMA1 HAUS2 AKAP9 DYNC1H1	1.49e-04	202	136	9	MM15362
Pathway	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS	RANBP2 NTRK2 POLR2B CNTRL RNF213 RICTOR PSMD11 SHOC2 AKAP9 MAPK8 LYN MAML3 GOLGA4 VCP	1.56e-04	464	136	14	M27547
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 RANBP2 STAG1 SMC1A CNTRL NUMA1 HAUS2 AKAP9 DYNC1H1	1.60e-04	204	136	9	M4217
Pathway	REACTOME_EICOSANOIDS	CYP4B1 PTGIS CYP4A22	1.81e-04	12	136	3	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4B1 PTGIS CYP4A22	1.81e-04	12	136	3	MM14845
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	ANK1 ANK2 ANK3 NRCAM	2.13e-04	31	136	4	M877
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	STAG1 SMC1A NIPBL	2.34e-04	13	136	3	MM15363
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	STAG1 SMC1A NIPBL	2.34e-04	13	136	3	M27661
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 RANBP2 ANK2 ANK3 NRCAM SYNE1 NTRK2 PPFIA1 NUMA1 ADGRB3 ARHGEF12 CHD4 HUWE1 PPFIA3 USP10 DST MDN1 AKAP9 ANAPC1 TBK1 CNKSR3 LRP1 MIOS ROCK1 QSER1 PCDH8 NIPBL KCNT1 DYNC1H1 GOLGA4	8.82e-15	963	187	30	28671696
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 PSAT1 ANK3 COPA PPFIA1 POLR2B RNF213 RICTOR PSMD11 HUWE1 BCAR1 PPFIA3 SHOC2 ITPR1 ITPR2 PACS1 TRIM11 MED4 AKAP9 TSR1 CASKIN2 MIOS PDP2 ROCK1 HSD17B3 MAPK8 GOLGA4	1.79e-11	1049	187	27	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PSAT1 ANK3 ABHD2 KAT6A EVC RNF213 CHD9 SRSF11 ZSWIM6 HUWE1 BCAR1 RSU1 C2CD2 PKNOX2 ARFGEF3 STK10 PACS1 USP10 THADA PIK3C3 TBK1 XPNPEP3 TTC12 LRP1 NLRC5 CHD6 QSER1 MAML3 EIF3M TRAPPC9 GOLGA4 SOS2	2.17e-11	1489	187	32	28611215
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	RANBP2 COPA SMC1A POLR2B NUMA1 RNF213 CHD9 CHD4 PPWD1 USP10 LIG3 TRIM11 MED4 MDN1 TSR1 ANAPC1 HLTF ACIN1 ATM QSER1 NIPBL EIF3M MED12 PUS7 VCP ZNF687	4.77e-11	1014	187	26	32416067
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ANK2 ANK3 NRCAM COPA STAG1 ENPP2 SYNE1 SMC1A ADGRB3 CHD9 CHD4 HUWE1 NR1D1 JAK1 MED4 MAN1A2 DST ARHGEF10 DROSHA MTIF2 LRP1 CHD6 ATM NIPBL GPRASP2 DYNC1H1 VCP ZNF292 SOS2	6.79e-11	1285	187	29	35914814
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FILIP1 RANBP2 RAPGEF6 COPA SMC1A NUMA1 RICTOR CHD4 HUWE1 NR1D1 STK10 PACS1 USP10 MDN1 ANAPC1 ACIN1 PACS2 ATM MAPK8 NIPBL GOLGA4 ZNF687	2.46e-10	774	187	22	15302935
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	KNTC1 RANBP2 PSAT1 COPA POLR2B NUMA1 RNF213 SRSF11 CHD4 PSMD11 HUWE1 ITPR1 ITPR2 ARFGEF3 USP10 LIG3 THADA DST MDN1 DIMT1 HLTF ATM TRAPPC14 EIF3M TRAPPC9 DYNC1H1 RBM34 VCP PTCD3	9.46e-10	1440	187	29	30833792
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RANBP2 COPA PDK1 SYNE1 SMC1A POLR2B CHD9 SRSF11 CHD4 CWC22 LIG3 DST TSR1 DROSHA XPNPEP3 MIOS ACIN1 CHD6 ATM NIPBL MED12 DYNC1H1 VCP ZNF292 PTCD3	9.93e-10	1082	187	25	38697112
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	RANBP2 COPA STAG1 SMC1A PPFIA1 SRSF11 CHD4 PSMD11 HUWE1 SHOC2 USP10 MDN1 ANAPC1 HLTF ACIN1 ATM NIPBL DYNC1H1	3.14e-09	582	187	18	20467437
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 RANBP2 PSAT1 COPA SYNE1 SMC1A POLR2B NUMA1 CHD4 PSMD11 HUWE1 CWC22 USP10 LIG3 THADA MDN1 DIMT1 TSR1 ANAPC1 TBK1 ACIN1 ATM NIPBL EIF3M DYNC1H1 GOLGA4 RBM34 PTCD3	3.27e-09	1425	187	28	30948266
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	KNTC1 RGPD2 RANBP2 PHF20 COPA STAG1 CNOT10 SYNE1 SMC1A NUMA1 SHOC2 HAUS2 CWC22 ITPR1 PACS1 ZNHIT6 TSR1 ANAPC1 NDUFAF7 ATM NIPBL EIF3M DYNC1H1 VCP PTCD3	3.70e-09	1155	187	25	20360068
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ANK1 COPA KAT6A NUMA1 CHD4 HUWE1 BCAR1 LARS2 JAK1 DST ARHGEF10 DYNC1H1 VCP	3.50e-08	332	187	13	37433992
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	RANBP2 COPA SMC1A NUMA1 RNF213 CHD4 HUWE1 MDN1 TSR1 ANAPC1 ACIN1 NIPBL DYNC1H1	3.50e-08	332	187	13	32786267
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RANBP2 ANK1 COPA SMC1A POLR2B NUMA1 SRSF11 CHD4 HUWE1 CWC22 ANKRD27 MDN1 DIMT1 TSR1 HLTF ACIN1 CRYBG1 CHD6 LYN NIPBL EIF3M DYNC1H1 RBM34 ZNF687 PTCD3	4.90e-08	1318	187	25	30463901
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD2 RANBP2 RAPGEF6 PPFIA1 CHD4 HUWE1 DST ANAPC1 TBK1 LRP1 CHD6 MED12 GPRASP2 ZNF687	7.16e-08	418	187	14	34709266
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 COPA SMC1A POLR2B NUMA1 RICTOR CHD4 PSMD11 HUWE1 ANKRD27 LIG3 DST MDN1 DIMT1 MAP4K5 HLTF ACIN1 NIPBL EIF3M MED12 DYNC1H1 GOLGA4 RBM34 VCP PTCD3	8.07e-08	1353	187	25	29467282
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ANK1 ANK3 PPFIA1 POLR2B NUMA1 CHD9 MEI1 TRANK1 MDN1 CROCC2 ATM MED12 RBM34 ZNF687 ZNF292	9.33e-08	497	187	15	36774506
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAPGEF6 RICTOR SRSF11 CWC22 ANKRD27 ITPR1 PACS1 LIG3 ZNHIT6 DST TSR1 CASKIN2 DROSHA MTIF2 TBK1 HLTF QSER1	9.88e-08	650	187	17	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	NRCAM ARHGEF12 CHD9 HUWE1 TRANK1 MDN1 ARHGEF10 DYNC1H1	9.97e-08	104	187	8	9205841
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 COPA NUMA1 CHD4 HUWE1 DST MDN1 TSR1 ANAPC1 ACIN1 ATM NIPBL MED12 DYNC1H1 RBM34 VCP PTCD3	1.05e-07	653	187	17	22586326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ANK2 ANK3 PDK1 SYNE1 PPFIA1 POLR2B RICTOR RSU1 ITPR1 ITPR2 USP10 THADA MED4 MDN1 AKAP9 ARHGEF10 TSR1 CASKIN2 MAP4K5 MTIF2 ATM GOLGA4 PUS7 RBM34 VCP PTCD3	1.27e-07	1487	187	26	33957083
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 TBC1D30 CNOT10 SYNE1 PPFIA1 POLR2B ARHGEF12 RICTOR USP10 MED4 MAN1A2 DST MDN1 DIMT1 TSR1 ANAPC1 DROSHA HLTF MIOS CRYBG1 CHD6 NIPBL EIF3M MED12 ZNF687 PTCD3	1.45e-07	1497	187	26	31527615
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK1 ANK2 ANK3	1.53e-07	3	187	3	33410423
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK1 ANK2 ANK3	1.53e-07	3	187	3	34289389
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KNTC1 RAPGEF6 CNOT10 SMC1A PPFIA1 RICTOR RSU1 USP10 DST AKAP9 ANAPC1 TBK1 TRAPPC14 TRAPPC9	1.58e-07	446	187	14	24255178
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	PPFIA1 POLR2B KAT6A RNF213 CHD9 RICTOR CHD4 PPFIA3 JAK1 THADA ZNHIT6 DIMT1 EML5 ANAPC1 DROSHA MTIF2 TBK1 LRP1 LONRF3 VCP ZNF687 PTCD3	1.74e-07	1116	187	22	31753913
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	COPA SMC1A POLR2B KAT6A NUMA1 CHD4 USP10 LIG3 MED4 MDN1 DIMT1 TSR1 PIK3C3 DROSHA MIOS ACIN1 MED12 RBM34	1.74e-07	759	187	18	35915203
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RANBP2 COPA SYNE1 SMC1A POLR2B NUMA1 SRSF11 CHD4 PSMD11 HUWE1 ITPR2 LIG3 DST MDN1 TBK1 XPNPEP3 ACIN1 LYN NIPBL DYNC1H1 VCP	1.77e-07	1024	187	21	24711643
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CNOT10 KAT6A PSMD11 JAK1 STK10 THADA ZNHIT6 MDN1 AKAP9 VILL CASKIN2 CROCC2 ROCK1 FGD6 EIF3M RBM34 VCP	2.24e-07	689	187	17	36543142
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RANBP2 PSAT1 COPA SMC1A POLR2B NUMA1 CHD9 SRSF11 CHD4 PSMD11 HUWE1 USP10 LIG3 MED4 DIMT1 AKAP9 TSR1 TBK1 ACIN1 LYN MED12 DYNC1H1 VCP	2.88e-07	1247	187	23	27684187
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	RANBP2 COPA STAG1 ADGRB3 ARHGEF12 SHOC2 ITPR1 USP10 MTIF2 MIOS CHD6 KCNT1 TRAPPC9 VCP	3.37e-07	475	187	14	31040226
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	CEP104 STK36 ABCA13 NUMA1 ARHGEF12 CWC22 STK10 TRIM11 DST MIOS DYNC1H1	4.53e-07	284	187	11	29459677
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KNTC1 STK36 TBC1D30 SMC1A RNF213 RICTOR TMEM200A THADA KAZN FGD6 MAML3 MED12 TRAPPC9 PUS7	5.26e-07	493	187	14	15368895
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	SMC1A CHD4 MDN1 ANAPC1 HLTF ROCK1 MAML3 TRAPPC9	5.26e-07	129	187	8	23022380
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ANK1 TBC1D30 RNF213 HUWE1 PPFIA3 ITPR2 LIG3 CCDC198 DST MDN1 DROSHA TBK1 CHD6 KAZN ATM LYN DYNC1H1	5.61e-07	736	187	17	29676528
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GPAA1 COPA PPFIA1 POLR2B NUMA1 SRSF11 PSMD11 LARS2 SHOC2 JAK1 USP10 DST TSR1 PIK3C3 TBK1 FTL MICA LYN NIPBL EIF3M DYNC1H1 RBM34 VCP	5.69e-07	1297	187	23	33545068
Pubmed	Functional proteomics mapping of a human signaling pathway.	ANK3 STAG1 PSMD11 HUWE1 ANKRD27 MED4 ZNHIT6 MAN1A2 DST DROSHA LRP1 ROCK1 FTL CHD6 DYNC1H1	8.38e-07	591	187	15	15231748
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	COPA SMC1A POLR2B NUMA1 RNF213 RICTOR CHD4 RSU1 JAK1 USP10 DIMT1 ARHGEF10 TSR1 TBK1 DYNC1H1	1.03e-06	601	187	15	33658012
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAPGEF6 PPFIA1 RICTOR SRSF11 BCAR1 ANKRD27 ARFGEF3 DST MDN1 AKAP9 ARHGEF10 CASKIN2 PIK3C3 CNKSR3 TRAPPC14 FGD6 TRAPPC9 GOLGA4	1.07e-06	861	187	18	36931259
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	CNOT10 NUMA1 CHD9 CHD4 CWC22 LIG3 MED4 MDN1 ANAPC1 NLRC5 ACIN1 NIPBL DYNC1H1 ZNF687	1.32e-06	533	187	14	30554943
Pubmed	Defining the membrane proteome of NK cells.	RANBP2 GPAA1 COPA CNOT10 CNTRL RNF213 CHD4 PSMD11 HUWE1 ANKRD27 ITPR1 ITPR2 BPNT2 MED4 MAN1A2 MDN1 PIK3C3 HLTF FTL MED12 DYNC1H1	1.48e-06	1168	187	21	19946888
Pubmed	BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.	ITPR1 ITPR2 LYN	1.52e-06	5	187	3	11782428
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	PPFIA1 RNF213 RICTOR ITPR1 ARFGEF3 MDN1 ATM	1.59e-06	104	187	7	31240132
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RANBP2 ANK2 ANK3 COPA SMC1A PPFIA1 NUMA1 ARHGEF12 RICTOR DST MAP4K5 ROCK1 MED12 DYNC1H1 GOLGA4 VCP	1.62e-06	708	187	16	39231216
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ABCA13 ENPP2 NTRK2 PPFIA1 RNF213 ZSWIM6 ITPR1 ARFGEF3 TRANK1 NLRC5 CRYBG1 POMK EIF3M GOLGA4	1.98e-06	552	187	14	10737800
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	RANBP2 PSAT1 SMC1A NUMA1 CHD4 HUWE1 PPFIA3 DST DROSHA ACIN1 DYNC1H1 VCP PTCD3	2.13e-06	477	187	13	31300519
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CNOT10 POLR2B HUWE1 HAUS2 LIG3 MED4 DST TSR1 TBK1 ROCK1 CHD6 EIF3M MED12 ZNF687 PTCD3	2.45e-06	645	187	15	25281560
Pubmed	In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.	STAG1 SMC1A NIPBL	3.02e-06	6	187	3	22628566
Pubmed	The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.	HUWE1 SHOC2 VCP	3.02e-06	6	187	3	34553755
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	RANBP2 NRAP ANK2 SYNE1 SMC1A CHD4 RSU1 DST AKAP9 DROSHA TBK1 LONRF3 VCP	3.33e-06	497	187	13	23414517
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	NUMA1 SRSF11 PACS1 LIG3 DST MAP4K5 ACIN1 NIPBL DYNC1H1 GOLGA4 PTCD3	4.50e-06	360	187	11	33111431
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	RANBP2 POLR2B NUMA1 RICTOR CHD4 HUWE1 ITPR1 ITPR2 USP10 ANAPC1 MIOS ZNF687	5.26e-06	440	187	12	34244565
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK1 ANK2 ANK3	5.27e-06	7	187	3	7495297
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	ANK2 COPA PPFIA1 POLR2B ARHGEF12 PSMD11 HUWE1 USP10 MED4 ZNHIT6 DIMT1 TSR1 ANAPC1 LRP1 EIF3M GPRASP2 RBM34 PTCD3	5.72e-06	971	187	18	33306668
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	STAG1 SMC1A KAT6A NUMA1 CHD9 CHD4 LIG3 TSR1 HLTF CHD6 QSER1 NIPBL RBM34 ZNF292	6.00e-06	608	187	14	36089195
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP104 ADGRB3 SHOC2 CWC22 ANKRD27 USP10 TRANK1 DST TSR1 CASKIN2 CARNS1 KCNT1 ZNF687	6.53e-06	529	187	13	14621295
Pubmed	TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.	PSMD11 JAK1 USP10 TRIM11	6.62e-06	23	187	4	29581427
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ANK3 PPFIA1 RICTOR JAK1 STK10 PACS1 DST CASKIN2 MAP4K5 ROCK1 LYN	6.96e-06	377	187	11	38117590
Pubmed	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	COPA ANAPC1 ACIN1 DYNC1H1	7.91e-06	24	187	4	33705438
Pubmed	A potential role for human cohesin in mitotic spindle aster assembly.	STAG1 SMC1A NUMA1	8.40e-06	8	187	3	11590136
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	OR5T3 PSAT1 ABHD2 RICTOR HPSE2 RSU1 ITPR1 PKNOX2 PIK3C3 ANAPC1 CARD9 VWA5A NIPBL TRAPPC9 DEUP1 NLRP8	9.43e-06	814	187	16	23251661
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CHD4 BCAR1 RSU1 CDK10 ITPR2 JAK1 STK10 CCDC198 DST AKAP9 ANAPC1 MAP4K5 TBK1 MAPK8 LYN EIF3M ZNF687	9.52e-06	910	187	17	36736316
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	ANK3 SMC1A PPFIA1 ARHGEF12 PSMD11 ARFGEF3 CASKIN2 PIK3C3 TBK1	9.56e-06	251	187	9	29778605
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	COPA PSMD11 ITPR2 AKAP9 MIOS FTL EIF3M	1.09e-05	139	187	7	25476789
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CEP104 KNTC1 RGPD2 RANBP2 ANK2 COPA STAG1 SYNE1 PPFIA1 CNTRL NUMA1 SRSF11 CHD4 DST MDN1 CNKSR3 ACIN1 CFAP74 CHD6 ATM NIPBL ZNF292	1.13e-05	1442	187	22	35575683
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	KNTC1 PPFIA1 POLR2B RNF213 HUWE1 ITPR2 ARHGEF10 ANAPC1 MIOS ROCK1 CHD6 QSER1 EIF3M GOLGA4 ZNF687	1.13e-05	733	187	15	34672954
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	RANBP2 POLR2B NUMA1 RNF213 CHD4 DIMT1 HLTF ACIN1	1.15e-05	195	187	8	19454010
Pubmed	Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.	RANBP2 CHD4 HUWE1 LIG3 BPNT2 ANAPC1 ACIN1	1.43e-05	145	187	7	28846114
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD2 RANBP2 SALL3 POLR2B CHD4 PSMD11 QSER1	1.50e-05	146	187	7	23892456
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	CNOT10 SHOC2 CWC22 DST ACIN1 QSER1 NIPBL MED12 RBM34 VCP PTCD3	1.52e-05	410	187	11	26949251
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	STK36 COPA SYNE1 SMC1A POLR2B CNTRL CHD4 PPFIA3 ITPR1 LIG3 HLTF CHD6 EIF3M DYNC1H1 ZNF687	1.57e-05	754	187	15	35906200
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	STAG1 SMC1A POLR2B RNF213 ITPR2 JAK1 LIG3 ACIN1 MED12 ZNF687	1.76e-05	341	187	10	32971831
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	RGPD2 RANBP2 ANK2 SMC1A NUMA1 SRSF11 CHD4 TSR1 ACIN1	1.76e-05	271	187	9	32433965
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK1 ANK2 ANK3	1.79e-05	10	187	3	22159418
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	ANKK1 RANBP2 STAG1 SMC1A MDN1 ANAPC1 NIPBL MED12 DYNC1H1	1.81e-05	272	187	9	31010829
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ANK2 SYNE1 DST AKAP9 GPRASP2 DYNC1H1 GOLGA4	1.87e-05	151	187	7	17043677
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	RAPGEF6 ANK3 PDK1 PPFIA1 RICTOR STK10 PACS1 DST ARHGEF10 MAP4K5 ROCK1	1.94e-05	421	187	11	36976175
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	RGPD2 RANBP2 CHD4 HUWE1 MDN1 TSR1 EIF3M	2.03e-05	153	187	7	26365490
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	TSR1 PDP2 CHD6 CARNS1 FGD6 KCNT1 ZNF687	2.03e-05	153	187	7	10718198
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	SALL3 NUMA1 CHD4 CWC22 ACIN1 ZNF687	2.07e-05	103	187	6	32744500
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	STK36 RAPGEF6 ANK3 NUMA1 BCAR1 PKNOX2 STK10 MAP4K5 ATM DYNC1H1 SOS2	2.36e-05	430	187	11	35044719
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	SMC1A CHD4 HUWE1 HELQ ACIN1 ATM NIPBL	2.40e-05	157	187	7	30686591
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RAPGEF6 SALL3 ANK3 ABHD2 PPFIA1 POLR2B CNTRL RICTOR HUWE1 ITPR1 PACS1 EML5 VILL TSR1 ACIN1 CRYBG1 ROCK1 QSER1	2.49e-05	1084	187	18	11544199
Pubmed	The protein interaction landscape of the human CMGC kinase group.	RANBP2 SMC1A POLR2B HUWE1 CDK10 MED4 AKAP9 DROSHA ACIN1 ROCK1 MAPK8 EIF3M MED12 RBM34	2.65e-05	695	187	14	23602568
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RANBP2 COPA SMC1A POLR2B NUMA1 CHD4 HUWE1 PPWD1 RSU1 USP10 DIMT1 TSR1 XPNPEP3 HLTF NIPBL EIF3M DYNC1H1 GOLGA4 PUS7 VCP PTCD3	2.71e-05	1415	187	21	28515276
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	CNOT10 POLR2B NUMA1 SRSF11 HUWE1 RSU1 USP10 MDN1 VCP	2.83e-05	288	187	9	23383273
Pubmed	CHD chromatin remodelling enzymes and the DNA damage response.	CHD4 CHD6	2.88e-05	2	187	2	23954449
Pubmed	A large Canadian cohort provides insights into the genetic architecture of human hair colour.	CDK10 EDNRB	2.88e-05	2	187	2	34737440
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	2.88e-05	2	187	2	15201137
Pubmed	Cholinergic augmentation of insulin release requires ankyrin-B.	ANK2 ITPR1	2.88e-05	2	187	2	20234002
Pubmed	Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.	ANK2 ITPR1	2.88e-05	2	187	2	14722080
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	2.88e-05	2	187	2	23582047
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	2.88e-05	2	187	2	26807827
Pubmed	NuMA1 promotes axon initial segment assembly through inhibition of endocytosis.	ANK3 NUMA1	2.88e-05	2	187	2	31727776
Pubmed	Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation.	ANK2 NRCAM	2.88e-05	2	187	2	11449000
Pubmed	Lyn tyrosine kinase promotes silencing of ATM-dependent checkpoint signaling during recovery from DNA double-strand breaks.	ATM LYN	2.88e-05	2	187	2	25173936
Pubmed	VCP/p97 controls signals of the ERK1/2 pathway transmitted via the Shoc2 scaffolding complex: novel insights into IBMPFD pathology.	SHOC2 VCP	2.88e-05	2	187	2	31091164
Pubmed	An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.	PACS1 PACS2	2.88e-05	2	187	2	22496420
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	2.88e-05	2	187	2	19120126
Pubmed	Phenotypes and genotypes in individuals with SMC1A variants.	SMC1A NIPBL	2.88e-05	2	187	2	28548707
Interaction	RAPGEF5 interactions	ANK1 ANK2 ANK3 ARHGEF12 RICTOR ARHGEF10 SOS2	1.21e-06	60	184	7	int:RAPGEF5
Interaction	EEF1AKMT3 interactions	KNTC1 CNOT10 SMC1A ARHGEF12 RICTOR HUWE1 NR1D1 ANKRD27 ZNHIT6 MDN1 ARHGEF10 ANAPC1 TBK1 MAPK8 GPAT2	1.34e-06	364	184	15	int:EEF1AKMT3
Interaction	BMI1 interactions	RANBP2 SYNE1 NUMA1 CHD4 CFAP141 PPWD1 ITPR2 ARFGEF3 DST AKAP9 CASKIN2 DROSHA NLRC5 ACIN1 ATM EIF3M MED12 DYNC1H1 ZNF687 PTCD3	2.72e-06	659	184	20	int:BMI1
Interaction	HERC2 interactions	CEP104 ANK2 COPA PPFIA1 ARHGEF12 SRSF11 PSMD11 ITPR2 MED4 DST AKAP9 LRRC31 TBK1 MIOS FTL C2CD6 EIF3M	3.89e-06	503	184	17	int:HERC2
Interaction	UBXN6 interactions	KNTC1 COPA ARHGEF12 RICTOR ZNHIT6 DST MDN1 ARHGEF10 ANAPC1 TXNRD3 MAPK8 GPAT2 VCP	9.58e-06	325	184	13	int:UBXN6
Interaction	OTUD7A interactions	ANK2 ANK3 ADGRB3 BCAR1 ARFGEF3 VCP	1.46e-05	58	184	6	int:OTUD7A
Interaction	DIRAS3 interactions	ANK3 PPFIA1 RICTOR HUWE1 DST PIK3C3 MAP4K5 MTIF2 LYN GOLGA4 VCP	3.03e-05	262	184	11	int:DIRAS3
Interaction	CDC5L interactions	STK36 RANBP2 COPA SYNE1 SMC1A PPFIA1 RICTOR CHD4 PSMD11 CFAP141 HUWE1 PPWD1 CWC22 USP10 DST MDN1 AKAP9 ANAPC1 HLTF NIPBL DYNC1H1	3.73e-05	855	184	21	int:CDC5L
Interaction	FBXO22 interactions	ANK1 ANK3 PPFIA1 POLR2B NUMA1 CHD9 BCAR1 MEI1 TRANK1 MDN1 CROCC2 ATM MED12 RBM34 ZNF687 ZNF292	3.79e-05	540	184	16	int:FBXO22
Interaction	USP15 interactions	ANK3 SMC1A KAT6A RNF213 CHD4 PSMD11 HUWE1 USP10 TRIM11 MED4 TSR1 ANAPC1 CARD9 TBK1 DYNC1H1 VCP	4.32e-05	546	184	16	int:USP15
Interaction	KCNA3 interactions	RANBP2 ANK2 ANK3 COPA ABCA13 NTRK2 SMC1A PPFIA1 NUMA1 ARHGEF12 RNF213 CHD9 RICTOR HELQ DST MAP4K5 ROCK1 MED12 DYNC1H1 GOLGA4 VCP	4.88e-05	871	184	21	int:KCNA3
Interaction	EED interactions	KNTC1 RANBP2 PSAT1 COPA STAG1 SMC1A POLR2B NUMA1 RICTOR CHD4 PSMD11 HUWE1 PPWD1 CWC22 USP10 LIG3 THADA MAN1A2 DIMT1 VILL DROSHA TBK1 ACIN1 FTL NIPBL EIF3M DYNC1H1 VCP ZNF687	4.98e-05	1445	184	29	int:EED
Interaction	TNIK interactions	ANK2 ANK3 SYNE1 BEX1 NTRK2 HUWE1 USP10 DST AKAP9 LYN PCDH8 DYNC1H1 GOLGA4	5.04e-05	381	184	13	int:TNIK
Interaction	MEX3A interactions	ANK1 COPA KAT6A NUMA1 CHD4 HUWE1 BCAR1 LARS2 JAK1 DST ARHGEF10 DYNC1H1 VCP	5.46e-05	384	184	13	int:MEX3A
Interaction	PCNT interactions	SYNE1 CNTRL CHD4 HUWE1 MED4 DST AKAP9 FTL NIPBL DEUP1	7.72e-05	241	184	10	int:PCNT
Interaction	BRD1 interactions	POLR2B KAT6A NUMA1 RICTOR CHD4 DIMT1 ANAPC1 MTIF2 TBK1 LRP1 QSER1 ZNF687	7.99e-05	344	184	12	int:BRD1
Interaction	SIGLECL1 interactions	KNTC1 STAG1 RNF213 CWC22 ARFGEF3 THADA TTC12	8.07e-05	113	184	7	int:SIGLECL1
Interaction	HMGN5 interactions	PSAT1 SMC1A POLR2B KAT6A NUMA1 PSMD11 LIG3 NIPBL	8.70e-05	154	184	8	int:HMGN5
Interaction	HECTD1 interactions	COPA SMC1A POLR2B KAT6A NUMA1 CHD4 HUWE1 USP10 LIG3 MED4 MDN1 DIMT1 ARHGEF10 LRRC31 TSR1 PIK3C3 DROSHA MIOS ACIN1 MED12 RBM34 VCP	9.69e-05	984	184	22	int:HECTD1
Interaction	SUMO2 interactions	RANBP2 COPA SMC1A NUMA1 RNF213 CHD4 HUWE1 DST MDN1 TSR1 ANAPC1 TBK1 ACIN1 NIPBL DYNC1H1 VCP	1.09e-04	591	184	16	int:SUMO2
Interaction	CCDC8 interactions	RANBP2 COPA NTRK2 SMC1A NUMA1 CHD4 HUWE1 ITPR2 LIG3 DST MDN1 TBK1 LYN NIPBL GPRASP2 DYNC1H1 VCP	1.13e-04	656	184	17	int:CCDC8
Interaction	H2AX interactions	RANBP2 BEX1 SMC1A NUMA1 CHD4 HUWE1 BCAR1 LIG3 MDN1 HLTF ATM MAPK8 NIPBL VCP ZNF687 PTCD3	1.14e-04	593	184	16	int:H2AX
Interaction	CTDP1 interactions	PPFIA1 POLR2B RNF213 RICTOR ITPR1 ARFGEF3 MED4 MDN1 ATM	1.24e-04	207	184	9	int:CTDP1
Interaction	NANOG interactions	RANBP2 SALL3 STAG1 POLR2B CHD4 PSMD11 HUWE1 MDN1 AKAP9 TSR1 HLTF QSER1 MED12 PTCD3	1.41e-04	481	184	14	int:NANOG
Interaction	BANK1 interactions	ITPR1 ITPR2 LYN	1.55e-04	12	184	3	int:BANK1
Interaction	CHL1 interactions	ANK1 ANK2 ANK3	1.55e-04	12	184	3	int:CHL1
Interaction	SIRT7 interactions	RANBP2 COPA NUMA1 CHD4 HUWE1 DST MDN1 TSR1 ANAPC1 ACIN1 FTL ATM NIPBL MED12 DYNC1H1 RBM34 VCP PTCD3	1.66e-04	744	184	18	int:SIRT7
Interaction	POLR1G interactions	SMC1A POLR2B KAT6A NUMA1 CHD9 HUWE1 LIG3 MED4 MDN1 TSR1 MTIF2 NIPBL RBM34 ZNF292	1.67e-04	489	184	14	int:POLR1G
Interaction	PINK1 interactions	RANBP2 PSAT1 SMC1A NUMA1 RICTOR CHD4 PSMD11 HUWE1 PPFIA3 DST DROSHA DHRS9 ACIN1 FTL DYNC1H1 VCP PTCD3	1.70e-04	679	184	17	int:PINK1
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD2 RANBP2 CNOT10 TRANK1 TMTC4 IFIT1B TTC12	1.43e-05	115	124	7	769
GeneFamily	Sterile alpha motif domain containing	PPFIA1 PPFIA3 CASKIN2 CNKSR3 KAZN EPHA8	3.16e-05	88	124	6	760
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	1.39e-04	3	124	2	297
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF12 ARHGEF10 FGD6 SOS2	1.09e-03	66	124	4	722
GeneFamily	Cohesin complex	STAG1 SMC1A	1.27e-03	8	124	2	1060
GeneFamily	Ankyrin repeat domain containing	ANKK1 ANK1 ANK2 ANK3 ANKRD27 TRANK1 CASKIN2	1.41e-03	242	124	7	403
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RANBP2 PHF20 STAG1 PPFIA1 POLR2B KAT6A CHD9 LARS2 SHOC2 C2CD2 ITPR1 TDRD7 STK10 DST MDN1 AKAP9 ARHGEF10 PIK3C3 MAP4K5 MTIF2 HLTF ROCK1 KAZN MAPK8 LYN NIPBL GOLGA4 ZNF292 SOS2	2.51e-12	856	185	29	M4500
Coexpression	HALLMARK_MITOTIC_SPINDLE	KNTC1 RAPGEF6 SMC1A CNTRL NUMA1 ARHGEF12 RICTOR BCAR1 DST ROCK1 FGD6 DYNC1H1	1.95e-08	199	185	12	M5893
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	RANBP2 RAPGEF6 PHF20 HTR7 SYNE1 POLR2B CNTRL KAT6A NUMA1 RNF213 RICTOR HUWE1 ITPR1 ITPR2 JAK1 STK10 PACS1 TRANK1 MAN1A2 AKAP9 VWA5A CD101 TBK1 NLRC5 CRYBG1 ROCK1 ATM NIPBL DYNC1H1 ZNF292	2.09e-07	1492	185	30	M40023
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	RAPGEF6 STAG1 PDK1 SYNE1 ARHGEF12 PPWD1 TMTC4 MTIF2 HLTF ATM	7.96e-07	184	185	10	M9005
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	STAG1 PPFIA1 KAT6A CHD9 LARS2 C2CD2 TDRD7 DST MDN1 AKAP9 PIK3C3 MAP4K5 LYN GOLGA4 ZNF292	1.23e-06	466	185	15	M13522
Coexpression	GSE22886_NAIVE_VS_MEMORY_TCELL_UP	NUMA1 HPSE2 HAUS2 AKAP9 TSR1 ANAPC1 CARD9 ATM ZNF292	1.04e-05	194	185	9	M4416
Coexpression	GSE11386_NAIVE_VS_MEMORY_BCELL_DN	KCTD19 SYNE1 CHD9 RICTOR MDN1 AKAP9 NLRC5 NIPBL	1.73e-05	158	185	8	M372
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN	PDK1 CNTRL SHOC2 JAK1 VWA5A NLRC5 TRAPPC14 NIPBL	2.47e-05	166	185	8	M8129
Coexpression	GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP	RAPGEF6 PSMD11 HUWE1 ZNHIT6 VWA5A MTIF2 EIF3M SOS2	3.46e-05	174	185	8	M6296
Coexpression	PILON_KLF1_TARGETS_UP	KNTC1 ANK3 EXD1 PPFIA1 HUWE1 BCAR1 SHOC2 ADAM12 C2CD2 EDNRB TBK1 MIOS LGR6	6.37e-05	503	185	13	M2226
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	KNTC1 RAPGEF6 ENPP2 PPFIA1 SRSF11 PPWD1 ITPR1 ITPR2 TDRD7 TBK1 HLTF ATM QSER1 NIPBL GOLGA4	6.97e-05	656	185	15	M18979
Coexpression	GSE3982_MAST_CELL_VS_BCELL_DN	CNTNAP3B PDK1 SYNE1 SMC1A HAUS2 JAK1 THADA CCDC198	8.30e-05	197	185	8	M5437
Coexpression	GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN	ANK1 KAT6A ARHGEF12 HUWE1 RSU1 JAK1 FTL NIPBL	8.90e-05	199	185	8	M5726
Coexpression	GSE27786_LSK_VS_CD4_TCELL_DN	NRAP RICTOR PKNOX2 JAK1 HLTF NLRC5 ROCK1 ZNF292	9.22e-05	200	185	8	M4747
Coexpression	GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP	CNOT10 JAK1 MED4 MAN1A2 TSR1 TXNRD3 FGD6 PTCD3	9.22e-05	200	185	8	M7172
Coexpression	GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP	PDK1 SRSF11 CFAP141 CDK10 USP10 EML5 MTIF2 XPNPEP3	9.22e-05	200	185	8	M4323
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	CHD9 RICTOR SRSF11 CHD4 SHOC2 BPNT2 ACIN1 ROCK1	1.13e-04	206	185	8	M2817
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	CHD9 RICTOR SRSF11 CHD4 SHOC2 BPNT2 ACIN1 ROCK1	1.21e-04	208	185	8	MM581
Coexpression	PILON_KLF1_TARGETS_UP	KNTC1 ANK3 EXD1 PPFIA1 HUWE1 BCAR1 SHOC2 ADAM12 C2CD2 EDNRB TBK1 MIOS LGR6	1.32e-04	541	185	13	MM1061
Coexpression	ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	COPA ENPP2 NTRK2 PSMD11 ARHGEF10 ATM MAPK8	1.46e-04	160	185	7	M11011
Coexpression	ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN	RAPGEF6 JAK1 STK10 NIPBL	1.47e-04	38	185	4	M1751
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	SALL3 NRCAM NTRK2 SMC1A ADGRB3 SRSF11 LARS2 CWC22 AKAP9 EML5 MTIF2 ROCK1 CFAP74 FGD6 NIPBL MAML3 GOLGA4	1.70e-06	498	184	17	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	PHF20 SMC1A POLR2B KAT6A ARHGEF12 CHD9 CHD4 LARS2 ZNHIT6 EML5 NDUFAF7 MTIF2 TBK1 CFAP74 MAML3 DYNC1H1 GOLGA4 ZNF292	4.54e-06	595	184	18	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	FILIP1 ANK2 ANK3 TBC1D30 NRCAM ABHD2 NTRK2 ADGRB3 HUWE1 ADAM12 HAUS2 EDNRB JAK1 LIG3 MAN1A2 AKAP9 ANAPC1 SLITRK6 MAPK8 VCP	2.99e-05	818	184	20	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	RAPGEF6 SMC1A POLR2B KAT6A CHD9 SRSF11 ITPR2 THADA ZNHIT6 MTIF2 TBK1 CFAP74 QSER1 FGD6 MAML3 ZNF292	3.43e-05	564	184	16	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	SMC1A POLR2B KAT6A ARHGEF12 CHD9 SRSF11 TMEM200A ZNHIT6 AKAP9 NDUFAF7 MTIF2 TBK1 QSER1 NIPBL MAML3 GPRASP2 ZNF292	3.56e-05	629	184	17	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1	RAPGEF6 PDK1 RICTOR ITPR2 JAK1 THADA MDN1 EML5 NLRC5 ATM MED12 ZNF292	3.89e-05	336	184	12	GSM538413_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	NTRK2 SMC1A AKAP9 EML5 MTIF2 ROCK1 FGD6 NIPBL GOLGA4	4.70e-05	192	184	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	PHF20 ANK2 NRCAM SMC1A CNTRL VEPH1 CHD9 SRSF11 CHD4 LARS2 PPWD1 PKNOX2 MDN1 DIMT1 AKAP9 EML5 MTIF2 ROCK1 CFAP74 ATM QSER1 TRAPPC14 MAPK8 NIPBL ZNF292	8.92e-05	1257	184	25	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	RANBP2 SALL3 ANK2 NRCAM NTRK2 ADGRB3 SRSF11 ZSWIM6 LARS2 CWC22 CDK10 EDNRB MDN1 AKAP9 EML5 ROCK1 CHD6 SLITRK6 TRAPPC14 GPRASP2 DEUP1	1.29e-04	983	184	21	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	PHF20 ANK2 NRCAM SMC1A CNTRL VEPH1 CHD9 SRSF11 CHD4 LARS2 PPWD1 CWC22 PKNOX2 MDN1 DIMT1 AKAP9 EML5 MTIF2 ROCK1 CFAP74 ATM QSER1 TRAPPC14 MAPK8 NIPBL DEUP1 ZNF292	1.51e-04	1459	184	27	facebase_RNAseq_e10.5_Emin_LatNas_2500
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 SYNE1 RNF213 RICTOR SRSF11 AKAP9 NLRC5 ATM GOLGA4 ZNF292	1.31e-08	199	187	10	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF213 SRSF11 AKAP9 ACIN1 ROCK1 ATM NIPBL DYNC1H1 GOLGA4 ZNF292	1.37e-08	200	187	10	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 RAPGEF6 SYNE1 KAT6A RNF213 AKAP9 NLRC5 CRYBG1 ATM	4.76e-08	171	187	9	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA ENPP2 NTRK2 SRSF11 DST EML5 GOLGA4 VCP	1.34e-07	193	187	9	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA ENPP2 NTRK2 SRSF11 DST EML5 GOLGA4 VCP	1.34e-07	193	187	9	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA ENPP2 SRSF11 HUWE1 DST EML5 GOLGA4 VCP	1.40e-07	194	187	9	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 PDK1 SYNE1 RNF213 SRSF11 AKAP9 ATM GOLGA4 ZNF292	1.60e-07	197	187	9	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	CEP104 ABHD2 CNTRL MAN1A2 AKAP9 MAP4K5 ROCK1 NIPBL GOLGA4	1.74e-07	199	187	9	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CEP104 CNTRL MAN1A2 AKAP9 MAP4K5 ROCK1 NIPBL GOLGA4 ZNF292	1.74e-07	199	187	9	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 SYNE1 ZSWIM6 EDNRB TMTC4 CARD9 PRELP LGR6	7.87e-07	175	187	8	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 SYNE1 ZSWIM6 EDNRB TMTC4 CARD9 PRELP LGR6	7.87e-07	175	187	8	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RANBP2 RAPGEF6 ANK3 RNF213 HUWE1 CRYBG1 ATM RBM34	1.01e-06	181	187	8	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COPA RICTOR PPWD1 ITPR2 DST AKAP9 ROCK1 ATM	1.30e-06	187	187	8	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 BEX1 ADAM12 GPR162 ITPR1 ARFGEF3 KCNT1 EPHA8	1.40e-06	189	187	8	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RGPD2 RANBP2 PHF20 RICTOR SRSF11 CRYBG1 GOLGA4 ZNF292	1.52e-06	191	187	8	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ENPP2 RICTOR ITPR2 AKAP9 CHD6 NIPBL GOLGA4 ZNF292	1.58e-06	192	187	8	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 PDK1 SYNE1 RNF213 SRSF11 AKAP9 ATM ZNF292	1.64e-06	193	187	8	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RAPGEF6 SYNE1 CNTNAP3 RNF213 AKAP9 NLRC5 GOLGA4	1.69e-06	135	187	7	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAT6A CHD9 JAK1 MAN1A2 DST LRP1 LONRF3 MAML3	1.77e-06	195	187	8	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 PDK1 SYNE1 RNF213 NLRC5 PDP2 ATM ZNF292	1.91e-06	197	187	8	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ABHD2 SYNE1 ARHGEF12 RNF213 JAK1 STK10 ATM LGR6	1.99e-06	198	187	8	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA POLR2B ARHGEF12 HUWE1 SHOC2 DST MAP4K5 VCP	1.99e-06	198	187	8	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRCAM ADGRB3 ADAM12 TMEM200A PKNOX2 DST PRELP LRP1	1.99e-06	198	187	8	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	ANK2 NRCAM ADGRB3 ADAM12 PKNOX2 DST PRELP KAZN	1.99e-06	198	187	8	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ABHD2 SYNE1 ARHGEF12 RNF213 JAK1 STK10 ATM LGR6	1.99e-06	198	187	8	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA POLR2B ARHGEF12 HUWE1 SHOC2 DST MAP4K5 VCP	1.99e-06	198	187	8	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	ANK2 BEX1 CHD9 SRSF11 ZSWIM6 AKAP9 MAPK8 ZNF292	1.99e-06	198	187	8	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 STAG1 ADGRB3 ZSWIM6 ITPR2 PACS1 MAML3 TRAPPC9	2.06e-06	199	187	8	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	MAN1A2 DST AKAP9 MAP4K5 ROCK1 NIPBL GOLGA4 ZNF292	2.06e-06	199	187	8	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KAT6A ARHGEF12 RNF213 EDNRB DST ARHGEF10 CASKIN2 DYNC1H1	2.14e-06	200	187	8	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RANBP2 RAPGEF6 ANK3 RNF213 RICTOR CRYBG1 ATM	4.42e-06	156	187	7	1545169694f686d28648a68b552c2ae606599d66
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 BEX1 AKAP9 DYNC1H1 RBM34	4.91e-06	59	187	5	74590437b1d9a2a8fe56d79b2e66803528b81298
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RANBP2 RAPGEF6 ANK3 KAT6A ITPR1 CRYBG1 ATM	5.67e-06	162	187	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 HTR7 ABHD2 ADAM12 SYCE1L KAZN LGR6	6.92e-06	167	187	7	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	8.72e-06	173	187	7	61907116a1460bc157ba73b5edd108db7dd5de4b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 EPHA8	9.39e-06	175	187	7	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	9.75e-06	176	187	7	4843af68f013732c28a8b8edad30d5fa0f2b084b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	9.75e-06	176	187	7	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 CYP4B1 ENPP2 ASL PDP2 FTL GPAT2	1.01e-05	177	187	7	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 CYP4B1 ENPP2 ASL PDP2 FTL GPAT2	1.01e-05	177	187	7	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SYNE1 NUMA1 RICTOR DST MDN1 CASKIN2 DYNC1H1	1.01e-05	177	187	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RANBP2 STAG1 SYNE1 SMC1A CNTRL AKAP9	1.05e-05	178	187	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	1.09e-05	179	187	7	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	1.17e-05	181	187	7	7704f236831cffe4f2a75d4c461eb88b4177e206
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 KAT6A RNF213 AKAP9 NLRC5 ATM	1.23e-05	121	187	6	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	RNF213 CHD9 TRANK1 DST NLRC5 FGD6 ZNF292	1.26e-05	183	187	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAPGEF6 NRCAM RICTOR NLRC5 CFAP74 ATM	1.35e-05	123	187	6	511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	KNTC1 RNF213 HUWE1 TMEM200A ITPR2 PDP2 ZNF292	1.40e-05	186	187	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 RNF213 RICTOR HUWE1 ITPR1 NIPBL DYNC1H1	1.50e-05	188	187	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FILIP1 ANK3 NRCAM HTR7 HPSE2 PPWD1 TDRD7	1.50e-05	188	187	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FILIP1 ANK3 NRCAM HTR7 HPSE2 PPWD1 TDRD7	1.50e-05	188	187	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FILIP1 ANK3 NRCAM HTR7 HPSE2 PPWD1 TDRD7	1.50e-05	188	187	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAN1A2 AKAP9 CRYBG1 CHD6 ATM GOLGA4 ZNF292	1.55e-05	189	187	7	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FILIP1 NRAP ANK2 ANK3 ABHD2 ARHGEF12 CNKSR3	1.55e-05	189	187	7	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FILIP1 NRAP ANK2 ANK3 ABHD2 ARHGEF12 CNKSR3	1.60e-05	190	187	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KAT6A ARHGEF12 CHD4 JAK1 DST AKAP9 GOLGA4	1.60e-05	190	187	7	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 PTGIS ITPR1 PKNOX2 DST EML5 LRP1	1.66e-05	191	187	7	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 PTGIS EDNRB ITPR1 PKNOX2 DST LRP1	1.66e-05	191	187	7	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 ENPP2 ABHD2 NTRK2 ADAM12 DST SLITRK6	1.66e-05	191	187	7	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 PTGIS ITPR1 PKNOX2 DST EML5 LRP1	1.66e-05	191	187	7	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 ENPP2 ABHD2 NTRK2 ADAM12 DST SLITRK6	1.71e-05	192	187	7	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 RAPGEF6 ANK3 RNF213 SRSF11 CRYBG1 ATM	1.71e-05	192	187	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CHD9 CHD4 SHOC2 ITPR1 ARHGEF10 LYN VCP	1.77e-05	193	187	7	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RANBP2 SMC1A HUWE1 ARFGEF3 AKAP9 POMK DYNC1H1	1.77e-05	193	187	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 KAT6A ARHGEF12 EDNRB ARHGEF10 CASKIN2 NLRC5	1.77e-05	193	187	7	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	RICTOR ITPR2 AKAP9 CHD6 NIPBL GOLGA4 ZNF292	1.77e-05	193	187	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA ENPP2 SRSF11 DST EML5 GOLGA4 VCP	1.83e-05	194	187	7	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	ADGRB3 ADAM12 PTGIS PKNOX2 PRELP LRP1 KAZN	1.83e-05	194	187	7	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	FILIP1 NRAP ANK2 ANK3 ABHD2 NTRK2 CNKSR3	1.83e-05	194	187	7	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	STAG1 ADGRB3 CHD9 PTGIS PRELP LRP1 KAZN	1.83e-05	194	187	7	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 CHD4 HUWE1 DST AKAP9 DYNC1H1 GOLGA4	1.89e-05	195	187	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 CHD4 HUWE1 DST AKAP9 DYNC1H1 GOLGA4	1.89e-05	195	187	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAG1 ENPP2 SMC1A CHD9 AKAP9 PRELP LRP1	1.89e-05	195	187	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ANK3 ABCA13 CYP4B1 SYNE1 ARHGEF12 ARFGEF3 CNKSR3	1.96e-05	196	187	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ANK3 ABCA13 CYP4B1 SYNE1 ARHGEF12 ARFGEF3 CNKSR3	1.96e-05	196	187	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 ANK3 NRCAM VEPH1 EVC CCDC198 KAZN	1.96e-05	196	187	7	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 RNF213 STK10 TRANK1 NLRC5 ATM LGR6	2.02e-05	197	187	7	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANK3 ENPP2 ARFGEF3 DST TMTC4 PACS2 CARNS1	2.02e-05	197	187	7	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	FILIP1 CYP3A5 CYP4B1 MEI1 ITPR1 DST PRELP	2.02e-05	197	187	7	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 SYNE1 ADAM12 EDNRB MDN1 MAP4K5 KAZN	2.09e-05	198	187	7	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CNTRL MAN1A2 AKAP9 MAP4K5 ROCK1 NIPBL GOLGA4	2.09e-05	198	187	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 RNF213 JAK1 STK10 TRANK1 ATM LGR6	2.16e-05	199	187	7	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	ARHGEF12 MAN1A2 AKAP9 CRYBG1 ROCK1 NIPBL GOLGA4	2.16e-05	199	187	7	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	MAN1A2 AKAP9 MAP4K5 ROCK1 NIPBL GOLGA4 ZNF292	2.16e-05	199	187	7	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 RNF213 JAK1 STK10 TRANK1 ATM LGR6	2.16e-05	199	187	7	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	CNTNAP3B ANK2 ANK3 ARHGEF12 ARFGEF3 DST AKAP9	2.16e-05	199	187	7	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	MAN1A2 AKAP9 MAP4K5 ROCK1 EIF3M GOLGA4 ZNF292	2.16e-05	199	187	7	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	CNTNAP3B ANK2 ANK3 ARHGEF12 ARFGEF3 DST AKAP9	2.16e-05	199	187	7	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FILIP1 CYP3A5 ENPP2 DST AKAP9 PRELP FTL	2.16e-05	199	187	7	212e89d097753790061310373a1fafba773488b6
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSAT1 BEX1 VEPH1 ADGRB3 EDNRB DST WNT16	2.16e-05	199	187	7	a816b0eed80530113b7e720bbd2311a544ed8ed1
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FILIP1 CYP3A5 ENPP2 DST AKAP9 PRELP FTL	2.16e-05	199	187	7	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	MAN1A2 AKAP9 ROCK1 NIPBL EIF3M GOLGA4 ZNF292	2.16e-05	199	187	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KAT6A ARHGEF12 RNF213 EDNRB DST CASKIN2 DYNC1H1	2.23e-05	200	187	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ENPP2 BEX1 ARHGEF12 RNF213 DST FGD6 NIPBL	2.23e-05	200	187	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 CNTNAP3 HPSE2 ADAM12 WNT16 PCDH8	2.23e-05	200	187	7	2441a36d363b799a4692aa697f969cda056c2d60
ToppCell	mLN-Mast_cell-Mast\|mLN / Region, Cell class and subclass	ENPP2 BEX1 ARHGEF12 ADAM12 EDNRB VWA5A DHRS9	2.23e-05	200	187	7	81ea6e7a3940277751faf9097b30198159998c7b
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KAT6A ARHGEF12 RNF213 EDNRB DST CASKIN2 DYNC1H1	2.23e-05	200	187	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	mLN-Mast_cell\|mLN / Region, Cell class and subclass	ENPP2 BEX1 ARHGEF12 ADAM12 EDNRB VWA5A DHRS9	2.23e-05	200	187	7	9a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCell	mLN-(7)_Mast_cell-(70)_Mast\|mLN / shred on region, Cell_type, and subtype	ENPP2 BEX1 ARHGEF12 ADAM12 EDNRB VWA5A DHRS9	2.23e-05	200	187	7	a6c258cae678be581b1d85cf3446c65c34b13499
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RNF213 CHD4 JAK1 ROCK1 NIPBL DYNC1H1 GOLGA4	2.23e-05	200	187	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 AKAP9 ROCK1 ATM DYNC1H1 GOLGA4 ZNF292	3.73e-07	49	103	7	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 ARHGEF12 RNF213 DST DYNC1H1	1.10e-04	50	103	5	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drug	Thimerosal	PHF20 ANK2 STAG1 PDK1 SMC1A KAT6A CDC20B ARHGEF12 CHD9 CHD4 SHOC2 C2CD2 EDNRB TDRD7 ARFGEF3 USP10 DST AKAP9 EML5 ARHGEF10 MAP4K5 MICA ATM LGR6 MAPK8 FGD6 NIPBL VCP	5.17e-07	1199	186	28	ctd:D013849
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; PC3; HT_HG-U133A	ANK3 ADAM12 PACS1 BPNT2 AKAP9 NDUFAF7 ACIN1 LONRF3 TRAPPC14 LYN ZNF292	5.46e-07	192	186	11	7280_DN
Drug	THIP Hydrochloride; Down 200; 22.6uM; PC3; HT_HG-U133A	PDK1 ARHGEF12 PPFIA3 ITPR1 BPNT2 XPNPEP3 CRYBG1 KAZN TRAPPC14 LYN EIF3M	7.41e-07	198	186	11	7266_DN
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	ANK2 TBC1D30 PDK1 NUMA1 MDN1 TSR1 DHRS9 KAZN EIF3M PUS7	3.53e-06	188	186	10	6186_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	ANK3 COPA BEX1 NTRK2 NUMA1 ARHGEF12 SRSF11 CHD4 PACS1 CD101	4.46e-06	193	186	10	4321_DN
Drug	Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A	CEP104 PHF20 NTRK2 SMC1A CNTRL MAN1A2 XPNPEP3 ATM MAPK8 EIF3M	4.46e-06	193	186	10	4118_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; HL60; HT_HG-U133A	CEP104 PHF20 NRCAM COPA NR1D1 CDK10 PRELP QSER1 TRAPPC14 MAPK8	5.11e-06	196	186	10	2942_DN
Drug	Thiorphan [76721-89-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A	NTRK2 KAT6A NR1D1 ITPR1 PACS1 MAN1A2 CD101 WNT16 MIOS MAPK8	5.35e-06	197	186	10	2752_UP
Drug	Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A	STAG1 SYNE1 SMC1A ARHGEF12 ADAM12 CDK10 ITPR2 DIMT1 MAP4K5 MAPK8	5.59e-06	198	186	10	4584_DN
Drug	Fenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A	NRCAM CYP3A5 HUWE1 ITPR2 TRANK1 MAN1A2 CCDC198 LRRC31 CARD9 WNT16	5.85e-06	199	186	10	3805_UP
Drug	Clorgyline	CHD9 RICTOR SHOC2 DST AKAP9 SLITRK6 NIPBL GOLGA4 ZNF292	1.03e-05	168	186	9	ctd:D003010
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	KNTC1 PHF20 TBC1D30 STAG1 PPFIA1 CHD9 MDN1 PIK3C3 NIPBL	2.05e-05	183	186	9	7498_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	TBC1D30 CHD9 C2CD2 ZNHIT6 TBK1 MIOS NIPBL ZNF292 SOS2	2.14e-05	184	186	9	2321_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	CEP104 TBC1D30 KAT6A C2CD2 MDN1 CARD9 XPNPEP3 TRAPPC9 PUS7	2.64e-05	189	186	9	1171_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	BEX1 SMC1A KAT6A NUMA1 CHD4 HAUS2 XPNPEP3 ATM SOS2	2.87e-05	191	186	9	4283_DN
Drug	Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ABHD2 LIG3 CASKIN2 XPNPEP3 TRAPPC14 LYN FGD6 EIF3M ZNF292	3.38e-05	195	186	9	7426_DN
Drug	Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A	CEP104 NUMA1 ITPR1 ITPR2 ARHGEF10 VWA5A NDUFAF7 ATM SOS2	3.38e-05	195	186	9	4799_UP
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A	ANK3 NRCAM CNTRL ADGRB3 VWA5A LRP1 MIOS TRAPPC9 SOS2	3.52e-05	196	186	9	3817_UP
Drug	Strophanthidin [66-28-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	CEP104 PPFIA3 NR1D1 PACS1 LIG3 PACS2 TRAPPC9 RBM34 SOS2	3.52e-05	196	186	9	7182_UP
Drug	PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A	TBC1D30 COPA CYP3A5 KAT6A ITPR2 PKNOX2 PRELP DHRS9 SOS2	3.52e-05	196	186	9	4291_UP
Drug	amitriptyline hydrochloride; Down 200; 1uM; MCF7; HG-U133A	STAG1 CDK10 LIG3 BPNT2 VWA5A XPNPEP3 HSD17B3 TRAPPC14 NIPBL	3.52e-05	196	186	9	167_DN
Drug	Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A	ARHGEF12 PPFIA3 ANKRD27 ITPR1 LIG3 ACIN1 ATM LONRF3 NIPBL	3.52e-05	196	186	9	2119_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A	STAG1 SRSF11 ITPR1 LIG3 THADA DIMT1 TSR1 CARD9 PUS7	3.52e-05	196	186	9	2035_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A	PHF20 ANK3 NRCAM SMC1A KAT6A ADAM12 VWA5A WNT16 SOS2	3.81e-05	198	186	9	4464_DN
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A	STAG1 EVC ADAM12 ITPR1 NDUFAF7 TBK1 PACS2 NIPBL MED12	3.81e-05	198	186	9	6332_DN
Drug	3-doxylandrostanol	ANK1 ANK2 ANK3	4.35e-05	9	186	3	CID000189075
Drug	1pzj	SYNE1 LARS2 JAK1 DROSHA DHRS9 MAPK8 DYNC1H1 GOLGA4	7.15e-05	167	186	8	CID000447976
Drug	26-nor-25-doxylcholestanol	ANK1 ANK2 ANK3	8.44e-05	11	186	3	CID000125890
Drug	AC1NSPXR	ANK1 ANK2 ANK3	8.44e-05	11	186	3	CID005313815
Drug	delta 8-THC	CYP3A5 DST TBK1	8.44e-05	11	186	3	CID000002977
Drug	dimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A	PDK1 ADAM12 ITPR1 PRELP LRP1 TRAPPC14 MAPK8 ZNF292	8.79e-05	172	186	8	584_UP
Drug	xestospongin C	ENPP2 ITPR1 ITPR2	1.12e-04	12	186	3	ctd:C511704
Drug	PD-V	STAG1 SYNE1 ASL	1.12e-04	12	186	3	CID000444615
Drug	geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A	SYNE1 HUWE1 PTGIS VWA5A DHRS9 MAPK8 TRAPPC9 RBM34	1.16e-04	179	186	8	4452_UP
Drug	Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; HL60; HT_HG-U133A	ANK2 TBC1D30 LIG3 MDN1 DIMT1 TSR1 DHRS9 PUS7	1.25e-04	181	186	8	2136_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	TBC1D30 CHD9 PPWD1 ZNHIT6 AKAP9 TBK1 NIPBL SOS2	1.30e-04	182	186	8	3887_DN
Drug	mancozeb	SYNE1 TRIM11 VCP	1.44e-04	13	186	3	CID003034368
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; HL60; HT_HG-U133A	TBC1D30 KAT6A NUMA1 TRANK1 ARHGEF10 KAZN TRAPPC14 ZNF292	1.51e-04	186	186	8	2426_DN
Drug	Clioquinol	NUMA1 AKAP9 DROSHA ATM MAPK8	1.53e-04	62	186	5	ctd:D007464
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	ANK3 COPA KAT6A NUMA1 SRSF11 CHD4 VWA5A SOS2	1.75e-04	190	186	8	4322_DN
Drug	Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; HL60; HT_HG-U133A	ANK2 COPA SMC1A DIMT1 DHRS9 LONRF3 NIPBL SOS2	1.88e-04	192	186	8	1266_DN
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; PC3; HT_HG-U133A	TBC1D30 COPA ARHGEF12 ADAM12 VWA5A XPNPEP3 FGD6 SOS2	1.88e-04	192	186	8	6659_DN
Drug	Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A	ANK1 NTRK2 CNTRL NR1D1 ADAM12 ITPR1 MAN1A2 CARD9	1.88e-04	192	186	8	5620_UP
Drug	Antimycin A [1397-94-0]; Down 200; 7.2uM; PC3; HT_HG-U133A	TBC1D30 ARHGEF12 EVC SRSF11 ADAM12 LIG3 NIPBL TRAPPC9	1.95e-04	193	186	8	2098_DN
Drug	Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ANK1 SYNE1 KAT6A ARHGEF12 PPFIA3 ITPR1 PKNOX2 LONRF3	1.95e-04	193	186	8	2764_UP
Drug	Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; PC3; HT_HG-U133A	BEX1 NTRK2 HUWE1 ITPR2 PKNOX2 WNT16 XPNPEP3 DHRS9	1.95e-04	193	186	8	6678_UP
Drug	Podophyllotoxin [518-28-5]; Down 200; 9.6uM; HL60; HT_HG-U133A	TBC1D30 LIG3 DIMT1 TSR1 CARD9 KAZN EIF3M PUS7	1.95e-04	193	186	8	2540_DN
Drug	iminophosphamide	CYP3A5 SYNE1	1.98e-04	3	186	2	CID000134773
Drug	PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A	SMC1A CNTRL ARHGEF12 ITPR2 ROCK1 ATM NIPBL EIF3M	2.02e-04	194	186	8	7086_UP
Drug	Indomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A	CEP104 ANK3 COPA SYNE1 SMC1A CNTRL ARHGEF12 SOS2	2.02e-04	194	186	8	5049_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A	NTRK2 KAT6A NUMA1 SRSF11 CHD4 DIMT1 VWA5A CD101	2.02e-04	194	186	8	4319_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A	PHF20 CYP3A5 SYNE1 NUMA1 WNT16 MIOS ATM LONRF3	2.02e-04	194	186	8	2893_UP
Drug	Felodipine [72509-76-3]; Down 200; 10.4uM; HL60; HT_HG-U133A	TBC1D30 ENPP2 NUMA1 NR1D1 VWA5A XPNPEP3 PACS2 ATM	2.02e-04	194	186	8	2433_DN
Drug	Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A	PHF20 SMC1A NUMA1 MAN1A2 ARHGEF10 XPNPEP3 ATM MAPK8	2.02e-04	194	186	8	4141_DN
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	NR1D1 ADAM12 LIG3 VWA5A DHRS9 TTC12 RBM34 SOS2	2.02e-04	194	186	8	3779_DN
Drug	Reserpine [50-55-5]; Up 200; 6.6uM; PC3; HT_HG-U133A	ENPP2 ARHGEF12 CDK10 VWA5A WNT16 LRP1 MAPK8 SOS2	2.09e-04	195	186	8	4203_UP
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A	PHF20 COPA SMC1A PPFIA3 ITPR1 VWA5A QSER1 RBM34	2.09e-04	195	186	8	4980_DN
Drug	Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	SMC1A CDK10 PACS1 THADA CASKIN2 TRAPPC14 LYN MED12	2.09e-04	195	186	8	3519_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A	CEP104 ABHD2 SMC1A SRSF11 ADAM12 PPWD1 CDK10 ITPR1	2.09e-04	195	186	8	3710_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	NRCAM CNTRL NUMA1 CDK10 AKAP9 TSR1 MAP4K5 LYN	2.09e-04	195	186	8	1665_DN
Drug	SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A	COPA ABHD2 NUMA1 PTGIS ITPR1 MAP4K5 NDUFAF7 SOS2	2.09e-04	195	186	8	7054_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	ANK3 NTRK2 CNTRL ITPR1 CASKIN2 VWA5A MAP4K5 LYN	2.09e-04	195	186	8	2311_DN
Drug	Epiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A	PHF20 ENPP2 NR1D1 BPNT2 WNT16 KAZN TRAPPC14 SOS2	2.09e-04	195	186	8	2444_DN
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; MCF7; HT_HG-U133A	PDK1 PSMD11 ITPR2 CCDC198 MAP4K5 ATM MAPK8 SOS2	2.09e-04	195	186	8	3237_DN
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A	PHF20 ABHD2 NUMA1 NR1D1 NDUFAF7 ATM TRAPPC14 SOS2	2.09e-04	195	186	8	4398_DN
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; HL60; HG-U133A	PPFIA3 ADAM12 ARHGEF10 XPNPEP3 HSD17B3 TRAPPC14 MAML3 MED12	2.16e-04	196	186	8	1418_UP
Drug	Chlormezanone [80-77-3]; Down 200; 14.6uM; HL60; HG-U133A	ENPP2 NR1D1 ITPR1 ATM LYN NIPBL TRAPPC9 VCP	2.16e-04	196	186	8	1620_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	COPA PDK1 ABHD2 ITPR1 DIMT1 ARHGEF10 QSER1 TRAPPC9	2.16e-04	196	186	8	990_UP
Drug	Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A	TBC1D30 NUMA1 CHD9 SRSF11 LARS2 ADAM12 DIMT1 EIF3M	2.16e-04	196	186	8	6692_DN
Drug	Oxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A	SYNE1 BEX1 KAT6A THADA CASKIN2 TTC12 TRAPPC14 SOS2	2.16e-04	196	186	8	6309_DN
Drug	Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A	NUMA1 PPFIA3 PACS1 THADA MAN1A2 AKAP9 XPNPEP3 TRAPPC14	2.16e-04	196	186	8	7329_DN
Drug	Metrizamide [31112-62-6]; Up 200; 5uM; PC3; HT_HG-U133A	ANK1 ANK2 NRCAM ENPP2 ABHD2 HPSE2 HUWE1 AKAP9	2.16e-04	196	186	8	4075_UP
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; HL60; HG-U133A	CEP104 RANBP2 PPFIA1 ACIN1 ATM LONRF3 TRAPPC14 VCP	2.16e-04	196	186	8	1995_DN
Drug	Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A	CEP104 PSMD11 ITPR1 ITPR2 LIG3 KAZN QSER1 TRAPPC9	2.24e-04	197	186	8	2848_DN
Drug	AH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A	PHF20 COPA ABHD2 CNTRL PPFIA3 KAZN TRAPPC14 SOS2	2.24e-04	197	186	8	6890_UP
Drug	Meticrane [1084-65-7]; Down 200; 14.6uM; PC3; HT_HG-U133A	ANK3 PPFIA3 ADAM12 CASKIN2 MAP4K5 LYN NIPBL SOS2	2.24e-04	197	186	8	7282_DN
Drug	felodipine; Up 200; 10uM; MCF7; HG-U133A	CYP3A5 ABHD2 PSMD11 EDNRB ITPR2 LIG3 KAZN TRAPPC14	2.24e-04	197	186	8	337_UP
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	SMC1A PSMD11 C2CD2 MDN1 TSR1 DHRS9 PACS2 PUS7	2.24e-04	197	186	8	1180_DN
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; HL60; HG-U133A	RANBP2 STAG1 PDK1 ARHGEF12 SRSF11 NIPBL MAML3 EIF3M	2.24e-04	197	186	8	1441_UP
Drug	Streptozotocin [18883-66-4]; Up 200; 15uM; MCF7; HT_HG-U133A	TBC1D30 AKAP9 TSR1 NDUFAF7 ATM FGD6 TRAPPC9 SOS2	2.24e-04	197	186	8	7193_UP
Drug	Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; PC3; HT_HG-U133A	TBC1D30 CYP3A5 PDK1 ENPP2 NUMA1 EVC MAP4K5 SOS2	2.32e-04	198	186	8	5829_UP
Drug	Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A	ANK3 PACS1 LIG3 AKAP9 CASKIN2 DHRS9 LRP1 MAPK8	2.32e-04	198	186	8	2065_UP
Drug	Cefotetan [69712-56-7]; Down 200; 7uM; MCF7; HT_HG-U133A	CEP104 PHF20 ABHD2 SMC1A CNTRL ARHGEF12 CDK10 MAN1A2	2.32e-04	198	186	8	4116_DN
Drug	Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	TBC1D30 NTRK2 KAT6A NUMA1 NR1D1 CDK10 MAPK8 SOS2	2.32e-04	198	186	8	4343_UP
Drug	Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A	PHF20 CYP3A5 CYP4B1 ENPP2 SYNE1 EDNRB ITPR1 PKNOX2	2.32e-04	198	186	8	5680_UP
Drug	0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A	KAT6A NUMA1 PPFIA3 ADAM12 PACS1 LIG3 CFAP74 SOS2	2.32e-04	198	186	8	6426_UP
Drug	Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A	ABHD2 ARHGEF12 CHD9 SRSF11 AKAP9 XPNPEP3 ATM TRAPPC14	2.32e-04	198	186	8	5304_UP
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	NRCAM CYP3A5 SYNE1 MAN1A2 DIMT1 ARHGEF10 LRP1 MAPK8	2.32e-04	198	186	8	5087_UP
Drug	Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ARHGEF12 PPFIA3 ITPR1 PKNOX2 PACS1 VWA5A KAZN TRAPPC9	2.32e-04	198	186	8	2791_UP
Drug	Caffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A	ANK3 NRCAM ITPR2 PKNOX2 LIG3 TRANK1 DIMT1 TRAPPC9	2.32e-04	198	186	8	3053_UP
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A	PHF20 COPA SMC1A PPFIA3 CDK10 STK10 TSR1 CASKIN2	2.40e-04	199	186	8	5540_UP
Drug	Bromperidol [10457-90-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A	COPA ABHD2 PSMD11 CDK10 ITPR2 MAP4K5 TRAPPC14 NIPBL	2.40e-04	199	186	8	2872_DN
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; PC3; HT_HG-U133A	ABHD2 BEX1 SMC1A SRSF11 RSU1 PACS1 MED4 LYN	2.40e-04	199	186	8	5095_DN
Drug	Furosemide [54-31-9]; Down 200; 12uM; HL60; HG-U133A	GPAA1 PPFIA1 NR1D1 LIG3 DIMT1 CARD9 ACIN1 TRAPPC9	2.40e-04	199	186	8	1580_DN
Drug	Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; PC3; HT_HG-U133A	NUMA1 PACS1 ATM TRAPPC14 NIPBL TRAPPC9 VCP ZNF292	2.40e-04	199	186	8	5838_DN
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A	BEX1 NTRK2 PTGIS LRP1 MIOS MAPK8 RBM34 SOS2	2.40e-04	199	186	8	4533_UP
Drug	Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; HL60; HT_HG-U133A	PPFIA1 NUMA1 ARHGEF12 SRSF11 NR1D1 CDK10 KAZN SOS2	2.48e-04	200	186	8	1263_UP
Drug	Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	PHF20 CYP3A5 NTRK2 PKNOX2 PACS1 LIG3 VWA5A SOS2	2.48e-04	200	186	8	5755_UP
Drug	Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A	PDK1 KAT6A ARHGEF12 ITPR2 CASKIN2 TRAPPC9 RBM34 ZNF292	2.48e-04	200	186	8	5403_DN
Drug	Epiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A	CNTRL NUMA1 PACS1 LONRF3 MAPK8 LYN MED12 SOS2	2.48e-04	200	186	8	5687_DN
Disease	Schizophrenia	ANKK1 PSAT1 RAPGEF6 ANK3 HTR7 CYP3A5 ABCA13 NTRK2 CHD4 LARS2 ADAM12 PKNOX2 EML5 PIK3C3 LRP1 ATM MAPK8 PCDH8 MED12	3.25e-06	883	185	19	C0036341
Disease	Malignant neoplasm of breast	ANK1 ANK2 NRCAM SYNE1 BCAR1 ADAM12 HELQ EDNRB AKAP9 TMTC4 ASL NLRC5 ATM LGR6 LONRF3 FASTKD3 PCDH8 NIPBL EIF3M MED12 NLRP8	4.28e-06	1074	185	21	C0006142
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	3.91e-05	2	185	2	C1140716
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	3.91e-05	2	185	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	3.91e-05	2	185	2	C1527348
Disease	Anoxia of brain	ITPR1 ITPR2	3.91e-05	2	185	2	C0995195
Disease	Colorectal Carcinoma	SALL3 ANK2 NRCAM ABCA13 SYNE1 LIG3 ZNHIT6 AKAP9 WNT16 LRP1 ACIN1 C2CD6 LGR6 NLRP8 ZNF292	3.98e-05	702	185	15	C0009402
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B NRCAM CNTNAP3 CHD9 ARHGEF10 CHD6 GPRASP2	5.11e-05	152	185	7	DOID:0060041 (implicated_via_orthology)
Disease	Bipolar Disorder	ANKK1 ANK3 ABCA13 SYNE1 NTRK2 LARS2 NR1D1 ITPR1 PACS1 TRANK1 ARHGEF10 PIK3C3	5.20e-05	477	185	12	C0005586
Disease	breast ductal carcinoma (is_implicated_in)	RICTOR BCAR1	1.17e-04	3	185	2	DOID:3007 (is_implicated_in)
Disease	Prostatic Neoplasms	CYP3A5 KAT6A BCAR1 ITPR1 JAK1 CHD6 ATM HSD17B3 PCDH8 MED12 GOLGA4 VCP ZNF292	1.48e-04	616	185	13	C0033578
Disease	Malignant neoplasm of prostate	CYP3A5 KAT6A BCAR1 ITPR1 JAK1 CHD6 ATM HSD17B3 PCDH8 MED12 GOLGA4 VCP ZNF292	1.48e-04	616	185	13	C0376358
Disease	body weight	KNTC1 NRCAM NTRK2 ADGRB3 ARHGEF12 ATP13A5 ZSWIM6 HUWE1 PPFIA3 CWC22 RSU1 CDK10 ITPR1 MAP4K5 ASL MICA KAZN NIPBL MAML3	3.84e-04	1261	185	19	EFO_0004338
Disease	colorectal adenoma (is_implicated_in)	PTGIS MAPK8	3.86e-04	5	185	2	DOID:0050860 (is_implicated_in)
Disease	Congenital muscular hypertrophy-cerebral syndrome	SMC1A NIPBL	3.86e-04	5	185	2	C1802395
Disease	Cornelia de Lange Syndrome 3	SMC1A NIPBL	3.86e-04	5	185	2	C1853099
Disease	Cornelia de Lange Syndrome 1	SMC1A NIPBL	3.86e-04	5	185	2	C4551851
Disease	Depressive disorder	ANKK1 HTR7 NTRK2 NR1D1 ARHGEF10 FTL MAPK8 MED12	5.04e-04	289	185	8	C0011581
Disease	De Lange syndrome	SMC1A NIPBL	5.77e-04	6	185	2	cv:C0270972
Disease	Cornelia de Lange syndrome (implicated_via_orthology)	SMC1A NIPBL	5.77e-04	6	185	2	DOID:11725 (implicated_via_orthology)
Disease	Alcohol Related Birth Defect	ANK3 NTRK2	5.77e-04	6	185	2	C3146244
Disease	primary ciliary dyskinesia (is_implicated_in)	STK36 CFAP74	5.77e-04	6	185	2	DOID:9562 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	ANK2 NRCAM KCNU1 LRP1 KCNT1 DYNC1H1	5.89e-04	163	185	6	DOID:1826 (implicated_via_orthology)
Disease	Child Development Disorders, Specific	NTRK2 CHD4 KCNT1	7.86e-04	29	185	3	C0085997
Disease	Child Development Deviations	NTRK2 CHD4 KCNT1	7.86e-04	29	185	3	C0085996
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD6	8.04e-04	7	185	2	DOID:0050834 (implicated_via_orthology)
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK1 ATM	8.04e-04	7	185	2	DOID:14566 (implicated_via_orthology)
Disease	Developmental Disabilities	NTRK2 CHD4 KCNT1	8.69e-04	30	185	3	C0008073
Disease	Manic Disorder	ANK3 NTRK2 PACS1 TRANK1	1.05e-03	71	185	4	C0024713
Disease	Frontotemporal Dementia With Motor Neuron Disease	TBK1 VCP	1.07e-03	8	185	2	C3888102
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.07e-03	8	185	2	DOID:0060308 (implicated_via_orthology)
Disease	Cornelia De Lange Syndrome	SMC1A NIPBL	1.07e-03	8	185	2	C0270972
Disease	testosterone measurement	SLC22A25 ANK2 ANK3 STAG1 TFAP2E CYP4B1 CWC22 RSU1 C2CD2 PKNOX2 THADA ANAPC1 MAP4K5 CNKSR3 C18orf63 KAZN MED12 SOS2	1.15e-03	1275	185	18	EFO_0004908
Disease	intellectual disability (implicated_via_orthology)	ANK2 GPRASP2 TRAPPC9 PUS7	1.28e-03	75	185	4	DOID:1059 (implicated_via_orthology)
Disease	underweight body mass index status	ANK2 ADGRB3	1.37e-03	9	185	2	EFO_0005936
Disease	serine measurement	PACS1 MAP4K5 DYNC1H1	1.37e-03	35	185	3	EFO_0009774
Disease	Manic	ANK3 NTRK2 PACS1 TRANK1	1.49e-03	78	185	4	C0338831
Disease	Depression, Bipolar	ANK3 NTRK2 PACS1 TRANK1	1.56e-03	79	185	4	C0005587
Disease	Alcoholic Intoxication, Chronic	ANKK1 HTR7 NTRK2 PKNOX2 ANAPC1 TTC12 EPHA8	1.57e-03	268	185	7	C0001973
Disease	Essential hypertension	CYP3A5 PTGIS	1.70e-03	10	185	2	cv:C0085580
Disease	Essential hypertension, genetic	CYP3A5 PTGIS	1.70e-03	10	185	2	cv:CN305331
Disease	HYPERTENSION, ESSENTIAL	CYP3A5 PTGIS	1.70e-03	10	185	2	145500
Disease	glycerophosphorylcholine measurement	JAK1 EPHA8	2.07e-03	11	185	2	EFO_0020018
Disease	Intellectual Disability	STAG1 SYNE1 CDK10 PACS1 ACIN1 PACS2 DYNC1H1 PUS7 ZNF292	2.14e-03	447	185	9	C3714756
Disease	age-related macular degeneration, disease progression measurement	CYP4B1 PKNOX2 TRAPPC9	2.17e-03	41	185	3	EFO_0001365, EFO_0008336
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	2.48e-03	12	185	2	DOID:1441 (implicated_via_orthology)
Disease	response to carboplatin, methylcobalamin deficiency type cblE, response to antineoplastic agent	KAZN FGD6	2.48e-03	12	185	2	GO_0097327, GO_0097328, MONDO_0009354
Disease	Essential Hypertension	CYP3A5 PTGIS	2.48e-03	12	185	2	C0085580
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	MAP4K5 ROCK1	2.48e-03	12	185	2	EFO_0800453
Disease	brain disease (is_implicated_in)	RANBP2 TBK1	2.48e-03	12	185	2	DOID:936 (is_implicated_in)
Disease	Neurodevelopmental Disorders	ANK2 SMC1A ITPR1 ZNF292	2.83e-03	93	185	4	C1535926
Disease	alcohol and nicotine codependence	RGPD2 PKNOX2	2.91e-03	13	185	2	EFO_0004776
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	MAP4K5 ROCK1	2.91e-03	13	185	2	OBA_2045082
Disease	bipolar disorder	ANK3 SYNE1 ZSWIM6 HUWE1 PTGIS PACS1 TRANK1 KCNU1 XPNPEP3 PUS7	3.64e-03	577	185	10	MONDO_0004985
Disease	Adenoid Cystic Carcinoma	SMC1A KAT6A ATM MAML3	3.67e-03	100	185	4	C0010606
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	ANK3 SYNE1 CWC22 CDK10	3.81e-03	101	185	4	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	Romano-Ward Syndrome	ANK2 AKAP9	4.43e-03	16	185	2	C0035828
Disease	Intrahepatic cholestasis of pregnancy	MAP4K5 DHRS9	4.43e-03	16	185	2	EFO_0009048
Disease	migraine without aura, susceptibility to, 4	HPSE2 LRP1	4.43e-03	16	185	2	MONDO_0011847
Disease	smoking cessation	ANK3 STAG1 ENPP2 VEPH1 MEI1 TTC12 MAML3	4.57e-03	325	185	7	EFO_0004319
Disease	major depressive disorder (is_implicated_in)	NTRK2 MED12	5.00e-03	17	185	2	DOID:1470 (is_implicated_in)
Disease	level of Phosphatidylcholine (14:0_18:2) in blood serum	MAP4K5 ROCK1	5.00e-03	17	185	2	OBA_2045063
Disease	Ischemic stroke, fibrinogen measurement	RAPGEF6 STAG1 CHD9	5.01e-03	55	185	3	EFO_0004623, HP_0002140
Disease	Mental Depression	ANKK1 HTR7 NTRK2 ARHGEF10 MAPK8 MED12	5.48e-03	254	185	6	C0011570
Disease	essential hypertension (is_implicated_in)	CYP3A5 PTGIS	5.60e-03	18	185	2	DOID:10825 (is_implicated_in)
Disease	migraine disorder, systolic blood pressure	RNF213 HPSE2	5.60e-03	18	185	2	EFO_0006335, MONDO_0005277
Disease	fibrinogen measurement, factor VII measurement	RAPGEF6 STAG1 MAP4K5	5.81e-03	58	185	3	EFO_0004619, EFO_0004623
Disease	insulin resistance	ANK2 KCNU1 MAP4K5	6.09e-03	59	185	3	EFO_0002614
Disease	Noonan-Like Syndrome With Loose Anagen Hair	SHOC2 SOS2	6.23e-03	19	185	2	C3501846
Disease	Noonan syndrome-like disorder with loose anagen hair	SHOC2 SOS2	6.23e-03	19	185	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	SHOC2 SOS2	6.23e-03	19	185	2	C1275081
Disease	sensorineural hearing loss (implicated_via_orthology)	EDNRB SLITRK6	6.23e-03	19	185	2	DOID:10003 (implicated_via_orthology)
Disease	Costello syndrome (disorder)	SHOC2 SOS2	6.23e-03	19	185	2	C0587248
Disease	hydrocephalus (implicated_via_orthology)	STK36 POMK	6.23e-03	19	185	2	DOID:10908 (implicated_via_orthology)
Disease	leukemia (implicated_via_orthology)	PKNOX2 ATM	6.23e-03	19	185	2	DOID:1240 (implicated_via_orthology)
Disease	triglyceride measurement, body mass index	STK36 MAP4K5	6.23e-03	19	185	2	EFO_0004340, EFO_0004530

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLKGALMLENLQKHS	ACIN1	101	Q9UKV3
ALHAQMNGRKITLKR	AKAP9	3096	Q99996
ILLLQDMLKNTSKGH	ARHGEF10	571	O15013
RVIALAHKTLKMGNL	ATP13A5	656	Q4VNC0
KFKAMQSNGILLHRE	CNTNAP3	211	Q9BZ76
LRRKLKLGTGEMNIH	CNTRL	816	Q7Z7A1
LKSLHGTVMKINQER	CNTRL	1001	Q7Z7A1
QLMEKLREKQLSHSL	BEX1	91	Q9HBH7
ALHAKLSRQLQKMED	BCAR1	536	P56945
LLRKNHSIMQLCNSK	ADGRB3	101	O60242
LNDKQKHRLDFLQLM	CYP3A5	261	P20815
ADNMKKIILSHRQAL	ABHD2	261	P08910
KNHVRVMELLLKTGA	ANK1	381	P16157
LKPGNILLDSNMHVK	ANKK1	146	Q8NFD2
AAMRLAKQKSLTQLH	CARNS1	496	A5YM72
RHLLSEMNKGIKSIN	ABCA13	2076	Q86UQ4
LMLLQDSNKKSHIAL	ABCA13	4156	Q86UQ4
KMKLLPRKSHDNAQL	ADAM12	291	O43184
LRKKSGMQIALNDHL	EDNRB	301	P24530
SKLTNNFEKLRLHQM	DEUP1	101	Q05D60
LQLEIDQLKHSLMKA	CARD9	206	Q9H257
LHIGLNEQMKAVRKR	ARHGEF12	841	Q9NZN5
GELHSRKSMLLAAKQ	TFAP2E	336	Q6VUC0
QLGAHLEQLKMTIKS	CFAP206	296	Q8IYR0
HMLLNLSRGKQDFLK	RANBP2	356	P49792
VHLALKLNNSELMGR	RBM34	341	P42696
GMLNDNRKRLLLNLH	QSER1	1586	Q2KHR3
DLMSHLKKQILRTDN	JAK1	521	P23458
ARHNKLLQQMLKPGS	ITPR2	2116	Q14571
MPLLQTLDNLKEGKH	KCTD19	96	Q17RG1
IRMLLNQHSLLFGGK	PDK1	191	Q15118
LRMTLAHIKDQKEGL	MICA	96	Q29983
GNLKVLQLCRFLHMK	ANAPC1	1531	Q9H1A4
HVASKRGNTNMVKLL	ANK2	271	Q01484
LQQLLRDSHLKMLAK	ANKRD27	186	Q96NW4
KHNKIPRSELLNELM	PTCD3	601	Q96EY7
AKHILMQKQRALSDL	MDN1	4116	Q9NU22
MQKQRALSDLFKHLA	MDN1	4121	Q9NU22
IPHLAANLKKMNQAL	HAUS2	156	Q9NVX0
NSLMKRDLEKHLNVS	KAZN	556	Q674X7
AHLSEDQKRLLLMKQ	MAML3	661	Q96JK9
GKALEGMFRKLNHLL	GPAA1	336	O43292
MNQKLLKLENLLRFH	MTIF2	1	P46199
LPLDMAALVHAKKAQ	NRAP	1116	Q86VF7
VARNKLGMAKNEVHL	NRCAM	526	Q92823
RLSNAKKQALHAVMG	GPR162	126	Q16538
LARHNKELQSMLKPG	ITPR1	2171	Q14643
MLRKNQHLRHLDLSK	NLRP8	976	Q86W28
MHLKLKGNLALSQAF	LGR6	446	Q9HBX8
LELKHNSTLKQLMRE	GOLGA4	1986	Q13439
DILKSRLKEGHMNPQ	DST	3146	Q03001
MALEKKLNQALLDLH	FTL	101	P02792
LIKKMGDHLTNLHRL	FTL	141	P02792
NKHVGSNMKLLRVDI	LRP1	2446	Q07954
ARMLDHLNKKELRGQ	PPFIA3	981	O75145
KAGLLTKAEMDQILH	ASL	51	P04424
LGLLHEQNMAKMRLL	EIF3M	266	Q7L2H7
HNGLQMILEDKRILK	EXD1	141	Q8NHP7
QELSELVKNRMKHLG	KCNT1	1121	Q5JUK3
TNKLRNVAKMFAHLL	CWC22	541	Q9HCG8
TGHRLLNMLRKTLKE	C2CD6	71	Q53TS8
LMKCVNHKNIIGLLN	MAPK8	76	P45983
ISGDALKKDLINHMQ	PCDH8	931	O95206
QQMHLVSKLKILRLG	LRRC31	136	Q6UY01
MHQLFRLVLGQKDLS	VEPH1	1	Q14D04
LLMLKQHLKNLCGFS	NIPBL	2546	Q6KC79
LGATHKELMILKEQN	PPFIA1	196	Q13136
ARMLDHLTKKDLRGQ	PPFIA1	991	Q13136
KLHRQALALQMSKQE	KNTC1	1051	P50748
KQLMHEALKLRLNLV	MED12	1526	Q93074
HFLNSMKNKILTQRL	KCNU1	516	A8MYU2
FQELMKLALNQGKIH	MED4	76	Q9NPJ6
PHFLKREGNKLQIML	PACS2	101	Q86VP3
CIIRLIKHDLKMNSG	LIG3	411	P49916
LQREKAAQMHLVLLK	HPSE2	176	Q8WWQ2
HNGMNNIIRLFLKKG	HUWE1	2206	Q7Z6Z7
MNHQALVRKLPDLEK	BPNT2	341	Q9NX62
KANLHALIQMKPALS	RICTOR	781	Q6R327
ALIQMKPALSHLGDK	RICTOR	786	Q6R327
LGHQKKLMLGVKRLA	CASKIN2	606	Q8WXE0
LAALHLMASPKVNKD	NLRC5	521	Q86WI3
HFLKRDANKLQIMLQ	PACS1	181	Q6VY07
GSLKMNNIELHKQGL	MEI1	376	Q5TIA1
LKGALHRALQRKRSM	OR2A2	296	Q6IF42
KLIQDHMAKLQLNLR	KAT6A	751	Q92794
KLPDLRTLNNMHSEK	NR1D1	591	P20393
MQSLLLQRKASGLHE	PDP2	451	Q9P2J9
MLKSENLLGKQIDHL	ATM	1321	Q13315
LLQLSKMAINHTGEK	ATM	1651	Q13315
NCKLLEGLKLMNLEH	CHD9	1006	Q3L8U1
MNLRKTHILQKAPAL	CEP104	871	O60308
GNSVLLHISKLQMKD	CD101	101	Q93033
KLLSRHRNKNTMNGA	C2CD2	676	Q9Y426
QANIKNGKHLLMSIS	CHD6	1771	Q8TD26
HRDLKVSNLLMTDKG	CDK10	161	Q15131
NALLREQLEHMKKAN	CROCC2	171	H7BZ55
RMHSLLIKNLKNEIT	COPA	431	P53621
NVKLAQHALAGMQKL	ARFGEF3	61	Q5TH69
MARLVLKSKNGIHLR	CYP4A22	491	Q5TCH4
RALGITLMGHQKKIL	EPHA8	971	P29322
MSHSREKLLNALEKL	IFIT1B	411	Q5T764
MATLLLFKHQKLLGE	GPAT2	466	Q6NUI2
LHVVLKGSNNDMKVL	ZNHIT6	441	Q9NWK9
NRIKVMELLLKHGAS	ANK3	411	Q12955
ANLMKTLQHDKLVRL	LYN	291	P07948
HIRKLLQKMDRPNGL	MAN1A2	361	O60476
DVVTKKRLRNMLGHL	CDC20B	301	Q86Y33
QLLKVLGTRKLMHVA	DYNC1H1	391	Q14204
HLLLRRQTLAKAMDK	CYP4B1	31	P13584
KKMLNKVNLGHAART	EML5	1726	Q05BV3
QMRLSGKKHLLQELR	EVC	661	P57679
NALMHALTDLRKKNP	HLTF	836	Q14527
LAKKQLLMVRQAALH	CFAP141	61	Q5VU69
ALHLMQNLDTKSKLR	CRYBG1	766	Q9Y4K1
RQAKQIVSSAKMLLH	HELQ	1056	Q8TDG4
AQMELKKSLHGEARI	CCDC198	166	Q9NVL8
QKMLKNLKEGGHRVL	CHD4	1056	Q14839
HMPAALQDFLLLKQK	DHRS9	296	Q9BPW9
QLILKHMESRQKGLI	HSD17B3	166	P37058
LKELRKAAHRNGMKN	SLC22A25	296	Q6T423
TMGNLKQHLLTHRLK	SALL3	1016	Q9BXA9
LKTKMHSDNLLRNDL	PKNOX2	166	Q96KN3
RKNMAPQRKDLHGLS	CFAP74	1131	Q9C0B2
LKTSMIQHDKLNLGP	C18orf63	471	Q68DL7
VGQLMDGLKQLKLHR	ENPP2	336	Q13822
KFKAMQSNGILLHRE	CNTNAP3B	211	Q96NU0
LLARVDHLMKVGKNN	DIMT1	181	Q9UNQ2
KMHRDIKGANILLTD	MAP4K5	136	Q9Y4K4
ILLSILKMHSAKGRQ	OR5T3	251	Q8NGG3
QLSMLKKAHGLLAEE	NUMA1	1436	Q14980
LHGLQLKMSILQSRE	PHF20	756	Q9BVI0
QISSLQKLKHLNLGM	RSU1	81	Q15404
QKLKHLNLGMNRLNT	RSU1	86	Q15404
NQHLAMLAKKLELDR	DROSHA	1006	Q9NRR4
ALRHQTKIMFKNLLQ	THADA	406	Q6YHU6
LEDTKMNGHLRLLNI	RAPGEF6	506	Q8TEU7
KNIVHRDLKLGNMVL	STK40	191	Q8N2I9
RDLKLGNMVLNKRTH	STK40	196	Q8N2I9
DKEINSPNLLKMIRH	SOS2	811	Q07890
RKLILAGNIIHSLMK	SLITRK6	366	Q9H5Y7
LLTSHQNLLRMTKEK	SYNE1	2601	Q8NF91
NKEKLLMISRSHNNL	TMEM200A	456	Q86VY9
QSNIKHMRKQLDRLG	LARS2	151	Q15031
ENHIMSNLRQVGLKK	FILIP1	831	Q7Z7B0
QHTFLKNMGIDVRLK	NDUFAF7	356	Q7L592
HMLLNLSRGKQDFLK	RGPD2	356	P0DJD1
KARMKLTLLHRELQA	PTGIS	121	Q16647
FQMHRALAALKNKPL	FASTKD3	16	Q14CZ7
NARTKFHVLKMLLNL	GPRASP2	731	Q96D09
ALHLGSQLLRELKKM	PSMD11	146	O00231
QMSRLAKLTKAHRQG	PIK3C3	171	Q8NEB9
MQLALFQGIAKKHRA	PPWD1	401	Q96BP3
LDKALELNMLSLKGH	PSAT1	321	Q9Y617
QRLAHLNKCLMNFKL	PUS7	311	Q96PZ0
IHKDPEQLMNTLRKL	POLR2B	576	P30876
DNLKKLRMLDLRHNK	SHOC2	166	Q9UQ13
KNLMQLNLAHNILRK	PRELP	221	P51888
KDDFLHGLQMLKSLQ	POMK	116	Q9H5K3
VLGKKQEALRILQMH	SYCE1L	96	A8MT33
LVSKMLRAVLQSHKN	TDRD7	6	Q8NHU6
HKGLLELNQMRAFKS	L3HYPDH	286	Q96EM0
ILHRDMKPQNILLAK	STK36	121	Q9NRP7
INRKLSAAGMHEALK	HTR7	406	P34969
MKNLVLKLRASSHNL	CNK3/IPCEF1	81	G9CGD6
MKNLVLKLRASSHNL	CNKSR3	81	Q6P9H4
LGDNLMALNHADKLL	CNOT10	546	Q9H9A5
MALNHADKLLQQPKL	CNOT10	551	Q9H9A5
MRKNIKGIHTLLQNL	NTRK2	796	Q16620
LHMLQRKLGRKLNPE	SPATA4	216	Q8NEY3
LKDLEQLAKMLGHSA	RNF213	4621	Q63HN8
VLHKDKSLENLGMLR	TMTC4	251	Q5T4D3
LLFKQKSNGMHSLIA	TSR1	666	Q2NL82
KSLEHLRKQMQDALL	TRIM11	141	Q96F44
DQKLLLAGMHRNLAI	MIOS	196	Q9NXC5
QLLKLMSTVDPKLNH	SRSF11	186	Q05519
SQLLTLMDGLKQRAH	VCP	326	P55072
GRLEILQIHTKNMKL	VCP	376	P55072
TGLFELSQHMKLKLQ	TRAPPC14	461	Q8WVR3
KRIIHRDLKAGNVLM	STK10	151	O94804
PSRKIMLNLEGHKQE	FGD6	71	Q6ZV73
LLDMRIKHLIKTNQL	ZNF292	191	O60281
RHNLLQACKMQDIKL	SMC1A	926	Q14683
TGRMEKHLDALLKQI	STAG1	606	Q8WVM7
HRLAAKSLLQTKDMG	VWA5A	546	O00534
TGKENKVLLAMNLHN	WNT16	191	Q9UBV4
NSSPVINHLLLGKKM	TBC1D30	676	Q9Y2I9
GKLHTQPKLAAQLRM	VILL	371	O15195
PDNMLLDKSGHLKLA	ROCK1	201	Q13464
LHGRRNSGKLMSLDK	ZSWIM6	1121	Q9HCJ5
RHKLMSLIQKEAQGQ	XPNPEP3	76	Q9NQH7
KKLMHQAALLGQALC	TXNRD3	211	Q86VQ6
ILNGLHEEMLNLKKL	USP10	531	Q14694
HEEMLNLKKLLSPSN	USP10	536	Q14694
LRKLHGLEILNSTMK	TTC12	686	Q9H892
LFAQKRTMLEHLKNT	ZNF687	866	Q8N1G0
SLRPHKMKSLLGQNV	TRAPPC9	551	Q96Q05
LHLLEDLSIKNKQRM	YIPF7	11	Q8N8F6
MTDQVKLALNKHLLG	TRANK1	2116	O15050
RKMLHLRKQLLSLTN	TBK1	621	Q9UHD2
KLSLKNRILNHFGPM	LONRF3	686	Q496Y0