Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2B KMT2C KMT2D	2.75e-05	8	160	3	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2B KMT2C KMT2D	5.81e-05	10	160	3	GO:0140999
GeneOntologyMolecularFunction	chromatin binding	FOXO1 POLR1A EP400 CHD8 CHD7 SMARCAD1 ONECUT1 CREBBP HDAC7 PHC2 JARID2 ATXN7 TP63 TLE4 SKOR2 CUX1 HR	9.41e-05	739	160	17	GO:0003682
GeneOntologyMolecularFunction	polyamine oxidase activity	PAOX IL4I1	1.90e-04	3	160	2	GO:0046592
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	EP400 CHD8 CHD7 SMARCAD1	2.13e-04	37	160	4	GO:0140658
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor	PAOX IL4I1	3.79e-04	4	160	2	GO:0016647
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2B JARID2 KMT2C KMT2D	4.20e-04	44	160	4	GO:0140938
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2B KMT2C KMT2D	5.21e-04	20	160	3	GO:0042800
GeneOntologyCellularComponent	nuclear protein-containing complex	RANGAP1 KMT2B POLR1A WWOX AFF2 EP400 NUP210L BICRA CHD8 MIDEAS ADAR CREBBP HDAC7 PHC2 EFTUD2 PCF11 JARID2 KMT2C KMT2D R3HCC1L ATXN7 TLE4 CPSF1 BICRAL SAP130 HR	1.52e-05	1377	159	26	GO:0140513
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2B CHD8 JARID2 KMT2C KMT2D	2.69e-04	75	159	5	GO:0035097
GeneOntologyCellularComponent	nuclear speck	AFF2 EP400 ADAMTS4 BMP2K RADX SRY UBASH3A ADAR EFTUD2 SAP130 MAML3	4.75e-04	431	159	11	GO:0016607
GeneOntologyCellularComponent	histone deacetylase complex	EP400 MIDEAS HDAC7 SAP130 HR	4.80e-04	85	159	5	GO:0000118
HumanPheno	Bilateral choanal atresia	FAT4 POLR1A KMT2D TP63 DCHS1	3.51e-08	9	65	5	HP:0004502
HumanPheno	Abnormal earlobe morphology	HIVEP2 KMT2B WWOX BICRA CHD7 CREBBP EFTUD2 KMT2C KMT2D SEC24C FGD1 PHIP	1.05e-07	137	65	12	HP:0000363
HumanPheno	Epicanthus	HSPG2 FAT4 KMT2B POLR1A WWOX AFF2 ANK1 BICRA CHD8 SRY CHD7 RFX7 CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C DCHS1 FGD1 FGFR3 CTNND2 GDF11 PHIP	1.84e-07	614	65	24	HP:0000286
HumanPheno	Abnormality of the outer ear	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX AFF2 ANK1 BICRA GRB10 ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ADAR CREBBP PREPL EFTUD2 JARID2 KMT2C KMT2D SEC24C CLCNKA TP63 DCHS1 FGD1 CC2D2A FGFR3 PLEC CTNND2 GDF11 PHIP CUX1	5.14e-07	1337	65	36	HP:0000356
HumanPheno	Microtia	HSPG2 FAT4 HIVEP2 POLR1A CRPPA CHD7 SIM1 EFTUD2 KMT2D TP63 DCHS1 FGFR3 PLEC	7.23e-07	195	65	13	HP:0008551
HumanPheno	Abnormality of the larynx	HSPG2 COL12A1 TRIM2 KMT2B POLR1A WWOX AFF2 LAMA3 GRB10 CRPPA CHD7 SIM1 RFX7 ADAR CREBBP PREPL SIL1 KMT2D SEC24C TP63 FGFR3 PLEC CTNND2 PHIP	8.51e-07	666	65	24	HP:0001600
HumanPheno	Abnormal pinna morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX AFF2 ANK1 BICRA ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ADAR CREBBP PREPL EFTUD2 JARID2 KMT2C KMT2D SEC24C CLCNKA TP63 DCHS1 FGD1 CC2D2A FGFR3 PLEC CTNND2 GDF11 PHIP CUX1	8.68e-07	1299	65	35	HP:0000377
HumanPheno	Aplasia/Hypoplasia of the external ear	HSPG2 FAT4 HIVEP2 POLR1A CRPPA CHD7 SIM1 EFTUD2 KMT2D TP63 DCHS1 FGFR3 PLEC	1.69e-06	210	65	13	HP:0008772
HumanPheno	Abnormal midface morphology	HSPG2 FAT4 KMT2B POLR1A ANK1 BICRA ESAM CHD7 SIM1 RFX7 CREBBP EFTUD2 JARID2 LINS1 KMT2C KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11	2.36e-06	704	65	24	HP:0000309
HumanPheno	Aplasia/Hypoplasia of the ear	HSPG2 FAT4 HIVEP2 POLR1A CRPPA CHD7 SIM1 EFTUD2 KMT2D TP63 DCHS1 FGFR3 PLEC	2.71e-06	219	65	13	HP:0008771
HumanPheno	Abnormality of the jaws	HSPG2 FAT4 COL12A1 KMT2B POLR1A WWOX ANK1 BICRA GRB10 ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ATP10A CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	3.13e-06	1175	65	32	HP:0000209
HumanPheno	Abnormal jaw morphology	HSPG2 FAT4 COL12A1 KMT2B POLR1A WWOX ANK1 BICRA GRB10 ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ATP10A CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	3.20e-06	1176	65	32	HP:0030791
HumanPheno	Abnormal mandible morphology	HSPG2 FAT4 COL12A1 KMT2B POLR1A WWOX ANK1 BICRA GRB10 ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ATP10A CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	3.44e-06	1118	65	31	HP:0000277
HumanPheno	Abnormal calvaria morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA GRB10 TCIRG1 ESAM CRPPA SIM1 RFX7 ADAR CREBBP PREPL PLEKHM1 EFTUD2 PHEX JARID2 KMT2C KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP CUX1 TBX5	4.27e-06	1254	65	33	HP:0002683
HumanPheno	Abnormality of calvarial morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA GRB10 TCIRG1 ESAM CRPPA SIM1 RFX7 ADAR CREBBP PREPL EFTUD2 PHEX JARID2 KMT2C KMT2D SEC24C TP63 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP CUX1 TBX5	4.71e-06	1134	65	31	HP:0002648
HumanPheno	Abnormal thorax morphology	HSPG2 FAT4 COL12A1 HIVEP2 POLR1A WWOX ANK1 BICRA TCIRG1 ESAM CRPPA SRY CHD7 SIM1 RFX7 CREBBP PLEKHM1 SIL1 PHEX KMT2C KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 CUX1 SEC23B GAA TBX5	5.09e-06	1328	65	34	HP:0000765
HumanPheno	Abnormal eyelid morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX AFF2 ANK1 BICRA LAMA3 ESAM CHD8 SRY CHD7 SIM1 RFX7 ADAR CREBBP PREPL EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 DCHS1 FGD1 FGFR3 PLEC CTNND2 GDF11 PHIP CUX1 PCSK9 HR	6.56e-06	1408	65	35	HP:0000492
HumanPheno	Abnormal cheek morphology	HSPG2 FAT4 KMT2B ANK1 BICRA ESAM CHD7 SIM1 CREBBP EFTUD2 KMT2D FGD1 CC2D2A CTNND2	8.69e-06	282	65	14	HP:0004426
HumanPheno	Abnormality of the upper respiratory tract	HSPG2 FAT4 COL12A1 TRIM2 KMT2B POLR1A WWOX AFF2 LAMA3 GRB10 TCIRG1 ESAM CRPPA CHD7 SIM1 RFX7 ADAR CREBBP PREPL SIL1 KMT2C KMT2D SEC24C TP63 DCHS1 FGFR3 PLEC LRBA CTNND2 PHIP	9.90e-06	1111	65	30	HP:0002087
HumanPheno	Syndactyly	FAT4 KMT2B BICRA LAMA3 GRB10 SMARCAD1 RFX7 CREBBP JARID2 TP63 DCHS1 FGD1 FGFR3 PLEC CTNND2 PHIP TBX5	1.13e-05	417	65	17	HP:0001159
HumanPheno	Localized skin lesion	HSPG2 FAT4 COL12A1 POLR1A ANK1 LAMA3 GRB10 TCIRG1 CHD7 SMARCAD1 RFX7 ADAR CREBBP EFTUD2 KMT2D SEC24C TP63 DCHS1 FGD1 FGFR3 PLEC CTNND2 PHIP SEC23B PCSK9 TBX5	1.60e-05	897	65	26	HP:0011355
HumanPheno	Abnormal palate morphology	HSPG2 FAT4 COL12A1 HIVEP2 KMT2B POLR1A ANK1 BICRA GRB10 ESAM CRPPA SRY CHD7 RFX7 CREBBP EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP SEC23B TBX5	1.68e-05	1202	65	31	HP:0000174
HumanPheno	Motor delay	COL12A1 TRIM2 HIVEP2 KMT2B POLR1A WWOX SPTBN2 GRB10 ESAM CRPPA CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP PREPL PHEX LINS1 KMT2C KMT2D CLCNKA ATXN7 TRIM8 FGFR3 PLEC CUX1 GAA	1.71e-05	1018	65	28	HP:0001270
HumanPheno	Micrognathia	HSPG2 FAT4 COL12A1 POLR1A WWOX ANK1 BICRA GRB10 ESAM CHD8 SRY CHD7 SIM1 CREBBP EFTUD2 KMT2D SEC24C DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	1.71e-05	843	65	25	HP:0000347
HumanPheno	Aplasia/Hypoplasia of the mandible	HSPG2 FAT4 COL12A1 POLR1A WWOX ANK1 BICRA GRB10 ESAM CHD8 SRY CHD7 SIM1 CREBBP EFTUD2 KMT2D SEC24C DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	1.78e-05	845	65	25	HP:0009118
HumanPheno	Frontal bossing	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA GRB10 TCIRG1 ESAM CRPPA SIM1 RFX7 CREBBP PREPL PHEX JARID2 KMT2D TP63 FGD1 FGFR3 PHIP CUX1	1.95e-05	738	65	23	HP:0002007
HumanPheno	Abnormal shape of the frontal region	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA GRB10 TCIRG1 ESAM CRPPA SIM1 RFX7 CREBBP PREPL PHEX JARID2 KMT2D TP63 FGD1 FGFR3 PHIP CUX1	2.09e-05	741	65	23	HP:0011218
HumanPheno	Choanal atresia	FAT4 POLR1A CHD7 EFTUD2 KMT2D SEC24C TP63 DCHS1 FGFR3	2.13e-05	123	65	9	HP:0000453
HumanPheno	Abnormal frontal bone morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA GRB10 TCIRG1 ESAM CRPPA SIM1 RFX7 CREBBP PREPL PHEX JARID2 KMT2D TP63 FGD1 FGFR3 PHIP CUX1	2.14e-05	742	65	23	HP:0430000
HumanPheno	Dental malocclusion	HSPG2 FAT4 TCIRG1 CREBBP PLEKHM1 KMT2D TP63 DCHS1 FGD1 FGFR3	2.28e-05	156	65	10	HP:0000689
HumanPheno	Aplasia/Hypoplasia involving bones of the skull	HSPG2 FAT4 COL12A1 POLR1A WWOX ANK1 BICRA GRB10 ESAM CHD8 SRY CHD7 SIM1 CREBBP EFTUD2 KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	2.30e-05	915	65	26	HP:0009116
HumanPheno	Abnormality of the voice	HSPG2 TRIM2 KMT2B POLR1A WWOX AFF2 LAMA3 GRB10 CRPPA CHD7 SIM1 ADAR PREPL SIL1 KMT2D SEC24C TP63 PLEC CTNND2	2.89e-05	545	65	19	HP:0001608
HumanPheno	Tracheomalacia	FAT4 TRIM2 POLR1A ESAM KMT2C DCHS1	3.11e-05	49	65	6	HP:0002779
HumanPheno	Abnormal external genitalia	HSPG2 FAT4 POLR1A WWOX ANK1 BICRA LAMA3 GRB10 ESAM CRPPA SRY CHD7 MSH5 SIM1 RFX7 ADAR CREBBP SIL1 KMT2C KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 PLEC CTNND2 GDF11 PHIP CUX1 SEC23B	3.33e-05	1372	65	33	HP:0000811
HumanPheno	Abnormality of the palpebral fissures	HSPG2 FAT4 HIVEP2 POLR1A WWOX ANK1 BICRA ESAM CHD8 CHD7 SIM1 RFX7 CREBBP EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 DCHS1 FGD1 FGFR3 CTNND2 PHIP CUX1	3.65e-05	880	65	25	HP:0008050
HumanPheno	Abnormal larynx morphology	HSPG2 COL12A1 TRIM2 POLR1A LAMA3 CHD7 RFX7 CREBBP SEC24C FGFR3 PHIP	3.78e-05	201	65	11	HP:0025423
HumanPheno	Abnormal finger morphology	HSPG2 FAT4 COL12A1 HIVEP2 KMT2B POLR1A AFF2 BICRA LAMA3 GRB10 ESAM CRPPA CHD7 SMARCAD1 SIM1 RFX7 ADAR CREBBP SIL1 EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A FGFR3 PLEC LRBA PHIP TBX5	4.11e-05	1385	65	33	HP:0001167
HumanPheno	Cutaneous syndactyly	FAT4 BICRA SMARCAD1 RFX7 CREBBP TP63 DCHS1 TBX5	4.14e-05	103	65	8	HP:0012725
HumanPheno	Choanal atresia or stenosis	FAT4 POLR1A CHD7 EFTUD2 KMT2D SEC24C TP63 DCHS1 FGFR3	4.23e-05	134	65	9	HP:0000416
HumanPheno	Abnormal choanae morphology	FAT4 POLR1A CHD7 EFTUD2 KMT2D SEC24C TP63 DCHS1 FGFR3	4.23e-05	134	65	9	HP:0000415
HumanPheno	Aplasia/hypoplasia affecting bones of the axial skeleton	HSPG2 FAT4 COL12A1 POLR1A WWOX ANK1 BICRA GRB10 TCIRG1 ESAM CHD8 SRY CHD7 SIM1 CREBBP EFTUD2 KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 GDF11 PHIP TBX5	4.39e-05	1008	65	27	HP:0009122
HumanPheno	Abnormality of the urethra	HSPG2 FAT4 WWOX BICRA LAMA3 GRB10 SRY CREBBP KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A PLEC CUX1	4.72e-05	465	65	17	HP:0000795
HumanPheno	Abnormal male external genitalia morphology	HSPG2 FAT4 POLR1A WWOX ANK1 BICRA LAMA3 GRB10 ESAM CRPPA SRY CHD7 MSH5 SIM1 RFX7 ADAR CREBBP KMT2C KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 PLEC CTNND2 GDF11 PHIP CUX1 SEC23B	4.83e-05	1329	65	32	HP:0000032
HumanPheno	Delayed ability to stand	COL12A1 PHEX CLCNKA GAA	5.07e-05	17	65	4	HP:0025335
HumanPheno	Microcephaly	HSPG2 FAT4 FOXRED1 HIVEP2 KMT2B POLR1A WWOX AFF2 ANK1 BICRA ESAM CRPPA CHD8 CHD7 PLEKHG2 RFX7 ADAR ATP10A CREBBP SIL1 EFTUD2 JARID2 LINS1 KMT2C KMT2D SEC24C TRIM8 DCHS1 FGD1 CC2D2A FGFR3 CTNND2	5.85e-05	1341	65	32	HP:0000252
HumanPheno	Midface retrusion	HSPG2 FAT4 POLR1A BICRA EFTUD2 JARID2 LINS1 KMT2C KMT2D DCHS1 FGD1 FGFR3 GDF11	5.88e-05	291	65	13	HP:0011800
HumanPheno	Anal stenosis	FAT4 CHD7 KMT2D TP63 DCHS1	6.05e-05	34	65	5	HP:0002025
HumanPheno	Overfolded helix	HSPG2 BICRA CHD7 CREBBP EFTUD2 KMT2D SEC24C	7.09e-05	82	65	7	HP:0000396
HumanPheno	Decreased head circumference	HSPG2 FAT4 FOXRED1 HIVEP2 KMT2B POLR1A WWOX AFF2 ANK1 BICRA ESAM CRPPA CHD8 CHD7 PLEKHG2 RFX7 ADAR ATP10A CREBBP SIL1 EFTUD2 JARID2 LINS1 KMT2C KMT2D SEC24C TRIM8 DCHS1 FGD1 CC2D2A FGFR3 CTNND2	7.18e-05	1354	65	32	HP:0040195
HumanPheno	Abnormal upper lip morphology	HSPG2 FAT4 HIVEP2 POLR1A WWOX AFF2 ESAM CHD8 CHD7 SIM1 RFX7 CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A GDF11 PHIP CUX1 TBX5	7.90e-05	980	65	26	HP:0000177
HumanPheno	Feeding difficulties	HSPG2 FAT4 FOXRED1 HIVEP2 KMT2B POLR1A WWOX ANK1 BICRA GRB10 ESAM CHD8 CHD7 SIM1 ADAR ATP10A CREBBP PREPL EFTUD2 KMT2D SEC24C CLCNKA ATXN7 TP63 DCHS1 CC2D2A FGFR3 PHIP GAA	8.23e-05	1168	65	29	HP:0011968
HumanPheno	Laryngomalacia	HSPG2 COL12A1 POLR1A CHD7 RFX7 CREBBP SEC24C	8.28e-05	84	65	7	HP:0001601
HumanPheno	Abnormality of the helix	HSPG2 AFF2 BICRA CHD7 CREBBP EFTUD2 KMT2D SEC24C FGFR3 GDF11	8.99e-05	183	65	10	HP:0000380
HumanPheno	Large earlobe	BICRA EFTUD2 KMT2D FGD1 PHIP	9.21e-05	37	65	5	HP:0009748
HumanPheno	Macrocephaly	HSPG2 POLR1A AFF2 BICRA GRB10 TCIRG1 CRPPA CHD8 SIM1 RFX7 JARID2 KMT2C FGD1 CC2D2A FGFR3 PLEC SEC23B	9.40e-05	491	65	17	HP:0000256
HumanPheno	Hypocalcemia	FAT4 TCIRG1 CHD7 RFX7 PREPL PLEKHM1 SEC24C	9.63e-05	86	65	7	HP:0002901
HumanPheno	Increased head circumference	HSPG2 POLR1A AFF2 BICRA GRB10 TCIRG1 CRPPA CHD8 SIM1 RFX7 JARID2 KMT2C FGD1 CC2D2A FGFR3 PLEC SEC23B	1.18e-04	500	65	17	HP:0040194
HumanPheno	Abnormally folded helix	HSPG2 BICRA CHD7 CREBBP EFTUD2 KMT2D SEC24C	1.29e-04	90	65	7	HP:0008544
HumanPheno	Joint hypermobility	FAT4 COL12A1 POLR1A BICRA ESAM CHD7 RFX7 CREBBP JARID2 KMT2D SEC24C TRIM8 DCHS1 FGD1 FGFR3 CTNND2 GDF11 PHIP	1.36e-04	557	65	18	HP:0001382
HumanPheno	Hyperactivity	HSPG2 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 SEC24C TRIM8 FGD1 CACNA1H FGFR3 PHIP	1.39e-04	558	65	18	HP:0000752
HumanPheno	Macule	HSPG2 SMARCAD1 RFX7 ADAR CREBBP KMT2D TP63 FGFR3 PLEC PHIP SEC23B	1.51e-04	234	65	11	HP:0012733
HumanPheno	Generalized osteosclerosis	TCIRG1 PLEKHM1 PHEX	1.58e-04	9	65	3	HP:0005789
HumanPheno	Abnormal hand morphology	HSPG2 FAT4 KMT2B POLR1A WWOX AFF2 BICRA LAMA3 GRB10 SRY CHD7 SIM1 CREBBP SIL1 EFTUD2 PHEX KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 CTNND2 PHIP TBX5	1.59e-04	1082	65	27	HP:0005922
HumanPheno	Abnormal metatarsal morphology	HSPG2 FAT4 CRPPA SRY SIL1 TP63 DCHS1 FGD1 TBX5	1.60e-04	159	65	9	HP:0001832
HumanPheno	Autistic behavior	HSPG2 FOXRED1 HIVEP2 KMT2B WWOX AFF2 BICRA CHD8 SRY CHD7 SIM1 RFX7 CREBBP JARID2 KMT2C KMT2D SEC24C TRIM8 CC2D2A SEC23B	1.84e-04	678	65	20	HP:0000729
HumanPheno	Abnormal hair morphology	HSPG2 FAT4 HIVEP2 KMT2B POLR1A WWOX BICRA LAMA3 TCIRG1 ESAM CHD8 SRY CHD7 SIM1 ADAR ATP10A CREBBP PREPL JARID2 KMT2C KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP SEC23B HR	2.04e-04	1424	65	32	HP:0001595
HumanPheno	Abnormal external nose morphology	HSPG2 HIVEP2 KMT2B POLR1A WWOX BICRA ESAM SIM1 RFX7 ADAR CREBBP EFTUD2 JARID2 KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP CUX1	2.13e-04	916	65	24	HP:0010938
HumanPheno	Hypoplasia of the maxilla	FAT4 POLR1A CREBBP EFTUD2 TP63 DCHS1 FGD1 FGFR3	2.15e-04	130	65	8	HP:0000327
HumanPheno	Hypospadias	HSPG2 FAT4 WWOX BICRA GRB10 SRY CREBBP KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CUX1	2.17e-04	377	65	14	HP:0000047
HumanPheno	Upslanted palpebral fissure	HIVEP2 POLR1A WWOX ANK1 BICRA ESAM SIM1 RFX7 CREBBP EFTUD2 JARID2 SEC24C PHIP	2.32e-04	333	65	13	HP:0000582
HumanPheno	Diagnostic behavioral phenotype	WHRN HSPG2 FOXRED1 HIVEP2 KMT2B WWOX AFF2 BICRA CHD8 SRY CHD7 SIM1 RFX7 CREBBP JARID2 KMT2C KMT2D SEC24C TRIM8 CC2D2A SEC23B	2.38e-04	747	65	21	HP:0025783
HumanPheno	Abnormality of the male genitalia	HSPG2 FAT4 POLR1A WWOX ANK1 BICRA LAMA3 GRB10 ESAM CRPPA SRY CHD7 MSH5 SIM1 RFX7 ADAR CREBBP KMT2C KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CC2D2A FGFR3 PLEC CTNND2 GDF11 PHIP CUX1 SEC23B	2.45e-04	1437	65	32	HP:0010461
HumanPheno	Disinhibition	HSPG2 FAT4 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 LINS1 KMT2C SEC24C TRIM8 DCHS1 FGD1 CACNA1H FGFR3 PHIP	2.50e-04	807	65	22	HP:0000734
HumanPheno	Inappropriate behavior	HSPG2 FAT4 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 LINS1 KMT2C SEC24C TRIM8 DCHS1 FGD1 CACNA1H FGFR3 PHIP	2.50e-04	807	65	22	HP:0000719
HumanPheno	Abnormal response to social norms	HSPG2 FAT4 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 LINS1 KMT2C SEC24C TRIM8 DCHS1 FGD1 CACNA1H FGFR3 PHIP	2.50e-04	807	65	22	HP:5200123
HumanPheno	Social disinhibition	HSPG2 FAT4 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 LINS1 KMT2C SEC24C TRIM8 DCHS1 FGD1 CACNA1H FGFR3 PHIP	2.50e-04	807	65	22	HP:5200029
HumanPheno	Aplasia/Hypoplasia of the maxilla	FAT4 POLR1A CREBBP EFTUD2 TP63 DCHS1 FGD1 FGFR3	2.52e-04	133	65	8	HP:0009117
HumanPheno	Abnormally increased volition	HSPG2 FAT4 HIVEP2 KMT2B WWOX AFF2 CHD8 CHD7 SIM1 RFX7 ATP10A CREBBP JARID2 LINS1 KMT2C SEC24C ATXN7 TRIM8 DCHS1 FGD1 CACNA1H FGFR3 PHIP	2.65e-04	869	65	23	HP:5200263
HumanPheno	Ptosis	HSPG2 FAT4 FOXRED1 KMT2B POLR1A WWOX CHD8 CHD7 ADAR CREBBP PREPL JARID2 KMT2D SEC24C TP63 DCHS1 FGD1 CC2D2A FGFR3 PLEC PHIP	2.72e-04	754	65	21	HP:0000508
HumanPheno	Cleft palate	HSPG2 POLR1A BICRA CRPPA CHD7 RFX7 CREBBP EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A FGFR3 GDF11 TBX5	2.77e-04	643	65	19	HP:0000175
HumanPheno	Abnormal hard palate morphology	HSPG2 POLR1A BICRA CRPPA CHD7 RFX7 CREBBP EFTUD2 JARID2 KMT2C KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A FGFR3 GDF11 TBX5	3.00e-04	647	65	19	HP:0100737
HumanPheno	Abnormal helix morphology	HSPG2 AFF2 BICRA CHD7 CREBBP EFTUD2 KMT2D SEC24C FGFR3 GDF11	3.03e-04	212	65	10	HP:0011039
HumanPheno	Feeding difficulties in infancy	HSPG2 FAT4 POLR1A WWOX GRB10 CHD8 CHD7 SIM1 ATP10A CREBBP EFTUD2 KMT2D SEC24C TP63 DCHS1 CC2D2A PHIP GAA	3.09e-04	594	65	18	HP:0008872
HumanPheno	Carious teeth	WHRN LAMA3 TCIRG1 CREBBP KMT2D SEC24C TP63 FGFR3 PLEC	3.16e-04	174	65	9	HP:0000670
HumanPheno	Failure to thrive	HSPG2 FOXRED1 COL12A1 HIVEP2 POLR1A WWOX BICRA LAMA3 GRB10 TCIRG1 CHD7 SIM1 ADAR CREBBP PREPL SIL1 LINS1 KMT2C KMT2D SEC24C CLCNKA ATXN7 TRIM8 FGD1 LRBA SEC23B GAA	3.28e-04	1128	65	27	HP:0001508
HumanPheno	Abnormal location of ears	HSPG2 FAT4 KMT2B POLR1A BICRA ESAM CRPPA CHD8 SRY CHD7 SIM1 RFX7 ADAR CREBBP PREPL EFTUD2 JARID2 KMT2D SEC24C FGD1 CC2D2A FGFR3 CTNND2 CUX1	3.48e-04	945	65	24	HP:0000357
HumanPheno	Abnormal penis morphology	HSPG2 FAT4 WWOX ANK1 BICRA GRB10 CRPPA SRY CHD7 SIM1 ADAR CREBBP KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CUX1 SEC23B	3.60e-04	712	65	20	HP:0000036
HumanPheno	Displacement of the urethral meatus	HSPG2 FAT4 WWOX BICRA GRB10 SRY CREBBP KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CUX1	3.71e-04	397	65	14	HP:0100627
HumanPheno	Abnormal male urethral meatus morphology	HSPG2 FAT4 WWOX BICRA GRB10 SRY CREBBP KMT2D SEC24C TP63 TRIM8 DCHS1 FGD1 CUX1	3.91e-04	399	65	14	HP:0032076
HumanPheno	Choanal stenosis	FAT4 KMT2D DCHS1 FGFR3	3.93e-04	28	65	4	HP:0000452
HumanPheno	Cutaneous syndactyly of toes	FAT4 SMARCAD1 CREBBP TP63 TBX5	3.94e-04	50	65	5	HP:0010621
HumanPheno	Subcortical heterotopia	FAT4 CRPPA DCHS1	4.02e-04	12	65	3	HP:0032391
HumanPheno	macules	SMARCAD1 RFX7 ADAR CREBBP KMT2D SEC24C TP63 FGFR3 PLEC PHIP SEC23B	4.05e-04	262	65	11	HP:0200031
HumanPheno	Short stature	HSPG2 FAT4 KMT2B POLR1A WWOX AFF2 ANK1 BICRA TCIRG1 ESAM SRY CHD7 SIM1 ADAR CREBBP PREPL SIL1 EFTUD2 PHEX KMT2C PHLDB1 KMT2D SEC24C TP63 DCHS1 FGD1 FGFR3 PLEC CTNND2 CUX1 SEC23B	4.13e-04	1407	65	31	HP:0004322
HumanPheno	Abnormal scrotum morphology	FAT4 WWOX SRY CHD7 SIM1 RFX7 CREBBP FGD1	4.14e-04	143	65	8	HP:0000045
HumanPheno	Polyphagia	HSPG2 CHD8 SIM1 RFX7 ATP10A PREPL	4.28e-04	78	65	6	HP:0002591
HumanPheno	Ureterocele	LAMA3 TP63 TRIM8 PLEC	4.51e-04	29	65	4	HP:0000070
HumanPheno	Hernia of the abdominal wall	HSPG2 FAT4 HIVEP2 POLR1A CHD7 RFX7 CREBBP KMT2C KMT2D SEC24C TP63 TRIM8 FGD1 CC2D2A CTNND2 GDF11	4.54e-04	506	65	16	HP:0004299
HumanPheno	Anteverted nares	HIVEP2 POLR1A WWOX BICRA ESAM SIM1 RFX7 CREBBP EFTUD2 KMT2D TRIM8 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP	4.57e-04	559	65	17	HP:0000463
HumanPheno	Upturned nose	HIVEP2 POLR1A WWOX BICRA ESAM SIM1 RFX7 CREBBP EFTUD2 KMT2D TRIM8 FGD1 CC2D2A FGFR3 PLEC GDF11 PHIP	4.57e-04	559	65	17	HP:0000427
MousePheno	wide sternum	FAT4 DCHS1 FGFR3	7.93e-06	5	131	3	MP:0012279
MousePheno	abnormal vertebrae morphology	HSPG2 FAT4 COL12A1 APAF1 CHD7 DELE1 SMARCAD1 CREBBP PLEKHM1 PHC2 PHEX CER1 PARP4 DCHS1 FGFR3 R3HDM1 GDF11	1.34e-05	546	131	17	MP:0000137
MousePheno	perinatal lethality	HSPG2 FAT4 COL12A1 KMT2B ANK1 APAF1 GRB10 CRPPA SMARCAD1 TNRC6C SIM1 CREBBP SIL1 EFTUD2 JARID2 KMT2C PPP2R5C TP63 SKOR2 DCHS1 FGFR3 VSX2 GDF11 CUX1 SEC23B TBX5	1.48e-05	1130	131	26	MP:0002081
MousePheno	abnormal lumbar vertebrae morphology	FAT4 CHD7 SMARCAD1 PHC2 DCHS1 FGFR3 R3HDM1 GDF11	1.57e-05	119	131	8	MP:0003049
MousePheno	abnormal vertebral column morphology	HSPG2 FAT4 COL12A1 APAF1 CHD7 DELE1 SMARCAD1 CREBBP PLEKHM1 PHC2 PHEX CER1 PARP4 ATXN7 TP63 DCHS1 FGFR3 R3HDM1 GDF11 GAA	4.24e-05	787	131	20	MP:0004703
MousePheno	small clitoris	CHD7 TP63	8.72e-05	2	131	2	MP:0003530
MousePheno	clitoris hypoplasia	CHD7 TP63	8.72e-05	2	131	2	MP:0009101
MousePheno	abnormal nose morphology	HSPG2 APAF1 CHD7 CREBBP PHEX TP63 FGFR3 GDF11 SEC23B	1.15e-04	201	131	9	MP:0002233
MousePheno	abnormal cerebellar cortex morphology	TRIM2 HIVEP2 WWOX ANK1 ADAMTS4 SPTBN2 CHD7 SIL1 ATXN7 STARD9 SKOR2	1.20e-04	300	131	11	MP:0004097
MousePheno	abnormal pectoral girdle bone morphology	HSPG2 FAT4 CHD7 SMARCAD1 CREBBP PHC2 PHEX JARID2 DCHS1 FGFR3 GDF11	1.23e-04	301	131	11	MP:0004508
MousePheno	abnormal Purkinje cell morphology	TRIM2 WWOX ANK1 ADAMTS4 SPTBN2 SIL1 ATXN7 STARD9 SKOR2	1.28e-04	204	131	9	MP:0000877
MousePheno	abnormal compact bone thickness	HSPG2 WWOX SMURF1 TCIRG1 PHEX TLE4 FGFR3	1.48e-04	122	131	7	MP:0000134
MousePheno	abnormal social/conspecific interaction behavior	WHRN ARHGAP32 HIVEP2 WWOX CHD8 SRR CHD7 CREBBP ADORA2A CASKIN1 CCDC157 CUX1 HR	1.61e-04	421	131	13	MP:0002557
MousePheno	abnormal motor coordination/balance	WHRN ARHGAP32 TRIM2 WWOX ANK1 ADAMTS4 SPTBN2 DBNL ADCK2 CHD7 CREBBP PREPL SIL1 KMT2D PPP2R5C ATXN7 STARD9 SKOR2 CTNND2 GAA	1.75e-04	873	131	20	MP:0001516
MousePheno	abnormal cerebellar layer morphology	TRIM2 HIVEP2 WWOX ANK1 ADAMTS4 SPTBN2 SIL1 ATXN7 STARD9 SKOR2	1.83e-04	263	131	10	MP:0009956
MousePheno	abnormal spine curvature	HSPG2 FAT4 COL12A1 SMARCAD1 CREBBP CER1 ATXN7 TP63 DCHS1 FGFR3 GAA	1.99e-04	318	131	11	MP:0004174
MousePheno	abnormal respiratory system morphology	HSPG2 FAT4 WWOX DBNL APAF1 LAMA3 GRB10 CHD7 DOK2 TNRC6C CREBBP PHEX ADORA2A TP63 DCHS1 CC2D2A CACNA1H FGFR3 GDF11 PHIP CUX1 SEC23B	2.10e-04	1027	131	22	MP:0002132
MousePheno	abnormal cartilage development	HSPG2 COL12A1 ITGA10 TCIRG1 PHEX TLE4 CACNA1H FGFR3	2.14e-04	172	131	8	MP:0000164
MousePheno	abnormal compact bone morphology	HSPG2 COL12A1 WWOX SMURF1 TCIRG1 PHEX TLE4 FGFR3	2.14e-04	172	131	8	MP:0003797
MousePheno	abnormal vertebrae development	HSPG2 FAT4 APAF1 DCHS1 FGFR3	2.23e-04	59	131	5	MP:0005225
MousePheno	abnormal cerebellar Purkinje cell layer	TRIM2 WWOX ANK1 ADAMTS4 SPTBN2 SIL1 ATXN7 STARD9 SKOR2	2.26e-04	220	131	9	MP:0000875
MousePheno	abnormal femur head morphology	HSPG2 FGFR3	2.60e-04	3	131	2	MP:0030788
MousePheno	abnormal skeleton development	HSPG2 FAT4 COL12A1 WWOX APAF1 ITGA10 TCIRG1 CREBBP PHEX TLE4 DCHS1 CACNA1H FGFR3	2.89e-04	447	131	13	MP:0002113
MousePheno	abnormal stomach epithelium morphology	CA9 TP63 GDF11 SEC23B	3.44e-04	36	131	4	MP:0000471
Domain	FYrich_C	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	IPR003889
Domain	FYrich_N	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	IPR003888
Domain	FYRC	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	SM00542
Domain	FYRN	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	SM00541
Domain	FYRN	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	PF05964
Domain	FYRC	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	PF05965
Domain	FYRC	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	PS51543
Domain	FYRN	KMT2B KMT2C KMT2D	5.54e-06	5	155	3	PS51542
Domain	GSCR1_dom	BICRA BICRAL	6.84e-05	2	155	2	IPR015671
Domain	GLTSCR1	BICRA BICRAL	6.84e-05	2	155	2	PF15249
Domain	SNF2_N	EP400 CHD8 CHD7 SMARCAD1	1.37e-04	32	155	4	IPR000330
Domain	SNF2_N	EP400 CHD8 CHD7 SMARCAD1	1.37e-04	32	155	4	PF00176
Domain	VWF_A	COL12A1 ITGA10 ITIH5 PARP4 SEC24C SEC23B	1.76e-04	99	155	6	IPR002035
Domain	UBA-like	UBAP2 SMARCAD1 TNRC6C UBASH3A UBXN7	1.90e-04	64	155	5	IPR009060
Domain	Post-SET_dom	KMT2B KMT2C KMT2D	2.90e-04	16	155	3	IPR003616
Domain	PostSET	KMT2B KMT2C KMT2D	2.90e-04	16	155	3	SM00508
Domain	POST_SET	KMT2B KMT2C KMT2D	2.90e-04	16	155	3	PS50868
Domain	-	COL12A1 ITIH5 PARP4 SEC24C SEC23B	3.75e-04	74	155	5	3.40.50.410
Domain	PHOSPHOPANTETHEINE	FASN MEIOC	6.73e-04	5	155	2	PS00012
Domain	EPHD	KMT2B KMT2C KMT2D	7.69e-04	22	155	3	PS51805
Domain	-	DBNL SEC24C SEC23B	9.98e-04	24	155	3	3.40.20.10
Domain	ADF-H/Gelsolin-like_dom	DBNL SEC24C SEC23B	9.98e-04	24	155	3	IPR029006
Domain	Sec23/24_helical_dom	SEC24C SEC23B	1.00e-03	6	155	2	IPR006900
Domain	BRK	CHD8 CHD7	1.00e-03	6	155	2	SM00592
Domain	Sec23_24_beta_S	SEC24C SEC23B	1.00e-03	6	155	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24C SEC23B	1.00e-03	6	155	2	PF04810
Domain	Sec23_trunk	SEC24C SEC23B	1.00e-03	6	155	2	PF04811
Domain	Sec23_helical	SEC24C SEC23B	1.00e-03	6	155	2	PF04815
Domain	BRK_domain	CHD8 CHD7	1.00e-03	6	155	2	IPR006576
Domain	Sec23_BS	SEC24C SEC23B	1.00e-03	6	155	2	PF08033
Domain	Sec23/24_trunk_dom	SEC24C SEC23B	1.00e-03	6	155	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24C SEC23B	1.00e-03	6	155	2	IPR006895
Domain	BRK	CHD8 CHD7	1.00e-03	6	155	2	PF07533
Domain	-	HSPG2 FAT4 COL12A1 LAMA3 LRBA	1.17e-03	95	155	5	2.60.120.200
Domain	VWA	COL12A1 ITGA10 ITIH5 PARP4	1.20e-03	56	155	4	PF00092
Domain	Laminin_G	HSPG2 FAT4 COL12A1 LAMA3	1.37e-03	58	155	4	IPR001791
Domain	CUT	ONECUT1 CUX1	1.40e-03	7	155	2	PS51042
Domain	CUT	ONECUT1 CUX1	1.40e-03	7	155	2	PF02376
Domain	CUT_dom	ONECUT1 CUX1	1.40e-03	7	155	2	IPR003350
Domain	CUT	ONECUT1 CUX1	1.40e-03	7	155	2	SM01109
Domain	VIT	ITIH5 PARP4	1.85e-03	8	155	2	PF08487
Domain	VIT	ITIH5 PARP4	1.85e-03	8	155	2	SM00609
Domain	LAMININ_IVA	HSPG2 LAMA3	1.85e-03	8	155	2	PS51115
Domain	Laminin_B	HSPG2 LAMA3	1.85e-03	8	155	2	PF00052
Domain	LamB	HSPG2 LAMA3	1.85e-03	8	155	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA3	1.85e-03	8	155	2	IPR000034
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RANGAP1 UBAP2 KMT2B EP400 SPTBN2 DBNL CHD8 RFX1 MIDEAS ADAR CREBBP CEP170 KMT2C FASN KMT2D LRBA SAP130 CUX1 DCP1A	1.56e-11	549	163	19	38280479
Pubmed	Human transcription factor protein interaction networks.	HSPG2 ARHGAP32 UBAP2 KMT2B EP400 RADX BICRA CHD8 CHD7 GIGYF1 TNRC6C RFX7 RFX1 MIDEAS CREBBP MRPL2 PCF11 KMT2C C3P1 KMT2D ATXN7 TLE4 UBXN7 CPSF1 R3HDM1 SAP130 CUX1 SEC23B DCP1A	2.67e-11	1429	163	29	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RANGAP1 KMT2B WASHC2C EP400 CHD7 SMARCAD1 RFX7 RFX1 HDAC7 PHC2 EFTUD2 PCF11 FASN KMT2D SEC24C ATXN7 TLE4 CPSF1 PLEC DCP1A	7.57e-10	774	163	20	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN WASHC2C EP400 SMURF1 GRB10 SMARCAD1 TNRC6C PHLDB1 SEC24C STARD9 ZFR2 TLE4 CACNA1H R3HDM1 PLXNB3	1.02e-09	407	163	15	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 HIVEP2 KMT2B GTPBP6 EP400 BICRA GRB10 CHD8 TNRC6C HDAC7 PLEKHM1 SIL1 PHC2 KMT2C FASN PHLDB1 KMT2D CASKIN1 CPSF1 CACNA1H PLEC LRBA HR	2.36e-09	1105	163	23	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FOXO1 ARHGAP32 HIVEP2 UBAP2 DBNL GRB10 GIGYF1 PLEKHG2 RFX7 HDAC7 SHKBP1 CEP170 PHLDB1 STARD9 MPHOSPH9 SSH2 PLEC R3HDM1 SEC23B DCP1A	4.62e-09	861	163	20	36931259
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARHGAP32 FAT4 ADCK2 CHD7 RFX1 CREBBP PREPL PARP4 PHLDB1 KMT2D GUCY1B2 ATXN7 TRIM8 TIGD5 CTNND2 MAML3 CUX1	9.82e-09	638	163	17	31182584
Pubmed	A human MAP kinase interactome.	ARHGAP32 HIVEP2 BICRA SPTBN2 LAMA3 CHD8 NCKAP5 MIDEAS CREBBP KMT2C SIMC1 BICRAL MPHOSPH9 PLEC CUX1	1.11e-08	486	163	15	20936779
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EP400P1 HIVEP2 POLR1A WWOX GTPBP6 BICRA SMURF1 LAMA3 GRB10 MSH5 TNRC6C ATP10A CREBBP PLEKHM1 SIL1 SHKBP1 CEP170 KMT2C PHLDB1 ATXN7 CACNA1H LRBA SAP130 MAML3 CUX1	3.21e-08	1489	163	25	28611215
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	BICRA TNRC6C RFX7 MIDEAS CREBBP HROB TRIM8 MPHOSPH9 R3HDM1	4.62e-08	152	163	9	38360978
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KMT2B EP400 CHD8 CHD7 CREBBP HDAC7 PHC2 JARID2 KMT2D	6.11e-08	157	163	9	30186101
Pubmed	Interaction network of human early embryonic transcription factors.	HIVEP2 KMT2B EP400 BICRA CHD8 CHD7 RFX7 MIDEAS CREBBP KMT2C KMT2D TLE4	1.15e-07	351	163	12	38297188
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	EP400 CHD7 MIDEAS KMT2D TP63 SAP130 CUX1	1.34e-07	83	163	7	28794006
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2B KMT2C KMT2D	4.03e-07	4	163	3	19221051
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	CREBBP KMT2C KMT2D	4.03e-07	4	163	3	28398509
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2C KMT2D	4.03e-07	4	163	3	23129768
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	EP400 CHD8 CHD7 MIDEAS CREBBP PCF11 KMT2D TLE4 SAP130 CUX1	6.11e-07	268	163	10	33640491
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KMT2B WWOX CHD8 CHD7 RFX1 FASN KMT2D TLE4 PLEC LRBA CUX1 DCP1A	7.37e-07	418	163	12	34709266
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXO1 TRIM2 HIVEP2 TACC2 SIM1 ONECUT1 CREBBP KMT2C TRIM8 TIGD5 VSX2 MAML3 PHIP CUX1 DCP1A	1.40e-06	709	163	15	22988430
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2B KMT2C KMT2D	2.00e-06	6	163	3	17021013
Pubmed	CHARGE and Kabuki syndromes: a phenotypic and molecular link.	CHD8 CHD7 KMT2D	2.00e-06	6	163	3	24705355
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RANGAP1 UBAP2 WWOX EP400 BICRA CHD8 CHD7 RFX1 MIDEAS ADAR EFTUD2 PCF11 CEP170 SIMC1 SAP130 PHIP CUX1	2.77e-06	954	163	17	36373674
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	WHRN ARHGAP32 EP400 SPTBN2 GRB10 BICRAL PLXNB3	2.84e-06	130	163	7	12421765
Pubmed	14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.	RANGAP1 DBNL TCIRG1 CEP170 FASN SEC24C KCTD3 SEC23B	2.95e-06	186	163	8	14744259
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	UBAP2 WASHC2C DBNL DOK2 CD5 SIMC1 R3HDM1	3.31e-06	133	163	7	15144186
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2B KMT2C KMT2D	3.49e-06	7	163	3	30604749
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2B KMT2C KMT2D	3.49e-06	7	163	3	19556342
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	CUL1 RANGAP1 CHD8 CHD7 SMARCAD1 EFTUD2 PCF11 PARP4 FASN SEC24C CPSF1 PLEC SEC23B	4.05e-06	582	163	13	20467437
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGAP32 ADAMTS4 SPTBN2 DELE1 ATP10A EFTUD2 PCF11 CEP170 PARP4 KRBA1 SSH2 MAML3	4.05e-06	493	163	12	15368895
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CUL1 KMT2B EP400 BICRA CHD8 CHD7 RFX1 MIDEAS ADAR CREBBP PCF11 CEP170 KMT2C FASN KMT2D BICRAL SAP130 CUX1	4.72e-06	1103	163	18	34189442
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	RANGAP1 EP400 CHD8 SMARCAD1 RFX1 MIDEAS KMT2D UBXN7 SAP130 DCP1A	5.27e-06	341	163	10	32971831
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2B KMT2C KMT2D	5.56e-06	8	163	3	22266653
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2B KMT2C KMT2D	5.56e-06	8	163	3	23130995
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RANGAP1 KMT2B EP400 CHD7 MIDEAS KMT2C SAP130	6.13e-06	146	163	7	23892456
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	RANGAP1 SPTBN2 ADAR EFTUD2 CEP170 FASN PLEC R3HDM1 SEC23B	6.37e-06	274	163	9	34244482
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARHGAP32 UBAP2 AFF2 EP400 BICRA CHD7 SMARCAD1 GUCY1B2 TP63 PLEC SAP130	6.48e-06	430	163	11	35044719
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	RANGAP1 EP400 CHD8 CHD7 RFX1 PHC2 PPP2R5C SAP130 CUX1	8.03e-06	282	163	9	23667531
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2B KMT2C KMT2D	8.32e-06	9	163	3	22665483
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	FOXO1 BMP2K GRB10 GIGYF1 MSH5 TNRC6C SHKBP1 CEP170 HROB PHLDB1 SEC24C KCTD3 MPHOSPH9 SSH2 R3HDM1 SEC23B DCP1A	8.40e-06	1038	163	17	26673895
Pubmed	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.	KMT2B GRB10 MSH5 PLEKHM1 PHC2 HROB TIGD5 IL4I1 SEC23B GPRIN2	9.31e-06	364	163	10	31391242
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	CUL1 GIGYF1 MIDEAS CREBBP PCF11 KMT2C PARP4 KMT2D MEIOC SAP130 MAML3	1.14e-05	457	163	11	32344865
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXO1 CUL1 RANGAP1 EP400 SMARCAD1 RFX1 ADAR CREBBP FASN KMT2D TLE4 SAP130 CUX1 GAA DCP1A	1.36e-05	857	163	15	25609649
Pubmed	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	ARHGAP32 WWOX SRR CREBBP KIF25	1.40e-05	65	163	5	23319000
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RANGAP1 EP400 SPTBN2 SMURF1 CHD7 SIM1 ADAR PHC2 SHKBP1 EFTUD2 PCF11 CEP170 SEC24C KCTD3 CPSF1 PLEC SEC23B	1.43e-05	1082	163	17	38697112
Pubmed	MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.	CER1 KMT2C KMT2D	1.62e-05	11	163	3	37012455
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	CUL1 FAT4 CREBBP	1.62e-05	11	163	3	24349473
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 FAT4 AFF2 EP400 BMP2K LYSMD4 EFTUD2 PCF11 CD5 SEC24C MPHOSPH9 LRBA CUX1 SEC23B	1.94e-05	777	163	14	35844135
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 RANGAP1 POLR1A EP400 DBNL CHD8 CHD7 SMARCAD1 MIDEAS ADAR CREBBP EFTUD2 FASN PHLDB1 SEC24C CPSF1 PLEC PHIP DCP1A	2.09e-05	1353	163	19	29467282
Pubmed	Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.	KMT2B CREBBP KMT2D	2.16e-05	12	163	3	17707229
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	KMT2B KMT2C KMT2D	2.16e-05	12	163	3	27563068
Pubmed	Role of FOXO1A in the regulation of insulin-like growth factor-binding protein-1 in human endometrial cells: interaction with progesterone receptor.	FOXO1 IGFBP1	2.18e-05	2	163	2	15987820
Pubmed	KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.	KMT2D TP63	2.18e-05	2	163	2	29440247
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	2.18e-05	2	163	2	35640156
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	2.18e-05	2	163	2	31924266
Pubmed	β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.	ANK1 SPTBN2	2.18e-05	2	163	2	24603075
Pubmed	CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome.	CHD8 CHD7	2.18e-05	2	163	2	20453063
Pubmed	CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.	CHD7 KMT2D	2.18e-05	2	163	2	28475860
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	2.18e-05	2	163	2	28967912
Pubmed	Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells.	HIVEP2 RFX1	2.18e-05	2	163	2	10642512
Pubmed	Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions.	FAT4 DCHS1	2.18e-05	2	163	2	25355906
Pubmed	A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.	CREBBP KMT2D	2.18e-05	2	163	2	27999180
Pubmed	Restoration of retinal development in Vsx2 deficient mice by reduction of Gdf11 levels.	VSX2 GDF11	2.18e-05	2	163	2	22183392
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	2.18e-05	2	163	2	36601880
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	2.18e-05	2	163	2	28483418
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	2.18e-05	2	163	2	34156443
Pubmed	CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.	LAMA3 CREBBP	2.18e-05	2	163	2	16219677
Pubmed	Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator.	ONECUT1 CREBBP	2.18e-05	2	163	2	15304484
Pubmed	Novel autosomal recessive LAMA3 and PLEC variants underlie junctional epidermolysis bullosa generalized intermediate and epidermolysis bullosa simplex with muscular dystrophy in two consanguineous families.	LAMA3 PLEC	2.18e-05	2	163	2	29797489
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	2.18e-05	2	163	2	27280393
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	2.18e-05	2	163	2	36869380
Pubmed	Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.	CHD8 CHD7	2.18e-05	2	163	2	24211491
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	2.18e-05	2	163	2	35506254
Pubmed	FGFR3 gene mutation plus GRB10 gene duplication in a patient with achondroplasia plus growth delay with prenatal onset.	GRB10 FGFR3	2.18e-05	2	163	2	27370225
Pubmed	Structure of the planar cell polarity cadherins Fat4 and Dachsous1.	FAT4 DCHS1	2.18e-05	2	163	2	36797229
Pubmed	Mammalian cadherins DCHS1-FAT4 affect functional cerebral architecture.	FAT4 DCHS1	2.18e-05	2	163	2	25930014
Pubmed	p63 promotes cell survival through fatty acid synthase.	FASN TP63	2.18e-05	2	163	2	19517019
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	2.18e-05	2	163	2	25346535
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	CUL1 BMP2K TNRC6C SHKBP1 SEC24C MEIOC SIMC1 KCTD3 SEC23B	2.30e-05	322	163	9	39098523
Pubmed	Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.	KMT2B KMT2C KMT2D	2.79e-05	13	163	3	21502505
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	FOXO1 SIM1 TLE4 FGFR3 CUX1 PLXNB3	2.99e-05	126	163	6	16284245
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 ARHGAP32 FAT4 KMT2B WASHC2C NOXA1 GIGYF1 PREPL TENT5B PHC2 ATXN7 R3HDM1	3.24e-05	608	163	12	16713569
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	CREBBP KMT2C KMT2D	3.54e-05	14	163	3	12482968
Pubmed	Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.	CUL1 CPSF1 SAP130	3.54e-05	14	163	3	18173839
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	KMT2B CHD8 KMT2C KMT2D	4.98e-05	43	163	4	33472061
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	RANGAP1 WASHC2C EP400 CHD8 TACC2 CREBBP CEP170 ATXN7 SIMC1 DCP1A	5.05e-05	444	163	10	34795231
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 RANGAP1 UBAP2 SPTBN2 CHD8 CHD7 PREPL EFTUD2 CEP170 SEC24C CASKIN1 DCHS1 SSH2 CTNND2 CUX1	5.17e-05	963	163	15	28671696
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ARHGAP32 RANGAP1 WASHC2C BMP2K SPTBN2 DBNL PLEKHG2 TNRC6C HROB CCDC66 MEIOC SIMC1 MPHOSPH9 PLEC	5.32e-05	853	163	14	28718761
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	KMT2B KMT2C KMT2D	5.41e-05	16	163	3	24368734
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	WWOX WASHC2C BMP2K DBNL CEACAM4 SMURF1 TACC2 CHD7 MSH5 KMT2C PPP2R5C SEC24C CLCNKA TLE4 PLEC DCP1A	5.45e-05	1084	163	16	11544199
Pubmed	Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.	HSPG2 COL12A1 FASN HPR	5.45e-05	44	163	4	31273033
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HSPG2 ARHGAP32 COL12A1 CEACAM4 NCKAP5 CHD7 EFTUD2 FGD1 PLEC	5.81e-05	363	163	9	14691545
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	ARHGAP32 FOXRED1 UBAP2 SPTBN2 ADAR EFTUD2 CEP170 FASN SEC24C CPSF1 PLEC	6.28e-05	551	163	11	34728620
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANGAP1 POLR1A SPTBN2 CHD8 CHD7 CEP170 FASN SEC24C CPSF1 PLEC PHIP SEC23B	6.42e-05	653	163	12	22586326
Pubmed	The PRB-dependent FOXO1/IGFBP-1 axis is essential for progestin to inhibit endometrial epithelial growth.	FOXO1 IGFBP1	6.53e-05	3	163	2	23603247
Pubmed	Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.	CREBBP KMT2D	6.53e-05	3	163	2	34463256
Pubmed	A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin.	FOXO1 GDF11	6.53e-05	3	163	2	34510201
Pubmed	Epigenetic regulation of lncRNA connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes.	TACC2 PPP2R5C	6.53e-05	3	163	2	25884766
Pubmed	Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.	PHEX FGFR3	6.53e-05	3	163	2	21139072
Pubmed	The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription.	FOXO1 IGFBP1	6.53e-05	3	163	2	15890677
Pubmed	Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP.	CREBBP CUX1	6.53e-05	3	163	2	10852958
Interaction	SP7 interactions	CUL1 KMT2B EP400 BICRA CHD7 RFX1 MIDEAS CREBBP PCF11 KMT2C KMT2D TLE4 CPSF1 SAP130 CUX1	2.31e-08	304	161	15	int:SP7
Interaction	FEV interactions	KMT2B EP400 BICRA CHD7 RFX1 MIDEAS CREBBP KMT2C KMT2D TLE4 CUX1	7.37e-07	203	161	11	int:FEV
Interaction	ASF1A interactions	CUL1 KMT2B EP400 RADX BICRA SPTBN2 CHD8 CHD7 FASN KMT2D SAP130 CUX1	7.95e-07	249	161	12	int:ASF1A
Interaction	SOX9 interactions	CUL1 EP400 CHD7 MIDEAS CREBBP KMT2C KMT2D CUX1	1.10e-06	97	161	8	int:SOX9
Interaction	HNF4A interactions	FOXO1 KMT2B EP400 BICRA CHD7 MIDEAS CREBBP KMT2C KMT2D ATXN7 SAP130 CUX1	2.25e-06	275	161	12	int:HNF4A
Interaction	EN1 interactions	EP400 CHD7 MIDEAS KMT2C KMT2D TLE4 SAP130 CUX1	2.86e-06	110	161	8	int:EN1
Interaction	FOXL1 interactions	RANGAP1 CHD7 SMARCAD1 MIDEAS ADAR KMT2C FASN KMT2D TLE4 CUX1	4.09e-06	196	161	10	int:FOXL1
Interaction	TBXT interactions	CHD7 MIDEAS CREBBP KMT2C KMT2D TLE4 SAP130 CUX1	4.26e-06	116	161	8	int:TBXT
Interaction	GATA2 interactions	CUL1 CHD7 MIDEAS CREBBP KMT2C FASN KMT2D TLE4 SAP130 CUX1	4.68e-06	199	161	10	int:GATA2
Interaction	YWHAH interactions	FOXO1 ARHGAP32 HIVEP2 UBAP2 DBNL GRB10 GIGYF1 PLEKHG2 RFX7 CREBBP HDAC7 SHKBP1 EFTUD2 CEP170 PHLDB1 STARD9 CC2D2A MPHOSPH9 SSH2 PLEC LRBA R3HDM1 SEC23B DCP1A	7.32e-06	1102	161	24	int:YWHAH
Interaction	FOXI1 interactions	WWOX CREBBP TENT5B KMT2C FASN KMT2D TLE4	9.03e-06	92	161	7	int:FOXI1
Interaction	STIL interactions	CUL1 ARHGAP32 WWOX WASHC2C TNRC6C SEC24C MPHOSPH9 SEC23B DCP1A	2.27e-05	190	161	9	int:STIL
Interaction	HNF1B interactions	EP400 BICRA CHD7 MIDEAS CREBBP KMT2C KMT2D SAP130 CUX1	2.27e-05	190	161	9	int:HNF1B
Interaction	EYA4 interactions	BICRA TNRC6C RFX7 MIDEAS CREBBP HROB TRIM8 MPHOSPH9 PLEC R3HDM1	2.67e-05	243	161	10	int:EYA4
Interaction	WWTR1 interactions	CUL1 RANGAP1 UBAP2 EP400 DBNL CHD8 ADAR CREBBP CEP170 KMT2D TP63 LRBA CUX1	3.58e-05	422	161	13	int:WWTR1
Interaction	NUP35 interactions	CA9 RANGAP1 GIGYF1 MIDEAS CREBBP PCF11 KMT2C PARP4 KMT2D MEIOC SAP130 MAML3 TBX5	3.76e-05	424	161	13	int:NUP35
Interaction	CRX interactions	EP400 BICRA CHD7 DELE1 MIDEAS CREBBP KMT2C KMT2D ATXN7 UBXN7	3.89e-05	254	161	10	int:CRX
Interaction	RBPJ interactions	CUL1 RANGAP1 KMT2B CHD7 SMARCAD1 ADAR CREBBP MAML3 CUX1 TBX5	3.89e-05	254	161	10	int:RBPJ
Interaction	PAX6 interactions	EP400 BICRA CHD7 MIDEAS CREBBP KMT2C KMT2D TLE4 UBXN7 VSX2 SAP130 CUX1	3.96e-05	366	161	12	int:PAX6
Interaction	TRIM47 interactions	FOXO1 CUL1 EFTUD2 TRIM8 CTNND2	3.97e-05	48	161	5	int:TRIM47
Interaction	SMG7 interactions	CHD8 TNRC6C CREBBP PCF11 FASN KMT2D TLE4 FGFR3 R3HDM1 PHIP DCP1A	5.33e-05	319	161	11	int:SMG7
Interaction	YAP1 interactions	FOXO1 RANGAP1 UBAP2 KMT2B SPTBN2 DBNL SMURF1 CHD8 RFX1 MIDEAS ADAR CREBBP CEP170 KMT2C FASN KMT2D TP63 UBXN7 PLEC SAP130 CUX1 DCP1A	6.16e-05	1095	161	22	int:YAP1
Interaction	PAX7 interactions	CHD7 MIDEAS CREBBP KMT2C KMT2D TLE4 SAP130	6.27e-05	124	161	7	int:PAX7
Interaction	EGR2 interactions	HIVEP2 EP400 BICRA CHD7 MIDEAS CREBBP KMT2C KMT2D	7.12e-05	171	161	8	int:EGR2
Interaction	TLX1 interactions	CHD7 MIDEAS CREBBP KMT2C KMT2D TLE4 SAP130 CUX1	8.37e-05	175	161	8	int:TLX1
Interaction	PAX9 interactions	WWOX CHD7 MIDEAS KMT2C KMT2D TLE4 SAP130	8.46e-05	130	161	7	int:PAX9
Interaction	TEAD1 interactions	CHD7 MIDEAS CREBBP KMT2C FASN KMT2D TP63 CUX1	8.71e-05	176	161	8	int:TEAD1
Interaction	TNRC6A interactions	KMT2B GIGYF1 TNRC6C PCF11 KMT2C HROB MPHOSPH9 PHIP SEC23B DCP1A	8.78e-05	280	161	10	int:TNRC6A
Interaction	NFIX interactions	KMT2B EP400 BICRA RFX1 MIDEAS KMT2C KMT2D SAP130 CUX1	9.04e-05	227	161	9	int:NFIX
Interaction	SLC4A3 interactions	RANGAP1 ANK1 UBASH3A	1.04e-04	12	161	3	int:SLC4A3
Interaction	TOP3B interactions	HSPG2 HIVEP2 UBAP2 KMT2B GTPBP6 EP400 BICRA SPTBN2 GRB10 CHD8 TNRC6C HDAC7 PLEKHM1 SIL1 PHC2 KMT2C FASN PHLDB1 KMT2D CASKIN1 CPSF1 CACNA1H PLEC LRBA SEC23B HR	1.05e-04	1470	161	26	int:TOP3B
Interaction	PML interactions	FOXO1 CUL1 RANGAP1 KMT2B WASHC2C EP400 CHD8 TACC2 CREBBP HDAC7 CEP170 FASN ATXN7 TP63 SIMC1 SAP130 PHIP SEC23B DCP1A	1.71e-04	933	161	19	int:PML
Interaction	CPEB1 interactions	UBAP2 GIGYF1 TNRC6C FASN CPSF1 R3HDM1 DCP1A	1.75e-04	146	161	7	int:CPEB1
Interaction	MEN1 interactions	CUL1 RANGAP1 UBAP2 KMT2B WASHC2C EP400 CHD8 SMARCAD1 RFX1 MIDEAS ADAR EFTUD2 PCF11 KMT2C KMT2D UBXN7 CPSF1 SAP130 CUX1 DCP1A	2.12e-04	1029	161	20	int:MEN1
Interaction	GCM1 interactions	CUL1 MIDEAS CREBBP KMT2C KMT2D	2.12e-04	68	161	5	int:GCM1
Interaction	YWHAQ interactions	FOXO1 ARHGAP32 HIVEP2 UBAP2 SMURF1 ADCK2 GIGYF1 RFX7 HDAC7 EFTUD2 CEP170 FASN PHLDB1 STARD9 MPHOSPH9 SSH2 PLEC LRBA R3HDM1 SEC23B DCP1A	2.32e-04	1118	161	21	int:YWHAQ
Interaction	TNIK interactions	ARHGAP32 TRIM2 SPTBN2 SMURF1 CHD8 EFTUD2 CEP170 SEC24C KXD1 DCHS1 CTNND2	2.53e-04	381	161	11	int:TNIK
Interaction	SMAD3 interactions	FOXO1 CUL1 KMT2B WWOX SMURF1 CHD8 SRY CREBBP PHC2 PARP4 SAP130 SBK3	2.59e-04	447	161	12	int:SMAD3
Interaction	CPEB4 interactions	ARHGAP32 UBAP2 GIGYF1 TNRC6C SHKBP1 R3HDM1 PHIP	2.62e-04	156	161	7	int:CPEB4
Interaction	PAX8 interactions	CHD7 MIDEAS CREBBP KMT2C KMT2D TLE4	2.69e-04	111	161	6	int:PAX8
GeneFamily	Ataxins\|Trinucleotide repeat containing	EP400 TNRC6C KMT2D MAML3	7.97e-06	25	94	4	775
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN2 GRB10 PLEKHG2 PLEKHM1 PHLDB1 FGD1	7.20e-04	206	94	6	682
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B KMT2C KMT2D	7.25e-04	34	94	3	487
GeneFamily	Regulatory factor X family	RFX7 RFX1	7.34e-04	8	94	2	1153
GeneFamily	CUT class homeoboxes and pseudogenes	ONECUT1 CUX1	9.40e-04	9	94	2	527
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	EP400 CHD7 MIDEAS	2.64e-03	53	94	3	532
GeneFamily	Cadherin related	FAT4 DCHS1	3.46e-03	17	94	2	24
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	ZSWIM2 CREBBP	3.88e-03	18	94	2	91
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FOXO1 CUL1 HIVEP2 CREBBP PHC2 PCF11 CEP170 JARID2 TP63 TLE4 BICRAL PHIP	4.23e-07	300	163	12	M8702
Coexpression	GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN	BMP2K CHD7 TNRC6C RFX7 KMT2D STARD9 TRIM8 BICRAL PHIP	4.76e-06	200	163	9	M8997
Coexpression	GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN	FOXO1 BMP2K TACC2 ATP10A PAOX KXD1 CTNND2 CUX1	3.65e-05	199	163	8	M6964
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	PLEKHG2 MIDEAS PHC2 SHKBP1 KMT2D ATXN7 KCTD3 SSH2	3.78e-05	200	163	8	M9463
Coexpression	GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	FOXO1 BMP2K APAF1 GRB10 PLEKHG2 HROB CD5 MPHOSPH9	3.78e-05	200	163	8	M294
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	ARHGAP32 CHD7 PLEKHG2 PREPL PLEKHM1 CER1 CCDC66 PPP2R5C R3HCC1L KXD1 FGD1 CC2D2A FGFR3 MPHOSPH9 R3HDM1 HYI GDF11 MAML3 PHIP CUX1	1.33e-06	780	157	20	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ARHGAP32 AFF2 PLEKHG2 PREPL CER1 CCDC66 MPHOSPH9 LRBA GDF11 MAML3 PHIP	1.13e-05	291	157	11	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 DELE1 DOK2 PLEKHG2 ADORA2A GUCY1B2 CLCNKA PLEC GAA	5.91e-08	200	164	9	88d713dfc792e7609bf7ecfb28f87cb748088570
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXO1 WWOX JARID2 KMT2C SSH2 LRBA MAML3 CUX1	6.11e-07	193	164	8	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 PREPL CCDC66 OSGEPL1 CASKIN1 LRBA SBK3	1.78e-06	155	164	7	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AFF2 ADAMTS4 ITGA10 DCHS1 CACNA1H TBX5 HR	2.48e-06	163	164	7	8f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RANGAP1 UBASH3A PPP2R5C CD5 ATXN7 CASKIN1 IL4I1	2.59e-06	164	164	7	30c3c25b05a403a509b2e755c2f0878fecb10a02
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOXO1 HSPG2 POLR1A ADAMTS4 ESAM VSTM2B STARD9	3.55e-06	172	164	7	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	WWOX JARID2 MPHOSPH9 CTNND2 R3HDM1 MAML3 CUX1	5.93e-06	186	164	7	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	COPD-Epithelial-ATI\|COPD / Disease state, Lineage and Cell class	HSPG2 COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	5.93e-06	186	164	7	df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	WWOX JARID2 MPHOSPH9 CTNND2 R3HDM1 MAML3 CUX1	5.93e-06	186	164	7	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	HSPG2 TRIM2 SPTBN2 TACC2 ITIH5 CLCNKA CACNA1H	6.36e-06	188	164	7	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 WHRN NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.06e-06	191	164	7	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 WWOX GRB10 NCKAP5 SSH2 LRBA CUX1	7.30e-06	192	164	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	ITGA10 TCIRG1 SIM1 HDAC7 SHKBP1 PHLDB1	7.34e-06	126	164	6	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	FOXO1 DOK2 UBASH3A FAAH2 PPP2R5C CD5 ATXN7	8.92e-06	198	164	7	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	9.22e-06	199	164	7	456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	9.22e-06	199	164	7	5263338242f95c04690d0795749ccc20b0d19f7a
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 WWOX RFX7 KMT2C SSH2 LRBA MAML3	9.22e-06	199	164	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	9.22e-06	199	164	7	c11365653c69a5dfb37946231f8af05149a61a71
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 COL12A1 ESAM NCKAP5 CHD7 HDAC7 KMT2C	9.53e-06	200	164	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19-Mast_cells-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	AFF2 BMP2K ENPP3 CRLF2 CACNA1H MAML3	2.48e-05	156	164	6	bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell	COVID-19-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	AFF2 BMP2K ENPP3 CRLF2 CACNA1H MAML3	2.48e-05	156	164	6	159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 DOK2 ATP10A KRBA1 SSH2 GDF11	2.57e-05	157	164	6	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 DOK2 ATP10A KRBA1 SSH2 GDF11	2.57e-05	157	164	6	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 DOK2 ATP10A KRBA1 SSH2 GDF11	2.57e-05	157	164	6	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EP400 BICRA JARID2 CC2D2A RASSF4 IL4I1	2.57e-05	157	164	6	d8e283414a770f05d71f0455d0822e9a9660b115
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EP400 BICRA JARID2 CC2D2A RASSF4 IL4I1	2.57e-05	157	164	6	165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	NUP210L NOXA1 NCKAP5 CRLF2 CTNND2 IL4I1	3.17e-05	163	164	6	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ITGA10 CRPPA SRY CLCNKA STARD9 DCP1A	3.17e-05	163	164	6	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	WHRN ANK1 FAAH2 PHEX CD5 TP63	3.28e-05	164	164	6	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP2K ENPP3 CRLF2 PARP4 CACNA1H MAML3	3.39e-05	165	164	6	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP2K ENPP3 CRLF2 PARP4 CACNA1H MAML3	3.39e-05	165	164	6	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP2K ENPP3 CRLF2 PARP4 CACNA1H MAML3	3.39e-05	165	164	6	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS4 VSTM2B UBASH3A CASKIN1 CTNND2 KIF25	3.51e-05	166	164	6	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS4 VSTM2B UBASH3A CASKIN1 CTNND2 KIF25	3.51e-05	166	164	6	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS4 VSTM2B UBASH3A CASKIN1 CTNND2 KIF25	3.51e-05	166	164	6	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS4 VSTM2B UBASH3A CASKIN1 CTNND2 KIF25	3.51e-05	166	164	6	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXO1 FAT4 COL12A1 ITGA10 HPR TBX5	4.71e-05	175	164	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 COL12A1 LAMA3 NCKAP5 CTNND2 GPRIN2	4.86e-05	176	164	6	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM2 SPTBN2 SIM1 ITIH5 FAAH2 CLCNKA	4.86e-05	176	164	6	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AFF2 NCKAP5 ITIH5 STARD9 CACNA1H TBX5	5.18e-05	178	164	6	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCIRG1 DOK2 ATP10A ITIH5 HPR GAA	5.18e-05	178	164	6	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	WHRN ANK1 FAAH2 PHEX TP63 TRIM8	5.18e-05	178	164	6	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	ZSWIM2 CRLF2 RASSF4 VSX2 IL4I1 HR	5.68e-05	181	164	6	94680f8dbdf22d83801abc0819417751d363fb12
ToppCell	COPD-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	5.86e-05	182	164	6	e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNRC6C PREPL FAAH2 LINS1 CCDC66 CD5	6.22e-05	184	164	6	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 AFF2 ADAMTS4 STARD9 CACNA1H TBX5	6.22e-05	184	164	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	COL12A1 LAMA3 NCKAP5 ATP10A CTNND2 GPRIN2	6.41e-05	185	164	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Control-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	6.41e-05	185	164	6	0563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA9 FAT4 ANK1 LAMA3 NCKAP5 CHD7	6.41e-05	185	164	6	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 COL12A1 ESAM ITIH5 IGFBP1 KIF25	6.61e-05	186	164	6	a906020a8df6fcca474b278f746c553b177a56b4
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 NOXA1 LAMA3 SRR TACC2 DCHS1	6.61e-05	186	164	6	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	AFF2 ADAMTS4 NCKAP5 PHLDB1 CACNA1H TBX5	6.61e-05	186	164	6	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	Control-Epithelial-ATI\|Control / Disease state, Lineage and Cell class	COL12A1 LAMA3 NCKAP5 TACC2 TENT5B GPRIN2	6.80e-05	187	164	6	fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	AFF2 ADAMTS4 ESAM NCKAP5 CACNA1H TBX5	6.80e-05	187	164	6	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.01e-05	188	164	6	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WHRN ADAMTS4 NCKAP5 CHD7 PHLDB1 PLXNB3	7.22e-05	189	164	6	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AFF2 ADAMTS4 PHLDB1 STARD9 CACNA1H TBX5	7.43e-05	190	164	6	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.43e-05	190	164	6	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AFF2 ADAMTS4 PHLDB1 STARD9 CACNA1H TBX5	7.43e-05	190	164	6	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 ESAM NCKAP5 ITIH5 TLE4 CTNND2	7.43e-05	190	164	6	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WHRN NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.43e-05	190	164	6	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNRC6C UBASH3A PREPL LINS1 CCDC66 CD5	7.65e-05	191	164	6	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.65e-05	191	164	6	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	7.65e-05	191	164	6	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIVEP2 TNRC6C UBASH3A FAAH2 LINS1 CD5	7.87e-05	192	164	6	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	8.10e-05	193	164	6	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	AFF2 ADAMTS4 ESAM NCKAP5 CACNA1H TBX5	8.33e-05	194	164	6	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HIVEP2 TNRC6C UBASH3A LINS1 PPP2R5C CD5	8.57e-05	195	164	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 LAMA3 NCKAP5 CTNND2 GPRIN2	8.57e-05	195	164	6	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 LAMA3 NCKAP5 CTNND2 GPRIN2	8.57e-05	195	164	6	b65511770ed67f7447847e2187555b362988af45
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 COL12A1 LAMA3 NCKAP5 TENT5B GPRIN2	9.06e-05	197	164	6	734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FOXO1 HIVEP2 CHD7 UBASH3A LINS1 CD5	9.06e-05	197	164	6	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 WWOX SMURF1 LRBA MAML3 CUX1	9.32e-05	198	164	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 COL12A1 GRB10 ESAM ITIH5 IGFBP1	9.58e-05	199	164	6	9c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 COL12A1 GRB10 ESAM ITIH5 IGFBP1	9.58e-05	199	164	6	72b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	9.58e-05	199	164	6	236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	9.58e-05	199	164	6	c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCell	Macroglial\|World / cells hierarchy compared to all cells using T-Statistic	FOXO1 NCKAP5 CHD7 PHLDB1 FGFR3 PLXNB3	9.85e-05	200	164	6	e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	AFF2 NCKAP5 PHLDB1 STARD9 CACNA1H TBX5	9.85e-05	200	164	6	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 ADAMTS4 ITIH5 STARD9 CACNA1H TBX5	9.85e-05	200	164	6	d70bad979299615fcba707ba21296020918705e6
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	9.85e-05	200	164	6	86ec951234015ced7126b016199e5869a0f22478
ToppCell	mLN-Dendritic_cell-cDC2\|Dendritic_cell / Region, Cell class and subclass	CEACAM4 DOK2 RFX7 ATP10A PLEKHM1 SIL1	9.85e-05	200	164	6	e3f7852aaa26a9b3e626d85e40afde799e873045
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 TRIM2 ENPP3 TACC2 FAAH2 MAML3	9.85e-05	200	164	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 ADAMTS4 ESAM ITIH5 CACNA1H TBX5	9.85e-05	200	164	6	8158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CA9 FAT4 ANK1 LAMA3 NCKAP5 CHD7	9.85e-05	200	164	6	501a3b93624df463458a35d3e6648d4ccc941724
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 ADAMTS4 ITIH5 STARD9 CACNA1H TBX5	9.85e-05	200	164	6	38c21ec379005f688df33aea65237a063c476c2e
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CA9 FAT4 ANK1 LAMA3 NCKAP5 CHD7	9.85e-05	200	164	6	d1f36a8232411933b1494168ec912fd0e5246428
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AFF2 NCKAP5 PHLDB1 STARD9 CACNA1H TBX5	9.85e-05	200	164	6	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	LETM2 AFF2 EXTL1 PLEKHG2 PAOX CCDC24	9.85e-05	200	164	6	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CA9 FAT4 ANK1 LAMA3 NCKAP5 CHD7	9.85e-05	200	164	6	140aff451cd58e1d544ee668e49e37e577f6f068
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 ADAMTS4 ESAM ITIH5 CACNA1H TBX5	9.85e-05	200	164	6	600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	AFF2 NCKAP5 PHLDB1 STARD9 CACNA1H TBX5	9.85e-05	200	164	6	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	9.85e-05	200	164	6	c239e6f5d23caa9a59b83e9b352b2d6a691dcb28
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CA9 FAT4 ANK1 LAMA3 NCKAP5 CHD7	9.85e-05	200	164	6	85bfa7f4dd07a4d4a88330e88f5886fd1ecfdeeb
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ITGA10 ESAM ATP10A ITIH5 IGFBP1	9.85e-05	200	164	6	061ba851f941c616ddb462512e826c412881c3ce
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CA9 HSPG2 SPTBN2 EXTL1 FGFR3	1.24e-04	131	164	5	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ITGA10 ESAM CRPPA TP63 TLE4	1.64e-04	139	164	5	2fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell	343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ITGA10 ESAM CRPPA TP63 TLE4	1.64e-04	139	164	5	5970a654c64e3b54f9d18c102f5b125eec892fc5
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A	TRIM2 AFF2 CEACAM4 LAMA3 PHEX ADORA2A CD5 FGD1 CPSF1 FGFR3 HR	2.08e-07	199	163	11	122_UP
Drug	Zidovudine, AZT [30516-87-1]; Down 200; 15uM; MCF7; HT_HG-U133A	WHRN RANGAP1 HIVEP2 BICRA SMURF1 ITGA10 ADCK2 R3HCC1L TBX5 HR	1.64e-06	197	163	10	3211_DN
Disease	neuroimaging measurement	PDXDC1 UBAP2 KMT2B WWOX DCDC1 GRB10 NCKAP5 TACC2 CHD7 SMARCAD1 MSH5 ITIH5 EFTUD2 TP63 TLE4 PDXDC2P CC2D2A FGFR3 SSH2 PLEC	1.36e-06	1069	159	20	EFO_0004346
Disease	congenital heart disease (implicated_via_orthology)	KMT2B CHD8 CHD7 KMT2C KMT2D SAP130	2.02e-06	69	159	6	DOID:1682 (implicated_via_orthology)
Disease	bipolar disorder	WHRN LETM2 HIVEP2 UBAP2 POLR1A BICRA SPTBN2 HDAC7 KMT2D STARD9 TLE4 TRIM8 BICRAL PLEC	3.20e-06	577	159	14	MONDO_0004985
Disease	Squamous cell carcinoma of esophagus	FAT4 WWOX CREBBP KMT2C FASN KMT2D	1.30e-05	95	159	6	C0279626
Disease	Van Maldergem Wetzburger Verloes syndrome	FAT4 DCHS1	2.89e-05	2	159	2	C1832390
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	2.89e-05	2	159	2	DOID:0080598 (implicated_via_orthology)
Disease	Van Maldergem syndrome	FAT4 DCHS1	2.89e-05	2	159	2	cv:C1832390
Disease	Lambert-Eaton Myasthenic Syndrome	PREPL PLEC	2.89e-05	2	159	2	C0022972
Disease	Myasthenic Syndrome	PREPL PLEC	2.89e-05	2	159	2	C0549225
Disease	thanatophoric dysplasia (implicated_via_orthology)	HSPG2 FGFR3	2.89e-05	2	159	2	DOID:13481 (implicated_via_orthology)
Disease	Periventricular gray matter heterotopia	FAT4 DCHS1	2.89e-05	2	159	2	C1849173
Disease	outer ear morphology trait	HIVEP2 LRBA CUX1	3.26e-05	12	159	3	EFO_0007664
Disease	cortical thickness	HSPG2 COL12A1 KMT2B WWOX DCDC1 NUP210L SPTBN2 NCKAP5 TACC2 CHD7 SMARCAD1 PLEKHM1 ITIH5 PHLDB1 KCTD3 FGFR3 SSH2 PLEC	3.36e-05	1113	159	18	EFO_0004840
Disease	Congenital small ears	CHD7 EFTUD2 KMT2D FGFR3	7.04e-05	41	159	4	C0152423
Disease	Carcinoma, Transitional Cell	APAF1 CREBBP KMT2C FGFR3	7.04e-05	41	159	4	C0007138
Disease	Osteopetrosis, Autosomal Recessive 6	TCIRG1 PLEKHM1	8.63e-05	3	159	2	C1969093
Disease	Osteopetrosis - intermediate type	TCIRG1 PLEKHM1	8.63e-05	3	159	2	C0432261
Disease	Heterotopia, Periventricular, Autosomal Recessive	FAT4 DCHS1	8.63e-05	3	159	2	C1842563
Disease	Congenital Foot Deformity	TP63 FGD1	1.72e-04	4	159	2	C0016508
Disease	autism spectrum disorder (implicated_via_orthology)	ARHGAP32 CHD8 CHD7 CREBBP LRBA CTNND2	1.81e-04	152	159	6	DOID:0060041 (implicated_via_orthology)
Disease	brain measurement, neuroimaging measurement	PDXDC1 WWOX DCDC1 TMEM74 GRB10 NCKAP5 ITIH5 ATXN7 FGFR3 SSH2 PLEC	2.07e-04	550	159	11	EFO_0004346, EFO_0004464
Disease	Diffuse Large B-Cell Lymphoma	FOXO1 RANGAP1 CREBBP KMT2D	2.24e-04	55	159	4	C0079744
Disease	red blood cell density measurement	PDXDC1 FOXO1 POLR1A WWOX WASHC2C DCDC1 ANK1 EP400 BMP2K RFX7 PHC2 CC2D2A SSH2 PLEC	3.08e-04	880	159	14	EFO_0007978
Disease	cortical surface area measurement	TRIM2 WWOX DCDC1 ENPP3 CRPPA NCKAP5 CHD7 SMARCAD1 MSH5 PLEKHM1 PHC2 ITIH5 TLE4 TRIM8 FGFR3 MPHOSPH9 SSH2 CUX1	3.56e-04	1345	159	18	EFO_0010736
Disease	Sezary Syndrome	CREBBP KMT2C KMT2D	4.08e-04	27	159	3	C0036920
Disease	Human papillomavirus infectious disease (is_implicated_in)	ADAR FGFR3	4.27e-04	6	159	2	DOID:11166 (is_implicated_in)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD7	5.95e-04	7	159	2	DOID:0050834 (implicated_via_orthology)
Disease	insulin sensitivity measurement, insulin response measurement	ANK1 GRB10	7.91e-04	8	159	2	EFO_0004471, EFO_0008473
Disease	Ventricular Dysfunction	ADORA2A GAA	7.91e-04	8	159	2	C0242973
Disease	heart function measurement	CLCNKA PLEC TBX5	8.13e-04	34	159	3	EFO_0004311
Disease	Spinocerebellar Ataxia Type 2	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0752121
Disease	Spinocerebellar Ataxia Type 1	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0752120
Disease	Spinocerebellar Ataxia Type 5	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0752123
Disease	Spinocerebellar Ataxia Type 7	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0752124
Disease	Ataxia, Spinocerebellar	WWOX SPTBN2 ATXN7	8.13e-04	34	159	3	C0087012
Disease	Spinocerebellar Ataxia Type 4	WWOX SPTBN2 ATXN7	8.85e-04	35	159	3	C0752122
Disease	lung non-small cell carcinoma (is_implicated_in)	CA9 MSH5 PAOX KMT2C KMT2D	9.60e-04	139	159	5	DOID:3908 (is_implicated_in)
Disease	insulin response measurement	ANK1 GRB10	1.01e-03	9	159	2	EFO_0008473
Disease	thyroxine measurement	LAMA3 SIM1 ADORA2A STARD9	1.07e-03	83	159	4	EFO_0005130
Disease	obesity (implicated_via_orthology)	FAT4 ADAMTS4 SIM1 HPR DCHS1 PLXNB3	1.13e-03	215	159	6	DOID:9970 (implicated_via_orthology)
Disease	glucagon-like peptide-1 measurement	COL12A1 BICRA	1.26e-03	10	159	2	EFO_0008465
Disease	white matter microstructure measurement	KMT2B DCDC1 NCKAP5 PLEKHM1 EFTUD2 SSH2 PLEC CCDC157	1.30e-03	390	159	8	EFO_0005674
Disease	46,XY partial gonadal dysgenesis	WWOX SRY	1.54e-03	11	159	2	C4510744
Disease	mean arterial pressure	WASHC2C DCDC1 HDAC7 TENT5B CEP170 MPHOSPH9 LRBA HYI PHIP	1.60e-03	499	159	9	EFO_0006340
Disease	Craniofacial Abnormalities	HSPG2 APAF1 PHEX TP63 FGD1	1.60e-03	156	159	5	C0376634
Disease	prostate cancer (is_marker_for)	FOXO1 KMT2B KMT2C KMT2D FGD1	1.60e-03	156	159	5	DOID:10283 (is_marker_for)
Disease	osteoarthritis, knee	DCDC1 FGFR3 MPHOSPH9 PLEC PCSK9	1.69e-03	158	159	5	EFO_0004616
Disease	esophagus squamous cell carcinoma (is_implicated_in)	WWOX KMT2C KMT2D	1.85e-03	45	159	3	DOID:3748 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	TRIM2 SIM1 HPR PCSK9	2.05e-03	99	159	4	EFO_0004611, EFO_0007878
Disease	interleukin 6 receptor subunit alpha measurement	NUP210L ADAR	2.16e-03	13	159	2	EFO_0008187
Disease	Skin Abnormalities	APAF1 TP63	2.16e-03	13	159	2	C0037268
Disease	complement factor H-related protein 3 measurement	COL12A1 WWOX ONECUT1 PPP2R5C TP63	2.27e-03	169	159	5	EFO_0600056
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	TRIM2 SIM1 HPR PCSK9	2.29e-03	102	159	4	EFO_0004329, EFO_0004611
Disease	blood phosphate measurement	HSPG2 DCDC1 ENPP3 SPTBN2 CUX1	2.58e-03	174	159	5	EFO_0010972
Disease	eosinophil count	FOXO1 HIVEP2 WWOX ADAMTS4 SMURF1 GRB10 CHD7 DOK2 GIGYF1 UBASH3A CRLF2 PHC2 CD5 CACNA1H MPHOSPH9 PLEC CUX1	2.85e-03	1488	159	17	EFO_0004842
Disease	Lymphoma, Follicular, Grade 2	CREBBP KMT2D	2.89e-03	15	159	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	CREBBP KMT2D	2.89e-03	15	159	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	CREBBP KMT2D	2.89e-03	15	159	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	CREBBP KMT2D	2.89e-03	15	159	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	CREBBP KMT2D	2.89e-03	15	159	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	CREBBP KMT2D	2.89e-03	15	159	2	C0079758
Disease	Intellectual Disability	HIVEP2 CHD8 PREPL LINS1 KMT2C FASN TRIM8 PHIP	3.03e-03	447	159	8	C3714756
Disease	phosphorus measurement	ENPP3 PHEX	3.29e-03	16	159	2	EFO_0004861
Disease	Eye Abnormalities	APAF1 CRPPA	3.72e-03	17	159	2	C0015393
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	KMT2B RFX7	3.72e-03	17	159	2	DOID:0060307 (is_implicated_in)
Disease	squamous cell carcinoma (is_implicated_in)	WWOX KMT2C	4.17e-03	18	159	2	DOID:1749 (is_implicated_in)
Disease	disease progression measurement	HIVEP2 WWOX TLE4	4.40e-03	61	159	3	EFO_0008336
Disease	serum albumin measurement	PDXDC1 TRIM2 TCIRG1 CRPPA DOK2 ADAR PLEKHM1 HPR PLEC	4.95e-03	592	159	9	EFO_0004535
Disease	docosahexaenoic acid measurement	PDXDC1 CTNND2 CUX1 PCSK9	5.02e-03	127	159	4	EFO_0007761
Disease	Lymphoma, Follicular	CREBBP KMT2D	5.14e-03	20	159	2	C0024301
Disease	Adenocarcinoma of lung (disorder)	SRR CREBBP FASN TP63 FGFR3	5.28e-03	206	159	5	C0152013
Disease	lobe attachment	FAT4 HIVEP2 WWOX LRBA CUX1	5.38e-03	207	159	5	EFO_0007667

Protein segments in the cluster

Peptide	Gene	Start	Entry
NGHLLGRQPFPNIVQ	APAF1	551	O14727
GQTPTLGQPEARALH	CEP170	1531	Q5SW79
IAQGAQVQLQHPGTP	EP400	201	Q96L91
SNAGVSRAQVPGHQP	ADCK2	286	Q7Z695
LQQPQSGGPQGHRHV	CHD8	291	Q9HCK8
GQLHVHQNNVPGLPV	CEACAM4	136	O75871
GLVPRRHAPSGNQQP	CXorf49;	451	A8MYA2
GEQVSLRLNGHPPGV	ADORA2A	331	P29274
PVQGQQQGPVLHSVT	CUX1	1016	P39880
GNCNNGPVTIPQRIH	AFF2	1226	P51816
PQNGITPLHIASRRG	ANK1	236	P16157
LTISLGGIPPNQAHR	FAT4	4341	Q6V0I7
GGIPPNQAHRDAQTA	FAT4	4346	Q6V0I7
PPRLQLVAQSGGQHC	CD5	156	P06127
LSGQPQASHLPGQQI	CREBBP	2321	Q92793
ANSNGPFQPVVLLHI	PPP2R5C	16	Q13362
PGSHRTANQAQVVPG	C1orf147	41	Q96MC9
PHLVATSPAGEGQRQ	CER1	61	O95813
NTVLPGRPRQNSLHG	BMP2K	1096	Q9NSY1
TPQHDQIQTQPLGKG	DCP1A	401	Q9NPI6
PGRGQASSAHQPQER	CCDC157	736	Q569K6
IQERLIPGQQHPGQQ	CHD7	491	Q9P2D1
SVPLQRTGSQHGPQN	CTNND2	466	Q9UQB3
QAGRGLPVQPHSGRS	ATP10A	1466	O60312
RNNGHSVQLTLPPGL	CA9	196	Q16790
PNAGVITNAPLQRHF	R3HCC1L	126	Q7Z5L2
GHPVSQPVLQQQGYI	R3HDM1	621	Q15032
PQNGINHPGITALAQ	RANGAP1	216	P46060
QQPQGPGANHDARSL	NOXA1	221	Q86UR1
SRGHTPTQPGALNQR	HSPG2	646	P98160
STPLHGQPLVVLQGN	HSPG2	1021	P98160
RPVPSGTQQRHQGSE	HSPG2	1716	P98160
PPGHSVQDGVLRIQN	HSPG2	3441	P98160
NGNITAQGPSIQPVH	RASSF4	101	Q9H2L5
SLQSVAGTEPGRHPQ	CRPPA	31	A4D126
RILQGPHANPVAVPQ	RADX	626	Q6NSI4
GTSVGIVQAHNPPGR	DCHS1	806	Q96JQ0
GGIVPPAAQQLHREN	OSGEPL1	76	Q9H4B0
AGVARSQPPVAHAGQ	CASKIN1	441	Q8WXD9
SHAAPQLVLGVQGPN	DCDC1	1176	M0R2J8
RDPAGLQHVQPAGQD	DOK2	376	O60496
QPGNTVLHPGTRLIQ	LETM2	61	Q2VYF4
HPSPSGVGNRRLQEN	KRBA1	286	A5PL33
HVFSQGVQVNPGLIP	KMT2C	2981	Q8NEZ4
QGRHQPISVGVAPIA	LINS1	56	Q8NG48
HQPPQAGAGDVVLLQ	LYSMD4	61	Q5XG99
RAQAPNHRVQLGGLG	GIGYF1	796	O75420
PQNQVTLRGRVPHLG	LAMA3	1111	Q16787
QAGQPRLTKQHFPQG	MAML3	991	Q96JK9
QNLTHPLLLQVGEGP	ITIH5	861	Q86UX2
PNVVPVSALRGHGLQ	GTPBP6	431	O43824
NPANPVQRILGGHLD	HPR	96	P00739
GVNQLHFIPVDLGAP	CPSF1	631	Q10570
AVLVPAGAPHQVQGL	HR	1116	O43593
PRGQPNQCVGHREAS	PCSK9	581	Q8NBP7
LLPGHHPRQEQGQVT	PLXNB3	531	Q9ULL4
ALPGEQQPLHALTRG	IGFBP1	86	P08833
DLSHVQPGSPAINGR	KXD1	151	Q9BQD3
EPQSPRIQNIGEQGH	PDXDC1	76	Q6P996
EPQSPRIQNIGEQGH	PDXDC2P	76	Q6P474
HGQLLGTAREPNPSV	ONECUT1	261	Q9UBC0
KQQISGIQPHGLPNA	MPHOSPH9	301	Q99550
ISRQHEQPGQGIAPD	LRBA	1276	P50851
AQGAQVQLQHPGTPI	EP400P1	191	Q6ZTU2
PAGILPHQQSGRSLE	HROB	401	Q8N3J3
QLHPGPCGLQAVSQR	KMT2B	1441	Q9UMN6
GNVRPLLHGSPVQNI	PARP4	431	Q9UKK3
LQLPHQPLQGGDVVT	CRLF2	341	Q9HC73
GLNNSHKVQGVVPVP	ARHGAP32	1331	A7KAX9
NAVNVRHDQSGRGPP	ATXN7	766	O15265
GPQHQQASRFDIPLG	PCF11	1096	O94913
GQIAPPSHLIRVEGN	TP63	256	Q9H3D4
PAGATHILVRQQGNP	ADAMTS4	706	O75173
PIVGHVQVAQVPGRG	HYI	206	Q5T013
GHAQQTSAVNGRPLP	FOXO1	526	Q12778
PSNVSGGLLVHRQTP	BICRAL	246	Q6AI39
SQHVIRSGDPPGNFQ	CC2D2A	391	Q9P2K1
SQGLQRGFQHPSPRG	ADAR	101	P55265
PGAPSHQAGVQIQQT	C3P1	116	Q6ZMU1
HLTGNGRTVGLLPPQ	COL12A1	2106	Q99715
RIQPAPNNGTHGSLN	ENPP3	526	O14638
VHQSNQARGAGVPPS	CUL1	56	Q13616
FDQNGVVGPHPLVVN	FOXRED1	416	Q96CU9
THLVQQANPRGSAGP	GDF11	356	O95390
NPGHLSQNRGISPEI	CCDC66	746	A2RUB6
LPLGIQVVAGPFNDH	FAAH2	496	Q6GMR7
PSCRLQGVPHVGANV	ESAM	156	Q96AP7
HQQGASRPGPRDAQA	GAA	56	P10253
FGHQVNRQVFRQGPP	MIDEAS	221	Q6PJG2
GTQSGVRPHPAQRIA	ITGA10	586	O75578
TVPLLQNGQHARSQP	GRB10	76	Q13322
QNGQHARSQPRASGP	GRB10	81	Q13322
LPLAQGGHRPLSRAQ	HDAC7	471	Q8WUI4
HRPILQAGLPANQTA	FGFR3	251	P22607
LGSSPVHRAQLQPGG	GPRIN2	146	O60269
GGSNVHIILRPNTQP	FASN	396	P49327
LQAQPPGRHLFSGQL	B3GNT6	236	Q6ZMB0
AAPHTGGQLIANPIL	BICRA	501	Q9NZM4
DPSAVQGQGPGHRQR	CACNA1H	491	O95180
SQAQGHPGIQTPQRS	SEC24C	191	P53992
RVLLAQPHQGGPAVA	SBK3	56	P0C264
VQHPETVGSGPQLFQ	KCTD3	401	Q9Y597
PNHRQRPLGSSTQGL	CCDC24	231	Q8N4L8
QPPLVQQQGAGSEHI	DBNL	346	Q9UJU6
QIHFQASLPAGPQRV	DELE1	101	Q14154
LTFRIGNHPGVLNPS	NUP210L	731	Q5VU65
PNNTGSILRHLGAVP	JARID2	896	Q92833
GSHPPVQGQLSLQNT	IL4I1	546	Q96RQ9
IHGPSRGNPVFQLAA	PAOX	71	Q6QHF9
PQVLGVRIQNGRHPL	MSH5	551	O43196
GTQDGVHVQEPRPQA	PLEKHM1	366	Q9Y4G2
SPGRRQAQAAPSQGH	PLEKHM1	501	Q9Y4G2
QQLGSNGFPLRSTHP	MEIOC	681	A2RUB1
HQAGTQLNRSPLLGP	TNRC6C	781	Q9HCJ0
RQAVINGPNVHPGAS	POLR1A	481	O95602
QEGNNGPHLIVVPAS	SMARCAD1	541	Q9H4L7
VAHQPVVRQCGPQTG	TBX5	461	Q99593
TPQVQRERGPQGQGH	NCKAP5	556	O14513
AGAPTGTVPQQLQVH	RFX1	221	P22670
EGSQPRPGLHQGNRI	FGD1	96	P98174
GGVPVPIGNHAQRVA	GUCY1B2	446	O75343
QNVGLVAVGHSLPPS	SIM1	206	P81133
NRHSLVGPQQLGGRP	SHKBP1	141	Q8TBC3
PGSAHVQSRTPQGGL	SIMC1	411	Q8NDZ2
PGQAVPAGSHVRLNL	SIL1	81	Q9H173
LVNQHPIGPFPRVQS	WHRN	671	Q9P202
VHPNQEPAVIAGQGT	SRR	151	Q9GZT4
LGQHPQQLQPRTTIG	STARD9	3996	Q9P2P6
PGNPAGHAEQVQARL	KIF25	251	Q9UIL4
PHLGQILGETPQNLS	SPATA31C1	521	P0DKV0
APGQLRQHSPQPGVA	EXTL1	211	Q92935
VNQHNTPIPQGGRGA	SEC23B	466	Q15437
DVRGSLQTPQNRPHG	SMURF1	216	Q9HCE7
HGRGNFPTLSVQPRQ	TENT5B	71	Q96A09
QALQAEPPSRAPGHQ	CLCNKA	601	P51800
NIQPSPAHETGQGIV	PHC2	511	Q8IXK0
RQQHQSQAVTVPPPG	UBAP2	441	Q5T6F2
VQPNGSPRGVQAQLH	ZFR2	306	Q9UPR6
VHSPPNVGLRRSGQI	PHIP	681	Q8WWQ0
GEPSQPLLGQQRLEH	SPTBN2	2146	O15020
APGLAVAPRQQHGRT	SSH2	1386	Q76I76
GPGIPRHARQINTLN	TLE4	471	Q04727
SPPSGQAVLLRQRHG	VSTM2B	241	A6NLU5
RHIQGIQPAPISTQG	SAP130	556	Q9H0E3
LQGLPHFSVNLGVQP	nan	56	Q6ZSV7
QIGAHSPPQFRVNGA	PHEX	706	P78562
AHPLGALPVGTLINN	MRPL2	181	Q5T653
LSPRGVTSNAVHPGN	WWOX	311	Q9NZC7
GAISPNGHRPQLRAA	WASHC2C	1051	Q9Y4E1
QTPNIILDIQPGGNH	PREPL	676	Q4J6C6
NQHPVPRGLAPNQES	TACC2	2591	O95359
PRGLAPNQESHLQVP	TACC2	2596	O95359
FGRLTPVSPVQHQGA	RFX7	1021	Q2KHR2
GVHGQQRAPRDAPVA	PYCARD-AS1	31	I3L0S3
RRTPHVQAVQGPLGS	PLEC	111	Q15149
LVNGNHTPQTATRGP	PHLDB1	166	Q86UU1
PGHANLKPNQVGQVI	SKOR2	31	Q2VWA4
RGIHRVQTPQPGTND	ZSWIM2	111	Q8NEG5
VRTDPGTATNHQGLP	UBXN7	371	O94888
GHLPPINAASSPQQR	SRY	181	Q05066
TLLPEQGGSRHVQAP	PLEKHG2	936	Q9H7P9
QGGSRHVQAPAATPL	PLEKHG2	941	Q9H7P9
FPPGLLHSGNNQITA	TMEM74	81	Q96NL1
GQLQRPTGVAVHPSG	TRIM2	531	Q9C040
RQHGVPLSGPLIQAQ	TIGD5	136	Q53EQ6
VAQEPLHRGGGQIIP	EFTUD2	796	Q15029
AVEGQVQLPSPHQGS	TMEM169	6	Q96HH4
PARVQEPHQNPLGSA	HIVEP2	2351	P31629
STQHLVALPGGAQPV	TRIM8	421	Q9BZR9
QAPGGPHQDLRVNFV	TCIRG1	156	Q13488
VHNLTPEPGNVTIRG	nan	51	Q6ZRX8
PEPGNVTIRGVHNLT	nan	71	Q6ZRX8
VTIRGVHNLTPEPGN	nan	76	Q6ZRX8
QVPGHGPNLRLSNLT	UBASH3A	196	P57075
VEQLTRLQHPGPQGQ	TTLL13	611	A6NNM8
QSVHLQPLGRASGPL	VSX2	101	P58304
PAGPAQFIELRHNVQ	KMT2D	2871	O14686
QVAVLQQQHPGALGP	KMT2D	3806	O14686
PGHLDQVNGQVVPEA	KMT2D	4396	O14686
GRHFQTLGQPLVGTP	NEXN-AS1	96	Q8NBZ9