Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF490 ZNF12 ZNF263 SATB2 ZNF211 ZNF354A ZNF33B ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	1.24e-11	1244	52	20	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF490 ZNF12 ZNF263 SATB2 ZNF211 ZNF354A ZNF33B ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	1.82e-11	1271	52	20	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF490 ZNF12 ZNF263 SATB2 ZNF211 ZNF354A ZNF33B ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	1.21e-10	1412	52	20	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF490 ZNF12 ZNF263 SATB2 ZNF211 ZNF354A ZNF33B ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.16e-10	1459	52	20	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF263 ZFP3 ZNF433 ZNF239 ZNF572	1.44e-03	320	52	5	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF263 ZFP3 ZNF433 ZNF239 ZNF572	1.56e-03	326	52	5	GO:0001217
GeneOntologyCellularComponent	HULC complex	RNF20 RNF40	3.63e-05	4	52	2	GO:0033503
GeneOntologyCellularComponent	ubiquitin conjugating enzyme complex	RNF20 RNF40	2.16e-04	9	52	2	GO:0031371
HumanPheno	Infection-related seizure	DMXL2 SATB2 ADGRV1 MBD5 TBCD	2.84e-05	145	14	5	HP:0032892
HumanPheno	Seizure precipitated by febrile infection	DMXL2 SATB2 ADGRV1 MBD5 TBCD	2.84e-05	145	14	5	HP:0032894
HumanPheno	Febrile seizure (within the age range of 3 months to 6 years)	DMXL2 SATB2 ADGRV1 MBD5 TBCD	2.84e-05	145	14	5	HP:0002373
Domain	zf-C2H2	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.71e-17	693	51	21	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.79e-17	694	51	21	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.57e-16	775	51	21	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.71e-16	777	51	21	PS00028
Domain	-	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF239 ZNF572 ZNF71	3.33e-16	679	51	20	3.30.160.60
Domain	Znf_C2H2-like	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	4.39e-16	796	51	21	IPR015880
Domain	Znf_C2H2	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	5.50e-16	805	51	21	IPR007087
Domain	ZnF_C2H2	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZFHX4 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	5.93e-16	808	51	21	SM00355
Domain	KRAB	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZNF354B ZNF568 ZNF433 ZNF783 ZNF829 ZNF287	9.37e-12	358	51	13	PS50805
Domain	KRAB	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZNF354B ZNF568 ZNF433 ZNF783 ZNF829 ZNF287	9.37e-12	358	51	13	PF01352
Domain	KRAB	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZNF354B ZNF568 ZNF433 ZNF783 ZNF829 ZNF287	1.37e-11	369	51	13	SM00349
Domain	KRAB	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZNF354B ZNF568 ZNF433 ZNF783 ZNF829 ZNF287	1.42e-11	370	51	13	IPR001909
Domain	zf-C2H2_6	ZNF490 ZNF12 ZNF211 ZNF354A ZNF155 RREB1 ZNF354B ZNF568 ZNF433 ZNF572 ZNF71	6.67e-10	314	51	11	PF13912
Domain	zf-C2H2_11	ZNF354A ZNF354B	2.60e-04	9	51	2	PF16622
Domain	SCAN	ZNF263 ZNF165 ZNF287	4.80e-04	56	51	3	SM00431
Domain	SCAN_BOX	ZNF263 ZNF165 ZNF287	5.32e-04	58	51	3	PS50804
Domain	SCAN	ZNF263 ZNF165 ZNF287	5.32e-04	58	51	3	PF02023
Domain	SCAN_dom	ZNF263 ZNF165 ZNF287	5.32e-04	58	51	3	IPR003309
Domain	Retrov_capsid_C	ZNF263 ZNF165 ZNF287	5.60e-04	59	51	3	IPR008916
Domain	Znf_RING_CS	TRAF5 RNF20 RNF40	1.00e-02	163	51	3	IPR017907
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF490 ZNF12 ZNF263 SATB2 ZNF211 SETD1B ZNF354A ZNF33B ZNF155 ZNF354B ZNF568 ZNF433 ZNF287 ZNF71	2.37e-06	1387	35	14	M734
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	ZNF490 SETD1B ZNF354A ZNF433	3.44e-04	136	35	4	MM14848
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF490 ZNF354A ZNF433	3.55e-04	56	35	3	MM17236
Pathway	REACTOME_PROTEIN_UBIQUITINATION	UBA1 RNF20 RNF40	5.51e-04	65	35	3	MM15490
Pathway	REACTOME_PROTEIN_UBIQUITINATION	UBA1 RNF20 RNF40	9.74e-04	79	35	3	M27742
Pubmed	E3 Ubiquitin Ligases RNF20 and RNF40 Are Required for Double-Stranded Break (DSB) Repair: Evidence for Monoubiquitination of Histone H2B Lysine 120 as a Novel Axis of DSB Signaling and Repair.	RNF20 RNF40	2.19e-06	2	52	2	30692271
Pubmed	A molecular model for neurodevelopmental disorders.	SATB2 MBD5	2.19e-06	2	52	2	25966365
Pubmed	Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.	RNF20 RNF40	2.19e-06	2	52	2	22354749
Pubmed	RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease.	RNF20 RNF40	2.19e-06	2	52	2	34088983
Pubmed	Identification of two new mutations in the GPR98 and the PDE6B genes segregating in a Tunisian family.	PDE6B ADGRV1	2.19e-06	2	52	2	18854872
Pubmed	RNF20/RNF40 ameliorates streptozotocin-induced type 1 diabetes by activating vitamin D receptors in vivo.	RNF20 RNF40	2.19e-06	2	52	2	37422774
Pubmed	Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.	RNF20 RNF40	2.19e-06	2	52	2	20738173
Pubmed	Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2.	ZNF354A ZNF354B	2.19e-06	2	52	2	10564808
Pubmed	A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains.	PDE6B ADGRV1	2.19e-06	2	52	2	29961073
Pubmed	Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation.	RNF20 RNF40	2.19e-06	2	52	2	34290256
Pubmed	The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.	RNF20 RNF40	6.57e-06	3	52	2	22021426
Pubmed	RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.	RNF20 RNF40	6.57e-06	3	52	2	21827756
Pubmed	The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer.	RNF20 RNF40	6.57e-06	3	52	2	27798111
Pubmed	Proteomic identification of RREB1, PDE6B, and CD209 up-regulated in primitive gut tube differentiated from human embryonic stem cells.	PDE6B RREB1	6.57e-06	3	52	2	21792086
Pubmed	Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth.	RNF20 RNF40	6.57e-06	3	52	2	22155569
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF490 ZNF211 ZNF354A ZNF33B ZNF354B	7.70e-06	181	52	5	37372979
Pubmed	Ring finger 20/ring finger 40/WW domain-containing adaptor with coiled-coil complex interacts with p53 to regulate gene transcription in DNA damage response.	RNF20 RNF40	1.31e-05	4	52	2	33868474
Pubmed	Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.	PDE6B ADGRV1	1.31e-05	4	52	2	37127773
Pubmed	Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination.	RNF20 RNF40	1.31e-05	4	52	2	28453857
Pubmed	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.	RNF20 RNF40	1.31e-05	4	52	2	26781088
Pubmed	Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.	RNF20 RNF40	1.31e-05	4	52	2	21362549
Pubmed	Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.	RNF20 RNF40	1.31e-05	4	52	2	38517892
Pubmed	Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.	RNF20 RNF40	1.31e-05	4	52	2	32672815
Pubmed	SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms.	RNF20 RNF40	1.31e-05	4	52	2	24441044
Pubmed	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks.	RNF40 TBCD	2.19e-05	5	52	2	33875784
Pubmed	WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription.	RNF20 RNF40	2.19e-05	5	52	2	21329877
Pubmed	Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.	RNF20 RNF40	3.28e-05	6	52	2	27569044
Pubmed	The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair.	RNF20 RNF40	3.28e-05	6	52	2	37155876
Pubmed	RNF20/40-mediated eEF1BδL monoubiquitylation stimulates transcription of heat shock-responsive genes.	RNF20 RNF40	4.58e-05	7	52	2	30649429
Pubmed	Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.	RNF20 RNF40	4.58e-05	7	52	2	27557628
Pubmed	The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination.	RNF20 RNF40	4.58e-05	7	52	2	24526689
Pubmed	CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing.	RNF20 RNF40	4.58e-05	7	52	2	19575011
Pubmed	Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation.	RNF20 RNF40	4.58e-05	7	52	2	22252316
Pubmed	Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.	RNF20 RNF40	7.84e-05	9	52	2	25533843
Pubmed	Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.	RNF20 RNF40	9.79e-05	10	52	2	37633270
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	UBA1 RNF20 EIF3A	1.12e-04	62	52	3	26508657
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DMXL2 UBA1 RNF40 EIF3A TBCD	1.20e-04	322	52	5	26514267
Pubmed	H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb.	RNF20 RNF40	1.43e-04	12	52	2	24837678
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	MYO3B ADGRV1	1.97e-04	14	52	2	26754646
Pubmed	RREB1 regulates neuronal proteostasis and the microtubule network.	FARS2 RREB1	2.60e-04	16	52	2	38198538
Pubmed	Genome-wide association of body fat distribution in African ancestry populations suggests new loci.	SATB2 RREB1	2.60e-04	16	52	2	23966867
Pubmed	RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.	RNF20 RNF40	3.30e-04	18	52	2	19410543
Pubmed	CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression.	RNF20 RNF40	3.30e-04	18	52	2	29507117
Pubmed	Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn.	SATB2 PTGFR	3.69e-04	19	52	2	38452762
Pubmed	Genome-wide association with bone mass and geometry in the Framingham Heart Study.	ERC2 ADGRV1	3.69e-04	19	52	2	17903296
Pubmed	LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function.	RNF20 RNF40	3.69e-04	19	52	2	31186351
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBA1 RNF20 RNF40	3.96e-04	95	52	3	29643511
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SATB2 ZFHX4 RNF40 RREB1 GTF3C3	4.00e-04	418	52	5	34709266
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	SATB2 SETD1B ZFHX4 ERC2 ADGRV1	4.60e-04	431	52	5	33660365
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	RNF40 ADGRV1 ZNF623	4.88e-04	102	52	3	9734811
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1B LSG1 RNF20 RNF40 GTF3C3	5.05e-04	440	52	5	34244565
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SATB2 UBA1 RNF20 ERC2 RNF40	5.26e-04	444	52	5	34795231
Pubmed	Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.	SATB2 RNF20	5.44e-04	23	52	2	36103829
Pubmed	Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.	RNF20 RNF40	5.44e-04	23	52	2	16307923
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DMXL2 UBA1 ERC2 LRRC7	5.46e-04	251	52	4	27507650
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZNF263 DMXL2 UBA1 MDN1 LSG1 ERC2 LRRC7	5.52e-04	963	52	7	28671696
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	DMXL2 MDN1 ZNF155 RNF20 MBD5 TBCD	5.55e-04	689	52	6	36543142
Pubmed	Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.	SATB2 EIF3A	5.93e-04	24	52	2	25157170
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	MDN1 GTF3C3 ZNF829	7.09e-04	116	52	3	21549307
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	SATB2 ZFHX4	8.08e-04	28	52	2	29365100
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UBA1 SETD1B MDN1 LSG1 RNF20 EIF3A AARSD1 GTF3C3	8.43e-04	1353	52	8	29467282
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SATB2 RREB1 GTF3C3	8.81e-04	125	52	3	32891193
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF12 ZNF33B	9.92e-04	31	52	2	2288909
Pubmed	Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.	SATB2 ZFHX4	1.06e-03	32	52	2	36596814
Pubmed	KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.	RNF20 RNF40	1.12e-03	33	52	2	25582440
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	MDN1 RNF20 RNF40 EIF3A AARSD1	1.24e-03	538	52	5	28524877
Pubmed	Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.	DMXL2 SATB2	1.26e-03	35	52	2	37758766
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	MDN1 EIF3A	1.26e-03	35	52	2	24515614
Pubmed	Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma.	RNF20 RNF40	1.26e-03	35	52	2	30942445
Interaction	YJU2B interactions	ZNF12 ZFP3 ZNF165 ZNF572	1.79e-05	63	50	4	int:YJU2B
Interaction	KRTAP10-9 interactions	ZNF490 ZNF155 ZNF165 FARS2 ZNF433 ZNF572	2.81e-05	241	50	6	int:KRTAP10-9
Interaction	KRTAP10-7 interactions	ZNF490 ZNF155 ZNF165 FARS2 ZNF433 ZNF572	8.33e-05	293	50	6	int:KRTAP10-7
Interaction	KRTAP10-3 interactions	ZNF490 ZNF155 ZNF165 FARS2 ZNF433 ZNF572	8.49e-05	294	50	6	int:KRTAP10-3
Interaction	INSL4 interactions	SGSH ADGRV1	8.99e-05	6	50	2	int:INSL4
Cytoband	Ensembl 112 genes in cytogenetic band chr1p31	LRRC7 CACHD1 PTGFR	2.12e-03	224	52	3	chr1p31
Cytoband	19p13.2	ZNF490 ZNF653 ZNF433	2.26e-03	229	52	3	19p13.2
Cytoband	1p31.1	LRRC7 PTGFR	2.97e-03	71	52	2	1p31.1
Cytoband	19q13.12	ZNF568 ZNF829	3.06e-03	72	52	2	19q13.12
Cytoband	19q13.4	ZNF211 ZNF71	3.67e-03	79	52	2	19q13.4
Cytoband	5q35.3	ZNF354A ZNF354B	5.25e-03	95	52	2	5q35.3
Cytoband	17q25.3	SGSH TBCD	5.92e-03	101	52	2	17q25.3
Cytoband	8q24.3	ZNF623 OPLAH	7.35e-03	113	52	2	8q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	ZNF623 OPLAH ZNF572	7.66e-03	355	52	3	chr8q24
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF490 ZNF12 ZNF263 ZNF211 ZNF354A ZNF33B ZNF155 ZFP3 ZNF165 RREB1 ZNF623 ZNF354B ZNF653 ZNF568 ZNF433 ZNF783 ZNF829 ZNF287 ZNF239 ZNF572 ZNF71	2.42e-18	718	44	21	28
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	ZNF263 TRAF5 ZNF211 ZNF354A ZNF71	3.62e-06	200	52	5	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
Disease	hip geometry	ERC2 ADGRV1	2.54e-03	44	50	2	EFO_0004685
Disease	major depressive episode	SATB2 SETD1B	2.90e-03	47	50	2	EFO_0007634
Disease	complement factor H-related protein 1 measurement	MYO3B CATSPER3	4.09e-03	56	50	2	EFO_0600054
Disease	cutaneous melanoma, hair color	ADGRV1 RREB1	4.99e-03	62	50	2	EFO_0000389, EFO_0003924

Protein segments in the cluster

Peptide	Gene	Start	Entry
REMRHLISSLQNHNH	RNF40	481	O75150
MRHLISSLQNHNHQL	RNF20	476	Q5VTR2
MSQHRHQRHSRVISS	CATSPER3	1	Q86XQ3
PQRIHHMAASHVNIT	AFF2	1236	P51816
TVHLQQHMRRHHSGT	ADGRV1	1311	Q8WXG9
IHRRSHQHMSPLAAQ	CACHD1	1121	Q5VU97
RRFDHMQQHSGQHLI	AARSD1	101	Q9BTE6
RNLHNVKRMTSHPVH	DMXL2	2761	Q8TDJ6
MNHGFVHHIRRNQIA	C2orf68	21	Q2NKX9
AHITGHRLRVVNMNQ	MDN1	691	Q9NU22
LMRHQTQRSRSHRHT	LSG1	16	Q9H089
HIQTLMGSQSLQHRS	LRRC7	1376	Q96NW7
QHRQGRSHHLEMVIQ	PTGFR	236	P43088
QNLNRRQHEHVIHLM	PDE6B	646	P35913
TTGQHLHHALRMLQS	PLK5	321	Q496M5
HHHQVPSMLRQVRDS	ERC2	131	O15083
LRMHLSQIQRHHNQS	EIF3A	201	Q14152
HMNHGSHVQRVQHSA	MBD5	416	Q9P267
SLRRHTQRMQHNGHS	TAS2R41	206	P59536
HGRSGVHSHMTNTRI	OPLAH	1131	O14841
TQHTQKMSVHRIITH	PRSS47P	146	A8MTI9
RHHHSERMQHVVQLP	SATB2	561	Q9UPW6
VQHLHSTSVMGNIIH	SETD1B	161	Q9UPS6
MRSVQHRHFRLVHNL	SGSH	376	P51688
RNLQQHEHSALREHM	TRAF5	236	O00463
FNQVTMHSQDVRHHR	GTF3C3	706	Q9Y5Q9
NSSHLIQHLRMHTGE	ZNF572	171	Q7Z3I7
LSNHLRRHMIIHSGV	ZNF653	511	Q96CK0
SRDQSRIQMHVLSQH	ZFHX4	1181	Q86UP3
CMNSHLTVHQRTHTG	ZNF33B	451	Q06732
RHISSLIAHQRMHTG	ZNF287	406	Q9HBT7
AFIQMSNLIRHHRIH	ZNF568	286	Q3ZCX4
MHQVSLNRHMRSHTE	ZNF490	166	Q9ULM2
TTQHQLTMHIRQHNT	RREB1	76	Q92766
SQRSNLMQHRRVHTG	ZNF211	351	Q13398
VRQMNPHIRVTSHQN	UBA1	536	P22314
TQHSRLIQHQRMHTG	ZNF829	306	Q3KNS6
SQSSNLSQHQRIHMR	ZNF165	466	P49910
HQRSALNRHCMVHTG	ZNF155	326	Q12901
LRHLHLISSHSRQQM	TBCD	711	Q9BTW9
FNSHQRIHRRGNMNV	ZNF12	676	P17014
RQSSALIQHQRMHTG	ZNF354A	476	O60765
RQSSALIQHQRMHTG	ZNF354B	476	Q96LW1
MSFSQRSNLHIHQRV	ZNF239	326	Q16600
GQSSHLMEHQRIHTG	ZNF623	161	O75123
LNRTHMLRAHTSAHQ	FARS2	146	O95363
SHSNLQRHRIMHRGD	ZNF433	181	Q8N7K0
SQRMNLTVHQRTHTG	ZNF71	196	Q9NQZ8
FSQNMHLIVHQRTHT	ZNF71	251	Q9NQZ8
QNMHLTEHQRTHTGE	ZNF71	281	Q9NQZ8
RTFNRNHHLAVHMQT	ZNF783	501	Q6ZMS7
NQNSHLIQHMRVHSG	ZFP3	151	Q96NJ6
QGMHLTRHQRTHTGE	ZNF263	586	O14978
HQNPVAKTRHERMHT	MYO3B	316	Q8WXR4