Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	RIMS1 RIMS2	3.25e-04	8	69	2	GO:0098882
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RASA4 SRGAP1 SBF2 IQSEC2 OBSCN RASA4B RIMS1 DNMBP	3.51e-04	507	69	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RASA4 SRGAP1 SBF2 IQSEC2 OBSCN RASA4B RIMS1 DNMBP	3.51e-04	507	69	8	GO:0030695
GeneOntologyMolecularFunction	structural constituent of synapse	SPTBN2 RIMS1 RIMS2	4.12e-04	42	69	3	GO:0098918
GeneOntologyBiologicalProcess	establishment of cell polarity involved in ameboidal cell migration	AMOTL1 AMOTL2	3.40e-05	3	70	2	GO:0003365
GeneOntologyBiologicalProcess	synaptic vesicle exocytosis	CACNA1A SPTBN2 RIMS1 RIMS2 STX11	6.66e-05	125	70	5	GO:0016079
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	CACNA1A RIMS1 RIMS2	8.16e-05	25	70	3	GO:0048791
GeneOntologyBiologicalProcess	positive regulation of dendrite extension	NEDD4L RIMS1 RIMS2	1.57e-04	31	70	3	GO:1903861
GeneOntologyBiologicalProcess	synaptic vesicle fusion to presynaptic active zone membrane	RIMS1 RIMS2 STX11	1.57e-04	31	70	3	GO:0031629
GeneOntologyBiologicalProcess	vesicle fusion to plasma membrane	RIMS1 RIMS2 STX11	1.73e-04	32	70	3	GO:0099500
GeneOntologyBiologicalProcess	calcium-ion regulated exocytosis	CACNA1A CACNA1I RIMS1 RIMS2	1.74e-04	82	70	4	GO:0017156
GeneOntologyBiologicalProcess	regulation of dendrite extension	NEDD4L RIMS1 RIMS2	2.27e-04	35	70	3	GO:1903859
GeneOntologyBiologicalProcess	regulation of calcium-dependent activation of synaptic vesicle fusion	RIMS1 RIMS2	2.36e-04	7	70	2	GO:0150037
GeneOntologyBiologicalProcess	synaptic vesicle membrane organization	RIMS1 RIMS2 STX11	2.47e-04	36	70	3	GO:0048499
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex assembly	SPTBN5 CPTP SPTBN1 SPTBN2 DDX3X	3.05e-04	173	70	5	GO:0031333
GeneOntologyBiologicalProcess	cerebellar Purkinje cell layer development	CACNA1A SPTBN2 SEZ6L2	3.13e-04	39	70	3	GO:0021680
GeneOntologyBiologicalProcess	regulated exocytosis	CACNA1A SPTBN2 CACNA1I RIMS1 RIMS2 STX11	4.61e-04	291	70	6	GO:0045055
GeneOntologyBiologicalProcess	positive regulation of inhibitory postsynaptic potential	RIMS1 RIMS2	5.02e-04	10	70	2	GO:0097151
GeneOntologyBiologicalProcess	dendrite extension	NEDD4L RIMS1 RIMS2	5.12e-04	46	70	3	GO:0097484
GeneOntologyBiologicalProcess	actin filament capping	SPTBN5 SPTBN1 SPTBN2	5.12e-04	46	70	3	GO:0051693
GeneOntologyBiologicalProcess	signal release from synapse	CACNA1A SPTBN2 RIMS1 RIMS2 STX11	5.28e-04	195	70	5	GO:0099643
GeneOntologyBiologicalProcess	neurotransmitter secretion	CACNA1A SPTBN2 RIMS1 RIMS2 STX11	5.28e-04	195	70	5	GO:0007269
GeneOntologyCellularComponent	spectrin	SPTBN5 SPTBN1 SPTBN2	2.73e-06	9	68	3	GO:0008091
GeneOntologyCellularComponent	cell cortex region	SPTBN5 IQSEC2 RIMS1 RIMS2	1.38e-05	45	68	4	GO:0099738
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	IQSEC2 RIMS1 RIMS2	5.56e-05	23	68	3	GO:0098831
GeneOntologyCellularComponent	cortical cytoskeleton	SPTBN5 SPTBN1 SPTBN2 RIMS1 RIMS2	6.32e-05	129	68	5	GO:0030863
GeneOntologyCellularComponent	presynaptic active zone	CACNA1A IQSEC2 RIMS1 RIMS2 STX11	9.63e-05	141	68	5	GO:0048786
GeneOntologyCellularComponent	microtubule associated complex	SPTBN5 TPR HAUS1 KIF19 KIF5A	1.79e-04	161	68	5	GO:0005875
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	RIMS1 RIMS2	2.88e-04	8	68	2	GO:0048788
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTBN1 SPTBN2	3.70e-04	9	68	2	GO:0014731
GeneOntologyCellularComponent	presynaptic cytoskeleton	RIMS1 RIMS2	9.25e-04	14	68	2	GO:0099569
GeneOntologyCellularComponent	cytoplasmic region	SPTBN5 IQSEC2 KIF19 KIF5A RIMS1 RIMS2	1.12e-03	360	68	6	GO:0099568
GeneOntologyCellularComponent	cell cortex	SPTBN5 SPTBN1 IQSEC2 SPTBN2 RIMS1 RIMS2	1.30e-03	371	68	6	GO:0005938
GeneOntologyCellularComponent	photoreceptor ribbon synapse	IQSEC2 RIMS2	1.54e-03	18	68	2	GO:0098684
GeneOntologyCellularComponent	presynaptic active zone membrane	CACNA1A RIMS1 STX11	2.10e-03	78	68	3	GO:0048787
Domain	PH_dom-spectrin-type	SPTBN5 SPTBN1 SPTBN2	4.17e-06	9	70	3	IPR001605
Domain	Sp1_fam	SP8 SP3 SP7	5.94e-06	10	70	3	IPR030450
Domain	PH	SPTBN5 RASA4 SBF2 SPTBN1 IQSEC2 SPTBN2 OBSCN RASA4B	9.25e-06	278	70	8	SM00233
Domain	PH_DOMAIN	SPTBN5 RASA4 SBF2 SPTBN1 IQSEC2 SPTBN2 OBSCN RASA4B	9.50e-06	279	70	8	PS50003
Domain	PH_domain	SPTBN5 RASA4 SBF2 SPTBN1 IQSEC2 SPTBN2 OBSCN RASA4B	9.75e-06	280	70	8	IPR001849
Domain	PH	SPTBN5 RASA4 SBF2 SPTBN1 SPTBN2 OBSCN RASA4B	2.36e-05	229	70	7	PF00169
Domain	Angiomotin_C	AMOTL1 AMOTL2	4.14e-05	3	70	2	IPR024646
Domain	Angiomotin	AMOTL1 AMOTL2	4.14e-05	3	70	2	IPR009114
Domain	-	RASA4 RASA4B	4.14e-05	3	70	2	4.10.1130.10
Domain	Angiomotin_C	AMOTL1 AMOTL2	4.14e-05	3	70	2	PF12240
Domain	Spectrin_bsu	SPTBN1 SPTBN2	8.27e-05	4	70	2	IPR016343
Domain	Actinin_actin-bd_CS	SPTBN5 SPTBN1 SPTBN2	8.46e-05	23	70	3	IPR001589
Domain	Spectrin	SPTBN5 SPTBN1 SPTBN2	8.46e-05	23	70	3	PF00435
Domain	ACTININ_2	SPTBN5 SPTBN1 SPTBN2	8.46e-05	23	70	3	PS00020
Domain	ACTININ_1	SPTBN5 SPTBN1 SPTBN2	8.46e-05	23	70	3	PS00019
Domain	-	SPTBN5 RASA4 SBF2 SPTBN1 IQSEC2 SPTBN2 OBSCN RASA4B	1.04e-04	391	70	8	2.30.29.30
Domain	C2	NEDD4L RASA4 RASA4B RIMS1 RIMS2	1.32e-04	131	70	5	PF00168
Domain	C2	NEDD4L RASA4 RASA4B RIMS1 RIMS2	1.63e-04	137	70	5	SM00239
Domain	Spectrin_repeat	SPTBN5 SPTBN1 SPTBN2	1.72e-04	29	70	3	IPR002017
Domain	PH_dom-like	SPTBN5 RASA4 SBF2 SPTBN1 IQSEC2 SPTBN2 OBSCN RASA4B	1.88e-04	426	70	8	IPR011993
Domain	C2	NEDD4L RASA4 RASA4B RIMS1 RIMS2	1.93e-04	142	70	5	PS50004
Domain	Spectrin/alpha-actinin	SPTBN5 SPTBN1 SPTBN2	2.31e-04	32	70	3	IPR018159
Domain	SPEC	SPTBN5 SPTBN1 SPTBN2	2.31e-04	32	70	3	SM00150
Domain	-	NEDD4L RASA4 RASA4B RIMS1 RIMS2	2.34e-04	148	70	5	2.60.40.150
Domain	C2_dom	NEDD4L RASA4 RASA4B RIMS1 RIMS2	3.75e-04	164	70	5	IPR000008
Domain	BTK	RASA4 RASA4B	4.90e-04	9	70	2	SM00107
Domain	Znf_Btk_motif	RASA4 RASA4B	4.90e-04	9	70	2	IPR001562
Domain	BTK	RASA4 RASA4B	4.90e-04	9	70	2	PF00779
Domain	ZF_BTK	RASA4 RASA4B	4.90e-04	9	70	2	PS51113
Domain	VDCCAlpha1	CACNA1A CACNA1I	6.11e-04	10	70	2	IPR002077
Domain	FYVE_2	RIMS1 RIMS2	7.45e-04	11	70	2	PF02318
Domain	RABBD	RIMS1 RIMS2	8.92e-04	12	70	2	PS50916
Domain	Rab_BD	RIMS1 RIMS2	8.92e-04	12	70	2	IPR010911
Domain	RasGAP	RASA4 RASA4B	1.22e-03	14	70	2	SM00323
Domain	RasGAP_CS	RASA4 RASA4B	1.22e-03	14	70	2	IPR023152
Domain	RasGAP	RASA4 RASA4B	1.41e-03	15	70	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA4 RASA4B	1.41e-03	15	70	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA4 RASA4B	1.41e-03	15	70	2	PS50018
Domain	-	RASA4 RASA4B	1.61e-03	16	70	2	1.10.506.10
Domain	CH	SPTBN5 SPTBN1 SPTBN2	1.86e-03	65	70	3	SM00033
Domain	RasGAP_dom	RASA4 RASA4B	2.04e-03	18	70	2	IPR001936
Domain	CH	SPTBN5 SPTBN1 SPTBN2	2.31e-03	70	70	3	PF00307
Domain	-	SPTBN5 SPTBN1 SPTBN2	2.40e-03	71	70	3	1.10.418.10
Domain	CH	SPTBN5 SPTBN1 SPTBN2	2.60e-03	73	70	3	PS50021
Domain	CH-domain	SPTBN5 SPTBN1 SPTBN2	2.81e-03	75	70	3	IPR001715
Domain	zf-C2H2	SP8 ZNF131 SP3 ZNF142 MZF1 TRPS1 SP7 ZNF646	4.29e-03	693	70	8	PF00096
Domain	Rho_GTPase_activation_prot	RASA4 SRGAP1 RASA4B	4.41e-03	88	70	3	IPR008936
Domain	Znf_FYVE-rel	RIMS1 RIMS2	7.19e-03	34	70	2	IPR017455
Domain	ZINC_FINGER_C2H2_2	SP8 ZNF131 SP3 ZNF142 MZF1 TRPS1 SP7 ZNF646	8.27e-03	775	70	8	PS50157
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTBN1 SPTBN2	4.66e-06	10	49	3	MM15112
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN5 SPTBN1 SPTBN2 CACNA1I	6.60e-05	63	49	4	M11187
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTBN1 SPTBN2	1.66e-04	31	49	3	M877
Pathway	BIOCARTA_TERT_PATHWAY	SP3 MZF1	2.46e-04	7	49	2	MM1541
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN5 SPTBN1 SPTBN2	3.06e-04	38	49	3	MM14969
Pathway	BIOCARTA_TERT_PATHWAY	SP3 MZF1	3.27e-04	8	49	2	M22015
Pubmed	C-terminal splice variants of P/Q-type Ca2+ channel CaV2.1 α1 subunits are differentially regulated by Rab3-interacting molecule proteins.	CACNA1A RIMS1 RIMS2	8.51e-09	3	72	3	28377503
Pubmed	Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia.	CACNA1A RIMS1 RIMS2	8.48e-08	5	72	3	33539324
Pubmed	Angiomotin functions in HIV-1 assembly and budding.	NEDD4L AMOTL1 AMOTL2	1.69e-07	6	72	3	25633977
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TPR SNW1 SRGAP1 ZC3H13 KCTD10 SPTBN1 SPTBN2 AMOTL1 CWC22 DNTTIP2 DDX3X NSD3 CPSF7 NCOA5	2.55e-07	1257	72	14	36526897
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1A RIMS1 RIMS2	2.96e-07	7	72	3	35176221
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TPR RSBN1 ZNF131 SNW1 ZC3H13 NFRKB CHD1 CWC22 DNTTIP2 DDX3X NSD3 CPSF7	5.74e-07	954	72	12	36373674
Pubmed	NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.	NEDD4L AMOTL1 AMOTL2	1.01e-06	10	72	3	33058421
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SNW1 NEDD4L USP42 ZC3H13 KCTD10 SPTBN1 SPTBN2 CWC22 DDX3X NSD3 CPSF7 NCOA5	2.13e-06	1082	72	12	38697112
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN5 SPTBN1 SPTBN2	2.40e-06	13	72	3	18796539
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RSBN1 TGM1 FAM193A MZF1 CEP85L SPTBN1 IQSEC2 SPTBN2 TRPS1 AMOTL2 DDX3X	3.06e-06	925	72	11	28986522
Pubmed	SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.	NEDD4L RIMS1 RIMS2	3.80e-06	15	72	3	23999003
Pubmed	ZC3H13 reduced DUOX1-mediated ferroptosis in laryngeal squamous cell carcinoma cells through m6A-dependent modification.	DUOX1 ZC3H13	4.23e-06	2	72	2	37536262
Pubmed	RIM genes differentially contribute to organizing presynaptic release sites.	RIMS1 RIMS2	4.23e-06	2	72	2	22753485
Pubmed	A presynaptic phosphosignaling hub for lasting homeostatic plasticity.	RIMS1 RIMS2	4.23e-06	2	72	2	35443170
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	4.23e-06	2	72	2	11448776
Pubmed	Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.	RIMS1 RIMS2	4.23e-06	2	72	2	28701482
Pubmed	RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction.	RIMS1 RIMS2	4.23e-06	2	72	2	25240052
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	4.23e-06	2	72	2	16041389
Pubmed	RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.	RIMS1 RIMS2	4.23e-06	2	72	2	29606581
Pubmed	Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage.	SPTBN1 SPTBN2	4.23e-06	2	72	2	26884715
Pubmed	RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.	RIMS1 RIMS2	4.23e-06	2	72	2	26400943
Pubmed	The presynaptic active zone protein RIM1α controls epileptogenesis following status epilepticus.	RIMS1 RIMS2	4.23e-06	2	72	2	22956829
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN5 SPTBN1 SPTBN2	6.79e-06	18	72	3	12119179
Pubmed	A human MAP kinase interactome.	TPR ZNF142 NEDD4L SPTBN1 SPTBN2 KIF5A CCDC88B NSD3	7.51e-06	486	72	8	20936779
Pubmed	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.	USP42 CHD1 AMOTL2 DNTTIP2	1.24e-05	68	72	4	22779921
Pubmed	RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse.	RIMS1 RIMS2	1.27e-05	3	72	2	25343783
Pubmed	RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction.	RIMS1 RIMS2	1.27e-05	3	72	2	21241895
Pubmed	Identification and characterization of a novel tight junction-associated family of proteins that interacts with a WW domain of MAGI-1.	AMOTL1 AMOTL2	1.27e-05	3	72	2	16019084
Pubmed	Sensory-related neural activity regulates the structure of vascular networks in the cerebral cortex.	RIMS1 RIMS2	1.27e-05	3	72	2	25155955
Pubmed	RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain.	RIMS1 RIMS2	1.27e-05	3	72	2	31486769
Pubmed	RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone.	RIMS1 RIMS2	1.27e-05	3	72	2	21262468
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	1.27e-05	3	72	2	25637021
Pubmed	YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.	NEDD4L AMOTL1	1.27e-05	3	72	2	22558212
Pubmed	Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains.	AMOTL1 AMOTL2	1.27e-05	3	72	2	12406577
Pubmed	Differential expression of the motin family in the peri-implantation mouse uterus and their hormonal regulation.	AMOTL1 AMOTL2	1.27e-05	3	72	2	22813598
Pubmed	Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis.	RIMS1 RIMS2	1.27e-05	3	72	2	25730884
Pubmed	Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.	RIMS1 RIMS2	1.27e-05	3	72	2	26034270
Pubmed	Alternative splicing in the first alpha-helical region of the Rab-binding domain of Rim regulates Rab3A binding activity: is Rim a Rab3 effector protein during evolution?	RIMS1 RIMS2	1.27e-05	3	72	2	15330860
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SNIP1 SNW1 ZC3H13 CWC22 CPSF7 NCOA5	1.40e-05	251	72	6	31076518
Pubmed	Mammalian SP/KLF transcription factors: bring in the family.	SP8 SP3 SP7	1.89e-05	25	72	3	15820306
Pubmed	Protein composition of axonal dopamine release sites in the striatum.	RIMS1 RIMS2	2.53e-05	4	72	2	36579890
Pubmed	Control of Fiat (factor inhibiting ATF4-mediated transcription) expression by Sp family transcription factors in osteoblasts.	SP3 SP7	2.53e-05	4	72	2	23463631
Pubmed	The endothelial E3 ligase HECW2 promotes endothelial cell junctions by increasing AMOTL1 protein stability via K63-linked ubiquitination.	AMOTL1 AMOTL2	2.53e-05	4	72	2	27498087
Pubmed	Divergent properties and independent regulation of striatal dopamine and GABA co-transmission.	RIMS1 RIMS2	2.53e-05	4	72	2	35584679
Pubmed	Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels.	RIMS1 RIMS2	2.53e-05	4	72	2	20452978
Pubmed	Angiomotin regulates endothelial cell migration during embryonic angiogenesis.	AMOTL1 AMOTL2	2.53e-05	4	72	2	17699752
Pubmed	Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.	RASA4 RASA4B	2.53e-05	4	72	2	21460216
Pubmed	RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13.	RIMS1 RIMS2	2.53e-05	4	72	2	21262469
Pubmed	Angiomotin'g YAP into the nucleus for cell proliferation and cancer development.	AMOTL1 AMOTL2	2.53e-05	4	72	2	24003252
Pubmed	Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.	RIMS1 RIMS2	2.53e-05	4	72	2	12620390
Pubmed	Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.	RASA4 RASA4B	2.53e-05	4	72	2	16234249
Pubmed	Angiomotin-like proteins associate with and negatively regulate YAP1.	AMOTL1 AMOTL2	2.53e-05	4	72	2	21187284
Pubmed	Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.	SPTBN1 SPTBN2	2.53e-05	4	72	2	24064296
Pubmed	Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking.	RIMS1 RIMS2	2.53e-05	4	72	2	27537483
Pubmed	Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.	SPTBN1 SPTBN2	2.53e-05	4	72	2	21412925
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SNW1 ZC3H13 SPTBN1 CWC22 DDX3X	2.75e-05	169	72	5	23084401
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	SNW1 SPTBN1 RBM23 DDX3X NCOA5	2.82e-05	170	72	5	16159877
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A TPR SNW1 NEDD4L SPTBN1 IQSEC2 SPTBN2 KIF5A RIMS1 DDX3X	2.87e-05	963	72	10	28671696
Pubmed	OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.	AMOTL1 CHD1 AMOTL2 CPSF7	3.94e-05	91	72	4	30472188
Pubmed	RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.	RIMS1 RIMS2	4.21e-05	5	72	2	22248876
Pubmed	Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex.	RIMS1 RIMS2	4.21e-05	5	72	2	37770450
Pubmed	Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex.	RIMS1 RIMS2	4.21e-05	5	72	2	22553025
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	RIMS1 RIMS2	4.21e-05	5	72	2	34706221
Pubmed	Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.	RIMS1 RIMS2	4.21e-05	5	72	2	33139401
Pubmed	Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus.	RIMS1 RIMS2	4.21e-05	5	72	2	12871946
Pubmed	Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.	AMOTL1 AMOTL2	4.21e-05	5	72	2	21205866
Pubmed	Trps1 transcription factor regulates mineralization of dental tissues and proliferation of tooth organ cells.	TRPS1 SP7	4.21e-05	5	72	2	30691926
Pubmed	RIM1/2 in retinal ganglion cells are required for the refinement of ipsilateral axons and eye-specific segregation.	RIMS1 RIMS2	4.21e-05	5	72	2	28607399
Pubmed	Regulation of cyclin D1 RNA stability by SNIP1.	SNIP1 SNW1	4.21e-05	5	72	2	18794151
Pubmed	A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.	RIMS1 RIMS2	4.21e-05	5	72	2	32755572
Pubmed	TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.	SPTBN1 SPTBN2	4.21e-05	5	72	2	26784546
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	SMG1 SPATA6L HAUS1 RNASEH2C KIF19 KIF5A STX11 DNTTIP2 ZNF646	5.44e-05	832	72	9	36724073
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN CWC22 ANO8 NCOA5	5.92e-05	101	72	4	10997877
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	TPR SNW1 ZC3H13 CHD1 DNTTIP2 DDX3X NSD3 CPSF7 NCOA5	6.24e-05	847	72	9	35850772
Pubmed	ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.	SPTBN1 SPTBN2	6.31e-05	6	72	2	37069398
Pubmed	Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.	AMOTL1 AMOTL2	6.31e-05	6	72	2	17397395
Pubmed	The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators.	RIMS1 RIMS2	6.31e-05	6	72	2	31679900
Pubmed	How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.	RIMS1 RIMS2	6.31e-05	6	72	2	27537484
Pubmed	cAMP-GEFII is a direct target of cAMP in regulated exocytosis.	RIMS1 RIMS2	6.31e-05	6	72	2	11056535
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SNIP1 SNW1 USP42 FBXO28 ZC3H13 NFRKB DNTTIP2 DDX3X NSD3 CPSF7 NCOA5	6.83e-05	1294	72	11	30804502
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TPR SMG1 SNW1 NEDD4L SPTBN2 DDX3X CPSF7	7.81e-05	498	72	7	36634849
Pubmed	Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.	RIMS1 RIMS2	8.82e-05	7	72	2	29398114
Pubmed	Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.	RIMS1 RIMS2	8.82e-05	7	72	2	36398873
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 ST6GAL2 AMOTL2 RIMS2 DNMBP CWC22 ZNF646	1.14e-04	529	72	7	14621295
Pubmed	Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.	RASA4 RASA4B	1.17e-04	8	72	2	10810084
Pubmed	CFIm-mediated alternative polyadenylation safeguards the development of mammalian pre-implantation embryos.	SMG1 CPSF7	1.17e-04	8	72	2	36563685
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	TPR SNW1 ZC3H13 KCTD10 SPTBN1 AMOTL1 AMOTL2 DDX3X CPSF7	1.19e-04	922	72	9	27609421
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TPR SNW1 SPTBN2 AMOTL1 NFRKB AMOTL2 NSD3	1.43e-04	549	72	7	38280479
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	TPR SNW1 ZC3H13 SPTBN1 SPTBN2 DDX3X CPSF7	1.46e-04	551	72	7	34728620
Pubmed	Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning.	SP8 SP7	1.51e-04	9	72	2	17509151
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1I	1.51e-04	9	72	2	16382099
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SNIP1 RSBN1 ZNF142 USP42 SPTBN1 IQSEC2 CHD1 DNTTIP2 CPSF7 ZNF646	1.81e-04	1203	72	10	29180619
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	SPTBN1 SPTBN2	1.88e-04	10	72	2	22159418
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ZNF131 ST6GAL2 ADAMTS2 FBXO28 ZC3H13 OBSCN CHD1 FUT1 RIMS2 NCOA5	1.96e-04	1215	72	10	15146197
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SMG1 ZNF131 SNW1 DNMBP CWC22 DNTTIP2	2.10e-04	410	72	6	26949251
Pubmed	Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.	AMOTL1 AMOTL2	2.30e-04	11	72	2	28239148
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTBN1 SPTBN2	2.30e-04	11	72	2	17607528
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	RIMS1 RIMS2	2.30e-04	11	72	2	34767769
Pubmed	Identification of Osr2 Transcriptional Target Genes in Palate Development.	SEMA3D SP7	2.30e-04	11	72	2	28731788
Pubmed	Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.	SPTBN1 DDX3X	2.30e-04	11	72	2	39256359
Interaction	SNRNP40 interactions	SNIP1 RSBN1 ZNF131 SNW1 USP42 ZC3H13 NFRKB CHD1 CWC22 DNTTIP2 NSD3 CPSF7 NCOA5	2.52e-07	637	70	13	int:SNRNP40
Interaction	IFI27L1 interactions	SNIP1 SNW1 ZC3H13 DNTTIP2 NCOA5	3.07e-06	65	70	5	int:IFI27L1
Interaction	TNIK interactions	CACNA1A TPR NEDD4L SPTBN1 IQSEC2 SPTBN2 KIF5A RIMS1 DDX3X	6.60e-06	381	70	9	int:TNIK
Interaction	SLC26A1 interactions	ST6GAL2 SRGAP1 SLC26A1	8.63e-06	12	70	3	int:SLC26A1
Interaction	LINC02910 interactions	SNIP1 ZC3H13 RBM23 DNTTIP2 NCOA5	1.99e-05	95	70	5	int:LINC02910
Interaction	YAP1 interactions	TPR TGM1 SNW1 NEDD4L SPTBN1 SPTBN2 AMOTL1 NFRKB CHD1 KIF5A AMOTL2 DDX3X NSD3 CPSF7	2.00e-05	1095	70	14	int:YAP1
Interaction	KALRN interactions	CACNA1A KCTD10 SPTBN1 IQSEC2 SPTBN2	2.09e-05	96	70	5	int:KALRN
Interaction	YWHAH interactions	NEDD4L CEP85L SRGAP1 ZC3H13 SPTBN1 IQSEC2 KIF5A RIMS1 AMOTL2 RIMS2 DNMBP CWC22 DDX3X NSD3	2.14e-05	1102	70	14	int:YWHAH
Interaction	RAD18 interactions	SNIP1 SNW1 SRGAP1 ZC3H13 SPTBN1 CHD1 CWC22 CPSF7 NCOA5	2.80e-05	457	70	9	int:RAD18
Interaction	MAGOH interactions	SNIP1 SMG1 SNW1 ZC3H13 SPTBN1 DDX3X CPSF7	3.63e-05	264	70	7	int:MAGOH
Interaction	ANAPC15 interactions	SNIP1 SNW1 ZC3H13 DNTTIP2 NCOA5	8.31e-05	128	70	5	int:ANAPC15
Interaction	CLP1 interactions	SNW1 TSEN54 CPSF7 SP7	8.67e-05	67	70	4	int:CLP1
Interaction	APEX1 interactions	RSBN1 ZNF131 TGM1 FAM193A MZF1 CEP85L SPTBN1 IQSEC2 SPTBN2 TRPS1 AMOTL2 DNTTIP2 DDX3X NSD3	1.01e-04	1271	70	14	int:APEX1
Interaction	SMC5 interactions	TPR RSBN1 ZNF131 SNW1 ZC3H13 NFRKB CHD1 CWC22 DNTTIP2 DDX3X NSD3 CPSF7	1.55e-04	1000	70	12	int:SMC5
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTBN1 SPTBN2	6.50e-07	7	49	3	1113
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP8 SP3 SP7	1.55e-06	9	49	3	755
GeneFamily	Regulating synaptic membrane exocytosis family\|PDZ domain containing	RIMS1 RIMS2	4.30e-05	4	49	2	833
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	3.19e-04	10	49	2	830
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP8 ZNF131 SP3 ZNF142 MZF1 TRPS1 SP7 ZNF646	6.34e-04	718	49	8	28
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1I	2.24e-03	26	49	2	253
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SBF2 SPTBN1 SPTBN2 RASA4B	2.32e-03	206	49	4	682
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF19 KIF5A	6.90e-03	46	49	2	622
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL	CACNA1A RTL5 RASA4 SRGAP1 SPTBN2 KIF19 RASA4B RIMS2 SEZ6L2 ZNF646	2.70e-07	429	72	10	M45694
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_PULMONARY_NE_PRECURSOR_CELL	CACNA1A RASA4 SRGAP1 SPTBN2 KIF19 RASA4B RIMS2 SEZ6L2	1.88e-06	304	72	8	M45711
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL	CACNA1A RASA4 SPTBN2 KIF19 RASA4B RIMS2 SEZ6L2	9.03e-06	268	72	7	M45696
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_PULMONARY_NEUROENDOCRINE_CELL	CACNA1A SRGAP1 KIF19 RASA4B RIMS2 SEZ6L2	4.43e-05	233	72	6	M45712
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	CACNA1A ST6GAL2 NEDD4L CEP85L RASA4 SRGAP1 SBF2 CACNA1I RIMS1 RIMS2 SEZ6L2 ANO8	4.44e-05	1106	72	12	M39071
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	TPR SMG1 SEMA3D FAM193A SRGAP1 TRPS1 NSD3 ZNF646	9.46e-06	312	71	8	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000	SEMA3D ZNF142 GPC3 ADAMTS2 SPTBN1 AMOTL1 TRPS1	2.35e-05	256	71	7	gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	TPR RSBN1 SEMA3D FAM193A SRGAP1 TRPS1 CHD1 DNMBP	3.16e-05	369	71	8	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	TPR SMG1 RSBN1 FAM193A TRPS1 CHD1 DNMBP ZNF646	4.27e-05	385	71	8	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	SP3 ADAMTS2 ZC3H13 SPTBN1	6.66e-05	65	71	4	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	SMG1 SP3 SEMA3D ZNF142 GPC3 ADAMTS2 ZC3H13 SPTBN1 AMOTL1 TRPS1 NSD3	6.66e-05	801	71	11	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	TPR RSBN1 SP8 ST6GAL2 SP3 SEMA3D FAM193A SRGAP1 TRPS1 CHD1 DNMBP	7.04e-05	806	71	11	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	TPR SMG1 RSBN1 SP8 FAM193A TRPS1 CHD1 KIF5A DNMBP SEZ6L2 ZNF646	8.04e-05	818	71	11	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05	RSBN1 SEMA3D ADAMTS2 MZF1 RTL5 METRNL RASA4 NFRKB OBSCN RASA4B ANO8 BAHCC1 NCOA5	2.19e-04	1245	71	13	PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	RSBN1 SP8 TGM1 ST6GAL2 SEMA3D FAM193A TRPS1 CHD1 RIMS1 RIMS2	2.29e-04	769	71	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	SMG1 SP3 SEMA3D ZNF142 GPC3 ADAMTS2 ZC3H13 SPTBN1 TRPS1 NSD3	2.84e-04	790	71	10	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	TPR RSBN1 SP8 ST6GAL2 FAM193A NEDD4L USP42 CEP85L ZC3H13 TRPS1 CHD1 CWC22 DNTTIP2 DDX3X	2.91e-04	1459	71	14	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	TPR SMG1 SP8 SEMA3D FAM193A NEDD4L SRGAP1 TRPS1 NSD3 ZNF646	3.33e-04	806	71	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000	SMG1 SEMA3D ZC3H13 SPTBN1 TRPS1 NSD3	3.55e-04	281	71	6	gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	CACNA1A SP8 SEMA3D NEDD4L ADAMTS2 TRPS1 CHD1 RIMS2 CWC22 DNTTIP2 DDX3X	3.97e-04	983	71	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	CACNA1A ST6GAL2 NEDD4L CHD1 RIMS2 DDX3X	4.84e-04	298	71	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 SP3 GPC3 SPTBN1 TRPS1 DDX3X	8.51e-07	199	72	6	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A SPTBN2 RIMS1 RIMS2 SEZ6L2	5.98e-06	159	72	5	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TGM1 NEDD4L SPTBN2 RIMS1 SEZ6L2	7.82e-06	168	72	5	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TGM1 NEDD4L SPTBN2 RIMS1 SEZ6L2	7.82e-06	168	72	5	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A USP42 RTL5 RASA4 KIF5A	9.27e-06	174	72	5	ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SMG1 SPTBN1 TRPS1 CHD1	1.15e-05	182	72	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SMG1 SPTBN1 CHD1 DDX3X	1.21e-05	184	72	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SMG1 SPTBN1 TRPS1 CHD1	1.25e-05	185	72	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TPR SMG1 SP3 FBXO28 ZC3H13	1.28e-05	186	72	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	SMG1 METRNL CHD1 DDX3X NSD3	1.53e-05	193	72	5	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ST6GAL2 SEMA3D GPC3 SBF2 SPTBN1	1.61e-05	195	72	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SMG1 METRNL CHD1 DDX3X NSD3	1.69e-05	197	72	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 GPC3 SPTBN1 TRPS1 DDX3X	1.73e-05	198	72	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMG1 METRNL CHD1 DDX3X NSD3	1.73e-05	198	72	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 GPC3 SPTBN1 TRPS1 DDX3X	1.73e-05	198	72	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMG1 METRNL CHD1 DDX3X NSD3	1.73e-05	198	72	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 SP3 GPC3 TRPS1 DDX3X	1.73e-05	198	72	5	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	IQSEC2 C1orf167 RIMS2 SP7	7.84e-05	140	72	4	82b150e9e9962460a5cd6bef7ee04f28f5c05d1a
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	IQSEC2 C1orf167 RIMS2 SP7	9.98e-05	149	72	4	649eb3441fa859591ea85f1ed5fcf08af272a32b
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	SPTBN1 C1orf167 ANO8 NCOA5	1.13e-04	154	72	4	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TGM1 USP42 TRPS1 NCOA5	1.28e-04	159	72	4	ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TGM1 USP42 TRPS1 NCOA5	1.28e-04	159	72	4	2f6c60ddff2208a68146f9786143d9aefd528840
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D GPC3 ADAMTS2 SP7	1.28e-04	159	72	4	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 SEMA3D RIMS1 RIMS2	1.31e-04	160	72	4	8624f101828efd32cdd38a65df8d94d690720a63
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 SEMA3D RIMS1 RIMS2	1.31e-04	160	72	4	9de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAUS1 USP42 IQSEC2 CHD1	1.31e-04	160	72	4	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN5 SNIP1 GPC3 FUT1	1.34e-04	161	72	4	0d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell	Mild_COVID-19-Myeloid-MoAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CACNA1A ADAMTS2 RTL5 METRNL	1.38e-04	162	72	4	e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL2 SPATA6L RIMS1 RIMS2	1.38e-04	162	72	4	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A KIF5A RIMS1 RIMS2	1.44e-04	164	72	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	TGM1 SPTBN2 RIMS1 SEZ6L2	1.51e-04	166	72	4	4d63c758d46e73311b864148c646bf081498dee7
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	TGM1 SPTBN2 RIMS1 SEZ6L2	1.51e-04	166	72	4	4160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A KIF19 RIMS2 SEZ6L2	1.51e-04	166	72	4	afba41e15478053f11815acf568d29187de75492
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A MZF1 DNMBP CCDC88B	1.55e-04	167	72	4	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP42 SPTBN1 KIF5A RBM23	1.55e-04	167	72	4	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A KIF5A RIMS1 RIMS2	1.62e-04	169	72	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPTBN2 KIF5A RIMS2 SEZ6L2	1.85e-04	175	72	4	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOX1 NEDD4L CWC22 BAHCC1	1.85e-04	175	72	4	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPTBN2 KIF5A RIMS2 SEZ6L2	1.85e-04	175	72	4	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN2 KIF19 SEZ6L2 ZNF646	1.85e-04	175	72	4	24651f95540ea2c8f3720aa943cbdd15661ee3fa
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RFPL4B METRNL SRGAP1 TRPS1	1.93e-04	177	72	4	4f88ea4cfcfa8a9af5a14ab6f6be3b2aa015852e
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ST6GAL2 KIF5A RIMS1 RIMS2	2.02e-04	179	72	4	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CACNA1A KIF5A RIMS2 SEZ6L2	2.06e-04	180	72	4	57689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DUOX1 NEDD4L SPTBN1 C1orf167	2.06e-04	180	72	4	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A SPTBN2 RIMS2 SEZ6L2	2.11e-04	181	72	4	cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASA4 KIF5A RIMS1 RIMS2	2.15e-04	182	72	4	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL2 SPATA6L RIMS1 RIMS2	2.15e-04	182	72	4	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1A RTL5 SPTBN2 SEZ6L2	2.15e-04	182	72	4	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1A RTL5 SPTBN2 SEZ6L2	2.15e-04	182	72	4	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPATA6L ADAMTS2 ANO8 BAHCC1	2.24e-04	184	72	4	d754c3de621429b220ae4ac426cdfc619e848462
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A KIF19 RIMS2 SEZ6L2	2.24e-04	184	72	4	1e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS2 METRNL TRPS1 DNTTIP2	2.24e-04	184	72	4	d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC3 ADAMTS2 METRNL SRGAP1	2.29e-04	185	72	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC3 ADAMTS2 METRNL SRGAP1	2.29e-04	185	72	4	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC3 ADAMTS2 METRNL SRGAP1	2.29e-04	185	72	4	a94694e226856bc5b168464f52d76004145717a5
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A RTL5 RIMS2 SEZ6L2	2.29e-04	185	72	4	2a8104f610fa5ce618f8105521616722462a0d42
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 KIF5A RIMS1 RIMS2	2.34e-04	186	72	4	a1ab273b01971d6a892912560d387685dd657179
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ZNF131 CHD1 NSD3	2.38e-04	187	72	4	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 KIF5A RIMS1 RIMS2	2.38e-04	187	72	4	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D ADAMTS2 METRNL SPTBN1	2.38e-04	187	72	4	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1I KIF5A RIMS1 RIMS2	2.38e-04	187	72	4	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZC3H13 AMOTL2 DNMBP NCOA5	2.43e-04	188	72	4	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D GPC3 ADAMTS2 DDX3X	2.43e-04	188	72	4	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 CEP85L CHD1 DDX3X	2.43e-04	188	72	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SPTBN1 AMOTL1 AMOTL2	2.43e-04	188	72	4	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 KIF5A RIMS1 RIMS2	2.48e-04	189	72	4	3d838da870623a6a278ddc8e6cedca85d9877e50
ToppCell	18-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	CACNA1A KIF5A RIMS2 SEZ6L2	2.48e-04	189	72	4	144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SPTBN1 AMOTL1 AMOTL2	2.53e-04	190	72	4	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS2 SPTBN1 AMOTL1 DDX3X	2.53e-04	190	72	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SPTBN1 AMOTL1 AMOTL2	2.53e-04	190	72	4	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	SEMA3D GPC3 ADAMTS2 SPTBN1	2.53e-04	190	72	4	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS2 SRGAP1 TRPS1 DNMBP	2.53e-04	190	72	4	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1A KIF19 RASA4B RIMS2	2.53e-04	190	72	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ST6GAL2 SEMA3D GPC3 ADAMTS2	2.53e-04	190	72	4	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF19 KIF5A RIMS1 RIMS2	2.64e-04	192	72	4	4d3a1c267739b1479217144656986972fc86db43
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A KIF19 RIMS2 SEZ6L2	2.64e-04	192	72	4	5692bd57093852d442400383850f416c497dcc7d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA3D GPC3 ADAMTS2 SRGAP1	2.69e-04	193	72	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP1 SPTBN1 AMOTL1 AMOTL2	2.69e-04	193	72	4	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP1 SPTBN1 AMOTL1 AMOTL2	2.69e-04	193	72	4	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	COPD-Myeloid-ncMonocyte\|COPD / Disease state, Lineage and Cell class	SRGAP1 SBF2 CHD1 DNMBP	2.69e-04	193	72	4	936ca95995599356b794fba32bfd82d8de339365
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A RASA4 SPTBN2 RIMS1	2.69e-04	193	72	4	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP1 SPTBN1 AMOTL1 AMOTL2	2.69e-04	193	72	4	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA3D GPC3 ADAMTS2 SRGAP1	2.74e-04	194	72	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CEP85L CHD1 NSD3	2.74e-04	194	72	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1A KIF19 RASA4B SEZ6L2	2.74e-04	194	72	4	ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ST6GAL2 SEMA3D GPC3 SPTBN1	2.74e-04	194	72	4	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SP8 NEDD4L RIMS1 RIMS2	2.80e-04	195	72	4	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ST6GAL2 NEDD4L RIMS1 RIMS2	2.80e-04	195	72	4	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L SPTBN1 C1orf167 AMOTL2	2.85e-04	196	72	4	eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA3D GPC3 ADAMTS2 SBF2	2.85e-04	196	72	4	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	METRNL TRPS1 CHD1 DNTTIP2	2.85e-04	196	72	4	01cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	NEDD4L GPC3 SPTBN2 RIMS1	2.91e-04	197	72	4	2701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NEDD4L GPC3 SPTBN2 RIMS1	2.91e-04	197	72	4	751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOX1 NEDD4L SPTBN1 C1orf167	2.91e-04	197	72	4	c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA3D GPC3 SBF2 SPTBN1	2.91e-04	197	72	4	31a1852911bda38543916585fda34255fd62a134
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOX1 NEDD4L SPTBN1 C1orf167	2.91e-04	197	72	4	e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA3D GPC3 SBF2 SPTBN1	2.91e-04	197	72	4	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NEDD4L GPC3 SPTBN2 RIMS1	2.91e-04	197	72	4	58d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOX1 NEDD4L SPTBN1 C1orf167	2.91e-04	197	72	4	734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGM1 GPC3 AMOTL2 SEZ6L2	2.96e-04	198	72	4	5cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
Drug	ADPribulose	SPTBN5 SPTBN1 SPTBN2	7.79e-06	13	70	3	CID000197570
Drug	PRODAN	SPTBN5 SPTBN1 SPTBN2	1.23e-05	15	70	3	CID000028127
Drug	6-propionyl-2-(dimethylamino)naphthalene	SPTBN5 SPTBN1 SPTBN2	1.51e-05	16	70	3	CID000107729
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN1 SPTBN2	3.22e-05	4	69	2	DOID:0050882 (implicated_via_orthology)
Disease	alcohol consumption measurement	SPTBN5 CACNA1A SP8 ST6GAL2 SPTBN1 TRPS1 CACNA1I RIMS2 SEZ6L2 BAHCC1	5.98e-04	1242	69	10	EFO_0007878
Disease	Tourette syndrome, schizophrenia	CACNA1I NSD3	8.05e-04	18	69	2	EFO_0004895, MONDO_0005090
Disease	Dystonia	CACNA1A ZNF142 RNASEH2C	1.09e-03	86	69	3	C0013421
Disease	Neurodevelopmental Disorders	IQSEC2 RIMS1 DDX3X	1.37e-03	93	69	3	C1535926
Disease	albuminuria	SBF2 FUT1 BAHCC1	1.41e-03	94	69	3	EFO_0004285
Disease	ergothioneine measurement	CACNA1A RIMS2	1.69e-03	26	69	2	EFO_0021163
Disease	RS-10-hydroxywarfarin to RS-warfarin ratio measurement	SPATA6L NEDD4L CEP85L	2.21e-03	110	69	3	EFO_0803335
Disease	Epileptic encephalopathy	CACNA1A NEDD4L	2.25e-03	30	69	2	C0543888

Protein segments in the cluster

Peptide	Gene	Start	Entry
EENQRHHQRRRDRSH	CACNA1A	2146	O00555
RRQDEALRELRHGHV	AMOTL2	141	Q9Y2J4
RSHHLDEDEERERIE	KCTD10	281	Q9H3F6
ARLQRKHDHERDESS	BAHCC1	1461	Q9P281
RVHREEERTAFHLSD	C1orf167	471	Q5SNV9
ERSLESRDHLHREQR	CCDC88B	1261	A6NC98
AVRTASEDHRRHIEI	AMOTL1	566	Q8IY63
ERGHRDLEQFERVHR	DNMBP	1071	Q6XZF7
KLDDHRSRDHRSNLE	CHD1	1606	O14646
AREHLHLQEEQRRRE	FAM193A	891	P78312
LEEHANSSRRRARRH	ADAMTS2	246	O95450
EEEERQRHAEHHARR	ANO8	906	Q9HCE9
HLRERHADARTSRTL	RASA4	486	O43374
SESRSRDHRREDRVH	RBM23	111	Q86U06
HLRERHADARTSRTL	RASA4B	486	C9J798
SRESSRRHRDLLHNE	CPSF7	431	Q8N684
RRHRDLLHNEDRHDD	CPSF7	436	Q8N684
TREQRRHLLETFFRH	DUOX1	756	Q9NRD9
IHGDRSQRDREEALH	DDX3X	471	O00571
HRDRSEEEFERIHQA	NFRKB	651	Q6P4R8
HIETLEAVHRESRRL	SBF2	851	Q86WG5
AHVEHEETLSSRRRE	GPC3	376	P51654
LREESQLHRGELHRD	IQSEC2	61	Q5JU85
ERRQEHGHQETRTER	CWC22	746	Q9HCG8
HGHQETRTERERRSE	CWC22	751	Q9HCG8
SRDIRDPRDLRDHRH	NCOA5	51	Q9HCD5
DPRDLRDHRHSRDLR	NCOA5	56	Q9HCD5
ELVRRHRASDLHELS	METRNL	171	Q641Q3
EQSLHVREELRHFRE	RFPL4B	81	Q6ZWI9
VSRARHERRHSDVAL	RIMS1	381	Q86UR5
RHRHEAVRRLEQHRS	KIF19	591	Q2TAC6
HETLRDGDRHSLRQD	OBSCN	3661	Q5VST9
SRARHERRHSDVSLA	RIMS2	391	Q9UQ26
QREQLHREHEDTRDL	CCDC166	251	P0CW27
RHHRRTLSLDNRDSV	CACNA1I	1051	Q9P0X4
ELSNRLVDLERRSHH	CPTP	86	Q5TA50
RRESERRNHSLARHA	FBXO28	126	Q9NVF7
THLHERIRDNELRAQ	CEP85L	386	Q5SZL2
HREAHHRQLARLRDE	KIF5A	706	Q12840
HARHLQNEDIRVRRS	FAM240C	36	A0A1B0GVR7
IRREFTLHDHLREEA	FUT1	181	P19526
EDEDQEARRHRLHSK	RTL5	346	Q5HYW3
REVLFEDRTRAHADH	RSBN1	571	Q5VWQ0
FLHRNRFLEERHESR	SPATA6L	136	Q8N4H0
DRQHREPSEQEHRRA	SNIP1	121	Q8TAD8
EHRRARNSDRDRHRG	SNIP1	131	Q8TAD8
FHIRLEERHQRRSSV	SRGAP1	201	Q7Z6B7
EKLSRREREHHAEAA	TSEN54	346	Q7Z6J9
ILHHLSERNRVRDRD	HAUS1	36	Q96CS2
VSRQRHDDTRVHADI	SMG1	66	Q96Q15
RHRRQRRSHVLEEGD	ST6GAL2	176	Q96JF0
RRLHLHFERVSLDED	SEZ6L2	386	Q6UXD5
HALRDTETTLRVHRD	SPTBN5	1831	Q9NRC6
RFTRSDELQRHLRTH	SP8	396	Q8IXZ3
NRRHHRDLDELPRAV	SEMA3D	761	O95025
TEKRHRRLEEAHRAQ	SPTBN1	1581	Q01082
VSEHHDTILRVTRRR	DNTTIP2	96	Q5QJE6
ERRSEDHLTESHQRE	TRPS1	981	Q9UHF7
SFRLIRDLHQHLRER	TMEM199	56	Q8N511
DKHRDRDSRHQQDSD	USP42	1206	Q9H9J4
ARQHRALEEEIRSHR	SPTBN2	786	O15020
HDAVQTARARHRELE	SLC26A1	681	Q9H2B4
TARARHRELEATDAH	SLC26A1	686	Q9H2B4
TRSDELERHVRTHTR	SP7	336	Q8TDD2
SRLERELREHQERHL	TPR	1611	P12270
HRELLRLESRIRDVH	STX11	211	O75558
RFTRSDELQRHRRTH	SP3	661	Q02447
RGSLERHLREHEETE	ZNF646	1376	O15015
EAAIERHRVHLRSAT	RNASEH2C	6	Q8TDP1
RHDRRKERQHDRNLS	SNW1	356	Q13573
EIRRHSQRRHTSAEE	NSD3	446	Q9BZ95
DLLSSRSDQNRREHH	TGM1	116	P22735
RRHLSDAHNISERLV	ZNF131	436	P52739
LRVHQETRHREARAF	ZNF142	1551	P52746
TSQSHDRRHERREDT	ZC3H13	406	Q5T200
FVRSARLEEHRRVHT	MZF1	421	P28698
HRRFRSRRHISEDLE	NEDD4L	246	Q96PU5